Results for “IN-FLIGHT MONITORING” — Page 21

NASA NTRS2013

Biomedical Results of the Space Shuttle Program

The Space Shuttle Program (SSP), which was triumphantly completed by the flight of STS-135 on July 21, 2011, holds a special place in the history of Human Space Exploration. For the first time, a vehicle was built that could perform multiple flights in space and return to Earth. Many important questions regarding the ability of humans to adapt and function in space have been answered during the 30 years since the SSP was launched and many lessons have been learned. The multidisciplinary studies conducted during this program allowed NASA to define the normal responses and potential pathologic changes of the major physiological systems to short-duration space flights. The program significantly contributed to the development of in-flight medical care capabilities and multiple countermeasures. A comprehensive system of preflight, in-flight, and post-flight monitoring of the astronauts was built. It is important to emphasize that the SSP was essential for building the International Space Station (ISS) that significantly expanded the boundaries of space research, allowing for planning of long-term near-terrestrial and extraterrestrial missions. As the program was coming to completion, a decision was made by the NASA Lyndon B. Johnson Space Center Human Research Program senior management to summarize the medico-biological results of the SSP in one comprehensive edition. This was quite an ambitious goal. It required selection of a group of experts in different areas to become the chapters lead authors. These experts were charged with the task of reviewing what was learned in the consequent fields to make the chapters a comprehensive source of information for planning of research, operational activities, and medical care for future missions. We hope that we were able to accomplish this goal and the book will serve as a reliable reference edition for the international space biomedicine community, for new generation of space researchers and Flight Surgeons, as well as for all those interested in space exploration. As space exploration continues, the major question of whether humans are capable of adapting to long-term presence and adequately functioning in space habitats will remain open for a long time. we expect that the comprehensive review of the medico-biological results of the SSP along with the data collected during the missions on the space stations (the Russian space station _Mir_ and ISS) provides a good starting point in seeking the answer to this question.

Diana Risin↗

NASA NTRSDate not supplied

An Oculometric Standard to Assess the Performance of the Ocular System for Long Duration Spaceflight

Changes in the human brain, due to spaceflight, have been a challenge to the space program since its inception; a challenge that is becoming more acute as extended International Space Station (ISS) missions become routine, a return to crewed lunar exploration is about to begin, and a multi-year crewed trip to Mars is being planned. Determining the extent to which neurophysiological adaptations may adversely impact performance in operational tasks, assessing the full-time course of these changes, and identifying/mitigating any potential long-term health consequences are crucial steps required to enable safe crew-autonomous, long-duration, deep-space missions. Vision is the predominant perceptual sense used to guide cognition and motor control in humans. Thus, it is critical for the success of any future, long-duration mission to understand how long-term exposure to microgravity and to other stressors of spaceflight and their interactions, impact visual function. This is an especially challenging task given the small and disparate samples from which we have been and will be able to collect human performance data. NASA has recently been carefully tracking spaceflight-induced ophthalmic changes, driven in large part by the fluid shifts related to microgravity. In particular, a recent study of Optical Coherence Tomography (OCT) postflight measures revealed that more than two-thirds of US crew members experience significant increases in retinal thickness after 6month or longer ISS missions. Space Associated Neuro-ocular Syndrome (SANS) also includes visual acuity decrements and other ocular structural changes that could adversely impact in-flight performance as missions become longer. However, the impact of spaceflight on the visual system is not limited to the retina. Recent comparisons of pre-and post-flight brain images have revealed structural changes throughout the brain that implicate visual, visuomotor, and visual-cognitive pathways, consistent with observed functional impacts (e.g., decreased speed/accuracy/timing of fine goal-oriented movements). Current limitations on inflight testing make it very difficult to determine when and under what conditions SANS and other disruptions of human neurological subsystems arise. Currently, one cannot anticipate the time course and extent of impairment and recovery. This study addresses this knowledge gap by creating an integrated framework of the relevant existing literature on visual and oculomotor function during spaceflight with an eye towards complementing current structural measures of visuomotor impairment with new oculometric standard measures. Using eye-movement based visual function assessment and diagnostics would provide a valuable enhancement of crew health and performance monitoring in support of deepspace exploration.

