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At least 397 records · Page 22

Microgravity Effects on Transendothelial Transport

The Endothelial Cell (EC) layer which lines blood vessels from the aorta to the capillaries provides the principal barrier to transport of water and solutes between blood and underlying tissue. Endothelial cells are continuously exposed to the mechanical shearing force (shear stress) and normal force (pressure) imposed by flowing blood on their surface, and they are adapted to this mechanical environment. When the cardiovascular system is exposed to microgravity, the mechanical environmental of endothelial cells is perturbed drastically and the transport properties of EC layers are altered in response. We have shown recently that step changes in shear stress have an acute effect on transport properties of EC layers in a cell culture model, and several recent studies in different vessels of live animals have confirmed the shear-dependent transport properties of the endothelium. We hypothesize that alterations in mechanical forces induced by microgravity and their resultant influence on transendothelial transport of water and solutes are, in large measure, responsible for the characteristic cephalad fluid shift observed in humans experiencing microgravity. To study the effects of altered mechanical forces on transendothelial transport and to test pharmacologic agents as counter measures to microgravity induced fluid shifts we have proposed ground-based studies using well defined cell culture models.

Tarbell, John M.↗

The role of the margins in ice stream dynamics

At first glance, it would appear that the bed of the active ice stream plays a much more important role in the overall force balance than do the margins, especially because the ratio of the half-width to depth for a typical ice stream is large (15:1 to 50:1). On the other hand, recent observations indicate that at least part of the ice stream is underlain by a layer of very weak till (shear strength about 2 kPa), and this weak basal layer would then imply that some or all of the resistive drag is transferred to the margins. In order to address this question, a detailed velocity profile near Upstream B Camp, which extends from the center of the ice stream, across the chaotic shear margin, and onto the Unicorn, which is part of the slow-moving ice sheet was measured. Comparison of this observed velocity profile with finite-element models of flow shows several interesting features. First, the shear stress at the margin is on the order of 130 kPa, while the mean value along the bed is about 15 kPa. Integration of these stresses along the boundaries indicates that the margins provide 40 to 50 percent, and the bed, 60 to 40 percent of the total resistive drag needed to balance the gravitational driving stress in this region. (The range of values represents calculations for different values of surface slope.) Second, the mean basal stress predicted by the models shows that the entire bed cannot be blanketed by the weak till observed beneath upstream B - instead there must be a distribution of weak till and 'sticky spots' (e.g., 85 percent till and 15 percent sticky spots of resistive stress equal to 100 kPa). If more of the bed were composed of weak till, then the modeled velocity would not match that observed. Third, the ice must exhibit an increasing enhancement factor as the margins are approached (E equals 10 in the chaotic zone), in keeping with laboratory measurements on ice under prolonged shear strain. Also, there is either a narrow zone of somewhat stiffer ice (E equals 5) outward of the shear margin, or the bed is frozen there. And last, the high shear stress and strain rate found at the margin are likely to cause significant viscous heating (q) in the marginal ice. The increase in temperature is proportional to qX/u, where X is the width of the shear zone and u is the transverse velocity component bringing cold ice in from the ice sheet outside the shear zone. Near upstream B, this heating is likely to cause an increase in temperature of 4 to 10 K. Plans are to measure this temperature increase in a series of bore holes near the margin during the 1992-93 field season, as well as to provide a more detailed description of the velocity field there.

Echelmeyer, Keith↗

Dissipative heating effects and end corrections for viscous Newtonian flow in high shear capillary tube viscometry

The effect of dissipation heating on the apparent viscosity measured in capillary tube viscometry is described in this paper. Conditions of low Reynolds number and high shear are assumed. End corrections to the tube flow are incorporated. The flow curves show decreasing apparent viscosity when the shear stress increases. The configuration of the flow curves plotted in logarithmic presentation are found to be identical for fluids with Newtonian behavior. Convection is the predominant mechanism in removal of the heat in short capillary tube. The estimated upper bound for the shear stress obtainable in short length capillary tubes appears to be of the order of magnitude of 10 MPa limited primarily by the pressure drop associated with the constant end correction from the flat ended inlet and exit of the tube.

Jakobsen, J.↗

A comparison of turbulence closure models for transonic flows about airfoils

Navier-Stokes transonic airfoil calculations using three different turbulence closure models are presented and compared with available experimental data. Two of the models, Cebeci-Smith and Baldwin-Lomax, are equilibrium models in the sense that the turbulent shear stress is assumed to depend only on the local properties of the mean flow. The third model, Johnson and King, is a nonequilibrium model in which an ordinary differential equation is employed to account for the streamwise development of the maximum Reynolds shear stress. An eddy viscosity distribution across the boundary layer is assumed which is functionally dependent on this stress. For attached flows with little inviscid-viscous interaction, little difference in the results with the different models is noted. With stronger interactions and with separation occurring on the airfoils, the nonequilibrium model is shown to perform better.

