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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 505 records · Page 28
All sourcesNASA NTRSDOE OSTI
NASA NTRS1999

Plasma membrane ordering agent pluronic F-68 (PF-68) reduces neurotransmitter uptake and release and produces learning and memory deficits in rats

A substantial body of evidence indicates that aged-related changes in the fluidity and lipid composition of the plasma membrane contribute to cellular dysfunction in humans and other mammalian species. In the CNS, reductions in neuronal plasma membrane order (PMO) (i.e., increased plasma membrane fluidity) have been attributed to age as well as the presence of the beta-amyloid peptide-25-35, known to play an important role in the neuropathology of Alzheimer's disease (AD). These PMO increases may influence neurotransmitter synthesis, receptor binding, and second messenger systems as well as signal transduction pathways. The effects of neuronal PMO on learning and memory processes have not been adequately investigated, however. Based on the hypothesis that an increase in PMO may alter a number of aspects of synaptic transmission, we investigated several neurochemical and behavioral effects of the membrane ordering agent, PF-68. In cell culture, PF-68 (nmoles/mg SDS extractable protein) reduced [3H]norepinephrine (NE) uptake into differentiated PC-12 cells as well as reduced nicotine stimulated [3H]NE release. The compound (800-2400 microg/kg, i.p., resulting in nmoles/mg SDS extractable protein in the brain) decreased step-through latencies and increased the frequencies of crossing into the unsafe side of the chamber in inhibitory avoidance training. In the Morris water maze, PF-68 increased the latencies and swim distances required to locate a hidden platform and reduced the time spent and distance swam in the previous target quadrant during transfer (probe) trials. PF-68 did not impair performance of a well-learned working memory task, the rat delayed stimulus discrimination task (DSDT), however. Studies with 14C-labeled PF-68 indicated that significant (pmoles/mg wet tissue) levels of the compound entered the brain from peripheral (i.p.) injection. No PF-68 related changes were observed in swim speeds or in visual acuity tests in water maze experiments, rotorod performance, or in tests of general locomotor activity. Furthermore, latencies to select a lever in the DSDT were not affected. These results suggest that PF-68 induced deficits in learning and memory without confounding peripheral motor, sensory, or motivational effects at the tested doses. Furthermore, none of the doses induced a conditioned taste aversion to a novel 0.1% saccharin solution indicating a lack of nausea or gastrointestinal malaise induced by the compound. The data indicate that increases in neuronal plasma membrane order may have significant effects on neurotransmitter function as well as learning and memory processes. Furthermore, compounds such as PF-68 may also offer novel tools for studying the role of neuronal PMO in mnemonic processes and changes in PMO resulting from age-related disorders such as AD.

Poloxamer/pharmacology↗
NASA NTRS1977

Flight investigation of a vertical-velocity command system for VTOL aircraft

A flight investigation was undertaken to assess the potential benefits afforded by a vertical-velocity command system (VVCS) for VTOL (vertical take-off and landing) aircraft. This augmentation system was conceived primarily as a means of lowering pilot workload during decelerating approaches to a hover and/or landing under category III instrument meteorological conditions. The scope of the investigation included a determination of acceptable system parameters, a visual flight evaluation, and an instrument flight evaluation which employed a 10 deg, decelerating, simulated instrument approach task. The results indicated that the VVCS, which decouples the pitch and vertical degrees of freedom, provides more accurate glide-path tracking and a lower pilot workload than does the unaugmented system.

Kelly, J. R.↗
NASA NTRS1980

Objective measurement of human tolerance to +G sub z acceleration stress

The efficacy of a new objective technique using a transcutaneous Doppler flowmeter to monitor superficial temporal artery blood flow velocity during acceleration was investigated. The results were correlated with current objective and subjective G tolerance end points. In over 1300 centrifuge runs, retrograde eye level blood flow leading to total flow cessation was consistently recorded and preceded visual field deterioration leading to blackout by 3 to 23 seconds. The new method was successfully applied as an objective indication of tolerance in a variety of test situations including evaluation of g-suits, straining maneuvers, and 13 deg, 45 deg and 65 deg set back angles.

