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NASA NTRS2003

Cardiovascular effects of anti-G suit and cooling garment during space shuttle re-entry and landing

BACKGROUND: Many cardiovascular changes associated with spaceflight reduce the ability of the cardiovascular system to oppose gravity on return to Earth, leaving astronauts susceptible to orthostatic hypotension during re-entry and landing. Consequently, an anti-G suit was developed to protect arterial pressure during re-entry. A liquid cooling garment (LCG) was then needed to alleviate the thermal stress resulting from use of the launch and entry suit. METHODS: We studied 34 astronauts on 22 flights (4-16 d). Subjects were studied 10 d before launch and on landing day. Preflight, crewmembers were suited with their anti-G suits set to the intended inflation for re-entry. Three consecutive measurements of heart rate and arterial pressure were obtained while seated and then again while standing. Three subjects who inflated the anti-G suits also donned the LCG for landing. Arterial pressure and heart rate were measured every 5 min during the de-orbit maneuver, through maximum G-loading (max-G) and touch down (TD). After TD, crew-members again initiated three seated measurements followed by three standing measurements. RESULTS: Astronauts with inflated anti-G suits had higher arterial pressure than those who did not have inflated anti-G suits during re-entry and landing (133.1 +/- 2.5/76.1 +/- 2.1 vs. 128.3 +/- 4.2/79.3 +/- 2.9, de-orbit; 157.3 +/- 4.5/102.1 +/- 3.6 vs. 145.2 +/- 10.5/95.7 + 5.5, max-G; 159.6 +/- 3.9/103.7 +/- 3.3 vs. 134.1 +/- 5.1/85.7 +/- 3.1, TD). In the group with inflated anti-G suits, those who also wore the LCG exhibited significantly lower heart rates than those who did not (75.7 +/- 11.5 vs. 86.5 +/- 6.2, de-orbit; 79.5 +/- 24.8 vs. 112.1 +/- 8.7, max-G; 84.7 +/- 8.0 vs. 110.5 +/- 7.9, TD). CONCLUSIONS: The anti-G suit is effective in supporting arterial pressure. The addition of the LCG lowers heart rate during re-entry.

NASA Center JSC↗
NASA NTRS2003

STS-114 Crew Training Clip

The crew of Space Shuttle Atlantis on STS-114 is seen conducting several training exercises in preparation for their mission. The crew consists of Commander Eileen Collins, Pilot James Kelly, and Mission Specialists Soichi Noguchi and Stephen Robinson. With them are Yuri Malenchenko, Sergei Moschenko, and Edward Lu, the intended Expedition 7 crew of the International Space Station (ISS). During extravehicular activity (EVA) training in the virtual reality (VR) laboratory, crew members explore the exterior of the ISS, seen on a monitor. Suiting up with VR equipment is also shown. More EVA training takes place in the Neutral Buoyancy Laboratory (NBL). Here the astronauts are suited up for the NBL pool, and lowered into the water on a platform. After a crew photo session, the astronauts are seated in the Motion Base Simulator in their flight suits. The simulator is shown rocking side-to-side. The crew also hears a hands-on explanation of EVA preparations in the ISS airlock, and practices emergency egress from the CCT, a simulator shaped like an orbiter.

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NASA NTRS2011

Preliminary Results of the Effect of Microgravity on Seated Height

The new vehicle for future space travel to the International Space Station (ISS) and beyond will be highly dependent on the seat layout. A primary concern with the seat layout design of the new vehicle is the amount of seated height growth that occurs in space; this could cause a major accommodation issue. The design of the seats, seat layout, suit fit, and crew accommodation are all critically affected due to the increase in height that occurs in microgravity. The increase in height due to spinal elongation caused by the absence of gravity could lead to inadequate clearances that would have implications for the ability of crewmembers to return safely or to conduct nominal operations during the mission. This study was designed to reduce the risk of inadequate design of the vehicle, environment, tools, equipment, etc. (SHFE risk 2.3.1.1) and safely return crewmembers to earth from low-earth orbit travel, ISS, and beyond. In order to safely return the crewmembers, the design requirements must anticipate microgravity growth, elongation of the spine, bone and muscle loss, fluid shifts, etc. Thus, this study is to determine the amount of torso growth (spinal elongation) for a seated posture during Shuttle and ISS missions. Crewmembers seated heights were collected before, during, and after spaceflight to quantify the amount of growth that occurred as a result of microgravity. The changes in seated height will provide the designers with a design requirement which allows for change in spinal growth for a seated posture. Preliminary results have shown that , during flight, seated height increases by a range of approximately 2-6 percent compared to pre-launch seated height.

