Search NASA⌕ Search

SEARCH · Search NASA

Results for “test protocol”

Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 523 records · Page 29
All sourcesNASA NTRSDOE OSTI
DOE OSTI2022

Security Enhancements for Distributed Energy Resource Systems Interconnected with Distribution Networks: Final Technical Report

The revised IEEE 1547 Standard defines new complex communication-adjustable voltage and frequency regulation and ride-through characteristics, while maintaining the general antiislanding requirement for unintentional islanding situations. Unintentional islanding is prohibited while intentional islanding is specifically allowed, thus effectively enabling microgrid operation mode. Further, IEEE 1547-2018 Standard introduces new requirements in terms of interoperability so that the DER plant/circuit segments may be seamlessly integrated with the utility networks but at the same time become vulnerable to a cyber-attack. Traditional cybersecurity measures including encryption, authentication and role-based access control may not be fully implementable to all communication protocols specified in the IEEE 1547 Standard. Therefore, in this project we have identified, researched, implemented and tested several cyberphysical approaches that rely mostly on the behavior of the DER circuit and may help with validating the incoming command and control action potentially coming through an insecure communications channel. Additionally, we have built semantic models and communications profiles for DER facilities and have implemented lightweight IEC 61850 based publisher-subscriber GOOSE messaging mechanism, with security extensions in terms of authentication and encryption. The project proposed information models for integration into UCA OpenFMB 2.0 profiles focusing on grid code compliance.

24 POWER TRANSMISSION AND DISTRIBUTION↗
DOE OSTI2016

A controlled statistical study to assess measurement variability as a function of test object position and configuration for automated surveillance in a multicenter longitudinal COPD study (SPIROMICS)

Purpose: A test object (phantom) is an important tool to evaluate comparability and stability of CT scanners used in multicenter and longitudinal studies. However, there are many sources of error that can interfere with the test object-derived quantitative measurements. Here the authors investigated three major possible sources of operator error in the use of a test object employed to assess pulmonary density-related as well as airway-related metrics. Methods: Two kinds of experiments were carried out to assess measurement variability caused by imperfect scanning status. The first one consisted of three experiments. A COPDGene test object was scanned using a dual source multidetector computed tomographic scanner (Siemens Somatom Flash) with the Subpopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS) inspiration protocol (120 kV, 110 mAs, pitch = 1, slice thickness = 0.75 mm, slice spacing = 0.5 mm) to evaluate the effects of tilt angle, water bottle offset, and air bubble size. After analysis of these results, a guideline was reached in order to achieve more reliable results for this test object. Next the authors applied the above findings to 2272 test object scans collected over 4 years as part of the SPIROMICS study. The authors compared changes of the data consistency before and after excluding the scans that failed to pass the guideline. Results: This study established the following limits for the test object: tilt index ≤0.3, water bottle offset limits of [−6.6 mm, 7.4 mm], and no air bubble within the water bottle, where tilt index is a measure incorporating two tilt angles around x- and y-axis. With 95% confidence, the density measurement variation for all five interested materials in the test object (acrylic, water, lung, inside air, and outside air) resulting from all three error sources can be limited to ±0.9 HU (summed in quadrature), when all the requirements are satisfied. The authors applied these criteria to 2272 SPIROMICS scans and demonstrated a significant reduction in measurement variation associated with the test object. Conclusions: Three operator errors were identified which significantly affected the usability of the acquired scan images of the test object used for monitoring scanner stability in a multicenter study. The authors’ results demonstrated that at the time of test object scan receipt at a radiology core laboratory, quality control procedures should include an assessment of tilt index, water bottle offset, and air bubble size within the water bottle. Application of this methodology to 2272 SPIROMICS scans indicated that their findings were not limited to the scanner make and model used for the initial test but was generalizable to both Siemens and GE scanners which comprise the scanner types used within the SPIROMICS study.