Vision↗

NASA NTRSDate not supplied

Overview and Performance of the LOFTID Instrumentation Suite

NASA’s Hypersonic Inflatable Aerodynamic Decelerator (HIAD) is an enabling technology that facilitates atmospheric entry of heavy payloads to planets such as Earth and Mars using a deployable aeroshell. The deployable nature of the HIAD technology allows it to overcome the size constraints imposed on current rigid aeroshell entry systems. This enables use of larger aeroshells resulting in increased entry system performance (e.g. higher payload mass and/or volume, higher landing altitude at Mars). On November 10th, 2022 the Low-Earth Orbit Flight Test of an Inflatable Decelerator (LOFTID) was launched out of Vandenberg Air Force Base as a secondary payload on an Atlas V rocket. After the primary payload was delivered to its orbit, the LOFTID reentry vehicle was inflated, positioned, and then separated to reenter Earth’s atmosphere at a velocity of 8.1km/s, ultimately splashing down safely in the Pacific Ocean. The flight successfully demonstrated a 6m diameter, 70-deg sphere-cone HIAD on a high-energy orbital reentry. This demonstration has provided invaluable fight data essential to characterize the vehicle performance and support the ongoing effort to further scale the HIAD technology to vehicles of 10m in diameter or greater. Aeroshells of this scale are applicable to near-term commercial applications and future NASA robotic and human exploration missions. LOFTID incorporated an extensive instrumentation suite totaling over 150 science measurements. This included thermocouples, total heat flux sensors, and a radiometer to characterize the aeroheating environment and aeroshell thermal response. An Inertial Measurement Unit (IMU), Global Positioning System (GPS), and flush air data system was included to allow post-flight reconstruction of the vehicle trajectory including a decoupling of the aerodynamics from the atmospheric density. Loadcells were used to measure HIAD structural response during entry, and cameras (both visual-spectrum and infrared) were mounted on the aft segment looking at the aeroshell to monitor structural deflection and surface temperature distribution. Finally, a single up-look camera was included which has provided a surprising amount of science potential from the spectacular footage. In addition to the primary instrumentation suite, a new Fiber Optic Sensing System (FOSS) was used to provide global temperature distributions as a technology demonstration. The system provided over 200 thermal measurements creating a thermal map for the backside of the nose Flexible Thermal Protection System. Another pair of FOSS cables were run along the rigid center structure and measured the temperature response to the vehicle wake environment. The LOFTID instrumentation suite leveraged Agency-wide expertise, with hardware development occurring at Ames Research Center, Langley Research Center, Marshall Space Flight Center, and Armstrong Flight Research Center. This paper will discuss the instrumentation selected for LOFTID, a summary of sensor in-flight performance, and will provide examples of data products from the post-flight analysis effort.

Gregory T Swanson↗

NASA NTRSDate not supplied

Overview and Performance of the LOFTID Instrumentation Suite

NASA’s Hypersonic Inflatable Aerodynamic Decelerator (HIAD) is an enabling technology that facilitates atmospheric entry of heavy payloads to planets such as Earth and Mars using a deployable aeroshell. The deployable nature of the HIAD technology allows it to overcome the size constraints imposed on current rigid aeroshell entry systems. This enables use of larger aeroshells resulting in increased entry system performance (e.g. higher payload mass and/or volume, higher landing altitude at Mars). On November 10th, 2022 the Low-Earth Orbit Flight Test of an Inflatable Decelerator (LOFTID) was launched out of Vandenberg Air Force Base as a secondary payload on an Atlas V rocket. After the primary payload was delivered to its orbit, the LOFTID reentry vehicle was inflated, positioned, and then separated to reenter Earth’s atmosphere at a velocity of 8.1km/s, ultimately splashing down safely in the Pacific Ocean. The flight successfully demonstrated a 6m diameter, 70-deg sphere-cone HIAD on a high-energy orbital reentry. This demonstration has provided invaluable fight data essential to characterize the vehicle performance and support the ongoing effort to further scale the HIAD technology to vehicles of 10m in diameter or greater. Aeroshells of this scale are applicable to near-term commercial applications and future NASA robotic and human exploration missions. LOFTID incorporated an extensive instrumentation suite totaling over 150 science measurements. This included thermocouples, total heat flux sensors, and a radiometer to characterize the aeroheating environment and aeroshell thermal response. An Inertial Measurement Unit (IMU), Global Positioning System (GPS), and flush air data system was included to allow post-flight reconstruction of the vehicle trajectory including a decoupling of the aerodynamics from the atmospheric density. Loadcells were used to measure HIAD structural response during entry, and cameras (both visual-spectrum and infrared) were mounted on the aft segment looking at the aeroshell to monitor structural deflection and surface temperature distribution. Finally, a single up-look camera was included which has provided a surprising amount of science potential from the spectacular footage. In addition to the primary instrumentation suite, a new Fiber Optic Sensing System (FOSS) was used to provide global temperature distributions as a technology demonstration. The system provided over 200 thermal measurements creating a thermal map for the backside of the nose Flexible Thermal Protection System. Another pair of FOSS cables were run along the rigid center structure and measured the temperature response to the vehicle wake environment. The LOFTID instrumentation suite leveraged Agency-wide expertise, with hardware development occurring at Ames Research Center, Langley Research Center, Marshall Space Flight Center, and Armstrong Flight Research Center. This paper will discuss the instrumentation selected for LOFTID, a summary of sensor in-flight performance, and will provide examples of data products from the post-flight analysis effort.

