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Nine different species of organisms were exposed to space flight conditions during the Apollo 16 mission. Each test system was selected because it provided a quantitative method of evaluating some medically important phenomenon. The experiment design and each of the test systems are discussed.
The effect was evaluated of a particular space flight on the survival rate of nine different species. Although a reasonable variety of organisms (viruses, yeasts, filamentous fungi, bacteria, and an invertebrate) were tested under several different conditions, no statistically valid differences could be detected in the survival of flight samples when compared to corresponding ground-based controls. In general, these evaluations were based on multiple observations of from ten to thirty replicates of up to one million cells each. While the results conflict with those of certain other space flight investigations, it is observed that the conditions of a particular space flight cannot be exactly duplicated, and therefore results from different flights are not directly comparable.
The cardiovascular deconditioning observed during and after space flight is characterized in a review of human space and simulation studies and animal simulations. The various simulation techniques (horizontal bed rest, head-down tilt, and water immersion in man, and immobilization of animals) are examined, and sample results are presented in graphs. Countermeasures such as exercise regimens, fluid replacement, drugs, venous pooling, G-suits, oscillating beds, electrostimulation of muscles, lower-body negative pressure, body-surface cooling, and hypoxia are reviewed and found to be generally ineffective or unreliable. The need for future space experimentation in both humans and animals is indicated.
A method of predicting the radiant heat flux distribution produced by a bank of tubular quartz heaters was applied to a radiant system consisting of a single unreflected lamp irradiating a flat metallic incident surface. In this manner, the method was experimentally verified for various radiant system parameter settings and used as a source of input for a finite element thermal analysis. Two finite element thermal analyses were applied to a thermal system consisting of a thin metallic panel exposed to radiant surface heating. A two-dimensional steady-state finite element thermal analysis algorithm, based on Galerkin's Method of Weighted Residuals (GFE), was formulated specifically for this problem and was used in comparison to the thermal analyzers of the Engineering Analysis Language (EAL). Both analyses allow conduction, convection, and radiation boundary conditions. Differences in the respective finite element formulation are discussed in terms of their accuracy and resulting comparison discrepancies. The thermal analyses are shown to perform well for the comparisons presented here with some important precautions about the various boundary condition models. A description of the experiment, corresponding analytical modeling, and resulting comparisons are presented.
A method is developed for predicting the radiant heat flux distribution produced by a bank of quartz radiant heaters which accounts for the specular and diffuse effects of a flat reflector or the diffuse effects of individual parabolic reflectors. This analysis is experimentally verified for a single unreflected lamp and a single lamp with a flat reflector. Observations on the further development of this analysis and experimental validation are discussed.
Application of reference standard reagents to alternatively depolymerize or stabilize microtubules in a cell that undergoes very regular cytoskeleton-dependent shape changes provides a model system in which some expected components of the environments of spacecraft and space can be tested on Earth for their effects on the cytoskeleton. The fertilized eggs of Ilyanassa obsoleta undergo polar lobe formation by repeated, dramatic, constriction and relaxation of a microfilamentous band localized in the cortical cytoplasm and activated by microtubules.
Two materials, titanium diboride and an alumina/titanium diboride composite, exhibit characteristics favorable for use in multiple space applications. These characteristics include low mass (4.52 gm/cc), high strain rate impact resistance, high temperature use (3000oC M.P.), thermal and electrical conductivity, thermal shock resistance, and high visible-range reflectivity. Additionally, the presence of boron in these materials gives them the potential to shield against neutron radiation as well as charged radiation. These materials are flying on MISSE 6 to assess material changes resulting from exposure to the space environment. This study provides a preliminary, ground-based examination of these materials' interactions with individual components of the space environment, in particular atomic oxygen (AO) and neutron radiation, in order to better predict and understand post-flight results. Individual specimens are exposed to ground state AO and surface oxidation is measured. Equivalent exposures of up to 13 months show no rapid oxidation, however evidence indicates some surface oxidation occurring. Other samples are placed near a polyethylene moderated, one Ci Am/Be neutron source to determine their shielding capability. Comparisons between exposed and shielded indium foil, which is activated by transmitted neutrons, measure each material's ability to shield neutrons. Preliminary results indicate a significant shielding benefit provided by both materials.
