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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 523 records · Page 29

Room-temperature structural studies of SARS-CoV-2 protein NendoU with an X-ray free-electron laser

NendoU from SARS-CoV-2 is responsible for the virus’s ability to evade the innate immune system by cleaving the polyuridine leader sequence of antisense viral RNA. Here we report the room-temperature structure of NendoU, solved by serial femtosecond crystallography at an X-ray free-electron laser to 2.6 Å resolution. The room-temperature structure provides insight into the flexibility, dynamics, and other intrinsic properties of NendoU, with indications that the enzyme functions as an allosteric switch. Functional studies examining cleavage specificity in solution and in crystals support the uridine-purine cleavage preference, and we demonstrate that enzyme activity is fully maintained in crystal form. Optimizing the purification of NendoU and identifying suitable crystallization conditions set the benchmark for future time-resolved serial femtosecond crystallography studies. This could advance the design of antivirals with higher efficacy in treating coronaviral infections, since drugs that block allosteric conformational changes are less prone to drug resistance.

59 BASIC BIOLOGICAL SCIENCES↗

Kinematics of Strong Discontinuities

Synthetic Aperture Radar (SAR) provides a detailed view of the Arctic ice cover. When processed with the RADARSAT Geophysical Processor System (RGPS), it provides estimates of sea ice motion and deformation over large regions of the Arctic for extended periods of time. The deformation is dominated by the appearance of linear kinematic features that have been associated with the presence of leads. The RGPS deformation products are based on the assumption that the displacement and velocity are smooth functions of the spatial coordinates. However, if the dominant deformation of multiyear ice results from the opening, closing and shearing of leads, then the displacement and velocity can be discontinuous. This presentation discusses the kinematics associated with strong discontinuities that describe possible jumps in displacement or velocity. Ice motion from SAR data are analyzed using this framework. It is assumed that RGPS cells deform due to the presence of a lead. The lead orientation is calculated to optimally account for the observed deformation. It is shown that almost all observed deformation can be represented by lead opening and shearing. The procedure used to reprocess motion data to account for leads will be described and applied to regions of the Beaufort Sea. The procedure not only provides a new view of ice deformation, it can be used to obtain information about the presence of leads for initialization and/or validation of numerical simulations.

Peterson, K.↗

The Seasat SAR Wind and Ocean Wave Monitoring Capabilities: A case study for pass 1339m

A well organized low energy 11 sec. swell system off the East Coast of the U.S. was detected with the Seasat Synthetic Aperture Radar and successfully tracked from deep water, across the continental shelf, and into shallow water. In addition, a less organized 7 sec. system was tentatively identified in the imagery. Both systems were independently confirmed with simultaneous wave spectral measurements from a research pier, aircraft laser profilometer data, and Fleet Numerical Spectral Ocean Wave Models.

Beal, R. C.↗

COVID-19 trends at the University of Tennessee: predictive insights from raw sewage SARS-CoV-2 detection and evaluation and PMMoV as an indicator for human waste

Wastewater-based epidemiology (WBE) has become a valuable tool for monitoring the prevalence of SARS-CoV-2 on university campuses. However, concerns about effectiveness of raw sewage as a COVID-19 early warning system still exist, and it’s not clear how useful normalization by simultaneous comparison of Pepper Mild Mottle Virus (PMMoV) is in addressing variations resulting from fecal discharge dilution. This study aims to contribute insights into these aspects by conducting an academic-year field trial at the student residences on the University of Tennessee, Knoxville campus, raw sewage. This was done to investigate the correlations between SARS-CoV-2 RNA load, both with and without PMMoV normalization, and various parameters, including active COVID-19 cases, self-isolations, and their combination among all student residents. Significant positive correlations between SARS-CoV-2 RNA load a week prior, during the monitoring week, and the subsequent week with active cases. Despite these correlations, normalization by PMMoV does not enhance these associations. These findings suggest the potential utility of SARS-CoV-2 RNA load as an early warning indicator and provide valuable insights into the application and limitations of WBE for COVID-19 surveillance specifically within the context of raw sewage on university campuses.

