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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 415 records · Page 23

Beta-Adrenergic Receptor Population is Up-Regulated in Chicken Skeletal Muscle Cells Treated with Forskolin

Skeletal muscle hypertrophy is promoted by in vivo administration of beta-adrenergic receptor (betaAR) agonists. These compounds presumably exert their physiological action through the betaAR, and alterations in the population of betaAR could potentially change the ability of the cell to respond to the betaAR agonists. Since the intracellular chemical signal generated by the betaAR is cyclic AMP (cAMP), experiments were initiated in primary chicken muscle cell cultures to determine if artificial elevation of intracellular cAMP by treatment with forskolin would alter the population of functional betaAR expressed on the surface of muscle cells. Chicken skeletal muscle cells after 7 days in culture were employed for the experiments because muscle cells have attained a steady state with respect to muscle protein metabolism at this stage. Cells were treated with 0-10 microM forskolin for a total of three days. At the end of the 1, 2, and 3 day treatment intervals, the concentration of cAMP and the betaAR population were measured. Receptor population was measured in intact muscle cell cultures as the difference between total binding of [H-3]CGP-12177 and non-specific binding of [H-3]CGP-12177 in the presence of 1 microM propranolol. Intracellular cAMP concentration was measured by radioimmunoassay. The concentration of cAMP in forskolin-treated cells increased up to 10-fold in a dose dependent manner. Increasing concentrations of forskolin also led to an increase in betaAR population, with a maximum increase of approximately 50% at 10 microM. This increase in PAR population was apparent after only 1 day of treatment, and the pattern of increase was maintained for all 3 days of the treatment period. Thus, increasing the intracellular concentration of cAMP leads to up-regulation of betaAR population. The effect of forskolin on the quantity and apparent synthesis rate of the heavy chain of myosin (mhc) were also investigated. A maximum increase of 50% in the quantity of mhc was observed at 0.2 microM forskolin, but higher concentrations of forskolin reduced the quantity of mhc back to control levels.

Bridge, K. Y.↗

Testing Results of the X-38 Crew Return Vehicle GPS Receiver

The X-38 Crew Return Vehicle (CRV) utilizes a Space Integrated GPS/INS (SIGI) sensor to obtain navigation and attitude knowledge. Testing and analysis at the NASA Goddard Space Flight Center Guidance, Navigation, and Control's GPS Lab was conducted in order to validate the development of SIGI GPS receiver attitude firmware. The modifications to the International Space Station (ISS) SIGI receiver that were completed to meet the CRV requirements will be presented. The CRV is designed to be used as a life-boat in case of an emergency evacuation from the ISS. The need to return the ISS crew in a timely manner places challenging performance requirements on the SIGI sensor. This paper will summarize the performance of the SIGI GPS receiver for the CRV. The ability to track the GPS signals at any initial attitude and the performance of the SIGI GPS-only solution during reentry are detailed in this paper. A discussion regarding the use of the Global Satellite Systems GPS Signal Generator in testing the SIGI sensor will provide insight into the GPS validation process used at NASA Goddard.

Simpson, James↗

A Diagnostic Analysis of the Kennedy Space Center LDAR Network: Data Characteristics - 1

An analytic framework is developed in which to analyze climatological VHF (66 MHz) radiation measurements taken by the Kennedy Space Center Lightning Detection and Ranging (LDAR) network. A 19 month noise-filtered sample of LDAR observations is examined using this framework. It is found that the climatological impulsive VHF source density as observed by LDAR falls off approximately 10 dB every 71 km of ground range away from the network centroid (a 31 km e-folding scale). The underlying vertical distribution of impulsive VHF sources is approximately normally distributed with a mean altitude of 9 km and a standard deviation of 2.7 km; this implies that the loss of below-horizon sources has a negligible effect on column-integrated source densities within a 200 km ground range. At medium to far ranges, location errors are primarily radial and have a slightly asymmetric distribution whose standard deviation increases as r(exp 2). Error moments estimated from observed lightning are significantly higher than those from aircraft-based signal generator or analytic estimates. LDAR bulk flash detection efficiency is predicted to be above 90% to 94-113 km range from the network centroid and to fall below 10% at ranges greater than 200-240 km.

