Probing DNA-protein interactions using single-molecule diffusivity contrast
Not Available
Wilson, Hugh↗
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Results for “Protein interactions”
Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.
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Implications of the mutation S164A on Bacillus subtilis levansucrase product specificity and insights into protein interactions acting upon levan synthesis
Abstract not provided
Ortiz-Soto, Maria Elena↗
Structural basis for tunable affinity and specificity of LxCxE-dependent protein interactions with t
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Putta, Sivasankar↗
Predicting protein interactions of the kinase Lck critical to T cell modulation
Not Available
Gao, Mu (ORCID:0000000203783704)↗
Combined Effects of Pressure and Ionic Strength on Protein–Protein Interactions: An Empirical Approach
Not provided.
Biochemistry & Molecular Biology↗
Discovery of MK-4688: an Efficient Inhibitor of the HDM2?p53 Protein?Protein Interaction
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Reutershan, Michael H.↗
Discovery and Optimization of Salicylic Acid-Derived Sulfonamide Inhibitors of the WD Repeat-Containing Protein 5-MYC Protein-Protein Interaction
Abstract not provided
Macdonald, Jonathan D.↗
Structural and Biochemical Characterization of the Flavin-Dependent Siderophore-Interacting Protein
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Valentino, Hannah↗
Phycobilisome’s Exciton Transfer Efficiency Relies on an Energetic Funnel Driven by Chromophore–Linker Protein Interactions
Not Available
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗
Distal protein-protein interactions contribute to nirmatrelvir resistance
Not provided.
Science & Technology - Other Topics↗
Crystal structure of the Rab-binding domain of Rab11 family-interacting protein 2
Abstract not provided
Kearney, Aoife Mairead↗
Uncertainty-Aware Adaptation of Large Language Models for Protein-Protein Interaction Analysis
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97 MATHEMATICS AND COMPUTING↗
Foldy: An open-source web application for interactive protein structure analysis
Foldy is a cloud-based application that allows non-computational biologists to easily utilize advanced AI-based structural biology tools, including AlphaFold and DiffDock. With many deployment options, it can be employed by individuals, labs, universities, and companies in the cloud without requiring hardware resources, but it can also be configured to utilize locally available computers. Foldy enables scientists to predict the structure of proteins and complexes up to 6000 amino acids with AlphaFold, visualize Pfam annotations, and dock ligands with AutoDock Vina and DiffDock. In our manuscript, we detail Foldy’s interface design, deployment strategies, and optimization for various user scenarios. We demonstrate its application through case studies including rational enzyme design and analyzing proteins with domains of unknown function. Furthermore, we compare Foldy’s interface and management capabilities with other open and closed source tools in the field, illustrating its practicality in managing complex data and computation tasks. Our manuscript underlines the benefits of Foldy as a day-to-day tool for life science researchers, and shows how Foldy can make modern tools more accessible and efficient.
59 BASIC BIOLOGICAL SCIENCES↗