60 APPLIED LIFE SCIENCES↗
DOE OSTI2026

Selective Amnesia using Contrastive Subnet Erasure for Class Level Unlearning in Vision Models

We study concept-level forgetting in pretrained vision models: removing an entire semantic category so the system no longer recognizes that object in unseen images and contexts, rather than merely forgetting specific training examples. Prior work either applies blunt global projections or fine-tunes parameters, which can introduce collateral damage to unrelated features, add compute, and become unstable as forgetting strength increases. We introduce Contrastive Subnet Erasure (CSE), a training-free, encoder-centric edit that targets a compact set of channels most responsible for the class and attenuates them in a calibrated manner. The modification is algebraically folded into the subsequent layer, yielding no inference-time overhead and leaving task heads unchanged. To evaluate whether forgetting generalizes beyond the data used to specify the class, we introduce a cross dataset protocol in which the class is defined on a source dataset and performance is measured on a disjoint target dataset drawn from a different distribution with no shared images. This setup tests whether the model still fails to recognize the object when it looks different or appears in new scenes, and it helps avoid overfitting to patterns in the source dataset. Across CIFAR 10, CIFAR 100, and ImageNet under this protocol, CSE achieves stronger forgetting of the target class while better preserving non target utility than existing baselines in both single class and multi class settings. Overall, CSE provides a simple, stable, and deployment-ready mechanism for class-level unlearning in vision.

Kotevska, Olivera [ORNL] (ORCID:0000000316772243)↗
DOE OSTI2021

CST R9120-B 30x60 Media Pretreatment and Digestion Standard Development to Support Tank Closure Cesium Removal 1A (TCCR-1A) Operations

In support of continued operations of Savannah River Remediation’s (SRR) ion exchange process to remove radioactive cesium from Savannah River Site (SRS) dissolved saltcake, referred to as the Tank Closure Cesium Removal 1A process (TCCR-1A; containing the second set of at-tank ion exchange columns), SRNL was tasked with: 1) validating the field protocol planned for pretreating the crystalline silicotitanate (CST) ion exchange media to be used in the columns, 2) preparing CST media for use in in-tank batch contact testing, and 3) developing a digestion standard to verify complete CST dissolution prior to characterization following each in-tank batch contact test. A procedure (SRNL L29 Manual, ITS-0229) was developed previously in support of the TCCR Demonstration (which contained the first set of ion exchange columns) based on evaluations of a different CST production lot with a larger particle size range to document the protocol for pretreating CST utilizing conditions similar to what will be performed in the field.

11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗
DOE OSTI2022

Performance Evaluation of an Advanced Distributed Energy Resource Management Algorithm

This paper presents performance evaluation of a new distributed energy resource management system (DERMS) algorithm via an advanced hardware-in-the-loop (HIL) platform. The HIL platform provides realistic testing in a laboratory environment, including the accurate modeling of sub-transmission and distribution networks, the DERMS software controller, and 84 power hardware solar photovoltaic (PV) inverters, standard communication protocols, and a capacitor bank controller. The DERMS algorithm is also called, Grid-Optimization of Solar (GO-Solar) platform which includes predictive state estimation (PSE) and online multiple objective optimization (OMOO) to dispatch the legacy devices and distributed energy resources (e.g., PV). The voltage regulation performance is evaluated under three scenarios, volt-var smart inverter (baseline), and DERMS control for 100% and 30% of PV. The results show that controlling 30% of PV systems with the GO-Solar platform may provide the best balance of control performance and implementation cost.

distributed energy resource management system (DER↗
DOE OSTI2023

Performance and durability of electrically conductive tape for shingled Si heterojunction technology cells

We report electrically conductive tape (ECT) was characterized and used to assemble shingled cell strings at low temperature to achieve high reliability Pb- and Ag-free interconnections. The volume resistivity for two considered ECTs are 0.13 ± 0.06 mΩ·cm and 0.47 ± 0.20 mΩ·cm and specific contact resistances, 6.85± 2.00 mΩ·cm 2 and 6.30 ± 0.37 mΩ·cm 2 using the emerging IEC 62788-8-1 Technical Specification for assessment of electrically conductive adhesives (ECA). Durability and performance of the technology in glass–glass mini modules were evaluated with temperature cycling, damp heat testing, and combined-accelerated stress testing (CAST). Through temperature cycling (-40°C to 85°C) applying five times the mini module short-circuit current in forward bias and in the multi climate CAST protocol, there was negligible degradation of fill factor after replacing connectors at the modules' cable leads; however, CAST resulted in short circuit current loss attributed to degradation in light collection by the cells, not the ECT. The IEC 61215-2 85°C, 85% relative humidity damp heat testing showed susceptibility of the HJT cells to effects of humidity in the electroluminescence intensity around the module perimeter that degraded power performance by 4% (relative). Contrasting the IEC 61215-2 qualification testing-based damp heat testing with CAST, factors such as the optical stress of CAST may precipitate the degradation of the modules whereas the humidity levels and duration of IEC 61215-2 damp heat testing may lead to excessive levels of humidity diffused into the modules, potentially resulting in degradation that is unrepresentative of the field.

