Larvicidal Activity of Constituents from the Main Brazilian Propolis Types: Green, Red, and Brown against Aedes aegypti
Not Available
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗
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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.
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Origins of heat transport anisotropy in MoTe2 and other bulk van der Waals materials
Knowledge of how heat flows anisotropically in van der Waals (vdW) materials is crucial for thermal management of emerging 2D materials devices and design of novel anisotropic thermoelectric materials. Despite the importance, anisotropic heat transport in vdW materials is yet to be systematically studied and is often presumably attributed to anisotropic speeds of sound in vdW materials due to soft interlayer bonding relative to covalent in-plane networks of atoms. In this work, we investigate the origins of the anisotropic heat transport in vdW materials, through time-domain thermoreflectance (TDTR) measurements and first-principles calculations of anisotropic thermal conductivity of three different phases of MoTe 2 . MoTe 2 is ideal for the study due to its weak anisotropy in the speeds of sound. We find that even when the speeds of sound are roughly isotropic, the measured thermal conductivity of MoTe 2 along the c-axis is 5–8 times lower than that along the in-plane axes. We derive meaningful characteristic heat capacity, phonon group velocity, and relaxation times from our first principles calculations for selected vdW materials (MoTe 2 , BP, h-BN, and MoS 2 ), to assess the contributions of these factors to the anisotropic heat transport. Interestingly, we find that the main contributor to the heat transport anisotropy in vdW materials is anisotropy in heat capacity of the dominant heat-carrying phonon modes in different directions, which originates from anisotropic optical phonon dispersion and disparity in the frequency of heat-carrying phonons in different directions. Further, the discrepancy in frequency of the heat-carrying phonons also leads to ~2 times larger average relaxation times in the cross-plane direction, and partially explains the apparent dependence of the anisotropic heat transport on the anisotropic speeds of sound. This work provides insight into understanding of the anisotropic heat transport in vdW materials.
36 MATERIALS SCIENCE↗
Genomics discovery of giant fungal viruses from subsurface oceanic crustal fluids
Abstract The oceanic igneous crust is a vast reservoir for microbial life, dominated by diverse and active bacteria, archaea, and fungi. Archaeal and bacterial viruses were previously detected in oceanic crustal fluids at the Juan de Fuca Ridge (JdFR). Here we report the discovery of two eukaryotic Nucleocytoviricota genomes from the same crustal fluids by sorting and sequencing single virions. Both genomes have a tRNATyr gene with an intron (20 bps) at the canonical position between nucleotide 37 and 38, a common feature in eukaryotic and archaeal tRNA genes with short introns (<100 bps), and fungal genes acquired through horizontal gene transfer (HGT) events. The dominance of Ascomycota fungi as the main eukaryotes in crustal fluids and the evidence for HGT point to these fungi as the putative hosts, making these the first putative fungi-Nucleocytoviricota specific association. Our study suggests active host-viral dynamics for the only eukaryotic group found in the subsurface oceanic crust and raises important questions about the impact of viral infection on the productivity and biogeochemical cycling in this ecosystem.
Bhattacharjee, Ananda S.↗
Topics and Considerations for Developing State Geothermal Regulations
The intent of this document is to provide guidance to states for developing geothermal regulations that would be inclusive of all geothermal technologies (e.g., conventional and non-conventional power production and direct-use applications) with applicability in all states. As part of this project, the NREL project team reviewed and catalogued existing state and federal geothermal regulations, compiled best practices from geothermal and other extractive industries, and established a Geothermal Regulatory Stakeholder Working Group (SWG) to advise and review the geothermal regulatory guidance. The SWG met approximately monthly over the course of one year to review and discuss specific topics as relevant to this geothermal regulatory guidance. This report is broken into five main sections, which were identified in coordination with the SWG as the main topics for inclusion. Within these sections, a list of considerations within each category were identified and, in some cases, relevant examples from existing state and federal geothermal regulations are included to further illustrate the proposed considerations. This report includes the following topics: geothermal resource definition; leasing process; exploration approval process; drilling/wellfield development approval process; and underground injection control process.
