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NASA's Human Research Program: Addressing Challenges to Human Health and Performance
The presentation discusses the general, potential health effects of long term space flight on crew. It discusses some examples of unique hazards and health risk causes, brief examples of effects, and an introduction on NASA programs to study and mitigate the harms.
Monitoring Human Health and Performance using Body-worn Motion Sensors
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Minimizing Human Risk: Human Performance Models in the Space Human Factors and Habitability and Behavioral Health and Performance Elements
Human space exploration has never been more exciting than it is today. Human presence to outer worlds is becoming a reality as humans are leveraging much of our prior knowledge to the new mission of going to Mars. Exploring the solar system at greater distances from Earth than ever before will possess some unique challenges, which can be overcome thanks to the advances in modeling and simulation technologies. The National Aeronautics and Space Administration (NASA) is at the forefront of exploring our solar system. NASA's Human Research Program (HRP) focuses on discovering the best methods and technologies that support safe and productive human space travel in the extreme and harsh space environment. HRP uses various methods and approaches to answer questions about the impact of long duration missions on the human in space including: gravity's impact on the human body, isolation and confinement on the human, hostile environments impact on the human, space radiation, and how the distance is likely to impact the human. Predictive models are included in the HRP research portfolio as these models provide valuable insights into human-system operations. This paper will provide an overview of NASA's HRP and will present a number of projects that have used modeling and simulation to provide insights into human-system issues (e.g. automation, habitat design, schedules) in anticipation of space exploration.
Medical Support for ISS Crewmember Training in Star City, Russia
Medical support of spaceflight training operations across international lines is a unique circumstance with potential applications to other aerospace medicine support scenarios. KBRwyle's Star City Medical Support Group (SCMSG) has fulfilled this role since the Mir-Shuttle era, with extensive experience and updates to share with the greater AsMA community. OVERVIEW: The current Soyuz training flow for assigned ISS crewmembers takes place in Star City, Russia. Soyuz training flow involves numerous activities that pose potential physical and occupational risks to crewmembers, including centrifuge runs and pressurized suit simulations at ambient and hypobaric pressures. In addition, Star City is a relatively remote location in a host nation with variable access to reliable, Western-standard medical care. For these reasons, NASA's Human Health & Performance contract allocates full-time physician support to assigned ISS crewmembers training in Star City. The Star City physician also treats minor injuries and illnesses as needed for both long- and short-term NASA support personnel traveling in the area, while working to develop and maintain relationships with local health care resources in the event of more serious medical issues that cannot be treated on-site. The specifics of this unique scope of practice will be discussed. SIGNIFICANCE: ISS crewmembers training in Star City are at potential physical and occupational risk of trauma or dysbarism during nominal Soyuz training flow, requiring medical support from an on-duty aerospace medicine specialist. This support maintains human health and performance by preserving crewmember safety and well-being for mission success; sharing information regarding this operational model may contribute to advances in other areas of international, military, and civilian operational aerospace medicine.
Medical Support for ISS Crewmember Training in Star City, Russia
Medical support of spaceflight training operations across international lines is a unique circumstance with potential applications to other aerospace medicine support scenarios. KBRwyle's Star City Medical Support Group (SCMSG) has fulfilled this role since the Mir-Shuttle era, with extensive experience and updates to share with the greater AsMA community. OVERVIEW: The current Soyuz training flow for assigned ISS crewmembers takes place in Star City, Russia. Soyuz training flow involves numerous activities that pose potential physical and occupational risks to crewmembers, including centrifuge runs and pressurized suit simulations at ambient and hypobaric pressures. In addition, Star City is a relatively remote location in a host nation with variable access to reliable, Western-standard medical care. For these reasons, NASA's Human Health & Performance contract allocates full-time physician support to assigned ISS crewmembers training in Star City. The Star City physician also treats minor injuries and illnesses as needed for both long- and short-term NASA support personnel traveling in the area, while working to develop and maintain relationships with local health care resources in the event of more serious medical issues that cannot be treated on-site. The specifics of this unique scope of practice will be discussed. SIGNIFICANCE: ISS crewmembers training in Star City are at potential physical and occupational risk of trauma or dysbarism during nominal Soyuz training flow, requiring medical support from an on-duty aerospace medicine specialist. This support maintains human health and performance by preserving crewmember safety and well-being for mission success; sharing information regarding this operational model may contribute to advances in other areas of international, military, and civilian operational aerospace medicine.
