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At least 451 records · Page 25

Locomotion in Lymphocytes is Altered by Differential PKC Isoform Expression

Lymphocyte locomotion is critical for proper elicitation of the immune response. Locomotion of immune cells via the interstitium is essential for optimal immune function during wound healing, inflammation and infection. There are conditions which alter lymphocyte locomotion and one of them is spaceflight. Lymphocyte locomotion is severely inhibited in true spaceflight (true microgravity) and in rotating wall vessel culture (modeled microgravity). When lymphocytes are activated prior to culture in modeled microgravity, locomotion is not inhibited and the levels are comparable to those of static cultured lymphocytes. When a phorbol ester (PMA) is used in modeled microgravity, lymphocyte locomotion is restored by 87%. This occurs regardless if PMA is added after culture in the rotating wall vessel or during culture. Inhibition of DNA synthesis also does not alter restoration of lymphocyte locomotion by PMA. PMA is a direct activator of (protein kinase C) PKC . When a calcium ionophore, ionomycin is used it does not possess any restorative properties towards locomotion either alone or collectively with PMA. Since PMA brings about restoration without help from calcium ionophores (ionomycin), it is infer-red that calcium independent PKC isoforms are involved. Changes were perceived in the protein levels of PKC 6 where levels of the protein were downregulated at 24,72 and 96 hours in untreated rotated cultures (modeled microgravity) compared to untreated static (1g) cultures. At 48 hours there is an increase in the levels of PKC & in the same experimental set up. Studies on transcriptional and translational patterns of calcium independent isoforms of PKC such as 8 and E are presented in this study.

Sundaresan, A.↗

A theory for turbulent curved wall jets

A simple theoretical model is proposed to describe the flow of a turbulent wall jet along a curved surface into a quiescent atmosphere. An integral method is used to solve the momentum equation and identifies three contributions to the spreading rate of the wall jet: (1) turbulent diffusion in the wall jet; (2) wall curvature; and (3) rate of change of wall curvature. Closed from approximate solutions are found for the case of a plane wall, a circular cylinder, and a logarithmic spiral surface. Comparison with experimental data for these three cases is made showing good agreement.

Roberts, Leonard↗

Thermal Desktop Modeling of 2016 CRYOTE-2 Tank Chill and Fill Testing

The storing and transfer of cryogenic propellants is an enabling technology for NASA and industry as civilization moves to expand future missions into low Earth orbit and beyond. Several ground propellant transfer tests have been conducted in past decades examining various tank chilldown and fill methods. Creating accurate models using these historical datasets is a vital step toward developing appropriate modeling tools to form pre-test predictions for subsequent ground and flight propellant transfers. This paper presents model validation of Thermal Desktop using data from the 2016 CRYOTE-2 liquid nitrogen transfer experiments whose purpose was to demonstrate the chill and fill process in a spherical receiver tank. Tank pressure, fill level, and wall temperature were all modeled and compared with 8 test cases using two modeling methods, Mass Controlled, and Pressure Controlled. This test series is the hardest Thermal Desktop tank chill and fill validation case to-date, yet the model was able to accurately predict each of these metrics for the 2016 tests within 28%, 10%, 20% respectively, for pressure, fill level, and wall temperature using the Mass Controlled model, and 29%, 79%, and 12%, respectively for the Pressure Controlled model.

Cryogenic Tank Chilldown↗

Elliptic Relaxation of a Tensor Representation for the Redistribution Terms in a Reynolds Stress Turbulence Model

A formulation to include the effects of wall proximity in a second-moment closure model that utilizes a tensor representation for the redistribution terms in the Reynolds stress equations is presented. The wall-proximity effects are modeled through an elliptic relaxation process of the tensor expansion coefficients that properly accounts for both correlation length and time scales as the wall is approached. Direct numerical simulation data and Reynolds stress solutions using a full differential approach are compared for the case of fully developed channel flow.

