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At least 55 records · Page 3

ON THE ROLE OF INVOLUTIONS IN THE DISCONTINUOUS GALERKIN DISCRETIZATION OF MAXWELL AND MAGNETOHYDRODYNAMIC SYSTEMS

The role of involutions in energy stability of the discontinuous Galerkin (DG) discretization of Maxwell and magnetohydrodynamic (MHD) systems is examined. Important differences are identified in the symmetrization of the Maxwell and MHD systems that impact the construction of energy stable discretizations using the DG method. Specifically, general sufficient conditions to be imposed on the DG numerical flux and approximation space are given so that energy stability is retained These sufficient conditions reveal the favorable energy consequence of imposing continuity in the normal component of the magnetic induction field at interelement boundaries for MHD discretizations. Counterintuitively, this condition is not required for stability of Maxwell discretizations using the discontinuous Galerkin method.

Barth, Timothy↗

A Microfabricated Segmented-Involute-Foil Regenerator for Enhancing Reliability and Performance of Stirling Engines

An actual-size microfabricated regenerator comprised of a stack of 42 disks, 19 mm diameter and 0.25 mm thick, with layers of microscopic, segmented, involute-shaped flow channels was fabricated and tested. The geometry resembles layers of uniformly-spaced segmented-parallel-plates, except the plates are curved. Each disk was made from electro-plated nickel using the LiGA process. This regenerator had feature sizes close to those required for an actual Stirling engine but the overall regenerator dimensions were sized for the NASA/Sunpower oscillating-flow regenerator test rig. Testing in the oscillating-flow test rig showed the regenerator performed extremely well, significantly better than currently used random-fiber material, producing the highest figures of merit ever recorded for any regenerator tested in that rig over its approximately 20 years of use.

Ibrahim, Mounir↗

Lymphatic involution and early mortality in the young chicken produced by 2.2 GeV protons

Young single-comb white Leghorn cockerels were subjected to single acute doses of either 2.2 GeV protons or 250 kVp X-rays. Since young chickens exposed in the lethal range die within 48 hours of exposure, an hourly tabulation of deaths was recorded for this length of time after exposure. Animals which were exposed to sublethal doses were killed five days after exposure and their major lymphatic organs, (thymus, bursa, and spleen), removed and weighed. In the lethal range, animals exposed to 2.2 GeV protons died sooner than those receiving similar doses of X-rays, but total mortality was similar in each case at similar dose levels. The 48 hour LD sub 50 was determined to be 710 rad. Measured five days after exposure, 50% depression ED sub 50 for lymphatic organs occurred as follows: (1) thymus, 350 rad; (2) pursa, 500 rad, and (3) spleen, 450 rad. In all case R.B.E. values were not different from unity.

Montour, J. L.↗

Lymphoidal involution and delayed homograft rejection in hypoxia-exposed mice.

Investigation of the relationship between histologic and cytochemical response patterns of the thymus, spleen, and lymph nodes of mice exposed to moderate hypoxia (380 mm Hg), and study, by histologic analysis, of the effect of hypoxia exposure on the skin homograft reaction used as an index of immunologic potential. The results obtained include the finding that functional changes in lymphatic organs occur during early weeks of hypoxia acclimation and that these changes probably reduce the ability of an animal to react to an immunological challenge.

Kmetz, J. M.↗

Hydroburst test of a carbon-carbon involute exit cone

A hydroburst test of the aft portion of the PAM-D exit cone and the test procedure are described in detail. The hydrostatic pressure required to buckle the cone was 9.75 psi. Meanwhile, the PAM-D exit cone was modeled using the finite element method and a theoretical bucking pressure (8.76 psi) was predicted using the SPAR finite element code. The modeling technique employed is discussed. By comparing the theoretical to predicted critical pressures, this report verifies the modeling technique and calculates a material knockdown factor for the carbon-carbon exit cone.

Sullivan, Roy M.↗

Cyclic loads tests of carbon involute solid rocket motor outer boot ring segments

The cyclic loads tests performed on the 30-in. segments of the DM-9 (Development Motor-9) configuration solid rocket outer boot ring are described. The tests found that the effect of the cyclic loadings on the structural integrity of the outer boot ring was negligible. The results are compared with a hand analysis of the strength of a 30-in. outer boot ring segment. Several phenomena of engineering interest are also described.

Ahmed, Rafiq↗

Computer aided design of spur gear teeth

Procedures for computer-modeling of spur gear tooth fabrication are given. It is shown that the standard involute tooth form results from a cutter with an involute shape rolling onto a gear blank. Specifically, the envelope of an involute is an involute. Examples are given and applications are discussed.

