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44 records · Page 3

Mars Sample Return: Risk Management & Sample Safety Assessment

Returning samples from Mars has long been a major planetary science objective due to the high scientific value and transformative potential of the resulting data. An exciting dimension of this objective is the potential for the detection of ancient microbiological life, and the possibility of improving our understanding of the evolution of habitable environments on Mars and the development of life on Earth. To ensure that returned samples meet stringent planetary protection requirements and do not expose Earth to potential biohazards, the joint NASA/ESA Sample Receiving Project (SRP) assembled the Sample Safety Assessment Protocol Tiger Team (SSAP-TT). Members were recruited with the specific goal of creating a multi-disciplinary and internationally distributed team of experts in their respective fields across the federal government, academia, and private industry. This team was chartered with reassessing previous sample safety assessment strategies, defining what constitutes a biological hazard, developing a protocol to test for potential biohazards, and establishing a statistical framework to determine if samples are “safe” for release. The team developed a three-step protocol, supported by a Bayesian statistical framework, to assess whether returned samples contain potential biohazards that could present a risk to Earth’s biosphere. Initial conclusions indicated that an effective and comprehensive safety assessment protocol is feasible using modern techniques and does not require an excessive amount of sample consumption or traditional microbiological detection methodology. Herein, we will present an overview of the MSR SRP, the proposed safety assessment protocol, and how aspects of this novel approach can be applied to biological assessment in healthcare product manufacturing practices.

Alvin L Smith↗

Southern Bhutan Ecological Forecasting Tech Paper: Modeling Asian Elephant (Elephas maximus) Habitat Suitability along the Southern Bhutan Border with NASA Earth Observations

Asian elephants (Elephas maximus) are a flagship species essential for the functioning of forest ecosystems, and they also have cultural significance in Bhutan. Elephants receive the highest legal protection as listed under Schedule I of the Bhutan Forests and Nature Conservation Act, 1995. Yet, they face threats of extinction due to poaching for ivory as well as the loss and fragmentation of their habitat. Due to the recent clearing of forests and the growing populations in these areas, there has been an increase in incidents of human-elephant conflict. These conflicts have been detrimental to farmer’s annual harvests and livelihoods and have led to retaliatory killing and injury of elephants in southern Bhutan. The DEVELOP Southern Bhutan Ecological Forecasting team partnered with the Bhutan Foundation and Bhutan Tiger Center to help address this problem. The team integrated NASA Earth observations, including Landsat 5 Thematic Mapper (TM), Landsat 8 Operational Land Imager (OLI), Terra Moderate Resolution Imaging Spectroradiometer (MODIS), and the Shuttle Radar Topography Mission (SRTM) to acquire information on land cover change and elephant habitat suitability along the southern border of Bhutan. The team utilized Esri ArcGIS Pro and Software for Assisted Habitat Modeling (SAHM) for data analysis, modeling, and visualization. The team used elephant occurrence data and environmental variables to model current habitat suitability for migrating elephant populations. This analysis provided partners with maps to inform decisions about the placement and conservation of elephant corridors and helped build their capacity to use satellite data for future studies and project planning.

Palchen Wangchuk↗

Southern Bhutan Ecological Forecasting Project Summary - Modeling Asian Elephant (Elephas Maximus) Habitat Suitability along the Southern Bhutan Border with NASA Earth Observations

Asian elephants (Elephas maximus) are a flagship species essential for the functioning of forest ecosystems, and they also have cultural significance in Bhutan. Elephants receive the highest legal protection as listed under Schedule I of the Bhutan Forests and Nature Conservation Act, 1995. Yet, they face threats of extinction due to poaching for ivory as well as the loss and fragmentation of their habitat. Due to the recent clearing of forests and the growing populations in these areas, there has been an increase in incidents of human-elephant conflict. These conflicts have been detrimental to farmer’s annual harvests and livelihoods and have led to retaliatory killing and injury of elephants in southern Bhutan. The DEVELOP Southern Bhutan Ecological Forecasting team partnered with the Bhutan Foundation and Bhutan Tiger Center to help address this problem. The team integrated NASA Earth observations, including Landsat 5 Thematic Mapper (TM), Landsat 8 Operational Land Imager (OLI), Terra Moderate Resolution Imaging Spectroradiometer (MODIS), and the Shuttle Radar Topography Mission (SRTM) to acquire information on land cover change and elephant habitat suitability along the southern border of Bhutan. The team utilized Esri ArcGIS Pro and Software for Assisted Habitat Modeling (SAHM) for data analysis, modeling, and visualization. The team used elephant occurrence data and environmental variables to model current habitat suitability for migrating elephant populations. This analysis provided partners with maps to inform decisions about the placement and conservation of elephant corridors and helped build their capacity to use satellite data for future studies and project planning.

DEVELOP Project Summary↗

Southern Bhutan Ecological Forecasting III: Utilizing NASA Earth Observations to Model Land Cover Change and Elephant Wildlife Corridors in Southern Bhutan

Habitat loss of the endangered Asian elephants (Elephas maximus) accompanied by rapid urbanization has contributed to the rising human-elephant conflict (HEC) crisis in southern Bhutan. This poses a serious threat to the survival of Asian elephants, a keystone wildlife species essential for maintaining Bhutan’s forest ecosystems and rich biodiversity. With expanding urban areas, HECs present challenges to conservation efforts in the region. The team partnered with the Bhutan Foundation, the Bhutan Tiger Center, and Bhutan Ecological Society to help mitigate this issue using remote sensing technology and NASA Earth observations. The team refined Land Use and Land Cover (LULC) maps for 2010–2019 generated in previous terms and elephant corridor maps to include information on human settlements using Landsat 5 Thematic Mapper (TM) and Landsat 8 Operational Land Imager (OLI) data. We generated LULC change maps and forecasted the LULC to 2030 using TerrSet Land Change Modeler, providing insights into future elephant habitat suitability in southern Bhutan. The results indicated that built-up areas increased approximately 688.9% from 2010 to 2019 and the forecasted 2030 LULC also predicted an increase in built-up areas compared to 2019. Suitable corridors in Gelephu intersect cultivated and built-up areas, indicating close proximity of elephants to humans and a need to research alternative corridor strategies. The end products from this project will aid partner organizations in decision-making processes in urban planning and future conservation strategies that include the refined placement of biological corridors to aid elephant movement and reduce the risk of HECs.

