Search NASA⌕ Search

SEARCH · Search NASA

Results for “Proton structure”

Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 397 records · Page 22
All sourcesNASA NTRSDOE OSTI
NASA NTRS1997

Structure of an anti-HIV-1 hammerhead ribozyme complex with a 17-mer DNA substrate analog of HIV-1 gag RNA and a mechanism for the cleavage reaction: 750 MHz NMR and computer experiments

The structure of an anti-HIV-1 ribozyme-DNA abortive substrate complex was investigated by 750 MHz NMR and computer modeling experiments. The ribozyme was a chimeric molecule with 30 residues-18 DNA nucleotides, and 12 RNA residues in the conserved core. The DNA substrate analog had 17 residues. The chimeric ribozyme and the DNA substrate formed a shortened ribozyme-abortive substrate complex of 47 nucleotides with two DNA stems (stems I and III) and a loop consisting of the conserved core residues. Circular dichroism spectra showed that the DNA stems assume A-family conformation at the NMR concentration and a temperature of 15 degrees C, contrary to the conventional wisdom that DNA duplexes in aqueous solution populate entirely in the B-form. It is proposed that the A-family RNA residues at the core expand the A-family initiated at the core into the DNA stems because of the large free energy requirement for the formation of A/B junctions. Assignments of the base H8/H6 protons and H1' of the 47 residues were made by a NOESY walk. In addition to the methyl groups of all T's, the imino resonances of stems I and III and AH2's were assigned from appropriate NOESY walks. The extracted NMR data along with available crystallographic data, were used to derive a structural model of the complex. Stems I and III of the final model displayed a remarkable similarity to the A form of DNA; in stem III, a GC base pair was found to be moving into the floor of the minor groove defined by flanking AT pairs; data suggest the formation of a buckled rhombic structure with the adjacent pair; in addition, the base pair at the interface of stem III and the loop region displayed deformed geometry. The loop with the catalytic core, and the immediate region of the stems displayed conformational multiplicity within the NMR time scale. A catalytic mechanism for ribozyme action based on the derived structure, and consistent with biochemical data in the literature, is proposed. The complex between the anti HIV-1 gag ribozyme and its abortive DNA substrate manifests in the detection of a continuous track of A.T base pairs; this suggests that the interaction between the ribozyme and its DNA substrate is stronger than the one observed in the case of the free ribozyme where the bases in stem I and stem III regions interact strongly with the ribozyme core region (Sarma, R. H., et al. FEBS Letters 375, 317-23, 1995). The complex formation provides certain guidelines in the design of suitable therapeutic ribozymes. If the residues in the ribozyme stem regions interact with the conserved core, it may either prevent or interfere with the formation of a catalytically active tertiary structure.

NASA Discipline Exobiology↗
NASA NTRS2007

Measurement of Damage Profiles from Solar Wind Implantation

NASA's Genesis Mission launched from Cape Canaveral in August of 2001 with the goal of collecting solar wind in ultra-pure materials. The samples were returned to Earth more than three years later for subsequent analysis. Although the solar wind is comprised primarily of protons, it also contains ionized species representing the entire periodic table. The Genesis mission took advantage of the natural momentum of these ionized species to implant themselves in specialized collectors including single crystal Si and SiC. The collectors trapped the solar wind species of interest and sustained significant damage to the surface crystal structure as a result of the ion bombardment. In this work, spectroscopic ellipsometry has been used to evaluate the extent of this damage in Si and SiC samples. These results and models are compared for artificially implanted samples and pristine non-flight material. In addition, the flown samples had accumulated a thin film of molecular contamination as a result of outgassing in flight, and we demonstrate that this layer can be differentiated from the material damage. In addition to collecting bulk solar wind samples (continuous exposure), the Genesis mission actually returned silicon exposed to four different solar wind regimes: bulk, high speed, low speed, and coronal mass ejections. Each of these solar wind regimes varies in energy, but may vary in composition as well. While determining the composition is a primary goal of the mission, we are also interested in the variation in depth and extent of the damage layer as a function of solar wind regime. Here, we examine flight Si from the bulk solar wind regime and compare the results to both pristine and artificially implanted Si. Finally, there were four samples which were mounted in an electrostatic "concentrator" designed to reject a large fraction (>85%) of incoming protons while enhancing the concentration of ions mass 4-28 amu by a factor of at least 20. Two of these samples were single crystal 6H silicon carbide. (The others were polycrystalline CVD diamond and amorphous carbon that were not examined in the work.) The ion damaged SiC samples from the concentrator were studied in comparison to the flight Si from the bulk array to understand differences in the extent of the damage.

