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At least 559 records · Page 31

Geometry planning and image registration in magnetic particle imaging using bimodal fiducial markers

Purpose: Magnetic particle imaging (MPI) is a quantitative imaging modality that allows the distribution of superparamagnetic nanoparticles to be visualized. Compared to other imaging techniques like x-ray radiography, computed tomography (CT), and magnetic resonance imaging (MRI), MPI only provides a signal from the administered tracer, but no additional morphological information, which complicates geometry planning and the interpretation of MP images. The purpose of the authors’ study was to develop bimodal fiducial markers that can be visualized by MPI and MRI in order to create MP–MR fusion images. Methods: A certain arrangement of three bimodal fiducial markers was developed and used in a combined MRI/MPI phantom and also during in vivo experiments in order to investigate its suitability for geometry planning and image fusion. An algorithm for automated marker extraction in both MR and MP images and rigid registration was established. Results: The developed bimodal fiducial markers can be visualized by MRI and MPI and allow for geometry planning as well as automated registration and fusion of MR–MP images. Conclusions: To date, exact positioning of the object to be imaged within the field of view (FOV) and the assignment of reconstructed MPI signals to corresponding morphological regions has been difficult. The developed bimodal fiducial markers and the automated image registration algorithm help to overcome these difficulties.

60 APPLIED LIFE SCIENCES↗

Auroral energy deposition rate, characteristic electron energy, and ionospheric parameters derived from Dynamics Explorer 1 images

Auroral images obtained by the Spin Scan Auroral Imager (SAI) aboard the DE-1 satellite were used to derive auroral energy deposition rate, characteristic electron energy, and ionospheric parameters. The principles involved in the imaging technique and the physical mechanisms that underlie the relationship between the spectral images and the geophysical parameters are discussed together with the methodology for implementing such analyses. It is shown that images obtained with the SAI provide global parameters at 12-min temporal resolution; the spatial resolution is limited by the field of view of a pixel. The analysis of the 12-min images presented yielded a representation of ionospheric parameters that was better than can be obtained using empirical models based on local measurements averaged over long periods of time.

Rees, M. H.↗

Flow Visualization of Aircraft in Flight by Means of Background Oriented Schlieren Using Celestial Objects

The Background Oriented Schlieren using Celestial Objects series of flights was undertaken in the spring of 2016 at National Aeronautics and Space Administration Armstrong Flight Research Center to further develop and improve a flow visualization technique which can be performed from the ground upon flying aircraft. Improved hardware and imaging techniques from previous schlieren tests were investigated. A United States Air Force T-38C and NASA B200 King Air aircraft were imaged eclipsing the sun at ranges varying from 2 to 6 nautical miles, at subsonic and supersonic speeds.

schlieren photography↗

35-45 Giga Hertz Transceiver System for Phase and Magnitude Detection

Nondestructive evaluation (NDE) is the science and practice of examining an object in a way that the object's usefulness is not adversely affected. Different types of NDE methods exist but this thesis is based on microwave and millimeter wave NDE using imaging techniques. Microwave NDE is based on illuminating the object under test with a microwave signal and studying the various properties of the reflected signal from the object. This reflected signal contains some information about the inner structure of the object under test. This information may be contained in several parameters including the phase and magnitude of the reflected signal. The goal of this project is to design and build a Q-band coherent transceiver that is capable of measuring the reflected signal's phase and magnitude so that an image of the object under test may be reconstructed. From the several techniques that can be used to construct an image of the object under test, techniques of interest to this work include synthetic aperture focusing technique (SAFT) and microwave holography. The transceiver system should have the ability to sweep a large portion of Q-band frequency range in small frequency steps as quick as possible while the detected phase and magnitude of the reflected signal is very accurate. Several different designs were studied and the final schematic diagram of the transceiver system was determined. One of the most important modules that was designed, implemented and tested in the laboratory was an accurate phase/magnitude detector circuit. The compared results of the scans using the transceiver system and vector network analyzer (VNA) showed that this transceiver system has a great potential to replace a VNA for the purpose of microwave and millimeter wave imaging.

