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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 379 records · Page 21
All sourcesNASA NTRSDOE OSTI
DOE OSTI2025

In vitro activity and in vivo efficacy of omadacycline against Plasmodium species

Abstract Background Doxycycline is currently the only tetracycline-class antibiotic recommended for malaria prophylaxis. Omadacycline, a semisynthetic aminomethylcycline approved for treatment of adults with community-acquired bacterial pneumonia and acute bacterial skin and skin structure infections, has a well-established safety profile. This study evaluated the in vitro activity of omadacycline againstPlasmodium falciparumandPlasmodium cynomolgiand its in vivo efficacy againstPlasmodium bergheiin experimental malaria models to assess its potential as an antimalarial drug. Methods Fluorescence-based assays were used to assess the in vitro blood and liver stage activity of omadacycline and doxycycline againstP. falciparumandP. cynomolgilaboratory clones. In vivo liver and early-stage blood stage efficacy were evaluated in a murine model ofP. bergheiinfection, utilizing in vivo imaging of luciferase-expressingP. berghei(ANKA strain) sporozoites in female albino C57Bl/6 mice. Parasitaemia was monitored by flow cytometry for up to 30 days post-infection. Results Omadacycline demonstrated comparable in vitro activity to doxycycline against both drug-sensitive and drug-resistantP. falciparumclones, while doxycycline showed reduced activity against two drug-resistant clones. Notably, omadacycline exhibited superior anti-schizont activity in theP. cynomolgiliver stage assay. In theP. bergheimurine model, omadacycline was efficacious in both liver and early blood stages compared to the untreated control group, and demonstrated improved survival compared to doxycycline. Conclusions Omadacycline demonstrated enhanced antimalarial efficacy over doxycycline in vitro in liver stage activity and in overcoming resistance in the blood stage, and in survival in an in vivo model ofP. bergheiinfection. These findings support further investigation of omadacycline as a potential candidate for malaria prophylaxis and treatment.

Infectious Diseases↗
DOE OSTI2026

Puget Sound Regional Council 2006 Household Activity Survey

The purpose of the 2006 Puget Sound Regional Council Household Activity Survey was to provide data for travel demand models for the Puget Sound region, for the assessment of current activity and travel patterns, and for the estimation of future activity and travel within the region under various policy scenarios. One important goal of this project is to improve planners' ability to evaluate impacts of future policies and actions on travel patterns and transportation facility use through the development of a database. This database both captures the current status of activity and travel in the region and includes attitudes, preferences, and choices about activities and travel. In the design of the 2006 survey, basic demographics, activities, and tour and travel characteristics were collected for every member (including children) of 4,746 households during a consecutive 48-hour travel period. Vehicle global positioning system (GPS) data were collected from a subsample of 220 of these households, including completed activity/travel diaries for each household member. (Up to three vehicles per household were equipped with GPS units). The final GPS tracking data contained detailed information on the travel paths of 220 households with two vehicles in the same 48-hour period recorded in the diaries.

1Hz data↗
DOE OSTI2025

A new active base of photomultiplier R4125 designed for the PbWO4 calorimeter

This paper presents the design, performance, and results of the radiation tests of an active base for Hamamatsu R4125 photomultiplier tube. The active base was designed at Jefferson Lab and comprises of a high voltage divider and an on-board amplifier. The photomultiplier with the active base is used to detect light from lead tungstate scintillating crystals of the forward electromagnetic calorimeter of the GlueX detector. The active base amplifier allows to operate the tube at lower high voltage and thus to limit the photomultiplier anode current to a few micro ampereres at the maximum counter rate of 1 MHz counter, while retaining the dynamic range of output signals. The performance of calorimeter modules instrumented with the active base was studied using detector prototypes positioned into the beam of photons. The key performance parameters such as the linearity, high-rate capability, and the energy resolution verified that the active base design meets the detector specifications

