Search NASA⌕ Search

SEARCH · Search NASA

Results for “preventative”

Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 55 records · Page 3
All sourcesNASA NTRSDOE OSTI
NASA NTRS1993

Design of a Vehicle-Based Intervention System to Prevent Ozone Loss

Reduced quantities of ozone in the atmosphere allow greater levels of ultraviolet (UV) radiation to reach the earth's surface. The 1992/1993 project goals for the Virginia Tech Senior Design Team were to 1) understand the processes which contribute to stratospheric ozone loss, 2) examine ways to prevent ozone loss, and 3) define the requirements for an implementation vehicle to carry out the prevention scheme. A scheme proposed by R.J. Cicerone, el al late in 1991 was selected because of its supporting research and economic feasibility. This scheme uses hydrocarbon injected into the Antarctic ozone hole to form stable compounds with free chlorine, thus reducing ozone depletion. A study of the hydrocarbon injection requirements determined that 130 aircraft traveling Mach 2.4 at a maximum altitude of 66,000 ft. would provide the most economic approach to preventing ozone loss. Each aircraft would require an 8,000 nm. range and be able to carry 35,000 lbs. of propane. The propane would be stored in a three-tank high pressure system. Modularity and multi-role functionality were selected to be key design features. Missions originate from airports located in South America and Australia.

Mason, William H.↗
NASA NTRS2003

Plasma membrane disruption: repair, prevention, adaptation

Many metazoan cells inhabit mechanically stressful environments and, consequently, their plasma membranes are frequently disrupted. Survival requires that the cell rapidly repair or reseal the disruption. Rapid resealing is an active and complex structural modification that employs endomembrane as its primary building block, and cytoskeletal and membrane fusion proteins as its catalysts. Endomembrane is delivered to the damaged plasma membrane through exocytosis, a ubiquitous Ca2+-triggered response to disruption. Tissue and cell level architecture prevent disruptions from occurring, either by shielding cells from damaging levels of force, or, when this is not possible, by promoting safe force transmission through the plasma membrane via protein-based cables and linkages. Prevention of disruption also can be a dynamic cell or tissue level adaptation triggered when a damaging level of mechanical stress is imposed. Disease results from failure of either the preventive or resealing mechanisms.

NASA Discipline Cell Biology↗
NASA NTRS1989

Blockade of 5-hydroxytryptamine3 receptors prevents cisplatin-induced but not motion- or xylazine-induced emesis in the cat

5-Hydroxytryptamine3 antagonists have been reported to prevent emesis elicited by cisplatin and radiation. This study investigated the possibility that drugs with this mechanism of action may be useful in preventing emesis elicited by other stimuli. The drugs ICS 205-930 (0.1 and 1.0 mg/kg) and MDL 72222 (0.1 and 1.0 mg/kg) were administered SC to cats before challenging them with either provocative motion or an emetic dose of xylazine. In no instance was a significant reduction in emesis evident. Zacopride was also administered before motion testing (0.01 to 10.0 mg/kg) and found to not have efficacy. To test the possibility that species or route of administration were factors in the negative results, 1.0 mg/kg of ICS 205-930 was administered SC before IV infusion of 7.5 mg/kg of cisplatin. There was a total suppression of emesis for the duration of the six-hour observation periods. This result verifies other work which found 5-hydroxytryptamine3 antagonists to be effective in preventing emesis elicited by cancer chemotherapeutic treatments. However, there is no evidence that they are effective in other syndromes, such as motion sickness and xylazine-induced emesis.

NASA Discipline Number 16-10↗
NASA NTRS2007

Cockpit Technology for Prevention of General Aviation Runway Incursions

General aviation accounted for 74 percent of runway incursions but only 57 percent of the operations during the four-year period from fiscal year (FY) 2001 through FY2004. Elements of the NASA Runway Incursion Prevention System were adapted and tested for general aviation aircraft. Sixteen General Aviation pilots, of varying levels of certification and amount of experience, participated in a piloted simulation study to evaluate the system for prevention of general aviation runway incursions compared to existing moving map displays. Pilots flew numerous complex, high workload approaches under varying weather and visibility conditions. A rare-event runway incursion scenario was presented, unbeknownst to the pilots, which represented a typical runway incursion situation. The results validated the efficacy and safety need for a runway incursion prevention system for general aviation aircraft.