Rajulu, Sudhakar↗
NASA NTRS2009

Preliminary Results of the Effect of Spinal Elongation in Microgravity on Seated Height

The Constellation Program is designing a new vehicle for future space travel to the International Space Station and to the Moon and beyond. One major accommodation and design issue that needs to be addressed with the current seat layout design is spinal elongation. Spinal elongation is the spinal growth that occurs due to straightening of the spinal curve and expansion of the inter-verbal discs in microgravity. Spinal elongation is critical to the design of the seats, seat layout, suit fit, and crew accommodation because of the implications it can have on the a safe return of the crewmembers or during the mission. Inadequate clearance between crewmembers and/or between crewmember hardware interfaces may potentially result in injury during the mission or upon returning to earth. Therefore, design requirements need to be determined that will allow for the elongation of the spine. The current requirement as specified in the Human Systems Integration Requirement (HSIR) document states that a 3% increase in standing height must be accommodated. However, it cannot be assumed that the amount of standing height growth is equivalent to the amount of spinal elongation because of the variation in body proportions between the lower body and torso. Thus, the purpose of this study was to determine the amount of spinal elongation for a seated posture for 6 Shuttle and 7 ISS missions. Crewmembers seated heights were collected before, during, and after spaceflight to determine the change in seated height and the amount of spinal growth that occurs due to microgravity. The changes in seated height will provide the designers with a design requirement that will allow for change in spinal growth for a seated posture. Preliminary results have shown that increase in seated height is greater than the 3% increase currently stated in the requirement.

Rajulu, Sudhakar↗
NASA NTRS2003

STS-113 Mission Highlights Resource Tape Flight Days 7-11. Tape: 3 of 4

This video, part 3 of 4, shows the activities of the crew of Space Shuttle Envdeavour and the Expedition 5 and 6 crews of the International Space Station (ISS) during flight days 7 through 11 of STS-113. Endeavour's crew consists of Commander Jim Wetherbee, Pilot Paul Lockhart, and Mission Specialists Michael Lopez-Alegria and John Herrington. Footage of flight day 7 includes a change of command ceremony on board the ISS, and Endeavour dumping supply water through a nozzle. On flight day 8 the Space Station Mobile Transporter jams while traveling on the P1 truss of the ISS, and Herrington attempts to free it as part of a lengthy extravehicular activity (EVA) with Lopez-Alegria. Flight day 9 is the last full day the three crews spend together. Expedition 5 NASA ISS Science Officer Peggy Whitsun troubleshoots the Microgravity Glovebox on board the ISS with her successor Don Pettit. The undocking of Endeavour and the ISS is the main activity of flight day 10. Endeavour also deploys a pair of experimental tethered microsatellites for the Department of Defense. The footage from flight day 11 shows the Expedition 5 crew exercising, laying in recumbant seats to help them adjust to the gravity on Earth, and sleeping. The video includes numerous views of the earth, some with the ISS and Endeavour in the foreground. There are close-ups of Italy, Spain and Portugal, Tierra del Fuego, and Baja California, and a night view of Chicago and the Great Lakes.

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NASA NTRS2008

Determining Exercise Strength Requirements for Astronaut Critical Mission Tasks: Reaching Under G-Load