Carlson, J. R.↗

Development of an improved model for runback water on aircraft surfaces

A computer simulation for 'running wet' and evaporative aircraft anti-icing systems is developed. The model is based on the analysis of the liquid water film which forms in the regions of direct impingement and, then, breaks up near the impingement limits into rivulets. The wetness factor distribution resulting from the film breakup and the rivulet configuration on the surface are predicted using a stability analysis theory and the laws of mass energy conservation. The solid structure is modeled as a multiple layer wall. The anti-icing system modeled is of the thermal type utilizing hot air and/or electrical heating elements embedded within the wall layers. Experimental observations revealing some of the basic physics of the water flow on the surface are presented. Detailed qualitative documentation of the tests are given. Several numerical examples are considered, and the effect of some of the involved parameters on the system performance are investigated.

Al-Khalil, Kamel M.↗

Measurements and Computations of the Turbulent Corner Flow on the NASA Juncture-Flow Model with a Symmetric Wing

The NASA Juncture Flow experiment is designed to acquire high-quality flowfield data deep in the corner of a wing-fuselage junction specifically for the purpose of computational fluid dynamics (CFD) validation and turbulence model improvement. This paper presents and discusses the results of a recent experiment with the juncture-flow model in the NASA Langley 14- by 22-Foot Subsonic Tunnel. The main objective of the test was to expand the existing juncture-flow dataset with a symmetric wing case that displays fully attached, incipient separation, and separated flow in the corner of the wing-fuselage junction, depending on the model angle of incidence. Laser Doppler velocimetry (LDV) measurements were made at three model angles of incidence (0 deg: fully attached, 1 deg: incipient separation, and 5 deg: separated flow) and for each one, mean-flow and Reynolds-stress data were obtained on the fuselage and at several streamwise locations along the corner of the wing-fuselage junction. Supporting measurements were made during the test campaign and included model and tunnel wall static pressures, tunnel wall and ceiling boundary-layer rake data, oil-flow visualizations, and laser-based measurements of the as-built model geometry and model position in the test section. Comparisons between the experimental data on the test article and Reynolds-averaged Navier-Stokes CFD results are presented and discussed.

Juncture Flow↗

Measurements and Computations of the Turbulent Corner Flow on the NASA Juncture-Flow Model with a Symmetric Wing

The NASA Juncture Flow experiment is designed to acquire high-quality flowfield data deep in the corner of a wing-fuselage junction specifically for the purpose of computational fluid dynamics (CFD) validation and turbulence model improvement. This paper will present and discuss the results of a recent experiment with the juncture-flow model in the NASA Langley 14- by 22-Foot Subsonic Tunnel. The main objective of that test was to expand the existing juncture-flow dataset with a symmetric wing case that displays fully attached, incipient separation, and separated flow in the corner of the wing-fuselage junction, depending on the model pitch angle. Laser Doppler velocimetry (LDV) measurements were made at three model pitch angles (0 deg: fully attached, 1 deg: incipient separation, and 5 deg: separated flow) and for each one, mean-flow and Reynolds-stress data was obtained on the fuselage and at several streamwise locations along the corner of the wing-fuselage junction. Supporting measurements were made during the test campaign and included model and tunnel wall static pressures, tunnel wall and ceiling boundary-layer rake data, oil-flow visualizations, and laser-based measurements of the as-built model geometry and model position in the test section. Comparisons between the experimental data and Reynolds averaged Navier-Stokes CFD results will also be presented and discussed.

Juncture Flow↗

Measurements and Computations of the Turbulent Corner Flow on the NASA Juncture-Flow Model with a Symmetric Wing

