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At least 559 records · Page 31

First Leptophobic Dark Matter Search from the Coherent–CAPTAIN-Mills Liquid Argon Detector

We report the first results of a search for leptophobic dark matter (DM) from the Coherent–CAPTAIN-Mills (CCM) liquid argon (LAr) detector. An engineering run with 120 photomultiplier tubes (PMTs) and 17.9 × 10 20 protons on target (POT) was performed in fall 2019 to study the characteristics of the CCM detector. The operation of this 10-ton detector was strictly light based with a threshold of 50 keV and used coherent elastic scattering off argon nuclei to detect DM. Despite only 1.5 months of accumulated luminosity, contaminated LAr, and nonoptimized shielding, CCM’s first engineering run has already achieved sensitivity to previously unexplored parameter space of light dark matter models with a baryonic vector portal. With an expected background of 115 005 events, we observe 115 005 + 16.5 events which is compatible with background expectations. For a benchmark mediator-to-DM mass ratio of m V B =m χ = 2.1, DM masses within the range 9 MeV ≲ m χ ≲ 50 MeV are excluded at 90% C. L. in the leptophobic model after applying the Feldman-Cousins test statistic. CCM’s upgraded run with 200 PMTs, filtered LAr, improved shielding, and 10 times more POT will be able to exclude the remaining thermal relic density parameter space of this model, as well as probe new parameter space of other leptophobic DM models.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Search for top-philic heavy resonances in pp collisions at $\sqrt{s}=13$ $\text {TeV}$ with the ATLAS detector

A search for the associated production of a heavy resonance with a top-quark or a top-antitop-quark pair, and decaying into a $\overline{tt}$ pair is presented. The search uses the data recorded by the ATLAS detector in pp collisions at $\sqrt{s}$ = 13 TeV at the Large Hadron Collider during the years 2015–2018, corresponding to an integrated luminosity of 139 fb -1 . Events containing exactly one electron or muon are selected. The two hadronically decaying top quarks from the resonance decay are reconstructed using jets clustered with a large radius parameter of R = 1. The invariant mass spectrum of the two top quark candidates is used to search for a resonance signal in the range of 1.0 TeV to 3.2 TeV. The presence of a signal is examined using an approach with minimal model dependence followed by a model-dependent interpretation. No significant excess is observed over the background expectation. Upper limits on the production cross section times branching ratio at 95% confidence level are provided for a heavy Z' boson based on a simplified model, for Z' mass between 1.0 TeV and 3.0 TeV. The observed (expected) limits range from 21 (14) fb to 119 (86) fb depending on the choice of model parameters

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Black hole induced false vacuum decay: the role of greybody factors

We study false vacuum decay catalyzed by black holes. We consider a toy two-dimensional model of a scalar field with an unstable potential in the background of a dilaton black hole. A realistic black hole in four dimensions possesses the potential barrier for linear field perturbations. We model this barrier — the greybody factor — for spherically-symmetric perturbations in the toy model by adding a coupling between the scalar field and dilaton. We compute analytically the decay rate for the black hole in thermal equilibrium (Hartle-Hawking state) and for the radiating black hole in empty space (Unruh state). Our results show that, contrary to the Hartle-Hawking vacuum, the decay probability of the Unruh vacuum remains exponentially suppressed at all black hole temperatures. We argue that this result holds also in four dimensions.

2D Gravity↗

The Effect of Surface Heating Heterogeneity on Boundary Layer Height and Its Dependence on Background Wind Speed

The planetary boundary layer height (PBLH) is a fundamental variable of the planetary boundary layer (PBL). The effect of surface heterogeneity is challenging in the PBL parameterization for numerical weather and climate models. Here we use large eddy simulation data to investigate the impact of surface heating heterogeneity on the PBLH spatial variations and mean values over a domain of typical mesoscale model grid size. It is found that this impact depends on background wind condition. Variance decomposition and Fourier spectra both reveal that for the fully developed sheared convective PBL, surface heterogeneity contributes little to the spatial variation of PBLH, except for the case with heterogeneity scale of 14.4 km. This suggests that surface heterogeneity with length scales less than ~10 km, which is typical for mesoscale modeling, does not induce significant subgrid spatial variation of PBLH. The domain-averaged PBLH is found to generally increase as surface heterogeneity scale decreases, until reaching the scale on the order of PBLH. The findings can be used to inform the parameterization development of PBL processes over heterogeneous surface.

