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Muscle Deoxygenation Causes Muscle Fatigue

Muscle fatigue is a common musculoskeletal disorder in the work place, and may be a harbinger for more disabling cumulative trauma disorders. Although the cause of fatigue is multifactorial, reduced blood flow and muscle oxygenation may be the primary factor in causing muscle fatigue during low intensity muscle exertion. Muscle fatigue is defined as a reduction in muscle force production, and also occurs among astronauts who are subjected to postural constraints while performing lengthy, repetitive tasks. The objectives of this research are to: 1) develop an objective tool to study the role of decreased muscle oxygenation on muscle force production, and 2) to evaluate muscle fatigue during prolonged glovebox work.

Murthy, G.↗

Crew Factors in Flight Operations: A Survey of Fatigue Factors in Corporate/Executive A Viation Operations - 8

Corporate flight crews face unique challenges including unscheduled flights, quickly changing schedules, extended duty days, long waits, time zone changes, and peripheral tasks. Most corporate operations are regulated by Part 91 FARs which set no flight or duty time limits. The objective of this study was to identify operationally significant factors that may influence fatigue, alertness, and performance in corporate operations. In collaboration with the National Business Aircraft Association and the Flight Safety Foundation, NASA developed and distributed a retrospective survey comprising 107 questions addressing demographics, home sleep habits, flight experience, duty schedules, fatigue during operations, and work environment. Corporate crewmembers returned 1,488 surveys. Respondents averaged 45.2 years of age, had 14.9 years of corporate flying experience, and 9,750 total flight hours. The majority (89%) rated themselves as 'good' or 'very good' sleepers at home. Most (82%) indicated they are subject to call for duty and described an average duty day of 9.9 h. About two-thirds reported having a daily duty time limit and over half (57%) reported a daily flight time limit. Nearly three-quarters (71%) acknowledged having 'nodded off' during a flight. Only 21% reported that their flight departments offer training on fatigue issues. Almost three-quarters (74%) described fatigue as a 'moderate' or 'serious' concern, and a majority (61%) characterized it as a common occurrence. Most (85%) identified fatigue as a 'moderate' or 'serious' safety issue.

Rosekind, Mark R.↗

The Effect of Ballistic Impacts on the High Cycle Fatigue Properties of Ti-48Al-2Nb-2Cr (at.%)

The ability of gamma - TiAl to withstand potential foreign and/or domestic object damage is a technical risk to the implementation of gamma - TiAl in low pressure turbine (LPT) blade applications. The overall purpose of the present study was to determine the influence of ballistic impact damage on the high cycle fatigue strength of gamma - TiAl simulated LPT blades. Impact and specimen variables included ballistic impact energy, projectile hardness, impact temperature, impact location, and leading edge thickness. The level of damage induced by the ballistic impacting was studied and quantified on both the impact (front) and backside of the specimens. Multiple linear regression was used to model the cracking and fatigue response as a function of the impact variables. Of the impact variables studied, impact energy had the largest influence on the response of gamma - TiAl to ballistic impacting. Backside crack length was the best predictor of remnant fatigue strength for low energy impacts (<0.74J) whereas Hertzian crack length (impact side damage) was the best predictor for higher energy impacts. The impacted gamma - TiAl samples displayed a classical mean stress dependence on the fatigue strength. For the fatigue design stresses of a 6th stage LPT blade in a GE90 engine, a Ti-48Al-2Nb-2Cr LPT blade would survive an impact of normal service conditions.

Draper, S. L.↗

The Effect of O2, H2O, and N2 on the Fatigue Crack Growth Behavior of an Alpha + Beta Titanium Alloy at 24 C and 177 C

To study the effects of atmospheric species on the fatigue crack growth behavior of an a+B titanium alloy (Ti 6-2-2-2-2) at room temperature and 177 C, fatigue tests were performed in laboratory air, ultrahigh vacuum, and high purity water vapor, oxygen, nitrogen and helium at various partial pressures. Accelerated fatigue crack growth rates in laboratory air compared to ultrahigh vacuum are linked to the damaging effects of both water vapor and oxygen. Observations of the fatigue crack growth behavior in ultrahigh purity environments, along with surface film analysis using X-ray photoelectron spectroscopy (XPS), suggest that multiple crack-tip processes govern the damaging effects of air. Three possible mechanisms are proposed: 1) at low pressure (less than 10(exp -1) Pa), accelerated da/dN is likely due to monolayer adsorption on crack-tip surfaces presumably resulting in decreased bond strengths at the fatigue crack tip, 2) for pressures greater than 10(exp -1) Pa, accelerated da/dN in oxygen may result from oxidation at the crack tip limiting reversible slip, and 3) in water vapor, absorption of atomic hydrogen at the reactive crack tip resulting in process zone embrittlement.