Rositano, S. A.↗
NASA NTRS1980

Thresholds for detection of constant rotary acceleration during vibratory rotary acceleration

The effects of vibratory angular acceleration on detection thresholds for constant angular acceleration in a dynamic flight simulator are reported in three experiments. Detection thresholds were determined for 10 pilots and four nonpilots using a random, double-staircase procedure while the subjects sat erect in a device which rotated about an earth-vertical axis. Constant angular acceleration were presented for 0.5 and 1.0 s with concurrent, vibratory angular acceleration at 1 and 5 Hz, and thresholds with no vibratory angular acceleration were established. The thresholds were obtained while the subjects observed a visual reference in the enclosed cockpit in two experiments and in total darkness in a third. The results confirmed earlier experiments showing an inverse relationship between the duration of constant angular acceleration and detection threshold and showed that the detection thresholds in darkness were higher than with a visual reference present. Two analyses of variance revealed no significant differences in thresholds across the three vibration conditions. These results indicate that vibratory angular acceleration of fairly high levels can be present in a dynamic flight simulator without masking the pilot's ability to detect either maneuver or disturbance motions.

Clark, B.↗
NASA NTRS1982

Phenomenological study of subsonic turbulent flow over a swept rearward-facing step

The phenomenology of turbulent, subsonic flow over a swept, rearward-facing step was studied. Effects of variations in step height, sweep angle, base geometry, and end conditions on the 3-D separated flow were examined. The separated flow was visualized using smoke wire, oil drop, and surface tuft techniques. Measurements include surface pressure, reattachment distance and swirl angle. Results indicate: (1) model/test section coupling affects the structure of the separated flow, but spanwise end conditions do not; (2) the independence principle is evidently valid for sweep angles up to 38 deg; (3) a sweep angle/swirl angle correlation exists; and (4) base modifications can significantly reduce the reattachment distance.

Selby, G. V.↗
NASA NTRS1984

Investigation of several aspects of LANDSAT 4/5 data quality

A technique under development uses a zoom transfer scope to register the photograph of the target with digitally enlarged photographic hardcopy of the TM data using a visual fit to the area surrounding the target. The first attempt using the Sacramento Scene (44/33) of February 1, 1983 indicated that relief displacement in the aerial photography would cause large errors. A second attempt is in progress using the aero-triangulated scene centers which have no relief displacement. Being calculated points, the scene centers have somewhat larger absolute errors in geolocation, approximately 3 meters instead of 1.5 meters. The average TM effective instantaneous field of view (EIFOV) calculated from modulation transfer functions (MTFs) is 52.7 m. This is smaller than the 55 and 65 m EIFOVs reported earlier using noisy MTFs but larger than the EIFOVs from the San Mateo Bridge analysis which ranged from 44.5 to 50.9 m and averaged 47.6 m for the same TM scene.

Wrigley, R. C.↗
NASA NTRS1986

Vapor-screen flow-visualization experiments in the NASA Langley 0.3-m transonic cryogenic tunnel

The vortical flow on the leeward side of a delta-wing model has been visualized at several different tunnel conditions in the NASA Langley 0.3-Meter Transonic Cryogenic Tunnel using a vapor-screen flow-visualization technique. Vapor-screen photographs of the subject flow field are presented and interpreted relative to phenomenological implications. Results indicate that the use of nitrogen fog in conjunction with the vapor-screen technique is feasibile.

Selby, G. V.↗
NASA NTRS1987

Effects of proposed preflight adaptation training on eye movements, self-motion perception, and motion sickness - A progress report

The preflight adaptation trainer (PAT) was designed to produce rearranged relationships between visual and otolith signals analogous to those experienced in space. Investigations have been undertaken with three prototype trainers. The results indicated that exposure to the PAT sensory rearrangement altered self-motion perception, induced motion sickness, and changed the amplitude and phase of the horizontal eye movements evoked by roll stimulation. However, the changes were inconsistent.

