Automated dectection of potentially hazardous near-Earth-object encounters
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Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Unmanned aircraft systems (UAS) will be required to equip with a detect-and-avoid (DAA) system in order to satisfy the federal aviation regulations to remain well clear of other aircraft. For a DAA system to satisfy the requirement to stay well clear of other airborne traffic, a quantitative definition of well clear needs to be defined and evaluated. This study investigates the implications of UAS using proposed well clear definitions as a separation standard for conducting operations in the National Airspace System (NAS). The first analysis considers three well clear definitions and presents the relative state conditions of intruder aircraft as they encroach upon the well clear boundary. The second analysis focuses on the definition of the alerting criteria needed to inform the UAS operator of a potential loss of well clear. All analyses are conducted in a NAS-wide fast-time simulation environment using UAS aircraft models, proposed UAS missions, and historical air defense radar data to populate the background traffic operating under visual flight rules. The results presented in this study inform the safety case, requirements development, and the operational environment for DAA minimum operational performance standards.
The galileo spacecraft was launched on October 18, 1989 towards Jupiter using the Venus-Earth-Earth Gravity Assist (VEEGA) trajectory.
The assembly of two monomeric constructs spanning segments 1-199 (MPro 1-199 ) and 10-306 (MPro 10-306 ) of SARS-CoV-2 main protease (MPro) was examined to assess the existence of a transient heterodimer intermediate in the N-terminal autoprocessing pathway of MPro model precursor. Together, they form a heterodimer population accompanied by a 13-fold increase in catalytic activity. Addition of inhibitor GC373 to the proteins increases the activity further by ~7-fold with a 1:1 complex and higher order assemblies approaching 1:2 and 2:2 molecules of MPro 1-199 and MPro 10-306 detectable by analytical ultracentrifugation and native mass estimation by light scattering. Assemblies larger than a heterodimer (1:1) are discussed in terms of alternate pathways of domain III association, either through switching the location of helix 201 to 214 onto a second helical domain of MPro 10-306 and vice versa or direct interdomain III contacts like that of the native dimer, based on known structures and AlphaFold 3 prediction, respectively. At a constant concentration of MPro 1-199 with molar excess of GC373, the rate of substrate hydrolysis displays first order dependency on the MPro 10-306 concentration and vice versa. An equimolar composition of the two proteins with excess GC373 exhibits half-maximal activity at ~6 μM MPro 1-199 . Catalytic activity arises primarily from MPro 1-199 and is dependent on the interface interactions involving the N-finger residues 1 to 9 of MPro 1-199 and E290 of MPro 10-306 . Importantly, our results confirm that a single N-finger region with its associated intersubunit contacts is sufficient to form a heterodimeric MPro intermediate with enhanced catalytic activity.
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Turbulence governs the development and erosion of wind farm wakes, which can deplete the offshore wind resource. Therefore, an accurate understanding of atmospheric turbulence is required to support the rapid growth of offshore wind energy. Using 13 months of lidar observations off the coast of Massachusetts, we find that offshore wind plants at the site will experience very low turbulence, quantified as lidar turbulence intensity, especially in summer, when the wind flows from the open ocean. Moreover, the lowest turbulence regimes are often associated with large wind veer conditions, which can impact the effectiveness of wake steering solutions.
Collective neutrino oscillations are typically studied using the lowest-order quantum kinetic equation, also known as the mean-field approximation. However, some recent quantum many-body simulations suggest that quantum entanglement among neutrinos may be important and may result in flavor equilibration of the neutrino gas. In this work, we develop new quantum models for neutrino gases in which any pair of neutrinos can interact at most once in their lifetimes. A key parameter of our models is γ = μ Δ z , where μ is the neutrino coupling strength, which is proportional to the neutrino density, and Δ z is the duration over which a pair of neutrinos can interact each time. Our models reduce to the mean-field approach in the limit γ → 0 and achieve flavor equilibration in time t ≫ ( γ μ ) − 1 . These models demonstrate the emergence of coherent flavor oscillations from the particle perspective and may help elucidate the role of quantum entanglement in collective neutrino oscillations. Published by the American Physical Society 2024
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Rigorous understanding on the self-assembly of colloidal nanocrystals is crucial to develop tailored nanostructured materials for energy storage, sensing, and optical fields. Despite extensive studies on the self-assembly, a mechanistic understanding of self-assembly under an external field still remains an ongoing challenge. Here, in this work, we used optical tweezers that impose an external attractive force field, resulting in the self-assembly of alpha-phase sodium yttrium fluoride nanocrystals. The dynamic force that is strongly dependent on the surface roughness of the nanocrystals is shown to be a decisive factor for a direct contact between the nanocrystals, manifested by the roughness-dependent hydrodynamic resistivity and Langevin dynamic simulations. Our study provides direct evidence that the role of dynamics is equally important in understanding the self-assembly, which has been rarely observed in the self-assembly in contrast with many studies on the equilibrium forces. These results may have further impact in other fields, such as having explanatory power for the probability of nonclassical crystal growth or the structure of viral spike proteins that affect the probability of viruses binding with cells.