14 SOLAR ENERGY↗
DOE OSTI2019

RECENT RESULTS FROM Nb3Sn SINGLE CELL CAVITIES COATED AT JLAB

Because of superior superconducting properties (Tc ~ 18.3K, Hs h ~ 425 mT and ? ~ 3.1 meV) compared to niobium, Nb3Sn promise better RF performance (Q0 and Eacc) and/or higher operating temperature (2 K Vs 4.2 K) for SRF cavities. Nb3Sn-coated SRF cavities are produced routinely by depositing a few micron-thick Nb3Sn films inside of Nb cavities via tin vapor diffu-sion technique. Early results from Nb3Sn cavities coat-ed with this technique exhibited precipitous low field Q-slope, also known as Wuppertal slope. Several Nb3Sn single cell cavities coated at JLab appeared to exhibit similar Q-slope. RF testing of cavities and ma-terials study of witness samples were continuously used to modify the coating protocol. At best condition, we were able to produce Nb3Sn cavity with Q0 in ex-cess of ? 5×1010 at 2 K and ? 2×1010 at 4 K up the ac-celerating gradient of ~15 MV/m, without any signifi-cant Q-slope. In this presentation, we will discuss re-cent results from several Nb3Sn coated single-cell cavities linked with material studies of witness sam-ples, coating process modifications and the possible causative factors to Wuppertal slope.

Pudasaini, U.↗
DOE OSTI2025

Exploring the Use of Large Immersive Display Systems in the Nuclear Industry

Large immersive display systems play a critical role in the nuclear industry by enabling advanced training, design reviews, scientific visualization, and safety simulations. These systems, such as CAVE and powerwalls, allow engineers and operators to interact with virtual nuclear environments in real-time, providing a deeper understanding of complex systems. Their ability to simulate real-world scenarios for testing and optimization in a safe, controlled environment ensures that operators and engineers can refine process, enhance safety protocols, and troubleshoot complex challenges. This article outlines key lessons learned from deploying these systems, practical insights into their applications, and considerations for future improvements, aiming to guide their broader adoption and effective use in the nuclear industry.

99 - GENERAL AND MISCELLANEOUS↗
DOE OSTI2020

Measured Performance of Over the Range Microwave Range Hoods

The California residential building code requires kitchen exhaust ventilation to protect indoor air quality. The requirement can be met with a kitchen exhaust fan or a range hood that conforms to airflow and sound specifications based on certified, standard test results. Appliances that integrate an exhaust fan with an over the range microwave (OTRs) are popular for their space saving utility; but for years there were none with the certified performance data required for building code compliance. This project, initiated during that period, aimed to evaluate OTR models found in new California homes and compare their performance to range hoods that minimally met code requirements. The study aimed to expand on limited information available about OTR performance with a particular focus on measuring the fraction of cooktop-generated air pollutants that are captured and removed by the exhaust devices, a parameter called “capture efficiency”. Airflow and capture efficiency (CE) were measured in a simulated kitchen in Berkeley Lab’s FLEXLAB facility. Airflows were measured using several variations of a balanced-pressure flow method (Walker et al. 2001) including a protocol that had been used in the California Healthy Efficient New Gas Homes (HENGH) field study. Measurements were made for six OTRs observed in the field study, including three with certified test results (published after the start of this project) for airflow and sound. Measurements were also made on two standard range hoods with comparable airflows and costs to the OTRs, when accounting for the microwave functionality. CE was measured using the CO 2 emitted from burners while heating pots of water (POW) as a tracer and calculating the ratio of added CO 2 in the exhaust flow over the total CO 2 generated from burning fuel. Results show that OTRs generally met the California code requirements for airflow, which are the same as those of the residential ventilation standard of ASHRAE. It was determined that the field protocol used in HENGH study homes was biased low by ~14% on average. The CE performance of OTRs tested in this study were consistent with those tested under controlled conditions in prior studies, showing CE increasing with airflow and being higher for emissions occurring at the back cooktop burner(s) compared with front burner emissions. The measured CE covered a range of 40% to 85% for the front burners and 60% to 100% for the back burners. The relationship of CE to airflow for OTRs was within the range of those found for standard range hoods in this study and prior studies, with the key caveat that OTRs appear to have more consistent CE performance for emissions on the front burner.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗
DOE OSTI2024