Somov, Alexander [Thomas Jefferson National Accele↗
DOE OSTI2025

HFIR Activity Workbook Generator (HAWK) User Guide

The HFIR Activity WorkbooK generator (HAWK) is a Python code that automates and streamlines the activity calculation of samples after irradiation in the High Flux Isotope Reactor (HFIR). HAWK’s results provide estimates of the activity and nuclide inventory of irradiated specimens before they are moved to hot cell facilities, where they undergo post-irradiation examination. The samples’ activity results guide the packing of shipping containers and inform the accountable inventories for the hot cell facilities. The toolkit was originally developed by Charles Daily, a former R&D staff member at Oak Ridge National Laboratory (ORNL). As of May 2025, HAWK is developed by the Radiation Transport & HPC Methods Group (Nuclear Energy and Fuel Cycle Division) at ORNL. Figure 1 presents HAWK’s workflow. To use HAWK, users need to: 1. Develop an Excel input workbook (i.e., XLSX extension) containing data from the experiment’s materials, irradiation history (cycles), and irradiation positions. 2. Make minor edits to an existing template JSON file (i.e., auxiliary_data.JSON) and to the Python driver. The driver sets the necessary environment variables, defines the material compositions, and ultimately calls HAWK. Once configured, HAWK runs the Oak Ridge Isotope Generation code (ORIGEN) to calculate the masses, activities, and heat load at the end of irradiation for each isotope in the specimen. ORIGEN is part of SCALE, ORNL’s in-house computational tool for performing nuclear safety and design calculations. Following this step, HAWK postprocesses the results and generates three output workbooks summarizing the activity calculations.

21 SPECIFIC NUCLEAR REACTORS AND ASSOCIATED PLANTS↗
DOE OSTI2026

Investigating the Effects of Bars on Star Formation and Nuclear Activity of Galaxies Using DESI Survey Data

We present a statistical analysis of the connections between galactic bars, star formation, and active galactic nucleus (AGN) activity using 33,201 disk galaxies (0.01 < z < 0.05) from Dark Energy Spectroscopic Instrument Data Release 1 (DESI DR1) cross-matched with Galaxy Zoo DESI. Based on morphological classifications, we identify 3508 strongly barred and 8335 weakly barred systems. We find that barred galaxies exhibit a clear bimodal distribution in color–mass space: weak bars are preferentially found in bluer, lower-mass disks, whereas strong bars are more common in massive, redder systems. Strongly barred galaxies are on average more massive and metal rich than unbarred systems. In addition, strong bars enhance central star formation rates (SFRs) in low-mass galaxies but reduce specific SFRs in massive systems, reflecting a dual role where bars initially trigger central star formation but eventually promote quenching by accelerating gas consumption. In terms of nuclear activity, barred galaxies display a higher incidence of AGN activity. The presence of a bar is also associated with an increased fraction of powerful AGN, with the highest proportions found in strongly barred systems. However, the correlations between AGN activity and detailed bar structural parameters are weak, suggesting that the link between bars and nuclear activity is indirect and regulated by multiple factors. Overall, our results support a scenario in which bars facilitate angular momentum transport and gas inflow, thereby driving central star formation and fueling supermassive black hole accretion while operating alongside other processes that shape galaxy evolution.

Liu, Jianfei [Chinese Academy of Sciences (CAS), B↗
DOE OSTI2025

Activation of propane on Ag–PdO(101) model surfaces

Oxidation of alkanes remains a central challenge in catalysis due to the high activation barriers of C–H bonds and the thermodynamic favorability of complete oxidation. Palladium oxide (PdO), particularly its (101) facet, is known for its high reactivity in alkane oxidation, which is attributed to its coordinatively unsaturated palladium (Pd) and O atoms. In this study, we investigate the effect of silver (Ag) incorporation on the oxidation behavior of propane over PdO(101) using temperature-programmed reaction spectroscopy (TPRS) under controlled conditions. While pristine PdO(101) exhibits complete oxidation of propane with CO₂ and H₂O desorption at high temperatures (approximately 475 K), Ag incorporation induces a new CO₂ desorption peak at significantly lower temperatures (approximately 330 K). This shift is attributed to the formation of new active sites at the Ag–PdO(101) interface. Quantitative analysis reveals that low-temperature activity correlates with Ag coverage, while overall CO₂ production decreases, suggesting a redistribution of reactivity rather than an increase in active surface area. Activation energy estimations using the Redhead method confirm that C–H bond activation becomes more facile at the interface, with a 46 kJ/mol reduction compared to pristine PdO(101). These findings demonstrate that incorporating a less reactive metal such as Ag into PdO surfaces not only modifies the reaction energetics but also enables the design of bimetallic catalysts with improved selectivity for partial oxidation reactions.

Chemistry↗
NASA NTRS1973

The activation energy for creep of columbium /niobium/.

The activation energy for creep of nominally pure columbium (niobium) was determined in the temperature range from 0.4 to 0.75 T sub M by measuring strain rate changes induced by temperature shifts at constant stress. A peak in the activation energy vs temperature curve was found with a maximum value of 160 kcal/mole. A pretest heat treatment of 3000 F for 30 min resulted in even higher values of activation energy (greater than 600 kcal/mole) in this temperature range. The activation energy for the heat-treated columbium (Nb) could not be determined near 0.5 T sub M because of unusual creep curves involving negligible steady-state creep rates and failure at less than 5% creep strain. It is suggested that the anomalous activation energy values and the unusual creep behavior in this temperature range are caused by dynamic strain aging involving substitutional atom impurities and that this type of strain aging may be in part responsible for the scatter in previously reported values of activation energy for creep of columbium (Nb) near 0.5 T sub M.

