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Enabling Innovative Research on the International Space Station to Solve the Challenges of A Human Mission to Mars: Results of the ISS4Mars International Workshops 2020–2021

During the ISS4Mars workshops in 2020–2021, personnel from the International Space Station (ISS) partner agencies convened to reflect on scenarios for how the ISS could be used and its operations possibly modified to simulate aspects of a human mission to Mars. Scientific leaders, operations experts, crewmembers, managers, and flight surgeons discussed the five hazards of human spaceflight—gravity transitions, radiation, isolation and confinement, distance from Earth, and hostile closed environments—and considered how an ISS-based analog of Mars transit could benefit assessments and mitigations of these hazards. A focused writing team then discussed the advantages and disadvantages of each approach identified by the workshop participants before developing a set of eight use cases to consider the feasibility of implementing on the ISS. The writing team also identified the prerequisites needed, including ground analog studies simulating a mission to Mars required to verify measurements and procedures, before testing could begin on the ISS. Five of the use cases were considered feasible to assess in simulations using an ISS-based analog of Mars transit if some ground rules and assumptions were met. These five use cases were Earth-independent medical operations, Earth-independent integrated operations, life support and food for a one year duration, lower-body negative pressure as a countermeasure against the effects of exposure to microgravity, and fitness levels after landing. In addition, three more extensive interventions—extended Mars surface operations, a small-volume transit analog, and artificial gravity—were deemed unfeasible for testing on the ISS. Experience gained from the five use cases executed on the ISS may help answer some of the questions in the deferred scenarios, or it may be possible to complete them on another platform (e.g. commercial space station, lunar habitat). Simulating conditions during a Mars mission on the ISS will afford higher fidelity for assessing multiple integrated hazards of human spaceflight, however, ground analogs of Mars missions can be used to ensure effective measures and experimental design before testing begins on the ISS. The strategic concepts refined as part of these workshops were brought to a multilateral forum, Mulitlateral Human Research Planel for Exploration (MHRPE), where ISS partner agencies are now discussing implementation plans to provide new opportunities to use the ISS to prepare for deep space exploration over the coming decade. In this publication we present a summary of the international strategic plans for future research that will enable operations, software, and countermeasures to be developed that will reduce the risk to humans during future crewed missions to Mars.

Human space exploration↗

Spatial Cognitive Performance During Adaptation to Conflicting Tilt-Translation Stimuli as a Sensorimotor Spaceflight Analog

The need to resolve new patterns of sensory feedback in altered gravitoinertial environments requires cognitive processes to develop appropriate reference frames for spatial orientation awareness. The purpose of this study was to examine deficits in spatial cognitive performance during adaptation to conflicting tilt-translation stimuli. Fourteen subjects were tilted within a lighted enclosure that simultaneously translated at one of 3 frequencies. Tilt and translation motion was synchronized to maintain the resultant gravitoinertial force aligned with the longitudinal body axis, resulting in a mismatch analogous to spaceflight in which the canals and vision signal tilt while the otoliths do not. Changes in performance on different spatial cognitive tasks were compared 1) without motion, 2) with tilt motion alone (pitch at 0.15, 0.3 and 0.6 Hz or roll at 0.3 Hz), and 3) with conflicting tilt-translation motion. The adaptation paradigm was continued for up to 30 min or until the onset of nausea. The order of the adaptation conditions were counter-balanced across 4 different test sessions. There was a significant effect of stimulus frequency on both motion sickness and spatial cognitive performance. Only 3 of 14 were able to complete the full 30 min protocol at 0.15 Hz, while 7 of 14 completed 0.3 Hz and 13 of 14 completed 0.6 Hz. There were no changes in simple visual-spatial cognitive tests, e.g., mental rotation or match-to-sample. There were significant deficits during 0.15 Hz adaptation in both accuracy and reaction time during a spatial reference task in which subjects are asked to identify a match of a 3D reoriented cube assemblage. Our results are consistent with antidotal reports of cognitive impairment that are common during sensorimotor adaptation with G-transitions. We conclude that these cognitive deficits stem from the ambiguity of spatial reference frames for central processing of inertial motion cues.

