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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 559 records · Page 31
All sourcesNASA NTRSDOE OSTI
NASA NTRS1982

Dielectric and permeability

Using the unabridged Maxwell equations (including vectors D, E and H) new effects in collisionless plasmas are uncovered. In a steady state, it is found that spatially varying energy density of the electric field (E perpendicular) orthogonal to B produces electric current leading, under certain conditions, to the relationship P perpendicular+B(2)/8 pi-epsilon E perpendicular(2)/8 pi = constant, where epsilon is the dielectric constant of the plasma for fields orthogonal to B. In steady state quasi-two-dimensional flows in plasmas, a general relationship between the components of electric field parallel and perpendicular to B is found. These effects are significant in goephysical and astrophysical plasmas. The general conditions for a steady state in collisionless plasma are deduced. With time variations in a plasma, slow compared to ion-gyroperiod, there is a general current, (j*), which includes the well-known polarisation current, given by J*=d/dt (ExM)+(PxB)xB B(-2) where M and P are the magnetization and polarization vectors respectively.

Cole, K. D.↗
NASA NTRS2001

A Single-Vector Force Calibration Method Featuring the Modern Design of Experiments

This paper proposes a new concept in force balance calibration. An overview of the state-of-the-art in force balance calibration is provided with emphasis on both the load application system and the experimental design philosophy. Limitations of current systems are detailed in the areas of data quality and productivity. A unique calibration loading system integrated with formal experimental design techniques has been developed and designated as the Single-Vector Balance Calibration System (SVS). This new concept addresses the limitations of current systems. The development of a quadratic and cubic calibration design is presented. Results from experimental testing are compared and contrasted with conventional calibration systems. Analyses of data are provided that demonstrate the feasibility of this concept and provide new insights into balance calibration.

Parker, P. A.↗
DOE OSTI2020

A Virtual Space Vector Model Predictive Control for a Seven-Level Hybrid Multilevel Converter

This paper proposes a virtual space vector (VSV) model predictive control (MPC) for a three-phase seven-level (7L) hybrid multilevel converter (HMC), where each phase consists of an active-neutral-point-clamped converter with a floating H-bridge. To achieve the best current tracking, which is the primary goal of the proposed algorithm, a novel geometrical positioning approach is proposed to select the optimal voltage vector among all the realspace vectors and VSVs. Then, all the possible switching sequences that belong to the optimal voltage vector are evaluated to realize the dc capacitor voltage balancing and common-mode voltage reduction. Through an external modulator, the optimal voltage vector can be synthesized by using either one-, three-, or seven-segment switching sequence. Compared with the conventional MPC, the proposed VSV-MPC can reduce not only the computational burden but also the current THD. Both simulation and experimental results obtained on silicon carbide based 7L-HMC prototype are presented to validate the feasibility and effectiveness of the proposed VSVMPC strategy.

42 ENGINEERING↗
DOE OSTI2020

Nanoparticles for targeted cancer radiotherapy

Radiotherapy, where ionizing radiation is locally delivered either through an external beam or by surgically implanting radionuclide-based seeds in the tumor, is one of the gold standard treatments for cancer. Due to the non-selective nature of radiation, healthy tissue surrounding the cancerous region is usually affected by the treatment. Hence, new strategies, including targeted alpha therapy, are being studied to improve the selectivity of the treatment and minimize side effects. Several challenges, however, limit the current development of targeted radiotherapy, such as the functionalization of the therapeutic agent with targeting vectors and controlling the release of recoiling daughters. Nanoparticles offer unique opportunities as drug delivery vehicles, since they are biocompatible, enhance the cellular uptake of drugs, and are easily functionalized with targeting molecules. In this review, we examine how nanoparticles can be used for targeted radiotherapy, either as sensitizers of external beams or as delivery vehicles for therapeutic radionuclides. Further, we describe the clinical relevance of different types of nanoparticles, followed by an analysis of how these nanoconstructs can solve some of the main limitations of conventional radiotherapy. Finally, we critically discuss the current situation of nanoparticle-based radiotherapy in clinical settings and challenges that need to be overcome in the future for further development of the field.