McNamara, K. M.↗
NASA NTRS1972

Silicon solar cell development and radiation effects study for low temperature and low illumination intensity operation, volume 2

The results are presented of a study to determine the effect of in-situ proton irradiation upon low temperature, low intensity performance of several cell types. The cell types were selected in an attempt to distinguish variations in temperature-dependent radiation resistance which could be attributed to the n-p or p-n structure, diffused or implanted junctions, crucible grown or float-zone type base material, and high or low base resistivity. The results indicate that while expected variations of performance occur at room temperature, all cell types degrade more or less similarly at lower temperatures with normalized degradation becoming increasingly rapid as temperature is reduced. Recommendations for an optimized cell for Jupiter probe use are included along with a definition of the testing required on these cells to insure good performance characteristics.

Kirkpatrick, A. R.↗
NASA NTRS1992

Ulysses particle observations of the March 1991 solar flare events

Observations of energetic ions from the COSPIN instrument on the Ulysses spacecraft at 2.5 AU during the March 1991 series of solar flare events arae presented. The intensity profiles observed during this sequence of events were affected both by the presence of interplanetary shocks and large-scale discontinuities in the magnetic field, the low-energy (about 1 MeV) protons being influenced mainly by the shocks and the discontinuities, and the high-energy (about 100 MeV) protons by the discontinuities. The first shock observed at Ulysses was followed by several discontinuities and a Coronal Mass Ejection (CME) which were probably moving with the shock. Particles following this shock were prevented from propagating freely into the heliosphere by the structure moving with the shock, and were carried along with it. A second shock was followed by a region containing bi-directional particle anisotropies. A subsequent enhancement of low-energy particles suggests the passage of another shock. This was followed by a slow intensity decay which coincided with a second CME and where bi-directional particle anisotropies were again observed.

Sanderson, T. R.↗
NASA NTRS1994

An initiation-promotion model of tumour prevalence from high-charge and energy radiations

A repair/misrepair kinetic model for multiple radiation-induced lesions (mutation inactivation) is coupled to a two-mutation model of initiation-promotion in tissue to provide a parametric description of tumour prevalence in the mouse Harderian gland from high-energy and charge radiations. Track-structure effects are considered using an action-cross section model. Dose-response curves are described for gamma rays and relativistic ions, and good agreement with experiment is found. The effects of nuclear fragmentation are also considered for high-energy proton and alpha-particle exposures. The model described provides a parametric description of age-dependent cancer induction for a wide range of radiation fields. Radiosensitivity parameters found in the model for an initiation mutation (sigma 0 = 7.6 x 10(-10) cm2 and D0 = 148.0 Gy) are somewhat different than previously observed for neoplastic transformation of C3H10T1/2 cell cultures (sigma 0 = 0.7 x 10(-10) cm2 and D0 = 117.0 Gy). We consider the two hypotheses that radiation acts solely as an initiator or as both initiator and promoter and make model calculations for fractionation exposures from gamma rays and relativistic Fe ions. For fractionated Fe exposures, an inverse-dose-rate effect is provided by a promotion hypothesis with an increase of 30% or more, dependent on the dose level and fractionation schedule, using a mutation rate for promotion similar to that of single-gene mutations.

NASA Discipline Radiation Health↗
NASA NTRS1992

The rhodopsins: structure and function. Introduction

Nature makes use of the propensity of retinal for light-dependent double-bond isomerization in a number of systems and in a variety of ways. The common theme for light receptors based on this kind of chemistry is that (1) the retinal is bound in most cases to a small membrane protein via a protonated lysine-retinal Schiff base, (2) the absorption maximum in the visible is tuned to a suitable wavelength largely by electrostatic interaction with polar protein residues, and (3) the light-induced bond rotations and strains in the retinal set off reaction chains during which at least part of the excess free energy acquired is transferred to the protein and causes pK shifts of acidic residues and/or backbone conformational changes. The physiological consequence of the process initiated by absorption of light is either the activation of an information transfer chain (sensory and visual rhodopsins) or energy transduction which drives the electrogenic movement of ions across the membrane (ion-motive rhodopsins). Rhodopsins with these functions occur in bacteria and in higher organisms; from an evolutionary standpoint they are not related to one another. Nevertheless, all of these proteins are remarkably similar and form a distinct family.