Smith, Stephen W.↗

Research on the Effects of Fatigue within the Corporate/Business Aircraft Environment

In 1980, responding to a Congressional request, NASA Ames Research Center created a program to examine whether 'there is a safety problem of uncertain magnitude, due to transmeridian flying and a potential problem due to fatigue in association with various factors found in air transport operations.' The NASA Ames Fatigue/Jet Lag Program was created to collect systematic, scientific information on fatigue, sleep, circadian rhythms, and performance in flight operations. Three Program goals were established and continue to guide research efforts to: (1) determine the extent of fatigue, sleep loss, and circadian disruption in flight operations; (2) determine the impact of these factors on flight crew performance; (3) develop and evaluate countermeasures to mitigate the adverse effects of these factors and maximize flight crew performance and alertness. Since 1980, studies have been conducted in a variety of aviation environments, in controlled laboratory environments, as well as in a full-mission flight simulation. Early studies included investigations of short-haul, long-haul, and overnight cargo flight crews. In 1991, the name of the program was changed to the Fatigue Countermeasures Program to provide a greater emphasis on the development and evaluation of countermeasures. More recent work has examined the effects of planned cockpit rest as an operational countermeasure and provided analyses of the pertinent sleep/duty factors preceding an aviation accident at Guantanamo Bay, Cuba. The Short-Haul study examined the extent of sleep loss, circadian disruption, and fatigue engendered by flying commercial short-haul air transport operations (flight legs less than eight hours). This was one of the first field studies conducted by the NASA program and provided unique insight into the physiological and subjective effects of flying commercial short-haul operations. It demonstrated that a range of measures could be obtained in an operational environment without disturbing the regular performance of duties. The Long-Haul study examined how long-haul flight crews organized their sleep during a variety of international trip patterns and examined how duty requirements, local time, and the circadian system affected the timing, duration, and quality of sleep. Duty requirements and local time can be viewed as external/environmental constraints on time available for sleep, while the internal circadian system is a major physiological modulator of sleep duration and quality. The Overnight Cargo study documented the psychophysiological effects of flying overnight cargo operations. The data collected clearly demonstrated that overnight cargo operations, like other night work, involve physiological disruption not found in comparable daytime operations.

Neri, David F.↗

Influence Of Holes On The In-Plane Tensile Strength And Fatigue Durability Of A NICALON(Trademark)/Si-N-C Ceramic Matrix Composite

Effects of different sizes of holes as well as different percentages of open areas on the in-plane tensile strength and fatigue durability of the SiC/Si-N-C composite were investigated in this study. Test specimens with no holes, four different diameters of holes (1.0 to 3.2 mm), and four different open areas (20 to 35%) were machined. All mechanical testing was performed in air at a temperature of 910 C. Fatigue tests were conducted with a load ratio, R = 0.05, and a frequency of 0.33 Hz. In general, both the in-plane tensile strength of the composite and its fatigue durability decreased with an increase in the size of the hole and percentage of the open area. Reductions in the in-plane tensile strength and cyclic fatigue life of the composite were described by empirical equations with the diameter of the hole and the percent open area as the independent variables. The validity of these two empirical equations was verified with additional tensile and fatigue test data generated on the composite specimens.

Kalluri, Sreeramesh↗

Simulation of Fatigue Crack Initiation at Corrosion Pits With EDM Notches

Uniaxial fatigue tests were conducted to compare the fatigue life of laboratory produced corrosion pits, similar to those observed in the shuttle main landing gear wheel bolt-hole, and an electro-discharged-machined (EDM) flaw. EDM Jaws are used to simulate corrosion pits during shuttle wheel (dynamometer) testing. The aluminum alloy, (AA 7050) laboratory fatigue tests were conducted to simulate the local stress level contained in the wheel bolt-hole. Under this high local stress condition, the EDM notch produced a fatigue life similar to test specimens containing corrosion pits of similar size. Based on the laboratory fatigue test results, the EDM Jaw (semi-circular disc shaped) produces a local stress state similar to corrosion pits and can be used to simulate a corrosion pit during the shuttle wheel dynamometer tests.

