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At least 397 records · Page 22

An Arbitrary Time Interval Generator Base on Vernier Clocks with 0.67 ps Adjustable Steps Implemented in FPGA

In TDC testing and timing system implementations, it is often necessary to generate signal pulses with finely adjustable time intervals. In delay cell–based schemes, the adjustment resolution is constrained by the propagation delay of the cells—typically 15–20 ps per step—and is sensitive to temperature and supply voltage variations. This document presents a fully digital approach that uses two vernier clocks, generated by two stages of cascaded phase-locked loops (PLLs) with a slight frequency difference, to achieve adjustable timing intervals through accumulated phase differences. The scheme was validated on two families of low-cost FPGA devices, achieving adjustable step sizes of 0.67 ps and 0.97 ps.

Wu, Jin-yuan [Fermilab] (ORCID:0000000344329521)↗

Reference Mission Version 3.0 Addendum to the Human Exploration of Mars: The Reference Mission of the NASA Mars Exploration Study Team

This Addendum to the Mars Reference Mission was developed as a companion document to NASA Special Publication 6107, “Human Exploration of Mars: The Reference Mission of the NASA Exploration Study Team.” The Addendum summarizes changes and updates to the Mars Reference Mission the Exploration Office developed since the final draft of SP 6107 was printed in early 1998. The Reference Mission is a tool used by the Exploration Team and the exploration community to compare and evaluate approaches to mission and system concepts that could be used for human exploration missions. It is intended to identify and clarify system “drivers,” or significant sources of cost, performance, risk, and schedule variation. It does not represent a final or recommended approach to human Mars missions. Several alternative scenarios, including human exploration missions to the Moon, asteroids, or other targets beyond Earth orbit as well as employing different technical approaches to solving mission and technology challenges, are currently under study by the Exploration Team. Comparing alternative approaches provides the basis for continual improvement to technology investment plans and general understanding of future human exploration missions. The Addendum represents a “snapshot” of work in progress in support of planning for future human exploration missions through May 1998. Annual publications of revisions to the Reference Mission are planned beginning in late 1998.

Mars↗

Transcripts and genomic intervals associated with variation in metabolite abundance in maize leaves under field conditions

Abstract Plants exhibit extensive environment-dependent intraspecific metabolic variation, which likely plays a role in determining variation in whole plant phenotypes. However, much of the work seeking to use natural variation to link genes and transcript’s impacts on plant metabolism has employed data from controlled environments. Here, we generated and analyzed data on the variation in the abundance of 26 metabolites across 660 maize inbred lines under field conditions. We employ these data and previously published transcript and whole plant phenotype data reported for the same field experiment to identify both genomic intervals (through genome-wide association studies (GWAS)) and transcripts (using both transcriptome-wide association studies (TWAS) and an explainable artificial intelligence (AI) approach based on random forest (RF)) associated with variation in metabolite abundance. Both genome-wide association and random forest-based methods identified substantial numbers of significant associations including genes with plausible links to the metabolites they are associated with. In contrast, the transcriptome-wide association identified only six significant associations. In three cases, genetic markers associated with metabolic variation in our study colocalized with markers linked to variation in non-metabolic traits scored in the same experiment. We speculate that the poor performance of transcriptome-wide association studies in identifying transcript-metabolite associations may reflect a high prevalence of non-linear interactions between transcripts and metabolites and/or a bias towards rare transcripts playing a large role in determining intraspecific metabolic variation.

Mathivanan, Ramesh Kanna↗

Full event particle-level unfolding with variable-length latent variational diffusion

The measurements performed by particle physics experiments must account for the imperfect response of the detectors used to observe the interactions. One approach, unfolding, statistically adjusts the experimental data for detector effects. Recently, generative machine learning models have shown promise for performing unbinned unfolding in a high number of dimensions. However, all current generative approaches are limited to unfolding a fixed set of observables, making them unable to perform full-event unfolding in the variable dimensional environment of collider data. A novel modification to the variational latent diffusion model (VLD) approach to generative unfolding is presented, which allows for unfolding of high- and variable-dimensional feature spaces. The performance of this method is evaluated in the context of semi-leptonic t\bar{t} t t ‾ production at the Large Hadron Collider.

