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At least 559 records · Page 31

Ultrastructural response of rat lung to 90 days' exposure to oxygen at 450 mm Hg

Young Sprague-Dawley rats were exposed to 100% oxygen at 450 mm Hg in constant environment capsules for 90 days. Lung tissue examined by electron microscopy revealed a number of changes, many similar to those observed after exposure to oxygen at 760 mm Hg for shorter periods of time. Alterations in vesicle size and number and in mitochondrial matrix and cristae appear in both the endothelial and epithelial cells. Blebbing and rarefication of cytoplasm occur in both cell layers of the alveolo-capillary wall. Also seen are fluid in the basement membrane, platelets in the capillaries, and alveolar fluid and debris. All of these alterations occur at 1 atm exposure. However, after exposure to 450 mm Hg the changes are not as widespread nor as destructive as they are at the higher pressure.

Harrison, G. A.↗

Biochemical observation during 28 days of space flight

With the completion of the 28-day flight of Skylab 2, the sum of biochemical data on human reaction to the weightless environment was significantly extended both quantitatively and qualitatively. The biochemical studies were divided into two broad categories. One group included the more routine blood studies similar to those used in everyday medical practice. The second category encompassed those analyses used to investigate more thoroughly the endocrinological and fluid changes first seen in the crewmembers following the Gemini, Apollo, and Soviet missions. Significant biochemical changes were observed that varied in magnitude and direction, but all disappeared shortly after return to earth. Most of changes indicate successful adaptation by the body to the combined stresses of weightlessness. Results of the biochemical observation are presented in the form of data tables and graphs.

Leach, C. S.↗

Interplanetary magnetic field direction and the configuration of the day side magnetosphere

The direction of the interplanetary magnetic field appears to have a significant effect on the equilibrium size of the day side magnetosphere. The qualitative features of this effect are illustrated here by means of a simple vacuum model that ignores solar wind and ionospheric plasma densities as a first approximation. This idealized model produces earthward displacements of the subsolar magnetopause and equatorward displacements of the polar cusp associated with southward-turning interplanetary fields that are about a factor of 2 greater than observed displacements. The nonzero solar wind plasma pressure and ionospheric conductivity produce large deviations from the simple vacuum configurations but do not change the qualitative conclusions regarding magnetopause and cusp displacements associated with the north-south component of the interplanetary magnetic field.

Hill, T. W.↗

+Gz tolerance in man after 14-day bedrest periods with isometric and isotonic exercise conditioning

The effects of isometric and isotonic exercise training on post-bedrest +Gz tolerance were determined. In general, 14-day bedrest resulted in a significant loss of Gz tolerance, as previously discovered. At 2.1 Gz, neither the isometric nor the isotonic exercises regimens resulted in a significant increase in post-bedrest Gz tolerance. However, following isometric exercise, restoration of about half the tolerance decrement occurred at 3.2 Gz and 3.8 Gz. Possible reasons for this partial restoration of tolerance are put forward.

Greenleaf, J. E.↗

Linear polarization variations modulo 5.6 days in HDE 226868

Results are reported for observations of variations in the linear polarization in HDE 226868 (the optical counterpart of Cyg X-1) made with a photoelastic polarimeter and a U-filter. The UV linear-polarization variations, as folded on the 5.6-day orbital period, are found to have amplitudes of 0.25% and position-angle changes of 2.7 deg. These results are shown to be consistent with the geometry and phasing required by the model of the binary system.

Nolt, I. G.↗

Hemodynamics, renal function, plasma renin, and aldosterone in man after 5 to 14 days of bedrest

Continuous bedrest for 5 to 14 days had no significant effect on resting heart rate, blood pressure, or cardiac output in six normal men. Head-up tilt induced greater tachycardia in 5 of 6 patients after bed rest than in the control period. Propranolol diminished both tachycardia and the incidence of hypotension and faintness in upright posture. Plasma volume fell, extracellular fluid volume increased, and plasma renin activity was significantly elevated following bedrest. Unusually large increases in plasma renin followed head-up tilt or administration of isoproterenol during bedrest and after resuming normal activity. During bedrest, plasma aldosterone was often increased in the early morning. It is concluded that after bedrest, upright posture evokes strong beta-adrenergic activity as well as exaggerated metabolic and circulatory responses which can be reduced or abolished by the beta-adrenergic blocker, propranolol.

