Transient-State Analysis of Human Isocitrate Dehydrogenase I: Accounting for the Interconversion of Active and Non-Active Conformational States
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A closed-form expression for the steady-state output signal-to-noise ratio (SNR) of an n-element adaptive array excited by one desired narrow-band signal and K - 1 narrow-band jammers is obtained. This is facilitated by representing each excitation by a complex n-dimensional vector - the excitation vector. It is shown that the important system parameters are functions of scalar products of pairs of these excitation vectors. In particular, the normalized output SNR of the array is shown to be the ratio of determinants whose elements involve these scaler products. Such determinants are also shown to be involved in the expressions for the optimal array weights.
The periodic steady state response of a high pressure oxygen turbopump (HBOTP) of a Space Shuttle main engine (SSME), involving a clearance between the bearing and housing carrier, is sought. A harmonic balance method utilizig Fast Fourier Transform (FFT) algorithm is developed for the analysis. An impedance method is used to reduce the number of degrees of freedom to the displacements at the bearing clearance. Harmonic and subharmonic responses to imbalance for various system parameters are studied. The results show that the computational technique developed in this study is an effective and flexible method for determining the stable and unstable periodic response of complex rotor-housing systems with clearance type nonlinearity.
We consider a variant of the well-known Gauss-Seidel method for the solution of Markov chains in steady state. Whereas the standard algorithm visits each state exactly once per iteration in a predetermined order, the alternative approach uses a dynamic strategy. A set of states to be visited is maintained which can grow and shrink as the computation progresses. In this manner, we hope to concentrate the computational work in those areas of the chain in which maximum improvement in the solution can be achieved. We consider the adaptive approach both as a solver in its own right and as a relaxation method within the multi-level algorithm. Experimental results show significant computational savings in both cases.
Four wire Wye connected ac power systems exhibit peculiar steady state fault characteristics when the fourth wire of three phase induction motors is connected. The loss of one phase of power source due to a series or shunt fault results in currents higher than anticipated on the remaining two phases. A theoretical approach to compute the fault currents and voltages is developed. A FORTRAN program is included in the appendix.
The severe North Atlantic storm which damaged the ocean liner Queen Elizabeth 2 (QE2) was studied to assess the impact of remotely sensed marine surface wind data obtained by SEASAT-A, on sea state specifications and forecasts. Alternate representations of the surface wind field in the QE2 storm were produced from the SEASAT enhanced data base, and from operational analyses based upon conventional data. The wind fields were used to drive a high resolution spectral ocean surface wave prediction model. Results show that sea state analyses would have been vastly improved during the period of storm formation and explosive development had remote sensing wind data been available in real time. A modest improvement in operational 12 to 24 hour wave forecasts would have followed automatically from the improved initial state specification made possible by the remote sensing data in both numerical and sea state prediction models. Significantly improved 24 to 48 hour wave forecasts require in addition to remote sensing data, refinement in the numerical and physical aspects of weather prediction models.
Two new concepts of control for VTOL aircraft remote lift fans are analyzed and discussed. Both concepts employ flow transfer among lift fans located in separate parts of the aircraft in order to obtain attitude control moments in hover and low-speed flight. The results presented are from a digital computer analysis of the YJ97/LF460 remote drive turbofan, although qualitative conclusions should apply to any remote fan system. The basic operating principles of the two systems are described, and their steady-state moment generating capabilities are discussed. Lift-recovery strategies for component failures are also analyzed.