Kayanickupuram, A. J.↗

NASA HRP Immunology Discipline - Use of Terrestrial Analogs

Due to the cost and operational constraints, as well as technical implementation limitations, it is desirous to perform relevant space physiology investigations first in terrestrial 'space analogs'. This is particularly true for initial investigations, which may then provide appropriate focus for subsequent flight investigations, or for mechanistic investigations that simply cannot be performed during spaceflight. Appropriate analog choice is extremely important. There are a wide variety of terrestrial space analogs, each relevant to a particular physiological discipline (or disciplines) and each with a particular fidelity (or lack thereof) to spaceflight, and each with unique operational constraints. The HRP Immunology Discipline is tasked with managing the HRP Risk concerning clinical risk for Astronaut crews related to spaceflight-associated immune dysregulation. Such dysregulation has been documented to occur during spaceflight, and found to persist for the duration of a 6-month ISS mission. Studies continue to characterize the onorbit phenomenon, but it generally consists of diminished immunocyte function, dysregulated cytokine profiles, and persistent herpesvirus reactivation. Causes are thought to synergistically include microgravity, psychological or physiological stress, radiation, and/or circadian misalignment. An appropriate terrestrial analog for immune dysregulation would replicate as many of these influences as possible. Such analogs may include clinostat or bioreactor cell culture (microgravity), hindlimb suspension (stress, fluid shifts, hypokinesis), or human deployment to remote or extreme environments (isolation, stress, circadian). Also, the laboratory setting may be used as an analog, or to augment analogs, such as sleep deprivation/misalignment or human centrifugation to replicate gravitational stress. As an appropriate example of a NASA Disciplines use of Terrestrial space analogs, this talk will discuss spaceflight associated immune dysregulation, terrestrial immune analogs, and recent analog investigations.

Crucian, Brian↗

Use of antarctic analogs to support the space exploration initiative

This report has discussed the Space Exploration Initiative (SEI) and the U.S. Antarctic Program (USAP) in the context of assessing the potential rationale and strategy for conducting a cooperative NASA/NSF (National Science Foundation) effort. Specifically, such an effort would address shared research and data on living and conducting scientific research in isolated, confined, hostile, and remote environments. A review of the respective goals and requirements of NASA and the NSF indicates that numerous opportunities exist to mutually benefit from sharing relevant technologies, data, and systems. Two major conclusions can be drawn: (1) The technologies, experience, and capabilities existing and developing in the aerospace community would enhance scientific research capabilities and the efficiency and effectiveness of operations in Antarctica. The transfer and application of critical technologies (e.g., power, waste management, life support) and collaboration on crew research needs (e.g., human behavior and medical support needs) would streamline the USAP operations and provide the scientific community with advancements in facilities and tools for Antarctic research. (2) Antarctica is the most appropriate earth analog for the environments of the the Moon and Mars. Using Antarctica in this way would contribute substantially to near- and long-term needs and plans for the SEI. Antarctica is one of the few ground-based analogs that would permit comprehensive and integrated studies of three areas deemed critical to productive and safe operations on the Moon and Mars: human health and productivity; innovative scientific research techniques; and reliable, efficient technologies and facilities.

Wharton, Robert↗

Bifurcation and stability in a model of moist convection in a shearing environment

The truncated spectral system (model I) of shallow moist two-dimensional convection discussed by Shirer and Dutton (1979) is expanded to eleven coefficients (model II) in order to include a basic wind. Cloud streets, the atmospheric analog of the solutions to model II, are typically observed in an environment containing a shearing basic motion field. Analysis of the branching behavior of solutions to mode II shows that, if the basic wind direction varies with height, very complex temporal behavior is possible as the modified Rayleigh number HR is increased sufficiently. The first convective solution is periodic, corresponding to a cloud band that propagates downwind; but secondary branching to a two-dimensional torus can occur for larger values of HR. Orientation band formulas are derived whose predictions generally agree with the results of previous studies.