Parker, D. E.↗
NASA NTRS1988

Control of leading edge vortex breakdown by blowing

An investigation into the effects of using a jet of air to control the vortex breakdown position on a 70 degree delta wing is presented. The specific objectives focused on optimizing the blowing positions in terms of maximum lift increments obtained for minimum blowing rates. The tests were conducted at chord Reynolds numbers of 150,000, 200,000, and 250,000 at angles of incidence of 30 and 35 degrees. Visualization and force data is presented to show the effect of the jet on the wing aerodynamic characteristics. The results indicate a jet position located at and aligned parallel to the leading edge to be the optimum. Nearness to the apex and tangency to the upper surface were also crucial factors. The influence of the jet on the leading edge vortex structure was examined using laser Doppler anemometry. Velocity surveys through the vortex showed that at high blowing rates the parallel velocity in the outer swirling region of the vortex increased and the normal velocity decreased. This resulted in a decrease in the swirling angle in the outer region. The peak core velocity was reduced and the vortex breakdown was delayed.

Visser, K. D.↗
NASA NTRS1990

Qualitative evaluation of a conformal velocity vector display for use at high angles-of-attack in fighter aircraft

A piloted simulation study was conducted to evaluate the utility of a display device designed to illustrate graphically and conformally the approximate location of a fighter aircraft's velocity vector. The display device consisted of two vertical rows of light emitting diodes (LED's) located toward the center of the cockpit instrument panel to each side of the control stick. The light strings provided a logical extension of the head up display (HUD) velocity vector symbol at flight path angles which exceeded the HUD field-of-view. Four test subjects flew a modified F/A-18 model with this display in an air-to-air engagement task against an equally capable opponent. Their responses to a questionnaire indicated that the conformal velocity vector information could not be used during the scenarios investigated due to the inability to visually track a target and view the lights simultaneously.

Jones, Denise R.↗
NASA NTRS1990

KOH concentration effect on the cycle life of nickel-hydrogen cells. IV - Results of failure analysis

Potassium hydroxide concentration effects on the cycle life of a Ni/H2 cell have been studied by carrying out a cycle life test on ten Ni/H2 boiler plate cells which contain electrolytes of various KOH concentrations. Failure analyses of these cells were carried out after completion of the life test, which accumulated up to 40,000 cycles at an 80-percent depth of discharge over a period of 3.7 years. These failure analyses included studies on changes of electrical characteristics of test cells, and component analyses after disassembly of the cell. The component analyses included visual inspections, dimensional changes, capacity measurements of nickel electrodes, scanning electron microscopy, surface area measurements, and chemical analyses. Results have indicated that failure mode and change in the nickel electrode varied as the concentration was varied, especially when the concentration was changed from 31 percent or higher to 26 percent or lower.

Lim, H. S.↗
NASA NTRS1990

Experimental investigation of a single flush-mounted hypermixing nozzle

The results of an experimental wind tunnel investigation of a circular supersonic jet (m sub j = 3.47) injected at a 10 degree angle into a supersonic freestream. The jet penetrates a boundary layer, which has a thickness approximately the same as the jet nozzle exit diameter. Measurements were made for nominal freestream Mach numbers of 1.6, 2.0, 2.5, and 3.0. Three jet total pressures were run at each freestream Mach number, resulting in twelve separate operating conditions. Mean data accumulated by means of static and total pressure probe instrumentation are presented at two axial stations: seven jet nozzle diameters upstream and 15 jet nozzle diameters downstream from where the centerline of the nozzle intersects the wind tunnel wall. For one condition at each freestream Mach number, the jet air was seeded with a hydrocarbon trace gas and the flow was sampled at the downstream measurement plane to quantify the mean mixing of the two streams. Surface oil flow visualization was also used to investigate the flow interaction. All results are for air-to-air mixing. The measurements indicate the presence of two pairs contra-rotating vortices. One pair follows the jet trajectory and tends to split the jet into two streams. A smaller pair, rotating in an opposite sense, develops in the near wall region. Reported results include Mach number and volume fraction distributions in the cross plane, as well as jet penetration and mixing efficiency.

Davis, David O.↗
NASA NTRS1991

Flow visualization studies of the internal flow characteristics in a simulated mixed flow vectored thrust ASTOVL engine configuration

The characteristics of internal flowfields in a Mixed Flow Vectored Thrust (MFVT) propulsion system for Short Take Off and Vertical Landing (STOVL) fighter aircraft were investigated using flow visualization techniques. A highly parametric 14 percent scale transparent model was used to simulate the MFVT propulsion system. The working medium was water. The mixing between the fan and core flow was studied using flow visualization for a variety of geometrical and flow parameters including three bypass ratio variations. The flow visualization technique involves the use of laser light sheet for illumination and fluorescent dye or air bubbles as tracers. Results indicate the existence of a strong vortex flowfield in the hover mode of operation that is responsible for good mixing between the fan and core flows.

