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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 361 records · Page 20

Neutrophil to Lymphocyte Ratio: A Prognostic Indicator for Astronaut Health

Short-term and long-term spaceflight missions can cause immune system dysfunction in astronauts. Recent studies indicate elevated white blood cells (WBC) and polymorphonuclear neutrophils (PMN) in astronaut blood, along with unchanged or reduced lymphocyte counts, and reduced T cell function, during short-(days) and long-(months) term spaceflight. A high PMN to lymphocyte ratio (NLR) can acts as a strong predictor of poor prognosis in cancer, and as a biomarker for subclinical inflammation in humans and chronic stress in mouse models, however, the NLR has not yet been identified as a predictor of astronaut health during spaceflight. For this, complete blood cell count data collected from astronauts and rodents that have flown for short- and long-term missions on board the International Space Station (ISS) was repurposed to determine the NLR pre-, in-, and post-flight. The results displayed that the NLR progressively increased during spaceflight in both human and mice, while a spike in the NLR was observed at post-flight landing, suggesting stress-induced factors may be involved. In addition, the ground-based chronic microgravity analog, hindlimb unloading in mice, indicated an increased NLR, along with induced myeloperoxidase expression, as measured by quantitative (q)PCR. The mechanism for increased NLR was further assessed in vitro using the NASA-developed rotating wall vessel (RWV) cell culture suspension system with human WBCs. The results indicated that simulated microgravity led to increased mature PMN counts, NLR profiles, and production of reactive oxygen species (ROS). Collectively, these studies show that an increased NLR is observed in spaceflight missions, and in chronic microgravity-analog simulation in mice, and that this effect may be potentiated by the oxidative stress response in blood cells under microgravity conditions. Furthermore, these results suggest that a disrupted NLR profile in spaceflight may further disrupt immune homeostasis, potentially causing chronic immune-mediated inflammatory diseases. Thus, we propose that the health status of astronauts during short- and long-term space missions can be monitored by their NLR profile, in addition to utilizing this measurement as a tool for interventions and countermeasure development to restore homeostatic immunity.

biomarker↗

Earth Global Reference Atmospheric Model 2007 (Earth-GRAM07)

GRAM is a Fortran software package that can run on a variety of platforms including PC's. GRAM provides values of atmospheric quantities such as temperature, pressure, density, winds, constituents, etc. GRAM99 covers all global locations, all months, and heights from the surface to approx. 1000 km). Dispersions (perturbations) of these parameters are also provided and are spatially and temporally correlated. GRAM can be run in a stand-alone mode or called as a subroutine from a trajectory program. GRAM07 is diagnostic, not prognostic (i.e., it describes the atmosphere, but it does not forecast). The source code is distributed free-of-charge to eligible recipients.

Leslie, Fred W.↗

Prognostics of Power MOSFET

This paper demonstrates how to apply prognostics to power MOSFETs (metal oxide field effect transistor). The methodology uses thermal cycling to age devices and Gaussian process regression to perform prognostics. The approach is validated with experiments on 100V power MOSFETs. The failure mechanism for the stress conditions is determined to be die-attachment degradation. Change in ON-state resistance is used as a precursor of failure due to its dependence on junction temperature. The experimental data is augmented with a finite element analysis simulation that is based on a two-transistor model. The simulation assists in the interpretation of the degradation phenomena and SOA (safe operation area) change.

Celaya, Jose Ramon↗

Technical report series on global modeling and data assimilation. Volume 6: A multiyear assimilation with the GEOS-1 system: Overview and results

The Data Assimilation Office (DAO) at Goddard Space Flight Center has produced a multiyear global assimilated data set with version 1 of the Goddard Earth Observing System Data Assimilation System (GEOS-1 DAS). One of the main goals of this project, in addition to benchmarking the GEOS-1 system, was to produce a research quality data set suitable for the study of short-term climate variability. The output, which is global and gridded, includes all prognostic fields and a large number of diagnostic quantities such as precipitation, latent heating, and surface fluxes. Output is provided four times daily with selected quantities available eight times per day. Information about the observations input to the GEOS-1 DAS is provided in terms of maps of spatial coverage, bar graphs of data counts, and tables of all time periods with significant data gaps. The purpose of this document is to serve as a users' guide to NASA's first multiyear assimilated data set and to provide an early look at the quality of the output. Documentation is provided on all the data archives, including sample read programs and methods of data access. Extensive comparisons are made with the corresponding operational European Center for Medium-Range Weather Forecasts analyses, as well as various in situ and satellite observations. This document is also intended to alert users of the data about potential limitations of assimilated data, in general, and the GEOS-1 data, in particular. Results are presented for the period March 1985-February 1990.