Shirer, H. N.↗

Analytical electron microscopy of biogenic and inorganic carbonates

In the terrestrial sedimentary environment, the mineralogically predominant carbonates are calcite-type minerals (rhombohedral carbonates) and aragonite-type minerals (orthorhombic carbonates). Most common minerals precipitating either inorganically or biogenically are high magnesium calcite and aragonite. High magnesium calcite (with magnesium carbonate substituting for more than 7 mole percent of the calcium carbonate) is stable only at temperatures greater than 700 C or thereabouts, and aragonite is stable only at pressures exceeding several kilobars of confining pressure. Therefore, these carbonates are expected to undergo chemical stabilization in the diagenetic environment to ultimately form stable calcite and dolomite. Because of the strong organic control of carbonate deposition in organisms during biomineralization, the microchemistry and microstructure of invertebrate skeletal material is much different than that present in inorganic carbonate cements. The style of preservation of microstructural features in skeletal material is therefore often quite distinctive when compared to that of inorganic carbonate even though wholesale recrystallization of the sediment has taken place. Microstructural and microchemical comparisons are made between high magnesium calcite echinoderm skeletal material and modern inorganic high magnesium calcite inorganic cements, using analytical electron microscopy and related techniques. Similar comparisons are made between analogous materials which have undergone stabilization in the diagenetic environment. Similar analysis schemes may prove useful in distinguishing between biogenic and inorganic carbonates in returned Martian carbonate samples.

Blake, David F.↗

NASA's Analog Missions: Driving Exploration Through Innovative Testing

Human exploration beyond low-Earth orbit (LEO) will require a unique collection of advanced, innovative technologies and the precise execution of complex and challenging operational concepts. One tool we in the Analog Missions Project at the National Aeronautics and Space Administration (NASA) utilize to validate exploration system architecture concepts and conduct technology demonstrations, while gaining a deeper understanding of system-wide technical and operational challenges, is our analog missions. Analog missions are multi-disciplinary activities that test multiple features of future spaceflight missions in an integrated fashion to gain a deeper understanding of system-level interactions and integrated operations. These missions frequently occur in remote and extreme environments that are representative in one or more ways to that of future spaceflight destinations. They allow us to test robotics, vehicle prototypes, habitats, communications systems, in-situ resource utilization, and human performance as it relates to these technologies. And they allow us to validate architectural concepts, conduct technology demonstrations, and gain a deeper understanding of system-wide technical and operational challenges needed to support crewed missions beyond LEO. As NASA develops a capability driven architecture for transporting crew to a variety of space environments, including the moon, near-Earth asteroids (NEA), Mars, and other destinations, it will use its analog missions to gather requirements and develop the technologies that are necessary to ensure successful human exploration beyond LEO. Currently, there are four analog mission platforms: Research and Technology Studies (RATS), NASA s Extreme Environment Mission Operations (NEEMO), In-Situ Resource Utilization (ISRU), and International Space Station (ISS) Test bed for Analog Research (ISTAR).

Reagan, Marcum L.↗

Laboratory Studies of the Optical Properties and Condensation Processes of Cosmic Dust Particles

A laboratory facility for levitating single isolated dust particles in an electrodynamics balance has been developing at NASA/Marshall Space Flight Center for conducting a variety of experimental, of astrophysical interest. The objective of this research is to employ this innovative experimental technique for studies of the physical and optical properties of the analogs of cosmic grains of 0.2-10 micron size in a chamber with controlled pressure/temperatures simulating astrophysical environments. In particular, we will carry out three classes of experiments to investigate the microphysics of the analogs of interstellar and interplanetary dust grains. (1) Charge characteristics of micron size single dust grains to determine the photoelectric efficiencies, yields, and equilibrium potentials when exposed to UV radiation. These measurements will provide the much-needed photoelectric emission data relating to individual particles as opposed to that for the bulk materials available so far. (2) Infrared optical properties of dust particles obtained by irradiating the particles with radiation from tunable infrared diode lasers and measuring the scattered radiation. Specifically, the complex refractive indices, the extinction coefficients, the scattering phase functions, and the polarization properties of single dust grains of interest in interstellar environments, in the 1-25 micron spectral region will be determined. (3) Condensation experiments to investigate the deposition of volatile gases on colder nucleated particles in dense interstellar clouds and lower planetary atmospheres. The increase in the mass or m/q ratio due to condensation on the particle will be monitored as a function of the dust particle temperature and the partial pressure of the injected volatile gas. The measured data wild permit determination of the sticking efficiencies of volatile gases of astrophysical interest. Preliminary results based on photoelectric emission experiments on 0.2-6.6 micron size silica particles exposed to UV radiation in the 120-200 nm spectral region will be presented.