King, Lyndell S.↗

Turbulent boundary layer on a convex, curved surface

The effects of strong convex curvature on boundary layer turbulence were investigated. The data gathered on the behavior of Reynolds stress suggested the formulation of a simple turbulence model. Three sets of data were taken on two separate facilities. Both rigs had flow from a flat surface, over a convex surface with 90 deg of turning, and then onto a flat recovery surface. The geometry was adjusted so that, for both rigs, the pressure gradient along the test surface was zero - thus avoiding any effects of streamwise acceleration on the wall layers. Results show that after a sudden introduction of curvature, the shear stress in the outer part of the boundary layer is sharply diminished and is even slightly negative near the edge. The wall shear also drops off quickly downstream. In contrast, when the surface suddenly becomes flat again, the wall shear and shear stress profiles recover very slowly towards flat wall conditions.

Gillis, J. C.↗

Experimental data and model for the turbulent boundary layer on a convex, curved surface

Experiments were performed to determine how boundary layer turbulence is affected by strong convex curvature. The data gathered on the behavior of the Reynolds stress suggested the formulation of a simple turbulence model. Data were taken on two separate facilities. Both rigs had flow from a flat surface, over a convex surface with 90 deg of turning and then onto a flat recovery surface. The geometry was adjusted so that, for both rigs, the pressure gradient along the test surface was zero. Two experiments were performed at delta/R approximately 0.10, and one at weaker curvature with delta/R approximately 0.05. Results show that after a sudden introduction of curvature the shear stress in the outer part of the boundary layer is sharply diminished and is even slightly negative near the edge. The wall shear also drops off quickly downstream. When the surface suddenly becomes flat again, the wall shear and shear stress profiles recover very slowly towards flat wall conditions. A simple turbulence model, which was based on the theory that the Prandtl mixing length in the outer layer should scale on the velocity gradient layer, was shown to account for the slow recovery.

Gillis, J. C.↗

Local and overall aerodynamic coefficients for bodies in hypersonic, rarefied flow

A computational method is given for the prediction of local pressure and viscous shear stress on windward surfaces of bluff, convex, axisymmetric or quasi-axisymmetric, hypersonic bodies in the transitional, rarefied flow regime. Overall aerodynamic forces and moments are computed by integration of the local quantities. The method is based upon a correlation of local pressure and shear stress computed by the direct simulation Monte Carlo (DSMC) numerical technique for cold wall, real gas conditions and some supplemental data from low-density, hypersonic wind tunnels. The relative simplicity of the method makes it feasible to do the necessary calculations with a personal computer. Two-dimensional shapes and leeward surfaces are not included in the scope of the method as it is presented here. Results are compared with DSMC computations for both local and overall coefficients. The latter includes sphere and blunt cone drag as well as lift and pitching moment coefficients for the NASA AFE vehicle at various angles of attack. Very satisfactory agreement is shown.

Potter, J. Leith↗

Skin-Friction Measurements in Incompressible Flow

Experiments have been conducted to measure the local surface-shear stress and the average skin-friction coefficient in Incompressible flow for a turbulent boundary layer on a smooth flat plate having zero pressure gradient. Data were obtained for a range of Reynolds numbers from 1 million to 45 million. The local surface-shear stress was measured by a floating-element skin-friction balance and also by a calibrated total head tube located on the surface of the test wall. The average skin-friction coefficient was obtained from boundary-layer velocity profiles.

Smith, Donald W.↗

Rough-to-smooth transition of an equilibrium neutral constant stress layer

Purpose of research on rough-to-smooth transition of an equilibrium neutral constant stress layer is to develop a model for low-level atmospheric flow over terrains of abruptly changing roughness, such as those occurring near the windward end of a landing strip, and to use the model to derive functions which define the extent of the region affected by the roughness change and allow adequate prediction of wind and shear stress profiles at all points within the region. A model consisting of two bounding logarithmic layers and an intermediate velocity defect layer is assumed, and dimensionless velocity and stress distribution functions which meet all boundary and matching conditions are hypothesized. The functions are used in an asymptotic form of the equation of motion to derive a relation which governs the growth of the internal boundary layer. The growth relation is used to predict variation of surface shear stress.