Huston, R. L.↗

Recirculating Th2 cells induce severe thymic dysfunction via IL-4/STAT6 signaling pathway

Highlights: • Th2 cell is the most powerful factor in the inhibition of T cell development. • The effect caused by Th2 cells is principally due to the direct action of IL-4. • IL-4/STAT6 signaling is a major contributor to the ruins of T cell development. • The effect has a positive significance associated with thymic involution. Thymic involution happened early in life, but a certain ratio of activated CD4{sup +} T cells will persistently recirculate into the thymus from the periphery and it have been suggested to be able to inhibit the development of embryonic thymocytes. Our present study was aimed to elucidate the specific mechanism how activated CD4{sup +} T cells could influence upon developing thymocytes by using fetal thymic organ culture (FTOC) and kidney capsule transplantation. Our results demonstrated that Th2 cells were found to play a fundamental role in the inhibition of embryonic thymocyte development since a very low concentration of Th2 cells could obviously reduce the total number of thymocytes. And this effect was not tenable in other Th cell type. Notably, IL-4, the major cytokine secreted by Th2 cells, was suggested the key factor playing the inhibition role. In addition to reduced cell population, the proportion of double positive (DP) T cells was also heavily decreased. Furthermore, we demonstrated that it was the downstream effector signal transducer and activator of transcription 6 (STAT6) of IL-4 partially manipulate this inhibition. Together, these findings reveal a novel influence of Th2 cells re-entering the thymus on thymic involution.

60 APPLIED LIFE SCIENCES↗

Simulating High Flux Isotope Reactor Core Thermal-Hydraulics via Interdimensional Model Coupling

A coupled interdimensional model is presented for the simulation of the thermal-hydraulic characteristics of the High Flux Isotope Reactor core at Oak Ridge National Laboratory. The model consists of two domains a solid involute fuel plate and the surrounding liquid coolant channel. The fuel plate is modeled explicitly in three-dimensions. The coolant channel is approximated as a twodimensional slice oriented perpendicular to the fuel plate s surface. The two dimensionally-inconsistent domains are linked to one another via interdimensional model coupling mechanisms. The coupled model is presented as a simplified alternative to a fully explicit, fully three-dimensional model. Involute geometries were constructed in SolidWorks. Derivations of the involute construction equations are presented. Geometries were then imported into COMSOL Multiphysics for simulation and modeling. Both models are described in detail so as to highlight their respective attributes in the 3D model, the pursuit of an accurate, reliable, and complete solution; in the coupled model, the intent to simplify the modeling domain as much as possible without affecting significant alterations to the solution. The coupled model was created with the goal of permitting larger portions of the reactor core to be modeled at once without a significant sacrifice to solution integrity. As such, particular care is given to validating incorporated model simplifications. To the greatest extent possible, the decrease in solution time as well as computational cost are quantified versus the effects such gains have on the solution quality. A variant of the coupled model which sufficiently balances these three solution characteristics is presented alongside the more comprehensive 3D model for comparison and validation.

COMSOL HFIR LEU↗

Effects of bearing offset and flexibility on the mesh force distribution of spiral bevel gears

For straight or spiral bevel gears of nominal spherical involute design, the resultant total force vector transmitted by the gear mesh, in the absence of friction, lies in the plane of tooth contact. This force vector can be characterized by three scalar components, two orthogonal force components lying in the plane of contact and the resultant moment taken about the nominal center of the zone of contact. Equations for these three generalized force components are derived. The equations are expressed in terms of tooth pair/gear body stiffnesses, bearing/bearing support flexibility influence coefficients, the shaft input torque, deviations of the tooth running surfaces from perfect spherical involute surfaces, and bearing centerline offsets from the positions occupied by the base cone axes of the perfect involute bevel gear counterparts to the actual gears under consideration. Inertial forces arising from transverse and axial vibrations of the gear bodies are assumed to be negligible in comparison with the bearing support reaction forces.

Mark, W. D.↗

RDS-21 Face-Gear Surface Durability Tests

Experimental fatigue tests were performed to determine the surface durability life of a face gear in mesh with a tapered spur involute pinion. Twenty-four sets of gears were tested at three load levels: 7200, 8185, and 9075 lb-in face gear torque, and 2190 to 3280 rpm face gear speed. The gears were carburized and ground, shot-peened and vibro-honed, and made from VIM-VAR Pyrowear 53 steel per AMS 6308. The tests produced 17 gear tooth spalling failures and 7 suspensions. For all the failed sets, spalling occurred on at least one tooth of all the pinions. In some cases, the spalling initiated a crack in the pinion teeth which progressed to tooth fracture. Also, spalling occurred on some face gear teeth. The AGMA endurance allowable stress for a tapered spur involute pinion in mesh with a face gear was determined to be 275 ksi for the material tested. For the application of a tapered spur involute pinion in mesh with a face gear, proper face gear shim controlled the desired gear tooth contact pattern while proper pinion shim was an effective way of adjusting backlash without severely affecting the contact pattern.