Abbas, Mian M.↗

Maintaining Human Health for Humans-Mars

The Human Health Research Program states that Radiation is the most challenging hazard to human spaceflight beyond LEO. The International Space Station provides an analog for evaluating techniques for dealing with Altered Gravity, the Radiation Environment of the ISS is only about 45% of the deep space values where radiation due to Galactic Cosmic Rays (GCR) dominate the spectrum. The Moon and cis-lunar space are being considered as a Mars Analog training ground for preparing crews for human mission to Mars. Spending more than 200 days in deep space is considered unsafe based on our current proxy for lifetime radiation dose. The paper outlines a way forward for spending days training near the Moon and for completing roundtrip missions to Mars while remaining below the current proxy. In the first case, a GCR overcoat shields crews from radiation during cis-lunar activities before making fast transits without in-space GCR overcoats to and from Mars. This case requires continued maturation of low TRL propulsion and power technologies currently around 4 to 5 while depending on repeatable reductions in launch costs by a factor of 6 expected of current reusable rockets. The second case requires no new technology development except for the expectation that the next near-term generation of reusable rockets will reduce launch costs by a factor of around 14. Five trajectories and GCR overcoat sizes for all mission legs are presented herein to illustrate the opportunities to maintain human health for Humans-Mars missions.

Robert W Moses↗

Human-in-the-Loop Operations over Time Delay: NASA Analog Missions Lessons Learned

Teams at NASA have conducted studies of time-delayed communications as it effects human exploration. In October 2012, the Advanced Exploration Systems (AES) Analog Missions project conducted a Technical Interchange Meeting (TIM) with the primary stakeholders to share information and experiences of studying time delay, to build a coherent picture of how studies are covering the problem domain, and to determine possible forward plans (including how to best communicate study results and lessons learned, how to inform future studies and mission plans, and how to drive potential development efforts). This initial meeting s participants included personnel from multiple NASA centers (HQ, JSC, KSC, ARC, and JPL), academia, and ESA. It included all of the known studies, analog missions, and tests of time delayed communications dating back to the Apollo missions including NASA Extreme Environment Mission Operations (NEEMO), Desert Research and Technology Studies (DRATS/RATS), International Space Station Test-bed for Analog Research (ISTAR), Pavilion Lake Research Project (PLRP), Mars 520, JPL Mars Orbiters/Rovers, Advanced Mission Operations (AMO), Devon Island analog missions, and Apollo experiences. Additionally, the meeting attempted to capture all of the various functional perspectives via presentations by disciplines including mission operations (flight director and mission planning), communications, crew, Capcom, Extra-Vehicular Activity (EVA), Behavioral Health and Performance (BHP), Medical/Surgeon, Science, Education and Public Outreach (EPO), and data management. The paper summarizes the descriptions and results from each of the activities discussed at the TIM and includes several recommendations captured in the meeting for dealing with time delay in human exploration along with recommendations for future development and studies to address this issue.

Rader, Steven N.↗

Data and results of a laboratory investigation of microprocessor upset caused by simulated lightning-induced analog transients

A methodology was developed a assess the upset susceptibility/reliability of a computer system onboard an aircraft flying through a lightning environment. Upset error modes in a general purpose microprocessor were studied. The upset tests involved the random input of analog transients which model lightning induced signals onto interface lines of an 8080 based microcomputer from which upset error data was recorded. The program code on the microprocessor during tests is designed to exercise all of the machine cycles and memory addressing techniques implemented in the 8080 central processing unit. A statistical analysis is presented in which possible correlations are established between the probability of upset occurrence and transient signal inputs during specific processing states and operations. A stochastic upset susceptibility model for the 8080 microprocessor is presented. The susceptibility of this microprocessor to upset, once analog transients have entered the system, is determined analytically by calculating the state probabilities of the stochastic model.

