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Optimal preparation of the ECC ozonesonde

The ECC background current was identified as the removal of residual tri-iodide (iodine) as the cell approaches equilibrium. The altitude dependence of this source of the background current is expected to be only slowly changed in the troposphere with a more rapid decrease in the stratosphere. Oxygen does not play a role in the background current except in the unlikely situation where the electrodes have had all forms of iodine removed from them and the electrodes have not re-equilibrated with the sonde solutions before use. A solution mass transport parameter in the ECC was identified and its altitude dependence determined. The mass transport of tri-iodide dominates in the chemical transduction of ozone to electrical signal. The effect of the mass transport on the ECC background current is predicted. An electrochemical model of the ECC has been developed to predict the response of the ECC to various ozone vertical profiles. The model corresponds very closely to the performance of the ECC in the laboratory. Based on this model, an ECC with no background current is predicted to give total ozone values within 1% of the correct value, although the vertical profile may be in error by as much as + or - 15%.

Thornton, D. C.↗

Curved Duct Noise Prediction Using the Fast Scattering Code

Results of a study to validate the Fast Scattering Code (FSC) as a duct noise predictor, including the effects of curvature, finite impedance on the walls, and uniform background flow, are presented in this paper. Infinite duct theory was used to generate the modal content of the sound propagating within the duct. Liner effects were incorporated via a sound absorbing boundary condition on the scattering surfaces. Simulations for a rectangular duct of constant cross-sectional area have been compared to analytical solutions and experimental data. Comparisons with analytical results indicate that the code can properly calculate a given dominant mode for hardwall surfaces. Simulated acoustic behavior in the presence of lined walls (using hardwall duct modes as incident sound) is consistent with expected trends. Duct curvature was found to enhance weaker modes and reduce pressure amplitude. Agreement between simulated and experimental results for a straight duct with hard walls (no flow) was excellent.

Dunn, M. H.↗

Specification and Design of the SBRC-190: A Cryogenic Multiplexer for Far Infrared Photoconductor Detectors

Arrays of far-infrared photoconductor detectors operate at a few degrees Kelvin and require electronic amplifiers in close proximity. For the electronics, a cryogenic multiplexer is ideal to avoid the large number of wires associated with individual amplifiers for each pixel, and to avoid adverse effects of thermal and radiative heat loads from the circuitry. For low background applications, the 32 channel CRC 696 CMOS device was previously developed for SIRTF, the cryogenic Space Infrared Telescope Facility. For higher background applications, we have developed a similar circuit, featuring several modifications: (a) an AC coupled, capacitive feedback transimpedence unit cell, to minimize input offset effects, thereby enabling low detector biases, (b) selectable feedback capacitors to enable operation over a wide range of backgrounds, and (c) clamp and sample & hold output circuits to improve sampling efficiency, which is a concern at the high readout rates required. We describe the requirements for and design of the new device.

Erickson, E. F.↗

Phase Inversion: Inferring Solar Subphotospheric Flow and Other Asphericity from the Distortion of Acoustic Waves

A method is proposed for analyzing an almost monochromatic train of waves propagating in a single direction in an inhomogeneous medium that is not otherwise changing in time. An effective phase is defined in terms of the Hilbert transform of the wave function, which is related, via the JWKB approximation, to the spatial variation of the background state against which the wave is propagating. The contaminating effect of interference between the truly monochromatic components of the train is eliminated using its propagation properties. Measurement errors, provided they are uncorrelated, are manifest as rapidly varying noise; although that noise can dominate the raw phase-processed signal, it can largely be removed by low-pass filtering. The intended purpose of the analysis is to determine the distortion of solar oscillations induced by horizontal structural variation and material flow. It should be possible to apply the method directly to sectoral modes. The horizontal phase distortion provides a measure of longitudinally averaged properties of the Sun in the vicinity of the equator, averaged also in radius down to the depth to which the modes penetrate. By combining such averages from different modes, the two-dimensional variation can be inferred by standard inversion techniques. After taking due account of horizontal refraction, it should be possible to apply the technique also to locally sectoral modes that propagate obliquely to the equator and thereby build a network of lateral averages at each radius, from which the full three-dimensional structure of the Sun can, in principle, be determined as an inverse Radon transform.

