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Life Sciences Accomplishments 1994

The NASA Life and Biomedical Sciences and Applications Division (LBSAD) serves the Nation's life sciences community by managing all aspects of U.S. space-related life sciences research and technology development. The activities of the Division are integral components of the Nation's overall biological sciences and biomedical research efforts. However, NASA's life sciences activities are unique, in that space flight affords the opportunity to study and characterize basic biological mechanisms in ways not possible on Earth. By utilizing access to space as a research tool, NASA advances fundamental knowledge of the way in which weightlessness, radiation, and other aspects of the space-flight environment interact with biological processes. This knowledge is applied to procedures and technologies that enable humans to live and work in and explore space and contributes to the health and well-being of people on Earth. The activities of the Division are guided by the following three goals: Goal 1) Use microgravity and other unique aspects of the space environment to enhance our understanding of fundamental biological processes. Goal 2) Develop the scientific and technological foundations for supporting exploration by enabling productive human presence in space for extended periods. Goal 3) Apply our unique mission personnel, facilities, and technology to improve education, the quality of life on Earth, and U.S. competitiveness. The Division pursues these goals with integrated ground and flight programs involving the participation of NASA field centers, industry, and universities, as well as interactions with other national agencies and NASA's international partners. The published work of Division-sponsored researchers is a record of completed research in pursuit of these goals. During 1993, the LBSAD instituted significant changes in its experiment solicitation and peer review processes. For the first time, a NASA Research Announcement (NRA) was released requesting proposals for ground-based and flight research for all programs. Areas of particular interest to NASA were defined Proposals due April 29, 1994, will be peer reviewed - externally for scientific merit. This annual NRA process is now the mechanism for recruiting both extramural and intramural investigations. As an overview of LBSAD activities in 1993, this accomplishments document covers each of the major organizational components of the Division and the accomplishments of each. The second section is a review of the Space Life Sciences Research programs Space Biology, Space Physiology and Countermeasures, Radiation Health, Environmental Health, Space Human Factors, Advanced Life Support, and Global Monitoring and Disease Prediction, The third section, Research in Space Flight, describes the substantial contributions of the Spacelab Life Sciences 2 (SLS-2) mission to life sciences research and the significant contributions of the other missions flown in 1993, along with plans for future missions. The Division has greatly expanded and given high priority to its Education and Outreach Programs, which are presented in the fourth section. The fifth and final section, Partners for Space, shows the Divisions Cooperative efforts with other national and international agencies to achieve common goals, along with the accomplishments of joint research and analysis programs.

Burnell, Mary Lou↗

NASA/Navy Benchmarking Exchange (NNBE). Volume 1. Interim Report. Navy Submarine Program Safety Assurance

The NASA/Navy Benchmarking Exchange (NNBE) was undertaken to identify practices and procedures and to share lessons learned in the Navy's submarine and NASA's human space flight programs. The NNBE focus is on safety and mission assurance policies, processes, accountability, and control measures. This report is an interim summary of activity conducted through October 2002, and it coincides with completion of the first phase of a two-phase fact-finding effort.In August 2002, a team was formed, co-chaired by senior representatives from the NASA Office of Safety and Mission Assurance and the NAVSEA 92Q Submarine Safety and Quality Assurance Division. The team closely examined the two elements of submarine safety (SUBSAFE) certification: (1) new design/construction (initial certification) and (2) maintenance and modernization (sustaining certification), with a focus on: (1) Management and Organization, (2) Safety Requirements (technical and administrative), (3) Implementation Processes, (4) Compliance Verification Processes, and (5) Certification Processes.

SUBSAFE PROGRAM↗

An Electronic Workshop on the Performance Seeking Control and Propulsion Controlled Aircraft Results of the F-15 Highly Integrated Digital Electronic Control Flight Research Program

Flight research for the F-15 HIDEC (Highly Integrated Digital Electronic Control) program was completed at NASA Dryden Flight Research Center in the fall of 1993. The flight research conducted during the last two years of the HIDEC program included two principal experiments: (1) performance seeking control (PSC), an adaptive, real-time, on-board optimization of engine, inlet, and horizontal tail position on the F-15; and (2) propulsion controlled aircraft (PCA), an augmented flight control system developed for landings as well as up-and-away flight that used only engine thrust (flight controls locked) for flight control. In September 1994, the background details and results of the PSC and PCA experiments were presented in an electronic workshop, accessible through the Dryden World Wide Web (http://www.dfrc.nasa.gov/dryden.html) and as a compact disk.