Belcastro, C. M.↗

GeoLab in NASA's Pressurized Excursion Module: First Results from the 2010 Field Trials

Before humans explore other planets, NASA must develop advanced techniques for collection, preservation and return of unique extraterrestrial samples. To help evaluate hardware requirements and operational concepts for future sample-return missions, we designed and built GeoLab our first generation lab for geological samples into NASA s Habitat Demonstration Unit in the Pressurized Excursion Module (HDU1-PEM). The center of GeoLab is a glovebox for the examination of samples in a shirt-sleeve environment. As part of a deployable habitat, GeoLab can participate in NASA s analog missions that simulate planetary exploration activities and support the testing of relevant technologies for collecting and handling geological samples. Over time, these tests will evaluate sample handling environments (field and lab), sampling tools and analytical instruments, and different scenarios involving both robotic and human procedures. The GeoLab design supports evolving tests and configurations. The glovebox is mounted on the habitat bulkhead, with three sample pass-though chambers that allow for direct sample transfer into the glovebox from the outside. The glovebox design and construction (low-particle shedding, minimally off-gassing materials) provides a clean environment to reduce sample contamination; in the future, we will integrate a positive pressure, enriched nitrogen atmosphere. The glovebox is equipped with configurable instrument ports. The 2010 test included a mass balance, a stereomicroscope with a HD camera for detailed imaging of samples, and a handheld XRF analyzer for preliminary geochemical characterization of samples. Network cameras provided context imagery and sample handling activities. We present early results from the initial field trial of GeoLab during the 2010 Desert Research and Technology Studies (D-RATS) planetary analog test near Flagstaff AZ. The 2010 D-RATS mission involved two rovers, the habitat with GeoLab, four crew members, and a team of scientists and flight controllers. The crewed rovers conducted geological traverses and collected samples on the planetary surface. Selected samples were transferred into GeoLab for detailed examination and initial analysis, providing critical data to the science team for evaluation and prioritization of samples.

Evans, Cynthia A.↗

Measuring the Internal Environment of Solid Rocket Motors During Ignition

A new instrumentation system has been developed to measure the internal environment of solid rocket test motors during motor ignition. The system leverages conventional, analog gages with custom designed, electronics modules to provide safe, accurate, high speed data acquisition capability. To date, the instrumentation system has been demonstrated in a laboratory environment and on subscale static fire test motors ranging in size from 5-inches to 24-inches in diameter. Ultimately, this system is intended to be installed on a full-scale Reusable Solid Rocket Motor. This paper explains the need for the data, the components and capabilities of the system, and the test results.