Logan, E., Jr.↗

Preston tube calibrations and direct force floating element measurements in a two-dimensional turbulent boundary layer

Preston tubes provide a convenient means of estimating local wall shear stress. Practical difficulties arise from a lack of calibration data obtained in turbulent boundary layer flows and from the wide choice of calibration equations available mainly from pipe flow calibrations. The results of an experimental study comparing a large number of direct force local wall shear stress measurements in a near-zero pressure gradient two-dimensional turbulent boundary layer flow are presented. The results indicate that there is consistent and excellent agreement between the Patel intermediate calibration formula and the direct force measurements. Typical differences among the direct force measurements and several other proposed calibration equations are also shown.

Mcallister, J. E.↗

Vortex-induced disturbance field in a compressible shear layer

The disturbance field induced by a small isolated vortex in a compressible shear layer is studied using direct simulation in a convected frame. The convective Mach number, M(sub c), is varied from 0.1 to 1.25. The vorticity perturbation is rapidly sheared by the mean velocity gradient. The resulting disturbance pressure field is observed to decrease both in magnitude and extent with increasing M(sub c), becoming a narrow transverse zone for M(sub c) greater than 0.8. A similar trend is seen for the perturbation velocity magnitude and for the Reynolds shear stress. By varying the vortex size, we verified that the decrease in perturbation levels is due to the mean-flow Mach number and not the Mach number across the vortex. At high M(sub c), the vortex still communicates with the edges of the shear layer, although communication in the mean-flow direction is strongly inhibited. The growth rate of perturbation kinetic energy declines with M(sub c) primarily due to the reduction in shear stress. For M(sub c) greater than or equal to 0.6, the pressure dilatation also contributes to the decrease of growth rates. Calculation of the perturbation field induced by a vortex doublet revealed the same trends as in the single-vortex case, illustrating the insensitivity of the Mach-number effect to the specific form of initial conditions.

Papamoschou, D.↗

Simulation of cryogenic turbopump annular seals

San Andres employed the NBS software package MIPROPS to account for density's dependence on pressure in the simulation of liquid annular seals. His example on a LH2 seal showed a significant change in the mass coefficient compared to a constant density model. San Andres, Yang, and Childs extended this analysis by including the pressure and temperature dependence of density, specific heat, viscosity, volumetric expansion, and thermal conductivity in a coupled solution of the energy, momentum, and continuity equations. Their example showed very significant changes in stiffness and inertia for a high speed (38,000 rpm), large L/D ratio (0.5) LOX seal, as compared to their constant temperature results. The current research rederived the San Andres-Yang-Childs (SYC) analysis and extended it to include not only the Moody friction model of SYC but also the Hir's friction model. The derivation begins with obtaining the local differential equations of continuity, momentum, and energy conservation in the seal. These equations are averaged across the film thickness to obtain the resulting 'bulk flow' differential equations. Shear stress and convective heat loss through the stator (seal) and rotor are related to the Moody and Hir's friction factor model. The Holman analogy is employed to relate heat conduction in or out of the fluid film's boundary layer to the friction induced shear stress.

Palazzolo, Alan B.↗

A photoelastic investigation of asymmetric four point bend shear test for composite materials

The shear stress fringe value of orthotropic birefringent model materials is presently used in an asymmetric four-point bend test that employs a notched specimen and is a modification of the Iosipescu test (1967). While in the case of a unidirectionally reinforced glass-polyester model material, shear stress fringe values obtained from 90- and 120-deg (sharp and radiused) notches are reasonably close to the values obtained for an off-axis tensile specimen, no conclusions can be drawn on the influence of the notch parameters, due to the peculiarities of the photoelastic response of the inhomogeneous orthotropic model material. The failure modes nevertheless indicate that a notch radius, and the 120-deg notch angle, reduce the stress concentration. Comparisons are made with finite element results.

Prabhakaran, R.↗

Variation in Velocity Profile with Change in Surface Roughness of Boundary

The present report deals with the variation of a turbulent velocity profile in flow from rough to smooth wall and vice versa. Expressions obtained for the shear-stress distribution with respect to the distance from the point of junction of the different roughnesses and from the wall distance, are utilized to ascertain the developing velocity distributions. Under simplified assumptions, the use of these formulas renders possible the integration of the motion equations for the shear stress. This calculation is carried out and compared with the experiments.