Suarez, Max J.↗

A Finite-Volume "Shaving" Method for Interfacing NASA/DAO''s Physical Space Statistical Analysis System to the Finite-Volume GCM with a Lagrangian Control-Volume Vertical Coordinate

Toward the development of a finite-volume Data Assimilation System (fvDAS), a consistent finite-volume methodology is developed for interfacing the NASA/DAO's Physical Space Statistical Analysis System (PSAS) to the joint NASA/NCAR finite volume CCM3 (fvCCM3). To take advantage of the Lagrangian control-volume vertical coordinate of the fvCCM3, a novel "shaving" method is applied to the lowest few model layers to reflect the surface pressure changes as implied by the final analysis. Analysis increments (from PSAS) to the upper air variables are then consistently put onto the Lagrangian layers as adjustments to the volume-mean quantities during the analysis cycle. This approach is demonstrated to be superior to the conventional method of using independently computed "tendency terms" for surface pressure and upper air prognostic variables.

Lin, Shian-Jiann↗

Hybrid Modeling for Complex Systems Health Management

The research work presents application of hybrid physics-informed machine learning to a representative electric powertrain for unmanned aerial vehicles. The model is composed of physics-derived and empirical equations, integrated with connected networks that are strategically placed within the model to substitute equations that are subject to large uncertainty. Polynomial fit driven by heuristics or empirical observations can be substituted by more flexible networks that can minimize the error between model predictions and observations without being restricted to a predefined functional form. This modeling strategy allows training of networks deep inside the model and unknown parameters in a single learning stage. The powertrain model consists of Li-ion batteries, electronic speed controller with pulse-width modulation, and brush-less DC motor with connected propeller. Results obtained from combination of laboratory and simulation tests are discussed in this work.

PINNS↗

Outlook towards deployable continual learning for particle accelerators

Particle accelerators are high power complex machines. To ensure uninterrupted operation of these machines, thousands of pieces of equipment need to be synchronized, which requires addressing many challenges including design, optimization and control, anomaly detection and machine protection. With recent advancements, machine learning (ML) holds promise to assist in more advance prognostics, optimization, and control. While ML based solutions have been developed for several applications in particle accelerators, only few have reached deployment and even fewer to long term usage, due to particle accelerator data distribution drifts caused by changes in both measurable and non-measurable parameters. In this paper, we identify some of the key areas within particle accelerators where continual learning can allow maintenance of ML model performance with distribution drifts. Particularly, we first discuss existing applications of ML in particle accelerators, and their limitations due to distribution drift. Next, we review existing continual learning techniques and investigate their potential applications to address data distribution drifts in accelerators. By identifying the opportunities and challenges in applying continual learning, this paper seeks to open up the new field and inspire more research efforts towards deployable continual learning for particle accelerators.

43 PARTICLE ACCELERATORS↗

A brief description of the simple biosphere model (SiB)

A biosphere model for calculating the transfer of energy, mass, and momentum between the atmosphere and the vegetated surface of the Earth was designed for atmospheric general circulation models. An upper vegetation layer represents the perennial canopy of trees or shrubs, a lower layer represents the annual ground cover of grasses and other herbacious species. The local coverage of each vegetation layer may be fractional or complete but as the individual vegetation elements are considered to be evenly spaced, their root systems are assumed to extend uniformly throughout the entire grid-area. The biosphere has seven prognostic physical-state variables: two temperatures (one for the canopy and one for the ground cover and soil surface); two interception water stores (one for the canopy and one for the ground cover); and three soil moisture stores (two of which can be reached by the vegetation root systems and one underlying recharge layer into and out of which moisture is transferred only by hydraulic diffusion).