Greg Swanson↗

NASA NTRSDate not supplied

Earth Independent Medical Operations (EIMO) Datascope: Challenges and Potential Solutions

Data flows and storage/retrieval capacity are severely constrained during missions in space and challenges will become even greater during exploration class missions. There is a need for an artificial intelligence (AI)-based clinical decision support system (CDSS) to monitor and analyze data to provide real-time consultative support for crew medical officer (CMO) decision-making. EIMO is defined as the gradual transition of medical care and decision making from terrestrial to space-based assets, enabling support of astronaut health and performance and reducing overall mission risk. While a hallmark of this paradigm shift from low-earth orbit is that on-board care will increasingly become the responsibility of the astronauts for primary management and decision making, terrestrial assets will continue to be paramount in pre-mission screening and planning, as well as prevention, health maintenance and long-term care contingencies. New capabilities and systems that enable progressively more robust and resilient systems and crews will be necessary to reduce risk and increase probability of deep space exploration mission success. An aspiration for EIMO is to develop AI-enhanced solutions for analysis of crew health & performance data and to facilitate clinical decision support for autonomous medical operations. A “system of systems” approach is envisioned whereby EIMO will deploy AI-supported natural language processing and machine learning (ML) techniques to utilize embedded reference databases and real-time data streams [input vectors] from multiple data sources. Constituent input vectors may include environmental controls, countermeasures data, behavioral data, physiologic wearables, point-of-care laboratory tests, personalized medical records, inventory trade space risk assessments, COTS medical databases, and ground support inputs. An ideal AI capability would possess trained fusion algorithms to cross reference input vectors with medical ‘knowledge’ [cultivated database] to stratify relevant data streams for predictive and actionable capabilities. In addition, EIMO will feature mobility, in that it can be accessed and can push/pull data within and between multiple vehicles/habitats. Large amounts and variable sources of data can be leveraged to diagnose, inform treatment strategies, and potentially predict medical events and performance decrements. Inclusion of advanced training tools using extended reality will enable increasingly autonomous medical care to aid a CMO when ground support is unavailable or time-delayed beyond required action window, e.g., emergent medical situations. EIMO CDSS would require very large datasets to train pre-flight and significant amounts of data are needed to support ML via in-flight CDSS operations. An additional challenge will be to find sufficient data to train a model relevant to astronaut demographics. The rapid, accelerating evolution of this field creates a propitious solution space to leverage multi-modal AI through public-private partnership(s). The status of multi-modal AI systems today would preclude their use for long duration missions as they remain unreliable and are subject to “digital hallucinations” and other errors that could pose operational risk. A federated labs structure is being considered to test and optimize data flow from the multiple input vectors leading to field testing in suitable ground/flight analogs. Critical to the success of an EIMO CDSS will be integration and interoperability and success will be defined by a system that can serve as an in-flight medical consult for the CMO providing critical support during medical contingencies. Benefits to terrestrial medicine may be significant as an outflow of the EIMO medical system, particularly for remote areas and communities lacking significant infrastructure, personnel and resources.

J Lemery↗

NASA NTRS2024

Earth Independent Medical Operations (EIMO) Datascope: Challenges and Potential Solutions