Space Mission Human Reliability Analysis (HRA) Project
The purpose of the Space Mission Human Reliability Analysis (HRA) Project is to extend current ground-based HRA risk prediction techniques to a long-duration, space-based tool. Ground-based HRA methodology has been shown to be a reasonable tool for short-duration space missions, such as Space Shuttle and lunar fly-bys. However, longer-duration deep-space missions, such as asteroid and Mars missions, will require the crew to be in space for as long as 400 to 900 day missions with periods of extended autonomy and self-sufficiency. Current indications show higher risk due to fatigue, physiological effects due to extended low gravity environments, and others, may impact HRA predictions. For this project, Safety & Mission Assurance (S&MA) will work with Human Health & Performance (HH&P) to establish what is currently used to assess human reliabiilty for human space programs, identify human performance factors that may be sensitive to long duration space flight, collect available historical data, and update current tools to account for performance shaping factors believed to be important to such missions. This effort will also contribute data to the Human Performance Data Repository and influence the Space Human Factors Engineering research risks and gaps (part of the HRP Program). An accurate risk predictor mitigates Loss of Crew (LOC) and Loss of Mission (LOM).The end result will be an updated HRA model that can effectively predict risk on long-duration missions.
IMPACT Concept of Operations
NASA’s future exploration missions mandate a significant paradigm change for mission planning, spacecraft design, human systems integration, and in-flight medical care due to constraints on mass, volume, power, resupply missions, and medical evacuation capabilities. These constraints require further development of the human health and performance system, which includes the medical, task performance, wellness, data, human and other systems necessary to keep the crew healthy and functioning optimally. The human health and performance system will be tightly integrated with mission and habitat design to provide a sufficient human health and performance infrastructure to enable mission success. A suite of systems engineering tools will aid in the decision making process for the development of such a human health and performance system. This Concept of Operations provides a vision for a tool suite to conduct evaluations of human health and performance system options, inform research prioritization, and provide trade study support, based on evidence, risks, and systems engineering principles. The integrated tool suite under development is IMPACT.
Fall 2015 NASA Internship, and Space Radiation Health Project
This fall, I was fortunate enough to have been able to participate in an internship at NASA's Lyndon B. Johnson Space Center. I was placed into the Human Health & Performance Directorate, where I was specifically tasked to work with Dr. Zarana Patel, researching the impacts of cosmic level radiation on human cells. Using different laboratory techniques, we were able to examine the cells to see if any damage had been done due to radiation exposure, and if so, how much damage was done. Cell culture samples were exposed at different doses, and fixed at different time points so that we could accumulate a large pool of quantifiable data. After examining quantifiable results relative to the impacts of space radiation on the human body at the cellular and chromosomal level, researchers can defer to different areas of the space program that have to do with astronaut safety, and research and development (extravehicular mobility unit construction, vehicle design and construction, etc.). This experience has been very eye-opening, and I was able to learn quite a bit. I learned some new laboratory techniques, and I did my best to try and learn new ways to balance such a hectic work and school schedule. I also learned some very intimate thing about working at NASA; I learned that far more people want to watch you succeed, rather than watch you fail, and I also learned that this is a place that is alive with innovators and explorers - people who have a sole purpose of exploring space for the betterment of humanity, and not for any other reason. It's truly inspiring. All of these experiences during my internship have impacted me in a really profound way, so much that my educational and career goals are completely different than when I started. I started out as a biotechnology major, and I discovered recently toward the end of the internship, that I don't want to work in a lab, nor was I as enthralled by biological life sciences as a believed myself to be. Taking that all into consideration, I've actually changed my major to mechanical engineering. I discovered that I enjoy building things, and I enjoy learning about materials and interactions between different things. And I quickly became obsessed with rocket and aerospace engineering, so I've decided that after a mechanical engineering degree, I will be pursuing an advanced degree in aerospace engineering. One final way that I was effected by this internship, is that I discovered that I don't want to have a career at NASA. I love this agency with all of my heart, but I refuse to allow my innovation to be bound by a scientifically illiterate congress. As such, I have decided to pursue commercial aerospace companies, such as Space, XCOR, Masten Space Systems, Orbital ATK, and many, many, more. Maybe one day I'll end up back here. I believe in what this agency is doing with my whole heart, and it's unfortunate to see them curtailed in some capacities as a result of budgetary constraints, brought on by people who don't fully understand the effort behind putting people in to space. All in all, this experience has been the best experience of my life - literally a childhood dream came true during this experience - and I cannot adequately explain how grateful I am to have been here for the past sixteen weeks.