Boccippio, D. J.↗

Regulation of Osteoblast Survival by the Extracellular Matrix and Gravity

Spaceflight adversely affects the skeleton, posing a substantial risk to astronaut's health during long duration missions. The reduced bone mass observed in growing animals following spaceflight is due at least in part to inadequate bone formation by osteoblasts. Thus, it is of central importance to identify basic cellular mechanisms underlying normal bone formation. The fundamental ideas underlying our research are that interactions between extracellular matrix proteins, integrin adhesion receptors, cytoplasmic signaling and cytoskeletal proteins are key ingredients for the proper functioning of osteoblasts, and that gravity impacts these interactions. As an in vitro model system we used primary fetal rat calvarial cells which faithfully recapitulate osteoblast differentiation characteristically observed in vivo. We showed that specific integrin receptors ((alpha)3(beta)1), ((alpha)5(beta)1), ((alpha)8(betal)1) and extracellular matrix proteins (fibronectin, laminin) were needed for the differentiation of immature osteoblasts. In the course of maturation, cultured osteoblasts switched from depending on fibronectin and laminin for differentiation to depending on these proteins for their very survival. Furthermore, we found that manipulating the gravity vector using ground-based models resulted in activation of key intracellular survival signals generated by integrin/extracellular matrix interactions. We are currently testing the in vivo relevance of some of these observations using targeted transgenic technology. In conclusion, mechanical factors including gravity may participate in regulating survival via cellular interactions with the extracellular matrix. This leads us to speculate that microgravity adversely affects the survival of osteoblasts and contributes to spaceflight-induced osteoporosis.

Globus. Ruth K.↗

Simulated Performance of the Orbiting Wide-angle Light Collectors (OWL) Experiment

The Orbiting Wide-angle Light collectors (OWL) experiment is in NASA's mid-term strategic plan and will stereoscopically image, from equatorial orbit, the air fluorescence signal generated by airshowers induced by the ultrahigh energy (E greater than few x 10(exp 19) eV) component of the cosmic radiation. The use of a space-based platform enables an extremely large event acceptance aperture and thus will allow a high statistics measurement of these rare events. Detailed Monte Carlo simulations are required to quantify the physics potential of the mission as well as optimize the instrumental parameters. This paper reports on the results of the GSFC Monte Carlo simulation for two different, OWL instrument baseline designs. These results indicate that, assuming a continuation of the cosmic ray spectrum (theta approximately E(exp -2.75), OWL could have an event rate of 4000 events/year with E greater than or equal to 10(exp 20) eV. Preliminary results, based upon these Monte Carlo simulations, indicate that events can be accurately reconstructed in the detector focal plane arrays for the OWL instrument baseline designs under consideration.

Krizmanic, J. F.↗

Implementation of Adaptive Digital Controllers on Programmable Logic Devices

Much has been made of the capabilities of FPGA's (Field Programmable Gate Arrays) in the hardware implementation of fast digital signal processing (DSP) functions. Such capability also makes and FPGA a suitable platform for the digital implementation of closed loop controllers. There are myriad advantages to utilizing an FPGA for discrete-time control functions which include the capability for reconfiguration when SRAM- based FPGA's are employed, fast parallel implementation of multiple control loops and implementations that can meet space level radiation tolerance in a compact form-factor. Other researchers have presented the notion that a second order digital filter with proportional-integral-derivative (PID) control functionality can be implemented in an FPGA. At Marshall Space Flight Center, the Control Electronics Group has been studying adaptive discrete-time control of motor driven actuator systems using digital signal processor (DSF) devices. Our goal is to create a fully digital, flight ready controller design that utilizes an FPGA for implementation of signal conditioning for control feedback signals, generation of commands to the controlled system, and hardware insertion of adaptive control algorithm approaches. While small form factor, commercial DSP devices are now available with event capture, data conversion, pulse width modulated outputs and communication peripherals, these devices are not currently available in designs and packages which meet space level radiation requirements. Meeting our goals requires alternative compact implementation of such functionality to withstand the harsh environment encountered on spacecraft. Radiation tolerant FPGA's are a feasible option for reaching these goals.

