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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 523 records · Page 29
All sourcesNASA NTRSDOE OSTI
DOE OSTI2020

Development and validation of a 30-day mortality index based on pre-existing medical administrative data from 13,323 COVID-19 patients: The Veterans Health Administration COVID-19 (VACO) Index

Background Available COVID-19 mortality indices are limited to acute inpatient data. Using nationwide medical administrative data available prior to SARS-CoV-2 infection from the US Veterans Health Administration (VA), we developed the VA COVID-19 (VACO) 30-day mortality index and validated the index in two independent, prospective samples. Methods and findings We reviewed SARS-CoV-2 testing results within the VA between February 8 and August 18, 2020. The sample was split into a development cohort (test positive between March 2 and April 15, 2020), an early validation cohort (test positive between April 16 and May 18, 2020), and a late validation cohort (test positive between May 19 and July 19, 2020). Our logistic regression model in the development cohort considered demographics (age, sex, race/ethnicity), and pre-existing medical conditions and the Charlson Comorbidity Index (CCI) derived from ICD-10 diagnosis codes. Weights were fixed to create the VACO Index that was then validated by comparing area under receiver operating characteristic curves (AUC) in the early and late validation cohorts and among important validation cohort subgroups defined by sex, race/ethnicity, and geographic region. We also evaluated calibration curves and the range of predictions generated within age categories. 13,323 individuals tested positive for SARS-CoV-2 (median age: 63 years; 91% male; 42% non-Hispanic Black). We observed 480/3,681 (13%) deaths in development, 253/2,151 (12%) deaths in the early validation cohort, and 403/7,491 (5%) deaths in the late validation cohort. Age, multimorbidity described with CCI, and a history of myocardial infarction or peripheral vascular disease were independently associated with mortality–no other individual comorbid diagnosis provided additional information. The VACO Index discriminated mortality in development (AUC = 0.79, 95% CI: 0.77–0.81), and in early (AUC = 0.81 95% CI: 0.78–0.83) and late (AUC = 0.84, 95% CI: 0.78–0.86) validation. The VACO Index allows personalized estimates of 30-day mortality after COVID-19 infection. For example, among those aged 60–64 years, overall mortality was estimated at 9% (95% CI: 6–11%). The Index further discriminated risk in this age stratum from 4% (95% CI: 3–7%) to 21% (95% CI: 12–31%), depending on sex and comorbid disease. Conclusion Prior to infection, demographics and comorbid conditions can discriminate COVID-19 mortality risk overall and within age strata. The VACO Index reproducibly identified individuals at substantial risk of COVID-19 mortality who might consider continuing social distancing, despite relaxed state and local guidelines.

60 APPLIED LIFE SCIENCES↗
DOE OSTI2024

Correlations between azimuthal anisotropy and mean transverse momentum in pp, pPb, and peripheral PbPb collisions

Correlations between azimuthal anisotropy and mean transverse momentum of charged particles in proton-proton (pp), proton-lead (pPb), and peripheral lead-lead (PbPb) collisions are presented as a function of charged particle multiplicity. The pp, pPb and PbPb collision data were collected using the CMS detector at the LHC with a center-of-mass energy per nucleon pair of 13, 8.16 and 5.02 TeV, respectively. The two- and four-particle cumulants for the second- and third-order Fourier anisotropy harmonics are correlated with the mean transverse momentum of charged particles on an event-by-event basis. In pp and pPb systems, the observed correlation coefficients based on two-particle cumulants are found to change from negative to positive values as the charged particle multiplicity decreases. The sign changes disappear when the correlated particles are required to be further apart in pseudorapidity. Additionally, no sign changes in correlation coefficients are observed when employing four-particle cumulants. Models incorporating initial-state gluon saturation and final-state hydrodynamic evolutions are compared to pPb data and the predicted sign changes are not observed.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗
NASA NTRS1996

