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At least 55 records · Page 3

Isotropic seismic radiation from rock damage and dilatancy

SUMMARY We present semi-analytical and numerical results on isotropic radiation expected to be generated by seismic sources with damaged dilatant materials that sustain during failure an overall shear deformation. The results are derived for inclusions with different stiffness components, including those responsible for shear-volumetric coupling in dilatant material, and different geometries, in a surrounding elastic solid. The obtained relations indicate that the isotropic seismic potency and seismic moment components are proportional to the shear potency components multiplied by the aspect ratio between the thickness and length of the source zone. For a typical rupture zone with a thin tabular geometry, the expected small aspect ratio explains the general seismological observations of small isotropic radiation. However, isotropic radiation induced by dynamic dilation for short and thick sources is more pronounced and may reach for spherical sources sustaining shear deformation 18 per cent of the shear components. Sources that include also tensile components and explosions can produce larger isotropic radiation. The results provide rigorous relations that can be used to estimate different source properties in numerical simulations, experiments and field studies.

Geochemistry & Geophysics↗

Radiation Testing for High-Resolution Radiation-Hardened Camera System (Final CRADA Report)

The nuclear energy industry needs higher-image quality and higher rad-hard vision systems for refueling and inspection operations that are required every 12-18 months for all operating commercial reactors. During refueling operations, the serial numbers of fuel assemblies need to be visually verified in a challenging high radiation environment with dose rates on the order of 1kGy/hr. at the top of the core (approximately 10 days after shutdown). Vega Wave Systems has developed and built a radiation hard vision system that: 1. has high radiation hardness, 2. demonstrated best in the industry image quality, 3. has small size and weight, and 4. does not suffer from radiation-induced noise. ANL-1060 (02/13/2023) The proprietary Enduray vision system from Vega Wave Systems, Inc. is designed to withstand more than 400x the radiation level of the Vidicon-based systems, currently the highest radiation tolerant system in use today. The Van De Graaff (VDG) electron accelerator at Argonne National Laboratory is ideally suited for testing of Enduray vision system. VDG provides a broad band (up to 3 MeV) x-ray source that reasonably approximates the energy and spectrum of the gamma radiation expected at the top of a nuclear core 10 days after shutdown (~1kGy/hr.), is easily controlled for variable tests, and will not activate the parts under radiation for ease of timely and close inspection and characterization of the system in case of operational issues.

11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗

Cirrus Cloud Radiative and Microphysical Properties from Ground Observations and In Situ Measurements During FIRE 1991 and Their Application to Exhibit Problems in Cirrus Solar Radiative Transfer Modeling

Measurements from the FIRE 1991 cirrus cloud field experiment in the central United States are presented and analyzed. The first part focuses on cirrus microphysical properties. Aircraft 2D-probe in situ data at different cloud altitudes were evaluated for cirrus cases on four different days. Also presented are simultaneous data samples from balloonborne videosondes. Only these balloonsondes could detect the smaller crystals. Their data suggest (at least for midlatitude altitudes below 10 km) that ice crystals smaller than 15 microns in size are rare and that small ice crystals not detected by 2D-probe measurements are radiatively of minor importance, as overlooked 2D-probe crystals account for about 10% of the total extinction. The second part focuses on the link between cirrus cloud properties and radiation. With cloud macrophysical properties from surface remote sensing added to the microphysical data and additional radiation measurements at the surface, testbeds for radiative transfer models were created. To focus on scattering processes, model evaluations were limited to the solar radiative transfer by comparing calculated and measured transmissions of sunlight at the surface. Comparisons under cloud-free conditions already reveal a model bias of about +45 W/sq m for the hemispheric solar downward broadband flux. This discrepancy, which is (at least in part) difficult to explain, has to be accounted for in comparisons involving clouds. Comparisons under cirrus cloud conditions identify as the major obstacle in cirrus solar radiative transfer modeling the inability of one-dimensional radiative transfer models to account for horizontal inhomogeneities. The successful incorporation of multidimensional radiative transfer effects will depend not only on better models but critically on the ability to measure and to define characteristic inhomogeneity scales of cloud fields. The relative minor error related to the microphysical treatment is in part a reflection of the improved understanding on solar scattering on ice crystals over the last decade and of the available wealth on ice-crystal size and shape data for this study. In absence of this information, uncertainties from microphysical cirrus model assumptions will remain high.