15 GEOTHERMAL ENERGY↗
PSEC5 Physical Verification
Ultra-Fast timing detectors, having a time resolution of 10pSec or less, are becoming increasingly important for many scientific disciplines, including High Energy Physics, Nuclear Physics, Medical Imaging and more. When developing ultra-fast detectors such as MCPs, LAPPDs, LGADs, SNSPDs, it is necessary to have access to a readout system that is low power, can support many channels and is cost effective. The PSEC5 chip was an application specific integrated circuit (ASIC) developed by the pioneering group of Prof. Henry Frisch at University of Chicago and micro electronic engineers at Fermi National Accelerator Laboratory. Three boards were designed, two to implement the readout system for an LAPPD and one to only characterize the PSEC1 chip. The main goal of the project shifted to setting up a testing environment to focus on the characterization of the chip. My student and I tested and characterized this ASIC using the third chip-on-board printed circuit board. Results show the successful fabrication and operation of some of the key building blocks and lead to the suggestions on modification for the second iteration of the chip.
Rico Aniles, H. D. [Unlisted]↗
The Mira-Titan Universe. III. Emulation of the Halo Mass Function
We construct an emulator for the halo mass function over group and cluster mass scales for a range of cosmologies, including the effects of dynamical dark energy and massive neutrinos. The emulator is based on the recently completed Mira-Titan Universe suite of cosmological N-body simulations. The main set of simulations spans 111 cosmological models with 2.1 Gpc boxes. We extract halo catalogs in the redshift range z = [0.0, 2.0] and for masses M-200c >= 10(13)M(circle dot)/h. The emulator covers an eight-dimensional hypercube spanned by {Omega(m)h(2), Omega(b)h(2), Omega(nu)h(2), sigma(8), h, n(s), w(0), w(a)}; spatial flatness is assumed. We obtain smooth halo mass functions by fitting piecewise second-order polynomials to the halo catalogs and employ Gaussian process regression to construct the emulator while keeping track of the statistical noise in the input halo catalogs and uncertainties in the regression process. For redshifts z less than or similar to 1, the typical emulator precision is better than 2% for 10(13)-10(14)M(circle dot)/h and <10<^> M similar or equal to 101(circle dot)(54)/h. For comparison, fitting functions using the traditional universal form for the halo mass function can be biased at up to 30% at M similar or equal to 10(144)M(circle dot)/h for z = 0. Our emulator is publicly available at https://github.com/SebastianBocquet/MiraTitanHMFemulator.
cosmology: theory↗
Topics and Considerations for Developing State Geothermal Regulations
The intent of this document is to provide guidance to states for developing geothermal regulations that would be inclusive of all geothermal technologies (e.g., conventional and non-conventional power production and direct-use applications) with applicability in all states. As part of this project, the NREL project team reviewed and catalogued existing state and federal geothermal regulations, compiled best practices from geothermal and other extractive industries, and established a Geothermal Regulatory Stakeholder Working Group (SWG) to advise and review the geothermal regulatory guidance. The SWG met approximately monthly over the course of one year to review and discuss specific topics as relevant to this geothermal regulatory guidance. This report is broken into five main sections, which were identified in coordination with the SWG as the main topics for inclusion. Within these sections, a list of considerations within each category were identified and, in some cases, relevant examples from existing state and federal geothermal regulations are included to further illustrate the proposed considerations. This report includes the following topics: 1) Geothermal Resource Definition; 2) Leasing process; 3) Exploration approval process; 4) Drilling/wellfield development approval process; 5) Underground injection control process In addition, a list of 'key considerations' summarized from this report are included below. This list is not meant to be exhaustive as each state's regulatory landscape is unique, rather these are meant to be concepts that can be considered when developing and/or updating existing geothermal regulations.