Melada, G. A.↗

Electromyographic analysis of skeletal muscle changes arising from 9 days of weightlessness in the Apollo-Soyuz space mission

Both integration and frequency analyses of the electromyograms from voluntary contractions were performed in one crewman of the Apollo-Soyuz Test Project mission. Of particular interest were changes in excitability, electrical efficiency, and fatigability. As a result of 9 days of weightlessness, muscle excitability was shown to increase; muscle electrical efficiency was found to decrease in calf muscles and to increase in arm muscles; and fatigability was found to increase significantly, as shown by spectral power shifts into lower frequencies. It was concluded from this study that skeletal muscles are affected by the disuse of weightlessness early in the period of weightlessness, antigravity muscles seem most affected by weightlessness, and exercise may abrogate the weightlessness effect. It was further concluded that electromyography is a sensitive tool for measuring spaceflight muscle effects.

Lafevers, E. V.↗

Possible theoretical explanations for occasional days of non-field-aligned diffusion at neutron monitor energies

It has been shown previously (Anath et al., 1973 and Kane, 1974) that 20 to 25% of days, the diffusion component of the cosmic-ray neutron diurnal anisotropy is directed more than 30 degrees away from the ecliptic projection of the interplanetary magnetic field averaged over the same 24 hours. A number of explanations for this deviation are discussed and it is concluded that transverse gradient drifts due to gradients perpendicular to the ecliptic are likely, that diurnal variations in the diffusion component of the neutron anisotropy may affect results from single stations and that the 24 hour mean interplanetary magnetic field may not be the field appropriate to the streaming equation at neutron monitor energies.

Forman, M. A.↗

Electron angular distributions above the day side auroral oval

An electrostatic analyzer, a Lepedea, was employed on the low-altitude satellite Ariel 4 in order to gain pitch angle distributions of electron intensities with good temporal resolution within the energy range 205 eV to 12.5 keV over the day side auroral oval. Two major precipitation zones were encountered: an equatorward zone of broad spectra with intensities of about 10 to the 4th el/sq cm/s/sr/eV and a poleward zone, the polar cusp, with intensities typical of those of the magnetosheath. Angular distributions within the equatorward zone are generally isotropic outside of the atmospheric backscatter cone. The precipitation mechanism would appear to be pitch angle scattering near the distant magnetic equator. In contrast, pitch angle distributions within the polar cusp are often found to be strongly field aligned with intensities within the atmospheric loss cone greater by factors of about 10 than the mirroring intensities.

Craven, J. D.↗

Spectra of Her X-1 near a turn-on in the 35-day cycle

X-ray spectra for Her X-l are presented for times before, during, and after a turn-on in the 35 day on-off cycle, as well as during an anomalous dip in the X-ray intensity. All four spectra are well represented by a power law of number index approximately .9 with a high energy cutoff near 20 keV. However, the column density of cold matter along the line of sight as estimated by the low energy cutoff varies substantially among the four intervals. The low level flux present prior to turn-on does not pulse and shows very little low energy absorption, in contrast to the X-rays observed during the turn-on and the anomalous dip. It seems likely that the pre-turn-on flux is composed of X-rays scattered into the line of sight by material away from the accretion disk.

Becker, R. H.↗

Spectral line similarity in the geomagnetic dipole field variations and length of day fluctuations

Power spectral density analysis using Burg's maximum entropy method (MEM) was applied to the geomagnetic dipole field and its rate of change for the years 1901-1969. Both spectra indicate relative maxima at 0.015 cycle/yr and its harmonics. These maxima correspond approximately to 66-, 33-, 22-, 17-, 13-, 11-, and 9-year spectral lines. The application of the same analysis techniques to the length of day (l.o.d.) fluctuations for the period 1865-1961 reveals similar spectral characteristics. The existence of the common spectral peaks with periods of 66 and 33 years in the l.o.d. fluctuations and the geomagnetic dipole field is clearly established. The existence of the higher harmonics is somewhat uncertain because of the line-splitting problem in the MEM spectral analysis. It is suggested that the spectral line similarity in the l.o.d. fluctuations and the dipole field variations is related to the motion within the earth's fluid core during the past 100 years.

