Measurement of the flow harmonic correlations in pp, p+Pb and low multiplicity Pb+Pb collisions with the ATLAS detector at the LHC
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72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗
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Cells Respond to Distinct Nanoparticle Properties with Multiple Strategies As Revealed by Single-Cell RNA-Seq
The impact of distinct nanoparticle (NP) properties on cellular response and ultimately human health is unclear. This gap is partially due to experimental difficulties in achieving uniform NP loads in the studied cells, creating heterogeneous populations with some cells “overloaded” while other cells are loaded with few or no NPs. Yet gene expression studies have been conducted in the population as a whole, identifying generic responses, while missing unique responses due to signal averaging across many cells, each carrying different loads. Here we applied single-cell RNA-Seq to alveolar epithelial cells carrying defined loads of aminated or carboxylated quantum dots (QDs), showing higher or lower toxicity, respectively. Interestingly, cells carrying lower loads responded with multiple strategies, mostly with upregulated processes, which were nonetheless coherent and unique to each QD type. In contrast, cells carrying higher loads responded more uniformly, with mostly downregulated processes that were shared across QD types. Strategies unique to aminated QDs showed strong upregulation of stress responses, coupled in some cases with regulation of cell cycle, protein synthesis and organelle activities. In contrast, strategies unique to carboxylated QDs showed upregulation of DNA repair and RNA activities, and decreased regulation of cell division, coupled in some cases with upregulation of stress responses and ATP related functions. Together, our studies suggest scenarios where higher NP loads lock cells into uniform responses, mostly shutdown of cellular processes, whereas lower loads allow for unique responses to each NP type that are more diversified, proactive defenses or repairs of the NP insults.
Environmental Molecular Sciences Laboratory↗
Protein cage assembly across multiple length scales
Assembly of protein cages across multiple length scales is described, with an emphasis on their use as functional biomaterials.
Chemistry↗
Hydrodynamic description of an unmagnetized plasma with multiple ion species. II. Two and three ion species plasmas
Paper I [A. N. Simakov and K. Molvig, Phys. Plasmas23, 032115 (2016)] obtained a fluid description for an unmagnetized collisional plasma with multiple ion species. To evaluate collisional plasmatransport fluxes, required for such a description, two linear systems of equations need to be solved to obtain corresponding transport coefficients. In general, this should be done numerically. Herein, the general formalism is used to obtain analytical expressions for such fluxes for several specific cases of interest: a deuterium-tritium plasma; a plasma containing two ion species with strongly disparate masses, which agrees with previously obtained results; and a three ion species plasma made of deuterium, tritium, and gold. We find that these results can be used for understanding the behavior of the aforementioned plasmas, or for verifying a code implementation of the general multi-ion formalism.
70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗
On-chip photonic system using suspended p-n junction InGaN/GaN multiple quantum wells device and multiple waveguides
We propose, fabricate, and characterize the on-chip integration of suspended p-n junction InGaN/GaN multiple quantum wells (MQWs) device and multiple waveguides on the same GaN-on-silicon platform. The integrated devices are fabricated via a wafer-level process and exhibit selectable functionalities for diverse applications. As the suspended p-n junction InGaN/GaN MQWs device operates under a light emitting diode (LED) mode, part of the light emission is confined and guided by the suspended waveguides. The in-plane propagation along the suspended waveguides is measured by a micro-transmittance setup. The on-chip data transmission is demonstrated for the proof-of-concept photonic integration. As the suspended p-n junction InGaN/GaN MQWs device operates under photodiode mode, the light is illuminated on the suspended waveguides with the aid of the micro-transmittance setup and, thus, coupled into the suspended waveguides. The guided light is finally sensed by the photodiode, and the induced photocurrent trace shows a distinct on/off switching performance. These experimental results indicate that the on-chip photonic integration is promising for the development of sophisticated integrated photonic circuits in the visible wavelength region.
71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗
A many-body states picture of electronic friction: The case of multiple orbitals and multiple electronic states
We present a very general form of electronic friction as present when a molecule with multiple orbitals hybridizes with a metal electrode. To develop this picture of friction, we embed the quantum-classical Liouville equation (QCLE) within a classical master equation (CME). Thus, this article extends our previous work analyzing the case of one electronic level, as we may now treat the case of multiple levels and many electronic molecular states. We show that, in the adiabatic limit, where electron transitions are much faster than nuclear motion, the QCLE-CME reduces to a Fokker-Planck equation, such that nuclei feel an average force as well as friction and a random force—as caused by their interaction with the metallic electrons. Finally, we show numerically and analytically that our frictional results agree with other published results calculated using non-equilibrium Green’s functions. Numerical recipes for solving this QCLE-CME will be provided in a subsequent paper.