Lewicki, David G.↗

Temporal Nodal Regression and Regional Control After Primary Radiation Therapy for N2-N3 Head-and-Neck Cancer Stratified by HPV Status

Purpose: To compare the temporal lymph node (LN) regression and regional control (RC) after primary chemoradiation therapy/radiation therapy in human papillomavirus-related [HPV(+)] versus human papillomavirus-unrelated [HPV(−)] head-and-neck cancer (HNC). Methods and Materials: All cases of N2-N3 HNC treated with radiation therapy/chemoradiation therapy between 2003 and 2009 were reviewed. Human papillomavirus status was ascertained by p16 staining on all available oropharyngeal cancers. Larynx/hypopharynx cancers were considered HPV(−). Initial radiologic complete nodal response (CR) (≤1.0 cm 8-12 weeks after treatment), ultimate LN resolution, and RC were compared between HPV(+) and HPV(−) HNC. Multivariate analysis identified outcome predictors. Results: A total of 257 HPV(+) and 236 HPV(−) HNCs were identified. The initial LN size was larger (mean, 2.9 cm vs 2.5 cm; P<.01) with a higher proportion of cystic LNs (38% vs 6%, P<.01) in HPV(+) versus HPV(−) HNC. CR was achieved is 125 HPV(+) HNCs (49%) and 129 HPV(−) HNCs (55%) (P=.18). The mean post treatment largest LN was 36% of the original size in the HPV(+) group and 41% in the HPV(−) group (P<.01). The actuarial LN resolution was similar in the HPV(+) and HPV(−) groups at 12 weeks (42% and 43%, respectively), but it was higher in the HPV(+) group than in the HPV(−) group at 36 weeks (90% vs 77%, P<.01). The median follow-up period was 3.6 years. The 3-year RC rate was higher in the HPV(−) CR cases versus non-CR cases (92% vs 63%, P<.01) but was not different in the HPV(+) CR cases versus non-CR cases (98% vs 92%, P=.14). On multivariate analysis, HPV(+) status predicted ultimate LN resolution (odds ratio, 1.4 [95% confidence interval, 1.1-1.7]; P<.01) and RC (hazard ratio, 0.3 [95% confidence interval 0.2-0.6]; P<.01). Conclusions: HPV(+) LNs involute more quickly than HPV(−) LNs but undergo a more prolonged process to eventual CR beyond the time of initial assessment at 8 to 12 weeks after treatment. Post radiation neck dissection is advisable for all non-CR HPV(−)/non-CR N3 HPV(+) cases, but it may be avoided for selected non-CR N2 HPV(+) cases with a significant LN involution if they can undergo continued imaging surveillance. The role of positron emission tomography for response assessment should be investigated.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

The algebra of dual -1 Hahn polynomials and the Clebsch-Gordan problem of sl{sub -1}(2)

The algebra H of the dual -1 Hahn polynomials is derived and shown to arise in the Clebsch-Gordan problem of sl{sub -1}(2). The dual -1 Hahn polynomials are the bispectral polynomials of a discrete argument obtained from the q{yields}-1 limit of the dual q-Hahn polynomials. The Hopf algebra sl{sub -1}(2) has four generators including an involution, it is also a q{yields}-1 limit of the quantum algebra sl{sub q}(2) and furthermore, the dynamical algebra of the parabose oscillator. The algebra H, a two-parameter generalization of u(2) with an involution as additional generator, is first derived from the recurrence relation of the -1 Hahn polynomials. It is then shown that H can be realized in terms of the generators of two added sl{sub -1}(2) algebras, so that the Clebsch-Gordan coefficients of sl{sub -1}(2) are dual -1 Hahn polynomials. An irreducible representation of H involving five-diagonal matrices and connected to the difference equation of the dual -1 Hahn polynomials is constructed.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

Hardened Novikov Gears as the Last Stage of General-Purpose Gear Systems

The creation of general-purpose gear systems with hardened Novikov gears of relatively low precision is considered. By solving three-dimensional elastic-contact problems and modeling, the replacement of expensive high-precision involute gears in the final stage of general-purpose gear systems by less expensive hardened Novikov gears of lower precision is shown to be expedient. Preliminary calculations of prospective high-precision Novikov gears are presented. They offer considerable advantages over their involute counterparts.

42 ENGINEERING↗