Spatial variation of the 3.29 and 3.40 micron emission bands within reflection nebulae and the photochemical evolution of methylated polycyclic aromatic hydrocarbons

Spectra of 3 micrometers emission features have been obtained at several positions within the reflection nebulae NGC 1333 SVS3 and NGC 2023. Strong variations of the relative intensities of the 3.29 micrometers feature and its most prominent satellite band at 3.40 micrometers are found. It is shown that (i) the 3.40 micrometers band is too intense with respect to the 3.29 micrometers band at certain positions to arise from hot band emission alone, (ii) the 3.40 micrometers band can be reasonably well matched by new laboratory spectra of gas-phase polycyclic aromatic hydrocarbons (PAHs) with alkyl (-CH3) side groups, and (iii) the variations in the 3.40 micrometers to 3.29 micrometers band intensity ratios are consistent with the photochemical erosion of alkylated PAHs. We conclude that the 3.40 micrometers emission feature is attributable to -CH3 side groups on PAH molecules. We predict a value of 0.5 for the peak intensity ratio of the 3.40 and 3.29 micrometers emission bands from free PAHs in the diffuse interstellar medium, which would correspond to a proportion of one methyl group for four peripheral hydrogens. We also compare the 3 micrometers spectrum of the proto-planetary nebula IRAS 05341+0852 with the spectrum of the planetary nebula IRAS 21282+5050. We suggest that a photochemical evolution of the initial aliphatic and aromatic hydrocarbon mixture formed in the outflow is responsible for the changes observed in the 3 micrometers emission spectra of these objects.

NASA Center ARC↗
DOE OSTI2015

Tight junction disruption by cadmium in an in vitro human airway tissue model

The cadmium (Cd) present in air pollutants and cigarette smoke has the potential of causing multiple adverse health outcomes involving damage to pulmonary and cardiovascular tissue. Injury to pulmonary epithelium may include alterations in tight junction (TJ) integrity, resulting in impaired epithelial barrier function and enhanced penetration of chemicals and biomolecules. Herein, we investigated mechanisms involved in the disruption of TJ integrity by Cd exposure using an in vitro human air-liquid-interface (ALI) airway tissue model derived from normal primary human bronchial epithelial cells. ALI cultures were exposed to noncytotoxic doses of CdCl 2 basolaterally and TJ integrity was measured by Trans-Epithelial Electrical Resistance (TEER) and immunofluorescence staining with TJ markers. PCR array analysis was used to identify genes involved with TJ collapse. To explore the involvement of kinase signaling pathways, cultures were treated with CdCl 2 in the presence of kinase inhibitors specific for cellular Src or Protein Kinase C (PKC). Noncytotoxic doses of CdCl 2 resulted in the collapse of barrier function, as demonstrated by TEER measurements and Zonula occludens-1 (ZO-1) and occludin staining. CdCl 2 exposure altered the expression of several groups of genes encoding proteins involved in TJ homeostasis. In particular, down-regulation of select junction-interacting proteins suggested that a possible mechanism for Cd toxicity involves disruption of the peripheral junctional complexes implicated in connecting membrane-bound TJ components to the actin cytoskeleton. Inhibition of kinase signaling using inhibitors specific for cellular Src or PKC preserved the integrity of TJs, possibly by preventing occludin tyrosine hyperphosphorylation, rather than reversing the down-regulation of the junction-interacting proteins. Our findings indicate that acute doses of Cd likely disrupt TJ integrity in human ALI airway cultures both through occludin hyperphosphorylation via kinase activation and by direct disruption of the junction-interacting complex.

