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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 379 records · Page 21
All sourcesNASA NTRSDOE OSTI
DOE OSTI2025

Quantum-enhanced detection of viral cDNA via luminescence resonance energy transfer using upconversion and gold nanoparticles

Abstract The COVID-19 pandemic has profoundly impacted global economies and healthcare systems, revealing critical vulnerabilities in both. In response, our study introduces a sensitive and highly specific detection method for cDNA, leveraging Luminescence Resonance Energy Transfer (LRET) between upconversion nanoparticles (UCNPs) and gold nanoparticles (AuNPs), and achieves a detection limit of 242 fM for SARS-CoV-2 cDNA. This innovative sensing platform utilizes UCNPs conjugated with one primer and AuNPs with another, targeting the 5′ and 3′ ends of the SARS-CoV-2 cDNA, respectively, enabling precise differentiation of mismatched cDNA sequences and significantly improving detection specificity. Through rigorous experimental analysis, we established a quenching efficiency range from 10.4 % to 73.6 %, with an optimal midpoint of 42 %, thereby demonstrating the superior sensitivity of our method. Our work uses SARS-CoV-2 cDNA as a model system to demonstrate the potential of our LRET-based detection method. This proof-of-concept study highlights the adaptability of our platform for future diagnostic applications. Instrumental validation confirms the synthesis and formation of AuNPs, addressing the need for experimental verification of the preparation of nanomaterial. Our comparative analysis with existing SARS-CoV-2 detection methods revealed that our approach provides a low detection limit and high specificity for target cDNA sequences, underscoring its potential for targeted COVID-19 diagnostics. This study demonstrates the superior sensitivity and adaptability of using UCNPs and AuNPs for cDNA detection, offering significant advances in rapid, accessible diagnostic technologies. Our method, characterized by its low detection limit and high precision, represents a critical step forward in developing next-generation biosensors for managing current and future viral outbreaks. By adjusting primer sequences, this platform can be tailored to detect other pathogens, contributing to the enhancement of global healthcare responsiveness and infectious disease control.

Esmaeili, Shahriar [Institute for Quantum Science ↗
NASA NTRS1983

Performance evaluation of the JPL interim digital SAR processor

The performance of the Interim Digital SAR Processor (IDP) was evaluated. The IDP processor was originally developed for experimental processing of digital SEASAT SAR data. One phase of the system upgrade which features parallel processing in three peripheral array processors, automated estimation for Doppler parameters, and unsupervised image pixel location determination and registration was executed. The method to compensate for the target range curvature effect was improved. A four point interpolation scheme is implemented to replace the nearest neighbor scheme used in the original IDP. The processor still maintains its fast throughput speed. The current performance and capability of the processing modes now available on the IDP system are updated.

Wu, C.↗
NASA NTRS1985

Observations of the polar regions from satellites using active and passive microwave techniques

Observations of the ocean ice, ice sheets, ice edges, and ocean waves in the Antarctic, performed by the Seasat and Nimbus-7 satellites are described. Specific features of the Seasat altimeter, the SAR, the Seasat-A Scatterometer System, and the Scanning Multichannel Microwave Radiometer (SMMR) are discussed, together with the advantages and limitations of each instrument as applied to the study of ice dynamics. The Nimbus-7 SMMR algorithm for calculating sea-ice concentrations is presented. In addition, the Seasat altimeter-derived data on wind speed and wave heights in the Southern Ocean, and on the ice sheets of the Antarctica and Greenland were evaluated.

Swift, C. T.↗
NASA NTRS1987

Imaging radar polarimetry - A status report

The development of imaging radar polarimetry at JPL is considered. Advances in the correlation of polarimetric SAR and in the synthesis of arbitrary polarization are discussed. The capabilities of the polarization workstation are described. Various applications for polarimetric SAR data include: the identification of scatter, the evaluation of scattering theories, the measurement of the roughness of geologic targets, the classification of forest stands, and the characterization of trees within a particular stand. The development and testing of the DC-8 SAR and the SIR-C system are examined.

Held, Daniel N.↗
NASA NTRS1991

Program Processes SAR Data

MacMultiview is interactive software tool for Macintosh II family of computers enabling one to display, and make computations using, polarimetric radar data collected by Jet Propulsion Laboratory's imaging SAR (synthetic-aperture radar) polarimeter system. Provides two basic functions: synthesis of polarimetric images and computation of polarization signatures. System includes single-frequency L-band sensor mounted on NASA CV990 aircraft and its replacement, multifrequency P-, L-, and C-band sensors mounted on NASA DC-8 airplane. Written in C.