Prinzel, Lawrence J., III↗
NASA NTRS1939

An Investigation of the Prevention of Ice on the Airplane Windshield

An investigation has been completed on several methods for the prevention and removal of ice on an airplane windshield. Tests were made on the use of electric heating, hot-air heating, and an alcohol-dispensing, rotating wiper blade. The results showed that vision through the airplane windshield could be maintained during severe icing conditions by the use of heat. When put in operation prior to the formation of ice on the windshield, the rotating wiper blade prevented the formation of ice. A combination system that employs the use of heated air and a rotating wiper blade would appear to give protection against the formation of ice on the windshield exterior, prevent frost on the interior, and provide for the removal of rainfall.

Rodert, Lewis A.↗
NASA NTRS1939

Investigation of an Electrically Heated Airplane Windshield for Ice Prevention, Special Report

A study was made at the National Advisory Committee for Aeronautics Laboratory of the operation of an electrically heated glass panel, which simulated a segment of an airplane windshield, to determine if ice formations, which usually result in the loss of visibility, could be prevented. Tests were made in the 7- by 3-foot ice tunnel, and in flight, under artificially created ice-forming conditions. Ice was prevented from forming on the windshield model in the tunnel by 1.25 watts of power per square inch with the air temperature at 23 F and a velocity of 80 miles per hour. Using an improved model in flight, ice was prevented by 1.43 watts of power per square inch of protected area and 2 watts per inch concentrated in the rim, with the air temperature at 26 F and a velocity of 120 miles per hour. The removal of a preformed ice cap was effected to a limited extent in the tunnel by the use of 1.89 watts of power per square inch when the temperature and velocity were 25 F and 80 miles per hour, respectively. The results indicate that service tests with an improved design are justified.

Rodert, Lewis A.↗
NASA NTRS2010

FOD Prevention at NASA-Marshall Space Flight Center

NASA-MSFC directive MID 5340.1 requires FOD prevention for all flight hardware projects, and requires all support organizations to comply. MSFC-STD-3598 implements a standard approach for FOD prevention, tailored from NAS 412. Three levels of FOD Sensitive Area are identified, adopting existing practices at other NASA facilities. Additional emphasis is given to prevention of impact damage and mitigation of facility FOD sources, especially leaks and spills. Impact Damage Susceptible (IDS) items are identified as FOD-sensitive as well as hardware vulnerable to entrapment of small items.

Lowrey, Nikki M.↗
NASA NTRS2011

FOD Prevention at NASA-Marshall Space Flight Center

NASA now requires all flight hardware projects to develop and implement a Foreign Object Damage (FOD) Prevention Program. With the increasing use of composite and bonded structures, NASA now also requires an Impact Damage Protection Plan for these items. In 2009, Marshall Space Flight Center released an interim directive that required all Center organizations to comply with FOD protocols established by on-site Projects, to include prevention of impact damage. The MSFC Technical Standards Control Board authorized the development of a new MSFC technical standard for FOD Prevention.

Lowrey, Nikki M.↗
NASA NTRS2012

Validation of Safety-Critical Systems for Aircraft Loss-of-Control Prevention and Recovery

Validation of technologies developed for loss of control (LOC) prevention and recovery poses significant challenges. Aircraft LOC can result from a wide spectrum of hazards, often occurring in combination, which cannot be fully replicated during evaluation. Technologies developed for LOC prevention and recovery must therefore be effective under a wide variety of hazardous and uncertain conditions, and the validation framework must provide some measure of assurance that the new vehicle safety technologies do no harm (i.e., that they themselves do not introduce new safety risks). This paper summarizes a proposed validation framework for safety-critical systems, provides an overview of validation methods and tools developed by NASA to date within the Vehicle Systems Safety Project, and develops a preliminary set of test scenarios for the validation of technologies for LOC prevention and recovery

Belcastro, Christine M.↗
NASA NTRS2012

Loss of Control Prevention and Recovery: Onboard Guidance, Control, and Systems Technologies

Loss of control (LOC) is one of the largest contributors to fatal aircraft accidents worldwide. LOC accidents are complex in that they can result from numerous causal and contributing factors acting alone or (more often) in combination. These LOC hazards include vehicle impairment conditions, external disturbances; vehicle upset conditions, and inappropriate crew actions or responses. Hence, there is no single intervention strategy to prevent these accidents. NASA previously defined a comprehensive research and technology development approach for reducing LOC accidents and an associated integrated system concept. Onboard technologies for improved situation awareness, guidance, and control for LOC prevention and recovery are needed as part of this approach. Such systems should include: LOC hazards effects detection and mitigation; upset detection, prevention and recovery; and mitigation of combined hazards. NASA is conducting research in each of these areas. This paper provides an overview of this research, including the near-term LOC focus and associated analysis, as well as preliminary flight system architecture.