60 APPLIED LIFE SCIENCES↗
DOE OSTI2013

55Fe effect on enhancing ferritic steel He/dpa ratio in fission reactor irradiations to simulate fusion conditions

How to increase the ferritic steel He(appm)/dpa ratio in a fission reactor neutron spectrum is an important question for fusion reactor material testing. An early experiment showed that the accelerated He(appm)/dpa ratio of about 2.3 was achieved for 96% enriched 54Fe in iron with 458.2 effective full power days (EFPD) irradiation in the High Flux Isotope Reactor (HFIR), ORNL. Greenwood suggested that the transmutation produced 55Fe has a thermal neutron helium production cross section which may have an effect on this result. In the current work, the ferritic steel He(appm)/dpa ratio is studied in the neutron spectrum of HFIR with 55Fe thermal neutron helium production taken into account. The available ENDF-b format 55Fe incident neutron cross section file from TENDL, Netherlands, is first input into the calculation model. A benchmark calculation for the same sample as used in the aforementioned experiment was used to adjust and evaluate the TENDL 55Fe (n, a) cross section values. The analysis shows a decrease of a factor of 6700 for the TENDL 55Fe (n, a) cross section in the intermediate and low energy regions is required in order to fit the experimental results. The best fit to the cross section value at thermal neutron energy is about 27 mb. With the adjusted 55Fe (n, a) cross sections, calculation show that the 54Fe and 55Fe isotopes can be enriched by the isotopic tailoring technique in a ferritic steel sample irradiated in HFIR to significantly enhance the helium production rate. The results show that a 70% enriched 54Fe and 30% enriched 55Fe ferritic steel sample would produce a He(appm)/dpa ratio of about 13 initially in the HFIR peripheral target position (PTP). After one year irradiation, the ratio decreases to about 10. This new calculation can be used to guide future isotopic tailoring experiments designed to increase the He(appm)/dpa ratio in fission reactors. A benchmark experiment is suggested to be performed to evaluate the 55Fe (n, a) cross section at thermal energy.

55Fe(n,helium) reaction, He(appm)/dpa ratio, isoto↗
DOE OSTI2012

Exploring the anti-inflammatory activity of a novel 2-phenylquinazoline analog with protection against inflammatory injury

Inflammation is a protective immune response against harmful stimuli whose long time continuation results in host disease. Quinazolinones are nitrogen containing heterocyclic compounds with wide spectrum of biological activities. The anticancer effect of a 3-(arylideneamino)‐phenylquinazoline-4(3H)-one derivative was reported earlier. The anti-inflammatory effect of these quinazolinone derivatives has now been examined in endotoxin stimulated macrophages and in different in vivo models of inflammation by measuring the proinflammatory cytokines (TNF-α, IL-1β and IL-6), mediators NO and NF-κB (by ELISA and western blot), and translocation of the nuclear factor kB (by immunocytochemical analysis). To elucidate the in vivo effect, mice endotoxin model was and the various levels of edema, inflammatory pain and vascular permeability were studied. One of the quinazolinone derivatives showed significant anti-inflammatory activity in stimulated macrophage cells by inhibiting the expression of TNF-α, IL-1β, IL-6, iNOS, COX-2, p-IκB and NF-κBp65. Significant (P < 0.01) improvement was observed in the mortality of endotoxemic mice. The carrageenan and formalin-induced paw edema thicknesses were found to be reduced significantly (P < 0.01) along with the reduction of pain, vascular permeability and edema induced by complete Freund's adjuvant (P < 0.01). These findings indicate that 3-(arylideneamino)‐phenylquinazoline-4(3H)-one derivative as a potential anti-inflammatory agent. -- Highlights: ► 2-phenylquinazoline analog suppresses the cytokines in stimulated macrophages. ► 2-phenylquinazoline analog down regulated NF-kB P65 translocation. ► Role of 2-phenylquinazoline analog in endotoximia and peripheral inflammations.