Gwaltney, David A.↗

Direct Fault Tolerant RLV Altitude Control: A Singular Perturbation Approach

In this paper, we present a direct fault tolerant control (DFTC) technique, where by "direct" we mean that no explicit fault identification is used. The technique will be presented for the attitude controller (autopilot) for a reusable launch vehicle (RLV), although in principle it can be applied to many other applications. Any partial or complete failure of control actuators and effectors will be inferred from saturation of one or more commanded control signals generated by the controller. The saturation causes a reduction in the effective gain, or bandwidth of the feedback loop, which can be modeled as an increase in singular perturbation in the loop. In order to maintain stability, the bandwidth of the nominal (reduced-order) system will be reduced proportionally according to the singular perturbation theory. The presented DFTC technique automatically handles momentary saturations and integrator windup caused by excessive disturbances, guidance command or dispersions under normal vehicle conditions. For multi-input, multi-output (MIMO) systems with redundant control effectors, such as the RLV attitude control system, an algorithm is presented for determining the direction of bandwidth cutback using the method of minimum-time optimal control with constrained control in order to maintain the best performance that is possible with the reduced control authority. Other bandwidth cutback logic, such as one that preserves the commanded direction of the bandwidth or favors a preferred direction when the commanded direction cannot be achieved, is also discussed. In this extended abstract, a simplistic example is proved to demonstrate the idea. In the final paper, test results on the high fidelity 6-DOF X-33 model with severe dispersions will be presented.

Zhu, J. J.↗

Implementation of Adaptive Digital Controllers on Programmable Logic Devices

Much has been made of the capabilities of Field Programmable Gate Arrays (FPGA's) in the hardware implementation of fast digital signal processing functions. Such capability also makes an FPGA a suitable platform for the digital implementation of closed loop controllers. Other researchers have implemented a variety of closed-loop digital controllers on FPGA's. Some of these controllers include the widely used Proportional-Integral-Derivative (PID) controller, state space controllers, neural network and fuzzy logic based controllers. There are myriad advantages to utilizing an FPGA for discrete-time control functions which include the capability for reconfiguration when SRAM- based FPGA's are employed, fast parallel implementation of multiple control loops and implementations that can meet space level radiation tolerance requirements in a compact form-factor. Generally, a software implementation on a Digital Signal Processor (DSP) device or microcontroller is used to implement digital controllers. At Marshall Space Flight Center, the Control Electronics Group has been studying adaptive discrete-time control of motor driven actuator systems using DSP devices. While small form factor, commercial DSP devices are now available with event capture, data conversion, Pulse Width Modulated (PWM) outputs and communication peripherals, these devices are not currently available in designs and packages which meet space level radiation requirements. In general, very few DSP devices are produced that are designed to meet any level of radiation tolerance or hardness. An alternative is required for compact implementation of such functionality to withstand the harsh environment encountered on spacemap. The goal of this effort is to create a fully digital, flight ready controller design that utilizes an FPGA for implementation of signal conditioning for control feedback signals, generation of commands to the controlled system, and hardware insertion of adaptive-control algorithm approaches. Radiation tolerant FPGA's are a feasible option for reaching this goal.