The critical mission tasks assessments effort seeks to determine the physical performance requirements that astronauts must meet in order to safely and successfully accomplish lunar exploration missions. These assessments will determine astronaut preflight strength, fitness, and flexibility requirements, and the extent to which exercise and other countermeasures must prevent the physical deconditioning associated with prolonged weightlessness. The purpose is to determine the flexibility and strength that crewmembers must possess in order to reach Crew Exploration Vehicle controls during maneuvers that result in sustained acceleration levels ranging from 3.7G to 7.8G. An industry standard multibody dynamics application was used to create human models representing a 5th percentile female, a 50th percentile male, and a 95th percentile male. The additional mass of a space suit sleeve was added to the reaching arm to account for the influence of the suit mass on the reaching effort. The human model was merged with computer models of a pilot seat and control panel for the Crew Exploration Vehicle. Three dimensional paths were created that guided the human models hand from a starting position alongside its thigh to three control targets: a joystick, a keyboard, and an overhead switch panel. The reaching motion to each target was repeated under four vehicle acceleration conditions: nominal ascent (3.7G), two ascent aborts (5.5G and 7.8G) and lunar reentry (4.6G). Elbow and shoulder joint angular excursions were analyzed to assess range of motion requirements. Mean and peak elbow and shoulder joint torques were determined and converted to equivalent resistive exercise loads to assess strength requirements. Angular excursions for the 50th and 95th percentile male models remained within joint range of motion limits. For the 5th percentile female, both the elbow and the shoulder exceeded range of motion limits during the overhead reach. Elbow joint torques ranged from 10 N-m (nominal ascent) to 60 N-m (ascent abort). Shoulder joint torques ranged from 65 N-m (nominal ascent) to 280 N-m (ascent abort). Maximal equivalent exercise loads reached 30 lb in tricep extension, 9 lb in bicep curl, 110 lb in unilateral pullover and unilateral bench press for nominal conditions (lunar reentry), and 188 lb in unilateral pullover and unilateral bench press. The location of the pilot seat was found to be inadequately located to allow a 5th percentile female to reach the switches on the overhead panel. Elbow strength requirements were found to be well within population norms. Shoulder strength was found to be a limiting factor. Reaching under nominal ascent and lunar reentry conditions was found to require near maximal shoulder strength. Reaching under ascent abort conditions requires shoulder strength well beyond population norms. Pilot seats must adjust to accomodate a 5th percentile female. Exercise countermeasures must maintain maximal pullover and bench press strength to allow pilots to reach and operate controls during lunar reentry. Reaching will not be possible during ascent abort conditions. Flight controls should be built into armrests or flight control must be accomplished by autonomous systems during acceleration exceeding 4.6G.

Schaffner, Grant↗
NASA NTRS1985

Design and testing of an energy-absorbing crewseat for the F/FB-111 aircraft. Volume 2: Data from seat testing

The unacceptably high injury rate during the escape sequence (including the ejection and ground impact) of the crew module for F/FB-111 aircraft is reviewed. A program to determine if the injury potential could be reduced by replacing the existing crewseats with energy absorbing crewseats is presented. An energy absorbing test seat is designed using much of the existing seat hardware. An extensive dynamic seat test series, designed to duplicate various crew module ground impact conditions is conducted at a sled test facility. Comparative tests with operational F-111 crewseats are also conducted. After successful dynamic testing of the seat, more testing is conducted with the seats mounted in an F-111 crew module. Both swing tests and vertical drop tests are conducted. The vertical drop tests are used to obtain comparative data between the energy absorbing and operational seats. Volume 1 describes the energy absorbing test seat and testing conducted, and evaluates the data from both test series. Volume 2 presents the data obtained during the seat test series, while Volume 3 presents the data from the crew module test series.

Shane, S. J.↗
NASA NTRS2002

STS-113/Endeavour/ISS 11A Pre-Launch - Launch On Orbit - Landing - Crew Egress

The crew of STS-113 and the Expedition 6 crew of the International Space Station (ISS) are introduced leaving the suitup room and while being assisted in their seats onboard Space Shuttle Endeavour. The shuttle's crew consisted of Commander Jim Wetherbee, Pilot Paul Lockhart and Mission Specialists Michael Lopez-Alegria and John Herrington. The Expedition 6 crew consisted of Commander Ken Bowersox, Flight Engineer Nikolai Budarin and NASA ISS Science Officer Don Pettit. Clips of the Endeavour's night launch are shown from these cameras: Beach Tracker, VAB, Pad A, OTV-60, OTV-70, Tower 1, UCS-15, Press Site Grandstand, Cocoa Beach DOAMS, Playalinda Beach DOAMS, UCS-23, and the In-Cabin Camera. While on-orbit, highlights include the docking of Endeavour with the ISS, the Change of Command Ceremony by the Expedition 5 and 6 crews of the ISS, the mating of the P1 and S0 Trusses, and three extravehicular activities (EVAs) by astronauts Lopez-Allegria and Herrington. The shuttle crew also repairs a leak in the onboard Carbon Dioxide Removal Assembly. Clips of the shuttle's landing are shown from these cameras: VAB, Tower 1, Midfield, Runway South End, Runway North End, Tower 2, Playalinda DOAMS, UCS-3 Infrared, UCS-23, Midfield Infrared, and Pilot Point of View (PPOV).