Belcastro, Christine M.↗
NASA NTRS2014

High Intensity Exercise Countermeasures does not Prevent Orthostatic Intolerance Following Prolonged Bed Rest

Approximately 20% of Space Shuttle astronauts became presyncopal during operational stand and 80deg head‐up tilt tests, and the prevalence of orthostatic intolerance increases after longer missions. Greater than 60% of the US astronauts participating in Mir and early International Space Station missions experienced presyncope during post‐flight tilt tests, perhaps related to limitations of the exercise hardware that prevented high intensity exercise training until later ISS missions. The objective of this study was to determine whether an intense resistive and aerobic exercise countermeasure program designed to prevent cardiovascular and musculoskeletal deconditioning during 70 d of bed rest (BR), a space flight analog, would protect against post‐BR orthostatic intolerance. METHODS Twenty‐six subjects were randomly assigned to one of three groups: non‐exercise controls (n=11) or one of two exercise groups (ExA, n=8; ExB, n=7). Both ExA and ExB groups performed the same resistive and aerobic exercise countermeasures during BR, but one exercise group received testosterone supplementation while the other received a placebo during BR in a double‐blinded fashion. On 3 d/wk, subjects performed lower body resistive exercise and 30 min of continuous aerobic exercise (≥75% max heart rate). On the other 3 d/wk, subjects performed only highintensity, interval‐style aerobic exercise. Orthostatic intolerance was assessed using a 15‐min 80 head‐up tilt test performed 2 d (BR‐2) before and on the last day of BR (BR70). Plasma volume was measured using carbon monoxide rebreathing on BR‐3 and before rising on the first recovery day (BR+0). The code for the exercise groups has not been broken, and results are reported here without group identification. RESULTS Only one subject became presyncopal during tilt testing on BR‐2, but 7 of 11 (63%) controls, 3 of 8 (38%) ExA, and 4 of 7 (57%) ExB subjects were presyncopal on BR70. Survival analysis of post‐BR tilt tests revealed no differences (p=0.77) between groups. Plasma volume (absolute or relative to body mass index) decreased (p<0.001) from pre to post‐BR, with no differences between groups. CONCLUSIONS These preliminary results corroborate previous reports that the performance of a vigorous exercise countermeasure protocol during BR, even with testosterone supplementation, does not protect against orthostatic intolerance or plasma volume loss. Preventing post‐BR orthostatic intolerance may require additional countermeasures, such as orthostatic stress during BR or end‐of‐BR fluid infusion.

Platts, Steven H.↗
NASA NTRS2015

High Intensity Resistive and Rowing Exercise Countermeasures Do Not Prevent Orthostatic Intolerance Following 70 Days of Bed Rest