Klein, M. J.↗
NASA NTRS1974

Flutter suppression and gust alleviation using active controls

The effects of active controls on the suppression of flutter and gust alleviation of two different types of subsonic aircraft (the Arava, twin turboprop STOL transport, and the Westwind twin-jet business transport) are investigated. The active controls are introduced in pairs which include, in any chosen wing strip, a leading-edge (LE) control and a trailing-edge (TE) control. Each control surface is allowed to be driven by a combined linear-rotational sensor system, located on the activated strip. The control law, which translates the sensor signals into control surface rotations, is based on the concept of aerodynamic energy. The results indicate the extreme effectiveness of the active systems in controlling flutter. A single system spanning 10% of the wing semispan made the Arava flutter-free, and a similar active system, for the Westwind aircraft, yielded a reduction of 75% in the maximum bending moment of the wing and a reduction of 90% in the acceleration of the cg of the aircraft. Results for simultaneous activation of several LE - TE systems are presented. Further work needed to bring the investigation to completion is also discussed.

Nissim, E.↗
NASA NTRS1973

The evolution of prominences and their relationship to active centers /A Review/

A necessary condition for the formation of prominences is established where components of the magnetic field of opposite sign lie juxtaposed. This condition is sometimes recognizable prior to the formation of prominences in active centers and between adjacent active centers in H-alpha by paths of fibrils aligned nearly end to end. Prominences are usually not found in active regions until they are about 4 days old. After this time, the number of prominences appears to be a function of the large-scale complexities in the magnetic field pattern whether these are a result of emerging flux, the merging of adjacent active centers, or the coalescing of remnant fields of active centers. Prominences may disappear by the slow or rapid flow of mass into the chromosphere or by the more violent eruptives. The formation of new active centers has been associated with the eruption of some filaments related to weak chromospheric fields.

Martin, S. F.↗
NASA NTRS1976

JPL Activated Carbon Treatment System (ACTS) for sewage

An Activated Carbon Treatment System (ACTS) was developed for sewage treatment and is being applied to a one-million gallon per day sewage treatment pilot plant in Orange County California. Activities reported include pyrolysis and activation of carbon-sewage sludge, and activated carbon treatment of sewage to meet ocean discharge standards. The ACTS Sewage treatment operations include carbon-sewage treatment, primary and secondary clarifiers, gravity (multi-media) filter, filter press dewatering, flash drying of carbon-sewage filter cake, and sludge pyrolysis and activation. Tests were conducted on a laboratory scale, 10,000 gallon per day demonstration plant and pilot test equipment. Preliminary economic studies are favorable to the ACTS process relative to activated sludge treatment for a 175,000,000 gallon per day sewage treatment plant.

Source record↗
NASA NTRS1976

Application of the aerodynamic energy concept to flutter suppression and gust alleviation by use of active controls

The effects of active controls on flutter suppression and gust alleviation of the Arava twin turboprop STOL transport and the Westwind twinjet business transport are investigated. The active control surfaces are introduced in pairs which include, in any chosen wing strip, a 20-percent chord leading-edge control and a 20-percent chord trailing-edge control. Each control surface is driven by a combined linear-rotational sensor system located on the activated strip. The control law is based on the concept of aerodynamic energy and utilizes previously optimized control law parameters based on two-dimensional aerodynamic theory. The best locations of the activated system along the span of the wing are determined for bending-moment alleviation, reduction in fuselage accelerations, and flutter suppression. The effectiveness of the activated system over a wide range of maximum control deflections is also determined. Two control laws are investigated. The first control law utilizes both rigid-body and elastic contributions of the motion. The second control law employs primarily the elastic contribution of the wing and leads to large increases in the activated control effectiveness as compared with the basic control law. The results indicate that flutter speed can be significantly increased (over 70 percent increase) and that the bending moment due to gust loading can be almost totally eliminated by a control system of about 10 to 20 percent span with reasonable control-surface rotations.

Nissim, E.↗
NASA NTRS1977

Preliminary investigation of a sealed, remotely activated silver-zinc battery

Methods necessary to provide a remotely activated, silver zinc battery capable of an extended activated stand while in a sealed condition were investigated. These requirements were to be accomplished in a battery package demonstrating an energy density of at least 35 watt hours per pound. Several methods of gas suppression were considered in view of the primary nature of this unit and utilized the electroplated dendritic zinc electrode. Amalgamation of the electrode provided the greatest suppression of gas at the zinc electrode. The approach to extending the activated stand capability of the remotely activated battery was through evaluation of three basic methods of remote, multi-cell activation; 1) the electrolyte manifold, 2) the gas manifold and 3) the individual cell. All three methods of activation can be incorporated into units which will meet the minimum energy density requirement.

