Problems in the measurement of tissue respiration with the oxygen electrode
Tissue respiration measurement with membrane- covered oxygen electrode, discussing effects of electrode deterioration and diffusion artifacts on accuracy
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Tissue respiration measurement with membrane- covered oxygen electrode, discussing effects of electrode deterioration and diffusion artifacts on accuracy
Anchorage dependent cell cultures in fluidized beds are tested. Feasibility calculations indicate the allowed parameters and estimate the shear stresses therein. In addition, the diffusion equation with first order reaction is solved for the spherical shell (double bubble) reactor with various constraints.
The aim of this study is to find a reliable numerical algorithm to calculate thermal design sensitivities of a transient problem with discontinuous derivatives. The thermal system of interest is a transient heat conduction problem related to the curing process of a composite laminate. A logical function which can smoothly approximate the discontinuity is introduced to modify the system equation. Two commonly used methods, the adjoint variable method and the direct differentiation method, are then applied to find the design derivatives of the modified system. The comparisons of numerical results obtained by these two methods demonstrate that the direct differentiation method is a better choice to be used in calculating thermal design sensitivity.
The PI (Cranmer) and Co-I (A. van Ballegooijen) made significant progress toward the goal of building a "unified model" of the dominant physical processes responsible for the acceleration of the solar wind. The approach outlined in the original proposal comprised two complementary pieces: (1) to further investigate individual physical processes under realistic coronal and solar wind conditions, and (2) to extract the dominant physical effects from simulations and apply them to a one-dimensional and time-independent model of plasma heating and acceleration. The accomplishments in the report period are thus divided into these two categories: 1a. Focused Study of Kinetic MHD Turbulence. We have developed a model of magnetohydrodynamic (MHD) turbulence in the extended solar corona that contains the effects of collisionless dissipation and anisotropic particle heating. A turbulent cascade is one possible way of generating small-scale fluctuations (easy to dissipate/heat) from a pre-existing population of low-frequency Alfven waves (difficult to dissipate/heat). We modeled the cascade as a combination of advection and diffusion in wavenumber space. The dominant spectral transfer occurs in the direction perpendicular to the background magnetic field. As expected from earlier models, this leads to a highly anisotropic fluctuation spectrum with a rapidly decaying tail in the parallel wavenumber direction. The wave power that decays to high enough frequencies to become ion cyclotron resonant depends on the relative strengths of advection and diffusion in the cascade. For the most realistic values of these parameters, though, there is insufficient power to heat protons and heavy ions. The dominant oblique waves undergo Landau damping, which implies strong parallel electron heating. We thus investigated the nonlinear evolution of the electron velocity distributions (VDFs) into parallel beams and discrete phase-space holes (similar to those seen in the terrestrial magnetosphere) which are an alternate means of heating protons via stochastic interactions similar to particle-particle collisions. 1b. Focused Study of the Multi-Mode Detailed Balance Formalism. The PI began to explore the feasibility of using the "weak turbulence," or detailed-balance theory of Tsytovich, Melrose, and others to encompass the relevant physics of the solar wind. This study did not go far, however, because if the "strong" MHD turbulence discussed above is a dominant player in the wind's acceleration region, this formalism is inherently not applicable to the corona. We will continue to study the various published approaches to the weak turbulence formalism, especially with an eye on ways to parameterize nonlinear wave reflection rates. 2. Building the Unified Model Code Architecture. We have begun developing the computational model of a time-steady open flux tube in the extended corona. The model will be "unified" in the sense that it will include (simultaneously for the first time) as many of the various proposed physical processes as possible, all on equal footing. To retain this generality, we have formulated the problem in two interconnected parts: a completely kinetic model for the particles, using the Monte Carlo approach, and a finite-difference approach for the self-consistent fluctuation spectra. The two codes are run sequentially and iteratively until complete consistency is achieved. The current version of the Monte Carlo code incorporates gravity, the zero-current electric field, magnetic mirroring, and collisions. The fluctuation code incorporates WKJ3 wave action conservation and the cascade/dissipation processes discussed above. The codes are being run for various test problems with known solutions. Planned additions to the codes include prescriptions for nonlinear wave steepening, kinetic velocity-space diffusion, and multi-mode coupling (including reflection and refraction).