60 APPLIED LIFE SCIENCES↗
DOE OSTI2016

Impact of bowtie filter and object position on the two-dimensional noise power spectrum of a clinical MDCT system

Purpose: Noise characteristics of clinical multidetector CT (MDCT) systems can be quantified by the noise power spectrum (NPS). Although the NPS of CT has been extensively studied in the past few decades, the joint impact of the bowtie filter and object position on the NPS has not been systematically investigated. This work studies the interplay of these two factors on the two dimensional (2D) local NPS of a clinical CT system that uses the filtered backprojection algorithm for image reconstruction. Methods: A generalized NPS model was developed to account for the impact of the bowtie filter and image object location in the scan field-of-view (SFOV). For a given bowtie filter, image object, and its location in the SFOV, the shape and rotational symmetries of the 2D local NPS were directly computed from the NPS model without going through the image reconstruction process. The obtained NPS was then compared with the measured NPSs from the reconstructed noise-only CT images in both numerical phantom simulation studies and experimental phantom studies using a clinical MDCT scanner. The shape and the associated symmetry of the 2D NPS were classified by borrowing the well-known atomic spectral symbols s, p, and d, which correspond to circular, dumbbell, and cloverleaf symmetries, respectively, of the wave function of electrons in an atom. Finally, simulated bar patterns were embedded into experimentally acquired noise backgrounds to demonstrate the impact of different NPS symmetries on the visual perception of the object. Results: (1) For a central region in a centered cylindrical object, an s-wave symmetry was always present in the NPS, no matter whether the bowtie filter was present or not. In contrast, for a peripheral region in a centered object, the symmetry of its NPS was highly dependent on the bowtie filter, and both p-wave symmetry and d-wave symmetry were observed in the NPS. (2) For a centered region-ofinterest (ROI) in an off-centered object, the symmetry of its NPS was found to be different from that of a peripheral ROI in the centered object, even when the physical positions of the two ROIs relative to the isocenter were the same. (3) The potential clinical impact of the highly anisotropic NPS, caused by the interplay of the bowtie filter and position of the image object, was highlighted in images of specific bar patterns oriented at different angles. The visual perception of the bar patterns was found to be strongly dependent on their orientation. Conclusions: The NPS of CT depends strongly on the bowtie filter and object position. Even if the location of the ROI with respect to the isocenter is fixed, there can be different symmetries in the NPS, which depend on the object position and the size of the bowtie filter. For an isolated off-centered object, the NPS of its CT images cannot be represented by the NPS measured from a centered object.

60 APPLIED LIFE SCIENCES↗
DOE OSTI2016

Experimental Identification of Small Non-Coding RNAs in the Model Marine Bacterium Ruegeria pomeroyi DSS-3

In oligotrophic ocean waters where bacteria are often subjected to chronic nutrient limitation, community transcriptome sequencing has pointed to the presence of highly abundant small RNAs (sRNAs). The role of sRNAs in regulating response to nutrient stress was investigated in a model heterotrophic marine bacterium Ruegeria pomeroyi grown in continuous culture under carbon (C) and nitrogen (N) limitation. RNAseq analysis identified 99 putative sRNAs. Sixty-nine were cis-encoded and located antisense to a presumed target gene. Thirty were trans-encoded and initial target prediction was performed computationally. The most prevalent functional roles of genes anti-sense to the cis-sRNAs were transport, cell-cell interactions, signal transduction, and transcriptional regulation. Most sRNAs were transcribed equally under both C and N limitation, and may be involved in a general stress response. However, 14 were regulated differentially between the C and N treatments and may respond to specific nutrient limitations. A network analysis of the predicted target genes of the R. pomeroyi cis-sRNAs indicated that they average fewer connections than typical protein-encoding genes, and appear to be more important in peripheral or niche-defining functions encoded in the pan genome.