NASA Discipline Number 52-30↗
NASA NTRS2017

Kinetic Scale Structure of Low-Frequency Waves and Fluctuations

The dissipation of solar wind turbulence at kinetic scales is believed to be important for the heating of the corona and for accelerating the wind. The linear Vlasov kinetic theory is a useful tool for identifying various wave modes, including kinetic Alfven, fast magnetosonic/whistler, and ion-acoustic (or kinetic slow), and their possible roles in the dissipation. However, the kinetic mode structure in the vicinity of ion-cyclotron modes is not clearly understood. The present paper aims to further elucidate the structure of these low-frequency waves by introducing discrete particle effects through hybrid simulations and Klimontovich formalism of spontaneous emission theory. The theory and simulation of spontaneously emitted low-frequency fluctuations are employed to identify and distinguish the detailed mode structures associated with ion-Bernstein modes versus quasi-modes. The spontaneous emission theory and simulation also confirm the findings of the Vlasov theory in that the kinetic Alfven waves can be defined over a wide range of frequencies, including the proton cyclotron frequency and its harmonics, especially for high-beta plasmas. This implies that these low-frequency modes may play predominant roles even in the fully kinetic description of kinetic scale turbulence and dissipation despite the fact that cyclotron harmonic and Bernstein modes may also play important roles in wave-particle interactions.

waves↗
NASA NTRS1998

Investigation of Coronal Large Scale Structures Utilizing Spartan 201 Data

Two telescopes aboard Spartan 201, a small satellite has been launched from the Space Shuttles, on April 8th, 1993, September 8th, 1994, September 7th, 1995 and November 20th, 1997. The main objective of the mission was to answer some of the most fundamental unanswered questions of solar physics-What accelerates the solar wind and what heats the corona? The two telescopes are 1) Ultraviolet Coronal Spectrometer (UVCS) provided by the Smithsonian Astrophysical Observatory which uses ultraviolet emissions from neutral hydrogen and ions in the corona to determine velocities of the coronal plasma within the solar wind source region, and the temperature and density distributions of protons and 2) White Light Coronagraph (WLC) provided by NASA's Goddard Space Flight Center which measures visible light to determine the density distribution of coronal electrons within the same region. The PI has had the primary responsibility in the development and application of computer codes necessary for scientific data analysis activities, end instrument calibration for the white-light coronagraph for the entire Spartan mission. The PI was responsible for the science output from the WLC instrument. PI has also been involved in the investigation of coronal density distributions in large-scale structures by use of numerical models which are (mathematically) sufficient to reproduce the details of the observed brightness and polarized brightness distributions found in SPARTAN 201 data.

Guhathakurta, Madhulika↗
NASA NTRS1984

Structure of the November 12, 1978, quasi-parallel interplanetary shock

The jump in plasma parameters exhibited by the intense interplanetary shock event of Nov. 12, 1978 is analyzed using ISEE 1, 2 and 3 data. Magnetic and electric field measurements indicated that the shock magnetic field profile was similar to the earth bow shock profile. Data on the electron and proton densities, temperatures, bulk velocities and alpha particles showed a steady electron temperature increase across the shock on a 12 earth radii scale. The upstream and downstream flow parameters are found to be within 10 percent of Rankin-Hugoniot jump conditions. The shock moved at 614 km/sec and had three dissipative scales, one a few Larmor radii determined by the magnetic field jump, a second 10 earth radii correlated with the electron equilibrium and the other 30 earth radii connected to the energetic proton foreshock.

Kennel, C. F.↗
NASA NTRS1972

Conclusion

A set of models was established for the Jupiter electron and proton trapped radiation belt which could be used in the determination of outer planets mission spacecraft design requirements. Two models each for the electron and proton components evolved: a nominal or best estimate model, and an upper limit model. The models are described by presenting the assumptions that were agreed to be then best basis for the models at this time, and then describing the models which were structured in the time available. The discussion which took place at the final session is also presented.

Beck, A. J., Jr.↗
NASA NTRS1980

Variability of plasma sheet dynamics

IMP 7 observations of plasma sheet structure and dynamics made during a 24-h period in which the satellite traversed the tail plasma sheet at a radial distance of 35 earth radii and remained within 2 earth radii of the expected position at the neutral sheet and in which at least five substorms occured on the ground are presented. High-time-resolution measurements of the magnetic field, plasma flow and greater than 50-keV protons obtained by the satellite and ground-based magnetic measurements are discussed for a 4-hr interval in which two small substorms occurred, a 6-hr geomagnetically quiet interval in which moderate variable plasma flows were observed, a very rapid, smooth neutral sheet crossing and earthward plasma flow during the expansion phase of a small substorm, a moderate-size substorm in which a prolonged interval of field-aligned tailward flow commenced at onset, a strong tailward and dawnward flow burst in an interval between substorms and a large substorm in which strong tailward flow was observed. Observations indicate the significant distortion of the tail field, possibly by plasma flow stresses, a neutral sheet structure occasionally resembling the hydromagnetic rotational discontinuity and a high level of magnetic turbulence during an earthward plasma flow which may contribute towards plasma sheet dissipation.