Performance Characterization of a Prototype Ultra-Short Channel Monolith Catalytic Reactor for Air Quality Control Applications
Contaminated air and process gases, whether in a crewed spacecraft cabin atmosphere, the working volume of a microgravity science or ground-based laboratory experiment facility, or the exhaust from an automobile, are pervasive problems that ultimately effect human health, performance, and well-being. The need for highly-effective, economical decontamination processes spans a wide range of terrestrial and space flight applications. Adsorption processes are used widely for process gas decontamination. Most industrial packed bed adsorption processes use activated carbon because it is cheap and highly effective. Once saturated, however, the adsorbent is a concentrated source of contaminants. Industrial applications either dump or regenerate the activated carbon. Regeneration may be accomplished in-situ or at an off-site location. In either case, concentrated contaminated waste streams must be handled appropriately to minimize environmental impact. As economic and regulatory forces drive toward minimizing waste and environmental impact, thermal catalytic oxidation is becoming more attractive. Through novel reactor and catalyst design, more complete contaminant destruction and greater resistance to poisoning can achieved leading to less waste handling, process down-time, and maintenance. Performance of a prototype thermal catalytic reactor, based on ultra-short channel monolith (USCM) catalyst substrate design, under a variety of process flow and contaminant loading conditions is discussed. The experimental results are evaluated against present and future air quality control and process gas purification processes used on board crewed spacecraft.
JETT3: A Holistic, Integrated Analog for Artemis Lunar Surface Exploration
Since 1972, NASA astronauts have performed hundreds of Extravehicular Activities (EVAs) in support of Skylab, Space Shuttle and International Space Station missions. Not since Apollo, however, have EVAs been driven by discovery-based principles of scientific exploration. Upcoming Artemis missions are challenged to build on lessons learned from Apollo, merging 50 years of EVA experience with the planetary science community’s expertise in the remote surface exploration of Mars. The highest-fidelity preparation for Artemis includes both operational and scientific underpinning to represent the complete, complex picture of lunar surface operations. The Joint EVA & Human Surface Mobility Test Team (JETT) is an interdisciplinary team providing such an environment for collaborative analog testing. JETT builds upon prior analog campaigns (e.g., [1, 2]) to provide high-fidelity environments for hardware and concept of operations development. Sponsored by the NASA EVA & Human Surface Mobility Program (EHP), JETT includes representatives from EHP, NASA Engineering, the Science Mission Directorate (SMD), Human Health & Performance, and the Flight Operations Directorate (FOD). JETT tests evaluate NASA reference designs for EVA (e.g., suits and tools), address gaps and risks for Artemis lunar surface operations, develop capabilities for EVA and science tasks, enable technology maturation, and provide training for Artemis EVA operations. JETT3, the final JETT field test of FY22, occurred Oct 3-11, 2022 in the San Francisco Volcanic Field north of Flagstaff, AZ. The test focused on developing the Artemis concept of operations and systems, including integrating an Artemis-like Science Team into a NASA Flight Control Team (FCT) to plan and execute a series of simulated lunar EVAs in an environment analogous to Artemis 3.
JETT3: A Holistic, Integrated Analog for Artemis Lunar Surface Exploration
Since 1972, NASA astronauts have performed hundreds of Extravehicular Activities (EVAs) in support of Skylab, Space Shuttle and International Space Station missions. Not since Apollo, however, have EVAs been driven by discovery-based principles of scientific exploration. Upcoming Artemis missions are challenged to build on lessons learned from Apollo, merging 50 years of EVA experience with the planetary science community’s expertise in the remote surface exploration of Mars. The highest-fidelity preparation for Artemis includes both operational and scientific underpinning to represent the complete, complex picture of lunar surface operations. The Joint EVA & Human Surface Mobility Test Team (JETT) is an interdisciplinary team providing such an environment for collaborative analog testing. JETT builds upon prior analog campaigns (e.g., [1, 2]) to provide high-fidelity environments for hardware and concept of operations development. Sponsored by the NASA EVA & Human Surface Mobility Program (EHP), JETT includes representatives from EHP, NASA Engineering, the Science Mission Directorate (SMD), Human Health & Performance, and the Flight Operations Directorate (FOD). JETT tests evaluate NASA reference designs for EVA (e.g., suits and tools), address gaps and risks for Artemis lunar surface operations, develop capabilities for EVA and science tasks, enable technology maturation, and provide training for Artemis EVA operations. JETT3, the final JETT field test of FY22, occurred Oct 3-11, 2022 in the San Francisco Volcanic Field north of Flagstaff, AZ. The test focused on developing the Artemis concept of operations and systems, including integrating an Artemis-like Science Team into a NASA Flight Control Team (FCT) to plan and execute a series of simulated lunar EVAs in an environment analogous to Artemis 3.