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NASA NTRS2009

Development of a Methodology to Gather Seated Anthropometry in a Microgravity Environment

The Constellation Program's Crew Exploration Vehicle (CEV) is required to accommodate the full population range of crewmembers according to the anthropometry requirements stated in the Human-Systems Integration Requirement (HSIR) document (CxP70024). Seated height is one of many critical dimensions of importance to the CEV designers in determining the optimum seat configuration in the vehicle. Changes in seated height may have a large impact to the design, accommodation, and safety of the crewmembers. Seated height can change due to elongation of the spine when crewmembers are exposed to microgravity. Spinal elongation is the straightening of the natural curvature of the spine and the expansion of inter-vertebral disks. This straightening occurs due to fluid shifts in the body and the lack of compressive forces on the spinal vertebrae. Previous studies have shown that as the natural curvature of the spine straightens, an increase in overall height of 3% of stature occurs which has been the basis of the current HSIR requirements. However due to variations in the torso/leg ratio and impact of soft tissue, data is nonexistent as to how spinal elongation specifically affects the measurement of seated height. In order to obtain this data, an experiment was designed to collect spinal elongation data while in a seated posture in microgravity. The purpose of this study was to provide quantitative data that represents the amount of change that occurs in seated height due to spinal elongation in microgravity environments. Given the schedule and budget constraints of ISS and Shuttle missions and the uniqueness of the problem, a methodology had to be developed to ensure that the seated height measurements were accurately collected. Therefore, simulated microgravity evaluations were conducted to test the methodology and procedures of the experiment. This evaluation obtained seat pan pressure and seated height data to a) ensure that the lap restraint provided sufficient restraint to eliminate any gap between the subject s gluteal surface and the seat pan and b) to document any necessary design and procedural changes needed due to the microgravity environment. The methodology and setup used during the simulated microgravity evaluations was replicable to the proposed methodology and setup for in-space missions. A flight-like Shuttle seat, pressure sensors, anthropometer, and existing hardware was used to measure seated height and contact area while experiencing microgravity. The outlying buttock and thigh surface contact areas were collected to determine if the subjects were in contact with the seat pan, while a measurer recorded their seated height with an anthropometer. The Anthropometry and Biomechanics Facility (ABF) completed data collection from three microgravity flights to assess the restraint methods and techniques to be used for the in-flight procedures performed by the crewmembers in orbit. The first flight demonstrated that the restraint system on the seat, used in a nominal configuration, did not sufficiently restrain a person in the seat. The results showed the subjects were not in full contact with the seat pan, resulting in inaccurate sitting height data. Thus, a second flight was conducted to test different restraint system options. The results showed that by 1) changing the restraint system from the nominal 3-points of the 5-point harness, which is used for crewmembers when fully suited with emergency equipment, and 2) rerouting the lap straps around the joint of the backrest, where the backrest and seat pan are joined, resulted in the optimal method to restrain a subject. This rerouting method allowed for the anchor location to change and pull the subjects back into the seat instead of being anchored at the side of the subjects thighs. The results from the third flight validated the final restraint system, which resulted in a verified methodology for collecting seated anthropometry to ultimately determine the amount of spil elongation in a microgravity environment.

Rajulu, Sudhakar↗
NASA NTRS2003

STS-107 Crew Choice Television Highlights

The STS-107 flight day highlights begin with a shot inside the flight deck of the Space Shuttle Columbia where Commander Rick Husband, Pilot William McCool, and Mission Specialists David Brown and Kalpana Chawla are seated. The actual liftoff of the Space Shuttle Columbia is shown with Mission Specialists Michael Anderson and Laurel Clark, and Payload Specialist Ilan Ramon seated on the middeck of the spacecraft. Mission Specialist David Brown exits his seat to take pictures of the external tank while Michael Anderson also prepares to take photographs. A beautiful shot of the orbiter flying over Egypt is presented. A view of the Spacehab Research Double Module is shown where crystals are growing in microgravity. Laurel Clark is also shown working on the Bioreactor experiment. Michael Anderson is shown performing various breathing experiments in space. This video shows the last flight of STS-107 during ascent as the crew is seated in the flight deck and middeck of the Space Shuttle Columbia.