Coroniti, F. V.↗
NASA NTRS2023

Direct Measurement of the Spectral Structure of Cosmic-Ray Electrons+Positrons in the Tev Region With Calet on the International Space Station

Detailed measurements of the spectral structure of cosmic-ray electrons and positrons from 10.6 GeV to 7.5 TeV are presented from over 7 years of observations with the CALorimetric Electron Telescope (CALET) on the International Space Station. The instrument, consisting of a charge detector, an imaging calorimeter, and a total absorption calorimeter with a total depth of 30 radiation lengths at normal incidence and a fine shower imaging capability, is optimized to measure the all-electron spectrum well into the TeV region. Because of the excellent energy resolution (a few percent above 10 GeV) and the outstanding e/p separation (10 5 ), CALET provides optimal performance for a detailed search of structures in the energy spectrum. The analysis uses data up to the end of 2022, and the statistics of observed electron candidates has increased more than 3 times since the last publication in 2018. By adopting an updated boosted decision tree analysis, a sufficient proton rejection power up to 7.5 TeV is achieved, with a residual proton contamination less than 10%. The observed energy spectrum becomes gradually harder in the lower energy region from around 30 GeV, consistently with AMS-02, but from 300 to 600 GeV it is considerably softer than the spectra measured by DAMPE and Fermi-LAT. At high energies, the spectrum presents a sharp break around 1 TeV, with a spectral index change from −3.15 to −3.91, and a broken power law fitting the data in the energy range from 30 GeV to 4.8 TeV better than a single power law with 6.9 sigma significance, which is compatible with the DAMPE results. The break is consistent with the expected effects of radiation loss during the propagation from distant sources (except the highest energy bin). We have fitted the spectrum with a model consistent with the positron flux measured by AMS-02 below 1 TeV and interpreted the electron+positron spectrum with possible contributions from pulsars and nearby sources. Above 4.8 TeV, a possible contribution from known nearby supernova remnants, including Vela, is addressed by an event-by-event analysis providing a higher proton-rejection power than a purely statistical analysis.

O. Adriani↗
NASA NTRS1987

Lunar and Planetary Science Conference, 17th, Houston, TX, Mar. 17-21, 1986, Proceedings. Part 2

The topics discussed in this volume include lunar endogenic rocks and processes; lunar regoliths and breccias; the terrestrial planets; shergottites; primitive materials, exposure, and atmospheres; and impacts and crater tectonics. Papers are presented on the petrology and geochemistry of alkali gabbronorites from lunar breccia 67975; the formation of Apollo 17 orange and black glass beads; mixing levels, the Apennine Front soil component, and compositional trends in the Apollo 15 soils; the meteorite component of Apollo 16 noritic impact melt breccias; and constraints on the lithospheric structure of Venus from mechanical models and tectonic surface features. Consideration is also given to a fractal interpretation of topography and geoid spectra on the earth, moon, Venus, and Mars; rare earth patterns in shergottite phosphates and residues; nuclide production by primary cosmic-ray protons; gas chromatographic instrumentation for the analysis of aerosols and gases in Titan's atmosphere; and finite-element models of non-Newtonian crater relaxation.

Ryder, Graham↗
NASA NTRS1988

Resonance absorption of Alfven waves at comet-solar wind interaction regions

The interaction of the low-frequency (0.01 Hz) MHD waves, observed upstream of comets, with the structured plasma near the cometary bow wave is examined. It is suggested that the waves undergo resonant absorption due to either ambient density gradients or localized shear in the background magnetic field. The absorption process can give rise to rapid heating of the solar wind protons, in agreement with observations from Comet Halley. Since the free energy for the generation of MHD waves came from deceleration (without accompanying heating) of the solar wind protons during the pick-up of cometary ions, the subsequent reabsorption of the energy is equivalent to a nonlocal transformation of ordered to random energy and can be described as nonlocal viscosity.