Gwaltney, David A.↗

Implementation of Adaptive Digital Controllers on Programmable Logic Devices

Much has been made of the capabilities of FPGA's (Field Programmable Gate Arrays) in the hardware implementation of fast digital signal processing. Such capability also makes an FPGA a suitable platform for the digital implementation of closed loop controllers. Other researchers have implemented a variety of closed-loop digital controllers on FPGA's. Some of these controllers include the widely used proportional-integral-derivative (PID) controller, state space controllers, neural network and fuzzy logic based controllers. There are myriad advantages to utilizing an FPGA for discrete-time control functions which include the capability for reconfiguration when SRAM-based FPGA's are employed, fast parallel implementation of multiple control loops and implementations that can meet space level radiation tolerance requirements in a compact form-factor. Generally, a software implementation on a DSP (Digital Signal Processor) or microcontroller is used to implement digital controllers. At Marshall Space Flight Center, the Control Electronics Group has been studying adaptive discrete-time control of motor driven actuator systems using digital signal processor (DSP) devices. While small form factor, commercial DSP devices are now available with event capture, data conversion, pulse width modulated (PWM) outputs and communication peripherals, these devices are not currently available in designs and packages which meet space level radiation requirements. In general, very few DSP devices are produced that are designed to meet any level of radiation tolerance or hardness. The goal of this effort is to create a fully digital, flight ready controller design that utilizes an FPGA for implementation of signal conditioning for control feedback signals, generation of commands to the controlled system, and hardware insertion of adaptive control algorithm approaches. An alternative is required for compact implementation of such functionality to withstand the harsh environment encountered on spacecraft. Radiation tolerant FPGA's are a feasible option for reaching this goal.

Gwaltney, David A.↗

A Step Response Based Mixed-Signal BIST Approach for Continuous-time Linear Circuits

A new Mixed-Signal Built-in self-test approach that is based upon the step response of a reconfigurable (or multifunction) analog block is presented in this paper. The technique requires the overlapping step response of the Circuit Under Test (CUT) for two circuit configurations. Each configuration can be realized by changing the topology of the CUT or by sampling two CUT nodes with differing step responses. The technique can effectively detect both soft and hard faults and does not require an analog-to-digital converter (ADC) and/or digital-to-analog converter(DAC). It also does not require any precision voltage sources or comparators. This approach does not require any additional analog circuits to realize the test signal generator and sample circuits. The paper is concluded with the application of the proposed approach to a circuit found in the work of Epstein et al and two ITC 97 analog benchmark circuits.

Walker, Alvernon↗

A Step Response Based Mixed-Signal BIST Approach

A new Mixed-Signal Built-in Self-test approach that is based upon the step response of a reconfigurable (or multifunction) analog block is presented in this paper. The technique requires the overlapping step response of the Circuit Under Test (CUT) for two circuit configurations. Each configuration can be realized by changing the topology of the CUT or by sampling two CUT nodes with differing step responses. The technique can effectively detect both soft and hard faults and does not require an analog-to-digital converter (ADC) and/or digital-to-analog converter( DAC). It also does not require any precision voltage sources or comparators. The approach does not require any additional analog circuits to realize the test signal generator and a two input analog multiplexer for CUT test node sampling. The paper is concluded with the application of the proposed approach to a circuit found in the work of Epstein et a1 and two ITC 97 analog benchmark circuits.

Walker, Alvernon↗

Electrochemical and Hydrodynamic Interferences on the Performances of an Oxygen Microsensor with Built-in Electrochemical Microactuator

A concept of novel electrochemical in situ self-calibration technique for an oxygen microsensor has been proposed to devise a convenient calibration method without an externally coupled apparatus. Systemic investigations on the influences of various electrochemical (pH) and hydrodynamic (solution stirring) conditions on the proposed microsensor performances are presented. The results suggest that: 1) The calibrating microenvironments can be manipulated with carefully engineered sensor designs and optimized generating signals; 2) The external oxygen permeable membrane is needed to minimize the electrochemical and hydrodynamic interferences.