drilling↗
Sex Differences in Vagus Nerve Stimulation Effects on Rat Cardiovascular and Immune Systems
Background: Investigations into the benefits of vagus nerve stimulation (VNS) through pre-clinical and clinical research have led to promising findings for treating several disorders. Despite proven effectiveness of VNS on conditions such as epilepsy and depression, understanding of off-target effects and contributing factors such as sex differences can be beneficial to optimize therapy design. New Methods: In this article, we assessed longitudinal effects of VNS on cardiovascular and immune systems, and studied potential sex differences using a rat model of longterm VNS. Rats were implanted with cuff electrodes around the left cervical vagus nerve for VNS, and wireless physiological monitoring devices for continuous monitoring of cardiovascular system using electrocardiogram (ECG) signals. ECG morphology and heart rate variability (HRV) features were extracted to assess cardiovascular changes resulting from VNS in short-term and long-term timescales. We also assessed VNS effects on expression of inflammatory cytokines in blood during the course of the experiment. Statistical analysis was performed to compare results between Treatment and Sham groups, and between male and female animals from Treatment and Sham groups. Results: Considerable differences between male and female rats in cardiovascular effects of VNS were observed in multiple cardiovascular features. However, the effects seemed to be transient with approximately 1-h recovery after VNS. While short-term cardiovascular effects were mainly observed in male rats, females in general showed more significant long-term effects even after VNS stopped. We did not observe notable changes or sex differences in systemic cytokine levels resulting from VNS. Comparison With Existing Methods: Compared to existing methods, our study design incorporated wireless physiological monitoring and systemic blood cytokine level analysis, along with long-term VNS experiments in unanesthetized rats to study sex differences. Conclusion: The contribution of sex differences for long-term VNS off-target effects on cardiovascular and immune systems was assessed using awake behaving rats. Although VNS did not change the concentration of inflammatory biomarkers in systemic circulation for male and female rats, we observed significant differences in cardiovascular effects of VNS characterized using ECG morphology and HRV analyses.
59 BASIC BIOLOGICAL SCIENCES↗
Effect of Na Concentration on Cs Distribution with Crystalline Silicotitanate in Tank Waste Simulants
Crystalline silicotitanate (CST) ion exchange media is currently utilized in the tank side cesium removal (TSCR) system on the Hanford site to remove Cs-137 from the tank waste supernate. As the main dose contributor to the liquid supernate in Hanford tank waste, it is necessary to remove the Cs-137 to expedite low activity waste processing and immobilization. Ongoing batch contact experiments with CST have been done to tease out the impact of group II metals, anions, potassium, and temperature on Cs removal to better understand bounding conditions for operations as well as aid in development of a wholesome isotherm model to predict Cs behavior in the tank waste. This paper discusses the impact of Na concentration on Cs exchange and provides insight into the challenges associated with activity coefficient estimations for modeling Cs distribution in tank waste matrices.
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗
Quantifying Dam-Induced Fluctuations in Streamflow Frequencies Across the Colorado River Basin
Periodic fluctuations in natural streamflow are a major driver of river ecosystem dynamics and water resource management. However, most U.S. rivers are impacted both by long-term hydroclimatic trends and dams that alter flow variability. Despite these impacts, it remains largely unexplored how dams affect the dominant frequencies of natural streamflow over a highly regulated river network. We investigated the entire Colorado River Basin (CRB) to understand how the annual (10–14 months) and multi-annual (24–60 months) frequencies in natural flow regimes have been progressively altered by dams. Given the significant alteration over the CRB, we captured changes in streamflow frequencies between naturalized and observed monthly flows via wavelet analysis. Based on the similarity of changes in streamflow frequencies (annual and multi-annual) over the last 30 years, sections of the riverine network were classified into four groups. The annual frequency was relatively well preserved downstream of Hoover Dam, while showing a systematic trend of alteration downstream of Glen Canyon Dam until Hoover Dam. Meanwhile, the multi-annual frequency component was highly altered for the entire Lower Colorado main stem (i.e., downstream of Glen Canyon). We also identified dams with significant impacts on streamflow frequency by comparing wavelet coherence estimates. This study advances the notion that dams fundamentally alter river flow regimes across multiple frequencies and with varying amplitudes over time and space, with alteration propagating – or being dampened – by both hydroclimatic fluctuations and water resource management.