Beni, Aman Aflaki↗

Imaging for dismantlement verification: information management and analysis algorithms

The level of detail discernible in imaging techniques has generally excluded them from consideration as verification tools in inspection regimes. An image will almost certainly contain highly sensitive information, and storing a comparison image will almost certainly violate a cardinal principle of information barriers: that no sensitive information be stored in the system. To overcome this problem, some features of the image might be reduced to a few parameters suitable for definition as an attribute, which must be non-sensitive to be acceptable in an Information Barrier regime. However, this process must be performed with care. Features like the perimeter, area, and intensity of an object, for example, might reveal sensitive information. Any data-reduction technique must provide sufficient information to discriminate a real object from a spoofed or incorrect one, while avoiding disclosure (or storage) of any sensitive object qualities. Ultimately, algorithms are intended to provide only a yes/no response verifying the presence of features in the image. We discuss the utility of imaging for arms control applications and present three image-based verification algorithms in this context. The algorithms reduce full image information to non-sensitive feature information, in a process that is intended to enable verification while eliminating the possibility of image reconstruction. The underlying images can be highly detailed, since they are dynamically generated behind an information barrier. We consider the use of active (conventional) radiography alone and in tandem with passive (auto) radiography. We study these algorithms in terms of technical performance in image analysis and application to an information barrier scheme.

98 NUCLEAR DISARMAMENT, SAFEGUARDS, AND PHYSICAL P↗

Introduction: Photons and Ground-Based

A Conference on Measurement Techniques for Solar and Space Physics was held on 20-24 April 2015 in Boulder, Colorado, at the National Center for Atmospheric Research Center Green Campus. The present volume collects together the conference papers for photons and ground-based categories. This gathering of over 200 scientists and instrumentalists was born out of the desire to collect in one place the latest experiment and instrument technologies required for advancement of scientific knowledge in the disciplines of solar and space physics. The two goals for this conference and the subsequent publication of its content are (a) to describe measurement techniques and technology development needed to advance high priority science in the fields of solar and space physics; and (b) to provide a survey or reference of techniques for in situ measurement and remote sensing of space plasmas. Towards this end, our goal has always been inspired by the two 1998 Geophysical Monographs (Nos. 102 and 103) entitled, "Measurement Techniques in Space Plasmas" (particles and fields) [Pfaff et al., 1998a, 1998b], which have served as a reference and resource for advanced students, engineers, and scientists who wish to learn the fundamentals of measurement techniques and technology in this field. Those monographs were the product of an American Geophysical Union Chapman Conference that took place in Santa Fe, NM, in 1995: "Measurement Techniques in Space Plasmas-What Works, What Doesn't." Two decades later, we believe that it is appropriate to revisit this subject, in light of recent advances in technology, research platforms, and analysis techniques. Moreover, we now include direct measurements of neutral gases in the upper atmosphere, optical imaging techniques, and remote observations in space and on the ground. Accordingly, the workshop was organized among four areas of measurement techniques: particles, fields, photons, and ground-based. This two-set volume is largely composed of the content of that workshop. Special attention is given to those techniques and technologies that demonstrate promise of significant advancement in measurements that will enable the highest priority science as described in the 2012 National Research Council Decadal Survey [Baker and Zurbuchen et al., 2013]. Additionally, a broad tutorial survey of the current technologies is provided to serve as reference material and as a basis from which advanced and innovative ideas can be discussed and pursued. Included are instrumentation and techniques to observe the solar environment from its interior to its outer atmosphere, the heliosphere out to the interstellar regions, in geospace, and other planetary magnetospheres and atmospheres. To make significant progress in priority science as expressed in the National Research Council solar and space physics decadal survey and recent NASA Heliophysics roadmaps, identification of enabling new measurement techniques and technologies to be developed is required. Also, it is valuable to the community and future scientists and engineers to have a complete survey of the techniques and technologies used by the practitioners of solar and space physics. As with the 1995 conference and subsequent 1998 publication, it is incumbent on the community to identify those measurements that are particularly challenging and still require new techniques to be identified and tested to enable the necessary accuracy and resolution of certain parameters to be achieved. The following is a partial list of the measurement technique categories that are featured in these special publications: Particles; Thermal plasma to MeV energetic particles, neutral gas properties including winds, density, temperature, and composition, and enhanced neutral atom imaging; Fields; DC electric and magnetic fields, plasma waves, and electron drift instruments from which the plasma velocity information provides a measure of the DC electric field; Photons; Instruments sensitive from the near-infrared to X-rays; Contributions of techniques and technology for optical design, optical components, sensors, material selection for cameras, telescopes, and spectrographs; Ground based; Remote sensing methods for solar and geospace activity and space weather. The focus includes solar observatories, all-sky cameras, lidars, and ionosphere thermosphere mesosphere observatory systems such as radars, ionosondes, GPS receivers, magnetometers, conjugate observations, and airborne campaigns. The present volume collects together the papers for photons and ground-based categories. The companion volume collects together the papers for particles and fields categories. It is recognized that there are measurement techniques that overlap among the four categories. For example, use of microchannel plate detectors is used in photon and particle measurement techniques or the observation of visible photons and magnetic fields in space and on the ground share common technologies. Therefore, the reader should consider the entire collection of papers as they seek to understand particular applications. We hope that these volumes will be as valuable as a reference for our community as the earlier 1998 volumes have been.