Kim, Chang-Soo↗

Magnetic and Langmuir Probe Measurements on the Plasmoid Thruster Experiment (PTX)

The Plasmoid Thruster Experiment (PTX) operates by inductively producing plasmoids in a conical theta-pinch coil and subsequently ejecting them at high velocity. An overview of PTX is described in a companion paper. The shape and magnetic field structure of the translating plasmoids will be measured with of an array of inductive magnetic field probes. Six sets of two B-dot probes (for a total of twelve probes) have been constructed for measuring B(sub z) and B(sub theta), the axial and azimuthal components of the magnetic field. The probes were calibrated with a Helmholtz coil, driven alternately by a high-voltage pulser or a signal generator. The probes are wound on a G-10 form, and have an average (calibrated) NA of 9.37 x 10(exp -5) square meters, where N is the number of turns and A is cross-sectional area. The frequency response of the probes was measured over the range from 1 kHz to 10 MHZ. The electron number density n(sub e), electron temperature T(sub e) and velocity v will be determined from measurements taken with a quadruple Langmuir probe, situated in the exhaust chamber. Three of the four probes on the quadruple probe sample the current-voltage characteristic, and from this yield measurements of T(sub e) and n(sub e). The fourth probe provides a measurement of plasma flow velocity. A 6-inch long alumina rod, hollowed with four holes to house the probe wires, is being used to construct the quadruple probe. A variety of propellants will be used, including hydrogen, nitrogen and argon. From the measurements of the plasmoid mass, density, temperature, and velocity, the basic propulsion characteristics of PTX will be evaluated.

Koelfgen, Syri J.↗

Magnetic and Langmuir Probe Measurements on the Plasmoid Thruster Experiment (PTX)

The Plasmoid Thruster Experiment (PTX) operates by inductively producing plasmoids in a conical theta-pinch coil and ejecting them at high velocity. A plasmoid is a plasma with an imbedded closed magnetic field structure. The shape and magnetic field structure of the translating plasmoids have been measured with of an array of magnetic field probes. Six sets of two B-dot probes were constructed for measuring B(sub z) and B(sub theta), the axial and azimuthal components of the magnetic field. The probes are wound on a square G10 form, and have an average (calibrated) NA of 9.37 x l0(exp -5) square meters, where N is the number of turns and A is the cross-sectional area. The probes were calibrated with a Helmholtz coil, driven by a high-voltage pulser to measure NA, and by a signal generator to determine the probe's frequency response. The plasmoid electron number density n(sub e) electron temperature T(sub e), and velocity ratio v/c(sub m), (where v is the bulk plasma flow velocity and c(sub m), is the ion thermal speed) have also been measured with a quadruple Langmuir probe. The Langmuir probe tips are 10 mm long, 20-mil diameter stainless steel wire, housed in a 6-inch long 4-bore aluminum rod. Measurements on PTX with argon and hydrogen from the magnetic field probes and quadruple Langmuir probe will be presented in this paper.

Koelfgen, Syri J.↗

Health Monitoring System for Car Seat

A health monitoring system for use with a child car seat has sensors mounted in the seat to monitor one or more health conditions of the seat's occupant. A processor monitors the sensor's signals and generates status signals related to the monitored conditions. A transmitter wireless transmits the status signals to a remotely located receiver. A signaling device coupled to the receiver produces at least one sensory (e.g., visual, audible, tactile) output based on the status signals.

Susan Vinz Elrod↗

Skeletal phenotype of growing transgenic mice that express a function-perturbing form of beta1 integrin in osteoblasts