54 ENVIRONMENTAL SCIENCES↗
Ab initio lattice thermal conductivity of Mg Si O 3 across the perovskite-postperovskite phase transition
Lattice thermal conductivity (κ lat ) of MgSiO 3 postperovskite (MgPPv) under the Earth's lower mantle high pressure-temperature conditions is studied using the phonon quasiparticle approach by combing ab initio molecular dynamics and lattice dynamics simulations. Phonon lifetimes are extracted from the phonon quasiparticle calculations, and the phonon group velocities are computed from the anharmonic phonon dispersions, which, in principle, capture full anharmonicity. Here, it is found that throughout the lowermost mantle, including the D” region, κ lat of MgPPv is ~25% larger than that of MgSiO 3 perovskite (MgPv), mainly due to MgPPv's higher phonon velocities. Such a difference in phonon velocities between the two phases originates in the MgPPv's relatively smaller primitive cell. Systematic results of temperature and pressure dependences of both MgPPv's and MgPv's κ lat are demonstrated.
75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND↗
Raw electron microscopy images for "The Importance of Nano-edges in Atomic Stencilling and Chiroptically Active Assembly of Patchy Gold Tetrahedra"
This dataset contains the raw transmission electron microscopy (TEM) and scanning electron microscopy (SEM) images used in the main figures of the paper “The Importance of Nano-edges in Atomic Stencilling and Chiroptically Active Assembly of Patchy Gold Tetrahedra (2026).” All the images were acquired at the Materials Research Laboratory, University of Illinois at Urbana-Champaign, by Qian Chen group. 1. We provide five subfolders, each named according to the corresponding figure numbers in the paper. 2. All files in the subfolders for Figures 1–3 and 5 are named as "Panel [letter]_*", where [letter] (e.g., a, b, c) represents the raw images used for the corresponding panels. 3. All files in the subfolder for Figure 4 correspond to panel f and show the configurations of patchy tetrahedra synthesized at varying concentrations of iodide and 2-naphthalenethiol. They are named "Experiment_[number]", where [number] represents the corresponding data points in the phase diagram. 4. In TEM images, the bright and dark regions indicate the polymer patches and nanoparticle cores, respectively. 5. In SEM images, the bright and dark regions indicate the nanoparticle cores and polymer patches, respectively. 6. Abbreviations in file names: HAADF-STEM (high-angle annular dark-field scanning transmission electron microscopy), PINEM (photon-induced near-field electron microscopy), and RCP/LCP (left-/right-handed circularly polarized).
chirality↗
Building Envelope Campaign – Program Design and Stakeholder Engagement
Building envelope technologies impact approximately 30% of the primary energy consumed by residential and commercial buildings. The Building Envelope Campaign (BEC), which is part of the Department of Energy’s Better Buildings Program, is a market transformation effort to help building owners and managers invest in high performance building envelope technologies for both new and existing commercial buildings. The success of the Campaign has depended on constructing a compelling program design plus organizing a technical team with ability to effectively recruit Participants and Supporters from across industry and keep them engaged.The design of the campaign included developing a strategy to leverage other technology campaigns within the Better Buildings program, identifying stakeholders (including diverse member groups that may have been underserved by previous technology campaigns), recruiting Supporters and Participants, and providing technical assistance in the form of a campaign-specific Building Envelope Performance tool and metric to help benchmark various building envelope options.Engagement had to overcome three main challenges – securing the Campaign Supporters/Participants, helping participants to use the envelope tool to evaluate project options, and getting those participants to submit successful envelope projects for evaluation and recognition by the program. The concepts are simple but program design/implementation and, in particular, sustaining stakeholder engagement can be challenging. This paper will highlight the approaches taken in: program design, engaging industry members, identifying and reaching underserved stakeholders, demonstrating benefits of high performance building envelope technologies and making the case for engaging in this campaign.