More than 60% of US astronauts participating in Mir and early International Space Station missions (greater than 5 months) were unable to complete a 10‐min 80 deg head‐up tilt test on landing day. This high incidence of post‐spaceflight orthostatic intolerance may be related to limitations of the inflight exercise hardware that prevented high intensity training. PURPOSE: This study sought to determine if a countermeasure program that included intense lower‐body resistive and rowing exercises designed to prevent cardiovascular and musculoskeletal deconditioning during 70 days of 6 deg head-down tilt bed rest (BR), a spaceflight analog, also would protect against post‐ BR orthostatic intolerance. METHODS: Sixteen males participated in this study and performed no exercise (Control, n=10) or performed an intense supine exercise protocol with resistive and aerobic components (Exercise, n=6). On 3 days/week, exercise subjects performed lower body resistive exercise and a 30‐min continuous bout of rowing (greater than or equal to 75% max heart rate). On 3 other days/week, subjects performed only high‐intensity, interval‐style rowing. Orthostatic intolerance was assessed using a 15‐min 80 deg head‐up tilt test performed 2 days (BR‐2) before and on the last day of BR (BR70). Plasma volume was measured using a carbon monoxide rebreathing technique on BR‐3 and before rising on the first recovery day (BR+0). RESULTS: Following 70 days of BR, tilt tolerance time decreased significantly in both the Control (BR‐2: 15.0 +/- 0.0, BR70: 9.9 +/- 4.6 min, mean +/- SD) and Exercise (BR‐2: 12.2 +/- 4.7, BR70: 4.9 +/- 1.9 min) subjects, but the decreased tilt tolerance time was not different between groups (Control: ‐34 +/- 31, Exercise: ‐56 +/- 16%). Plasma volume also decreased (Control: ‐0.56 +/- 0.40, Exercise: ‐0.48 +/- 0.33 L) from pre to post‐BR, with no differences between groups (Control: ‐18 +/- 11%, Exerciser: ‐15 +/-1 0%). CONCLUSIONS: These findings confirm previous reports in shorter BR studies that the performance of an exercise countermeasure protocol by itself during BR does not prevent orthostatic intolerance or plasma volume loss. This suggests that protection against orthostatic intolerance in astronauts following long‐duration spaceflight will require an additional intervention, such as periodic orthostatic stress, fluid repletion, and/or lower‐body compression garments.

Lee, Stuart M. C.↗
NASA NTRSDate not supplied

Overview of NASA's Advanced Air Transport Technology and Revolutionary Vertical Lift Technology Projects, with a Focus on Failure Prevention Research

An overview of NASA Aeronautics is presented with an emphasis on where machinery failure prevention is important to the enterprise. NASA has failure prevention research in areas where new technologies have entered the landscape such as the electrification of propulsion systems. Failure prevention and safety monitoring of machinery is also a routine part of the specialized testing that NASA does.

Reliability, advanced air mobility, subsonic trans↗
NASA NTRS1929

Fire prevention on airplanes. Part I

Various methods for preventing fires in airplanes are presented with most efforts centering around prevention of backfires, new engine and carburetor designs, as well as investigations on different types of fuels.

EXHAUST GASES - FIRE PREVENTION↗
NASA NTRSDate not supplied

A physician’s working group guides COVID-19 prevention in a mission critical environment

Background A team was assembled at the National Aeronautics and Space Administration’s (NASA) Johnson Space Center (JSC) to help navigate the shifting COVID-19 pandemic. Their goal was to mitigate the impact of COVID on astronauts, other essential personnel, and the human spaceflight program. This team supplemented the JSC Pandemic Incident Response Group, whose function is to set policy for the overall management of JSC’s COVID-19 mitigations for all onsite mission-essential and mission-critical activities, including health policy. Context The first mission to return to Earth from the International Space Station at the start of the pandemic returned when there was limited information about the transmission and prevention of COVID-19. The medical leadership at JSC determined that a dedicated team was required to navigate the uncharted waters of the pandemic. Description of Activities Issues tackled by this panel included: prevention of COVID-19 transmission during altitude, dive, and spacecraft training – activities that require prolonged close contact between multiple individuals who often cannot safely wear face masks; mitigating the risks of domestic and international travel for essential personnel; securing COVID-19 testing from local and foreign hospital systems; acquiring antigen and PCR analyzers for in-house testing; and the development of quarantine policies for crewed spacecraft launches and landings in Kazakhstan and the United States. The panel also provides clinical return-to-work guidance for cases of COVID-19 in essential personnel.

covid↗
NASA NTRS1972

Investigation of an automatic spin prevention system for fighter airplanes

An investigation was conducted to evaluate the effectiveness of an automatic spin-prevention system for current fighter airplanes as a first step in determining the feasibility of such a system. The concept makes use of the components of the conventional flight-control system with the addition of control logic to monitor angle of attack, yaw rate, and normal acceleration. Analytical techniques were used to study the system concept applied to three representative fighter configurations, and model flight tests were employed to evaluate a prototype system on a representative fighter configuration. Emphasis was placed on the development of the control logic required. A discussion of possible implementations of the system concept is presented. Results of the investigation indicated that a relatively simple system (with full control authority) was effective in preventing the developed spins of the fighter configurations considered and that the system design is dependent on the stall and spin characteristics of the particular airplane.

Gilbert, W. P.↗