62 RADIOLOGY AND NUCLEAR MEDICINE↗
DOE OSTI2014

Asymmetric evolution of magnetic reconnection in collisionless accretion disk

An evolution of a magnetic reconnection in a collisionless accretion disk is investigated using a 2.5 dimensional hybrid code simulation. In astrophysical disks, magnetorotational instability (MRI) is considered to play an important role by generating turbulence in the disk and contributes to an effective angular momentum transport through a turbulent viscosity. Magnetic reconnection, on the other hand, also plays an important role on the evolution of the disk through a dissipation of a magnetic field enhanced by a dynamo effect of MRI. In this study, we developed a hybrid code to calculate an evolution of a differentially rotating system. With this code, we first confirmed a linear growth of MRI. We also investigated a behavior of a particular structure of a current sheet, which would exist in the turbulence in the disk. From the calculation of the magnetic reconnection, we found an asymmetric structure in the out-of-plane magnetic field during the evolution of reconnection, which can be understood by a coupling of the Hall effect and the differential rotation. We also found a migration of X-point whose direction is determined only by an initial sign of J{sub 0}×Ω{sub 0}, where J{sub 0} is the initial current density in the neutral sheet and Ω{sub 0} is the rotational vector of the background Keplerian rotation. Associated with the migration of X-point, we also found a significant enhancement of the perpendicular magnetic field compared to an ordinary MRI. MRI-Magnetic reconnection coupling and the resulting magnetic field enhancement can be an effective process to sustain a strong turbulence in the accretion disk and to a transport of angular momentum.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗
DOE OSTI2019

Λ and Λ ¯ spin interaction with meson fields generated by the baryon current in high energy nuclear collisions

We propose a dynamical mechanism which provides an interaction between the spins of hyperons and antihyperons and the vorticity of the baryon current in noncentral high energy nuclear collisions. The interaction is mediated by massive vector and scalar bosons, which is well known to describe the nuclear spin-orbit force. It follows from the Foldy-Wouthuysen transformation and leads to a strong-interaction Zeeman effect. The interaction may explain the difference in polarizations of Λ and Λ¯ hyperons as measured by the STAR Collaboration at the BNL Relativistic Heavy Ion Collider. Here, the signs and magnitudes of the meson-baryon couplings are closely connected to the binding energies of hypernuclei and to the abundance of hyperons in neutron stars.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗
DOE OSTI2024

Implementation of a Doppler-Free Saturation Spectroscopy (DFSS) Diagnostic for Helicon Wave Electric Field Vector Measurement in Edge Plasma in DIII-D

A laser-based technique known as Doppler-free saturation spectroscopy (DFSS) has been designed, fabricated, and installed on the DIII-D National Fusion Facility to measure the helicon wave electric field vector in the edge plasma. These experimental measurements quantify phenomena resulting in decreased current drive efficiency due to wave/edge plasma interactions. This implementation of DFSS on DIII-D is the first of its kind on a tokamak and thus presents unique engineering challenges, including integration of the system onto an existing multidiagnostic port flange without impacts to system serviceability, as well as maintaining precise laser alignment over a 2-m distance during disruptions and thermal drift of the vessel. Further, these challenges were resolved using innovative design approaches such as a novel decoupled shutter system to facilitate serviceability of the in-vessel mirror assemblies without the need for personnel vessel entry, as well as an ex-vessel piezo-mirror-based optical system for laser beam shaping and real-time steering of the measurement location. The solutions to these engineering challenges were demonstrated during the successful installation and operation of these diagnostic components during the 2022 DIII-D vent and subsequent experimental campaign.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗
DOE OSTI2026

An mRNA vaccine encoding the Ebola virus glycoprotein induces high neutralizing antibody titers and provides strong protection against lethal infections in mouse models

