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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 37 records · Page 2

Morphological Changes in Rat Vestibular System Following Weightlessness

Mammalian gravity receptors (maculas) are morphologically organized for weighted, parallel distributed processing of information. There are two basic circuits: 1) highly channeled, type I cell to calyx; and 2) distributed modifying, type II cells to calyces and processes. The latter circuit should be the more adaptable since it modifies final output. To test this hypothesis, rats were flown in microgravity for 9 days aboard a space shuttle and euthanized shortly after landing. Hair cells and ribbon synapses from maculas of 3 flight and 3 ground control rats were studied ultrastructurally in blocks of 50 serial sections. Synapses increased by approximately 41% in type I cells and by approximately 55% in type II cells in flight animals. There was a shift toward the spherular form of ribbon synapse in both types of hair cells in flight animals. Current findings tend to support the stated hypothesis and indicate that mature utricular hair cells retain synaptic plasticity, permitting adaptation to an altered gravitational environment.

Ross, Muriel D.↗

Heterococcus endolithicus sp. nov. (Xanthophyceae) and other terrestrial Heterococcus species from Antarctica: morphological changes during life history and response to temperature

Strains of Heterococcus endolithicus sp. nov., H. pleurococcoides Pitschmann, H. caespitosus Vischer, and H. protonematoides Vischer isolated from terrestrial habitats in Antarctica were studied in culture. Morphology of the algae changes with stage in life history. The characteristic branching patterns are not present in very young or old cultures. Filament formation is suppressed when cultures are grown outside their optimal temperature range.

Non-NASA Center↗

Novel inverse oxide/metal catalysts for methanol synthesis: impact of oxide–metal interactions and reversible morphological changes

Inverse oxide/metal catalysts have proved to be excellent systems for the generation of methanol by CO 2 hydrogenation or the partial oxidation of methane. These systems can exhibit unique structural and chemical properties due to the nano size of the oxide component and strong oxide–metal interactions. Recent studies for ZnO/Cu, CeO 2 /Cu, TiO 2/ Cu, MgO/Cu, In 2 O 3 /Cu, and In 2 O 3 /Au catalysts have shown large variations in the composition and morphology of the oxide overlayer as a function of temperature and chemical environment. These oxide–metal interfaces are able to react with CO 2 and CH 4 at room temperature, and both reactants have a strong influence on the physical and chemical properties of the catalysts. Under reaction conditions, switches between oxide–metal and metal–metal interfaces can take in the catalyst surface. A dynamic behavior that can be linked to a high selectivity for methanol production over systems such as ZnO/Cu, CeO 2 /Cu and In 2 O 3 /Au. Finally, this type of correlation deserves additional systematic studies since it could be a powerful tool for designing highly efficient catalysts for methanol synthesis.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

α1-and β-adrenergic antagonist labetalol induces morphological changes in human erythrocytes

Highlights: • Labetalol is one of the most used drugs for the treatment of hypertension. • Structural and thermotropic perturbations in DMPC and DMPE lipid bilayers were induced by labetalol. • Labetalol produced morphological alterations in human erythrocytes inducing the formation of stomatocytes. Labetalol is one of the most used drugs for the treatment of hypertension. This molecule is able to bind to both alpha-1 (α1) and beta (β) adrenergic receptors present in vascular smooth muscle among other tissues. It has been determined that human erythrocytes possess both alpha receptors and beta-adrenergic receptors expressed on their surface. The objective of this work was to study the effect of labetalol on the morphology of human erythrocytes. To accomplish this goal, human erythrocytes and model membranes built of dimyristoylphosphatidylcholine (DMPC) and dimyristoylphosphatidylethanolamine (DMPE) were used. These lipid species are present in the outer and inner monolayers of the red blood cell membrane, respectively. Our findings obtained by X-ray diffraction and differential scanning calorimetry (DSC) indicate that labetalol interacted with both lipids in a process dependent on concentration. In fact, at low concentrations labetalol preferentially interacted with DMPE. On the other hand, results obtained by scanning electron microscopy (SEM) showed that labetalol alters the normal biconcave form of erythrocytes to stomatocytes and knizocytes (cells with one or more cavities, respectively). According to the bilayers couple hypothesis, this result implied that the drug inserted in the inner monolayer of the human erythrocyte membrane.

60 APPLIED LIFE SCIENCES↗

Study of plasma induced nanostructure formation and surface morphology changes on tungsten and stainless steel at atmospheric pressure

The formation of nanostructures such as “fuzz,” holes, and flakes was observed on tungsten and stainless steel anodes in a 1 atm glow discharge with helium as the feed gas. The structures exhibited morphology similar to the tungsten fuzz growth observed in experiments that simulate wall conditions in fusion reactors, suggesting that similar physics may be present in both scenarios. The anode surface temperature ranged between 1000 and 1300 K with an ion fluence rate of order 10 24 s -1 m -2 . In this work, scanning electron microscope and transmission electron microscope were used to characterize the evolution of nanostructure formation as a function of time. Observed nanostructures were found to vary with the morphology of the discharge plasma attachment. The composition of the structures was found to be predominantly the native metal by using energy dispersive x-ray spectroscopy. This work gives some insight into the formation of nanostructures at atmospheric pressure, which not only has applications for material processing, but also provides potentially another avenue to study fuzz formation processes relevant to fusion plasma-wall interactions.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

Morphological Changes in the NGC 6251 Jet

The giant radio galaxy NGC 6251 is a particularly good object for observational tests of relativistic jet models. Due to its high declination and similar 0.5 Jy radio nucleus, high quality VLBI images of the central regions of the source can be made with northern hemisphere arrays. In addition, the large-scale radio morphology strongly suggests that the radio axis lies close to the plane of the sky, so Doppler boosting should be less extreme than in the core-dominated superluminal sources. Earlier 18-cm VLBI observations of NGC 6251 revealed an unexpectedly large jet/counterjet brightness ratio and small transverse motion of a feature in the parsec-scale jet. These early results are difficult to reconcile with the simplest symmetric relativistic jet models.