Jacobs, W↗

Linear Reciprocating Tribometer for In Situ Neutron Reflectometry of Soft Matter

Neutron reflectometry is a technique for measuring structure near planar interfaces that has been previously used to non-destructively characterize the polymer density of hydrated, dilute, and soft materials. Previous investigations have conducted neutron reflectometry measurements of liquids, gels, emulsion, and polymer solutions at rest, in compression, and subject to shear stress. However, correlating structure with tribological properties of soft materials presents significant experimental challenges for prior instruments due to wall slip, sample thickness, and structural heterogeneity (e.g., depth-wise gradients). A linear reciprocating tribometer offers several advantages for in situ neutron reflectometry studies, including uniform velocity profiles, constant shear stress over large regions of interest, and independent control of normal force and sliding velocity during measurements. This work outlines basic considerations for the design of a custom linear reciprocating tribometer that operates in a neutron beamline and includes commissioning measurements. The tribometer is designed to compress soft and hydrated materials against linearly reciprocating silicon disks. The three key design considerations for this tribometer are (1) safety, (2) neutron transmission, and (3) sample positioning. This instrument design will enable in situ studies of soft matter and illuminate the role of interfacial structure on tribological phenomena.

42 ENGINEERING↗

Applicability of Mixing Length Theory to a Turbulent Vortex System

The ability of mixing length theory to correlate vortex data is evaluated. Expressions are derived for eddy diffusivity by applying the techniques of von Karman and Prandtl which have been established for pipe flow. Total and static pressures were measured from the outer radius to the exhaust-nozzle radius of a vortex generator for a range of mass flows. These data are combined with Navier-Stokes solutions for this region of a compressible vortex to determine turbulent Reynolds numbers. The Reynolds number is related to Prandtl and Karman functions for various assumed boundary conditions, and the experimental data are used to determine the usefulness of these expressions. The following conclusions were reached: (1) Mixing length functions developed by applying von Karman's similarity hypothesis to vortex motion correlate the data better than do Prandtl functions obtained with the assumption that mixing length is proportional to radius. (2) Some of the expressions developed do not adequately represent the experimental data. (3) The data are correlated with acceptable scatter by evaluating the fluid radial inertia at the outer boundary and the shear stress at the inner boundary. The universal constant K was found to be 0.04 to 0.08, rather than the value of 0.4 which is accepted for rectilinear flow. (4) The data are best correlated by a modified Karman expression which includes an effect of radial inertia, as well as shear stress, on eddy diffusivity.

Ragsdale, Robert G.↗

Alkaline phosphatase in osteoblasts is down-regulated by pulsatile fluid flow

It is our hypothesis that interstitial fluid flow plays a role in the bone remodeling response to mechanical loading. The fluid flow-induced expression of three proteins (collagen, osteopontin, and alkaline phosphatase) involved in bone remodeling was investigated. Rat calvarial osteoblasts subjected to pulsatile fluid flow at an average shear stress of 5 dyne/cm2 showed decreased alkaline phosphatase (AP) mRNA expression after only 1 hour of flow. After 3 hours of flow, AP mRNA levels had decreased to 30% of stationary control levels and remained at this level for an additional 5 hours of flow. Steady flow (4 dyne/cm2 fluid shear stress), in contrast, resulted in a delayed and less dramatic decrease in AP mRNA expression to 63% of control levels after 8 hours of flow. The reduced AP mRNA expression under pulsatile flow conditions was followed by reduced AP enzyme activity after 24 hours. No changes in collagen or osteopontin mRNA expression were detected over 8 hours of pulsatile flow. This is the first time fluid flow has been shown to affect gene expression in osteoblasts.

Non-NASA Center↗

Aerothermodynamic Environments Definition for the Mars Science Laboratory Entry Capsule

An overview of the aerothermodynamic environments definition status is presented for the Mars Science Laboratory entry vehicle. The environments are based on Navier-Stokes flowfield simulations on a candidate aeroshell geometry and worst-case entry heating trajectories. Uncertainties for the flowfield predictions are based primarily on available ground data since Mars flight data are scarce. The forebody aerothermodynamics analysis focuses on boundary layer transition and turbulent heating augmentation. Turbulent transition is expected prior to peak heating, a first for Mars entry, resulting in augmented heat flux and shear stress at the same heatshield location. Afterbody computations are also shown with and without interference effects of reaction control system thruster plumes. Including uncertainties, analysis predicts that the heatshield may experience peaks of 225 W/sq cm for turbulent heat flux, 0.32 atm for stagnation pressure, and 400 Pa for turbulent shear stress. The afterbody heat flux without thruster plume interference is predicted to be 7 W/sq cm on the backshell and 10 W/sq cm on the parachute cover. If the reaction control jets are fired near peak dynamic pressure, the heat flux at localized areas could reach as high as 76 W/sq cm on the backshell and 38 W/sq cm on the parachute cover, including uncertainties. The final flight environments used for hardware design will be updated for any changes in the aeroshell configuration, heating design trajectories, or uncertainties.

Edquist, Karl T.↗