Spann, James↗

Weekly Update - Flat Panel Detector Procurement

The Neutron Imaging (NI) project has procured a Flat Panel Detector (FPD), which will allow multimodal imaging and high-quality CT imaging of dense objects. The FPD will provide a test bed for new scintillator formulations as well as new imaging techniques designed to improve the spatial resolution with which dense objects can be imaged.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

Fatigue-Crack Detection and Monitoring through the Scattered-Wave Two-Dimensional Cross-Correlation Imaging Method Using Piezoelectric Transducers

Piezoelectric transducers are convenient enablers for generating and receiving Lamb waves for damage detection. Fatigue cracks are one of the most common causes for the failure of metallic structures. Increasing emphasis on the integrity of critical structures creates an urgent need to monitor structures and to detect cracks at an early stage to prevent catastrophic failures. This paper presents a two-dimensional (2D) cross-correlation imaging technique that can not only detect a fatigue crack but can also precisely image the fatigue cracks in metallic structures. The imaging method was based on the cross-correlation algorithm that uses incident waves and the crack-scattered waves of all directions to generate the crack image. Fatigue testing for crack generation was then conducted in both an aluminum plate and a stainless-steel plate. Piezoelectric wafer transducer was used to actuate the interrogating Lamb wave. To obtain the scattered waves as well as the incident waves, a scanning laser Doppler vibrometer was adopted for acquiring time-space multidimensional wavefield, followed with frequency-wavenumber processing. The proof-of-concept study was conducted in an aluminum plate with a hairline fatigue crack. A frequency-wavenumber filtering method was used to obtain the incident wave and the scattered wave wavefields for the cross-correlation imaging. After this, the imaging method was applied to evaluate cracks on a stainless-steel plate generated during fatigue loading tests. The presented imaging method showed successful inspection and quantification results of the crack and its growth.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Advanced Optical Diagnostic Methods for Describing Fuel Injection and Combustion Flowfield Phenomena

Over the past decade advanced optical diagnostic techniques have evolved and matured to a point where they are now widely applied in the interrogation of high pressure combusting flows. At NASA Glenn Research Center (GRC), imaging techniques have been used successfully in on-going work to develop the next generation of commercial aircraft gas turbine combustors. This work has centered on providing a means by which researchers and designers can obtain direct visual observation and measurements of the fuel injection/mixing/combustion processes and combustor flowfield in two- and three-dimensional views at actual operational conditions. Obtaining a thorough understanding of the chemical and physical processes at the extreme operating conditions of the next generation of combustors is critical to reducing emissions and increasing fuel efficiency. To accomplish this and other tasks, the diagnostic team at GRC has designed and constructed optically accessible, high pressurer high temperature flame tubes and sectar rigs capable of optically probing the 20-60 atm flowfields of these aero-combustors. Among the techniques employed at GRC are planar laser-induced fluorescence (PLIF) for imaging molecular species as well as liquid and gaseous fuel; planar light scattering (PLS) for imaging fuel sprays and droplets; and spontaneous Raman scattering for species and temperature measurement. Using these techniques, optical measurements never before possible have been made in the actual environments of liquid fueled gas turbines. 2-D mapping of such parameters as species (e.g. OH-, NO and kerosene-based jet fuel) distribution, injector spray angle, and fuel/air distribution are just some of the measurements that are now routinely made. Optical imaging has also provided prompt feedback to researchers regarding the effects of changes in the fuel injector configuration on both combustor performance and flowfield character. Several injector design modifications and improvements have resulted from this feedback. Alternate diagnostic methods are constantly being evaluated as to their suitability as a diagnostic tool in these environments. A new method currently under examination is background oriented Schlieren (BOS) for examining the fuel/air mixing processes. While ratioing the Stokes and anti-Stokes nitrogen lines obtained from spontaneous Raman is being refined for temperature measurement. While the primary focus of the GRC diagnostic work remains optical species measurement and flow stream characterization, an increased emphasis has been placed on our involvement in flame code validation efforts. A functional combustor code should shorten and streamline future combustor design. Quantitative measurements of flow parameters such as temperature, species concentration, drop size and velocity using such methods as Raman and phase Doppler anemometry will provide data necessary in this effort.