Clostridium thermocellum , a promising candidate for consolidated bioprocessing, has been subjected to numerous engineering strategies for enhanced bioethanol production. Measurements of intracellular metabolites at substrate concentrations high enough (>50 g/L) to allow the production of industrially relevant titers of ethanol would inform efforts toward this end but have been difficult due to the production of a viscous substance that interferes with the filtration and quenching steps during metabolite extraction. To determine whether this problem is unique to C. thermocellum , we performed filtration experiments with other organisms that have been engineered for high-titer ethanol production, including Escherichia coli and Thermoanaerobacterium saccharolyticum . Here, we addressed the problem through a series of improvements, including active pH control (to reduce problems with viscosity), investigation of different filter materials and pore sizes (to increase the filtration capacity), and correction for extracellular metabolite concentrations, and we developed a technique for more accurate intracellular metabolite measurements at elevated substrate concentrations.
This report provides screenshots of online training on how to use ear loop, tie back, and double elastic face masks made of cloth, surgical, KN95, N95 or homemade materials.
Many marine renewable energy (MRE) technologies, including floating or midwater wave and tidal devices, require mooring systems (i.e., mooring lines and anchors) to maintain their position within the water column or on the sea surface. In the case of some devices such as tidal kites, these lines and cables can be highly dynamic. An array of non-bottom-mounted devices may also include transmission cables within the water column interconnecting devices to one another, or to offshore substations or hubs on the seabed. The potential for these lines and cables to present hazards for marine animals that may become entangled or entrapped in them, or confused by their presence remains an issue of uncertainty. The degree to which mitigation to avoid or reduce entanglement risk might be required for future MRE installations is yet to be determined, pending greater understanding of the actual nature of the risk. In this chapter, the entanglement or entrapment of a marine animal is defined as the cause to become caught in a system without possibility of escaping. https://tethys.pnnl.gov/publications/state-of-the-science-2020-chapter-8-moorings
In our initial study on the high-voltage 5 V cobalt-free spinel LiNi 0.5 Mn 1.5 O 4 (LNMO) cathode, we discovered a severe delamination issue in the laminates when cycled at a high upper cut-off voltage (UCV) of 4.95 V, especially when a large cell format was used. This delamination problem prompted us to investigate further by studying the transition metal (TM) dissolution mechanism of cobalt-free LNMO cathodes, and as a comparison, some cobalt-containing lithium nickel manganese cobalt oxides (NMC) cathodes, as the leachates from the soaking experiment might be the culprit for the delamination. Unlike other previous reports, we are interested in the intrinsic stability of the cathode in the presence of a baseline Gen2 electrolyte consisting of 1.2 M of LiPF 6 in ethylene carbonate/ethyl methyl carbonate (EC/EMC), similar to a storage condition. The electrode laminates (transition metal oxides, transition metal oxides, TMOs, coated on an Al current collector with a loading level of around 2.5 mAh/cm 2 ) or the TMO powders (pure commercial quality spinel LNMO, NMC, etc.) were stored in the baseline solution, and the transition metal dissolution was studied through nuclear magnetic resonance, such as 1 H NMR, 19 F NMR, scanning electron microscope (SEM), X-ray photoelectron spectroscopy (XPS) and inductively coupled plasma mass spectrometry (ICP-MS). Significant electrolyte decomposition was observed and could be the cause that leads to the TM dissolution of LNMO. To address this TM dissolution, additives were introduced into the baseline electrolyte, effectively alleviating the issue of TM dissolution. The results suggest that the observed delamination is caused by electrolyte decompositions that lead to etching, and additives such as lithium difluorooxalato borate and p-toluenesulfonyl isocyanate can alleviate this issue by forming a firm cathode electrolyte interface. This study provides a new perspective on cell degradation induced by electrode/electrolyte interactions under storage conditions.