Gough, Douglas↗

The effects of correlated noise in phased-array observations of radio sources

Arrays of radio telescopes are now routinely used to provide increased signal-to-noise when observing faint point sources. However, calculation of the achievable sensitivity is complicated if there are sources in the field of view other than the target source. These additional sources not only increase the system temperatures of the individual antennas, but may also contribute significant 'correlated noise' to the effective system temperature of the array. This problem has been of particular interest in the context of tracking spacecraft in the vicinity of radio-bright planets (e.g., Galileo at Jupiter), but it has broader astronomical relevance as well. This paper presents a general formulation of the problem, for the case of a point-like target source in the presence of an additional radio source of arbitrary brightness distribution. We re-derive the well known result that, in the absence of any background sources, a phased array of N indentical antennas is a factor of N more sensitive than a single antenna. We also show that an unphased array of N identical antennas is, on average, no more sensitive than a single antenna if the signals from the individual antennas are combined prior to detection. In the case where a background source is present we show that the effects of correlated noise are highly geometry dependent, and for some astronomical observations may cause significant fluctuations in the array's effective system temperature.

Dewey, Rachel J.↗

40 Eridani and the gravitational lens effect

Observations covering a period of 20 years show that the large proper motion (4.08 arcsec/yr) of the nearly triple system 40 Eridani-ABC will cause its brightest member, A, to pass within 3 arcsec of a faint background star. The originally hoped-for primary gravitational lens effect will therefore not take place although a minor secondary effect may occur near the time of closest approach on June 1, 1987.

Feibelman, Walter A.↗

Measurements of Siple transmitter signals on the DE 1 satellite - Wave normal direction and antenna effective length

A new experimental technique is developed to simultaneously measure the wave propagation direction and the effective length of a small (L value much smaller than wavelength) electric dipole antenna on a spin-stabilized satellite in the magnetosphere. The technique relies on the near simultaneous measurement of single components of the electric and magnetic fields of a coherent VLF signal injected into the medium from a ground-based source. The spin fading characteristics of the signal received by the electric dipole and the magnetic loop antenna permit the measurement of the wave normal direction assuming whistler-mode propagation. In-situ and remote measurements of the local cold plasma density are used to determine the refractive index. The wave electric field is then inferred from the wave magnetic field as measured on the loop antenna, the refractive index and the direction of propagation. Comparing this electric field with the measured voltage across the dipole antenna leads to the determination of the effective length of the receiving electric dipole. The technique is applied to data from the Dynamics Explorer 1 satellite observations of whistler mode signals injected into the magnetosphere from the Siple, Antarctica, VLF transmitter. In one case, with the measured background cold plasma density being 15 el/cu cm, the effective length of the 200 m-long electric dipole antenna is found to be 222 + or - 56 m, i.e., about twice the conventional value.

Sonwalker, V. S.↗

Limits to the radiative decay of the axion

An axion with a mass greater than 1 eV should be detectable through its decay into two photons. The astrophysical and cosmological limits which define a small window of allowed axion mass above 3 eV are discussed. A firm upper bound to the axion's mass of M(sub a) less than or equal to 8 eV is derived by considering the effect of decaying axions upon the diffuse extragalactic background radiation and the brightness of the night sky due to axions in the halo of the Milky Way galaxy. The intergalactic light of clusters of galaxies is shown to be an ideal place to search for an emission line arising from the radiative decay of axions. An unsuccessful search for this emission line in three clusters of galaxies is then detailed. Limits to the presence of any intracluster line emission are derived with the result that axions with masses between 3 and 8 eV are excluded by the data, effectively closing this window of axion mass, unless a severe cancellation of axionic decay amplitudes occurs. The intracluster flux limits are then used to constrain the amplitude of any such model dependence.