59 BASIC BIOLOGICAL SCIENCES↗
DOE OSTI2016

Preclinical evaluation of WYE-687, a mTOR kinase inhibitor, as a potential anti-acute myeloid leukemia agent

Mammalian target of rapamycin (mTOR) as a potential drug target for treatment of acute myeloid leukemia (AML). Here, we investigated the potential anti-leukemic activity by WYE-687, a potent mTOR kinase inhibitor. We demonstrated that WYE-687 potently inhibited survival and proliferation of established (HL-60, U937, AML-193 and THP-1 lines) and human AML progenitor cells. Yet, same WYE-687 treatment was non-cytotoxic to the primary peripheral blood mononuclear leukocytes (PBMCs) isolated from healthy donors. WYE-687 induced caspase-dependent apoptotic death in above AML cells/progenitor cells. On the other hand, the pan-caspase inhibitor (Z-VAD-FMK), the caspase-3 specific inhibitor (Z-DEVD-FMK) or the caspase-9 specific inhibitor (z-LEHD-fmk) attenuated WYE-687-induced cytotoxicity. At the molecular level, WYE-687 concurrently inhibited activation of mTORC1 (p70S6K1 and S6 phosphorylations) and mTORC2 (AKT Ser-473 and FoxO1/3a phosphorylations), whiling downregulating mTORC1/2-regulated genes (Bcl-xL and hypoxia-inducible factor 1/2α) in both HL-60/U937 cells and human AML progenitor cells. In vivo, oral administration of WYE-687 potently inhibited U937 leukemic xenograft tumor growth in severe combined immunodeficient (SCID) mice, without causing significant toxicities. In summary, our results demonstrate that targeting mTORC1/2 by WYE-687 leads to potent antitumor activity in preclinical models of AML. - Highlights: • WYE-687 inhibits survival and proliferation of human AML cells/progenitor cells. • WYE-687 induces apoptotic death of human AML cells/progenitor cells. • WYE-687 inhibits mTORC1/2 activation in human AML cells/progenitor cells. • WYE-687 inhibits U937 xenograft growth in SCID mice.

60 APPLIED LIFE SCIENCES↗
DOE OSTI2015

SU-C-BRA-07: Virtual Bronchoscopy-Guided IMRT Planning for Mapping and Avoiding Radiation Injury to the Airway Tree in Lung SAbR

Purpose: Post-treatment radiation injury to central and peripheral airways is a potentially important, yet under-investigated determinant of toxicity in lung stereotactic ablative radiotherapy (SAbR). We integrate virtual bronchoscopy technology into the radiotherapy planning process to spatially map and quantify the radiosensitivity of bronchial segments, and propose novel IMRT planning that limits airway dose through non-isotropic intermediate- and low-dose spillage. Methods: Pre- and ∼8.5 months post-SAbR diagnostic-quality CT scans were retrospectively collected from six NSCLC patients (50–60Gy in 3–5 fractions). From each scan, ∼5 branching levels of the bronchial tree were segmented using LungPoint, a virtual bronchoscopic navigation system. The pre-SAbR CT and the segmented bronchial tree were imported into the Eclipse treatment planning system and deformably registered to the planning CT. The five-fraction equivalent dose from the clinically-delivered plan was calculated for each segment using the Universal Survival Curve model. The pre- and post-SAbR CTs were used to evaluate radiation-induced segmental collapse. Two of six patients exhibited significant segmental collapse with associated atelectasis and fibrosis, and were re-planned using IMRT. Results: Multivariate stepwise logistic regression over six patients (81 segments) showed that D0.01cc (minimum point dose within the 0.01cc receiving highest dose) was a significant independent factor associated with collapse (odds-ratio=1.17, p=0.010). The D0.01cc threshold for collapse was 57Gy, above which, collapse rate was 45%. In the two patients exhibiting segmental collapse, 22 out of 32 segments showed D0.01cc >57Gy. IMRT re-planning reduced D0.01cc below 57Gy in 15 of the 22 segments (68%) while simultaneously achieving the original clinical plan objectives for PTV coverage and OAR-sparing. Conclusion: Our results indicate that the administration of lung SAbR can Result in significant injury to bronchial segments, potentially impairing post-SAbR lung function. To our knowledge, this is the first investigation of functional avoidance based on mapping and minimizing dose to individual bronchial segments. The presenting author receives research funding from Varian Medical Systems, Elekta, and VisionRT.