Powers, Sheryll Goecke↗

The Columbia Accident Investigation and The NASA Glenn Ballistic Impact Laboratory Contributions Supporting NASA's Return to Flight

On February 1, 2003, the Space Shuttle Columbia broke apart during reentry, resulting in loss of the vehicle and its seven crewmembers. For the next several months, an extensive investigation of the accident ensued involving a nationwide team of experts from NASA, industry, and academia, spanning dozens of technical disciplines. The Columbia Accident Investigation Board (CAIB), a group of experts assembled to conduct an investigation independent of NASA, concluded in August, 2003 that the most likely cause of the loss of Columbia and its crew was a breach in the left wing leading edge Reinforced Carbon-Carbon (RCC) thermal protection system initiated by the impact of thermal insulating foam that had separated from the orbiters external fuel tank 81 seconds into the mission's launch. During reentry, this breach allowed superheated air to penetrate behind the leading edge and erode the aluminum structure of left wing, which ultimately led to the breakup of the orbiter. The findings of the CAIB were supported by ballistic impact tests, which simulated the physics of External Tank Foam impact on the RCC wing leading edge material. These tests ranged from fundamental material characterization tests to full-scale Orbiter Wing Leading Edge tests. Following the accident investigation, NASA spent the next 18 months focused on returning the shuttle safely to flight. In order to fully evaluate all potential impact threats from the many debris sources on the Space Shuttle during ascent, NASA instituted a significant impact testing program. The results from these tests led to the validation of high-fidelity computer models, capable of predicting actual or potential Shuttle impact events, were used in the certification of STS-114, NASA s Return to Flight Mission, as safe to fly. This presentation will provide a look into the inner workings of the Space Shuttle and a behind the scenes perspective on the impact analysis and testing done for the Columbia Accident Investigation and NASA's Return to Flight programs. In addition, highlights from recent Shuttle missions are presented.

Melis, Matthew E.↗

Nuclear Thermal Propulsion (NTP) Development Activities at the NASA Marshall Space Flight Center - 2006 Accomplishments

In 2005-06, the Prometheus program funded a number of tasks at the NASA-Marshall Space Flight Center (MSFC) to support development of a Nuclear Thermal Propulsion (NTP) system for future manned exploration missions. These tasks include the following: 1. NTP Design Develop Test & Evaluate (DDT&E) Planning 2. NTP Mission & Systems Analysis / Stage Concepts & Engine Requirements 3. NTP Engine System Trade Space Analysis and Studies 4. NTP Engine Ground Test Facility Assessment 5. Non-Nuclear Environmental Simulator (NTREES) 6. Non-Nuclear Materials Fabrication & Evaluation 7. Multi-Physics TCA Modeling. This presentation is a overview of these tasks and their accomplishments

Ballard, Richard O.↗

From Wind Tunnels to Flight Vehicles: Visualization and quantitative measurements supporting NASA’s space program

NASA’s Space Launch System (SLS) and Orion Crew Module have been studied in wind tunnels using the planar laser-induced fluorescence (PLIF) technique for flow visualization and quantitative thermometry and in flight using high-resolution imagery and quantitative infrared surface heating measurements. This paper reviews both types of measurements. OCIS codes: (120.1740) Combustion diagnostics; (300.2530) Fluorescence, laser-induced; (110.3080) Infrared imaging.

Planar Laser-Induced Fluorescence (PLIF)↗

Transport delays associated with NASA Langley Flight Simulation Facility

This paper describes the transport delays associated with flight simulation programs currently operating at the NASA Langley Research Center (LaRC). Formulas are presented for calculating a rough estimate of the transport delay for a particular simulation. Various simulation programs that used the Flight Simulation Facility at LaRC, during the period of October 1993 to March 1994, were tested to determine the transport delays associated with the simulation program and any associated hardware. Several simulators were tested, including the Differential Maneuvering Simulator (DMS), the Visual Motion Simulator (VMS), and the Transport System Research Vehicle (TSRV).

Smith, R. Marshall↗

Pitch-Axis Aerodynamic Parameter Identification for NASA's F-15B

As part of NASA s Intelligent Flight Control Systems program, parameter identification experiments were carried out with NASA Dryden s F-15B TN 837 aircraft. The canard control surfaces, whose movement is highly correlated with aircraft angle of attack, and the aircraft s aerodynamic instability in the pitch axis contribute to making parameter identification challenging. The equation-error method of analysis is applied to several longitudinal parameter identification maneuvers and a new approach for compensating for flight-data signal time lags is developed, which improves the accuracy and consistency of the results.