Locke, Randy J.↗

Real-time damage characterization for GFRCs using high-speed synchrotron X-ray phase contrast imaging

Here, we report the application of high-speed synchrotron X-ray phase contrast imaging (PCI) in real-time damage characterization for glass fiber reinforced composites (GFRCs) subjected to dynamic loading. Dynamic single-edge notched bending (DSENB) experiments on pre-notched S-2 GFRCs were performed on a modified Kolsky compression bar. During loading, the synchrotron X-ray beam penetrated through the composite specimen from the side to detect damage evolution inside the material. Entire dynamic events were recorded by a high-speed camera as image sequences.0° and 90° unidirectional and cross-ply composites were investigated. An optical imaging technique was also employed to capture similar dynamic events in comparison with the radiographic imaging. It is demonstrated that high-speed X-ray PCI had sufficient phase contrast to characterize a crack initiation at a 20-μm spatial resolution within 920 ns and track the crack geometry during propagation, thereby providing reliable data to quantify the dynamic damage resistance of GFRCs. Furthermore, being capable of recognizing microscopic damage-related features at a sub-10-μm resolution, high-speed X-ray PCI provided fundamental material failure mechanisms to reveal the essential of macroscale structural failure of composites. It can also track the damage evolution inside and between individual plies of laminated composites. However, current high-speed X-ray PCI technique only supports in-situ observation and the high timing and spatial resolutions are limited within a field of view of ~2.5 mm in square, preventing its application in the three-dimensional and larger-area damage detection for GFRC structures.

42 ENGINEERING↗

PyPhase – a Python package for X-ray phase imaging

X-ray propagation-based imaging techniques are well established at synchrotron radiation and laboratory sources. However, most reconstruction algorithms for such image modalities, also known as phase-retrieval algorithms, have been developed specifically for one instrument by and for experts, making the development and diffusion of such techniques difficult. Here, PyPhase, a free and open-source package for propagation-based near-field phase reconstructions, which is distributed under the CeCILL license, is presented. PyPhase implements some of the most popular phase-retrieval algorithms in a highly modular framework supporting its deployment on large-scale computing facilities. This makes the integration, the development of new phase-retrieval algorithms, and the deployment on different computing infrastructures straightforward. Its capabilities and simplicity are presented by application to data acquired at the synchrotron source MAX IV (Lund, Sweden).

36 MATERIALS SCIENCE↗

Imaging inflammation in atherosclerotic plaques: Just make it easy!

The presence of inflammatory cells is a hallmark of unstable atherosclerotic plaques. Several imaging approaches have been developed for the noninvasive detection of inflammatory activities in atherosclerotic plaques. Positron emission tomography (PET) imaging with the injection of 18F-fluorodeoxyglucose (FDG) is currently the most widely used imaging technique to evaluate the density of activated macrophages in atherosclerotic plaques. Nevertheless, FDG-PET imaging has logistical and technical constraints that represent an important obstacle to the wider use of this approach for the evaluation of patients with atherosclerosis. In a similar way as in the oncological field, the balance between the benefits and costs of new drugs need to be improved in patients with cardiovascular diseases. PET imaging of plaque inflammation might represent a very useful tool to identify patients who could benefit the most from anti-inflammatory treatments and to exclude patients with other causes of inflammation who are the most likely to develop severe side effects under these drugs. The availability of radiotracers targeting more specifically inflammation in atherosclerotic plaques would greatly facilitate the logistic organization of this imaging and help to expand the use of PET for the evaluation of atherosclerotic patients.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

Direct imaging of LaAlO{sub 3}/SrTiO{sub 3} nanostructures using piezoresponse force microscopy

The interface between LaAlO{sub 3} and TiO{sub 2}-terminated SrTiO{sub 3} can be switched between metastable conductive and insulating states using a conductive atomic force microscope probe. Determination of the nanoscale dimensions has previously required a destructive readout (e.g., local restoration of an insulating state). Here it is shown that high-resolution non-destructive imaging of conductive nanostructures can be achieved using a specific piezoresponse force microscopy (PFM) technique. Images of conductive and insulating nanoscale features are achieved with feature sizes as small as 30 nm. The measured nanowire width from PFM is well correlated with those obtained from nanowire erasure.