Weisenberg, Brent↗

TRIDENT Drill Validation at Mars and Lunar Analog Field Sites

Drilling on Earth is typically a human-intensive activity. Drilling on other planets is further complicated by the lack of prior local field surveys of their target area, hence blindly drilling into uncertain target rocks. Field conditions on the Moon or Mars are also different than for shallow drilling on Earth: lower temperatures and pressures, less power available, low masses (hence less weight-on-bit). Given the cost of transport from Earth, no drilling muds or working fluids are likely to be available to carry away cuttings. And impact-gardened regolith and dust vary mechanically and texturally from most terrestrial soils. The Regolith and Ice Drill for Exploration of New Terrains (TRIDENT) is a rotary-percussive 1m-class drill from Honeybee Robotics. It is low-power (rotary and percussive actuators are 200 W each) and lightweight (<20 kg) with the maximum weight on bit limited to 200 N. TRIDENT has been manifested for the Volatiles Investigating Polar Exploration Rover (VIPER) and PRIME-1 lunar south pole missions in 2024, has previously been field tested at a hot, dry analog site in the Atacama Desert, and in lunar conditions in thermal vacuum chamber tests. TRIDENT was also part of the 2019 Icebreaker Mars Discovery proposal, as well as in the Mars Life Explorer concept. During ARADS tests, drill control and fault recovery automation software enabled hands-off operations of a rover-mounted TRIDENT drill. TRIDENT Drill Analog Site Validation: Past TRIDENT tests in thermal vacuum (TVAC) chambers targeted containers of manufactured lunar simulants with added volatiles. 2022 TRIDENT ambient testing at NASA Ames drilled into cemented lunar simulant materials. Low cuttings-permeability led to cuttings buildup, and drill choking and binding was observed. The Atacama analog site in ARADS had desiccated unconsolidated sediments that did not challenge the TRIDENT design. However, lunar polar regolith is expected to be diverse and heterogeneous with varying clast sizes, with abundant impactites and perhaps subsurface ice deposits. Neither the simulants nor Atacama testing had completely covered the TRIDENT-targeted field characteristics, motivating further analog tests prior to the planned lunar missions. To gain more insight into the behavior of the TRIDENT hardware in diverse impactites and subsurface ice, and to verify the software automation in that environment, in August 2023 TRIDENT was brought to Haughton Crater, a field analog site in the Canadian Arctic. In September 2023 the same drill was brought to the Bishop Tuff in southern California to verify whether drilling binding behaviors previously seen in lunar simulant testing would be observed in naturally occurring fine-grained massive layers. The ~22 Ma Haughton Crater impact structure is located at 75 ̊22’ N, 89 ̊41’ W, on northwestern Devon Island, Nunavut, Canada. Numerous deposits of pale-grey crater-fill polymictic impact-melt breccia are found within the crater with a typical thickness reaching ~125 m or greater and covering ~60 km -2 . An approximately 600m-thick permafrost layer is also present with ice typically found within 0.5-0.6m of the surface. The volcanic tableland north of Bishop, CA exposes densely welded tuff laid down during the eruption that created the Long Valley Caldera at approximately 0.76 Ma. Extensional faults and the Owens River gorge expose cross-sections across the plateau. The area is viewed as an analog site for Mars features believed to be of pyroclastic origin. Results: Haughton Crater.Drilling tests were conducted 8-13 August 2023 at a previously undisturbed area separated 5-10 m from past years’ Drill Hill test sites (75.4208, -089.7613). In six days, TRIDENT drilled 8 holes to nearly 1 m depth each, totaling 7.80 m. The active layer/ice boundary was at ~67 cm depth, with a total of approximately 2.4 m drilled into ice or ice-cemented impact breccia. During drilling, five drill fault states were observed and successfully recovered. Holes 23-1, 4 and 7 were drilled under manual control, using Honeybee’s Thorax user interface. Holes 23-5, 6, and 8 were drilled with the Ames IBexec automated drilling control software. TRIDENT was observed to have little difficulty in the thawed uncemented impact breccia above the active layer boundary, but required percussion to make slower headway in the ice-cemented breccia. In Hole 23-7 (Fig.1), drilling slowed down in a massive unit just above the active-layer boundary (perhaps a large rock extending into the ice-cementation?), with only 7cm progress made in 27 minutes of high auger torque and constant percussion, leading to a choking fault and then a binding fault. A similar pattern had been observed in TRIDENT Rio Tinto test data from 2017 [6] as well as in the 2022laboratory tests.Bishop Tuff.A team from NASA Ames and the US Geological Survey deployed the same TRIDENT drill to Bishop Sites 1B and 1C (37.4203, -118.4289; 37.4265, -118.4215) on 13-16 September 2023, on the Bishop Tuff plateau. A third drill site was used 17-18 September 2023(37.4598, -118.3667) in an abandoned pumice mine. Four holes (totaling 2.5m depth) were drilled into the fine-grained, meters-thick tuff units at Sites 1B and 1C, and a further two boreholes (totaling 1.98m depth) were made at the pumice site. Drill behavior in the tuff below 10 cm depth was similar to that seen at 65-74 cm depth in Haughton Hole 23-7 (Fig. 1) and that seen in the 2022 lab simulant drilling. Drill safety torque limits were exceeded multiple times resulting in drill stops downhole. These freezes then required external added torques (with a pipe wrench) to resume rotation, to unstick the drill for withdrawal. To prevent this choking and binding behavior we found that more-frequent cuttings removal was necessary, e.g., reducing the “drill bite” size from the nominal 10 cm to 2 cm per bite --bringing the auger up to the surface more frequently, as seen in Bishop Site 1C Hole 2 (Fig.2). This permitted slow progress without drill binding and without external interventions. Conversely, TRIDENT drilling in the more porous pumice target material showed no cuttings buildup issue, and single bites as large as 40 cm were demonstrated. Discussion: We observed that TRIDENT easily penetrated unconsolidated heterogeneous soils (both above the active layer boundary at Haughton and previously in the Atacama). Cemented or consolidated targets that were cuttings-permeable (icy impact breccia, pumice) required more energy applied and percussion. However, in non-cuttings-permeable targets (welded microporous tuff, cemented simulants, boulder) TRIDENT was observed to be prone to excessive cuttings accumulation leading to choking/binding faults and stalling. The wedge cutting bit, used by TRIDENT in field tests and in its flight versions, pulverizes the target rock and creates fine cuttings that ideally are transported up the auger spirals for removal. In porous, fractured or vesicular target materials (such as at the Bishop pumice site) a significant portion of the cuttings are pushed aside, but for non-fractured, microporous targets the cuttings remain in the borehole and accumulate. Rock powder is relatively incompressible as a working fluid at only 100-200N downward force (TRIDENT limits) and hence eventual drilling progress slows or stops. Our recommended strategy for improving TRIDENT cuttings removal in massive target units with low cuttings-permeability is to reduce TRIDENT bite sizes when encountering these units, from 10cm to as little as 1-2cm, to effectively bail the accumulating cuttings. This approach was demonstrated to reduce choking and allowed slow progress to continue in cuttings-impermeable microporous target units (viz. the Bishop tuff in our September 2023 tests or cemented simulants in 2022 ambient tests).