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗
Cosmological Constraints from Multiple Probes in the Dark Energy Survey
The combination of multiple observational probes has long been advocated as a powerful technique to constrain cosmological parameters, in particular dark energy. The Dark Energy Survey has measured 207 spectroscopically confirmed type Ia supernova light curves, the baryon acoustic oscillation feature, weak gravitational lensing, and galaxy clustering. Here we present combined results from these probes, deriving constraints on the equation of state, w, of dark energy and its energy density in the Universe. Independently of other experiments, such as those that measure the cosmic microwave background, the probes from this single photometric survey rule out a Universe with no dark energy, finding w = -0.80(-0.11)(+0.09). The geometry is shown to be consistent with a spatially flat Universe, and we obtain a constraint on the baryon density of Omega(b) = 0.069(-0.012)(+0.009) that is independent of early Universe measurements. These results demonstrate the potential power of large multiprobe photometric surveys and pave the way for order of magnitude advances in our constraints on properties of dark energy and cosmology over the next decade.
Abbott, T. M. C.↗
Adaptive Urban Traffic Signal Control for Multiple Intersections: An LQR Approach
Traffic congestion leads to severe problems especially in urban traffic networks. It increases the chance of accidents, energy waste, and social costs. In order to address these problems, an adaptive linear quadratic regulator (LQR) approach is developed for traffic signal control at multiple intersections in an urban area. The proposed method controls the green time of the traffic signals to reduce traffic congestion and smooth traffic flow. Real-world data from vision-based traffic sensors are used to build the traffic network model, which mimics the real-world traffic behavior. In addition, the proposed control utilizes recursive least square parameter estimation, which is capable of tracking dynamic changes in traffic conditions. Simulation of Urban MObility (SUMO) is used to analyze the efficacy of the proposed method. Results of the simulation show that the proposed method outperforms pretimed control in various aspects.
adaptive LQR control↗
Multiple interaction points in ghost collisions
The Ghost Collider makes use of unique “ghost” bunches, which are electrically neutral combinations of electrons and positrons within the same RF bucket, eliminates the beam-beam effects typically present at the interaction point (IP) in conventional colliders. This allows for the novel possibility of placing multiple interaction regions in series, achieving additive luminosity without introducing significant disruption. However, to get higher luminosity, the beta functions at the IP reaches millimeter scale, which in turn adds significant chromatic contribution to the collider. Correcting these chromatic effects is essential to maintain beam stability and ensure high luminosity during collider operation. By carefully adjusting the phase advance between two IRs that are placed in series, it becomes possible to cancel chromaticity globally, enabling stable collider operation while preserving high luminosity. In this paper we discuss the design of such IR/IRs to be used in a ghost collider.
Accelerator Physics↗
On-line self-organizing control of multiple- goal, multiple-actuator systems.
Synthesis and design of on-line self-organizing control of multiple goal, multiple actuator systems
ON-LINE PROGRAMMING↗
Input-output properties of multiple-input multiple-output discrete systems, part 2
Stability criteria for multiple input, multiple output discrete systems
Desoer, C. A.↗
A comparative study of Conroy and Monte Carlo methods applied to multiple quadratures and multiple scattering
An efficient numerical method of multiple quadratures, the Conroy method, is applied to the problem of computing multiple scattering contributions in the radiative transfer through realistic planetary atmospheres. A brief error analysis of the method is given and comparisons are drawn with the more familiar Monte Carlo method. Both methods are stochastic problem-solving models of a physical or mathematical process and utilize the sampling scheme for points distributed over a definite region. In the Monte Carlo scheme the sample points are distributed randomly over the integration region. In the Conroy method, the sample points are distributed systematically, such that the point distribution forms a unique, closed, symmetrical pattern which effectively fills the region of the multidimensional integration. The methods are illustrated by two simple examples: one, of multidimensional integration involving two independent variables, and the other, of computing the second order scattering contribution to the sky radiance.