EV SALaD 2023 Demonstration: Best Practices and Mitigations for Protecting EVSE Infrastructure

The Electric Vehicle Secure Architecture Laboratory Demonstration (EV SALaD) program is a demonstration of cybersecurity best practices for high-power electric vehicle (EV) charging infrastructure led by Idaho National Laboratory (INL), in collaboration with other DOE National Laboratories participating in the EVs at Scale Consortium.a Sandia National Laboratories (SNL) and Pacific Northwest National Laboratory (PNNL) participated in the first 2-year (FY22-23) demonstration cycle for EV SALaD. This report documents the FY23 demonstration, the second in a series of demonstrations and collaborations in deploying and operating cybersecure EV charging infrastructure. It includes a summary of improvements from the FY22 demonstration, technical analysis of the FY23 demonstration, how the research demonstrates cyber-physical and cybersecurity best practices for high-power EV charging infrastructure, and related impacts to national and energy security. For EV SALaD, the FY22 demonstration focused on the detection, ranking, and prioritization of anomalous events for high-power EV charging. The FY23 demonstration additionally included the demonstration of cybersecurity best practices, which included protection and mitigation solutions to prevent, respond, and recover from anomalous events. During the demonstrations, the multi-lab EV SALaD team conducted a Test Effect Payload (TEP)b evaluation on extreme fast charger (XFC) hardware equipped with Cerberus, a detection and response solution, to demonstrate anomaly detection and mitigation cybersecurity best practices against cyber-enabled events.

33 ADVANCED PROPULSION SYSTEMS↗
DOE OSTI2016

High throughput exploration of process-property linkages in Al-6061 using instrumented spherical microindentation and microstructurally graded samples

Recent spherical nanoindentation protocols have proven robust at capturing the local elastic-plastic response of polycrystalline metal samples at length scales much smaller than the grain size. In this work, we extend these protocols to length scales that include multiple grains to recover microindentation stress-strain curves. These new protocols are first established in this paper and then demonstrated for Al-6061 by comparing the measured indentation stress-strain curves with the corresponding measurements from uniaxial tension tests. More specifically, the scaling factors between the uniaxial yield strength and the indentation yield strength was determined to be about 1.9, which is significantly lower than the value of 2.8 used commonly in literature. Furthermore, the reasons for this difference are discussed. Second, the benefits of these new protocols in facilitating high throughput exploration of process-property relationships are demonstrated through a simple case study.

36 MATERIALS SCIENCE↗
DOE OSTI2025

Heavy-Duty Hydrogen Station Equipment Performance Device (HD HyStEP) Specifications and Design Considerations

The original Hydrogen Station Equipment Performance (HyStEP) device was commissioned in 2015 and was critical for the rapid validation of light-duty (LD) hydrogen fueling stations. As applications for hydrogen as a heavy-duty (HD) transportation fuel continue to grow, new heavy-duty stations are being developed to fuel these vehicles that require larger onboard storage tank systems to meet HD transportation demands and drive cycles. The differences in size and geometry from LD vehicles have driven the creation of new hydrogen fueling protocols that will enable safe and economical fueling of HD vehicles. With the new requirements that are set out in HD fueling protocols like SAE J601-5, a new HyStEP-like device is needed to evaluate the capabilities of high-flow hydrogen stations to fuel HD vehicles to the new protocol standard. To create a heavy-duty HyStEP (HD HyStEP) device, an effort has been undertaken to evaluate the requirements that would form the basis for the design of a successful HD HyStEP device. The primary design goal of this HD HyStEP device is its capability of following a test methodology similar to what is outlined in CSA HGV 4.3, which guides the validation of LD fueling dispensers but with adjustments to verify adherence to the HD fueling protocols (SAE J2601-5) for 70 MPa and 35 MPa pressure class vehicles rather than the LD fueling protocols (SAE J2601). The design presented here aims to provide information that enables the creation of an HD HyStEP device that achieves the primary design goal while being informed by the years of experience from the current HyStEP operators.