Ressell, M. Ted↗

Assessing the Effect of Spaceflight on the Propensity for Astronauts to Develop Disk Herniation

BACKGROUND: A previous study [1] reported that the instantaneous risk of developing a Herniated Nucleus Pulposus (HNP) was higher in astronauts who had flown at least one mission, as compared with those in the corps who had not yet flown. However, the study only analyzed time to HNP after the first mission (if any) and did not account for the possible effects of multiple missions. While many HNP's occurred well into astronauts' careers or in some cases years after retirement, the higher incidence of HNPs relatively soon after completion of space missions appears to indicate that spaceflight may lead to an increased risk of HNP. The purpose of this study was to support the Human System Risk Board assessment of back pain, evaluate the risk of injury due to dynamic loads, and update the previous dataset which contained events up to December 31, 2006. METHODS: Data was queried from the electronic medical record and provided by the Lifetime Surveillance of Astronaut Health. The data included all 330 United States astronauts from 1959 through February 2014. Cases were confirmed by Magnetic Resonance Imaging, Computerized Tomography, Myelography, operative findings, or through clinical confirmation with a neurologist or neurosurgeon. In this analysis, astronauts who had an HNP at selection into the corps or had an HNP diagnosis prior to their first flight were excluded. The statistical challenges in using the available data to separate effects of spaceflight from those associated with general astronaut training and lifestyle on propensity to develop HNPs are many. The primary outcome is reported date of first HNP (if any), which at best is only an approximation to the actual time of occurrence. To properly analyze this data with a survival analysis model, one must also know the "exposure" time - i.e. how long each astronaut has been at risk for developing an HNP. If an HNP is reported soon after a mission, is it mission caused or general? If the former, exposure time should be counted from the time of landing (assuming the risk of HNP occurring during a mission is zero). If the latter, exposure time should be counted from the time of selection; however we can't directly know which one to use. In our analysis we take both of these possibilities into account with a competing risks model, wherein two distinct stochastic processes are going on: TG = time to HNP (general) and TS = time to HNP (spaceflight). Under this type of model, whichever of these occurs first is what we observe; in other words we don't observe TG or TS, only min(TG, TS). Here, we parameterized the model in terms of separate Weibull hazard functions for each process and estimated all parameters using maximum likelihood. In addition, we allowed for a "cured fraction" - i.e. the possibility that some astronauts may never develop an HNP. RESULTS: Results will include a depiction of the competing hazard functions as well as a probability curve for the relative likelihood that an HNP reported at a given time after a mission is actually mission caused. Other factors, such as dwell time in microgravity and vehicle landing environment will be explored. An overall assessment as to whether spaceflight truly exacerbates HNP risk will be made.

Feiveson, A. H.↗

Effects of proton and gamma radiation on lymphocyte populations and acute response to antigen

BACKGROUND: The clinical use of proton radiation in the management of cancer, as well as benign disorders, is rapidly increasing. The major goal of this study was to compare the effects of proton and gamma (60Co) radiation on cell-mediated and humoral immunological parameters. MATERIALS AND METHODS: C57BL/6 mice were exposed to a single dose of 3 Gray (Gy) protons or gamma-rays and intraperitoneally injected 1 day later with sheep red blood cells (sRBC). On 4, 10, 15, and 29 days after exposure, subsets from each group were euthanised; nonirradiated controls (with and without sRBC injection) were included. Body and relative spleen weights, leukocyte counts, spontaneous blastogenesis, lymphocyte populations, and anti-sRBC titers were evaluated. RESULTS: The data showed significant depression (p < 0.05) in nearly all assays on days 4 and 10 after irradiation. B lymphocytes (CD19+) were the most radiosensitive, although reconstitution back to normal levels was observed by day 15. T cell (CD3+) and T helper cell (CD4+) recovery was evident by day 29, whereas the T cytotoxic cell (CD8+) count remained significantly below normal. Natural killer cells (NK1.1+) were relatively radioresistant. Anti-sRBC antibody production was slow and low titers were obtained after irradiation. No significant differences were noted between the two types of radiation. CONCLUSIONS: Taken together, the data show that whole-body irradiation with protons or gamma-rays, at the dose employed, results in marked, but transient, immunosuppression. However, at the time points of testing and with the assays used, little or no differences were found between the two forms of radiation.