Smith, Stephen W.↗

FLAPS (Fatigue Life Analysis Programs): Computer Programs to Predict Cyclic Life Using the Total Strain Version of Strainrange Partitioning and Other Life Prediction Methods

This manual presents computer programs FLAPS for characterizing and predicting fatigue and creep-fatigue resistance of metallic materials in the high-temperature, long-life regime for isothermal and nonisothermal fatigue. The programs use the Total Strain version of Strainrange Partitioning (TS-SRP), and several other life prediction methods described in this manual. The user should be thoroughly familiar with the TS-SRP and these life prediction methods before attempting to use any of these programs. Improper understanding can lead to incorrect use of the method and erroneous life predictions. An extensive database has also been developed in a parallel effort. The database is probably the largest source of high-temperature, creep-fatigue test data available in the public domain and can be used with other life-prediction methods as well. This users' manual, software, and database are all in the public domain and can be obtained by contacting the author. The Compact Disk (CD) accompanying this manual contains an executable file for the FLAPS program, two datasets required for the example problems in the manual, and the creep-fatigue data in a format compatible with these programs.

Arya, Vinod K.↗

Work and fatigue characteristics of unsuited and suited humans during isolated isokinetic joint motions

The effects of a pressurized suit on human performance were investigated. The suit is known as an Extra-Vehicular Mobility Unit (EMU) and is worn by astronauts while working outside their spacecraft in a low earth orbit. Isolated isokinetic joint torques of three female and three male subjects (all experienced users of the suit in 1G gravity) were measured while working at 100% and 80% of their maximum voluntary torque (MVT, which is synonymous with maximum voluntary contraction (MVC)). It was found that the average decrease in the total amount of work (the sum of the work in each repetition until fatigue) done when the subjects were wearing the EMU were 48% and 41% while working at 100% and 80% MVT, respectively. There is a clear relationship between the MVT and the time and amount of work done until fatigue. Here, the time to fatigue is defined as the ending time of the repetition for which the computed work done during that repetition dropped below 50% of the work done during the first repetition. In general the stronger joints took longer to fatigue and did more work than the weaker joints. It was found that the EMU decreases the work output at the wrist and shoulder joints the most, due to the EMU joint geometry. The EMU also decreased the joint range of motion. The average total amount of work done by the test subjects increased by 5.2% (20.4%) for the unsuited (suited) case, when the test subjects decreased the level of effort from 100% to 80% MVT. Also, the average time to fatigue increased by 9.2% (25.6%) for the unsuited (suited) case, when the test subjects decreased the level of effort from 100% to 80% MVT. It was also found that the experimentally measured torque decay could be predicted by a logarithmic equation. The absolute average errors in the predictions were found to be 18.3% and 18.9% for the unsuited and suited subjects, respectively, when working at 100% MVT, and 22.5% and 18.8% for the unsuited and suited subjects, respectively, when working at 80% MVT. These results could be very useful in the design of future EMU suits and the planning of Extra-Vehicular Activity (EVA) for the future International Space Station assembly operations.

NASA Discipline Life Sciences Technologies↗

Comparison of Mode II and III Monotonic and Fatigue Delamination Onset Behavior for Carbon/Toughened Epoxy Composites

Monotonic and fatigue tests were performed to compare the Mode II and III interlaminar fracture toughness and fatigue delamination onset for Tenax-HTA/R6376 carbon/toughened epoxy composites. The Mode II interlaminar fracture toughness and fatigue delamination onset were characterized using the end-notched flexure (ENF) test while the Mode III interlaminar fracture toughness and fatigue delamination onset were characterized by using the edge crack torsion (ECT) test. Monotonic tests show that the Mode III fracture toughness is higher than the Mode II fracture toughness. Both Mode II and III cyclic loading greatly increases the tendency for a delamination to grow relative to a single monotonically increasing load. Under fatigue loading, the Mode III specimen also has a longer life than the Mode II specimen.

Li, Jian↗

Effect of Surface Impulsive Thermal Loads on Fatigue Behavior of Constant Volume Propulsion Engine Combustor Materials

The development of advanced high performance constant-volume-combustion-cycle engines (CVCCE) requires robust design of the engine components that are capable of enduring harsh combustion environments under high frequency thermal and mechanical fatigue conditions. In this study, a simulated engine test rig has been established to evaluate thermal fatigue behavior of a candidate engine combustor material, Haynes 188, under superimposed CO2 laser surface impulsive thermal loads (30 to 100 Hz) in conjunction with the mechanical fatigue loads (10 Hz). The mechanical high cycle fatigue (HCF) testing of some laser pre-exposed specimens has also been conducted under a frequency of 100 Hz to determine the laser surface damage effect. The test results have indicated that material surface oxidation and creep-enhanced fatigue is an important mechanism for the surface crack initiation and propagation under the simulated CVCCE engine conditions.

