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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 397 records · Page 22
All sourcesNASA NTRSDOE OSTI
NASA NTRS2025

Countermeasures for Mitigation of Sensorimotor Decrements Following Head-Down Tilt Bed Rest

BACKGROUND Astronauts experience postflight disturbances in postural and locomotor control due to sensorimotor adaptations during spaceflight. These alterations may have adverse consequences if a rapid egress is required after landing. Although exercise is partially effective for mitigating cardiovascular and muscular deconditioning, additional countermeasures are needed to further preserve sensorimotor function. Proprioception training and electrical muscle stimulation (EMS) are two promising in-flight countermeasures. Since prolonged head down tilt bed rest (HDTBR) is a spaceflight analog for body unloading and causes postural and locomotor control decrements that parallel those observed after spaceflight, it can be used to facilitate the development of these countermeasures. METHODS This study will determine the effects of proprioception training and EMS on functional task performance and sensorimotor function following 60 days of 6° HDTBR. Subjects will be randomly assigned to one of four groups: 1) an EMS arm, 2) a proprioception training arm, 3) an exercise plus proprioceptive training arm, and 4) a control arm. The EMS countermeasure will include daily bilateral stimulation of selected bilateral lower extremity muscles (30 minutes per session). Proprioception training will be performed three days per week (25 minutes per session) consisting of body-loaded postural tasks in the horizontal position on an air bearing sled. Exercise training will mimic current protocols used on the International Space Station, but treadmill aerobic exercise will be replaced with additional cycling aerobic exercise. Primary outcome measures will include pre- and post- HDTBR functional tests that require high demand for dynamic control of postural stability. Secondary measures will be used to explore key physiological changes that underlie countermeasure benefits. All HDTBR and data collection activities will be completed by the German Aerospace Center (DLR) at the :envihab facility. Given the constrained samples size, a Bayesian modelling approach will be used to quantify the probability that there is an effect of a given magnitude. HARDWARE AND PROTOCOL DEVELOPMENT Final hardware modifications and protocol developments were completed in preparation for Campaign 1, which began in September 2024. These included shipment, setup, and operator training for the transportable gravity bed, horizontal squat device, foam obstacle course, EMS devices, leg dexterity system, foot sole skin sensitivity system, and Radiofrequency Echographic Multi Spectrometry (REMS) ultrasound device. In addition, specialized protocols were developed for data collection using DLR’s equipment, including muscle morphology magnetic resonance imaging (MRI), optical coherence tomography, venous blood flow MRI and ultrasound, muscle ultrasound and impedance, and skin blood flow ultrasound. We will present early data from the first campaign, which concluded in November, 2024. These will be compared with previous data from the recent 30-day HDTBR campaigns (Spaceflight associated neuro-ocular syndrome countermeasures (SANS-CM)) conducted at DLR. RELEVANCE The deliverable from this project will be proof-of-concept sensorimotor countermeasure designs for functional task performance with full assessment of efficacy in a spaceflight analog. If one or more countermeasures are effective, they will be translated for validation with the suite of operationally implemented in-flight countermeasures.

T R Macaulay↗
NASA NTRS1999

Cortisol, insulin and leptin during space flight and bed rest

Most ground based models for studying muscle atrophy and bone loss show reasonable fidelity to the space flight situation. However there are some differences. Investigation of the reasons for these differences can provide useful information about humans during space flight and aid in the refinement of ground based models. This report discusses three such differences, the relationships between: (i) cortisol and the protein loss, (ii) cortisol and ACTH and (iii) leptin, insulin and food intake.

Flight Experiment↗
NASA NTRS1994

Human cardiovascular response to sympathomimetic agents during head-down bed rest: the effect of dietary sodium

Changes in sympathoadrenal function and cardiovascular deconditioning have long been recognized as a feature of the physiological adaptation to microgravity. The deconditioning process, coupled with altered hydration status, is thought to significantly contribute to orthostatic intolerance upon return to Earth gravity. The cardiovascular response to stimulation by sympathomimetic agents before, during, and after exposure to simulated microgravity was determined in healthy volunteers equilibrated on normal or high sodium diets in order to further the understanding of the deconditioning process.