McLeod, Hayley↗
Timing-Based Search for Magnetic Monopoles with the NOvA Detector on the Surface
We report a search for a magnetic monopole component of the cosmic-ray flux in a 2743-live-day exposure of the NOvA experiment's Far Detector, a 14 kt segmented liquid scintillator detector designed primarily to observe GeV-scale electron neutrinos. No events consistent with monopoles were observed, setting an upper limit on the flux of $8\times 10^{-16}~\mathrm{cm^{-2}s^{-1}sr^{-1}}$ at 90% C.L. for monopole speed $6\times 10^{-4} < β< 5\times 10^{-3}$ and mass greater than $10^{9}$ GeV. Because of NOvA's small overburden of 3 meters-water equivalent, this constraint covers a previously unexplored low-mass region.
Abubakar, S. [Erciyes U.]↗
Target space entanglement in Matrix Models
We study target space entanglement in gauged multi-matrix models as models of entanglement between groups of D-branes separated by a planar entangling surface, paying close attention to the implementation of gauge invariance. We open with a review of target space entanglement between identical particles, which shares some important features (specifically a gauged permutation symmetry) with our main problem. For our matrix models, we implement a gauge fixing well-adapted to the entangling surface. In this gauge, we map the matrix model problem to that of entanglement of a U(1) gauge theory on a complete or all-to-all lattice. Matrix elements corresponding to open strings stretching across the entangling surface in the target space lead to interesting contributions to the entanglement entropy.
71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗
Measurement of the $\bar ν_μ-$Hydrogen Charged-Current Quasi-Elastic Cross Section using the NOvA Near Detector
We report a measurement of the total cross section for muon antineutrino charged-current quasi-elastic scattering on hydrogen, $\bar ν_μ{\rm H} \to μ^+ n$, in the NOvA near detector using a $1.2\times10^{21}$ proton-on-target exposure in the NuMI beam. A selection based on topological and kinematic constraints yields 35,509 signal events in the hydrogen-rich ($10.8\%$) detector, providing the highest statistics of (anti)neutrino--hydrogen interactions measured to date. Backgrounds from (anti)neutrino interactions on heavier nuclei are constrained using dedicated data control samples, significantly reducing the related systematic uncertainties. We obtain a value $σ(\bar ν_μ{\rm H} \to μ^+ n) = 0.538 \pm 0.009 ({\rm stat}) \pm 0.010 ({\rm syst}) \pm0.055 ({\rm flux}) \times 10^{-38}$ cm$^2$ for the total cross section at an average energy of 1.9 GeV, the most precise total cross-section measurement of this process to date. The combined statistical and non-flux systematic uncertainty is more than four times smaller than the flux uncertainty, allowing a future use of this measurement to constrain the absolute $\bar ν_μ$ flux.
Abubakar, S. [Erciyes U.]↗
Measurement of the $\bar ν_μ-$Hydrogen Charged-Current Quasi-Elastic Cross Section using the NOvA Near Detector
We report a measurement of the total cross section for muon antineutrino charged-current quasi-elastic scattering on hydrogen, $\bar ν_μ{\rm H} \to μ^+ n$, in the NOvA near detector using a $1.2\times10^{21}$ proton-on-target exposure in the NuMI beam. A selection based on topological and kinematic constraints yields 35,509 signal events in the hydrogen-rich ($10.8\%$) detector, providing the highest statistics of (anti)neutrino--hydrogen interactions measured to date. Backgrounds from (anti)neutrino interactions on heavier nuclei are constrained using dedicated data control samples, significantly reducing the related systematic uncertainties. We obtain a value $σ(\bar ν_μ{\rm H} \to μ^+ n) = 0.538 \pm 0.009 ({\rm stat}) \pm 0.010 ({\rm syst}) \pm0.055 ({\rm flux}) \times 10^{-38}$ cm$^2$ for the total cross section at an average energy of 1.9 GeV, the most precise total cross-section measurement of this process to date. The combined statistical and non-flux systematic uncertainty is more than four times smaller than the flux uncertainty, allowing a future use of this measurement to constrain the absolute $\bar ν_μ$ flux.