Kinne, Stefan↗

Radiation-Induced Leukemia at Doses Relevant to Radiation Therapy: Modeling Mechanisms and Estimating Risks

Because many cancer patients are diagnosed earlier and live longer than in the past, second cancers induced by radiation therapy have become a clinically significant issue. An earlier biologically based model that was designed to estimate risks of high-dose radiation induced solid cancers included initiation of stem cells to a premalignant state, inactivation of stem cells at high radiation doses, and proliferation of stem cells during cellular repopulation after inactivation. This earlier model predicted the risks of solid tumors induced by radiation therapy but overestimated the corresponding leukemia risks. Methods: To extend the model to radiation-induced leukemias, we analyzed in addition to cellular initiation, inactivation, and proliferation a repopulation mechanism specific to the hematopoietic system: long-range migration through the blood stream of hematopoietic stem cells (HSCs) from distant locations. Parameters for the model were derived from HSC biologic data in the literature and from leukemia risks among atomic bomb survivors v^ ho were subjected to much lower radiation doses. Results: Proliferating HSCs that migrate from sites distant from the high-dose region include few preleukemic HSCs, thus decreasing the high-dose leukemia risk. The extended model for leukemia provides risk estimates that are consistent with epidemiologic data for leukemia risk associated with radiation therapy over a wide dose range. For example, when applied to an earlier case-control study of 110000 women undergoing radiotherapy for uterine cancer, the model predicted an excess relative risk (ERR) of 1.9 for leukemia among women who received a large inhomogeneous fractionated external beam dose to the bone marrow (mean = 14.9 Gy), consistent with the measured ERR (2.0, 95% confidence interval [CI] = 0.2 to 6.4; from 3.6 cases expected and 11 cases observed). As a corresponding example for brachytherapy, the predicted ERR of 0.80 among women who received an inhomogeneous low-dose-rate dose to the bone marrow (mean = 2.5 Gy) was consistent with the measured ERR (0.62, 95% Cl =-0.2 to 1.9). Conclusions: An extended, biologically based model for leukemia that includes HSC initiation, inactivation, proliferation, and, uniquely for leukemia, long-range HSC migration predicts, %Kith reasonable accuracy, risks for radiationinduced leukemia associated with exposure to therapeutic doses of radiation.

Shuryak, Igor↗

Radiation Transport Modeling and Assessment to Better Predict Radiation Exposure, Dose, and Toxicological Effects to Human Organs on Long Duration Space Flights

NASA's long-range plans include possible human exploratory missions to the moon and Mars within the next quarter century. Such missions beyond low Earth orbit will expose crews to transient radiation from solar particle events which include high-energy galactic cosmic rays and high-energy protons. Because the radiation levels in space are high and the missions long, adequate shielding is needed to minimize the deleterious health effects of exposure to radiation. The focus of this study is radiation exposure to the blood-forming organs of the NASA astronauts. NASA/JSC developed the Phantom Torso Experiment for Organ Dose Measurements which housed active and passive dosimeters that would monitor and record absorbed radiation levels at vital organ locations. This experiment was conducted during the STS-9 I mission in May '98 and provided the necessary space radiation data for correlation to results obtained from the current analytical models used to predict exposure to the blood-forming organs. Numerous models (i.e., BRYNTRN and HZETRN) have been developed and used to predict radiation exposure. However, new models are continually being developed and evaluated. The Space Environment Information Systems (SPENVIS) modeling program, developed by the Belgian Institute for Space Aeronomy, is to be used and evaluated as a part of the research activity. It is the intent of this research effort to compare the modeled data to the findings from the STS-9 I mission; assess the accuracy and efficiency of this model; and to determine its usefulness for predicting radiation exposure and developing better guidelines for shielding requirements for long duration manned missions.