NASA Discipline Number 18-10↗
NASA NTRS2012

Rest-wavelength Fiducials for the ITER Core Imaging X-ray Spectrometer

Absolute wavelength references are needed to derive the plasma velocities from the Doppler shift of a given line emitted by a moving plasma. We show that such reference standards exist for the strongest x-ray line in neonlike W64+, which has become the line of choice for the ITER (Latin the way) core imaging x-ray spectrometer. Close-by standards are the Hf L3 line and the Ir L2 line, which bracket the W64+ line by 30 eV; other standards are given by the Ir L1 and L2 lines and the Hf L1 and L2 lines, which bracket the W64+ line by 40 and 160 eV, respectively. The reference standards can be produced by an x-ray tube built into the ITER spectrometer. We present spectra of the reference lines obtained with an x-ray microcalorimeter and compare them to spectra of the W64+ line obtained both with an x-ray microcalorimeter and a crystal spectrometer

Rest-wavelength↗
DOE OSTI2020

Open Chemistry, JupyterLab, REST, and quantum chemistry

Quantum chemistry must evolve if it wants to fully leverage the benefits of the internet age, where the worldwide web offers a vast tapestry of tools that enable users to communicate and interact with complex data at the speed and convenience of a button press. The Open Chemistry project has developed an open-source framework that offers an end-to-end solution for producing, sharing, and visualizing quantum chemical data interactively on the web using an array of modern tools and approaches. These tools build on some of the best open-source community projects such as Jupyter for interactive online notebooks, coupled with 3D accelerated visualization, state-of-the-art computational chemistry codes including NWChem and Psi4, and emerging machine learning and data mining tools such as ChemML and ANI. They offer flexible formats to import and export data, along with approaches to compare computational and experimental data.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗
DOE OSTI2026

A catalyst that never rests: Cu/ZnO/Al2O3 under CO2 hydrogenation

For decades, the identity of the active site responsible for carbon dioxide-to-methanol conversion on industrial Cu/ZnO/Al₂O₃ has remained at the center of debate in catalysis. In a recent Nature Catalysis study, Lunkenbein and co-workers use operando transmission electron microscopy to reveal this catalyst in constant motion, cycling between alloyed, oxidized, and encapsulated states as it responds to the competing drives of carbon dioxide activation and hydrogenation.

03 NATURAL GAS↗
DOE OSTI2024

Searching for new physics at μ → e facilities with μ + and π + decays at rest

We investigate the ability of μ → e facilities, Mu2e and COMET, to probe, or discover, new physics with their detector validation datasets. The validation of the detector response may be performed using a dedicated run with μ + , collecting data below the Michel edge, E e ≲ 52 MeV ; an alternative strategy using π + → e + ν e may also be considered. We focus primarily on a search for a monoenergetic e + produced via two-body decays μ + → e + X or π + → e + X , with X a light new physics particle. Mu2e can potentially explore new parameter space beyond present astrophysical and laboratory constraints for a set of well motivated models including axionlike particles with flavor violating couplings ( μ + → e + a ), massive Z ′ bosons ( μ + → Z ′ e + ), and heavy neutral leptons ( π + → e + N ). The projected sensitivities presented herein can be achieved in a matter of days. Published by the American Physical Society 2024

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗
DOE OSTI2023

Electron Transfer Beyond the Outer Membrane: Putting Electrons to Rest

Extracellular electron transfer (EET) is the physiological process that enables the reduction or oxidation of molecules and minerals beyond the surface of a microbial cell. The first bacteria characterized with this capability were Shewanella and Geobacter, both reported to couple their growth to the reduction of iron or manganese oxide minerals located extracellularly. A key difference between EET and nearly every other respiratory activity on Earth is the need to transfer electrons beyond the cell membrane. The past decade has resolved how well-conserved strategies conduct electrons from the inner membrane to the outer surface. However, recent data suggest a much wider and less well understood collection of mechanisms enabling electron transfer to distant acceptors. This review reflects the current state of knowledge from Shewanella and Geobacter, specifically focusing on transfer across the outer membrane and beyond—an activity that enables reduction of highly variable minerals, electrodes, and even other organisms.

59 BASIC BIOLOGICAL SCIENCES↗
DOE OSTI2024

Beam Synchronous for the Rest of Us!

Fermilab’s Tevatron Clock (TCLK) infrastructure has been an integral part of the accelerator control network since the 1980’s. This 10MHz Manchester encoded protocol has enabled flexible, real-time event distribution for thousands of devices connected to the timing network with a high degree of reliability. Forthcoming upgrades to the Fermilab complex (PIP-II, LBNF, ACORN) necessitate higher levels of precision to maintain inter-bunch timing for Instrumentation and Control purposes. This presents as an opportunity to refine the event distribution protocol for tighter synchronization between machines, experiments, and eventually far-site operations. This paper outlines a method by which beam-synchronous events may be distributed through asynchronous serial protocols via integration with local LLRF and global PPS reference signals. This method is ideal for synchrotron machines with aggressive frequency sweeps (such as Fermilab's 38~53MHz Booster) and allows for precision timing to be maintained across machines without specialized hardware.