Shmakov, Alexander↗

A Game-Theoretic Quantum Algorithm for Solving Magic Squares

Variational quantum algorithms (VQAs) offer a promising near-term approach to finding optimal quantum strategies for playing non-local games. These games test quantum correlations beyond classical limits and enable entanglement verification. In this work, we present a variational framework for the Magic Square Game (MSG), a two-player non-local game with perfect quantum advantage. We construct a value Hamiltonian that encodes the game’s parity and consistency constraints, then optimize parameterize quantum circuits to minimize this cost. Our approach build on the stabilizer formalism, leverages commutation structure for circuit design, and is hardware-efficient. Compared to existing work, our contribution emphasizes algebraic structure an interpretability. We validate our method through numerical experiments and outline generalizations to larger games.

Chehade, Sarah [ORNL]↗

From minerals to rocks: Toward modeling lithologies with remote sensing

High spectral resolution imaging spectroscopy will play an important role in future planetary missions. Sophisticated approaches will be needed to unravel subtle, super-imposed spectral features typically of natural systems, and to maximize the science return of these instruments. Carefully controlled laboratory investigations using homogeneous mineral separates have demonstrated that variations due to solid solution, changes in modal abundances, and the effects of particle size are well understood from a physical basis. In many cases, these variations can be modeled quantitatively using photometric models, mixing approaches, and deconvolution procedures. However, relative to the spectra of individual mineral components, reflectance spectra of rocks and natural surfaces exhibit a reduced spectral contrast. In addition, soils or regolith, which are likely to dominate any natural planetary surface, exhibit spectral properties that have some similarities to the parent materials, but due to weathering and alteration, differences remain that cannot yet be fully recreated in the laboratory or through mixture modeling. A significant challenge is therefore to integrate modeling approaches to derive both lithologic determinations and include the effects of alteration. We are currently conducting laboratory investigations in lithologic modeling to expand upon the basic results of previous analyses with our initial goal to more closely match physical state of natural systems. The effects of alteration are to be considered separately.

Mustard, John F.↗

Neptune's cloud structure in 1989 - Photometric variations and correlation with ground-based images

Ground-based photoelectric photometry in b, y, and the 6190 and 7250 A methane-bands, as well as spectrum scans of the methane 6190 A band and CCD images at 6190 and 8900 A, were obtained for Neptune during Voyager 2's approach of that planet on August 24, 1989. Photometric variations are presently correlated with the disk transit of bright planetary features, and the changes in feature distribution and brightness noted in the results are evaluated for implications bearing on long-term variability. It is suggested that the long-term secular variation is related to a slow change in a size of location of both the bright companion and the Great Dark Spot.

Lockwood, G. W.↗

Assessment of Low Cycle Fatigue Behavior of Powder Metallurgy Alloy U720

The fatigue lives of modem powder metallurgy disk alloys are influenced by variabilities in alloy microstructure and mechanical properties. These properties can vary as functions of variables the different steps of materials/component processing: powder atomization, consolidation, extrusion, forging, heat treating, and machining. It is important to understand the relationship between the statistical variations in life and these variables, as well as the change in life distribution due to changes in fatigue loading conditions. The objective of this study was to investigate these relationships in a nickel-base disk superalloy, U720, produced using powder metallurgy processing. Multiple strain-controlled fatigue tests were performed at 538 C (1000 F) at limited sets of test conditions. Analyses were performed to: (1) assess variations of microstructure, mechanical properties, and LCF failure initiation sites as functions of disk processing and loading conditions; and (2) compare mean and minimum fatigue life predictions using different approaches for modeling the data from assorted test conditions. Significant variations in life were observed as functions of the disk processing variables evaluated. However, the lives of all specimens could still be combined and modeled together. The failure initiation sites for tests performed at a strain ratio R(sub epsilon) = epsilon(sub min)/epsilon(sub max) of 0 were different from those in tests at a strain ratio of -1. An approach could still be applied to account for the differences in mean and maximum stresses and strains. This allowed the data in tests of various conditions to be combined for more robust statistical estimates of mean and minimum lives.