NASA Discipline Radiation Health↗

Effects of ionizing radiation on cryogenic infrared detectors

The Diffuse Infrared Background Experiment (DIRBE) is one of three experiments to be carried aboard the Cosmic Background Explorer (COBE) satellite scheduled to be launched by NASA on a Delta rocket in 1989. The DIRBE is a cryogenic absolute photometer operating in a liquid helium dewar at 1.5 K. Photometric stability is a principal requirement for achieving the scientific objectives of this experiment. The Infrared Astronomy Satellite (IRAS), launched in 1983, which used detectors similar to those in DIRBE, revealed substantial changes in detector responsivity following exposure to ionizing radiation encountered on passage through the South Atlantic Anomaly (SAA). Since the COBE will use the same 900 Km sun-synchronous orbit as IRAS, ionizing radiation-induced performance changes in the detectors were a major concern. Here, ionizing radiation tests carried out on all the DIRBE photodetectors are reported. Responsivity changes following exposure to gamma rays, protons, and alpha particle are discussed. The detector performance was monitored following a simulated entire mission life dose. In addition, the response of the detectors to individual particle interactions was measured. The InSb photovoltaic detectors and the Blocked Impurity Band (BIB) detectors revealed no significant change in responsivity following radiation exposure. The Ge:Ga detectors show large effects which were greatly reduced by proper thermal annealing.

Moseley, S. H.↗

Effects of Spaceflight Relevant Carbon Dioxide Levels on Pathogenesis Related Microbial Characteristics

Background - Spaceflight can alter microbial pathogenesis - Microgravity (Nickerson et al. 2000 Infect Immun 68(6):3147-52; Crabbe 2011 Appl Environ Mirobiol 77(4):1221-30; Gilbert 2020 NPJ Micrograv 6:4) - Radiation (Dornmayr-Pfaffenhuemer 2011 Astrobiol 11(3):199-205; Romsdahl 2020 Front Microbiol 11:931; Perrone 2020 Microorganisms 8(10):1496) - Elevated CO2 (0.4%, compared to earth at 0.04%) - The effect of slightly elevated CO2 concentrations on microbial pathogenesis has not been studied.

carbon dioxide↗

Effects of hypergravity on ovarian-hypophyseal function in antepartum and postpartum rats

BACKGROUND: Rats exposed to microgravity during the post-implantation phase of pregnancy had minimal alterations in ovarian and hypophyseal parameters during the antepartum and postpartum periods. In the current study, a similar parallel experimental design was employed to ascertain the effects of hypergravity on ovarian and hypophyseal function. HYPOTHESIS: We hypothesized that hypergravity exposure during the post-implantation stage of pregnancy would not alter antepartum and postpartum ovarian and hypophyseal function. METHODS: Pregnant rats were assigned to hypergravity (1.5 G, 1.75 G, or 2.0 G), rotational control, or stationary control groups (n = 10 each group) beginning on gestation day 11 and ending on day 20. Hypophyseal and ovarian analyses were conducted on 5 of the animals from each group at day 20. The remaining animals in each group were allowed to go to term and the same analyses were conducted 3 h postpartum. RESULTS: Hypergravity at all levels decreased the percent body mass gain from gestation day 11 to 20 (p < 0.05); however, the wet weight of the pituitaries and ovaries was not changed. There was no effect of hypergravity on the number of healthy or atretic antral follicles of any size at gestation day 20 or postpartum. The number of corpora lutea of pregnancy was decreased in all hypergravity groups, but the number of live fetuses at gestation day 20 or pups at term was not altered. Plasma concentrations of luteinizing hormone (LH), follicle stimulating hormone (FSH), prolactin, and progesterone were not changed at gestation day 20 or postpartum. Pituitary content of LH, FSH, and prolactin was not altered by hypergravity at gestation day 20, but LH content was significantly increased (p < 0.05) at 1.5 and 1.75 G postpartum. CONCLUSIONS: We conclude that hypergravity, up to and including 2.0 G, is compatible with maintenance of pregnancy and has minimal effects on hypophyseal parameters. Ovarian follicles are not altered by hypergravity, but corpora lutea may regress at a more rapid rate.