Sharma, A. S.↗
NASA NTRS2000

Molecular Simulations in Astrobiology

One of the main goals of astrobiology is to understand the origin of cellular life. The most direct approach to this problem is to construct laboratory models of protocells. Such efforts, currently underway in the NASA Astrobiology Program, are accompanied by computational studies aimed at explaining self-organization of simple molecules into ordered structures that are capable of performing protocellular functions. Many of these functions, such as importing nutrients, capturing energy and responding to changes in the environment, are carried out by proteins bound to membranes. We use computer simulations to address the following questions about these proteins: (1) How do small proteins self-organize into ordered structures at water-membrane interfaces and insert into membranes? (2) How do peptides form membrane-spanning structures (e.g. channels)? (3) By what mechanisms do such structures perform their functions? The simulations are performed using the molecular dynamics method. In this method, Newton's equations of motion for each atom in the system are solved iteratively. At each time step, the forces exerted on each atom by the remaining atoms are evaluated by dividing them into two parts. Short-range forces are calculated in real space while long-range forces are evaluated in reciprocal space, using a particle-mesh algorithm which is of order O(NInN). With a time step of 2 femtoseconds, problems occurring on multi-nanosecond time scales (10(exp 6)-10(exp 8) time steps) are accessible. To address a broader range of problems, simulations need to be extended by three orders of magnitude, which requires algorithmic improvements and codes scalable to a large number of processors. Work in this direction is in progress. Two series of simulations are discussed. In one series, it is shown that nonpolar peptides, disordered in water, translocate to the nonpolar interior of the membrane and fold into helical structures (see Figure). Once in the membrane, the peptides exhibit orientational flexibility with changing conditions, which may have provided a mechanism of transmitting signals between the protocell and its environment. In another series of simulations, the mechanism by which a simple protein channel efficiently mediates proton transport across membranes was investigated. This process is a key step in cellular bioenergetics. In the channel under study, proton transport is gated by four histidines that occlude the channel pore. The simulations identify the mechanisms by which protons move through the gate.

Pohorille, Andrew↗
NASA NTRSDate not supplied

Integration of Advanced Structures and Materials Technologies for a Robust Lunar Habitat

NASA’s Artemis program plans to have a sustainable lunar base deployed on the Moon by 2028. The base calls for a foundation surface habitat that can support a crew of four members for a minimum mission duration of 28-days. The lack of a magnetic field and significant lunar atmosphere extends the lifetime of secondary radiation emitted from metallic structures, which is a health hazard for exposed astronauts. Integration of non-metallic structural materials into surface habitat design may alleviate some of these concerns. Additionally, it is favorable for the structure to be collapsible for transportation to optimize payload volume, mass efficiency, and monetary constraints. As a result, inflatable structures are being investigated due to their improved packing efficiency at launch, optimal mass-to-volume ratio, and large surface area that can efficiently disperse structural loads and heat. Currently, only two inflatable airlocks have been deployed in space. Thus, there is a significant need to advance technologies associated with inflatable structures to provide greater options for future missions, i.e., Artemis and beyond. This study focused on the inflatable lunar habitat applications of emerging NASA Langley Research Center (LaRC) technologies and their required development steps to become space qualified. The Bowling Habitat architecture was generated from 13 of these NASA LaRC technologies, five of which were deemed critical, five determined as enhancing technologies, and three were classified as transformational technologies for the Artemis program. To address the payload constraints, the study also considered a tentative timeline that aligned with the current Artemis schedule for transporting the Bowling Habitat to the Moon. Ultimately, the Bowling Habitat mainly addressed the structural needs of an inflatable lunar habitat, meaning that major areas pertaining to the life-style aspects of the habitat must be improved. Areas include, but are not limited to, hard connection points, the monitoring of human health, and extra radiation protection for solar proton events.

Inflatable Habitat↗
NASA NTRS2023

Parker Solar Probe Observations of High Plasma β Solar Wind From the Streamer Belt

In general, slow solar wind from the streamer belt forms a high plasma β equatorial plasma sheet around the heliospheric current sheet (HCS) crossing, namely, the heliospheric plasma sheet (HPS). Current Parker Solar Probe (PSP) observations show that the HCS crossings near the Sun could be full or partial current sheet (PCS) crossings, and they share some common features but also have different properties. In this work, using the PSP observations from encounters 4–10, we identify streamer belt solar wind from enhancements in plasma β, and we further use electron pitch angle distributions to separate it into HPS solar wind around the full HCS crossings and PCS solar wind in the vicinity of PCS crossings. Based on our analysis, we find that the PCS solar wind has different characteristics as compared with HPS solar wind: (a) the PCS solar wind could be non-pressure-balanced structures rather than magnetic holes, and the total pressure enhancement mainly results from the less reduced magnetic pressure; (b) some of the PCS solar wind is mirror-unstable; and (c) the PCS solar wind is dominated by very low helium abundance but varied alpha–proton differential speed. We suggest that the PCS solar wind could originate from coronal loops deep inside the streamer belt, and it is pristine solar wind that still actively interacts with ambient solar wind; thus, it is valuable for further investigations of the heating and acceleration of slow solar wind.

Slow solar wind↗