Woodruff, Stephen L.↗

NASA's participation in the AVE-SESAME '79 program

NASA's Marshall Space Flight Center participated with its AVE (Atmospheric Variability Experiment) in a large interagency mesoscale and severe storms experiment identified herein as AVE-SESAME '79 (Atmospheric Variability Experiment-Severe Environmental Storms and Mesoscale Experiment 1979). A primary objective of NASA was to support an effort to acquire carefully edited sets of rawinsonde data during selected severe weather events for use in correlative and diagnostic studies with satellite and radar data obtained at approximately the same times. Data were acquired during six individual 24-h experiments on both the regional and storm scales over a network in the central United States that utilized approximately 20 supplemental rawinsonde sites meshed among 23 standard National Weather Service sites. Included among the six experiments are data obtained between 1200 GMT on April 10 and 1200 GMT on April 11, encompassing the formation and development period for the tornado-producing systems that devastated Wichita Falls, Texas, and other sections of Oklahoma and Texas. The other dates for which data sets are available are April 19-20 and 25-26, May 9-10 and 20-21, and June 7-8, 1979.

Hill, K.↗

NASA's Office of Aeronautics and Exploration Technology space power flight projects

NASA created a program called In-STEP (in-space technology experiments program) to give the aerospace community an opportunity to validate advanced technologies in space. In-STEP has funded feasibility studies for the following experiments in the power technology arena: a microsphere insulation investigation, a utilized regenerative fuel cell experiment, an inflatable solar collector experiment, a moving belt radiator experiment, and a liquid drop radiator experiment. The following experiments are currently in the experiment definition phase: an integrated two-phase thermal experiment, an electrolysis performance experiment, and a sodium sulfur battery experiment. Three In-STEP experiments are entering the hardware fabrication phase: thermal energy storage technology, solar array module plasma interaction, and heat pipe performance experiments. Each of these experiments is described, with an emphasis on the benefits of technology validation.

Chmielewski, Art B.↗

Controlled ecological life support systems (CELSS) flight experimentation

The NASA CELSS program has the goal of developing life support systems for humans in space based on the use of higher plants. The program has supported research at universities with a primary focus of increasing the productivity of candidate crops plants. To understand the effects of the space environment on plant productivity, the CELSS Test Facility (CTF) has been conceived as an instrument that will permit the evaluation of plant productivity on Space Station Freedom. The CTF will maintain specific environmental conditions and collect data on gas exchange rates and biomass accumulation over the growth period of several crop plants grown sequentially from seed to harvest. The science requirements for the CTF will be described, as will current design concepts and specific technology requirements for operation in micro-gravity.

Kliss, M.↗

Hot Structure Control Surface Progress for X-37 Technology Development Program

The NASA Marshall Space Flight Center (MSFC) has been leading the development of technologies that will enable the development, fabrication, and flight of the automated X-37 Orbital Vehicle (OV). With the Administration s recent announcement of the Vision for Space Exploration, NASA placed the X-37 OV design on hold while developing detailed requirements for a Crew Exploration Vehicle, but has continued funding the development of high-risk, critical technologies for potential future space exploration vehicle applications. Hot Structure Control Surfaces (HSCS) technology development is one of the high-priority areas being funded at this time. The goal of HSCS research is to mitigate risk by qualifying the lightest possible components that meet the stringent X-37 OV weight and performance requirements, including Shuttle-type reen- try environments with peak temperatures of 2800 OF. The small size of the X-37 OV (25.7-feet long and 14.9-foot wingspan) drives the need for advanced HSCS because the vehicle's two primary aerodynamic surfaces, the flaperons and ruddervators, have thicknesses ranging from approximately 5 in. down to 1 in. Traditional metallic or polymer-matrix composites covered with tile or blanket thermal protection system (TPS) materials cannot be used as there is insufficient volume to fabricate such multi-component structures. Therefore, carbon-carbon (C-C) and carbodsilicon-carbide (C-SiC) composite HSCS structures are being developed in parallel by two teams supporting the X-37 prime contractor (The Boeing Company). The Science Applications International Coy. (SAIC) and Carbon-Carbon Advanced Technologies, Inc. (C-CAT) team is developing the C-C HSCS, while the General Electric Energy Power Systems Composites (GE-PSC) and Materials Research and Design (MRD) team is developing the C-SiC HSCS. These two teams were selected to reduce the high level of risk associated with developing advanced control surface components. They have continued HSCS development work as part of the X-37 critical technology development contract. The SAIC/C-CAT team is using Advanced Carbon-Carbon (ACC) because its fabrication is very similar to the process used for Space Shuttle Reinforced Carbon-Carbon fabrication, including the Sic-based pack cementation conversion coating systems using with both materials. ACC was selected over RCC because it has much higher tension and compressions strengths, and because T-300 fiber is readily available, whereas RCC rayon fiber is no longer manufactured. The GE-PSC/MRD team is using a T-300 fiber-reinforced Sic matrix composite material densified by chemical vapor infiltration. The C-Sic material has an Sic-based environmental barrier coating. Major accomplishments have been made over the past year by both HSCS teams. C-C and C- SiC flaperon subcomponents, which are truncated full-scale versions of flight hardware, have been fabricated and are undergoing testing at the NASA Dryden Flight Research Center, NASA Langley Research Center, and U.S. Air Force Research Laboratory. By the end of 2004, ruddervator subcomponents also will be delivered and tested. As NASA moves forward in realizing the Vision for Space Exploration, it will continue to invest in advanced research and development aimed at making new generations of spacecraft safer, more reliable, and more affordable. The X-37 HSCS effort ultimately will benefit the Agency's vision and mission.