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NASA NTRS2009

Crashworthy Seats Would Afford Superior Protection

Seats to prevent or limit crash injuries to astronauts aboard the crew vehicle of the Orion spacecraft are undergoing development. The design of these seats incorporates and goes beyond crash-protection concepts embodied in prior spacecraft and racing-car seats to afford superior protection against impacts. Although the seats are designed to support astronauts in a recumbent, quasi-fetal posture that would likely not be suitable for non-spacecraft applications, parts of the design could be adapted to military and some civilian aircraft seats and to racing car seats to increase levels of protection. The main problem in designing any crashworthy seat is to provide full support of the occupant against anticipated crash and emergency-landing loads so as to safely limit motion, along any axis, of any part of the occupant s body relative to (1) any other part of the occupant s body, (2) the spacecraft or other vehicle, and (3) the seat itself. In the original Orion spacecraft application and in other applications that could easily be envisioned, the problem is complicated by severe limits on space available for the seat, a requirement to enable rapid egress by the occupant after a crash, and a requirement to provide for fitting of the seat to a wide range of sizes and shapes of a human body covered by a crash suit, space suit, or other protective garment. The problem is further complicated by other Orion-application-specific requirements that must be omitted here for the sake of brevity. To accommodate the wide range of crewmember body lengths within the limits on available space in the original Orion application, the design provides for taller crewmembers to pull their legs back closer toward their chests, while shorter crewmembers can allow their legs to stretch out further. The range of hip-support seat adjustments needed to effect this accommodation, as derived from NASA s Human Systems Integration Standard, was found to define a parabolic path along which the knees must be positioned. For a given occupant, the specific position along the path depends on the distance from the heel to the back of the knee. The application of the concept of parabolic adjustment of the hip-support structure caused the seat pan to also take on a parabolic shape, yielding the unanticipated additional benefit that the seat pan fits the occupant s buttocks and thighs more nearly conformally than do seat pans of prior design. This more nearly conformal fit effectively eliminates a void between the occupant s body and the seat pan, thereby helping to prevent what, in prior seat designs, was shifting of the occupant s body into that void during an impact.

Gohmert, Dustin↗
NASA NTRS2014

Validation of the 5th and 95th Percentile Hybrid III Anthropomorphic Test Device Finite Element Model

NASA spacecraft design requirements for occupant protection are a combination of the Brinkley criteria and injury metrics extracted from anthropomorphic test devices (ATD's). For the ATD injury metrics, the requirements specify the use of the 5th percentile female Hybrid III and the 95th percentile male Hybrid III. Furthermore, each of these ATD's is required to be fitted with an articulating pelvis and a straight spine. The articulating pelvis is necessary for the ATD to fit into spacecraft seats, while the straight spine is required as injury metrics for vertical accelerations are better defined for this configuration. The requirements require that physical testing be performed with both ATD's to demonstrate compliance. Before compliance testing can be conducted, extensive modeling and simulation are required to determine appropriate test conditions, simulate conditions not feasible for testing, and assess design features to better ensure compliance testing is successful. While finite element (FE) models are currently available for many of the physical ATD's, currently there are no complete models for either the 5th percentile female or the 95th percentile male Hybrid III with a straight spine and articulating pelvis. The purpose of this work is to assess the accuracy of the existing Livermore Software Technology Corporation's FE models of the 5th and 95th percentile ATD's. To perform this assessment, a series of tests will be performed at Wright Patterson Air Force Research Lab using their horizontal impact accelerator sled test facility. The ATD's will be placed in the Orion seat with a modified-advanced-crew-escape-system (MACES) pressure suit and helmet, and driven with loadings similar to what is expected for the actual Orion vehicle during landing, launch abort, and chute deployment. Test data will be compared to analytical predictions and modelling uncertainty factors will be determined for each injury metric. Additionally, the test data will be used to further improve the FE model, particularly in the areas of the ATD neck components, harness, and suit and helmet effects.

Lawrence, C.↗
NASA NTRS2021

Functional Task Tests in Partial Gravity during Parabolic Flight

Critical mission tasks that are required by crews immediately after landing on a planetary surface are seat egress, jump, and walk. To be able to define an effective and comprehensive countermeasure strategy for preserving crew performance during exploration-class missions, there is a need to understand how these functional tasks are actually performed in partial gravity such as on the Moon or Mars. We propose to study the performance of the execution of these tasks during partial gravity phases (0.25g, 0.5g, 0.75g) of parabolic flight.