60 APPLIED LIFE SCIENCES↗
DOE OSTI2017

Large Longitudinal Spin Alignment of Excited Projectiles in Intermediate Energy Inelastic Scattering

Here, we study the sequential breakup of E/A = 24.0 MeV 7 Li projectiles excited through inelastic interactions with C, Be, and Al target nuclei. For peripheral events that do not excite the target, we find very large spin alignment of the excited 7 Li projectiles longitudinal to the beam axis. This spin alignment is independent of the target used, and we propose a simple alignment mechanism that arises from an angular-momentum-excitation-energy mismatch. This mechanism is independent of the potential used for scattering and should be present in many scattering experiments.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗
DOE OSTI2019

A Molecular Biology Tool Kit for the Phototrophic Firmicute Heliobacterium modesticaldum

The heliobacteria are members of the bacterial order Clostridiales and form the only group of phototrophs in the phylum Firmicutes . Several physiological and metabolic characteristics make them an interesting subject of investigation, including their minimalist photosynthetic system, nitrogen fixation abilities, and ability to reduce toxic metals. Although the species Heliobacterium modesticaldum is an excellent candidate as a model system for the family Heliobacteriaceae , since an annotated genome and transcriptomes are available, studies in this organism have been hampered by the lack of genetic tools. We adapted techniques for genetic manipulation of related clostridial species for use with H. modesticaldum . Five heliobacterial DNA methyltransferase genes were expressed in an Escherichia coli strain engineered as a conjugative plasmid donor for broad-host-range plasmids. Premethylation of the shuttle vectors before conjugation into H. modesticaldum is absolutely required for production of transconjugant colonies. The introduced shuttle vectors are maintained stably and can be recovered using a modified minipreparation procedure developed to inhibit endogenous DNase activity. Moreover, we describe the formulation of various growth media, including a defined medium for metabolic studies and isolation of auxotrophic mutants. Heliobacteria are anoxygenic phototrophic bacteria with the simplest known photosynthetic apparatus. They are unique in using bacteriochlorophyll g as their main pigment and lacking a peripheral antenna system. Until now, research on this organism has been hampered by the lack of a genetic transformation system. Without such a system, gene knockouts, site-directed mutations, and gene expression studies cannot be performed to help us further understand or manipulate the organism. Here we report the genetic transformation of a heliobacterium, which should enable future genetic studies in this unique phototrophic organism.

59 BASIC BIOLOGICAL SCIENCES↗
DOE OSTI2026

Hydration-Controlled Proton Transport in Respiratory Complex I

Proton pumping by respiratory complex I is one essential element for generating the proton motive force that drives ATP synthesis in mitochondria. Although it is understood that electrons from NADH reduce ubiquinone at the peripheral arm and that four protons are transferred in the membrane domain, the mechanism by which this redox reaction initiates proton translocation remains unclear. A lateral pathway linking the quinone binding site to the membrane domain via ND1, ND3, and ND4L subunits has been proposed as a possible initial path of an excess proton. However, experimental structures indicate that the hydration connectivity between D66 ND3 and E34 ND4L is comparatively weaker than in neighboring segments, suggesting a potential regulatory point for proton transfer. Using multiscale reactive molecular dynamics (MS-RMD) and a water wire connectivity metric, we directly simulate proton transport through this region as coupled to the hydration by water molecules. Our results reveal that proton transfer is thermodynamically feasible when transient hydration aligns with the presence of an excess proton, revealing the strong coupling between hydration and proton transfer (PT) in this region of Complex I. These findings support a model where proton injection enhances local hydration, dynamically opening the pathway for proton transfer and regulating the onset of proton pumping in Complex I.

