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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 55 records · Page 3

Integration of Optical Coherence Tomography Scan Patterns to Augment Clinical Data Suite

Vision changes identified in long duration spaceflight astronauts has led Space Medicine at NASA to adopt a more comprehensive clinical monitoring protocol. Optical Coherence Tomography (OCT) was recently implemented at NASA, including on board the International Space Station in 2013. NASA is collaborating with Heidelberg Engineering to increase the fidelity of the current OCT data set by integrating the traditional circumpapillary OCT image with radial and horizontal block images at the optic nerve head. The retinal nerve fiber layer was segmented by two experienced individuals. Intra-rater (N=4 subjects and 70 images) and inter-rater (N=4 subjects and 221 images) agreement was performed. The results of this analysis and the potential benefits will be presented.

Mason, S.↗

Exploratory Analysis of Carbon Dioxide Levels, Ultrasound and Optical Coherence Tomography Measures of the Eye During ISS Missions

Enhanced screening for the Visual Impairment/Intracranial Pressure (VIIP) syndrome has been implemented to better characterize the ocular and vision changes observed in some long-duration crewmembers. This includes implementation of in-flight ultrasound in 2010 and optical coherence tomography (OCT) in 2013. Potential risk factors for VIIP include cardiovascular health, diet, anatomical and genetic factors, and environmental conditions. Carbon dioxide (CO2), a potent vasodilator, is chronically elevated on the International Space Station (ISS) relative to ambient levels on Earth, and is a plausible risk factor for VIIP. In an effort to understand the possible associations between CO2 and VIIP, this study explores the relationship of ambient CO2 levels on ISS compared to inflight ultrasound and OCT measures of the eye obtained from ISS crewmembers. CO2 measurements were aggregated from Operational Data Reduction Complex and Node 3 major constituent analyzers (MCAs) on ISS or from sensors located in the European Columbus module, as available. CO2 levels in the periods between each ultrasound and OCT session are summarized using timeseries metrics, including time-weighted means and variances. Partial least squares regression analyses are used to quantify the complex relationship between specific ultrasound and OCT measures and the CO2 metrics simulataneously. These analyses will enhance our understanding of the possible associations between CO2 levels and structural changes to the eye which will in turn inform future analysis of inflight VIIP data.

Schaefer, C.↗

Exploratory Analysis of Carbon Dioxide Levels, Ultrasound and Optical Coherence Tomography Measures of the Eye During ISS Missions

Carbon dioxide (CO2) levels on board the International Space Station (ISS) have typically averaged 2.3 to 5.3 mmHg, with large fluctuations occurring over periods of hours and days. CO2 has effects on cerebral vascular tone, resulting in vasodilation and alteration of cerebral blood flow (CBF). Increased CBF leads to elevated intracranial pressure (ICP), a factor leading to visual disturbances, headaches, and other central nervous system symptoms. Ultrasound of the optic nerve and optical coherence tomography (OCT) provide surrogate measurements of ICP; in-flight measurements of both were implemented as enhanced screening tools for the Visual Impairment/Intracranial Pressure (VIIP) syndrome. This analysis examines the relationships between ambient CO2 levels on ISS, ultrasound and OCT measures of the eye in an effort to understand how CO2 may possibly be associated with VIIP and to inform future analysis of in-flight VIIP data.

Schaefer, C.↗

A binary coherent optical receiver for the free-space channel

The structure of a coherent binary optical MAP receiver was derived and the effects of background radiation and phase estimation errors on receiver performance were evaluated. It was found that random phase errors do not affect the performance of the coherent receiver significantly, as long as the standard deviation of the phase error remains less than roughly 0.14 radians (or 8 degrees). It was also shown that background radiation is effectively suppressed by the optical homodyne receiver: Significant deterioration in receiver performance is observed only in the presence of extremely intense background fields. The most notable characteristic of the binary optical homodyne receiver therefore appears to be its ability to achieve quantum limited performance in high background environments, provided that sufficiently accurate estimates of the received phase can be obtained.

Vilnrotter, V. A.↗

Coherent optical pulse reshaping in a resonant molecular absorber

Investigation of the coherent reshaping of short-duration (2 to 40 nsec) N2O laser pulses in a resonant NH3 absorber for a variable number of absorption lengths. It is found that, for small-area square pulses, the reshaping can produce subnanosecond pulses at the leading and trailing edges. A rapid phase reversal gives rise to amplification for times comparable to the transverse relaxation time.

Hamadani, S. M.↗

Low data rate coherent optical link demonstration using frequency stabilized solid state lasers

A low data rate laboratory heterodyne link demonstration operating at 1.06 micron using frequency stabilized Nd:YAG lasers was implemented. The data was modulated onto the optical carrier at 100 kbps using binary pulse position modulation. Phase coherent reception was achieved by closing the receiver phase tracking loop around the piezo-electric and temperature-tuned local oscillator laser. Initial frequency acquisition was accomplished by linearly scanning the LO frequency over the uncertainty range while a combined frequency and phase tracking loop searches for a lock indicator signal. The link performance was experimentally evaluated and compared to the theoretical predictions.

Chen, CHIEN-C.↗

Coherent Optical Receiver for PPM Signals under Atmospheric Turbulence

Adaptive combining of experimentally obtained heterodyned pulse position modulated (PPM) signals with pulse-to-pulse coherence in the presence of simulated spatial distortions resembling atmospheric turbulence is demonstrated. The adaptively combined PPM signals are phased up via an LMS algorithm suitably optimized to operate with PPM in the presence of additive shot-noise. A convergence analysis of the algorithm is presented, and results with both, computer simulated and experimentally obtained PPM signals are analyzed.

coherent detection↗

Noise diffraction patterns eliminated in coherent optical systems

Lens rotation technique of noise diffraction pattern elimination spreads diffracted energy, normally concentrated over small area of image, over much larger annular area. Technique advantages include simplified lens selecting process, reduced clean room requirements, and low cost equipment requirements.

Grebowsky, G. R.↗

Coherent optical data processing and remotely sensed imagery

It is shown that an automatic imaging system consisting of a combination of optical and digital computer elements is feasible and has considerable advantages over direct image scanning systems. With such a system, it is possible to process very large quantities of remotely sensed image spectra.

Macdougall, E. B.↗

Coherent optical instrumentation for measurements of particle parameters

The application of cross-beam Laser Doppler Velocimeter (LDV) for sizing small particles was investigated from September 1973 to August 1974. Theoretical results were obtained by analyzing the scattering characteristics of small particles in a cross-beam LDV system. Theoretical calculations based on scalar diffraction theory and Mie scattering theory were performed. Experimental results were also obtained to compare with theoretical predictions. It is concluded that the forward scattering characteristics of small particles in a cross-beam LDV system can be used for particle sizing.

Chu, W. P.↗