Toward a generic subsetting engine
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Monte Carlo studies using population models intended to represent response surface applications are reported. Simulated experiments were generated by adding pseudo random normally distributed errors to population values to generate observations. Model equations were fitted to the observations and the decision procedure was used to delete terms. Comparison of values predicted by the reduced models with the true population values enabled the identification of deletion strategies that are approximately optimal for minimizing prediction errors.
Backward elimination procedure minimizes prediction errors of equations fitted to factorial experiments. Problem of minimizing prediction error solved for two-level full- or fractional-factorial experiment with 16 factorial points and 0 to 6 center points. Such experiment provides 16 orthogonal coefficient estimates for empirical polynomial model. Each coefficient estimated with low variance error estimated from 16 observations.
Near-infrared imaging obtained for systems believed to be advanced disk-disk mergers are presented and discussed. These systems were chosen from a sample of approximately 170 objects from the Arp Atlas of Peculiar Galaxies which have been imaged in the JHK bands as part of an investigation into the stellar component of interacting galaxies. Of the eight remnants which show optical signs of a disk-disk merger, the near-infrared surface brightness profiles are well-fitted by an r exp 1/4 law over all measured radii in four systems, and out to radii of about 3 kpc in three systems. These K band profiles indicate that most of the remnants in the sample either have finished or are in the process of relaxing into a mass distribution like that of normal elliptical galaxies.
About 15 percent of the gamma ray bursts in the Burst and Transient Source Experiment (BATSE) data exhibit a simple light curve consisting mainly of a single pulse without fine substructures. In 12 of the burst profiles, the pulse shapes show a linear rise and decay. Three events have a distinct sharp rise followed by a long, almost exponential decay. Searches based on only a sharp rise selection criterion resulted in five more grbs with different profile complexities. In one case, we identify an envelope of fast oscillations with a long, softer tail lasting about 100 seconds. The majority of events were detectable at energies above 300 keV, with tentative estimates for fluences that vary between 4.0 x 10(exp -8) and 5.4 x 10(exp -6) ergs/sq cm. We describe here their general characteristics (durations, rise-decay times) and their hardness ratios.
A model reduction method is investigated to provide a smaller structural dynamic model for subsequent structural control design. A structural dynamic model is assumed to be derived from finite element analysis. It is first converted into the state space form, and is further reduced by the internal balancing method. Through the co-ordinate transformation derived from the states that are deleted during reduction, the reduced model is finally expressed with the states that are members of the original states. Therefore, the states in the final reduced model represent the degrees of freedom of the nodes that are selected by the designer. The procedure provides a more practical implementation of model reduction for applications in which specific nodes, such as sensor and/or actuator attachment points, are to be retained in the reduced model. Thus, it ensures that the reduced model is under the same input and output condition as the original physical model. The procedure is applied to two simple examples and comparisons are made between the full and reduced order models. The method can be applied to a linear, continuous and time-invariant model of structural dynamics with nonproportional viscous damping.
PURPOSE. To evaluate the tissue-specific expression pattern of the 64kD human autoantigen D1, a tropomodulin-related protein that may be involved in thyroid-associated ophthalmopathy. METHODS. Recombinant 64kD human autoantigen D1 was generated in a bacterial expression system and used to immunize rabbits. Specific antibodies were affinity-purified and used for Western blots on normal and hyperthyroid rat and rabbit tissue, and immunofluorescence localization on cryosections of rat tissue. RESULTS. Anti-64kD human autoantigen D1 antibodies recognize specifically a approximately 70kD polypeptide in western blots of extraocular muscle, sternothyroid muscle, and smooth muscle. Immunofluorescence staining demonstrates that the 64kD human autoantigen D1 localizes to myofibrils in slow fibers from rat extraocular and sternothyroid muscle. The level of this protein is not altered in extraocular muscles from hyperthyroid rabbits. CONCLUSIONS. The 64kD human autoantigen D1 is expressed in slow fibers of extraocular and sternothyroid muscles as a component of myofibrils, and is not upregulated in conditions of hyperthyroidism.
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One of the longest standing questions in network theory is how a component influences other parts in the system, and how that role is affected when restricting the navigation through the network. The Katz score, one of many centrality measures created for this purpose, takes into account all possible walks through the network, penalizing each additional step in a walk by a scalar called the Katz parameter. This centrality measure often covers an infinite number of walks with infinite length. In this paper we identify the maximum path length which has influence on the Katz score. We ultimately provide guidance when deciding which Katz parameter to use as it depends on the path length of interest. We show how changing the Katz parameter affects the ranking of the vertices in some synthetic graphs as well as NASA's expert informed network of medical dependencies called the Susceptibility Inference Network (SIN).
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