Gabb, Tomothy P.↗

SABER (TIMED) and MLS (UARS) Temperature Observations of Mesospheric and Stratospheric QBO and Related Tidal Variations

More than three years of temperature observations from the SABER (TIMED) and MLS WARS) instruments are analyzed to study the annual and inter-annual variations extending from the stratosphere into the upper mesosphere. The SABER measurements provide data from a wide altitude range (15 to 95 km) for the years 2002 to 2004, while the MLS data were taken in the 16 to 55 km altitude range a decade earlier. Because of the sampling properties of SABER and MLS, the variations with local solar time must be accounted for when estimating the zonal mean variations. An algorithm is thus applied that delineates with Fourier analysis the year-long variations of the migrating tides and zonal mean component. The amplitude of the diurnal tide near the equator shows a strong semiannual periodicity with maxima near equinox, which vary from year to year to indicate the influence from the Quasi-biennial Oscillation (QBO) in the zonal circulation. The zonal mean QBO temperature variations are analyzed over a range of latitudes and altitudes, and the results are presented for latitudes from 48"s to 48"N. New results are obtained for the QBO, especially in the upper stratosphere and mesosphere, and at mid-latitudes. At Equatorial latitudes, the QBO amplitudes show local peaks, albeit small, that occur at different altitudes. From about 20 to 40 km, and within about 15" of the Equator, the amplitudes can approach 3S K for the stratospheric QBO or SQBO. For the mesospheric QBO or MQBO, we find peaks near 70 km, with temperature amplitudes reaching 3.5"K, and near 85 km, the amplitudes approach 2.5OK. Morphologically, the amplitude and phase variations derived from the SABER and MLS measurements are in qualitative agreement. The QBO amplitudes tend to peak at the Equator but then increase again pole-ward of about 15" to 20'. The phase progression with altitude varies more gradually at the Equator than at mid-latitudes. A comparison of the observations with results from the Numerical Spectral Model (NSM) reveals that there is qualitative agreement. The NSM generates the QBO extending from the stratosphere into the upper mesosphere, with temperature variations extending to mid latitudes, but the predicted amplitudes are smaller than those observed.

Huang, Frank T.↗

Spectral Ratio Imaging with Hyperion Satellite Data for Geological Mapping

Since the advent of LANDSAT I in 1972, many different multispectral satellites have been orbited by the U.S. and other countries. These satellites have varied from 4 spectral bands in LANDSAT I to 14 spectral bands in the ASTER sensor aboard the TERRA space platform. Hyperion is a relatively new hyperspectral sensor with over 220 spectral bands. The huge increase in the number of spectral bands offers a substantial challenge to computers and analysts alike when it comes to the task of mapping features on the basis of chemical composition, especially if little or no ground truth is available beforehand from the area being mapped. One approach is the theoretical approach of the modeler, where all extraneous information (atmospheric attenuation, sensor electronic gain and offset, etc.) is subtracted off and divided out, and laboratory (or field) spectra of materials are used as training sets to map features in the scene of similar composition. This approach is very difficult to keep accurate because of variations in the atmosphere, solar illumination, and sensor electronic gain and offset that are not always perfectly recorded or accounted for. For instance, to apply laboratory or field spectra of materials as data sets from the theoretical approach, the header information of the files must reflect the correct, up-to-date sensor electronic gain and offset and the analyst must pick the exact atmospheric model that is appropriate for the day of data collection in order for classification procedures to accurately match pixels in the scene with the laboratory or field spectrum of a desired target on the basis of the hyperspectral data. The modeling process is so complex that it is difficult to tell when it is operating well or determine how to fix it when it is incorrect. Recently RSI has announced that the latest version of their ENVI software package is not performing atmospheric corrections correctly with the FLAASH atmospheric model. It took a long time to determine that it was wrong, and may take an equally long time (or longer) to fix.

Vincent, Robert K.↗

Document analysis with neural net circuits

Document analysis is one of the main applications of machine vision today and offers great opportunities for neural net circuits. Despite more and more data processing with computers, the number of paper documents is still increasing rapidly. A fast translation of data from paper into electronic format is needed almost everywhere, and when done manually, this is a time consuming process. Markets range from small scanners for personal use to high-volume document analysis systems, such as address readers for the postal service or check processing systems for banks. A major concern with present systems is the accuracy of the automatic interpretation. Today's algorithms fail miserably when noise is present, when print quality is poor, or when the layout is complex. A common approach to circumvent these problems is to restrict the variations of the documents handled by a system. In our laboratory, we had the best luck with circuits implementing basic functions, such as convolutions, that can be used in many different algorithms. To illustrate the flexibility of this approach, three applications of the NET32K circuit are described in this short viewgraph presentation: locating address blocks, cleaning document images by removing noise, and locating areas of interest in personal checks to improve image compression. Several of the ideas realized in this circuit that were inspired by neural nets, such as analog computation with a low resolution, resulted in a chip that is well suited for real-world document analysis applications and that compares favorably with alternative, 'conventional' circuits.