Zhu, Dongming↗

Effects of High Temperature Exposures on Fatigue Life of Disk Superalloys

The effects on fatigue life of high temperature exposures simulating service conditions were considered for two disk superalloys. Powder metallurgy processed, supersolvus heat treated Udimet (trademark) 720 and ME3 fatigue specimens were exposed in air at temperatures of 650 to 704 C, for times of 100 h to over 1000 h. They were then tested using conventional fatigue tests at 650 and 704 C, to determine the effects of exposure on fatigue resistance. Cyclic dwell verification tests were also performed to contrast the effects of intermixed exposures and fatigue cycles. The prior exposures reduced life by up to 70% and increased the scatter in life, compared to unexposed levels. Cyclic dwell tests reduced lives even more. Fractographic evaluations indicated the failure mode was shifted by the exposures and cyclic dwells from predominantly internal to often surface crack initiations. The increased scatter in life was related to the competition between internal crack initiations at inclusions or large grains producing longer lives, and surface crack initiations at an environmentally affected surface layer producing shorter lives.

Gabb, Tim P.↗

Application of Self Nulling Eddy Current Probe Technique to the Detection of Fatigue Crack Initiation and Control of Test Procedures

A major part of fracture mechanics is concerned with studying the initiation and propagation of fatigue cracks. This typically requires constant monitoring of crack growth during fatigue cycles and the knowledge of the precise location of the crack tip at any given time. One technique currently available for measuring fatigue crack length is the Potential Drop method. The method, however, may be inaccurate if the direction of crack growth deviates considerably from what was assumed initially or the curvature of the crack becomes significant. Another popular approach is to optically view the crack using a high magnification microscope, but this entails a person constantly monitoring it. The present proposed technique uses an automated scheme, in order to eliminate the need for a person to constantly monitor the experiment. Another technique under development elsewhere is to digitize an optical image of the test specimen surface and then apply a pattern recognition algorithm to locate the crack tip. A previous publication showed that the self nulling eddy current probe successfully tracked a simulated crack in an aluminum sample. This was the impetus to develop an online real time crack monitoring system. An automated system has been developed which includes a two axis scanner mounted on the tensile testing machine, the probe and its instrumentation and a personal computer (PC) to communicate and control all the parameters. The system software controls the testing parameters as well as monitoring the fatigue crack as it propagates. This paper will discuss the experimental setup in detail and demonstrate its capabilities. A three dimensional finite element model is utilized to model the magnetic field distribution due to the probe and how the probe voltage changes as it scans the crack. Experimental data of the probe for different samples under zero load, static load and high cycle fatigue load will be discussed. The final section summarizes the major accomplishments of the present work, the elements of the future R&D needs and the advantages and disadvantages of using this system in the laboratory and field.

Namkung, M.↗

An Application of a New Electromagnetic Sensor to Real-Time Monitoring of Fatigue Crack Growth in Thin Metal Plates

A major part of fracture mechanics is concerned with studying the initiation and propagation of fatigue cracks. This typically requires constant monitoring of crack growth during fatigue cycles which necessitates automation of the whole process. If the rate of crack growth can be determined the experimenter can vary externally controlled parameters such as load level, load cycle frequency and so on. Hence, knowledge of the precise location of the crack tip at any given time is very valuable. One technique currently available for measuring fatigue crack length is the DC potential drop method. The method, however, may be inaccurate if the direction of crack growth deviates considerably from what was assumed initially or the curvature of the crack becomes significant. Another approach is to digitize an optical image of the test specimen surface and then apply a pattern recognition technique to locate the crack tip, but this method is still under development. The present work is an initial study on applying eddy current-type probes to monitoring fatigue crack growth. The performance of two types of electromagnetic probes, a conventional eddy current probe and a newly developed self-nulling probe, was evaluated for the detection characteristics at and near the tips of fatigue cracks. The scan results show that the latter probe provides a very well defined local maximum in its output in the crack tip region suggesting the definite possibility of precisely locating the tip, while the former provides a somewhat ambiguous distribution of the sensor output in the same region. The paper is organized as follows: We start by reviewing the design and performance characteristics of the self-nulling probe and then describe the scan results which demonstrate the basic properties of the self-nulling probe. Next, we provide a brief description of the software developed for tracing a simulated crack and give a brief discussion of the main results of the test. The final section summarizes the major accomplishments of the present work and the elements of the future R&D needs.