60 APPLIED LIFE SCIENCES↗

Feasibility of sea ice typing with synthetic aperture radar (SAR): Merging of Landsat thematic mapper and ERS 1 SAR satellite imagery

Earth Remote-Sensing Satellite (ERS) 1 synthetic aperture radar (SAR) and Landsat thematic mapper (TM) images were acquired for the same area in the Beaufort Sea, April 16 and 18, 1992. The two image pairs were colocated to the same grid (25-m resolution), and a supervised ice type classification was performed on the TM images in order to classify ice free, nilas, gray ice, gray-white ice, thin first-year ice, medium and thick first-year ice, and old ice. Comparison of the collocated SAR pixels showed that ice-free areas can only be classified under calm wind conditions (less than 3 m/s) and for surface winds greater than 10 m/s based on the backscattering coefficient alone. This is true for pack ice regions during the cold months of the year where ice-free areas are spatially limited and where the capillary waves that cause SAR backscatter are dampened by entrained ice crystals. For nilas, two distinct backscatter classes were found at -17 dB and at -10 dB. The higher backscattering coefficient is attributed to the presence of frost flowers on light nilas. Gray and gray-white ice have a backscatter signature similar to first-year ice and therefore cannot be distinguished by SAR alone. First-year and old ice can be clearly separated based on their backscattering coefficient. The performance of the Geophysical Processor System ice classifier was tested against the Landsat derived ice products. It was found that smooth first-year ice and rough first-year ice were not significantly different in the backscatter domain. Ice concentration estimates based on ERS 1 C band SAR showed an error range of 5 to 8% for high ice concentration regions, mainly due to misclassified ice-free and smooth first-year ice areas. This error is expected to increase for areas of lower ice concentration. The combination of C band SAR and TM channels 2, 4, and 6 resulted in ice typing performance with an estimated accuracy of 90% for all seven ice classes.

Steffen, Konrad↗

PANDEMIC: Occupancy driven predictive ventilation control to minimize energy consumption and infection risk

During the SARS-CoV-2 (COVID-19) pandemic, governments around the world have formulated policies requiring ventilation systems to operate at a higher outdoor fresh air flow rate for a sufficient time, which has led to a sharp increase in building energy consumption. Therefore, it is necessary to identify an energy-efficient ventilation strategy to reduce the risk of infection. In this study, we developed an occupant-number-based model predictive control (OBMPC) algorithm for building ventilation systems. First, we collected the occupancy and Heating, ventilation, and air conditioning system (HVAC) data from March to July 2021. Then, four different models (Auto regression moving average-based multilayer perceptron (ARMA_MLP), Recurrent neural networks (RNN), Long short-term memory networks (LSTM), and Nonhomogeneous Markov with change points detection (NH_Markov)) were used to predict the number of room occupants from 15 min to 24 h ahead with an interval output. We found that each model could predict the number of occupants with 85% accuracy using a one-person offset. Furthermore, the accuracy of 15 min of the ahead prediction could reach 95% with a one-person offset, but none of them could track abrupt changes. The occupancy prediction results were used to calculate the ventilation demand using the Wells-Riley equation, and the upper bound can maintain an infection risk lower than 2% for 93% of the day. This OBMPC model could reduce the coil load by 52.44% and shift the peak load by 3 h up to 5 kW compared with 24 × 7 h full outdoor air (OA) system when people wear masks in the space. The occupancy prediction uncertainty could cause a 9% to 26% difference in demand ventilation, a 0.3°C to 2.4°C difference in zone temperature, a 28.5% to 44.5% difference in outdoor airflow rate, and a 10.7% to 28.2% difference in coil load.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