Sellers, P. J.↗

Tau Positron Emission Tomography for Predicting Dementia in Individuals With Mild Cognitive Impairment

An accurate prognosis is especially pertinent in mild cognitive impairment (MCI), when individuals experience considerable uncertainty about future progression. To evaluate the prognostic value of tau positron emission tomography (PET) to predict clinical progression from MCI to dementia. This was a multicenter cohort study with external validation and a mean (SD) follow-up of 2.0 (1.1) years. Data were collected from centers in South Korea, Sweden, the US, and Switzerland from June 2014 to January 2024. Participant data were retrospectively collected and inclusion criteria were a baseline clinical diagnosis of MCI; longitudinal clinical follow-up; a Mini-Mental State Examination (MMSE) score greater than 22; and available tau PET, amyloid-β (Aβ) PET, and magnetic resonance imaging (MRI) scan less than 1 year from diagnosis. A total of 448 eligible individuals with MCI were included (331 in the discovery cohort and 117 in the validation cohort). None of these participants were excluded over the course of the study. Exposures included Tau PET, Aβ PET, and MRI. Positive results on tau PET (temporal meta–region of interest), Aβ PET (global; expressed in the standardized metric Centiloids), and MRI (Alzheimer disease [AD] signature region) was assessed using quantitative thresholds and visual reads. Clinical progression from MCI to all-cause dementia (regardless of suspected etiology) or to AD dementia (AD as suspected etiology) served as the primary outcomes. The primary analyses were receiver operating characteristics. In the discovery cohort, the mean (SD) age was 70.9 (8.5) years, 191 (58%) were male, the mean (SD) MMSE score was 27.1 (1.9), and 110 individuals with MCI (33%) converted to dementia (71 to AD dementia). Only the model with tau PET predicted all-cause dementia (area under the receiver operating characteristic curve [AUC], 0.75; 95% CI, 0.70-0.80) better than a base model including age, sex, education, and MMSE score (AUC, 0.71; 95% CI, 0.65-0.77; P = .02), while the models assessing the other neuroimaging markers did not improve prediction. In the validation cohort, tau PET replicated in predicting all-cause dementia. Compared to the base model (AUC, 0.75; 95% CI, 0.69-0.82), prediction of AD dementia in the discovery cohort was significantly improved by including tau PET (AUC, 0.84; 95% CI, 0.79-0.89; P < .001), tau PET visual read (AUC, 0.83; 95% CI, 0.78-0.88; P = .001), and Aβ PET Centiloids (AUC, 0.83; 95% CI, 0.78-0.88; P = .03). In the validation cohort, only the tau PET and the tau PET visual reads replicated in predicting AD dementia. In this study, tau-PET showed the best performance as a stand-alone marker to predict progression to dementia among individuals with MCI. This suggests that, for prognostic purposes in MCI, a tau PET scan may be the best currently available neuroimaging marker.