Gilles R Clement↗
NASA NTRSDate not supplied

Functional Task Tests in Partial Gravity During Parabolic Flight

BACKGROUND Critical mission tasks that are required by crews immediately after landing on a planetary surface are seat egress, jump, and walk. To be able to define an effective and comprehensive countermeasure strategy for preserving crew performance during exploration-class missions, there is a need to understand how these functional tasks are actually performed in partial gravity such as on the Moon or Mars. We propose to study the performance in the execution of these tasks during the partial gravity and hypergravity phases of parabolic flight. These tasks will be completed using the same equipment and procedures as the Standard Measures Sensorimotor protocol, which is performed by astronauts returning from spaceflight and by ground-based subjects after prolonged axial body unloading during bed rest. HYPOTHESIS We hypothesize that partial gravity during parabolic flight will cause acute changes in vestibular, proprioceptive, and sensorimotor functions, and these changes will impact the performance of mission critical tasks such as standing, walking, and jumping. The largest changes in performance are expected at the lowest gravity level (0.25g) because subjects will no longer be able to use the gravitational reference for the perception of vertical. Ultimately, this information could be used to assess performance risks and inform the design of countermeasures for NASA exploration-class human missions. METHODS Twelve subjects will be tested during three flights of 30 parabolas, including 10 parabolas at 0.25g, 10 parabolas at 0.5g and 10 parabolas at 0.75g. Subject also will perform tests in 1g between parabolas and in hypergravity (1.8g) during the pull-out phases. Subjects will perform the same tasks as those tested on astronauts returning from spaceflight: sit-to-stand and obstacle walk, tandem walk, jump down, and recovery from fall. Measurements will include: (a) the time for the subject to complete the test (sit-to-stand and obstacle walk, recovery from fall); (b) the time elapsed between the start of motion and the stabilization of upright posture (recovery from fall, jump down); (c) the mean sway speed during quiet standing (recovery from fall, jump down); (d) changes in heart rate and blood pressure (recovery from fall); (e) the percentage of correct steps and torso acceleration (tandem walk); and (f) the severity of motion sickness symptoms. RELEVANCE Although gravitational dose-response curves have been obtained for some biochemical systems in animals, these dose-responses are unknown for most human physiologic systems. Our study will compare the outcomes of 5 functional task tests in 0.25g, 0.5g, 0.75g, 1g, and 1.8g with those previously obtained in ground-based subjects after prolonged axial body unloading and in astronauts immediately after spaceflight. This comparison will help understanding the true extent of functional task performance deficits in partial gravity. The dose-response relationship between gravity level and task performance decrement also will help determining the gravity threshold for these functional tasks. ACKNOWLEDGEMENT This work is supported by the NASA’s Human Research Program Human Health Countermeasures Element

Gilles Clement↗
NASA NTRS2008

Composite shell spacecraft seat

A two-part seat (10) providing full body support that is specific for each crew member (30) on an individual basis. The two-part construction for the seat (10) can accommodate many sizes and shapes for crewmembers (30) because it is reconfigurable and therefore reusable for subsequent flights. The first component of the two-part seat construction is a composite shell (12) that surrounds the crewmember's entire body and is generically fitted to their general size in height and weight. The second component of the two-part seat (10) is a cushion (20) that conforms exactly to the specific crewmember's entire body and gives total body support in more complex environment.

Barackman, Victor J.↗
NASA NTRS2022

Changes in Optic Nerve Head and Retinal Morphology During Spaceflight and Acute Fluid Shift Reversal