Graf, Hans Peter↗

Novel Estimation of Pilot Performance Characteristics

Two mechanisms internal to the pilot that affect performance during a tracking task are: 1) Pilot equalization (i.e. lead/lag); and 2) Pilot gain (i.e. sensitivity to the error signal). For some applications McRuer's Crossover Model can be used to anticipate what equalization will be employed to control a vehicle's dynamics. McRuer also established approximate time delays associated with different types of equalization - the more cognitive processing that is required due to equalization difficulty, the larger the time delay. However, the Crossover Model does not predict what the pilot gain will be. A nonlinear pilot control technique, observed and coined by the authors as 'amplitude clipping', is shown to improve stability, performance, and reduce workload when employed with vehicle dynamics that require high lead compensation by the pilot. Combining linear and nonlinear methods a novel approach is used to measure the pilot control parameters when amplitude clipping is present, allowing precise measurement in real time of key pilot control parameters. Based on the results of an experiment which was designed to probe workload primary drivers, a method is developed that estimates pilot spare capacity from readily observable measures and is tested for generality using multi-axis flight data. This paper documents the initial steps to developing a novel, simple objective metric for assessing pilot workload and its variation over time across a wide variety of tasks. Additionally, it offers a tangible, easily implementable methodology for anticipating a pilot's operating parameters and workload, and an effective design tool. The model shows promise in being able to precisely predict the actual pilot settings and workload, and observed tolerance of pilot parameter variation over the course of operation. Finally, an approach is proposed for generating Cooper-Harper ratings based on the workload and parameter estimation methodology.

Human pilot models↗

Kinematic Modeling of Separation Compression for Paired Approaches to Closely-Spaced Parallel Runways

In a simultaneous paired approach to closely-spaced parallel runways, a pair of aircraft flies in close proximity on parallel approach paths. The longitudinal separation between the aircraft must be maintained within a range that avoids wake encounters and, if one of the aircraft blunders, avoids collision. To increase operational availability, the approach procedure must accommodate a mixture of aircraft sizes and, consequently, approach speeds. In these procedures, the slower aircraft is placed in the lead position. The faster aircraft maintains separation from the slow aircraft in a dependent operation until final approach and flies independently afterward. Due to the higher approach speed of the fast aircraft, longitudinal separation will decrease during final approach. Therefore, the fast aircraft must position itself before the final approach so that it will remain within the safe range of separation as separation decreases. Given the approach geometry and speed schedule for each aircraft, one can use kinematics to estimate the separation loss between a pair of aircraft. A kinematic model can complement fast-time Monte-Carlo simulations of the approach by enabling a tailored reduction in the variation of starting position for the fast aircraft. One could also implement the kinematic model in ground-based or on-board decision support tools to compute the optimal initial separation for a given pair of aircraft. To better match the auto-coupled flight of real aircraft, the paper derives a kinematic model where the speed schedule is flown using equivalent airspeed. The predicted time of flight using the equivalent airspeed kinematic model compares well against a high-fidelity aircraft simulation performing the same approach. This model also demonstrates a modest increase in the predicted loss of separation when contrasted against a kinematic model that assumes the scheduled speed is true airspeed.

Madden, Michael M.↗

3D probabilistic fracture mechanics / computational fluid dynamics simulation of a reactor pressure vessel under transient conditions