An alternative multi-mode SAR for RADARSAT

The RADARSAT project was asked by the Canadian government in the spring of 1986 to design for reduced costs and increased radar performance as compared to the well-known baseline design. Both the Project Office and Canadian industry (lead by SPAR Aerospace of Montreal) have undertaken to meet this request, with a proposal to cabinet to be submitted in the fall of 1986. One alternative SAR concept is outlined which is under consideration for a revised RADARSAT configuration. The radar system described uses two frequencies (C&L band) over four possible modes: near range swath; far range swath; wide swath; and high resolution. Good sensitivity, resolution, and coverage are obtained with modest power and data rates. The antenna systems are relatively simple. Indeed, no break-through technological developments are needed. The design allows several mode combinations for simultaneous data collection or performance enhancement. The principal parameters are described. A nominal mean altitude of 700 km is assumed.

Raney, R. K.↗

Advanced flight computers for planetary exploration

Research concerning flight computers for use on interplanetary probes is reviewed. The history of these computers from the Viking mission to the present is outlined. The differences between ground commercial computers and computers for planetary exploration are listed. The development of a computer for the Mariner Mark II comet rendezvous asteroid flyby mission is described. Various aspects of recently developed computer systems are examined, including the Max real time, embedded computer, a hypercube distributed supercomputer, a SAR data processor, a processor for the High Resolution IR Imaging Spectrometer, and a robotic vision multiresolution pyramid machine for processsing images obtained by a Mars Rover.

Stephenson, R. Rhoads↗

Approach to derivation of SIR-C science requirements for calibration

A study undertaken to determine SIR-C (Shuttle Imaging Radar-C) science requirements for polarimetric calibration is described. A model describing the effect of miscalibration is presented, followed by a description of specific experiments and the resulting requirements levied on the system. The effects of miscalibration on some commonly used measures which can be extracted from SAR (synthetic aperture radar) data are also discussed. It is concluded that polarimetric calibration requirements are strongly application-dependent, and that a compromise must be made to maximize the domain of application of the data without prohibitive cost. Data summarizing SIR-C polarimetric calibration goals are also presented.

Dubois, Pascale↗

Multifrequency, Multipolarization External Calibration of the SIR-C/X-SAR Radars

Progress and the future plans for the following objectives are discussed: (1) Assess the accuracy at which the SIR-C/X-SAR standard data products can be calibrated through the use of ground calibrators to estimate the end-to-end system polarization calibration constants (or distortion parameters) and incorporate the constants into the data processing; (2) Study the cross-calibration between three multipolarization systems: SIR-C, the National Aeronautics and Space Administration/Jet Propulsion Laboratory (NASA/JPL) DC-8 SAR, and the University of Michigan ground-based polarimetric scatterometer; (3) Evaluate the calibration "stability" of SIR-C/X-SAR (measured by variations in the calibration constants) over the range swath width and over a specified distance in azimuth. Variations over a 12-hour period (between ascending and descending passes) will also be studied; and (4) Develop a cost-effective calibration plan including development of inexpensive polarimetric active calibrators.

Freeman, Anthony↗

Statistical Modeling of Landscape Pattern and the Effects of Coarse Spatial Resolution

Analysis of classified satellite imagery was conducted to characterize errors in estimates of area based on coarse resolution satellite imagery which are due to distortions in sizes of small fragments, and to explore the feasibility of correcting for these errors using a statistical modeling approach. Sizes of bodies of open water on European Remote-Sensing (ERS-1) synthetic aperture radar (SAR) and fire scars on Landsat Multispectral Scanner (MSS) imagery were measured using geographic information system (GIS) software. Statistical analysis of the smaller scars and ponds as observed with this imagery of relatively fine resolution demonstrated that the distribution of the sizes could be modeled by either of two types of statistical distributions-a power distribution related to fractal processes or a simple exponential distribution. A comparison of the size distribution of small burn scars as observed with Landsat with the distribution observed with the much coarser Advanced Very High Resolution Radiometer (AVHRR) imagery revealed effects of coarse resolution, each of which were associated with a particular size range, and whose net effect accounted for the bias in total burn area due to coarse spatial resolution. Size dependent area correction procedures are therefore feasible. A statistical modeling approach to area estimation, based models of the underlying and observed size distributions of fragments in the scene, may lead to a procedure which requires little or no ancillary data.