Data flows and storage/retrieval capacity are severely constrained during missions in space and challenges will become even greater during exploration class missions. There is a need for an artificial intelligence (AI)-based clinical decision support system (CDSS) to monitor and analyze data to provide real-time consultative support for crew medical officer (CMO) decision-making. EIMO is defined as the gradual transition of medical care and decision making from terrestrial to space-based assets, enabling support of astronaut health and performance and reducing overall mission risk. While a hallmark of this paradigm shift from low-earth orbit is that on-board care will increasingly become the responsibility of the astronauts for primary management and decision making, terrestrial assets will continue to be paramount in pre-mission screening and planning, as well as prevention, health maintenance and long-term care contingencies. New capabilities and systems that enable progressively more robust and resilient systems and crews will be necessary to reduce risk and increase probability of deep space exploration mission success. An aspiration for EIMO is to develop AI-enhanced solutions for analysis of crew health & performance data and to facilitate clinical decision support for autonomous medical operations. A “system of systems” approach is envisioned whereby EIMO will deploy AI-supported natural language processing and machine learning (ML) techniques to utilize embedded reference databases and real-time data streams [input vectors] from multiple data sources. Constituent input vectors may include environmental controls, countermeasures data, behavioral data, physiologic wearables, point-of-care laboratory tests, personalized medical records, inventory trade space risk assessments, COTS medical databases, and ground support inputs. An ideal AI capability would possess trained fusion algorithms to cross reference input vectors with medical ‘knowledge’ [cultivated database] to stratify relevant data streams for predictive and actionable capabilities. In addition, EIMO will feature mobility, in that it can be accessed and can push/pull data within and between multiple vehicles/habitats. Large amounts and variable sources of data can be leveraged to diagnose, inform treatment strategies, and potentially predict medical events and performance decrements. Inclusion of advanced training tools using extended reality will enable increasingly autonomous medical care to aid a CMO when ground support is unavailable or time-delayed beyond required action window, e.g., emergent medical situations. EIMO CDSS would require very large datasets to train pre-flight and significant amounts of data are needed to support ML via in-flight CDSS operations. An additional challenge will be to find sufficient data to train a model relevant to astronaut demographics. The rapid, accelerating evolution of this field creates a propitious solution space to leverage multi-modal AI through public-private partnership(s). The status of multi-modal AI systems today would preclude their use for long duration missions as they remain unreliable and are subject to “digital hallucinations” and other errors that could pose operational risk. A federated labs structure is being considered to test and optimize data flow from the multiple input vectors leading to field testing in suitable ground/flight analogs. Critical to the success of an EIMO CDSS will be integration and interoperability and success will be defined by a system that can serve as an in-flight medical consult for the CMO providing critical support during medical contingencies. Benefits to terrestrial medicine may be significant as an outflow of the EIMO medical system, particularly for remote areas and communities lacking significant infrastructure, personnel and resources.

Medical Operations↗

NASA NTRSDate not supplied

Testing a Run-Time Assurance Framework Coupled with Integrated Risk Mitigation Capabilities for Autonomous Urban UAS Flights

The In-Time Aviation Safety Management System (IASMS) Concept of Operations (ConOps) envisions new capabilities to monitor, assess, and mitigate flight safety risks. Systems will be tailored to mission type, vehicle/equipage type, operational environment, and safety risk tolerance. Within an IASMS framework, several capabilities may be implemented spanning three operational phases (pre-flight, in-flight, and post-flight/off-line); and consisting of lower level functions and information services which may reside onboard the aircraft, on third-party server(s), and/or on ground/operator station(s). Each capability will be designed to produce and disseminate safety-relevant information; perform detection, diagnosis, and prediction of unsafe situations; and/or execute mitigation actions when hazardous events warrant such changes. This paper focuses on recent testing of airborne capabilities that demonstrate inflight aspects of the overarching concept for autonomous unmanned aircraft systems (UAS) operations in urban environments. A flight test architecture is described that applies run-time assurance principles (e.g., executes independent of the unassured autopilot), real-time risk assessment, and a technique to execute contingencies if necessary either automatically or via pilot intervention. Several tests using small UAS were conducted to verify the assured in-flight risk mitigation capability. The paper draws significantly from a larger NASA technical report and recent prior conference papers, providing additional details. Data is analyzed for two representative flights to illustrate the performance for various sequential and simultaneous hazards used during testing. During each automated flight, several hazards are encountered at various points along the flight path. At each point, the hazard is mitigated by the system, with the vehicle then continuing to subsequent points. The paper concludes with lessons-learned regarding relevant aspects of the overarching IASMS concept and how it may be updated and further advanced in the future.