Reactor pressure vessels (RPVs) are safety-critical light-water-reactor components that, under irradiation, experience long-term material degradation in the form of embrittlement. This can increase their susceptibility to fracture under thermal-shock conditions, which could occur during off-normal transients such as loss-of-coolant accidents (LOCAs). During a LOCA, the most severe conditions for the RPV occur when emergency core cooling water is injected through the cold legs into the water-and-steam-filled RPV. The rapid cooling of the downcomer and internal RPV surface causes decreased temperature and elevated thermally driven tensile stresses in the RPV wall. This, combined with long-term material embrittlement, may cause fracture initiation at pre-existing flaws, challenging the integrity of the RPV. Assessing RPV integrity during transients with a large spatial variation in the coolant temperature requires a modeling approach that considers the effects of spatially varying coolant temperature on the fracture probability of a population of flaws distributed throughout the RPV, accounting for spatially varying embrittlement. Here, the present study addresses this need by demonstrating first-of-its-kind coupling of a high-fidelity 3D computational fluid dynamics code with 3D probabilistic fracture mechanics This was accomplished using representative models of a pressurized-water reactor subjected to small- and medium-break LOCA conditions, both of which can result in large spatial temperature variations. While the observed impact of accounting for 3D effects was minimal under the small-break LOCA this study indicates a significant increase in the probability of fracture initiation under the medium-break LOCA when 3D effects are considered, relative to a spatially uniform cooling scenario.

22 - GENERAL STUDIES OF NUCLEAR REACTORS↗

Learning genetic perturbation effects with variational causal inference

Advances in sequencing technologies have enhanced the understanding of gene regulation in cells. In particular, Perturb-seq has enabled high-resolution profiling of the transcriptomic response to genetic perturbations at the single-cell level. This understanding has implications in functional genomics and potentially for identifying therapeutic targets. Various computational models have been developed to predict perturbational effects. While deep learning models excel at interpolating observed perturbational data, they tend to overfit in the lack of enough data and may not generalize well to unseen perturbations. In contrast, mechanistic models, such as linear causal models based on gene regulatory networks, hold greater potential for extrapolation, as they encapsulate regulatory information that can predict responses to unseen perturbations. However, their application has been limited to small studies due to overly simplistic assumptions, making them less effective in handling noisy, large-scale single-cell data. We propose a hybrid approach that combines a mechanistic causal model with variational deep learning, termed Single Cell Causal Variational Autoencoder (SCCVAE). The mechanistic model employs a learned regulatory network to represent perturbational changes as shift interventions that propagate through the learned network. SCCVAE integrates this mechanistic causal model into a variational autoencoder, generating rich, comprehensive transcriptomic responses. Our results indicate that SCCVAE exhibits superior performance over current state-of-the-art baselines for extrapolating to predict unseen perturbational responses. Additionally, for the observed perturbations, the latent space learned by SCCVAE allows for the identification of functional perturbation modules and simulation of single-gene knockdown experiments of varying penetrance, presenting a robust tool for interpreting and interpolating perturbational responses at the single-cell level.

59 BASIC BIOLOGICAL SCIENCES↗

Efficient Gradient-Based Shape Optimization Methodology Using Inviscid/Viscous CFD

The formerly developed preconditioned-biconjugate-gradient (PBCG) solvers for the analysis and the sensitivity equations had resulted in very large error reductions per iteration; quadratic convergence was achieved whenever the solution entered the domain of attraction to the root. Its memory requirement was also lower as compared to a direct inversion solver. However, this memory requirement was high enough to preclude the realistic, high grid-density design of a practical 3D geometry. This limitation served as the impetus to the first-year activity (March 9, 1995 to March 8, 1996). Therefore, the major activity for this period was the development of the low-memory methodology for the discrete-sensitivity-based shape optimization. This was accomplished by solving all the resulting sets of equations using an alternating-direction-implicit (ADI) approach. The results indicated that shape optimization problems which required large numbers of grid points could be resolved with a gradient-based approach. Therefore, to better utilize the computational resources, it was recommended that a number of coarse grid cases, using the PBCG method, should initially be conducted to better define the optimization problem and the design space, and obtain an improved initial shape. Subsequently, a fine grid shape optimization, which necessitates using the ADI method, should be conducted to accurately obtain the final optimized shape. The other activity during this period was the interaction with the members of the Aerodynamic and Aeroacoustic Methods Branch of Langley Research Center during one stage of their investigation to develop an adjoint-variable sensitivity method using the viscous flow equations. This method had algorithmic similarities to the variational sensitivity methods and the control-theory approach. However, unlike the prior studies, it was considered for the three-dimensional, viscous flow equations. The major accomplishment in the second period of this project (March 9, 1996 to March 8, 1997) was the extension of the shape optimization methodology for the Thin-Layer Navier-Stokes equations. Both the Euler-based and the TLNS-based analyses compared with the analyses obtained using the CFL3D code. The sensitivities, again from both levels of the flow equations, also compared very well with the finite-differenced sensitivities. A fairly large set of shape optimization cases were conducted to study a number of issues previously not well understood. The testbed for these cases was the shaping of an arrow wing in Mach 2.4 flow. All the final shapes, obtained either from a coarse-grid-based or a fine-grid-based optimization, using either a Euler-based or a TLNS-based analysis, were all re-analyzed using a fine-grid, TLNS solution for their function evaluations. This allowed for a more fair comparison of their relative merits. From the aerodynamic performance standpoint, the fine-grid TLNS-based optimization produced the best shape, and the fine-grid Euler-based optimization produced the lowest cruise efficiency.