A review is presented of various rotordynamic problems which have been encountered and eliminated in developing the current flight engines, and continuing subsynchronous problems which are being encountered in developing a 109% power level engine. The basic model for the High Pressure Oxygen Turbopump (HPOTP) of the SSME including the structural dynamic model for the rotor and housing and component models for the liquid and gas seals, turbine-clearance excitation forces, and impeller-diffuser forces are discussed. Results from a linear model are used to examine the synchronous response and stability characteristics of the HPOTP, examining bearing load and stability problems associated with the second critical speed. Various seal modifications are examined and shown to have favorable consequences with respect to bearing reactions and stability.
The diffusive acceleration of highly relativistic particles at a shock is reconsidered. Using the same physical assumptions as Blandford and Ostriker (1978), but dropping the restriction to nonrelativistic shock velocities, the authors find approximate solutions of the particle kinetic equation by generalizing the diffusion approximation to higher order terms in the anisotropy of the particle distribution. The general solution of the transport equation on either side of the shock is constructed, which involves the solution of an eigenvalue problem. By matching the two solutions at the shock, the spectral index of the resulting power law is found by taking into account a sufficiently large number of eigenfunctions. Low-order truncation corresponds to the standard diffusion approximation and to a somewhat more general method described by Peacock (1981). In addition to the energy spectrum, the method yields the angular distribution of the particles and its spatial dependence.
Diffusion bonding method does not affect the mechanical properties of steel nor the strength of Teflon. It alleviates problems of adhesive outgassing, radiation damage, and delamination.
A generalization of Bucy's (1965) representation theorem is obtained under very weak hypotheses. The generalized theorem is shown to play the same role in the case of general optimal estimation for an arbitrary random process as does the Bucy theorem in the case of optimal filtering for a diffusion process. At least for the models considered, the possibility is pointed out to reduce all sequential estimation problems to the problem of filtering. Hence, filtering theory is seen to represent the core of estimation theory, and is believed to define the direction in which future research should be focused.
The transient cooldown of a gray, absorbing, isotropic scattering, emitting, and conducting medium bounded by gray, diffusely emitting and reflecting parallel plates is considered. Numerical solutions are obtained for the initial boundary-value problem with a discontinuous decrease in temperature at one boundary. The quasi-steady equation of radiative transfer is solved using Gaussian quadrature and a matrix eigenvector technique together with explicit numerical solution of the unsteady energy equation. Temperature and energy flux distributions are presented for variations of optical thickness, boundary emissivity, albedo, and conduction-radiation parameter.
Recently measured positron and negatron spectra are discussed with regard to the problem of solar modulation. At energies above 180 MeV, the spherically symmetric Fokker-Planck equation with a diffusion coefficient proportional to particle rigidity provides reasonable fits to both the positron and total electron data. At energies below 180 MeV, the data are consistent with a continuation of the same diffusion coefficient and a local source of negatrons or with a change in the diffusion coefficient to a constant value.
The fabrication of boron filaments and the production of composite materials consisting of boron filaments and organic or metallic matrices are discussed. Problem involving the use of tungsten substrates in the filament fabrication process, the protection of boron fibers with diffusion barrier cladings, and the application of alloy additives in the matrix to lessen the effects of diffusion are considered. Data on the kinetics of the boron fiber/matrix interaction at high temperatures, and the influence of the fiber/matrix interaction on the mechanical properties of the composite are presented.
A system of computer programs is being developed to analyse and predict the complex flow fields found in hydrogen-fueled scramjet combustors. Each program is designed to solve the governing equation system for the type of flow present in a particular combustor region. A two-dimensional parabolic program has been found to be valuable in the development and experimental evaluation of turbulence and chemistry models for supersonic flow, and in the development of a program to model supersonic flow downstream of the fuel injection struts by means of solutions to the three-dimensional parabolic Navier-Stokes equations and species equations. A partially elliptic code has been derived to account for local subsonic flow regions, and fully elliptic programs have been developed by the consideration of streamwise diffusion effects for the recirculating flow fields near transverse fuel injectors. The programs are currently being applied to problems of scramjet engine development.