Hlavka, C. A.↗

A U.S. scientific community review of carbon cycle science gaps and opportunities to better support earth system science and carbon management

Greenhouse gas (GHG) emissions continue to grow, while natural carbon reservoirs are becoming increasingly vulnerable to anthropogenic pressures, climate extremes, and disturbance. These changes are impacting humans, ecosystems, and natural resources worldwide. Tracking and mitigating GHG emissions require a pivot to operational monitoring of regional carbon flux and stock changes. The current GHG observing system is addressing needs at two distinct scales: 1) Local scale (< 1 km), related to anthropogenic point source emissions, and 2) global scales (> 1000 km), related to land and ocean carbon sinks. More focus on intermediate (10–1000 km) scales is needed to more effectively monitor progress in reducing carbon emissions, enhancing removals, and maintaining sinks. Representatives from carbon cycle biomass and flux communities across United States government agencies and academic institutions met in September 2024 to discuss the rationale and scientific context for more effectively implementing an operational system for GHG monitoring in support of urban and national carbon management needs. To guide development of this system, we propose a multi-tiered global spaceborne observing framework for carbon flux and stock, prioritizing: 1) frequent GHG partial columns for carbon emissions and removals; 2) continuous time series and data fusion of biomass from Lidar and Synthetic Aperture Radar (SAR) for carbon stocks, and 3) expanded coverage of tropical, high latitude, and oceanic regions to monitor carbon cycle tipping points and feedbacks. This system should be complemented by expanded surface and airborne networks for oceanic and terrestrial/aquatic ecosystems for calibration, ground truthing, and study of under-sampled regions.

54 ENVIRONMENTAL SCIENCES↗

The development of inflatable array antennas

Inflatable array antennas are being developed to significantly reduce the mass, the launch vehicle's stowage volume, and the cost of future spacecraft systems. Three inflatable array antennas, recently developed for spacecraft applications, are a 3.3 m x 1.0 m L-band synthetic-aperture radar (SAR) array, a 1.0 m-diameter X-band telecom reflectarray, and a 3 m-diameter Ka-band telecom reflectarray. All three antennas are similar in construction, and each consists of an inflatable tubular frame that supports and tensions a multi-layer thin-membrane RF radiating surface with printed microstrip patches. The L-band SAR array achieved a bandwidth of 80 MHz, an aperture efficiency of 74%, and a total mass of 15 kg. The X-band reflectarray achieved an aperture efficiency of 37%, good radiation patterns, and a total mass of 1.2 kg (excluding the inflation system). The 3 m Ka-band reflectarray achieved a surface flatness of 0.1 mm RMS, good radiation patterns, and a total mass of 12.8 kg (excluding the inflation system). These antennas demonstrated that inflatable arrays are feasible across the microwave and millimeter-wave spectrums. Further developments of these antennas are deemed necessary, in particular, in the area of qualifying the inflatable structures for space-environment usage.

Inflatable array antennas↗

A Radiation-Hard 8-Channel 15-Bit 40-MSPS ADC for the ATLAS Liquid Argon Calorimeter Readout

The custom design of a radiation-hardened, 8-channel, 40-MSPS, 15-bit resolution, 14.2-bit dynamic range, 11.4-ENOB ADC data acquisition ASIC fabricated in a commercial 65-nm triple-well CMOS technology is presented. The ADC is developed for and integrates seamlessly into the readout system for the ATLAS liquid argon (LAr) calorimeter in the high-luminosity large hadron collider (HLLHC) upgrade at CERN, which will require a total of 364 936 ADC channels. A three-stage MDAC+SAR pipelined ADC architecture was designed to meet the physics requirements and scientific goals of the ATLAS experiment. The ADC is a fully self-contained data acquisition system that includes foreground calibration, digital data processing, digital control, and supporting circuitry. The measured performance shows the ADC achieves a competitive dynamic range and SNDR, and it meets or exceeds the ATLAS analog requirements. Radiation tolerance and scalability design considerations were implemented at the device-, circuit-, and system-level. Radiation-hardening-by-design techniques used include redundancy for digital circuits, the use of MiM capacitors, and a hybrid RC-DAC for the ADC core. The ADC ASIC was demonstrated to be robust against the effects of the intense radiation expected in the HL-LHC experimental environment.