36 MATERIALS SCIENCE↗

Enhancing Diagnosis through AI-driven Analysis of Reflectance Confocal Microscopy

Reflectance Confocal Microscopy (RCM) is a non-invasive imaging technique used in biomedical research and clinical dermatology. It provides virtual high-resolution images of the skin and superficial tissues, reducing the need for physical biopsies. RCM employs a laser light source to illuminate the tissue, capturing the reflected light to generate detailed images of microscopic structures at various depths. Recent studies explored AI and machine learning, particularly CNNs, for analyzing RCM images. Our study proposes a segmentation strategy based on textural features to identify clinically significant regions, empowering dermatologists in effective image interpretation and boosting diagnostic confidence. This approach promises to advance dermatological diagnosis and treatment.

Yoon, Hong-Jun↗

SU-F-I-14: 3D Breast Digital Phantom for XACT Imaging

Purpose: The X-ray induced acoustic computed tomography (XACT) is a new imaging modality which combines X-ray contrast and high ultrasonic resolution in a single modality. Using XACT in breast imaging, a 3D breast volume can be imaged by only one pulsed X-ray radiation, which could dramatically reduce the imaging dose for patients undergoing breast cancer screening and diagnosis. A 3D digital phantom that contains both X-ray properties and acoustic properties of different tissue types is indeed needed for developing and optimizing the XACT system. The purpose of this study is to offer a realistic breast digital phantom as a valuable tool for improving breast XACT imaging techniques and potentially leading to better diagnostic outcomes. Methods: A series of breast CT images along the coronal plane from a patient who has breast calcifications are used as the source images. A HU value based segmentation algorithm is employed to identify breast tissues in five categories, namely the skin tissue, fat tissue, glandular tissue, chest bone and calcifications. For each pixel, the dose related parameters, such as material components and density, and acoustic related parameters, such as frequency-dependent acoustic attenuation coefficient and bandwidth, are assigned based on tissue types. Meanwhile, other parameters which are used in sound propagation, including the sound speed, thermal expansion coefficient, and heat capacity are also assigned to each tissue. Results: A series of 2D tissue type image is acquired first and the 3D digital breast phantom is obtained by using commercial 3D reconstruction software. When giving specific settings including dose depositions and ultrasound center frequency, the X-ray induced initial pressure rise can be calculated accordingly. Conclusion: The proposed 3D breast digital phantom represents a realistic breast anatomic structure and provides a valuable tool for developing and evaluating the system performance for XACT.

60 APPLIED LIFE SCIENCES↗

Dynamically Reconfigurable Data Readout of Pixel Detectors for Automatic Synchronization with Data Acquisition Systems

Reconfigurable detectors with dynamically selectable sensing and readout modes are highly desirable for implementing edge computing as well as enabling advanced imaging techniques such as foveation. The concept of a camera system capable of simultaneous passive imaging and dynamic ranging in different regions of the detector is presented. Such an adaptive-autonomous detector with both spatial and temporal control requires programmable window of exposure (time frames), ability to switch between readout modes such as full-frame imaging and zero-suppressed data, modification of the number of pixel data bits and independent programmability for distinct detector regions. In this work, a method is presented for seamlessly changing time frames and readout modes without data corruption while still ensuring that the data acquisition system (DAQ) does not need to stop and resynchronize at each change of setting, thus avoiding significant dead time. Data throughput is maximized by using a minimum unique data format, rather than lengthy frame headers, to differentiate between consecutive frames. A data control and transmitter (DCT) synchronizes data transfer from the pixel to the periphery, reconfigures the data to transmit it serially off-chip, while providing optimized decision support based on a DAQ definable mode. Measurements on a test structure demonstrate that the DCT can operate at 1 GHz in a 65 nm LP CMOS process.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