Denkins, Pamela↗

Evaluating the Feasibility of Data Simulation for Radiation Research: Estimating RBE Values for HZE Radiation

As the drive for deep space exploration intensifies, a comprehensive understanding of the health effects of radiation exposure becomes paramount to the future of human space flight. However, epidemiological data for radiation exposure, particularly to high-energy (HZE) ions, is limited, partially due to the financial and logistical costs of radiation studies. As an alternative, this study aims to assess the viability of data simulation strategies to accurately model potential study parameters prior to utilizing laboratory conditions. This study estimates a relative biological effectiveness (RBE) factor based on the solid tumor data for outbred mice provided by Edmundson et al. 2020. Excess relative risk (ERR) models for HZE-Fe ions and gamma radiation were estimated using Poisson regression with Weibull models to represent the background solid tumor hazard without radiation. RBE values were calculated from the ratio of the heavy ion linear slope to the gamma linear slope. The parameters from these models were then applied to simulate iterations of 300 datasets across HZE-Fe doses of 0.05, 0.2, 0.4, and 0.75 Gy; gamma radiation doses of 0.75, 2, and 3 Gy, as well as an unirradiated control group. Sample size per dose varied from 100-500 mice across simulations (800-4000 mice total per dataset). 1500 datasets were generated total (300 each for sample sizes 800, 1600, 3200, and 4000). For each dataset, ERR per radiation type and RBE for HZE-Fe were calculated. The RBE from the Edmondson data was calculated to be 5.55. The RBEs from the simulated data converged around this value across the increasing sample sizes. For n = 4000, the mean RBE across the 300 datasets was 5.71 (95% CI: 5.47-5.95). These results suggest that RBEs calculated from simulated data are credible. Based on this exploration, data simulation is a viable method of testing radiation studies. It provides a method of testing study assumptions and refining research questions prior to embarking on costly laboratory experiments.

Sneha Mehta↗

Ionizing radiation-induced mutagenesis: radiation studies in Neurospora predictive for results in mammalian cells

Ionizing radiation was the first mutagen discovered and was used to develop the first mutagenicity assay. In the ensuing 70+ years, ionizing radiation became a fundamental tool in understanding mutagenesis and is still a subject of intensive research. Frederick de Serres et al. developed and used the Neurospora crassa ad-3 system initially to explore the mutagenic effects of ionizing radiation. Using this system, de Serres et al. demonstrated the dependence of the frequency and spectra of mutations induced by ionizing radiation on the dose, dose rate, radiation quality, repair capabilities of the cells, and the target gene employed. This work in Neurospora predicted the subsequent observations of the mutagenic effects of ionizing radiation in mammalian cells. Modeled originally on the mouse specific-locus system developed by William L. Russell, the N. crassa ad-3 system developed by de Serres has itself served as a model for interpreting the results in subsequent systems in mammalian cells. This review describes the primary findings on the nature of ionizing radiation-induced mutagenesis in the N. crassa ad-3 system and the parallel observations made years later in mammalian cells.

NASA Discipline Radiation Health↗

Assessment of NASA GISS CMIP5 and Post-CMIP5 Simulated Clouds and TOA Radiation Budgets Using Satellite Observations: TOA Radiation Budget and CREs - Part 2

In Part I of this study, the NASA GISS Coupled Model Intercomparison Project (CMIP5) and post-CMIP5 (herein called C5 and P5, respectively) simulated cloud properties were assessed utilizing multiple satellite observations, with a particular focus on the southern midlatitudes (SMLs). This study applies the knowledge gained from Part I of this series to evaluate the modeled TOA radiation budgets and cloud radiative effects (CREs) globally using CERES EBAF (CE) satellite observations and the impact of regional cloud properties and water vapor on the TOA radiation budgets. Comparisons revealed that the P5- and C5-simulated global means of clear-sky and all-sky outgoing longwave radiation (OLR) match well with CE observations, while biases are observed regionally. Negative biases are found in both P5- and C5-simulated clear-sky OLR. P5-simulated all-sky albedo slightly increased over the SMLs due to the increase in low-level cloud fraction from the new planetary boundary layer (PBL) scheme. Shortwave, longwave, and net CRE are quantitatively analyzed as well. Regions of strong large-scale atmospheric upwelling/downwelling motion are also defined to compare regional differences across multiple cloud and radiative variables. In general, the P5 and C5 simulations agree with the observations better over the downwelling regime than over the upwelling regime. Comparing the results herein with the cloud property comparisons presented in Part I, the modeled TOA radiation budgets and CREs agree well with the CE observations. These results, combined with results in Part I, have quantitatively estimated how much improvement is found in the P5-simulated cloud and radiative properties, particularly over the SMLs and tropics, due to the implementation of the new PBL and convection schemes.