Saripalli, K. R.↗
NASA NTRS1994

Investigation of a Laminar Flow Leading Edge

The recent resurgence of interest in utilizing laminar flow on aircraft surfaces for reduction in skin friction drag has generated a considerable amount of research in natural laminar flow (NLF) and hybrid laminar flow control (HLFC) on transonic aircraft wings. This research has focused primarily on airfoil design and understanding transition behavior with little concern for the surface imperfections and manufacturing variations inherent to most production aircraft. In order for laminar flow to find wide-spread use on production aircraft, techniques for constructing the wings must be found such that the large surface imperfections present in the leading edge region of current aircraft do not occur. Toward this end, a modification to existing leading edge construction techniques was devised such that the resulting surface did not contain large gaps and steps as are common on current production aircraft of this class. A lowspeed experiment was first conducted on a simulation of the surface that would result from this construction technique. Preston tube measurements of the boundary layer downstream of the simulated joint and flow visualization using sublimation chemicals validated the literature on the effects of steps on a laminar boundary layer. These results also indicated that the construction technique was indeed compatible with laminar flow. In order to fully validate the compatibility of this construction technique with laminar flow, thus proving that it is possible to build wings that are smooth enough to be used on business jets and light transports in a manner compatible with laminar flow, a flight experiment is being conducted. In this experiment Mach number and Reynolds number will be matched in a real flight environment. The experiment is being conducted using the NASA Dryden F-104 Flight Test Fixture (FTF). The FTF is a low aspect ratio ventral fin mounted beneath an F-104G research aircraft. A new nose shape was designed and constructed for this experiment. This nose shape provides an accelerating pressure gradient in the leading edge region. By flying the aircraft at appropriate Mach numbers and altitudes, this nose shape simulates the leading edge region of a laminar flow wing for a business jet or light transport. Manufactured into the nose shape is a spanwise slot located approximately four inches downstream of the leading edge. The slot, which is an inch wide and one-eighth of an inch deep allows the simulation of surface imperfections, such as gaps and steps at skin joints, which will occur on aircraft using this new construction technique. By placing strips of aluminum of various sizes and shapes in the slot, the effect on the boundary layer of different sizes and shapes of steps and gaps will be examined. It is planned to use five different configurations, differing primarily in the size and number of gaps. Downstream of the slot, the state of the boundary layer is determined using hot film gages and Stanton gages. Agreement between these two very different techniques of measuring boundary layer properties is considered important to being able to state with confidence the effects on the boundary layer of the simulated manufacturing imperfections. To date, the aircraft has not flown. First flights of the aircraft are on schedule to begin October 4, 1993. Low-speed, preliminary experiments at matching Reynolds numbers have been completed.

Drake, Aaron↗
NASA NTRS1960

A Visual Technique for Determining Qualitative Aerodynamic Heating Rates on Complex Configurations

An experimental investigation was conducted at a test-section Mach number of 4.95 and a stagnation temperature of 400 F to evaluate a visual technique for obtaining qualitative aerodynamic heat-transfer data on complex configurations.This technique utilized a temperature-sensetive paint indicated that this technique was satisfactory for determining qualitative heat-transfer rates on various bodies, some of which exhibited complex flow patterns. The results obtained have been found useful to guide the instrumentation of quantitative heat-transfer models, to supplement quantitative heat-transfer measurements, and to make preliminary heat-transfer studies for new configurations.