DAQ↗

Data and Information Exchange System for the "Reindeer Mapper" Project

During this past year, the Reindeer Mapper Intranet system has been set up on the NASA system, 8 team members have been established, a Reindeer Mapper reference list containing 696 items has been entered, 6 power point presentations have been put on line for review among team members, 304 satellite images have been catalogued (including 16 Landsat images, 288 NDVI 10-day composited images and an anomaly series- May 1998 to December 2002, and 56 SAR CEOS S A R format files), schedules and meeting dates are being shared, students at the Nordic Sami Institute are experimenting with the system for reindeer herder indigenous knowledge sharing, and an "address book" is being developed. Several documents and presentations have been translated and made available in Russian for our Russian colleagues. This has enabled our Russian partners to utilize documents and presentations for use in their research (e.g., SAR imagery comparisons with Russian GIS of specific study areas) and discussion with local colleagues.

Maynard, Nancy↗

Comparative analysis of SARS-CoV-2 neutralization titers reveals consistency between human and animal model serum and across assays

The evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) requires ongoing monitoring to judge the ability of newly arising variants to escape the immune response. A surveillance system necessitates an understanding of differences in neutralization titers measured in different assays and using human and animal serum samples. We compared 18 datasets generated using human, hamster, and mouse serum and six different neutralization assays. Datasets using animal model serum samples showed higher titer magnitudes than datasets using human serum samples in this comparison. Fold change in neutralization of variants compared to ancestral SARS-CoV-2, immunodominance patterns, and antigenic maps were similar among serum samples and assays. Most assays yielded consistent results, except for differences in fold change in cytopathic effect assays. Hamster serum samples were a consistent surrogate for human first-infection serum samples. These results inform the transition of surveillance of SARS-CoV-2 antigenic variation from dependence on human first-infection serum samples to the utilization of serum samples from animal models.

Cell Biology↗

Current status and future developments in radar remote sensing

Some of the major initiatives and directions of remote sensing using SAR (Synthetic Aperture Radar) data alone and in conjunction with other sensors for Earth science investigations are outlined. Specific emphasis is on areas key to global monitoring using SAR data from spaceborne platforms: calibration, geophysical processing, and generation of digital elevation models. Calibration as used here encompasses end to end system characterization over the life of a sensor and characterization of data products relative to past and future sensors. Geophysical processing is defined here to include any processing which results in derived geophysical units. An additional data type, topography, which is required to complete the three dimensional view of surface properties and correct for distortions inherent in SAR is discussed. Future challenges in radar remote sensing include development of strategies to extrapolate from regional to global scale models and development of new sensor technology.

Evans, Diane L.↗

Viral Dynamic Models During COVID‐19: Are We Ready for the Next Pandemic?

Mathematical models have been used for about 30 years to improve our understanding of virus-host interaction, in particular during chronic infections. During the COVID-19 pandemic, these models have been used to provide insights into the natural history of acute SARS-CoV-2 infection, optimize antiviral treatment strategies, understand factors associated with transmission, and optimize surveillance systems. The impact of modeling has been accelerated by the availability of unprecedented multidimensional immune data from animal and human systems, which enhanced partnerships between experimentalists and theorists and led to exciting new modeling and statistical developments. In this mini review, we examine the lessons learned from the COVID-19 pandemic and discuss the main insights provided by mathematical models of viral dynamics at the different stages of the outbreak. Although we focus on respiratory infection, we also consider the new areas for development in anticipation of future acute infections from new or reemerging pathogens.

59 BASIC BIOLOGICAL SCIENCES↗