08 HYDROGEN↗
DOE OSTI2024

Reference Materials for Laser and Xenon Flash Thermal Diffusivity Systems

This report presents the status of current standard reference materials for thermal diffusivity testing. In most thermal properties testing systems, it is common to use standard reference materials to show the reproducibility of the tests and certify the instrument is producing results within expected uncertainty range. The definition of reference materials or standards vary depending on the quality control protocols of the project. For thermal diffusivity, although there were standards available by the National Bureau of Standards (NBS) 40 years ago, there has been no recent NIST standard reference material (SRM). There are only a few sources that produce and provide traceable reference standards for thermal diffusivity. The certificate typically expires in 5 years and only applies to the specific lot of materials. Other reference materials are provided by the testing systems manufacturers. They are mostly well-known reference materials or materials used by the equipment manufacturers with historic data. However, most these reference materials no longer carry valid certificates. Various reference materials will be discussed along with the industry practice when only secondary standards are available.

36 MATERIALS SCIENCE↗
DOE OSTI2016

Hanford Double Shell Waste Tank Corrosion Studies - Final Report FY2015

During FY15, SRNL performed corrosion testing that supported Washington River Protection Solutions (WRPS) with their double shell tank (DST) integrity program. The testing investigated six concerns including, 1) the possibility of corrosion of the exterior of the secondary tank wall; 2) the effect of ammonia on vapor space corrosion (VSC) above waste simulants; 3) the determination of the minimum required nitrite and hydroxide concentrations that prevent pitting in concentrated nitrate solutions (i.e., waste buffering); 4) the susceptibility to liquid air interface (LAI) corrosion at proposed stress corrosion cracking (SCC) inhibitor concentrations; 5) the susceptibility of carbon steel to pitting in dilute solutions that contain significant quantities of chloride and sulfate; and 6) the effect of different heats of A537 carbon steel on the corrosion response. For task 1, 2, and 4, the effect of heat treating and/ or welding of the materials was also investigated.

12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗
DOE OSTI2017

Spherical Nanoindentation Stress-Strain Measurements of BOR-60 14YWT-NFA1 Irradiated Tubes

Spherical nanoindentation stress-strain protocols were applied to characterize unirradiated and fast neutron irradiated nanostructured ferritic alloy (NFA) 14YWT and compared against Berkovich nanohardness and available tensile data. The predicted uniaxial yield strength from spherical, 100 and 5 micron radii, indentation yield strength measurements was 1100-1400 MPa which compares well with the predictions from Berkovich nanohardness, 1200 MPa, and available tensile data, ~1100 MPa. However, spherical indentation measurements predict an increase in the uniaxial yield strength of ~1 GPa while Berkovich nanohardness measurements predict an increase of only ~250 MPa. No tensile data exists on the irradiated condition. It is believed the difference in the predicted uniaxial yield strength between spherical and Berkovich nanoindentation are due to a low number of tests on the irradiated sample combined with the significant heterogeneity in the microstructure, the differences in sensitivity to sample preparation on the irradiated sample between the two indentation protocols , and/or in how strain localizes under the indenter with the possibility of dislocation channeling under Berkovich hardness indents leading to strain softening. Nanoindentation capabilities to test neutron irradiated samples in a radiological area were realized.

36 MATERIALS SCIENCE↗
DOE OSTI2016

Biological Sampling Variability Study

There are many sources of variability that exist in the sample collection and analysis process. This paper addresses many, but not all, sources of variability. The main focus of this paper was to better understand and estimate variability due to differences between samplers. Variability between days was also studied, as well as random variability within each sampler. Experiments were performed using multiple surface materials (ceramic and stainless steel), multiple contaminant concentrations (10 spores and 100 spores), and with and without the presence of interfering material. All testing was done with sponge sticks using 10-inch by 10-inch coupons. Bacillus atrophaeus was used as the BA surrogate. Spores were deposited using wet deposition. Grime was coated on the coupons which were planned to include the interfering material (Section 3.3). Samples were prepared and analyzed at PNNL using CDC protocol (Section 3.4) and then cultured and counted. Five samplers were trained so that samples were taken using the same protocol. Each sampler randomly sampled eight coupons each day, four coupons with 10 spores deposited and four coupons with 100 spores deposited. Each day consisted of one material being tested. The clean samples (no interfering materials) were run first, followed by the dirty samples (coated with interfering material). There was a significant difference in recovery efficiency between the coupons with 10 spores deposited (mean of 48.9%) and those with 100 spores deposited (mean of 59.8%). There was no general significant difference between the clean and dirty (containing interfering material) coupons or between the two surface materials; however, there was a significant interaction between concentration amount and presence of interfering material. The recovery efficiency was close to the same for coupons with 10 spores deposited, but for the coupons with 100 spores deposited, the recovery efficiency for the dirty samples was significantly larger (65.9% - dirty vs. 53.6% - clean) (see Figure 4.1). Variance component analysis was used to estimate the amount of variability for each source of variability. There wasn’t much difference in variability for dirty and clean samples, as well as between materials, so these results were pooled together. There was a significant difference in amount of concentration deposited, so results were separated for the 10 spore and 100 spore deposited tests. In each case the within sampler variability was the largest with variances of 426.2 for 10 spores and 173.1 for 100 spores. The within sampler variability constitutes the variability between the four samples of similar material, interfering material, and concentration taken by each sampler. The between sampler variance was estimated to be 0 for 10 spores and 1.2 for 100 spores. The between day variance was estimated to be 42.1 for 10 spores and 78.9 for 100 spores. Standard deviations can be calculated in each case by taking the square root of the variance.