Thinley Yidzin Wangden↗

Southern Bhutan Ecological Forecasting II: Utilizing NASA Earth Observations to Model Land Cover Change and Elephant Wildlife Corridors in Southern Bhutan

The diverse landscapes of Bhutan host a rich biodiversity of animal and plant species. Asian elephants (Elephas maximus) are a flagship keystone wildlife species whose conservation is essential for the functioning of Bhutan’s forest ecosystems. Despite this, increasing habitat loss and human-elephant conflict continue to be detrimental to the survival of Asian elephants. The lack of information on Bhutan’s elephants and land use and land cover (LULC) trends present major challenges for Bhutan in modeling locations with suitable habitat and biological corridors for elephants. The DEVELOP Southern Bhutan Ecological Forecasting II team at NASA Goddard Space Flight Center partnered with the Bhutan Foundation, Bhutan Tiger Center, and Bhutan Ecological Society to help address this problem. The team mapped LULC in Bhutan for 2010 and 2015 by utilizing NASA Earth observations, including Landsat 5 Thematic Mapper (TM) and Landsat 8 Operational Land Imager (OLI) to acquire information on historical LULC patterns and view apparent land cover change. The team used the Linkage Pathways Tool of the Linkage Mapper Toolbox in ArcMap to derive biological corridor maps from habitat suitability model outputs of the previous term and known locations of protected areas in Bhutan. The corridor maps were used to view and assess corridor suitability and connectivity between protected parks. Project results are being provided to partners to help make informed decisions on the placement and conservation of elephant movement corridors.

Thinley Yidzin Wangden↗

Exploiting Kubernetes to Simplify the Deployment and Management of the Multi-purpose CMS Pilot Job Factory

GlideinWMS, a widely utilized workload management system in high-energy physics (HEP) research, serves as the backbone for efficient job provisioning across distributed computing resources. It is utilized by various experiments and organizations, including CMS, OSG, Dune, and FIFE, to create HTCondor pools as large as 600k cores. In particular, a shared factory service historically deployed at UCSD has been configured to interface with more than 500 routes to compute clusters. As part of our team’s initiative to modernize infrastructure and enhance scalability, we undertook the migration of the GlideinWMS factory service into the Kubernetes environment. Leveraging the flexibility and orchestration capabilities of Kubernetes, we successfully deployed the factory service within the OSG Tiger Kubernetes cluster. The major benefits Kubernetes gives us is it streamlines the management and monitoring of the factory infrastructure, and improves fault tolerance through its resilient deployment strategies. Through this case study, we aim to share insights, challenges, and best practices encountered during the migration process. Our experience underscores the benefits of embracing containerization and Kubernetes orchestration for HEP computing infrastructure, paving the way for scalability and resilience in distributed computing environments.

Dost, Jeffrey Michael [UC, San Diego (main)]↗

malbacR: A Package for Standardized Implementation of Batch Correction Methods for Omics Data

Mass spectrometry is a powerful tool for identifying and analyzing small molecules, such as metabolites and lipids, in com-plex biological samples. Liquid chromatography and gas chromatography mass spectrometry studies quite commonly in-volve large numbers of samples, which can require significant time for sample preparation and analyses. To accommodate such studies, the samples are commonly split into batches. Inevitably, variations in sample handling, temperature fluctua-tion, imprecise timing, column degradation and other factors result in systematic errors or biases of the measured abundances between the batches. Numerous methods are available via R packages to assist with batch correction for small molecule om-ics data; however, since these methods were developed by different research teams, the algorithms are available in separate R packages, each with different data input and output formats. We introduce the malbacR package which consolidates eleven common batch effect correction methods for small molecule omics data into one place so users can easily implement and compare: pareto scaling, power scaling, range scaling, ComBat, EigenMS, NOMIS, RUV-random, QC-RLSC, WaveI-CA2.0, TIGER, and SERRF. The malbacR package standardizes data input and output formats across these batch correction methods. The package works in conjunction with the pmartR package, allowing users to seamlessly include batch effect cor-rection in a pmartR workflow without needing any additional data manipulation.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

NOAA-20 ATMS Status: ATMS SDR Team

Data quality looks better than Suomi-NPP (Suomi National Polar-orbiting Partnership): similar biases. Smaller standard deviation of first guess departures and diagnosed observation errors. Weaker striping signal than Suomi-NPP ATMS (Advanced Technology Microwave Sounder). Improved first guess fits to: temperature observations (AMSU-A (Advanced Microwave Sounding Unit-A), CrIS (Cross-track Infrared Sounder), GPSRO (Global Positioning System Radio Occultation)); Humidity observations (MHS (Microwave Humidity Sounder), GEO CSRs (Geostationary Orbit Clear Sky Radiances)). Indicates improved accuracy of short range temperature and humidity forecasts. Neutral to slightly positive forecast scores.

Sensor Data Record (SDR)↗