Chemical structure↗
DOE OSTI2012

Design, Test and Demonstration of Saturable Reactor High-Temperature Superconductor Fault Current Limiters

Zenergy Power has successfully designed, built, tested, and installed in the US electrical grid a saturable reactor Fault Current Limiter. Beginning in 2007, first as SC Power Systems and from 2008 as Zenergy Power, Inc., ZP used DOE matching grant and ARRA funds to help refine the design of the saturated reactor fault current limiter. ZP ultimately perfected the design of the saturated reactor FCL to the point that ZP could reliably design a suitable FCL for most utility applications. Beginning with a very basic FCL design using 1G HTS for a coil housed in a LN2 cryostat for the DC bias magnet, the technology progressed to a commercial system that was offered for sale internationally. Substantial progress was made in two areas. First, the cryogenics cooling system progressed from a sub-cooled liquid nitrogen container housing the HTS coils to cryostats utilizing dry conduction cooling and reaching temperatures down to less than 20 degrees K. Large, round cryostats with warm bore diameters of 1.7 meters enabled the design of large tanks to hold the AC components. Second, the design of the AC part of the FCL was refined from a six legged spider design to a more compact and lighter design with better fault current limiting capability. Further refinement of the flux path and core shape led to an efficient saturated reactor design requiring less Ampere-turns to saturate the core. In conclusion, the development of the saturable reactor FCL led to a more efficient design not requiring HTS magnets and their associated peripheral equipment, which yielded a more economical product in line with the electric utility industry expectations. The original goal for the DOE funding of the ZP project Design, Test and Demonstration of Saturable Reactor High-Temperature Superconductor Fault Current Limiters was to stimulate the HTS wire industry with, first 1G, then 2G, HTS wire applications. Over the approximately 5 years of ZP's product development program, the amount of HTS wire employed per FCL and its cost as a percentage of the total FCL product content had not dropped substantially from an unsustainable level of more than 50% of the total cost of the FCL, nor had the availability increased (today the availability of 2G wire for commercial applications outside of specific partnerships with the leading 2G wire manufacturers is extremely limited). ZP had projected a very significant commercial potential for FCLs with higher performance and lower costs compared to the initial models built with 1G wire, which would come about from the widespread availability of low-cost, high-performance 2G HTS wire. The potential for 2G wires at greatly reduced performance-based prices compared to 1G HTS conductor held out the potential for the commercial production of FCLs at price and performance levels attractive to the utility industry. However, the price of HTS wire did not drop as expected and today the available quantities of 2G wire are limited, and the price is higher than the currently available supplies of 1G wire. The commercial option for ZP to provide a reliable and reasonably priced FCL to the utility industry is to employ conventional resistive conductor DC electromagnets to bias the FCL. Since the premise of the original funding was to stimulate the HTS wire industry and ZP concluded that copper-based magnets were more economical for the foreseeable future, DOE and ZP decided to mutually terminate the project.

24 POWER TRANSMISSION AND DISTRIBUTION↗
DOE OSTI2014

Boundary condition for toroidal plasma flow imposed at the separatrix in high confinement JT-60U plasmas with edge localized modes and the physics process in pedestal structure formation

Modulation charge eXchange recombination spectroscopy measurements with high spatial and temporal resolution have made the evaluation of the toroidal plasma flow of fully stripped carbon impurity ions (V{sub ϕ}{sup C6+}) in the JT-60U tokamak peripheral region (including, in particular, the separatrix) possible with a better signal-to-noise ratio. By comparing co- and counter-neutral beam injection discharges experimentally, we have identified the boundary condition of V{sub ϕ}{sup C6+} and radial electric field shear (∇E{sub r}) imposed at the separatrix in high confinement (H-mode) plasmas with edge localized modes (ELMs). The V{sub ϕ}{sup C6+} value at the separatrix is not fixed at zero but varies with the momentum input direction. On the other hand, the ∇E{sub r} value is nearly zero (or very weakly positive) at the separatrix. Furthermore, the edge localized mode perturbation does not appear to affect both V{sub ϕ}{sup C6+} and ∇E{sub r} values at the separatrix as strongly as that in the pedestal region. The above experimental findings based on the precise edge measurements have been used to validate a theoretical model and develop a new empirical model. A better understanding of the physical process in the edge transport barrier (ETB) formation due to the sheared E{sub r} formation is also discussed.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗
DOE OSTI2023