Model comparison↗

Radiation-induced genomic instability: radiation quality and dose response

Genomic instability is a term used to describe a phenomenon that results in the accumulation of multiple changes required to convert a stable genome of a normal cell to an unstable genome characteristic of a tumor. There has been considerable recent debate concerning the importance of genomic instability in human cancer and its temporal occurrence in the carcinogenic process. Radiation is capable of inducing genomic instability in mammalian cells and instability is thought to be the driving force responsible for radiation carcinogenesis. Genomic instability is characterized by a large collection of diverse endpoints that include large-scale chromosomal rearrangements and aberrations, amplification of genetic material, aneuploidy, micronucleus formation, microsatellite instability, and gene mutation. The capacity of radiation to induce genomic instability depends to a large extent on radiation quality or linear energy transfer (LET) and dose. There appears to be a low dose threshold effect with low LET, beyond which no additional genomic instability is induced. Low doses of both high and low LET radiation are capable of inducing this phenomenon. This report reviews data concerning dose rate effects of high and low LET radiation and their capacity to induce genomic instability assayed by chromosomal aberrations, delayed lethal mutations, micronuclei and apoptosis.

Review↗

Modern Radiation Therapy for Extranodal Nasal-Type NK/T-cell Lymphoma: Risk-Adapted Therapy, Target Volume, and Dose Guidelines from the International Lymphoma Radiation Oncology Group

In the multidisciplinary management of early-stage extranodal natural killer/T-cell lymphoma, nasal type (ENKTCL), with curative intent, radiation therapy is the most efficacious modality and is an essential component of a combined-modality regimen. In the past decade, utilization of upfront radiation therapy and non–anthracycline-based chemotherapy has improved treatment and prognosis. This guideline mainly addresses the heterogeneity of clinical features, principles of risk-adapted therapy, and the role and appropriate design of radiation therapy. Radiation therapy methods (including target volume definition, dose and delivery methods) are crucial for optimizing cure for patients with early-stage ENKTCL. The application of the principles of involved site radiation therapy in this lymphoma entity often leads to a more extended clinical target volume (CTV) than in other lymphoma types because it usually presents with primary tumor invasion, multifocal lesions, or extensive submucosal infiltration beyond the macroscopic disease. The CTV varies across different primary sites and is classified mainly into nasal, nonnasal upper aerodigestive tract (UADT), and extra-UADT entities. This review is a consensus of the International Lymphoma Radiation Oncology Group regarding the approach to radiation therapy, target-volume definition, optimal dose, and dose constraints in ENKTCL treatment.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

Non-targeted and delayed effects of exposure to ionizing radiation: I. Radiation-induced genomic instability and bystander effects in vitro

A long-standing dogma in the radiation sciences is that energy from radiation must be deposited in the cell nucleus to elicit a biological effect. A number of non-targeted, delayed effects of ionizing radiation have been described that challenge this dogma and pose new challenges to evaluating potential hazards associated with radiation exposure. These effects include induced genomic instability and non-targeted bystander effects. The in vitro evidence for non-targeted effects in radiation biology will be reviewed, but the question as to how one extrapolates from these in vitro observations to the risk of radiation-induced adverse health effects such as cancer remains open.

Review, Tutorial↗

Enhanced Cloud Top Longwave Radiative Cooling Due To the Effect of Horizontal Radiative Transfer in the Stratocumulus to Trade Cumulus Transition Regime

Abstract Recent studies develop the SPeedy Algorithm for Radiative TrAnsfer through CloUd Sides (SPARTACUS) to handle the influence of horizontal RT on vertical radiative fluxes within an atmospheric column. The present study applies SPARTACUS to large eddy simulation (LES)‐generated cloud fields across the stratocumulus to trade cumulus transition (STCT) regime with coarse and fine vertical resolutions. The results show that, as the vertical resolution increases, radiation simulations show increasingly stronger cloud‐top longwave (LW) radiative cooling. Consequently, the sharp radiative heating gradient across the cloud layer in the LES‐like resolution simulations cannot be resolved with the coarse resolution simulations. Including the horizontal RT typically enhances cloud LW radiative cooling rate by less than 10% for all the cloud fields but more significantly in the cloud fields during the STCT. The enhanced cloud LW radiative cooling also occurs in the lower cloud layer in the decoupled cumulus cloud regime.