P. Calvin Stainback↗
NASA NTRS1995

The effects of spaceflight on open-loop and closed-loop postural control mechanisms: human neurovestibular studies on SLS-2

Stabilogram-diffusion analysis was used to examine how prolonged periods in microgravity affect the open-loop and closed-loop postural control mechanisms. It was hypothesized that following spaceflight: (1) the effective stochastic activity of the open-loop postural control schemes in astronauts is increased; (2) the effective stochastic activity and uncorrelated behavior, respectively, of the closed-loop postural control mechanisms in astronauts are increased; and (3) astronauts utilized open-loop postural controls schemes for shorter time intervals and smaller displacements. Four crew members and two alternates from the 14-day Spacelab Life Sciences 2 Mission were included in the study. Each subject was tested under eyes-open, quiet-standing conditions on multiple preflight and postflight days. The subjects' center-of-pressure trajectories were measured with a force platform and analyzed according to stabilogram-diffusion analysis. It was found that the effective stochastic activity of the open-loop postural control schemes in three of the four crew members was increased following spaceflight. This result is interpreted as an indication that there may be in-flight adaptations to higher-level descending postural control pathways, e.g., a postflight increase in the tonic activation of postural muscles. This change may also be the consequence of a compensatory (e.g., "stiffening") postural control strategy that is adopted by astronauts to account for general feeling of postflight unsteadiness. The crew members, as a group, did not exhibit any consistent preflight/postflight differences in the steady-state behavior of their closed-loop postural control mechanisms or in the functional interaction of their open-loop and closed-loop postural control mechanisms. These results are interpreted as indications that although there may be in-flight adaptations to the vestibular system and/or proprioceptive system, input from the visual system can compensate for such changes during undisturbed stance.

NASA Program Flight↗
NASA NTRS1997

Atypical form of Alzheimer's disease with prominent posterior cortical atrophy: a review of lesion distribution and circuit disconnection in cortical visual pathways

In recent years, the existence of visual variants of Alzheimer's disease characterized by atypical clinical presentation at onset has been increasingly recognized. In many of these cases post-mortem neuropathological assessment revealed that correlations could be established between clinical symptoms and the distribution of neurodegenerative lesions. We have analyzed a series of Alzheimer's disease patients presenting with prominent visual symptomatology as a cardinal sign of the disease. In these cases, a shift in the distribution of pathological lesions was observed such that the primary visual areas and certain visual association areas within the occipito-parieto-temporal junction and posterior cingulate cortex had very high densities of lesions, whereas the prefrontal cortex had fewer lesions than usually observed in Alzheimer's disease. Previous quantitative analyses have demonstrated that in Alzheimer's disease, primary sensory and motor cortical areas are less damaged than the multimodal association areas of the frontal and temporal lobes, as indicated by the laminar and regional distribution patterns of neurofibrillary tangles and senile plaques. The distribution of pathological lesions in the cerebral cortex of Alzheimer's disease cases with visual symptomatology revealed that specific visual association pathways were disrupted, whereas these particular connections are likely to be affected to a less severe degree in the more common form of Alzheimer's disease. These data suggest that in some cases with visual variants of Alzheimer's disease, the neurological symptomatology may be related to the loss of certain components of the cortical visual pathways, as reflected by the particular distribution of the neuropathological markers of the disease.

Review↗
NASA NTRS2000

Leonid Storm Flux Analysis From One Leonid MAC Video AL50R

A detailed meteor flux analysis is presented of a seventeen-minute portion of one videotape, collected on November 18, 1999, during the Leonid Multi-instrument Aircraft Campaign. The data was recorded around the peak of the Leonid meteor storm using an intensified CCD camera pointed towards the low southern horizon. Positions of meteors on the sky were measured. These measured meteor distributions were compared to a Monte Carlo simulation, which is a new approach to parameter estimation for mass ratio and flux. Comparison of simulated flux versus observed flux levels, seen between 1:50:00 and 2:06:41 UT, indicate a magnitude population index of r = 1.8 +/- 0.1 and mass ratio of s = 1.64 +/- 0.06. The average spatial density of the material contributing to the Leonid storm peak is measured at 0.82 +/- 0.19 particles per square kilometer per hour for particles of at least absolute visual magnitude +6.5. Clustering analysis of the arrival times of Leonids impacting the earth's atmosphere over the total observing interval shows no enhancement or clumping down to time scales of the video frame rate. This indicates a uniformly random temporal distribution of particles in the stream encountered during the 1999 epoch. Based on the observed distribution of meteors on the sky and the model distribution, recommendations am made for the optimal pointing directions for video camera meteor counts during future ground and airborne missions.

Gural, Peter S.↗