Jin, R.-S.↗

Strength and rigidity of the elastic lunar lithosphere and implications for present-day mantle convection in the moon

Lunar gravity data are used to estimate the thickness of the elastically defined lunar lithosphere, and the load-bearing capability of lithosphere with respect to lunar mascons is analyzed by representing the elastic lithosphere as a plane elastic plate subject to spatially concentrated loads from above and buoyant support from below. Gravity perturbations are computed and compared with observations, the spectrum of lunar gravity perturbations is derived, and effects of curvature are considered. The magnitude of the elastic stresses associated with a lithospheric flexure model maintaining the irregularities of the lunar gravity field is shown to be quite similar to that of the lithospheric stresses found on earth. It is concluded that associated differences in gravity, heat flow, and lithospheric thickness all combine to make the lunar lithosphere much more rigid and stronger than that of earth. Implications for present-day lunar convection are discussed.

Kuckes, A. F.↗

Spectra of Hercules X-1 near a turn-on in the 35 day cycle

X-ray spectra for Her X-1 are presented for times before, during, and after a turn-on in the 35 day on-off cycle, as well as during an anomalous dip in the X-ray intensity. All four spectra are well represented by a power law of number index 0.9 with a high-energy cutoff near 20 keV. However, the column density of cold matter along the line of sight as estimated by the low-energy cutoff varies substantially among the four intervals. The low level flux present prior to turn-on was not seen to pulse and showed very little low-energy absorption, in contrast to the X-rays observed during the turn-on and the anomalous dip. It seems likely that the pre-turn-on flux is composed of X-rays scattered into the line of sight by material away from the accretion disk. An accurate determination of the pulsation period for Her X-1 during 1975 August finds the period has decreased to 1.2378065 plus or minus 0.0000001 s.

Becker, R. H.↗

Structural and Functional Organization of the Vestibular Apparatus in Rats Subjected to Weightlessness for 19.5 Days Aboard the Kosmos-782 Satellite

The vestibular apparatus was investigated in rats subjected to weightlessness for 19.5 days. The vestibular apparatus was removed and its sections were fixed in a glutaraldehyde solution for investigation by light and electron microscopes. Structural and functional charges were noted in the otolith portions of the ear, with the otolith particles clinging to the utricular receptor surface and with the peripheral arrangement of the nucleolus in the nuclei of the receptor cells. It is possible that increased edema of the vestibular tissue resulted in the destruction of some receptor cells and in changes in the form and structure of the otolith. In the horizontal crista, the capula was separated.

Vinnikov, Y. A.↗

Effect of 6-day hypokinesia on oxygen metabolism indices in elderly and senile subjects

After a strict 6 day confinement to bed of elderly and senile subjects the oxygen supply of the subcutaneous cellular tissue was impaired, and the intensity of its tissue respiration was somewhat reduced. The vacat-oxygen of the blood and urine, the coefficient of incomplete oxidation, and the oxygen deficiency in the organism were increased.

Ivanov, L. A.↗

Continuous 30-day measurements utilizing the monkey metabolism pod

A fiberglass system was previously described, using which quantitative physiological measurements could be made to study the effects of weightlessness on 10 to 14 kg adult monkeys maintained in comfortable restraint under space flight conditions. Recent improvements in the system have made it possible to obtain continuous measurements of respiratory gas exchange, cardiovascular function, and mineral balance for periods of up to 30 days on pig-tailed monkeys. It has also been possible to operate two pods which share one set of instrumentation, thereby permitting simultaneous measurements to be made on two animals by commutating signal outputs from the pods. In principle, more than two pods could be operated in this fashion. The system is compatible with Spacelab design. Representative physiological data from ground tests of the system are presented.

Pace, N.↗

The 78.4 day period of Cygnus XR-1

A search for a 78.4 day modulation in the high energy X-ray flux observed with OSO-8 and in the U-band optical polarization is reported. It is suggested that if such a modulation does exist, it is more likely to be related to the rotation of the free modes of oscillation of the primary than to the existence of a third body in the system.

Dolan, J. F.↗