Valentine, P. G.↗

Microtechnology in Space: NASA's Lab-on-a-Chip Applications Development Program

NASA's Marshall Space Flight Center (MSFC) Lab on a Chip Application Development LOCAD) team has worked with microfluidic technology for the past few years in an effort to support NASA's Mission. In that time, such microfluidic based Lab-on-a-Chip (LOC) systems have become common technology in clinical and diagnostic laboratories. The approach is most attractive due to its highly miniaturized platform and ability to perform reagent handling (i-e., dilution, mixing, separation) and diagnostics for multiple reactions in an integrated fashion. LOCAD, along with Caliper Life Sciences has successfully developed the first LOC device for macromolecular crystallization using a workstation acquired specifically for designing custom chips, the Caliper 42. LOCAD uses this, along with a novel MSFC-designed and built workstation for microfluidic development. The team has a cadre of LOC devices that can be used to perform initial feasibility testing to determine the efficacy of the LOC approach for a specific application. Once applicability has been established, the LOCAD team, along with the Army's Aviation and Missile Command microfabrication facility, can then begin to custom design and fabricate a device per the user's specifications. This presentation will highlight the LOCAD team's proven and unique expertise that has been utilized to provide end to end capabilities associated with applying microfluidics for applications that include robotic life detection instrumentation, crew health monitoring and microbial and environmental monitoring for human Exploration.

Monaco, Lisa↗

Advanced Flight Computing Technologies for Validation by NASA's New Millennium Program

The New Millennium Program (NMP) consists of a series of deep-space and earth-orbiting missions that are technology-driven, in contrast to the more traditional science-driven space exploration missions of the past. These flights are designed to validate technologies that will enable a new era of low-cost highly miniaturized and highly capable spaceborne applications in the new millennium.

New↗

Flight characteristics of a manned, low-speed, controlled deep stall vehicle

A successful manned, low speed, controlled deep stall flight research program was conducted at NASA Ames Research Center's Dryden Flight Research Facility. Piloting techniques were established that enabled the pilot to attain and stabilize on an angle of attack in the 30 deg to 72 deg range. A flight determined aerodynamic data base was established for angles of attack as high as 72 deg. Poor lateral directional flying qualities were encountered at angles of attack above 60 deg. Insight into the high angle of attack lateral directional dynamics was gained through a basic root locus analysis.

Sim, A. G.↗

Air data position-error calibration using state reconstruction techniques

During the highly maneuverable aircraft technology (HiMAT) flight test program recently completed at NASA Ames Research Center's Dryden Flight Research Facility, numerous problems were experienced in airspeed calibration. This necessitated the use of state reconstruction techniques to arrive at a position-error calibration. For the HiMAT aircraft, most of the calibration effort was expended on flights in which the air data pressure transducers were not performing accurately. Following discovery of this problem, the air data transducers of both aircraft were wrapped in heater blankets to correct the problem. Additional calibration flights were performed, and from the resulting data a satisfactory position-error calibration was obtained. This calibration and data obtained before installation of the heater blankets were used to develop an alternate calibration method. The alternate approach took advantage of high-quality inertial data that was readily available. A linearized Kalman filter (LKF) was used to reconstruct the aircraft's wind-relative trajectory; the trajectory was then used to separate transducer measurement errors from the aircraft position error. This calibration method is accurate and inexpensive. The LKF technique has an inherent advantage of requiring that no flight maneuvers be specially designed for airspeed calibrations. It is of particular use when the measurements of the wind-relative quantities are suspected to have transducer-related errors.

Whitmore, S. A.↗

Flight characteristics of a manned, low-speed, controlled deep stall vehicle

A successful manned, low-speed, controlled deep stall flight research program was conducted at NASA Ames Research Center's Dryden Flight Research Facility. Piloting techniques were established that enabled the pilot to attain and stabilize on an angle of attack in the 30 to 72 deg range. A flight-determined aerodynamic data base was established for angles of attack as high as 72 deg. Poor lateral-directional flying qualities were encountered at angles of attack above 60 deg. Insight into the high angle-of-attack, lateral-directional dynamics was gained through a basic root-locus analysis.

Sim, A. G.↗