The results are presented of a careful study of finite-difference solutions to the problem of cosmic-ray transport, including pitch-angle scattering. In contrast to some recent studies, the diffusion approximation is confirmed in cases where the scattering mean free path is small compared with other length scales. The reasons for the discrepancy with the conclusions of Gombosi and Owens are discussed.
A nonlinear reaction-diffusion equation and some additional constraints are derived which describe the time-dependent behavior of the temperature structure of the plasma in coronal loops. The equation is analyzed using nonlinear diffusion asymptotics, in particular singular perturbation techniques, and the results are interpreted in the context of the physical problem of the thermal stability and temporal behavior of the plasma. The results are consistent with the possibility of cyclic thermal behavior of the plasma, as suggested by Kuin and Martens (1982).
It was shown that the modified flow pass method possesses considerable effectiveness, both in the case when the coefficient of diffusion changes severely in the examined region and in the case when diffusion is the prevalent process, as compared with chemical reactions. The case when a regular pass proves inapplicable, or applicable in a limited interval of the decisive parameters, was examined.
Numerical experiments for the SONIC schemes on 2D inviscid, compressible, steady, and unsteady problems are presented. These schemes belong to a new class of uniformly second-order accurate nonoscillatory schemes introduced by Huynh, with the well known UNO2 scheme of Harten and Osher being the most 'diffusive' in this class. The SONIC schemes can also be considered as uniformly second order accurate extensions of the popular TVD schemes. For simplicity, a MUSCL approach for spatial discretization and a Runge-Kutta method for time integration are used. Test problems include steady oblique shock reflection and the well known unsteady double Mach reflection problem. Results confirm that the SONIC schemes are more accurate than their TVD counterparts.
The problem of turbulent flow heat transfer in a concentric circular tube annulus with fully developed velocity profile and constant heat rate per unit of length is considered. Experimentally obtained solutions are presented for the thermal entry length for a fluid with P(sub r) = 0·7. Asymptotic solutions (fully developed velocity and temperature profiles) are developed for a wide range of radius ratio, Reynolds number, and Prandtl number. The solutions are based on empirical velocity and eddy diffusivity profiles, and the validity of the solutions is demonstrated experimentally for P(sub r) = 0·7. A superposition method is demonstrated for solving the problem of asymmetric heating from the two surfaces of an annulus, and experimental data on asymmetric heating are presented which are in excellent agreement with the analysis. This paper is the third in a series (1, 2) culminating a four year study of heat transfer in annular passages.
The study of flame-vortex interactions provides one of the means to better understand turbulent combustion, and allows for canonical configurations that contain the fundamental elements found in turbulent flames, These include concentrated vorticity, entrainment and mixing, strain and nonequilibrium phenomena, diffusion and differential diffusion, partial premixing and diluent effects, and heat release effects. In flame- vortex configurations, these fundamental elements can be studied under more controlled conditions than is possible in direct investigations of turbulent flames. Since the paper of Marble, the problem of the flame-vortex interaction has received considerable attention theoretically, numerically and experimentally. Several configurations exist for study of the premixed flame/vortex ring interaction but more limited results have been obtained to date for the diffusion flame/vortex ring case. The setup of Chen and Dahm, which is conceptually similar to that of Karagozian and Manda and Karagozian, Suganuma and Strom where the ring is composed of fuel and air and combustion begins during the ring formation process, is used in the current study. However, it is essential to conduct the experiments in microgravity to remove the asymmetries caused by buoyancy and thus obtain highly symmetric and repeatable interactions. In previous studies it was found that the flame structure of the vortex ring was similar to that obtained analytically by Karagozian and Manda. Dilution of propane with nitrogen led mainly to a reduction in flame luminosities, flame burnout times were affected by both fuel volumes and amount of dilution, and a simple model of the burnout times was developed. In this paper, a discussion on reacting ring displacement and flame burnout time will be given, and the flame structures of vortex rings containing ethane and air will be compared to those of propane reacting in air.