Two-particle azimuthal correlations in γp interactions using pPb collisions at s NN = 8.16 TeV

The first measurements of the Fourier coefficients ( V n Δ ) of the azimuthal distributions of charged hadrons emitted from photon-proton (γp) interactions are presented. The data are extracted from 68.8 nb −1 of ultra-peripheral proton-lead (pPb) collisions at s NN = 8.16 TeV using the CMS detector. The high energy lead ions produce a flux of photons that can interact with the oncoming proton. This γp system provides a set of unique initial conditions with multiplicity lower than in photon-lead collisions but comparable to recent electron-positron and electron-proton data. The V n Δ coefficients are presented in ranges of event multiplicity and transverse momentum ( p T ) and are compared to corresponding hadronic minimum bias pPb results. For a given multiplicity range, the mean p T of charged particles is smaller in γp than in pPb collisions. For both the γp and pPb samples, V 1 Δ is negative, V 2 Δ is positive, and V 3 Δ consistent with 0. For each multiplicity and p T range, V 2 Δ is larger for γp events. The γp data are consistent with model predictions that have no collective effects.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗
NASA NTRS2023

Greenland and Canadian Arctic Ice Temperature Profiles Database

Here, we present a compilation of 95 ice temperature profiles from 85 boreholes from the Greenland ice sheet and peripheral ice caps, as well as local ice caps in the Canadian Arctic. Profiles from only 31 boreholes (36 %) were previously available in open-access data repositories. The remaining 54 borehole profiles (64 %) are being made digitally available here for the first time. These newly available profiles, which are associated with pre-2010 boreholes, have been submitted by community members or digitized from published graphics and/or data tables. All 95 profiles are now made available in both absolute (meters) and normalized (0 to 1 ice thickness) depth scales and are accompanied by extensive metadata. These metadata include a transparent description of data provenance. The ice temperature profiles span 70 years, with the earliest profile being from 1950 at Camp VI, West Greenland. To highlight the value of this database in evaluating ice flow simulations, we compare the ice temperature profiles from the Greenland ice sheet with an ice flow simulation by the Parallel Ice Sheet Model (PISM). We find a cold bias in modeled near-surface ice temperatures within the ablation area, a warm bias in modeled basal ice temperatures at inland cold-bedded sites, and an apparent underestimation of deformational heating in high-strain settings. These biases provide process level insight on simulated ice temperatures.

Greenland↗
DOE OSTI2011

Zero Liquid Discharge (ZLD) System for Flue-Gas Derived Water From Oxy-Combustion Process

Researchers at the National Energy Technology Laboratory (NETL) located in Albany, Oregon, have patented a process - Integrated Pollutant Removal (IPR) that uses off-the-shelf technology to produce a sequestration ready CO{sub 2} stream from an oxy-combustion power plant. Capturing CO{sub 2} from fossil-fuel combustion generates a significant water product which can be tapped for use in the power plant and its peripherals. Water condensed in the IPR{reg_sign} process may contain fly ash particles, sodium (from pH control), and sulfur species, as well as heavy metals, cations and anions. NETL is developing a treatment approach for zero liquid discharge while maximizing available heat from IPR. Current treatment-process steps being studied are flocculation/coagulation, for removal of cations and fine particles, and reverse osmosis, for anion removal as well as for scavenging the remaining cations. After reverse osmosis process steps, thermal evaporation and crystallization steps will be carried out in order to build the whole zero liquid discharge (ZLD) system for flue-gas condensed wastewater. Gypsum is the major product from crystallization process. Fast, in-line treatment of water for re-use in IPR seems to be one practical step for minimizing water treatment requirements for CO{sub 2} capture. The results obtained from above experiments are being used to build water treatment models.

54 ENVIRONMENTAL SCIENCES↗