The NASA Juncture Flow experiment is designed to acquire high-quality flowfield data deep in the corner of a wing-fuselage junction specifically for the purpose of computational fluid dynamics (CFD) validation and turbulence model improvement. This paper will present and discuss the results of a recent experiment with the juncture-flow model in the NASA Langley 14- by 22-Foot Subsonic Tunnel. The main objective of that test was to expand the existing juncture-flow dataset with a symmetric wing case that displays fully attached, incipient separation, and separated flow in the corner of the wing-fuselage junction, depending on the model pitch angle. Laser Doppler velocimetry (LDV) measurements were made at three model pitch angles (0 deg: fully attached, 1 deg: incipient separation, and 5 deg: separated flow) and for each one, mean-flow and Reynolds-stress data was obtained on the fuselage and at several streamwise locations along the corner of the wing-fuselage junction. Supporting measurements were made during the test campaign and included model and tunnel wall static pressures, tunnel wall and ceiling boundary-layer rake data, oil-flow visualizations, and laser-based measurements of the as-built model geometry and model position in the test section. Comparisons between the experimental data and Reynolds averaged Navier-Stokes CFD results will also be presented and discussed.

Juncture Flow↗

Effect of blockage ratio on drag and pressure distributions for bodies of revolution at transonic speeds

Experimental data were obtained in two wind tunnels for 13 models over a Mach number range from 0.70 to 1.02. Effects of increasing test-section blockage ratio in the transonic region near a Mach number of 1.0 included change in the shape of the drag curves, premature drag creep, delayed drag divergence, and a positive increment of pressures on the model afterbodies. Effects of wall interference were apparent in the data even for a change in blockage ratio from a very low 0.000343 to an even lower 0.000170. Therefore, models having values of blockage ratio of 0.0003 - an order of magnitude below the previously considered safe value of 0.0050 - had significant errors in the drag-coefficient values obtained at speeds near a Mach number of 1.0. Furthermore, the flow relief afforded by slots or perforations in test-section walls - designed according to previously accepted criteria for interference-free subsonic flow - does not appear to be sufficient to avoid significant interference of the walls with the model flow field for Mach numbers very close to 1.0.

Couch, L. M.↗

Spacecraft Internal Acoustic Environment Modeling

Acoustic modeling can be used to identify key noise sources, determine/analyze sub-allocated requirements, keep track of the accumulation of minor noise sources, and to predict vehicle noise levels at various stages in vehicle development, first with estimates of noise sources, later with experimental data. This paper describes the implementation of acoustic modeling for design purposes by incrementally increasing model fidelity and validating the accuracy of the model while predicting the noise of sources under various conditions. During FY 07, a simple-geometry Statistical Energy Analysis (SEA) model was developed and validated using a physical mockup and acoustic measurements. A process for modeling the effects of absorptive wall treatments and the resulting reverberation environment were developed. During FY 08, a model with more complex and representative geometry of the Orion Crew Module (CM) interior was built, and noise predictions based on input noise sources were made. A corresponding physical mockup was also built. Measurements were made inside this mockup, and comparisons were made with the model and showed excellent agreement. During FY 09, the fidelity of the mockup and corresponding model were increased incrementally by including a simple ventilation system. The airborne noise contribution of the fans was measured using a sound intensity technique, since the sound power levels were not known beforehand. This is opposed to earlier studies where Reference Sound Sources (RSS) with known sound power level were used. Comparisons of the modeling result with the measurements in the mockup showed excellent results. During FY 10, the fidelity of the mockup and the model were further increased by including an ECLSS (Environmental Control and Life Support System) wall, associated closeout panels, and the gap between ECLSS wall and mockup wall. The effect of sealing the gap and adding sound absorptive treatment to ECLSS wall were also modeled and validated.

Chu, Shao-Sheng R.↗

Turbulence closure modeling near rigid boundaries

The near-wall region plays an essential role in turbulent boundary layers: it is a region of high shear; the peak rate of production and peak intensity of turbulence occurs there; and the peak rate of dissipation occurs right at the wall. Nevertheless, this region has received less attention from modelers than have more nearly homogeneous flows. One reason for this is that when the boundary layer is near equilibrium, experimental data can be used to prescribe the flow in the wall layer. Another reason is that most turbulence models are developed under assumptions of near homogeneity. This is a poor approximation in the wall region. A single-point moment closure model for the strongly non-homogeneous A turbulent flow near a rigid boundary is developed.