Importance: Countermeasures that reverse the headward fluid shift experienced in weightlessness have the potential to mitigate spaceflight-associated neuro-ocular syndrome. This study investigated whether use of the countermeasure lower-body negative pressure during spaceflight was associated with changes in ocular structure. Objective: To determine whether changes to the optic nerve head and retina during spaceflight can be mitigated by brief in-flight application of 25-mm Hg lower-body negative pressure. Design, Setting, and Participants: In the National Aeronautics and Space Administration’s “Fluid Shifts Study,” a prospective cohort study, optical coherence tomography scans of the optic nerve head and macula were obtained from US and international crew members before flight, in-flight, and up to 180 days after return to Earth. In-flight scans were obtained both under normal weightless conditions and 10 to 20 minutes into lower-body negative pressure exposure. Preflight and postflight data were collected in the seated, supine, and head-down tilt postures. Crew members completed 6- to 12-month missions that took place on the International Space Station. Data were analyzed from 2016 to 2021. Interventions or Exposures: Spaceflight and lower-body negative pressure. Main Outcomes and Measures: Changes in minimum rim width, optic cup volume, Bruch membrane opening height, peripapillary total retinal thickness, and macular thickness. Results: Mean (SD) flight duration for the 14 crew members (mean [SD] age, 45 [6] years; 11 male crew members [79%]) was 214 (72) days. Ocular changes on flight day 150, as compared with preflight seated, included an increase in minimum rim width (33.8 μm; 95% CI, 27.9-39.7 μm; P < .001), decrease in cup volume (0.038 mm^3; 95% CI, 0.030-0.046 mm^3; P < .001), posterior displacement of Bruch membrane opening (−9.0 μm; 95% CI, −15.7 to −2.2 μm; P = .009), and decrease in macular thickness (fovea to 500 μm, 5.1 μm; 95% CI, 3.5-6.8 μm; P < .001). Brief exposure to lower-body negative pressure did not affect these parameters. Conclusions and Relevance: Results of this cohort study suggest that peripapillary tissue thickening, decreased cup volume, and mild central macular thinning were associated with long-duration spaceflight. Acute exposure to 25-mm Hg lower-body negative pressure did not alter optic nerve head or retinal morphology, suggesting that longer durations of a fluid shift reversal may be needed to mitigate spaceflight-induced changes and/or other factors are involved.

Laura P. Pardon↗
NASA NTRS2011

NASA Occupant Protection Standards Development

Current National Aeronautics and Space Administration (NASA) occupant protection standards and requirements are based on extrapolations of biodynamic models, which were based on human tests performed under pre-Space Shuttle human flight programs where the occupants were in different suit and seat configurations than is expected for the Multi Purpose Crew Vehicle (MPCV) and Commercial Crew programs. As a result, there is limited statistical validity to the occupant protection standards. Furthermore, the current standards and requirements have not been validated in relevant spaceflight suit, seat configurations or loading conditions. The objectives of this study were to develop new standards and requirements for occupant protection and rigorously validate these new standards with sub-injurious human testing. To accomplish these objectives we began by determining which critical injuries NASA would like to protect for. We then defined the anthropomorphic test device (ATD) and the associated injury metrics of interest. Finally, we conducted a literature review of available data for the Test Device for Human Occupant Restraint New Technology (THOR-NT) ATD to determine injury assessment reference values (IARV) to serve as a baseline for further development. To better understand NASA s environment, we propose conducting sub-injurious human testing in spaceflight seat and suit configurations with spaceflight dynamic loads, with a sufficiently high number of subjects to validate no injury during nominal landing loads. In addition to validate nominal loads, the THOR-NT ATD will be tested in the same conditions as the human volunteers, allowing correlation between human and ATD responses covering the Orion nominal landing environment and commercial vehicle expected nominal environments. All testing will be conducted without the suit and with the suit to ascertain the contribution of the suit to human and ATD responses. In addition to the testing campaign proposed, additional data analysis is proposed to mine existing human injury and response data from other sources, including military volunteer testing, automotive Crash Injury Research Engineering Network (CIREN), and IndyCar impact and injury data. These data sources can allow a better extrapolation of the ATD responses to off-nominal conditions above the nominal range that can safely be tested. These elements will be used to develop injury risk functions for each of the injury metrics measured from the ATD. These risk functions would serve as the basis for the NASA standards. Finally, we propose defining standard test methodology for evaluating future spacecraft designs against the IARVs, including developing a star-rating system to allow crew safety comparisons between vehicles.

Somers, Jeffrey T.↗
NASA NTRS2000

STS-99 Crew Activities Report/Flight Day 1 Highlights

Live footage shows the crew, Commander Kevin R. Kregel, Pilot Dominic L. Pudwill Gorie, and Mission Specialists Janet L. Kavandi, Janice E. Voss, Mamoru Mohri and Gerhard P.J. Thiele, seated in the dining room with the traditional cake. The crew is seen performing various pre-launch activities including suit-up, walk out to the Astro-van, and strap-in into the vehicle. Also seen are the retractions of the orbiter access arm and the gaseous oxygen mint hood, main engine start, booster ignition, liftoff, and separation of the solid rocket boosters. The Red Team (first of the dual shift crew) includes Kregel, Kavandi, and Thiele, who are shown conducting jet thruster firings, activating radar instruments, and deploying the boom (mass).

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