59 BASIC BIOLOGICAL SCIENCES↗
DOE OSTI2018

Dual-Readout Immunochromatographic Assay by Utilizing MnO 2 Nanoflowers as the Unique Colorimetric/Chemiluminescent Probe

Manganese dioxide nanoflowers (MnO2 NFs) were synthesized and utilized as a dual readout probe to develop a novel immunochromatographic test strip (ITS) for detecting pesticide residues using chlorpyrifos as the model analyte. MnO2 NFs-labeled antibody for chlorpyrifos was employed as the signal tracer for conducting the ITS. After 10-min competitive immunoreaction, the tracer antibody was captured by the immobilized immunogen on test line in the test strip, resulting in the accumulation of MnO2 NFs. The accumulation of MnO2 NFs led to the appearance of brown color on the test line, which could be easily observed by the naked eye as a qualitative readout. Moreover, MnO2 NFs showed a remarkably enhancing effect on the luminol-H2O2 chemiluminescent (CL) system. Unlike peroxidase-like nanomaterials, the enhancing mechanism of MnO2 NFs was based on its oxidant activity to decompose H2O2 for forming reactive oxygen species. After initiating the CL system in the test zone, strong CL signal was collected as a quantitative readout to sensitively detect chlorpyrifos. Under optimal conditions, the linear range of chlorpyrifos was 0.1–50 ng/mL with a low detection limit of 0.033 ng/mL (S/N = 3). The reliability of the dual-readout ITS was successfully demonstrated by the application on traditional Chinese medicine and environmental water samples. Due to the simultaneous rapid-qualitative and sensitive-quantitative detection, the dual-readout protocol provides a promising strategy for rapid screening and field assay on various areas such as environmental monitoring, food safety and point-of-care testing.

Ouyang, Hui↗
DOE OSTI2017

Analysis of Factors Affecting Successful Clinical Trial Enrollment in the Context of Three Prospective, Randomized, Controlled Trials

Purpose: Challenges can arise when attempting to maximize patient enrollment in clinical trials. There have been limited studies focusing on the barriers to enrollment and the efficacy of alternative study design to improve accrual. We analyzed barriers to clinical trial enrollment, particularly the influence of timing, in context of three prospective, randomized oncology trials where one arm was considered more aggressive than the other. Methods and Materials: From June 2011 to March 2015, patients who were enrolled on 3 prospective institutional protocols (an oligometastatic non-small cell lung cancer [NSCLC] trial and 2 proton vs intensity modulated radiation therapy trials in NSCLC and esophageal cancer) were screened for protocol eligibility. Eligible candidates were approached about trial participation, and patient characteristics (age, sex, T/N categorization) were recorded along with details surrounding trial presentation (appointment number). Fisher's exact test, Student's t tests, and multivariate analysis were performed to assess differences between enrolled and refusal patients. Results: A total of 309 eligible patients were approached about trial enrollment. The enrollment success rate during this time span was 52% (n=160 patients). Enrolled patients were more likely to be presented trial information at an earlier appointment (oligometastatic protocol: 5 vs 3 appointments [P<.001]; NSCLC protocol: 4 vs 3 appointments [P=.0018]; esophageal protocol: 3 vs 2 appointments [P=.0086]). No other factors or patient characteristics significantly affected enrollment success rate. Conclusion: Improvement in enrollment rates for randomized control trials is possible, even in difficult accrual settings. Earlier presentation of trial information to patients is the most influential factor for success and may help overcome accrual barriers without compromising trial design.

62 RADIOLOGY AND NUCLEAR MEDICINE↗