Deepak, A.↗
A comparison of Frequency Domain Multiple Access (FDMA) and Time Domain Multiple Access (TDMA) approaches to satellite service for low data rate Earth stations
A technological and economic assessment is made of providing low data rate service to small earth stations by satellite at Ka-band. Various Frequency Domain Multiple Access (FDMA) and Time Domain Multiple Access (TDMA) scenarios are examined and compared on the basis of cost to the end user. Very small stations (1 to 2 meters in diameter) are found not to be viable alternatives to available terrestrial services. However, medium size (3 to 5 meters) earth stations appear to be very competitive if a minimum throughput of about 1.5 Mbs is maintained. This constrains the use of such terminals to large users and shared use by smaller users. No advantage was found to the use of FDMA. TDMA had a slight advantage from a total system viewpoint and a very significant advantage in the space segment (about 1/3 the required payload weight for an equivalent capacity).
Stevens, G.↗
Convergence characteristics of the multiple input, multiple output LMS algorithm
The convergence characteristics of the multiple input, multiple output LMS algorithm, as applied to active noise and vibration control systems, are examined. The mean square error during the convergence process, as well as the final converged value, are examined analytically and in computer simulation. It is shown that the ratio of number of error sensors to number of control sources has a significant influence upon both the converging and converged value of the mean square error. Other active control system variables, such as the inherent time delays and structural/acoustic transfer functions, are also shown to have a significant influence upon the convergence process.
Snyder, Scott D.↗
Implementation and Characterization of Three-Dimensional Particle-in-Cell Codes on Multiple-Instruction-Multiple-Data Massively Parallel Supercomputers
A three-dimensional electrostatic particle-in-cell (PIC) plasma simulation code has been developed on coarse-grain distributed-memory massively parallel computers with message passing communications. Our implementation is the generalization to three-dimensions of the general concurrent particle-in-cell (GCPIC) algorithm. In the GCPIC algorithm, the particle computation is divided among the processors using a domain decomposition of the simulation domain. In a three-dimensional simulation, the domain can be partitioned into one-, two-, or three-dimensional subdomains ("slabs," "rods," or "cubes") and we investigate the efficiency of the parallel implementation of the push for all three choices. The present implementation runs on the Intel Touchstone Delta machine at Caltech; a multiple-instruction-multiple-data (MIMD) parallel computer with 512 nodes. We find that the parallel efficiency of the push is very high, with the ratio of communication to computation time in the range 0.3%-10.0%. The highest efficiency (> 99%) occurs for a large, scaled problem with 64(sup 3) particles per processing node (approximately 134 million particles of 512 nodes) which has a push time of about 250 ns per particle per time step. We have also developed expressions for the timing of the code which are a function of both code parameters (number of grid points, particles, etc.) and machine-dependent parameters (effective FLOP rate, and the effective interprocessor bandwidths for the communication of particles and grid points). These expressions can be used to estimate the performance of scaled problems--including those with inhomogeneous plasmas--to other parallel machines once the machine-dependent parameters are known.
Lyster, P. M.↗
Heat Load Sharing in a Capillary Pumped Loop with Multiple Evaporators and Multiple Condensers
This paper describes the heat load sharing function among multiple parallel evaporators in a capillary pumped loop (CPL). In the normal mode of operation, the evaporators cool the instruments by absorbing the waste heat. When an instruments is turned off, the attached evaporator can keep it warm by receiving heat from other evaporators serving the operating instruments. This is referred to as heat load sharing. A theoretical basis of heat load sharing is given first. The fact that the wicks in the powered evaporators will develop capillary pressure to force the generated vapor to flow to cold locations where the pressure is lower leads to the conclusion that heat load sharing is an inherent function of a CPL with multiple evaporators. Heat load sharing has been verified with many CPLs in ground tests. Experimental results of the Capillary Pumped Loop 3 (CAPL 3) Flight Experiment are presented in this paper. Factors that affect the amount of heat being shared are discussed. Some constraints of heat load sharing are also addressed.
Ku, Jentung↗
Heat Load Sharing in a Loop Heat Pipe with Multiple Evaporators and Multiple Condensers
This paper describes the heat load sharing function among multiple parallel evaporators in a loop heat pipe (LHP). Each evaporator can be attached to an instrument. In the normal mode of operation, each evaporator will cool the corresponding instrument by absorbing the waste heat. When an instrument is turned off, the attached evaporator can keep it warm by receiving heat from other evaporators serving the operating instruments. This is referred to as heat load sharing. The fact that the wicks in the powered evaporators will develop capillary pressure to force the vapor that is being generated to flow to cold locations where the pressure is lower leads to the conclusion that heat load sharing is an inherent function of an LHP with multiple evaporators. This paper presents a theoretical basis of the LHP heat load sharing operation, and experimental results from ground tests of an LHP with two evaporator and two condensers. Factors that affect the amount of heat being shared are also discussed.
Ku, Jentung↗