NASA Discipline Developmental Biology↗

Effects of Repeated Fire on Florida Oak-Saw Palmetto Scrub

Background: The dominant species of Florida oak-saw palmetto scrub sprout after burning from belowground rhizomes or fire-resistant aboveground buds with rapid reestablishment of cover. Responses to single fires are well documented; however, responses to repeated fires may differ. Fire return intervals, differences among sites, and species may influence responses. We used transect data from four sites on Kennedy Space Center/Merritt Island National Wildlife Refuge to test whether growth differed through repeated fires. Two sites burned five times in 36 years, one site burned five times in 25 years, and one burned four times in 18 years. We used linear mixed models that account for repeated measures to determine if the number of fires affected height, total cover ≥ 0.5 m and < 0.5 m, bare ground, and cover of the dominant oak (Quercus) ≥ 0.5 m and of saw palmetto (Serenoa repens) ≥ 0.5 m. We compared community composition through repeated fires using nonmetric multidimensional scaling ordination. Results: Height, total cover ≥ 0.5 m, and cover of the dominant oak ≥ 0.5 m and of saw palmetto ≥ 0.5 m increased with time since burn; total cover < 0.5 m and bare ground decreased. A quadratic term in the growth model was significant except for total cover < 0.5 m. There were site differences for all variables except bare ground. The number of fires decreased height, total cover ≥ 0.5 m, and cover of the dominant oak ≥ 0.5 and increased total cover < 0.5 m and bare ground but had no effect on cover of Serenoa repens ≥ 0.5 m. Community changes after repeated fires were similar in nonmetric multidimensional ordinations with time since burn correlated to the first or second axis. Conclusions: Scrub recovered from repeated fires at a range of intervals and seasons, but short return intervals reduced growth with responses differing among species.

Florida↗

Dipole and quadrupole anisotropy of the 2.7 K radiation

Results of measurements of the dipole and quadrupole anisotropy of the microwave background radiation are reported. Balloon-borne measurements of the temperature difference between two horn antennas pointed 90 deg apart and 45 deg from the zenith were carried out at frequencies of 24.8, 31.4 and 46.0 GHz to determine three dipole and four quadrupole parameters. When combined with data from two previous balloon flights, a dipole anisotropy of 3.78 + or - 0.30 mK in the direction 11.6 + or - 0.2 h RA, -12 + or - 5 deg dec is obtained. The measurements reveal a spectral index of 0.04 + or - 0.28 between 19.0 and 46.0 GHz, indicating that the dipole effect arises from an intrinsic anisotropy in the temperature of the background and/or a first-order Doppler shift due to solar motions. A statistically significant quadrupole effect is also detected which is attributed to the intrinsic anisotropy of the 2.7 K background.

Boughn, S. P.↗

A Search for Hot, Diffuse Gas in Superclusters

The HEA01 A2 full sky, 2-10 keV X-ray map was searched for diffuse emission correlated with the plane of the local supercluster of galaxies and a positive correlation was found at the 99% confidence level. The most obvious interpretation is that the local supercluster contains a substantial amount of hot (10(exp 8) OK), diffuse gas, i.e. ionized hydrogen, with a density on the order of 2 - 3 x 10(exp -6) ions per cubic centimeter. This density is about an order of magnitude larger than the average baryon density of the universe and is consistent with a supercluster collapse factor of 10. The implied total mass is of the order of 10(exp 16) times the mass of the sun and would constitute a large fraction of the baryonic matter in the local universe. This result supports current thinking that most of the ordinary matter in the universe is in the form of ionized hydrogen; however, the high temperature implied by the X-ray emission is at the top of the range predicted by most theories. The presence of a large amount of hot gas would leave its imprint on the Cosmic Microwave Background (CMB) via the Sunyaev-Zel'dovich (SZ) effect. A marginal decrement (-17 muK) was found in the COBE 4-year 53 GHz CMB map coincident with the plane of the local supercluster. Although the detection is only 1beta, the level is consistent with the SZ effect predicted from the hot gas. If these results are confirmed by future observations they will have important implications for the formation of large-scale structure in the universe. Three other projects related directly to the HEAO 1 map or the X-ray background in general benefited from this NASA grant. They are: (1) "Correlations between the Cosmic X-ray and Microwave Backgrounds: Constraints on a Cosmological Constant"; (2) "Cross-correlation of the X-ray Background with Radio Sources: Constraining the Large-Scale Structure of the X-ray Background"; and (3) "Radio and X-ray Emission Mechanisms in Advection Dominated Accretion Flow".