59 BASIC BIOLOGICAL SCIENCES↗

Software Testbed for Developing and Evaluating Integrated Autonomous Subsystems

To implement fault tolerant autonomy in future space systems, it will be necessary to integrate planning, adaptive control, and state estimation subsystems. However, integrating these subsystems is difficult, time-consuming, and error-prone. This paper describes Intelliface/ADAPT, a software testbed that helps researchers develop and test alternative strategies for integrating planning, execution, and diagnosis subsystems more quickly and easily. The testbed's architecture, graphical data displays, and implementations of the integrated subsystems support easy plug and play of alternate components to support research and development in fault-tolerant control of autonomous vehicles and operations support systems. Intelliface/ADAPT controls NASA's Advanced Diagnostics and Prognostics Testbed (ADAPT), which comprises batteries, electrical loads (fans, pumps, and lights), relays, circuit breakers, invertors, and sensors. During plan execution, an experimentor can inject faults into the ADAPT testbed by tripping circuit breakers, changing fan speed settings, and closing valves to restrict fluid flow. The diagnostic subsystem, based on NASA's Hybrid Diagnosis Engine (HyDE), detects and isolates these faults to determine the new state of the plant, ADAPT. Intelliface/ADAPT then updates its model of the ADAPT system's resources and determines whether the current plan can be executed using the reduced resources. If not, the planning subsystem generates a new plan that reschedules tasks, reconfigures ADAPT, and reassigns the use of ADAPT resources as needed to work around the fault. The resource model, planning domain model, and planning goals are expressed using NASA's Action Notation Modeling Language (ANML). Parts of the ANML model are generated automatically, and other parts are constructed by hand using the Planning Model Integrated Development Environment, a visual Eclipse-based IDE that accelerates ANML model development. Because native ANML planners are currently under development and not yet sufficiently capable, the ANML model is translated into the New Domain Definition Language (NDDL) and sent to NASA's EUROPA planning system for plan generation. The adaptive controller executes the new plan, using augmented, hierarchical finite state machines to select and sequence actions based on the state of the ADAPT system. Real-time sensor data, commands, and plans are displayed in information-dense arrays of timelines and graphs that zoom and scroll in unison. A dynamic schematic display uses color to show the real-time fault state and utilization of the system components and resources. An execution manager coordinates the activities of the other subsystems. The subsystems are integrated using the Internet Communications Engine (ICE). an object-oriented toolkit for building distributed applications.

Testbed↗

Toward a Turbulence Constitutive Relation for Rotating Flows

In rapidly rotating turbulent flows the largest scales of the motion are in approximate geostrophic balance. Single-point turbulence closures, in general, cannot attain a geostrophic balance. This article addresses and resolves the possibility of constitutive relation procedures for single-point second order closures for a specific class of rotating or stratified flows. Physical situations in which the geostrophic balance is attained are described. Closely related issues of frame-indifference, horizontal nondivergence, Taylor-Proudman theorem and two-dimensionality are, in the context of both the instantaneous and averaged equations, discussed. It is shown, in the absence of vortex stretching along the axis of rotation, that turbulence is frame-indifferent. A derivation and discussion of a geostrophic constraint which the prognostic equations for second-order statistics must satisfy for turbulence approaching a frame-indifferent limit is given. These flow situations, which include rotating and nonrotating stratified flows, are slowly evolving flows in which the constitutive relation procedures are useful. A nonlinear non-constant coefficient representation for the rapid-pressure strain covariance appearing in the Reynolds stress and heat flux equations consistent with the geostrophic balance is described. The rapid-pressure strain model coefficients are not constants determined by numerical optimization but are functions of the state of the turbulence as parameterized by the Reynolds stresses and the turbulent heat fluxes. The functions are valid for all states of the turbulence attaining their limiting values only when a limit state is achieved. These issues are relevant to strongly vortical flows as well as flows such as the planetary boundary layers, in which there is a transition from a three-dimensional shear driven turbulence to a geostrophic or horizontal turbulence.

Ristorcelli, J. R.↗

End-of-Discharge and End-of-Life Prediction in Lithium-Ion Batteries with Electrochemistry-Based Aging Models

As batteries become increasingly prevalent in complex systems such as aircraft and electric cars, monitoring and predicting battery state of charge and state of health becomes critical. In order to accurately predict the remaining battery power to support system operations for informed operational decision-making, age-dependent changes in dynamics must be accounted for. Using an electrochemistry-based model, we investigate how key parameters of the battery change as aging occurs, and develop models to describe aging through these key parameters. Using these models, we demonstrate how we can (i) accurately predict end-of-discharge for aged batteries, and (ii) predict the end-of-life of a battery as a function of anticipated usage. The approach is validated through an experimental set of randomized discharge profiles.