Ebola virus (EBOV) is the causative agent of Ebola disease (EBOD), a viral hemorrhagic fever with a notably high case fatality rate. Current treatments for EBOD are limited to monoclonal antibodies or two licensed viral vector vaccines, a recombinant vesicular stomatitis virus (rVSV)-vectored vaccine or an adenovirus and modified vaccinia Ankara regimen. However, comparisons of protection, efficacy, and durability with alternative nucleotide platforms remain understudied. Here, we evaluated the immunogenicity of an mRNA vaccine expressing the EBOV glycoprotein (GP) in parallel with rVSV- and DNA-based vaccine platforms. The mRNA EBOV-GP vaccine, formulated in lipid nanoparticles, elicited significantly higher levels of total IgG and neutralizing antibody titers compared to the rVSV-EBOV-GP vaccine. Linear antibody epitope analysis indicated a preference for targeting the mucin-like domain in EBOV-GP1 following rVSV-based vaccination, while the mRNA platform distinctly targeted the internal fusion loop of EBOV-GP2. After characterizing the immunogenicity of the mRNA vaccine, two models of EBOD were used to demonstrate its protective efficacy: a surrogate rVSV-based challenge model of EBOD using type-I interferon deficient C57BL/6 mice and infection of BALB/c mice with authentic mouse-adapted EBOV. In both studies, the EBOV mRNA vaccine fully protected the mouse cohorts against morbidity and mortality. Additionally, the EBOV mRNA vaccine produced greater neutralizing antibody titers compared to the DNA EBOV-GP vaccine. These results suggest that an mRNA vaccine expressing EBOV-GP can induce robust, functional humoral responses that are protective against EBOD, warranting further development as an alternative to, or as part of a vaccine strategy including, viral vectored vaccines.

DNA vaccines↗
DOE OSTI2022

Development of radiopharmaceuticals for targeted alpha therapy: Where do we stand?

Targeted alpha therapy is an oncological treatment, where cytotoxic doses of alpha radiation are locally delivered to tumor cells, while the surrounding healthy tissue is minimally affected. This therapeutic strategy relies on radiopharmaceuticals made of medically relevant radionuclides chelated by ligands, and conjugated to targeting vectors, which promote the drug accumulation in tumor sites. This review discusses the state-of-the-art in the development of radiopharmaceuticals for targeted alpha therapy, breaking down their key structural components, such as radioisotope, targeting vector, and delivery formulation, and analyzing their pros and cons. Moreover, we discuss current drawbacks that are holding back targeted alpha therapy in the clinic, and identify ongoing strategies in field to overcome those issues, including radioisotope encapsulation in nanoformulations to prevent the release of the daughters. Lastly, we critically discuss potential opportunities the field holds, which may contribute to targeted alpha therapy becoming a gold standard treatment in oncology in the future.

62 RADIOLOGY AND NUCLEAR MEDICINE↗
DOE OSTI2017

Formation and Eruption Process of a Filament in Active Region NOAA 12241

In order to better understand active-region filaments, we present an intensive study on the formation and eruption of a filament in active region NOAA 12241 during the period from 2014 December 18 to 19. Using observations from the Helioseismic and Magnetic Imager (HMI) vector magnetograms, we investigate the helicity injection rate, Lorentz force, and vertical electric current in the entire region associated with the filament. The helicity injection rate before eruption is found to be larger than that after eruption, while the vertical electric current undergoes an increase at first and then a gradual decrease, similar to what the magnetic flux undergoes. Meanwhile, we find that the right part of the filament is formed by magnetic reconnection between two bundles of magnetic field lines while the left part originated from shearing motion. The interaction of the two parts causes the eruption of this filament. The mean horizontal magnetic fields in the vicinity of the magnetic polarity inversion line (PIL) enhance rapidly during the eruption. Another striking phenomenon, where the vertical electric currents close to the magnetic PIL suddenly expand toward two sides during the eruption, is found. We propose that this fascinating feature is associated with the release of energy during the eruption.