Thermal Catalytic Oxidation of Airborne Contaminants by a Reactor Using Ultra-Short Channel Length, Monolithic Catalyst Substrates
Contaminated air, whether in a crewed spacecraft cabin or terrestrial work and living spaces, is a pervasive problem affecting human health, performance, and well being. The need for highly effective, economical air quality processes spans a wide range of terrestrial and space flight applications. Typically, air quality control processes rely on absorption-based processes. Most industrial packed-bed adsorption processes use activated carbon. Once saturated, the carbon is either dumped or regenerated. In either case, the dumped carbon and concentrated waste streams constitute a hazardous waste that must be handled safely while minimizing environmental impact. Thermal catalytic oxidation processes designed to address waste handling issues are moving to the forefront of cleaner air quality control and process gas decontamination processes. Careful consideration in designing the catalyst substrate and reactor can lead to more complete contaminant destruction and poisoning resistance. Maintenance improvements leading to reduced waste handling and process downtime can also be realized. Performance of a prototype thermal catalytic reaction based on ultra-short waste channel, monolith catalyst substrate design, under a variety of process flow and contaminant loading conditions, is discussed.
Updates and Overview of Spaceflight Medical Support in Russia and Kazakhstan
This panel presents recent updates to and a comprehensive overview of the operational medical support provided to ISS crewmembers in Star City, Russia and Kazakhstan as part of UTMB/KBRwyle's Human Health & Performance contract. With the current Soyuz training flow, physician support is required for nominal training evolutions involving pressure changes or other potential physical risks detailed in this presentation. In addition, full-time physician presence in Star City helps to address the disparity in access to health care in these relatively remote practice areas, while also developing and maintaining relationships with host nation resources. A unique part of standard training in Russia also involves survival training in both winter and water environments; logistic details and medical impacts of each of these training scenarios will be discussed. Following support of a successful training flow, UTMB/KBRwyle's Star City Medical Support Group (SCMSG) is also responsible for configuring medical packs in support of Soyuz launches and landings; we will present the rationale for current pack contents within the context of specific operational needs. With respect to contingency events, the group will describe their preparedness to respond appropriately by activating both local and global resources as necessary, detailing a specialized subset of the group who continually work and update these assets, given changes in international infrastructure and other impacts.
The Integration of Life Sciences in Space: Astrobiology and Space Biology Virtual Workshops Report
A series of virtual workshops was held during June 2020 to seek ways to integrate the efforts of the astrobiology and space biology research communities under a broad umbrella of space life sciences. The overall goal was to help inspire creativity that will guide us towards new synergistic ideas complementing these existing disciplines that are of such importance to NASA. Workshop participants aspired to: (1) Exploit synergies across the biological sciences at NASA, (2) Foster research, enabling technology, and mission concepts that support commonalities in space biology, astrobiology, synthetic biology, planetary protection, and relevant human health, performance, and habitation concerns, (3) Envision the development of an “Arc of Biology in Space” to encompass this multi-faceted joint research community. The focused objective of the workshop series was to explore and demonstrate how the integration of astrobiology and space biology could be achieved, identify strengths and weaknesses in the current state of the art, and recognize where our greatest challenges lay. Specifically, we seek to: (1) Establish a scientific framework for an integrated life sciences effort, (2) Pioneer discovery by creating unique opportunities in the fundamental biological sciences, (3) Explore novel combinations of existing technologies across the relevant disciplines, (4) Invent new technologies and applications in space life sciences, and (5) Creatively increase access to spaceflight, emerging and novel technologies, Earth analogs, and simulated natural and spaceflight environments. The community aims for a broad arc of biological competence in the context of space and planetary science, spaceflight, and habitation. We will present dominant themes and innovative ideas that resulted from this interchange of relevant communities.