Baysal, Oktay↗

Investigation of oscillations above the acoustic cut-off frequency for a sample of Kepler stars. II. Identifying temporal frequency shifts

ABSTRACT Stellar oscillations with frequencies greater than the acoustic cut-off frequency are not trapped within the star’s interior. Geometric interference between these high-frequency waves produces a peak-like structure in the power spectrum of the star, known as the pseudo-modes. In this study, we aim to analyse 51 stars previously identified (from a sample of 91 Kepler stars) to contain statistically significant evidence for pseudo-modes, to determine if the pseudo-mode frequencies vary in time. We obtained these frequency variations and the uncertainty by the resampled periodogram approach, where periodogram realisations were created from successive, overlapping 90-d time segments, and a cross-correlation function was generated between them. The computed shifts were compared against temporal p-mode frequency shifts and a stellar magnetic activity proxy, $S_{\mathrm{ph}}$. We found that for 16 per cent of the stars pseudo-mode frequency shifts were significantly anticorrelated with p-mode shifts, as is the case for the Sun. However, we also found pseudo-mode and p-mode shifts to be significantly correlated in-phase in 8 per cent of our sample. The remainder showed no significant correlation. We also searched for trends between the maximum variation of pseudo-mode frequency shifts and stellar parameters. Whilst we found no correlation between the maximum variation and stellar photospheric and chromospheric proxies, we found frequency variations to have a greater amplitude for cooler and slower rotating stars, which is in opposition to p-mode frequency shift variation. Temporal changes to pseudo-mode frequencies may be attributable to variations in stellar magnetic activity, and therefore can contribute to our understanding of stellar activity cycles.

Millson, L. J. (ORCID:0009000342542676)↗

An explainable variational autoencoder model for three-dimensional acoustic emission source localization in hollow cylindrical structures

We introduce an explainable variational autoencoder for three-dimensional (3D) localization of acoustic emission sources in hollow cylindrical structures, with an unsupervised approach. This research capitalizes on multi-arrival waveforms generated by helical path propagation in cylindrical geometries to enable efficient two-receiver localization. By integrating the modal characteristics of Lamb modes under multi-path conditions, we demonstrate that two sets of time-of-arrival differences and peak amplitudes extracted from one receiver can serve as effective localization features. This initial approach identifies four potential source locations, highlighting the feasibility of two-receiver source localization using traditional feature extraction methods. However, direct extraction can be challenging when mode overlaps occur, complicating the localization process. To address this, our work proposes a novel waveform-based method. This method leverages the consistent dispersion characteristics within isotropic materials, where each unique combination of mode arrival times and peak amplitudes constructs a distinct waveform. This distinctiveness overcomes the ambiguities associated with mode overlaps, significantly enhancing the method’s precision and robustness. Our approach adopts a data-driven strategy for waveform-based localization using variational autoencoder (VAE). VAE discerns waveform patterns for localization, while also addressing data uncertainties. The VAE’s encoder and decoder networks capture the localization process and the source’s influence on waveform generation, respectively, guiding latent variables to segregate waveforms by source in the latent space. The design of the learning process focuses on specific localization characteristics to enhance result explainability. Localization predictions are generated by projecting test waveforms, not included in the training set, onto a trained latent space. The prediction is determined using a nearest-neighbor approach based on the closest latent representation of a source. Validation with pencil-lead-break tests on a metallic pipe confirmed our method’s effectiveness, achieving an averaged 3D localization accuracy of 0.84.

Lee, Guan-Wei↗