Boughn, Stephen P.↗

Effect of low-dose scopolamine on autonomic control of the heart

Background: In low doses, scopolamine paradoxically enhances parasympathetic outflow to the heart. The mechanisms which mediate this action are not fully understood. Moreover, there are conflicting data regarding the potential role of sympathetic activity. This study in 17 healthy individuals was designed to characterize the influence of low dose transdermal scopolamine on the gain of the baroreflex and respiratory heart rate reflex and to determine the role of sympathetic activity. Methods: The effect of scopolamine was analyzed in the time and frequency domain by computing heart rate variability indices. The gains of the respiratory heart rate reflex and the baroreflex were estimated simultaneously by means of a cardiovascular system identification approach using an optimized autoregressive moving average algorithm. Measurements were repeated in the upright posture to assess the influence of enhanced sympathetic activity. In six subjects ambulatory ECGs were recorded to determine whether there are diurnal variations of the effect of scopolamine. Results: Scopolamine enhances vagal modulation of heart rate through both the respiratory-heart rate reflex and the baroreflex, as the gains of both were augmented by the drug in the supine and in the upright postures. Conclusions: Scopolamine increases parasympathetic cardiac control by augmenting the gain of the respiratory-heart rate and baroreflex. This action is not attenuated in the upright posture when sympathetic tone is increased.

NASA Discipline Regulatory Physiology↗

Validation of Aquarius Measurements Using Radiative Transfer Models at L-Band

Aquarius/SAC-D was launched in June 2011 by NASA and CONAE (Argentine space agency). Aquarius includes three L-band (1.4 GHz) radiometers dedicated to measuring sea surface salinity. We report detailed comparisons of Aquarius measurements with radiative transfer model predictions. These comparisons were used as part ofthe initial assessment of Aquarius data. In particular, they were used successfully to estimate the radiometer calibration bias and stability. Further comparisons are being performed to assess the performance of models in the retrieval algorithm for correcting the effect of sources of geophysical "noise" (e.g. the galactic background, atmospheric attenuation and reflected signal from the Sun). Such corrections are critical in bringing the error in retrieved salinity down to the required 0.2 practical salinity unit (psu) on monthly global maps at 150 km by 150 km resolution. The forward models making up the Aquarius simulator have been very useful for preparatory studies in the years leading to Aquarius' launch. The simulator includes various components to compute effects ofthe following processes on the measured signal: 1) emission from Earth surfaces (ocean, land, ice), 2) atmospheric emission and absorption, 3) emission from the Sun, Moon and celestial Sky (directly through the antenna sidelobes or after reflection/scattering at the Earth surface), 4) Faraday rotation, and 5) convolution of the scene by the antenna gain patterns. Since the Aquarius radiometers tum-on in late July 2011, the simulator has been used to perform a first order validation of the data. This included checking the order of magnitude ofthe signal over ocean, land and ice surfaces, checking the relative amplitude of signal at different polarizations, and checking the variation with incidence angle. The comparisons were also used to assess calibration bias and monitor instruments calibration drift. The simulator is also being used in the salinity retrieval. For example, initial assessments of the salinity retrieved from Aquarius data showed degradation in accuracy at locations where glint from the galactic sky background was important. This was traced to an inaccurate correction for the Sky glint. We present comparisons of the simulator prediction to the Aquarius data in order to assess the performances of the models of various physical processes impacting the measurements, such as the effect of sea surface roughness, the impact of the celestial Sky and the Sun emission scattered at the rough ocean surface. We discuss what components of the simulator appear reliable and which ones need improvements. Improved knowledge on the radiative transfer models at L-band will not only lead to better salinity retrieved from Aquarius data, it will also allow be beneficial for SMOS or the upcoming SMAP mission.

Dinnat, E.↗