Skeletal modeling entails the deposition of large amounts of extracellular matrix (ECM) to form structures tailored to withstand increasing mechanical loads during rapid growth. Specific ECM molecules bind to integrin receptors on the cell surface, thereby triggering a cascade of signaling events that affect critical cell functions. To evaluate the role of integrins during skeletal growth, transgenic mice were engineered to express a function-perturbing fragment of beta1 integrin consisting of the transmembrane domain and cytoplasmic tail under the control of the osteocalcin promoter (TG mice). Thus, transgene expression was targeted to mature cells of the osteoblast lineage, and herein we show that cultured cells resembling osteocytes from 90-day-old TG mice display impaired adhesion to collagen I, a ligand for beta1 integrin. To determine the influence of beta1 integrin on bones that are responsible for providing structural support during periods of rapid growth, we examined the phenotype of the appendicular skeleton in TG mice compared to wild type (WT) mice. According to radiographs, bones from mice of both genotypes between 14 and 90 days of age appeared similar in gross structure and density, although proximal tibiae from 35-90 days old TG mice were less curved than those of WT mice (72-92% TG/WT). Although there were only mild and transient differences in absolute bone mass and strength, once normalized to body mass, the tibial dry mass (79.1% TG/WT females), ash mass (78.5% TG/WT females), and femoral strength in torsion (71.6% TG/WT females) were reduced in TG mice compared to WT mice at 90 days of age. Similar effects of genotype on bone mass and curvature were observed in 1-year-old retired breeders, indicating that these phenotypic differences between TG and WT mice were stable well into adulthood. Effects of genotype on histomorphometric indices of cancellous bone turnover were minimal and evident only transiently during growth, but when present they demonstrated differences in osteoblast rather than osteoclast parameters. Together, these results suggest that integrin signals generated during growth enhance the acquisition of a skeletal mass, structure, and strength to withstand the mechanical loads generated by weight-bearing.

Antigens, CD29/genetics/metabolism↗

Multichannel Error Correction Code Decoder

NASA Lewis Research Center's Digital Systems Technology Branch has an ongoing program in modulation, coding, onboard processing, and switching. Recently, NASA completed a project to incorporate a time-shared decoder into the very-small-aperture terminal (VSAT) onboard-processing mesh architecture. The primary goal was to demonstrate a time-shared decoder for a regenerative satellite that uses asynchronous, frequency-division multiple access (FDMA) uplink channels, thereby identifying hardware and power requirements and fault-tolerant issues that would have to be addressed in a operational system. A secondary goal was to integrate and test, in a system environment, two NASA-sponsored, proof-of-concept hardware deliverables: the Harris Corp. high-speed Bose Chaudhuri-Hocquenghem (BCH) codec and the TRW multichannel demultiplexer/demodulator (MCDD). A beneficial byproduct of this project was the development of flexible, multichannel-uplink signal-generation equipment.

Source record↗

Waveguide Power Combiner Demonstration for Multiple High Power Millimeter Wave TWTAs

NASA is presently developing nuclear reactor technologies, under Project Prometheus, which will provide spacecraft with greatly increased levels of sustained onboard power and thereby dramatically enhance the capability for future deep space exploration. The first mission planned for use of this high power technology is the Jupiter Icy Moons Orbiter (JIMO). In addition to electric propulsion and science, there will also be unprecedented onboard power available for deep space communications. A 32 GHz transmitter with 1 kW of RF output power is being considered to enable the required very high data transmission rates. One approach to achieving the 1 kW RF power, now being investigated at NASA GRC, is the possible power combining of a number of 100-1 50 W TWTs now under development. The work presented here is the results of a proof-of-concept demonstration of the power combining Ka-band waveguide circuit design and test procedure using two Ka- band TWTAs (Varian model VZA6902V3 and Logimetrics model A440/KA-1066), both of which were previously employed in data uplink evaluation terminals at 29.36 GHz for the NASA Advanced Communications Technology Satellite (ACTS) program. The characterization of the individual TWTAs and power combining demonstration were done over a 500 MHz bandwidth from 29.1 to 29.6 GHz to simulate the Deep Space Network (DSN) bandwidth of 3 1.8 to 32.3 GHz. Figures 1-3 show some of the power transfer and gain measurements of the TWTAs using a swept signal generator (Agilent 83640b) for the RF input. The input and output powers were corrected for circuit insertion losses due to the waveguide components. The RF saturated powers of both ACTS TWTAs were on the order of 120 W, which is comparable to the expected output powers of the 32 GHz TWTs. Additional results for the individual TWTAs will be presented (AM/AM, AM/PM conversion and gain compression), some of which were obtained from swept frequency and power measurements using a vector network analyzer. The results for the power combining demonstration as well as a more detailed description of the power combining test circuit and test procedure will also be presented.

Wintucky, Edwin G.↗