Durbin, Paul A.↗

Progress Towards Fuselage Drag Reduction via Active Flow Control: A Combined CFD and Experimental Effort

A combined computational and experimental effort has been undertaken to study fuselage drag reduction on a generic, non-proprietary rotorcraft fuselage by the application of active ow control. Fuselage drag reduction is an area of research interest to both the United States and France and this area is being worked collaboratively as a task under the United States/France Memorandum of Agreement on Helicopter Aeromechanics. In the first half of this task, emphasis is placed on the US generic fuselage, the ROBIN-mod7, with the experimental work being conducted on the US side and complementary US and French CFD analysis of the baseline and controlled cases. Fuselage simulations were made using Reynolds-averaged Navier-Stokes ow solvers and with multiple turbulence models. Comparisons were made to experimental data for numerical simulations of the isolated fuselage and for the fuselage as installed in the tunnel, which includes modeling of the tunnel contraction, walls, and support fairing. The numerical simulations show that comparisons to the experimental data are in good agreement when the tunnel and model support are included. The isolated fuselage simulations compare well to each other, however, there is a positive shift in the centerline pressure when compared to the experiment. The computed flow separation locations on the rear ramp region had only slight differences with and without the tunnel walls and model support. For the simulations, the flow control slots were placed at several locations around the flow separation lines as a series of eight slots that formed a nearly continuous U-shape. Results from the numerical simulations resulted in an estimated 35% fuselage drag reduction from a steady blowing flow control configuration and a 26% drag reduction for unsteady zero-net-mass flow control configuration. Simulations with steady blowing show a delayed flow separation at the rear ramp of the fuselage that increases the surface pressure acting on the ramp, thus decreasing the overall fuselage pressure drag.

Schaeffler, Norman W.↗

Space Shuttle main engine nozzle-steerhorn dynamics

On two occasions during the Space Shuttle main engine development, the LH2 feedline (called the steerhorn, because of its shape) failed during the cutoff transient. A dynamic test was undertaken, and an analytical model was developed and correlated to the dynamic test. Detailed models of the tube bundle were required to obtain the equivalent shell coefficients. All-shell models of the nozzle wall were found better than beam-shell models. The most difficult part of the structure to simulate was the felt-metal pad between the feedline and its mount, which introduced nonlinear stiffness and damping and led to the use of separate low amplitude and high amplitude models. The total structure was found to have 400 modes in the frequency range of interest, 0 to 500 Hz. Good test analysis correlation was obtained and a modified feedline configuration was found to demonstrate a 40% reduction of response stress from the original configuration.

Kiefling, L.↗

The present state and future direction of second order closure models for compressible flows

The topics are presented in viewgraph form and include: (1) Reynolds stress closure models; (2) Favre averages and governing equations; (3) the model for the deviatoric part of the pressure-strain rate correlation; (4) the SSG pressure-strain correlation model; (5) a compressible turbulent dissipation rate model; (6) variable viscosity effects; (7) near-wall stiffness problems; (8) models of the Reynolds mass and heat flux; and (9) a numerical solution of the compressible turbulent transport equation.

Gatski, Thomas B.↗

Heat transfer in rotating serpentine passages with trips skewed to the flow

Experiments were conducted to determine the effects of buoyancy and Coriolis forces on heat transfer in turbine blade internal coolant passages. The experiments were conducted with a large scale, multi-pass, heat transfer model with both radially inward and outward flow. Trip strips, skewed at 45 deg to the flow direction, were machined on the leading and trailing surfaces of the radial coolant passages. An analysis of the governing flow equations showed that four parameters influence the heat transfer in rotating passages: coolant-to-wall temperature, rotation number, Reynolds number, and radius-to-passage hydraulic diameter ratio. The first three of these four parameters were varied over ranges which are typical of advanced gas turbine engine operating conditions. Results were correlated and compared to previous results from similar stationary and rotating models with smooth walls and with trip strips normal to the flow direction. The heat transfer coefficients on surfaces, where the heat transfer decreased with rotation and buoyancy, decreased to as low as 40 percent of the value without rotation. However, the maximum values of the heat transfer coefficients with high rotation were only slightly above the highest levels previously obtained with the smooth wall models. It was concluded that (1) both Coriolis and buoyancy effects must be considered in turbine blade cooling designs with trip strips, (2) the effects of rotation are markedly different depending upon the flow direction, and (3) the heat transfer with skewed trip strips is less sensitive to buoyancy than the heat transfer in models with either smooth or normal trips. Therefore, skewed trip strips rather than normal trip strips are recommended and geometry-specific tests are required for accurate design information.