Wehrle, A. E.↗

Automated Scoring of Morphological Changes in Images of Pentaerythritol Tetranitrate

Recent advances in characterization techniques that generate large datasets of material microstructure images require robust, automated image-processing. We applied an unsupervised anomaly detection method called feature anomaly detection system (FADS) to automatically detect and quantify microstructure changes in images of the explosive pentaerythritol tetranitrate (PETN) aged at various temperatures. We demonstrated the FADS approach on two-dimensional images extracted from computed tomography scans, but the same technique can be readily applied to other imaging modalities. FADS calculates anomaly scores on the basis of differences in filter activations of nominal and test data in pretrained convolutional neural networks. The FADS scores successfully differentiated between pristine PETN and PETN aged at a temperature where material coarsening occurred. Morphological metric analysis of segmented images verified observed trends in FADS scores as a function of aging temperature and aging time, specifically by calculating volume fractions, specific boundary lengths, two-point correlation functions, and local thicknesses. Here, the FADS technique has two important advantages compared to traditional morphological analysis: First, it uses grayscale images as input, rather than images that are segmented to separate the appropriate phases; and second, FADS scores capture any type of changes among image sets, rather than requiring prior knowledge or selection of a relevant set of metrics.

Accelerated aging↗

Morphological changes in the NGC 6251 jet

The giant radio galaxy NGC 6251 is a particularly good object for observational tests of relativistic jet models. Due to its high declination and approximately 0.5 Jy radio nucleus, high-quality Very Long Baseline Interferometry (VLBI) images of the central regions of the source can be made with northern hemisphere arrays. In addition, the large-scale radio morphology strongly suggests that the radio axis lies close to the plane of the sky, so Doppler boosting should be less extreme than in the core-dominated superluminal sources. Earlier 18 cm VLBI observations of NGC 6251 revealed an unexpectedly large jet/counterjet brightness ratio and small transverse motion of a feature in the parsec-scale jet. These early results are difficult to reconcile with the simplest symmetric relativistic jet models. In this paper we present a third-epoch 18 cm VLBI image of the parsec-scale radio jet in NGC 6251, and compare jet morphology over a 5 year time span. The jet shows a minor brightness peak at nearly the same distance from the core as the '25 mas knot' seen in the first- and second-epoch VLBI images. This feature is much less pronounced in the third epoch, and a relatively bright, new knot has appeared approximately 12 mas from the core. If this new component had a constant brightness during the 5 years separating the first and third observing epochs, then it must have moved away from the core with an apparent speed of at least 1.2c (compared with an upper limit of 0.23c for motion of the 25 mas knot). However, we cannot yet rule out a local brightening of the inner jet in favor of a new moving component. We determine a lower limit for the jet/couterjet brightness ratio of 100:1 within 6 mas of the core. We also present a new Very Large Array (VLA) image of the kpc-scale jet with 3 sec resolution, made from data obtained during the VLBI observations. The rate of decrease in jet surface brightness from parsec to kiloparsec scales is similar to jets in known superluminal radio sources.

Jones, Dayton L.↗

Chemical and morphological changes of reusable surface insulation coatings as a function of convectively heated cyclic testing

The effects of convective heating upon reusable surface insulation coatings were studied utilizing scanning electron microscopy, X-ray fluorescence, and X-ray diffraction. Samples of coated silica, mullite, and ceramic mullite fiber were cycled in an arc plasma stream up to 15 times for 15 minutes per cycle at surface temperatures simulating those on the space shuttle vehicle. The surfaces of ceramic mullite fiber and mullite coatings were roughened substantially by the convectively heated environment while the silica was significantly smoothed after testing. Scanning electron microscopy also showed surface cracking of varying degrees in all of the coatings. The surface chemistry of the coatings as examined by X-ray fluorescence revealed that significant changes in composition were occurring during cycling, particularly within the mullite coating.

Leiser, D. B.↗

Catecholamines of the adrenal medula and their morphological changes during adaptation to repeated immobilization stress

Changes of the adrenal medulla of rats were studied in the course of adaptation to repeated immobilization stress. An increase in the number of cells in the adrenal medulla was found in the adapted animals; this increase was confirmed by weight indices of the medulla and by cell counts per surface unit. Simultaneous karyometric measurements of the nuclei of adrenal medulla cells and an analysis of the catecholamine contents in the adrenals explain the increased activity of the adrenal medulla in the course of adaptation.

Kvetnansky, R.↗

Morphological changes in neurons of the hind limb reflex arc during long term immobilization

Twelve adult rabbits were immobilized for 9 to 31 days, followed by histological study of the nerve processes of lumbar vertebra 7 and sacral vertebra 1, the sciatic nerve and the motor endings of the thigh muscles. In the spinal ganglia, dystrophic changes of increasing severity with immobilization time were found, including pericellular edema, vacuolized neuroplasm, pycnotic changes, cytolysis and destruction. Chromatophilic matter decreased and was partly bleached, and amitotic division occurred. A portion of the sciatic nerve fibers were argentophilic, and some fragmentary decomposition occurred. Considerable dystrophic changes occurred in the motor nerve endings.

Tkachenko, Z. Y.↗