43 PARTICLE ACCELERATORS↗
DOE OSTI2025

Neutrino Physics Opportunities with Pion and Kaon Decay-at-Rest Neutrino Source

Low-energy neutrino sources, such as those from stopped-pion, stopped-kaon or core-collapse supernova, interact with target nuclei in detectors through either coherent elastic or inelastic scattering processes. These interactions provide valuable insights into various Standard Model and Beyond the Standard Model phenomena, with significant implications for nuclear physics, particle physics, and astrophysics. The precision of coherent elastic scattering, where the nucleus remains in its ground state, depends on the accuracy of the underlying weak form factor of the nucleus. In contrast, inelastic scattering, where neutrinos excite the target nucleus to low-lying nuclear states, involves complex nuclear structures and dynamics and are quite poorly constrained. In this talk, I will present the physics opportunities offered by these neutrino sources, produced as secondary beams in an electron beam dump configuration at Jefferson Lab, and discuss their synergy with global neutrino experiments.

Pandey, Vishvas [Fermilab]↗
DOE OSTI2021

Are Type Ia Supernovae in Rest-frame H Brighter in More Massive Galaxies?

We analyze 143 Type Ia supernovae (SNe Ia) observed in H band (1.6–1.8 μm) and find that SNe Ia are intrinsically brighter in H band with increasing host galaxy stellar mass. We find that SNe Ia in galaxies more massive than 10 10.43 M ⊙ are 0.13 ± 0.04 mag brighter in H than SNe Ia in less massive galaxies. The same set of SNe Ia observed at optical wavelengths, after width–color–luminosity corrections, exhibit a 0.10 ± 0.03 mag offset in the Hubble residuals. We observe an outlier population (|ΔH max | > 0.5 mag) in the H band and show that removing the outlier population moves the mass threshold to 10 10.65 M ⊙ and reduces the step in H band to 0.08 ± 0.04 mag, but the equivalent optical mass step is increased to 0.13 ± 0.04 mag. We conclude that the outliers do not drive the brightness–host-mass correlation. Less massive galaxies preferentially host more higher-stretch SNe Ia, which are intrinsically brighter and bluer. It is only after correction for width–luminosity and color–luminosity relationships that SNe Ia have brighter optical Hubble residuals in more massive galaxies. Thus, finding that SNe Ia are intrinsically brighter in H in more massive galaxies is an opposite correlation to the intrinsic (pre-width–luminosity correction) optical brightness. If dust and the treatment of intrinsic color variation were the main driver of the host galaxy mass correlation, we would not expect a correlation of brighter H-band SNe Ia in more massive galaxies.

79 ASTRONOMY AND ASTROPHYSICS↗
DOE OSTI2022

The Physical Properties of Low-redshift FeLoBAL Quasars. II. The Rest-frame Optical Emission Line Properties

We report the results of an analysis of the Hβ emission line region of a sample of 30 low-redshift (z < 1) iron low-ionization broad absorption line quasars (FeLoBALQs). Eleven of these objects are newly classified as FeLoBALQs. A matched sample of 132 unabsorbed quasars was analyzed in parallel. The emission lines showed the well-known anticorrelation between the [O III ] and Fe II emission. Using a summary statistic called E1 to quantify this anticorrelation, we found that while the distribution of E1 for the unabsorbed quasars has a single peak, the FeLoBALQs have a bimodal shape in this parameter. Previous studies have shown that the line emission properties of BAL and non-BALQs are consistent; therefore, the difference in the Hβ region emission between FeLoBALQs and unabsorbed quasars is a new result. The two populations of FeLoBALQs are characterized by low and high bolometric luminosities and Eddington ratios. Some previous studies have suggested that BALQs are high accretion rate objects and therefore the discovery of the low accretion rate branch of FeLoBAL quasars was unexpected. We also found that the Hβ FWHM is systematically broader among the FeLoBALQs, implying a higher inclination viewing angle or a dearth of low velocity line emitting gas.

79 ASTRONOMY AND ASTROPHYSICS↗