population activity↗

NASA NTRSDate not supplied

Sensorimotor Countermeasures

Exploration class missions will include multiple transitions between gravitational environments, sometimes after long periods in microgravity, which will impact the neurovestibular system and sensorimotor capabilities. New countermeasures and assessment tools are needed to enhance preflight disorientation training, maintain inflight physical performance, and accelerate recovery following transitions between gravity environments so that crew are enabled to perform critical exploration mission tasks. The Sensorimotor Countermeasures capability area encompasses three projects. 1) The Upright Proprioception Retention via Inflight Training and Evaluation (UPRITE) system is being developed as an in-flight countermeasure that will mitigate the degradation of balance control mechanisms, which will improve post-flight postural stability. The development of such a countermeasure is not simply a matter of adapting a ground-based training program for spaceflight. The way that we control balance in a gravitational environment cannot be duplicated in 0g. Therefore, the UPRITE system challenges proprioception and tactile function using a 0g configuration. The steps to develop the countermeasure have been broken into seven phases: training type, controllable board factors, protocol development, 0g hardware test, training efficacy, ISS hardware demonstration, and countermeasure verification. 2) Unobtrusive Monitoring Tools and Operational Assessments (aka Head/Body Assessments) are being developed to quantify crew member sensorimotor adaptation following gravitational transitions. Three areas are needed in this development 1) explore, develop, and validate unobtrusive monitoring tools, 2) define sensorimotor performance metrics, and 3) explore capabilities to enhance sensorimotor assessment tasks for operational use and validate assessment tasks via high-fidelity analogs. 3) The Spatial Disorientation Trainer is being developed as a portable training capability to simulate the performance of landing and recovery type tasks while experiencing vertigo due to post-flight vestibular alterations. These simulations can be used 1) across research studies investigating the impacts of vestibular disruption on operational performance/assessments, 2) to train astronauts for upcoming spaceflight missions, and 3) to educate space medicine and operational personnel prior to providing post-flight support.

Scott Jonathan Wood↗

NASA NTRSDate not supplied

Development of a Safety Hazards Risk Assessment Tool for Uncrewed Aircraft System Traffic Management during Preflight Planning

Tremendous growth in the uncrewed and remotely piloted vehicle market is expected in low-altitude, uncontrolled airspace, resulting in potential decreases in safety without systems that support monitoring, assessing, and mitigating risk. At NASA, the System-Wide Safety (SWS) project has been developing a suite of data-driven tools to predict hazards so that the potential risks that these hazards pose can be mitigated. Services to predict various hazards have been developed, including battery capacity, proximity to static obstacles, population risks, global positioning system signal strength, radio frequency spectrum interference risk, and vertiport congestion. These services can monitor hazards along a flight path and if any risks posed by these hazards exceed a threshold, the uncrewed aircraft system (UAS) fleet manager can be alerted to mitigate the risk by modifying the flight path, changing the scheduled departure or arrival times, and/or diverting the vehicle to an alternate vertiport. These services were originally developed to monitor and assess risks during flight, but they have been adapted to assess hazard risks prior to departure so that a fleet manager can evaluate the potential risks for a fleet of UAS along their planned flight paths. These services have been integrated into a prototype tool called the Supplemental Data Service Provider-Consolidated Dashboard (SDSP-CD), developed at NASA Ames Research Center. The tool consists of a dashboard which provides a comprehensive overview for a number of risks and a map display that shows the details of the hazards along each flight’s path. Based on the findings from three previous studies, the SDSP-CD has been updated with new design elements and functions. In this paper, we describe lessons learned from the previous studies, changes made to the interface, and the feedback received during a follow-up usability study. Overall, participants reported that there is a substantial benefit of having a fleet manager use a consolidated dashboard to assess hazards for the vehicles in their fleet and to provide situational awareness to potential risks so that they can be mitigated prior to flight. Once the SDSP-CD matures, it will need to be integrated into flight and mission planning tools. Some initial thoughts on how this integration should be accomplished are shared in this paper. Finally, the functional differences between preflight vs. in-flight risk assessment and the differences in fleet manager vs. UAS pilot roles that may require different information and user interactions are discussed.

preflight↗

NASA NTRS1991

Results of Life Sciences DSOs Conducted aboard the Space Shuttle: 1988-1990

Results are presented for a collection of life sciences investigations sponsored by the Space Biomedical Research Institute and Biomedical Research Operations at the NASA Lyndon B. Johnson Space Center and conducted as Detailed Supplementary Objectives (DSOs) on Space Shuttle flights between 1988 and 1990. Reports were grouped into grouped into four primary sections: Orthostatic Function, Neurophysiology, Biomedical Physiology, and Radiation Monitoring. The DSOs included in this report are: - DSO 460: Changes in Total Body Water During Space Flight - DSO 466: Pre- and Postflight Cardiovascular Assessment/Interim Report - DSO 467: Influence of Weightlessness of Baroreflex Function - DSO 459: Otolith Tilt-Translation Reinterpretation - DSO 450: Salivary Cortisol Levels During the Acute Phases of Space Flight - DSO 458: In-flight Pharmacokinetics of Acetaminophen in Saliva - DSO 469A: Low Earth Orbit Radiation Dose Distribution in a Phantom Head - DSO 469B: Active Dosimetric Measurements on Shuttle Flights/Interim Report - DSO 469C: Neutron Spectrum and Dose-Equivalent in Shuttle Flights During Solar Maximum

Carolyn S Leach↗