79 ASTRONOMY AND ASTROPHYSICS↗
NASA NTRS1982

Japanese MAGSAT Team

CHRONINT and investigator B tapes as well as CHRONFIN data are being analyzed using a graphical display to illustrate X.Y,Z components as well as their residuals from the MGST (4/81) model. In addition to surveys of the vicinity of Japan, an aerial magnetic survey was conducted around Syowa Station in the Antarctic. Relative data collected by polar orbiting satellites are also being studied. Techniques used to separate external and internal fields from the vector data along the orbital paths; analysis of the frequency of the toroidal current in the equatorial ionosphere; investigation of the sudden storm commencement observed by MAGSAT; determination of the structure of field aligned currents associated with substorms; and calculation of the total electric current passing through the plane encircled by the MAGSAT orbit are discussed.

Fukushima, N.↗
NASA NTRS1984

Measurements of the thermal plasma environment of the Space Shuttle

The paper presents some initial results on measurements of the thermal plasma environment obtained by a spherical retarding potential analyzer and a Langmuir probe flown on (STS-3) as part of the NASA Office of Space Science-1 payload in March 1982. One of the major effects observed is a higher degree of turbulence in the ambient plasma compared to what is observed from similar instruments flown on unmanned satellites. In addition we see the temperature of the thermal electrons elevated to values of 4000-5000 K. Associated with elevated electron temperatures are regions of enhanced plasma density resulting from the appearance of high densities of molecular ions. The thermal plasma data also show clear effects of an induced V x B.L potential at the location of the probes which matches that produced by an L vector linking the probes to the engine nozzles; thereby establishing the prime return current location on the Orbiter. The final observations discussed are the pronounced and complex wake effects resulting both from the main structure of the Orbiter and from the complex shapes of appendages attached to the Orbiter.

Raitt, W. J.↗
NASA NTRS1986

4800 B/S speech compression techniques for mobile satellite systems

This paper will discuss three 4800 bps digital speech compression techniques currently being investigated for application in the mobile satellite service. These three techniques, vector adaptive predictive coding, vector excitation coding, and the self excited vocoder, are the most promising among a number of techniques being developed to possibly provide near-toll-quality speech compression while still keeping the bit-rate low enough for a power and bandwidth limited satellite service.

Townes, S. A.↗
NASA NTRS1994

Numerical simulation of the flow about the F-18 HARV at high angle of attack

As part of NASA's High Alpha Technology Program, research has been aimed at developing and extending numerical methods to accurately predict the high Reynolds number flow about the NASA F-18 High Alpha Research Vehicle (HARV) at large angles of attack. The HARV aircraft is equipped with a bidirectional thrust vectoring unit which enables stable, controlled flight through 70 deg angle of attack. Currently, high-fidelity numerical solutions for the flow about the HARV have been obtained at alpha = 30 deg, and validated against flight-test data. It is planned to simulate the flow about the HARV through alpha = 60 deg, and obtain solutions of the same quality as those at the lower angles of attack. This report presents the status of work aimed at extending the HARV computations to the extreme angle of attack range.

Murman, Scott M.↗
NASA NTRS1996

Computational Issues Associated with Temporally Deforming Geometries Such as Thrust Vectoring Nozzles

During the past decade, computational simulation of fluid flow around complex configurations has progressed significantly and many notable successes have been reported, however, unsteady time-dependent solutions are not easily obtainable. The present effort involves unsteady time dependent simulation of temporally deforming geometries. Grid generation for a complex configuration can be a time consuming process and temporally varying geometries necessitate the regeneration of such grids for every time step. Traditional grid generation techniques have been tried and demonstrated to be inadequate to such simulations. Non-Uniform Rational B-splines (NURBS) based techniques provide a compact and accurate representation of the geometry. This definition can be coupled with a distribution mesh for a user defined spacing. The present method greatly reduces cpu requirements for time dependent remeshing, facilitating the simulation of more complex unsteady problems. A thrust vectoring nozzle has been chosen to demonstrate the capability as it is of current interest in the aerospace industry for better maneuverability of fighter aircraft in close combat and in post stall regimes. This current effort is the first step towards multidisciplinary design optimization which involves coupling the aerodynamic heat transfer and structural analysis techniques. Applications include simulation of temporally deforming bodies and aeroelastic problems.