batteries↗

Errant Beam Prognostics with Machine Leaning at SNS Accelerator

Particle Accelerators are complex machine with many pieces of equipment running in synchronization to deliver required beam. However, faults in particle accelerators reduce the availability of the beam for experiments affecting the overall science output. To avoid these faults, we apply anomaly detection techniques to predict any unusual behavior and perform preemptive actions to improve the total availability. Many researchers have adopted semi-supervised Machine Learning (ML) methods such as auto-encoders and variational auto-encoders for such tasks. However, supervised ML techniques designed for similarity learning such as Siamese Neural Network (SNN) can outperform semi-supervised or unsupervised methods for anomaly prediction. One of the challenges associated with application of ML models to particle accelerators is the variability in observed data over time due to system configuration changes. We employ conditional models such as Conditional Siamese Neural Networks (CSNN), and Conditional-VAE (CVAE) to learn the variability in the data by using beam configuration parameters as conditional input. We apply these models for errant beam prediction at Spallation Neutron Source accelerator under different system configurations and compare their performance. We demonstrate that CSNN outperforms CVAE in our application. This talk will present the data source, collection, analysis, data-preparation, model development, hyper-parameter studies and the results.

Rajput, Kishansingh↗

Benchmarking Diagnostic Algorithms on an Electrical Power System Testbed

Diagnostic algorithms (DAs) are key to enabling automated health management. These algorithms are designed to detect and isolate anomalies of either a component or the whole system based on observations received from sensors. In recent years a wide range of algorithms, both model-based and data-driven, have been developed to increase autonomy and improve system reliability and affordability. However, the lack of support to perform systematic benchmarking of these algorithms continues to create barriers for effective development and deployment of diagnostic technologies. In this paper, we present our efforts to benchmark a set of DAs on a common platform using a framework that was developed to evaluate and compare various performance metrics for diagnostic technologies. The diagnosed system is an electrical power system, namely the Advanced Diagnostics and Prognostics Testbed (ADAPT) developed and located at the NASA Ames Research Center. The paper presents the fundamentals of the benchmarking framework, the ADAPT system, description of faults and data sets, the metrics used for evaluation, and an in-depth analysis of benchmarking results obtained from testing ten diagnostic algorithms on the ADAPT electrical power system testbed.

Kurtoglu, Tolga↗

Intelligent Vehicle Health Management

As a part of the overall goal of developing Integrated Vehicle Health Management systems for aerospace vehicles, the NASA Faculty Fellowship Program (NFFP) at Marshall Space Flight Center has performed a pilot study on IVHM principals which integrates researched IVHM technologies in support of Integrated Intelligent Vehicle Management (IIVM). IVHM is the process of assessing, preserving, and restoring system functionality across flight and ground systems (NASA NGLT 2004). The framework presented in this paper integrates advanced computational techniques with sensor and communication technologies for spacecraft that can generate responses through detection, diagnosis, reasoning, and adapt to system faults in support of INM. These real-time responses allow the IIVM to modify the affected vehicle subsystem(s) prior to a catastrophic event. Furthermore, the objective of this pilot program is to develop and integrate technologies which can provide a continuous, intelligent, and adaptive health state of a vehicle and use this information to improve safety and reduce costs of operations. Recent investments in avionics, health management, and controls have been directed towards IIVM. As this concept has matured, it has become clear the INM requires the same sensors and processing capabilities as the real-time avionics functions to support diagnosis of subsystem problems. New sensors have been proposed, in addition, to augment the avionics sensors to support better system monitoring and diagnostics. As the designs have been considered, a synergy has been realized where the real-time avionics can utilize sensors proposed for diagnostics and prognostics to make better real-time decisions in response to detected failures. IIVM provides for a single system allowing modularity of functions and hardware across the vehicle. The framework that supports IIVM consists of 11 major on-board functions necessary to fully manage a space vehicle maintaining crew safety and mission objectives: Guidance and Navigation; Communications and Tracking; Vehicle Monitoring; Information Transport and Integration; Vehicle Diagnostics; Vehicle Prognostics; Vehicle mission Planning; Automated Repair and Replacement; Vehicle Control; Human Computer Interface; and Onboard Verification and Validation. Furthermore, the presented framework provides complete vehicle management which not only allows for increased crew safety and mission success through new intelligence capabilities, but also yields a mechanism for more efficient vehicle operations. The representative IVHM technologies for computer platform using heterogeneous communication, 3) coupled electromagnetic oscillators for enhanced communications, 4) Linux-based real-time systems, 5) genetic algorithms, 6) Bayesian Networks, 7) evolutionary algorithms, 8) dynamic systems control modeling, and 9) advanced sensing capabilities. This paper presents IVHM technologies developed under NASA's NFFP pilot project and the integration of these technologies forms the framework for IIVM.