Geology↗

Plasma radiation behavior approaching high-radiation scenarios in W7-X

The W7-X stellarator has so far performed experiments under both limiter and divertor conditions. The plasma is mostly generated by ECR-heating with powers up to 6.5 MW, and the plasma density is usually limited by the radiation losses from low-Z impurities (such as carbon and oxygen) released mainly from the graphite targets. The present work first summarizes the radiation loss fractions f rad achieved in quasi-stationary hydrogen plasmas in both operational phases, and then shows how impurity radiation behaves differently with the two different boundary conditions as the plasma density increases. The divertor operation is emphasized and some beneficial effects (with respect to impurity radiation) are highlighted: (1) intensive radiation is located at the edge (r/a > 0.8) even at high radiation loss fractions, (2) the plasma remains stable up to f rad approaching unity, (3) the reduction in the stored energy is about 10% for high f rad scenarios. Moreover, effects of wall boronisation on impurity radiation profiles are also presented.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

The radiation balance of the earth-atmosphere system from Nimbus 3 radiation measurements

The radiation balance of the earth-atmosphere system and its components was computed from global measurements of radiation reflected and emitted from the earth to space. These measurements were made from the meteorological satellite Nimbus 3 during the periods from April 16 to August 15, 1969; October 3 to 17, 1969; and January 21 to February 3, 1970. Primarily the method of evaluation, its inherent assumptions, and possible error sources were discussed. Results are presented by various methods: (1) global, hemispherical, and zonal averages obtained from measurements in all semimonthly periods and (2) global maps of the absorbed solar radiation, the albedo, the outgoing longwave radiation, and the radiation balance obtained from measurements during semimonthly periods in each season (May 1 to 15, July 16 to 31, and October 3 to 17, 1969, and January 21 to February 3, 1970). Annual global averages of the albedo and of the outgoing longwave radiation were determined. These values balance to within 1 percent the annual global energy input by solar radiation that was computed for a solar constant.

Raschke, E.↗

The generation of transition radiation by relativistic particles in plastic foam radiators

The design of large area transition radiation detectors for highly relativistic particles can be greatly simplified if plastic foam radiators are employed. Using electron beams with energies 1-9 GeV at the Cornell synchrotron, we have studied the properties of a large variety of transition radiators consisting of commercially available foam materials. In most cases, a measurable transition radiation signal has been observed, but only a few materials have been found to be suitable for practical purposes. The observed radiation yield is in these cases very similar to that of equivalent multifoil radiators. A detailed discussion is given of the particle detection efficiency that can be obtained with high yield foam radiators.

Prince, T. A.↗

The effect of directional radiation models on the interpretation of earth radiation budget measurements

A parameter estimation technique is presented to estimate the radiative flux density distribution over the earth from a set of radiometer measurements at satellite altitude. The technique analyzes measurements from a wide field of view, horizon to horizon, nadir pointing sensor with a mathematical technique to derive the radiative flux density estimates at the top of the atmosphere for resolution elements smaller than the sensor field of view. A computer simulation of the data analysis technique is presented for both earth-emitted and reflected radiation. The errors resulting from the assumed directional radiation model, spatial model and random measurement error have little effect on the global mean radiation. Zonal estimates were found to be more sensitive to the spatial model than to the directional radiation model. Results from analyzing medium field of view measurements showed a much greater sensitivity to the directional radiation model even on a global scale.

Green, R. N.↗

Development of a high-performance cryogenic radiator with V-groove radiation shields

A feasibility demonstration model of a new-technology, high-performance, cryogenic radiative cooler has been successfully tested in a helium-cooled vacuum chamber. Thermal isolation of the radiator cold stage from the warm spacecraft and instrument is achieved by a novel arrangement of lightweight radiation shields which form large V-groove cavities, and by the use of low-conductance structural supports. The vacuum chamber experiments demonstrate the thermal isolation capability of the radiator design. Analytical model predictions are all within 1 K of the measured test temperatures. Utilization of this design enables reasonably sized radiative coolers (less than 0.3 sq m) to achieve operating temperatures below 60 K at earth, Mars, and beyond for useful cooling loads below 75 mW. The design can be scaled to accommodate larger heat loads. The reduction in operating temperature of over 15 K relative to any radiative cooler flown in the past will allow the V-groove isolation radiator to meet the challenging instrument cooling requirements of many future space missions.

Bard, Steven↗