Boyalakuntla, Kishore↗
NASA NTRS1999

Electric Field Double Probe Measurements on Satellites with Very Low Perigees

Measurements of DC and AC electric Fields at low altitudes (less than 150 km) in the Earth's ionosphere address a wide array of important scientific questions including Joule Heating, the closure of field aligned currents, and the deviation of E x B electron velocities from ion velocity vectors influenced by collisions. Double probes represent a well-proven technique for gathering high quality DC and AC electric field measurements for which the design of the boom system is of critical importance for the success of the experiment. In general, ionospheric DC electric field instruments that achieve accuracies of 0.1 mV/m or better, place sensors at large distances from the spacecraft body in order to extend well beyond the spacecraft wake and sheath and to achieve the large signal-to-noise ratios for DC and long wavelength measurements. Additional sets of sensors inboard of the primary, outermost sensors provide useful additional information, both for diagnostics of the plasma contact potentials, which particularly enhance the DC electric field measurements on non-spinning spacecraft, and for wavelength and phase velocity measurements that use the spaced receiver or "Interferometer" technique. Accurate attitude knowledge enables V x B contributions to be subtracted from the measured potentials, and permits the measured components to be rotated into meaningful geophysical reference frames. This presentation discusses the expected performance of electric field double probe experiments and their boom mechanisms on both spinning and non-spinning satellite platforms with very low perigees. Careful selection of probe surface materials, such as titanium nitride, for the low perigee environment, as well as thermal considerations are also discussed.

Pfaff, R. F., Jr.↗
NASA NTRS2018

Performance and Evaluation of the Global Modeling and Assimilation Office Observing System Simulation Experiment

The National Aeronautics and Space Administration Global Modeling and Assimilation Office (NASA/GMAO) has spent more than a decade developing and implementing a global Observing System Simulation Experiment framework for use in evaluting both new observation types as well as the behavior of data assimilation systems. The NASA/GMAO OSSE has constantly evolved to relect changes in the Gridpoint Statistical Interpolation data assimiation system, the Global Earth Observing System model, version 5 (GEOS-5), and the real world observational network. Software and observational datasets for the GMAO OSSE are publicly available, along with a technical report. Substantial modifications have recently been made to the NASA/GMAO OSSE framework, including the character of synthetic observation errors, new instrument types, and more sophisticated atmospheric wind vectors. These improvements will be described, along with the overall performance of the current OSSE. Lessons learned from investigations into correlated errors and model error will be discussed.

OSS↗
DOE OSTI2016

Model Predictive Control of A Matrix-Converter Based Solid State Transformer for Utility Grid Interaction

The matrix converter solid state transformer (MC-SST), formed from the back-to-back connection of two three-to-single-phase matrix converters, is studied for use in the interconnection of two ac grids. The matrix converter topology provides a light weight and low volume single-stage bidirectional ac-ac power conversion without the need for a dc link. Thus, the lifetime limitations of dc-bus storage capacitors are avoided. However, space vector modulation of this type of MC-SST requires to compute vectors for each of the two MCs, which must be carefully coordinated to avoid commutation failure. An additional controller is also required to control power exchange between the two ac grids. In this paper, model predictive control (MPC) is proposed for an MC-SST connecting two different ac power grids. The proposed MPC predicts the circuit variables based on the discrete model of MC-SST system and the cost function is formulated so that the optimal switch vector for the next sample period is selected, thereby generating the required grid currents for the SST. Simulation and experimental studies are carried out to demonstrate the effectiveness and simplicity of the proposed MPC for such MC-SST-based grid interfacing systems.

Xue, Yaosuo↗