Paris, Deidre E.↗

Data Assimilation of Terrestrial Water Storage Observations to Estimate Precipitation Fluxes: A Synthetic Experiment

The Gravity Recovery and Climate Experiment (GRACE) mission and its Follow-On (GRACE-FO) mission provide unprecedented observations of terrestrial water storage (TWS) dynamics at basin to continental scales. Established GRACE data assimilation techniques directly adjust the simulated water storage components to improve the estimation of groundwater, streamflow, and snow water equivalent. Such techniques artificially add/subtract water to/from prognostic variables, thus upsetting the simulated water balance. To overcome this limitation, we propose and test an alternative assimilation scheme in which precipitation fluxes are adjusted to achieve the desired changes in simulated TWS. Using a synthetic data assimilation experiment, we show that the scheme improves performance skill in precipitation estimates in general, but that it is more robust for snowfall than for rainfall, and it fails in certain regions with strong horizontal gradients in precipitation. The results demonstrate that assimilation of TWS observations can help correct (adjust) the model’s precipitation forcing and, in turn, enhance model estimates of TWS, snow mass, soil moisture, runoff, and evaporation. A key limitation of the approach is the assumption that all errors in TWS originate from errors in precipitation. Nevertheless, the proposed approach produces more consistent improvements in simulated runoff than the established GRACE data assimilation techniques.

Data Assimilation↗

Technical Report Series on Global Modeling and Data Assimilation: Interannual Variability and Potential Predictability in Reanalysis Products - Volume 13

The Data Assimilation Office (DAO) at Goddard Space Flight Center and the National Center for Environmental Prediction and National Center for Atmospheric Research (NCEP/NCAR) have produced multi-year global assimilations of historical data employing fixed analysis systems. These "reanalysis" products are ideally suited for studying short-term climatic variations. The availability of multiple reanalysis products also provides the opportunity to examine the uncertainty in the reanalysis data. The purpose of this document is to provide an updated estimate of seasonal and interannual variability based on the DAO and NCEP/NCAR reanalyses for the 15-year period 1980-1995. Intercomparisons of the seasonal means and their interannual variations are presented for a variety of prognostic and diagnostic fields. In addition, atmospheric potential predictability is re-examined employing selected DAO reanalysis variables.

Min, Wei↗

A Decadal Hybrid GCM Simulation Using Deep‐Learning‐Based Cloud and Convection Parameterization Generalized to a Warm Climate

A critical challenge for machine‐learning (ML) parameterization in global climate models (GCMs) is to achieve stable, accurate simulations under climates not seen during training. Previous studies have demonstrated promising offline performance and year‐long online stability in aquaplanet simulations but have encountered difficulties in real geography and under climate warming. Here we report that a GCM with real geography configuration using neural‐network‐based cloud and convection parameterization, trained exclusively with present‐day climate data, successfully performs a stable, decade‐long simulation of a warm climate with +4 K sea surface temperature (SST). The neural network (NN) is based on Han et al. (2023, https://doi.org/10.1029/2022ms003508 ) with additional inputs. The simulation captures the global precipitation distribution, surface temperatures, vertical atmospheric structures, and extreme precipitation very well, closely matching simulations from both the superparameterized CAM (SPCAM) and the conventional CAM5 in the warm climate without accuracy degradation compared to those in the baseline climate. Moreover, it produces a climate response to +4 K SST in atmospheric thermodynamic states and circulations similar to those from SPCAM and CAM5. Prognostic ablation tests on NN input variables show that the NN without convective memory as input suffers from numerical instability, and the NN without considering radiative variables and land fraction as input, or with reduced training samples produce less accurate results. To our knowledge, this is the first time an ML parameterization successfully achieves online extrapolation to a warm climate without using additional warm‐climate data for training. It demonstrates the potential of ML‐driven parameterizations for credible long‐term climate projections.

Atmosphere model↗