robotic drilling↗

Immune Function Changes during a Spaceflight-Analog Undersea Mission

There is ample evidence to suggest that space flight leads to immune system dysregulation. This may be a result of microgravity, confinement, physiological stress, radiation, environment or other mission-associated factors. It is attractive to utilize ground-based spaceflight analogs as appropriate to investigate this phenomenon. For spaceflight-associated immune dysregulation (SAID), the authors believe the most appropriate analogs might be NEEMO (short duration, Shuttle analog), Antarctic winter-over (long-duration, ISS analog) and the Haughton Mars Project in the Canadian Arctic (intermediate-duration). Each of these analogs replicate isolation, mission-associated stress, disrupted circadian rhythms, and other aspects of flight thought to contribute to SAID. To validate NEEMO as a flight analog with respect to SAID, a pilot study was conducted during the NEEMO-12 and 13 missions during 2007. Assays were performed that assessed immune status, physiological stress and latent viral reactivation. Blood and saliva samples were collected at pre-, mid-, and post-mission timepoints.

Crucian, Brian↗

Effects of Communication Delay on Human Spaceflight Missions

Missions onboard the International Space Station rely on the real-time availability of a large ground team of system experts to command the vehicle, solve safety-critical problems, and guide the crew during complex operations. Also, in Low Earth Orbit (LEO), supplies can be sent and crews evacuated quite quickly if needed. Future missions Beyond Low Earth Orbit (BLEO) will not have this 24/7, real-time safety net as communication latency increases, resupply difficulty increases, and evacuation opportunities diminish. There are few, if any, terrestrial analogs for human spaceflight missions BLEO that reflect the conditions—including extreme environments, long mission durations, and small crew sizes – that make these missions so high risk. Studies on specific conditions, such as communication delays and asynchronous interactions, have been performed in NASA Earth-based analog missions and have found that communication delays can disrupt ground-crew interactions and adversely impact team performance. However, there are gaps and limitations in studies conducted to date, notably on human spacecraft system failure response and recovery, the impacts of shorter lunar-relevant communication delays on complex operations, and the effectiveness of countermeasures. The work presented here breaks down real anomalies that occurred on ISS and Apollo missions and creates example scenarios fort Lunar Surface and Mars missions to explore the impact of communication delays of varying length on onboard operations and mission outcomes. Our analyses indicate that short communication delays (e.g., seconds to a minute) adversely impact the ability for ground to provide real-time oversight and guidance and to catch quickly emerging problems in time. Longer communication delays (e.g., up to 40 minutes on Mars missions) call for a shift of responsibility for tactical operations from ground to crew; crew must make time-critical decisions independently and respond to time-critical vehicle anomalies to prevent consequences.

human-systems integration↗