Wheat, C. G.↗
NASA NTRS1977

Open magnetic fields in active regions

Soft X-ray images and magnetograms of several active regions and coronal holes are examined which support the interpretation that some of the dark X-ray gaps seen between interconnecting loops and inner cores of active regions are foot points of open field lines inside the active regions. Characteristics of the investigated dark gaps are summarized. All the active regions with dark X-ray gaps at the proper place and with the correct polarity predicted by global potential extrapolation of photospheric magnetic fields are shown to be old active regions, indicating that field opening is accomplished only in a late phase of active-region development. It is noted that some of the observed dark gaps probably have nothing in common with open fields, but are either due to the decreased temperature in low-lying portions of interconnecting loops or are the roots of higher and less dense or cooler loops.

Svestka, Z.↗
NASA NTRS1979

Accelerated development and flight evaluation of active controls concepts for subsonic transport aircraft

The flight test of an active load alleviation/extended span for the L-1011 wide-body transport aircraft, and piloted simulation work leading to use of active stability augmentation with a small tail and aft center of gravity are reported. The extended span showed the expected cruise drag reduction of 3%. The small tail is expected to reduce cruise drag by another 3%, and eventual use of more aft center of gravity with active stability augmentation will provide further fuel savings. The active load alleviation functions included maneuver load control (MLC) and elastic mode suppression (EMS), using symmetric motions of the outboard ailerons to reduce wing bending loads in maneuvers or long-term up- or down-drafts (MLC), and to damp wing bending motions in turbulence (EMS). A gust load alleviation function using the active horizontal tail to provide airplane pitch damping in turbulence was found unnecessary. The piloted simulation tests evaluated criteria for augmentation-on and augmentation-off flying qualities. of a simple pitch control law was verified at neutral static margin. The simulation tasks established the basis for follow-on construction and flight testing of a small tail with active stability augmentation.

Source record↗
NASA NTRS1979

Review of selected geomagnetic activity indices

Magnetic activity indexes are reviewed. Classifications of magnetograms from single observatories and the global range of potential associated with the equivalent currents which could have produced the variations monitored at a large array of recording sides are addressed. Principal magnetic activity indexes discussed include: the auroral electrojet index and its associated indexes (AU, AL and AO) useful for auroral zone studies; the Kp, ap, aa and am indexes which are measures of midlatitude geomagnetic activity; and the Dst index of magnetic activity recorded at low latitudes. It is concluded that geomagnetic activity indexes are useful in studies of the interaction between solar activity, the interplanetary magnetic field and solar wind, the magnetosphere, ring current, field aligned currents, and ionospheric currents.

Allen, J. H.↗
NASA NTRS1981

A global tectonic activity map with orbital photographic supplement

A three part map showing equatorial and polar regions was compiled showing tectonic and volcanic activity of the past one million years, including the present. Features shown include actively spreading ridges, spreading rates, major active faults, subduction zones, well defined plates, and volcanic areas active within the past one million years. Activity within this period was inferred from seismicity (instrumental and historic), physiography, and published literature. The tectonic activity map was used for planning global geodetic programs of satellite laser ranging and very long base line interferometry and for geologic education.

Lowman, P. D., Jr.↗
NASA NTRS1982

Studies of neutron and proton nuclear activation in low-Earth orbit

The expected induced radioactivity of experimental material in low Earth orbit was studied for characteristics of activating particles such as cosmic rays, high energy Earth albedo neutrons, trapped protons, and secondary protons and neutrons. The activation cross sections for the production of long lived radioisotopes and other existing nuclear data appropriate to the study of these reactions were compiled. Computer codes which are required to calculate the expected activation of orbited materials were developed. The decreased computer code used to predict the activation of trapped protons of materials placed in the expected orbits of LDEF and Spacelab II. Techniques for unfolding the fluxes of activating particles from the measured activation of orbited materials are examined.

Laird, C. E.↗
NASA NTRS1983

Magnetic fields and activity of the sun and stars - An overview

Recent work on the observation and theory of solar and stellar magnetic field activity and its relation to stellar activity is reviewed, emphasizing those aspects relevant to the problem of activity of red dwarf stars. New observational facts relevant to understanding the root cause of stellar surface activity are summarized and theoretical questions concerning the underlying physical basis for the observed correlations between stellar activity, rotation, and magnetic fields are addressed. These include dyanamo theory and the rotation-activity connection as well as flux tube dynamics and plasma heating.

Rosner, R.↗