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Human responses to spacecraft cabin atmosphere, pressure, and contamination, and water supply, diet, and anthropometry
Conversion tables for studies of human responses to aerospace environment
Management of aquatic weeds in complex watersheds and river systems present many challenges to assessment, planning and implementation of management practices for aquatic invasive plants. The Delta Region Areawide Aquatic Weed Project (DRAAWP), a USDA (U. S. Dept. of Agriculture)-sponsored area-wide project, is working to enhance planning, decision-making and operational efficiency of invasive plant management in the California Sacramento-San Joaquin Delta. Satellite and airborne remote sensing are used to map area of plant coverage and estimate biomass density to aid operations and assess management impacts on plant communities. Modeling at local and watershed scales using the SWAT (Soil Water Assessment Tool) modeling tool provides insight into land-use effects on water quality. Environmental variability in the Delta occurs across a range of time scales from long-term climate and seasonal trends to short-term water flow mediated variations. Controlled environment growth studies have been conducted to quantify the growth response of invasive aquatic plants to water quality and other environmental factors. Response time for invasive species response are examined at time scales of weeks, day, and hours using a combination of study duration and growth assessment techniques to assess water quality, temperature (air and water), and light effects. These provide response parameters for plant growth models in response to environmental variation and interact with management and economic models associated with aquatic weed management. Plant growth models are to be informed by remote sensing and applied spatially across the Delta to balance location and type of aquatic plant, growth response to altered environments and phenology. Initial utilization of remote sensing tools developed for mapping of aquatic invasive plants improved operational efficiency in management practices. These assessment methods provide a comprehensive and quantitative view of aquatic invasive plant communities in the California Delta.
Review of literature on effects of space environment on human response to infection
Physiological and behavioral responses to a hyperdynamic environment were examined in four adult male squirrel monkeys. After baseline monitoring at 1 G, monkeys were exposed to one of three conditions: (1) +2 Gz for 60 minutes, (2) +2.9 Gz max for 8 minutes (simulating Space Shuttle launch), or (3) +1.7 Gz max for 19 minutes (simulating Space Shuttle reentry). During all experimental conditions, heart rate rose, and colonic temperature began to decline within the first ten minutes of centrifugation and decreased by as much as 2 C in some instances. Behaviorally, during centrifugation, the monkeys seemed to exhibit drowsiness and fall asleep, an observation not made during the control period. It is concluded that primates are susceptible to acute hyperdynamic field exposure.
The dynamic responses of liquid-fuel droplet vaporization and combustion to ambient pressure oscillations are examined. The analysis is based on the complete sets of conservation equations for both gas and liquid phases, and accommodates detailed treatments of finite-rate chemical kinetics and variable properties. With a full account of thermodynamic phase equilibrium at the droplet surface, the model enables a systematic examination of the effects of ambient flow conditions on the droplet behavior. The responses of hydrocarbon fuel droplets in both sub- and super-critical environments are investigated. Results indicate that the droplet gasification and burning mechanisms depend greatly on the ambient pressure. In particular, a rapid enlargement of the vaporization and combustion responses occurs when the droplet surface reaches its critical point, mainly due to the strong variations of latent heat of vaporization and thermophysical properties at the critical state.
This paper presents comparisons of buffet forcing functions (BFFs) and associated structural responses for the Space Launch System from two data sources: 1) Artemis I (AR01) Developmental Flight Instrumentation (DFI) and 2) transonic wind-tunnel (WT) tests. Failures of DFI sensors prevented the development of a complete set of flight-based BFFs, where each BFF is based on azimuthal integration over 360-degrees of unsteady pressures acquired by sensor rings placed at many longitudinal stations along the vehicle. Instead, a set of equivalent flight- and WT-based BFFs was developed based on functional DFI and WT sensors that share the same locations. Root-mean-square (rms) levels of equivalent BFFs from flight and WT data are in-family for most of the cardinal Mach numbers. However, at stations downstream of the booster forward attachment (FA) protuberance, the rms of flight-based BFFs exceed their WT counterparts. Strikingly, vortex-shedding off the FA protuberance occurs at lower frequencies during flight than in WT experiments. This frequency shift propagates onto the spectrum of flight-measured vs. WT-based structural responses. Aside from vortex-shedding frequency mismatch, a generally good agreement between AR01 and WT-based responses is an indirect indication that WT buffet environments are fairly well representative of their AR01 counterpart.
This paper presents comparisons of buffet forcing functions (BFFs) and associated structural responses for the Space Launch System from two data sources: 1) Artemis I (AR01) Developmental Flight Instrumentation (DFI) and 2) transonic wind-tunnel (WT) tests. Failures of DFI sensors prevented the development of a complete set of flight-based BFFs, where each BFF is based on azimuthal integration over 360-degrees of unsteady pressures acquired by sensor rings placed at many longitudinal stations along the vehicle. Instead, a set of equivalent flight- and WT-based BFFs was developed based on functional DFI and WT sensors that share the same locations. Root-mean-square (rms) levels of equivalent BFFs from flight and WT data are in-family for most of the cardinal Mach numbers. However, at stations downstream of the booster forward attachment (FA) protuberance, the rms of flight-based BFFs exceed their WT counterparts. Strikingly, vortex-shedding off the FA protuberance occurs at lower frequencies during flight than in WT experiments. This frequency shift propagates onto the spectrum of flight-measured vs. WT-based structural responses. Aside from vortex-shedding frequency mismatch, a generally good agreement between AR01 and WT-based responses is an indirect indication that WT buffet environments are fairly well representative of their AR01 counterpart.
Graphite thermochemical response tested in simulated environment for use as thermal shield for hypersonic reentry vehicles
Graphite thermochemical response tested in simulated environment for use as thermal shield for hypersonic reentry vehicles