Norikane, Lynne↗
NASA NTRS1991

Development of a prototype spatial information processing system for hydrologic research

Significant advances have been made in the last decade in the areas of Geographic Information Systems (GIS) and spatial analysis technology, both in hardware and software. Science user requirements are so problem specific that currently no single system can satisfy all of the needs. The work presented here forms part of a conceptual framework for an all-encompassing science-user workstation system. While definition and development of the system as a whole will take several years, it is intended that small scale projects such as the current work will address some of the more short term needs. Such projects can provide a quick mechanism to integrate tools into the workstation environment forming a larger, more complete hydrologic analysis platform. Described here are two components that are very important to the practical use of remote sensing and digital map data in hydrology. Described here is a graph-theoretic technique to rasterize elevation contour maps. Also described is a system to manipulate synthetic aperture radar (SAR) data files and extract soil moisture data.

Sircar, Jayanta K.↗
NASA NTRS1993

Two microstrip arrays for interferometric SAR applications

Two types of C-band aircraft interferometric Synthetic Aperture Radar (SAR) are being developed at JPL to measure the ocean wave characteristics. Each type requires two identical antennas with each having a long rectangular aperture to radiate fan-shaped beam(s). One type of these radars requires each of its antennas to radiate a broadside beam that will measure the target's cross-track velocity. The other type, having each of its antennas to radiate two off-broadside pointed beams, will allow the measurement of both the cross-track and the along-track velocities of the target. Because flush mounting of the antenna on the aircraft fuselage is desirable, microstrip patch array is selected for these interferometric SAR antennas. To meet the radar system requirement, each array needs a total of 76 microstrip patches which are arranged in a 38 x 2 rectangular aperture with a physical size of 1.6m x 16.5cm. To minimize the insertion loss and physical real estate of this relatively long array, a combined series/parallel feed technique is used. Techniques to suppress cross-pol radiation and to effectively utilize the RF power are also implemented. Cross-pol level of lower than -30 dB from the co-pol peak and low insertion loss of 0.36 dB have been achieved for both types of arrays. For the type of radar that requires two off-braodside pointed beams, a simple phasing technique is used to achieve this dual-beam capability with adequate antenna gain (20 dBi) and sidelobe level (-14 dB). Both radar arrays have been flight tested on aircraft with excellent antenna performance demonstrated.

Huang, J.↗
NASA NTRS1993

The Radar Image Generation (RIG) model

RIG is a modeling system which creates synthetic aperture radar (SAR) and inverse SAR images from 3-D faceted data bases. RIG is based on a physical optics model and includes the effects of multiple reflections. Both conducting and dielectric surfaces can be modeled; each surface is labeled with a material code which is an index into a data base of electromagnetic properties. The inputs to the program include the radar processing parameters, the target orientation, the sensor velocity, and (for inverse SAR) the target angle rates. The current version of RIG can be run on any workstation, however, it is not a real-time model. We are considering several approaches to enable the program to generate realtime radar imagery. In addition to its image generation function, RIG can also generate radar cross-section (RCS) plots as well as range and doppler radar return profiles.

Stenger, Anthony J.↗
NASA NTRS1997

Biweekly Maps of Wind Stress for the North Pacific from the ERS-1 Scatterometer

The European Remote-sensing Satellite (ERS-1) was launched in July 1991 and contained several instruments for observing the Earth's ocean including a wind scatterometer. The scatterometer measurements were processed by the European Space Agency (ESA) and the Jet Propulsion Laboratory (JPL). JPL reprocessed (Freilich and Dunbar, 1992) the ERS-1 backscatter measurements to produced a 'value added' data set that contained the ESA wind vector as well as a set of up to four ambiguities. These ambiguities were further processed using a maximum-likelihood estimation (MLE) and a median filter to produce a 'selected vector.' This report describes a technique developed to produce time-averaged wind field estimates with their expected errors using only scatterometer wind vectors. The processing described in this report involved extracting regions of interest from the data tapes, checking the quality and creating the wind field estimate. This analysis also includes the derivation of biweekly average wind vectors over the North Pacific Ocean at a resolution of 0.50 x 0.50. This was done with an optimal average algorithm temporally and an over-determined biharmonic spline spatially. There have been other attempts at creating gridded wind files from ERS-1 winds, e.g., kriging techniques (Bentamy et al., 1996) and successive corrections schemes (Tang and Liu, 1996). There are several inherent problems with the ERS-1 scatterometer. Since this is a multidisciplinary mission, the satellite is flown in different orbits optimized for each phase of the mission. The scatterometer also shares several sub-systems with the Synthetic Aperture Radar (SAR) and cannot be operated while the SAR is in operation. The scatterometer is also a single-sided instrument and only measures backscatter along the right side of the satellite. The processing described here generates biweekly wind maps during the wktwo years analysis period regardless of the satellite orbit or missing data.