Namkung, M.↗

Muscle fatigue in frog semitendinosus: alterations in contractile function

The purpose of this study was to characterize the contractile properties of the frog semitendinosus (ST) muscle before and during recovery from fatigue, to relate the observed functional changes to alterations in specific steps in the crossbridge model of muscle contraction, and to determine how fatigue affects the force-frequency relationship. The frog ST (22 degrees C) was fatigued by direct electrical stimulation with 100-ms 150-Hz trains at 1/s for 5 min. The fatigue protocol reduced peak twitch (Pt) and tetanic (Po) force to 32 and 8.5% of initial force, respectively. The decline in Pt was less than Po, in part due to a prolongation in the isometric contraction time (CT), which increased to 300% of the initial value. The isometric twitch duration was greatly prolonged as reflected by the lengthened CT and the 800% increase in the one-half relaxation time (1/2RT). Both Pt and Po showed a biphasic recovery, a rapid initial phase (2 min) followed by a slower (40 min) return to the prefatigue force. CT and 1/2RT also recovered in two phases, returning to 160 and 265% of control in the first 5 min. CT returned to the prefatigue value between 35 and 40 min, whereas even at 60 min 1/2RT was 133% of control. The maximal velocity of shortening, determined by the slack test, was significantly reduced [from 6.7 +/- 0.5 to 2.5 +/- 0.4 optimal muscle length/s] at fatigue. The force-frequency relationship was shifted to the left, so that optimal frequency for generating Po was reduced.(ABSTRACT TRUNCATED AT 250 WORDS).

NASA Discipline Musculoskeletal↗

Fatigue mechanisms in patients with cancer: effects of tumor necrosis factor and exercise on skeletal muscle

Fatigue is a common adverse effect of cancer and its therapy. However, the specific mechanisms underlying cancer fatigue are unclear. One physiologic mechanism may involve changes in skeletal muscle protein stores or metabolite concentration. A reduction in skeletal muscle protein stores may result from endogenous tumor necrosis factor (TNF) or from TNF administered as antineoplastic therapy. This muscle wasting would require patients to exert an unusually high amount of effort to generate adequate contractile force during exercise performance or during extended periods of sitting or standing. This additional effort could result in the onset of fatigue. Additionally, cancer fatigue may develop or become exacerbated during exercise as a consequence of changes in the concentration of skeletal muscle metabolites. These biochemical alterations may interfere with force that is produced by the muscle contractile proteins. These physiologic changes may play a role in the decision to include exercise in the rehabilitation plans of patients with cancer. They also may affect ideas about fatigue.

Review, Tutorial↗

Effectiveness of Shot Peening in Suppressing Fatigue Cracking at Non-Metallic Inclusions in Udimet(trademark) 720

The fatigue lives of modern powder metallurgy disk alloys can be reduced by over an order of magnitude by surface cracking at inherent non-metallic inclusions. The objective of this work was to study the effectiveness of shot peening in suppressing LCF crack initiation and growth at surface nonmetallic inclusions. Inclusions were carefully introduced at elevated levels during powder metallurgy processing of the nickel-base disk superalloy Udimet 720. Multiple strain-controlled fatigue tests were then performed on machined specimens at 427 and 650 C in peened and unpeened conditions. Analyses were performed to compare the low cycle fatigue lives and failure initiation sites as a function of inclusion content, shot peening, and fatigue conditions. A large majority of the failures in as-machined specimens with introduced inclusions occurred at cracks initiating from inclusions intersecting the specimen surface. The inclusions could reduce fatigue life by up to 100X. Large inclusions had the greatest effect on life in tests at low strain ranges and high strain ratios. Shot peening can be used to improve life in these conditions by reducing the most severe effects of inclusions.

Barrie, Robert L.↗

Comparison of the Fatigue Behavior of Copper Alloys

This presentation is about the development of advanced copper alloys with high thermal conductivity, good creep strength, and adequate fatigue strength for rocket engine applications. It also focuses on the commercial availability of the advanced alloy-GRCop-84 developed at NASA-GRC. The presentation's conclusions are that GRCop-84 has equivalent or better isothermal fatigue lives compared to other commercially available copper alloys, that GRCop-84 can be fabricated in various forms with minimal change in the fatigue lives, that it is equivalent in sothermal, fatigue to AMZIRC at moderate temperatures, and that Narloy-Z is equivalent in fatigue capabilities to GRCop-84 at 400C and below.

Lerch, Brad↗