The Integration of Life Sciences in Space: Astrobiology and Space Biology Virtual Workshops Report
A series of virtual workshops was held during June 2020 to seek ways to integrate the efforts of the astrobiology and space biology research communities under a broad umbrella of space life sciences. The overall goal was to help inspire creativity that will guide us towards new synergistic ideas complementing these existing disciplines that are of such importance to NASA. Workshop participants aspired to: (1) Exploit synergies across the biological sciences at NASA, (2) Foster research, enabling technology, and mission concepts that support commonalities in space biology, astrobiology, synthetic biology, planetary protection, and relevant human health, performance, and habitation concerns, (3) Envision the development of an “Arc of Biology in Space” to encompass this multi-faceted joint research community. The focused objective of the workshop series was to explore and demonstrate how the integration of astrobiology and space biology could be achieved, identify strengths and weaknesses in the current state of the art, and recognize where our greatest challenges lay. Specifically, we seek to: (1) Establish a scientific framework for an integrated life sciences effort, (2) Pioneer discovery by creating unique opportunities in the fundamental biological sciences, (3) Explore novel combinations of existing technologies across the relevant disciplines, (4) Invent new technologies and applications in space life sciences, and (5) Creatively increase access to spaceflight, emerging and novel technologies, Earth analogs, and simulated natural and spaceflight environments. The community aims for a broad arc of biological competence in the context of space and planetary science, spaceflight, and habitation. We will present dominant themes and innovative ideas that resulted from this interchange of relevant communities.
Considerations for Health and Performance During Surface Extravehicular Activities
BACKGROUND: NASA’s objectives for expanding human presence beyond low Earth orbit will require Extravehicular Activities (EVAs) on lunar and planetary surfaces. Given the physiological and functional demands of conducting surface EVAs in a pressurized spacesuit in reduced gravity environments, there is a possibility that crew injury and compromised physiological and/or functional performance may present. OVERVIEW: Many human health and performance knowledge gaps exist in regards to exploration EVA that require characterization to ensure safety, reliability, and mission success. To address knowledge gaps, EVA simulations in Earth-based analog environments and/or spacesuit simulators can be utilized to provide valuable insights into task-based physiologic and metabolic costs, cognitive loads, and associated operational limitations to inform future mission concepts. Physical workloads approaching 60% of maximum metabolic rates and 85% age-predicted heart rate maxima; core body temperatures approaching 100o F; and subjective responses indicating limited spare cognitive capacity via Bedford scale have been observed during ground-based exploration EVA simulations in the NASA Active Response Gravity Offload Simulator (ARGOS) and Neutral Buoyancy Lab (NBL) during simulated planetary EVAs in pressurized suits. Further, ground-based EVA analogs vary in their ability to simulate planetary EVA and resulting physical workloads. DISCUSSION: Metabolic costs, thermal burdens, functional strength, and cognitive impacts have been and must continue to be assessed in ground-based analogs to fully characterize operational demands and crew readiness levels for exploration EVA. Considerations should be given to enabling a new concept of high-tempo surface EVA operations and associated work-rest intervals, understanding human health and performance impacts of evolving commercial suit designs and capabilities, and predictive modeling and decision support capabilities to enable safe and successful EVA operations.
Considerations for Health and Performance during Surface Extravehicular Activities
BACKGROUND: NASA’s objectives for expanding human presence beyond low Earth orbit will require Extravehicular Activities (EVAs) on lunar and planetary surfaces. Given the physiological and functional demands of conducting surface EVAs in a pressurized spacesuit in reduced gravity environments, there is a possibility that crew injury and compromised physiological and/or functional performance may present. OVERVIEW: Many human health and performance knowledge gaps exist in regards to exploration EVA that require characterization to ensure safety, reliability, and mission success. To address knowledge gaps, EVA simulations in Earth-based analog environments and/or spacesuit simulators can be utilized to provide valuable insights into task-based physiologic and metabolic costs, cognitive loads, and associated operational limitations to inform future mission concepts. Physical workloads approaching 60% of maximum metabolic rates and 85% age-predicted heart rate maxima; core body temperatures approaching 100° F; and subjective responses indicating limited spare cognitive capacity via Bedford scale have been observed during ground-based exploration EVA simulations in the NASA Active Response Gravity Offload Simulator (ARGOS) and Neutral Buoyancy Lab (NBL) during simulated planetary EVAs in pressurized suits. Further, ground-based EVA analogs vary in their ability to simulate planetary EVA and resulting physical workloads. DISCUSSION: Metabolic costs, thermal burdens, functional strength, and cognitive impacts have been and must continue to be assessed in ground-based analogs to fully characterize operational demands and crew readiness levels for exploration EVA. Considerations should be given to enabling a new concept of high-tempo surface EVA operations and associated work-rest intervals, understanding human health and performance impacts of evolving commercial suit designs and capabilities, and predictive modeling and decision support capabilities to enable safe and successful EVA operations.