SYNTHETIC APERTURE RADAR↗
NASA NTRS2016

Unlocking the Full Potential of Earth Observation During the 2015 Texas Flood Disaster

Intense rainfall during late April and early May 2015 in Texas and Oklahoma led to widespread and sustained flooding in several river basins. Texas state agencies relevant to emergency response were activated when severe weather then ensued for 6 weeks from 8 May until 19 June following Tropical Storm Bill. An international team of scientists and flood response experts assembled and collaborated with decision-making authorities for user-driven high-resolution satellite acquisitions over the most critical areas; while experimental automated flood mapping techniques provided daily ongoing monitoring. This allowed mapping of flood inundation from an unprecedented number of spaceborne and airborne images. In fact, a total of 27,174 images have been ingested to the USGS Hazards Data Distribution System (HDDS) Explorer, except for the SAR images used. Based on the Texas flood use case, we describe the success of this effort as well as the limitations in fulfilling the needs of the decision-makers, and reflect upon these. In order to unlock the full potential for Earth observation data in flood disaster response, we suggest in a call for action(i) stronger collaboration from the onset between agencies, product developers, and decision-makers;(ii) quantification of uncertainties when combining data from different sources in order to augment information content; (iii) include a default role for the end-user in satellite acquisition planning; and(iv) proactive assimilation of methodologies and tools into the mandated agencies.

Texas↗
NASA NTRS1982

Requirements for a space station

Near-term requirements which will guide the design of a manned space station in near-earth orbit are considered. A primary focus will be establishing a base for astronomical observations which demand long term integration times. Earth observation systems such as the thematic mappers and SAR can be utilized by a free flyer in sunsynchronous orbit. Biological experiments can be carried out only with pressurized modules, ultimately large enough for humans habitation. At first, expendables would be ferried up from earth, while over time the space station would become a closed-loop system. An orbital transfer vehicle is necessary for the repair of satellites stationed in higher energy orbits. The operations of the station would include checking out communications satellites before boost into GEO. Finally, the station would be the final staging point for interplanetary and/or asteroid intercept missions.

Herman, D. H.↗
NASA NTRS1989

Geometric accuracy in airborne SAR images

Uncorrected across-track motions of a synthetic aperture radar (SAR) platform can cause both a severe loss of azimuthal positioning accuracy in, and defocusing of, the resultant SAR image. It is shown how the results of an autofocus procedure can be incorporated in the azimuth processing to produce a fully focused image that is geometrically accurate in azimuth. Range positioning accuracy is also discussed, leading to a comprehensive treatment of all aspects of geometric accuracy. The system considered is an X-band SAR.

Blacknell, D.↗
NASA NTRS1993

Beta Regio rift system on Venus: Geologic interpretation of Magellan images

Magellan SAR images and altimetric data were used to produce a new geologic map of the Northern part of Beta Regio within the frames of C1-30N279 mapsheet. It was part of our contributions into C1-formate geologic mapping efforts. The original map is at 1:8,000,000 scale. The rift structures are typical for Beta Regio on Venus. There are many large uplifted tessera areas on Beta upland. They occupy areas of higher topography. These tessera are partly burried by younger volcanic cover of plain material. These observations show that Beta upland was formed mainly due to lithospheric tectonical uplifting, and only partly was constructed by volcanic activity. A number of rift valleis traverse Beta upland and spread to the surrounding lowlands. The largest rift crosses Beta N to S. Typical width of rifts is 40 to 160 km. Rift valleis in this region are structurally represented by crustal grabens and half-grabens. There are symmetrical and asymmetrical rifts. A lot of them have shoulder uplifts with the relative high up to 0.5-1 km and width 40 to 60 km. Preliminary analysis of the largest rift valley structural cross-sections leads to the conclusion that it originated due to a 5-10 percent crustal extension. The prominent shield volcano - Theia Mons - is located at the center of Beta rift system. It could be considered as the surface manifestation of the upper mantle hot spot. Most of the rift belts are located radially to Theia Mons. The set of these data leads to conclusion that Beta rift system has an 'active-passive' origin. It was formed due to the regional tectonic lithospheric extension. Rifting was accelerated by the upper mantle hot spot located under the center of passive extension (under Beta Regio).

Nikishin, A. M.↗
DOE OSTI2021

AI-driven multiscale simulations illuminate mechanisms of SARS-CoV-2 spike dynamics

We develop a generalizable AI-driven workflow that leverages heterogeneous HPC resources to explore the time-dependent dynamics of molecular systems. We use this workflow to investigate the mechanisms of infectivity of the SARS-CoV-2 spike protein, the main viral infection machinery. Our workflow enables more efficient investigation of spike dynamics in a variety of complex environments, including within a complete SARS-CoV-2 viral envelope simulation, which contains 305 million atoms and shows strong scaling on ORNL Summit using NAMD. We present several novel scientific discoveries, including the elucidation of the spike’s full glycan shield, the role of spike glycans in modulating the infectivity of the virus, and the characterization of the flexible interactions between the spike and the human ACE2 receptor. We also demonstrate how AI can accelerate conformational sampling across different systems and pave the way for the future application of such methods to additional studies in SARS-CoV-2 and other molecular systems.

59 BASIC BIOLOGICAL SCIENCES↗