The Chemical Instrumentation Test and Evaluation 3 (CITE 3) NO-NO2 database has provided a unique opportunity to examine important aspects of tropospheric photochemistry as related to the rapid cycling between NO and NO2. Our results suggest that when quantitative testing of this photochemical system is based on airborne field data, extra precautions may need to be taken in the analysis. This was particularly true in the CITE 3 data analysis where different regional environments produced quite different results when evaluating the photochemical test ratio (NO2)(sub expt)/(NO2)(sub calc), designated here as R(sub E)/R(sub C). The quantity (NO2)(sub Calc) was evaluated using the following photostationary state expression: (NO2)(sub Calc) = k(sub 1)(O3) + k(sub 4)(HO2) + k(sub 5)(CH3O2) + k(sub 6)(RO2))(NO)(sub Expt)/J(sub 2). The four most prominent regional environmental data sets identified in this analysis were those labeled here as free-tropospheric northern hemisphere (FTNH), free-tropospheric tropical northern hemisphere (FTTNH), free-tropospheric southern hemisphere (FTSH), and tropical-marine boundary layer (plume) (TMBL(P)). The respective R(sub E)/R(sub C) mean and median values for these four data subsets were 1.74, 1.69; 3.00, 2.79; 1.01, 0.97; and 0.99, 0.94. Of the four data subsets listed, the two that were statistically the most robust were FTNH and FTSH; for these the respective R(sub E)/R(sub C) mean and standard deviation of the mean values were 1.74 +/- 0.07 and 1.01 +/- 0.04. The FTSH observations were in good agreement with theory, whereas those from the FTNH data set were in significant disagreement. An examination of the critical photochemical parameters O3, UV(zenith), NO, NO2, and non-methane hydrocarbons (NMHCs) for these two databases indicated that the most likely source of the R(sub E)/R(sub C) bias in the FTNH results was the presence of a systematic error in the observational data rather than a shortening in our understanding of fundamental photochemical processes. Although neither a chemical nor meteorological analyses of these data identified this error with complete certainty, they did point to the three most likely possibilities: (1) an NO2 interference from a yet unidentified NO(y) species: (2) the presence of unmeasured hydrocarbons, the integrated reactivity of which would be equivalent to approximately 2.7 parts per billion by volume (ppbv) of toluene; or (3) some combination of points (1) and (2). Details concerning hypotheses (1) and (2) as well as possible ways to minimize these problems in future airborne missions are discussed.
Abstract We present a turbulent kinetic energy (TKE) closure scheme for the stably stratified atmosphere in which the mixing lengths for momentum and heat are not parameterized in the same manner. The key difference is that, while the mixing length for heat tends toward the stability independent mixing length for momentum in neutrally stratified conditions, it tends toward one based on the Brunt–Väisälä time scale and square root of the TKE in the limit of large stability. This enables a unique steady-state solution for TKE to be obtained, which we demonstrate would otherwise be impossible if the mixing lengths were the same. Despite the model’s relative simplicity, it is shown to perform reasonably well with observational data from the 1999 Cooperative Atmosphere–Surface Exchange Study (CASES-99) using commonly employed model constants. Analyzing the scaling behavior of the nondimensional velocity and potential temperature gradients, or of the stability (correction) functions, reveals that for large stability the present model scales in the same manner as the first-order operational scheme of Viterbo et al. Alternatively, it appears as a blend of two cases of the TKE closure scheme of Baas et al. Critically, because a unique steady-state TKE can be obtained, the present model avoids the nonphysical behavior identified in one of the cases of Baas et al.
Quantum calculations show that ethylenediamine and crown ethers polarize and displace valence electrons of alkali metals to the periphery of the formed complex. The nature of the building blocks of expanded metals and electrides is discussed.
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Movement of forward heat shield in Apollo command module turbulent reverse flow wake
An analytical method has been developed for studying the combined effects of rotational coupling and nonlinear aerodynamics on aircraft response for specified control inputs. The method involves the simultaneous solution of two nonlinear equations which are functions of angle of attack, roll rate, and the control inputs. The method is applied to a number of maneuvers for a fighter type aircraft. Time history responses verified the usefulness of the analysis for predicting a variety of response characteristics caused by interacting nonlinear aerodynamic and inertial effects, including spin conditions.
An analytical method was developed for studying the combined effects of rotational coupling and nonlinear aerodynamics on aircraft response for specified control inputs. The method involves the simultaneous solution of two nonlinear equations which are functions of angle attack, roll rate, and control inputs. The method was applied to a number of maneuvers for a fighter-type aircraft. Time history responses verified the usefulness of the analysis for predicting a variety of response characteristics caused by interacting nonlinear aerodynamic and inertial effects, including spin conditions.
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