Abubakar, S. [Erciyes U.]↗
Accuracy of Tau Positron Emission Tomography as a Prognostic Marker in Preclinical and Prodromal Alzheimer Disease: A Head-to-Head Comparison Against Amyloid Positron Emission Tomography and Magnetic Resonance Imaging
Importance: Tau positron emission tomography (PET) tracers have proven useful for the differential diagnosis of dementia, but their utility for predicting cognitive change is unclear. Objective: To examine the prognostic accuracy of baseline fluorine 18 ( 18 F)-flortaucipir and [18F]RO948 (tau) PET in individuals across the Alzheimer disease (AD) clinical spectrum and to perform a head-to-head comparison against established magnetic resonance imaging (MRI) and amyloid PET markers. Design, setting, and participants: This prognostic study collected data from 8 cohorts in South Korea, Sweden, and the US from June 1, 2014, to February 28, 2021, with a mean (SD) follow-up of 1.9 (0.8) years. A total of 1431 participants were recruited from memory clinics, clinical trials, or cohort studies; 673 were cognitively unimpaired (CU group; 253 [37.6%] positive for amyloid-β [Aβ]), 443 had mild cognitive impairment (MCI group; 271 [61.2%] positive for Aβ), and 315 had a clinical diagnosis of AD dementia (315 [100%] positive for Aβ). Exposures: [ 18 F]Flortaucipir PET in the discovery cohort (n = 1135) or [ 18 F]RO948 PET in the replication cohort (n = 296), T1-weighted MRI (n = 1431), and amyloid PET (n = 1329) at baseline and repeated Mini-Mental State Examination (MMSE) evaluation. Main outcomes and measures: Baseline [ 18 F]flortaucipir/[ 18 F]RO948 PET retention within a temporal region of interest, MRI-based AD-signature cortical thickness, and amyloid PET Centiloids were used to predict changes in MMSE using linear mixed-effects models adjusted for age, sex, education, and cohort. Mediation/interaction analyses tested whether associations between baseline tau PET and cognitive change were mediated by baseline MRI measures and whether age, sex, and APOE genotype modified these associations. Results: Among 1431 participants, the mean (SD) age was 71.2 (8.8) years; 751 (52.5%) were male. Findings for [ 18 F]flortaucipir PET predicted longitudinal changes in MMSE, and effect sizes were stronger than for AD-signature cortical thickness and amyloid PET across all participants (R 2 , 0.35 [tau PET] vs 0.24 [MRI] vs 0.17 [amyloid PET]; P < .001, bootstrapped for difference) in the Aβ-positive MCI group (R2, 0.25 [tau PET] vs 0.15 [MRI] vs 0.07 [amyloid PET]; P < .001, bootstrapped for difference) and in the Aβ-positive CU group (R 2 , 0.16 [tau PET] vs 0.08 [MRI] vs 0.08 [amyloid PET]; P < .001, bootstrapped for difference). These findings were replicated in the [ 18 F]RO948 PET cohort. MRI mediated the association between [ 18 F]flortaucipir PET and MMSE in the groups with AD dementia (33.4% [95% CI, 15.5%-60.0%] of the total effect) and Aβ-positive MCI (13.6% [95% CI, 0.0%-28.0%] of the total effect), but not the Aβ-positive CU group (3.7% [95% CI, -17.5% to 39.0%]; P = .71). Age (t = -2.28; P = .02), but not sex (t = 0.92; P = .36) or APOE genotype (t = 1.06; P = .29) modified the association between baseline [ 18 F]flortaucipir PET and cognitive change, such that older individuals showed faster cognitive decline at similar tau PET levels. Conclusions and relevance: The findings of this prognostic study suggest that tau PET is a promising tool for predicting cognitive change that is superior to amyloid PET and MRI and may support the prognostic process in preclinical and prodromal stages of AD.
59 BASIC BIOLOGICAL SCIENCES↗