Johnson, B. V.↗

Discontinuous Galerkin Methods for Turbulence Simulation

A discontinuous Galerkin (DG) method is formulated, implemented, and tested for simulation of compressible turbulent flows. The method is applied to turbulent channel flow at low Reynolds number, where it is found to successfully predict low-order statistics with fewer degrees of freedom than traditional numerical methods. This reduction is achieved by utilizing local hp-refinement such that the computational grid is refined simultaneously in all three spatial coordinates with decreasing distance from the wall. Another advantage of DG is that Dirichlet boundary conditions can be enforced weakly through integrals of the numerical fluxes. Both for a model advection-diffusion problem and for turbulent channel flow, weak enforcement of wall boundaries is found to improve results at low resolution. Such weak boundary conditions may play a pivotal role in wall modeling for large-eddy simulation.

Collis, S. Scott↗

Efficient Parametric Uncertainty Analysis of an Earth Entry Vehicle Concept Using Least Angle Regression

The objective of this work was to outline and apply an efficient and accurate parametric un-certainty propagation approach to the analysis of convective heating on an Earth entry vehicle concept. The described approach was based on Least Angle Regression used to solve a sparse and underdetermined linear system in the point-collocation non-intrusive polynomial chaos surrogate method. This approach involved an iterative process to computing the non-zero terms of the underlying polynomial chaos model using only enough samples to converge uncertainty interval predictions and Sobol index values based global nonlinear sensitivity estimates. The Earth entry vehicle was analyzed at three points along a representative trajectory for a Mars return mission. 329 sources of uncertainty were identified in the computational fluid dynamics model used to predict the forebody convective heating. These included uncertainty in flow field chemical rates, collision integrals, heats of formation, surface finite rate char model reaction rates, wall roughness height, and the turbulent Schmidt number. Results from this study showed that convective heating uncertainty as high as 50% of the nominal was predicted with only about 50 evaluations of the computational model. This was far fewer than would be required for a sampling-based approach or a full basis polynomial chaos model, which would have required over 50,000 samples. Additionally, results showed that over 90% of the total convective heating uncertainty was due to uncertainty in the N2catalytic rate on the surface, while the remainder of the uncertainty was attributed to the turbulent Schmidt number and the wall roughness uncertainties.

Thomas K West IV↗

Heat transfer in rotating serpentine passages with smooth walls

Experiments were conducted to determine the effects of buoyancy and Coriolis forces on heat transfer in turbine blade internal coolant passages. The experiments were conducted with a large scale, multi-pass, smooth-wall heat transfer model with both radially inward and outward flow. An analysis of the governing flow equations showed that four parameters influence the heat transfer in rotating passages (coolant-to-wall temperature ratio, Rossby number, Reynolds number and radius-to-passage hydraulic diameter ratio). These four parameters were varied over ranges which are typical of advanced gas turbine engine operating conditions. It was found that both Coriolis and buoyancy effects must be considered in turbine blade cooling designs and that the effect of rotation on the heat transfer coefficients was markedly different depending on the flow direction. Local heat transfer coefficients were found to decrease by as much as 60 percent and increase by 250 percent from no rotation levels. Comparisons with a pioneering stationary vertical tube buoyancy experiment showed reasonably good agreement. Correlation of the data is achieved employing dimensionless parameters derived from the governing flow equations.

Wagner, J. H.↗