54 ENVIRONMENTAL SCIENCES↗

Prognostic analysis of high-flow nasal cannula therapy and non-invasive ventilation in mild to moderate hypoxemia patients and construction of a machine learning model for 48-h intubation prediction—a retrospective analysis of the MIMIC database

Background This study aims to investigate the clinical outcome between high-flow nasal cannula (HFNC) and non-invasive ventilation (NIV) therapy in mild to moderate hypoxemic patients on the first ICU day and to develop a predictive model of 48-h intubation. Methods The study included adult patients from the MIMIC III and IV databases who first initiated HFNC or NIV therapy due to mild to moderate hypoxemia (100 < PaO2/FiO2 ≤ 300). The 48-h and 30-day intubation rates were compared using cross-sectional and survival analysis. Nine machine learning and six ensemble algorithms were deployed to construct the 48-h intubation predictive models, of which the optimal model was determined by its prediction accuracy. The top 10 risk and protective factors were identified using the Shapley interpretation algorithm. Result A total of 123,042 patients were screened, of which, 673 were from the MIMIC IV database for ventilation therapy comparison (HFNC n = 363, NIV n = 310) and 48-h intubation predictive model construction (training dataset n = 471, internal validation set n = 202) and 408 were from the MIMIC III database for external validation. The NIV group had a lower intubation rate (23.1% vs. 16.1%, p = 0.001), ICU 28-day mortality (18.5% vs. 11.6%, p = 0.014), and in-hospital mortality (19.6% vs. 11.9%, p = 0.007) compared to the HFNC group. Survival analysis showed that the total and 48-h intubation rates were not significantly different. The ensemble AdaBoost decision tree model (internal and external validation set AUROC 0.878, 0.726) had the best predictive accuracy performance. The model Shapley algorithm showed Sequential Organ Failure Assessment (SOFA), acute physiology scores (APSIII), the minimum and maximum lactate value as risk factors for early failure and age, the maximum PaCO 2 and PH value, Glasgow Coma Scale (GCS), the minimum PaO 2 /FiO 2 ratio, and PaO 2 value as protective factors. Conclusion NIV was associated with lower intubation rate and ICU 28-day and in-hospital mortality. Further survival analysis reinforced that the effect of NIV on the intubation rate might partly be attributed to the other impact factors. The ensemble AdaBoost decision tree model may assist clinicians in making clinical decisions, and early organ function support to improve patients’ SOFA, APSIII, GCS, PaCO 2 , PaO 2 , PH, PaO 2 /FiO 2 ratio, and lactate values can reduce the early failure rate and improve patient prognosis.

Fu, Wei↗

Comparison of Conventional and Constrained Variational Methods for Computing Large-Scale Budgets and Forcing Fields

Analyses of atmospheric heat and moisture budgets serve as an effective tool to study convective characteristics over a region and to provide large-scale forcing fields for various modeling applications. This paper examines two popular methods for computing large-scale atmospheric budgets: the conventional budget method (CBM) using objectively gridded analyses based primarily on radiosonde data and the constrained variational analysis (CVA) approach which supplements vertical profiles of atmospheric fields with measurements at the top of the atmosphere and at the surface to conserve mass, water, energy, and momentum. Successful budget computations are dependent on accurate sampling and analyses of the thermodynamic state of the atmosphere and the divergence field associated with convection and the large-scale circulation that influences it. Utilizing analyses generated from data taken during Dynamics of the Madden-Julian Oscillation (DYNAMO) field campaign conducted over the central Indian Ocean from October to December 2011, we evaluate the merits of these budget approaches and examine their limitations. While many of the shortcomings of the CBM, in particular effects of sampling errors in sounding data, are effectively minimized with CVA, accurate large-scale diagnostics in CVA are dependent on reliable background fields and rainfall constraints. Finally, for the DYNAMO analyses examined, the operational model fields used as the CVA background state provided wind fields that accurately resolved the vertical structure of convection in the vicinity of Gan Island. However, biases in the model thermodynamic fields were somewhat amplified in CVA resulting in a convective environment much weaker than observed.

54 ENVIRONMENTAL SCIENCES↗

Interpretable boosted-decision-tree analysis for the Majorana Demonstrator

The Majorana Demonstrator is a leading experiment searching for neutrinoless double-beta decay with high purity germanium detectors (HPGe). Machine learning provides a new way to maximize the amount of information provided by these detectors, but the data-driven nature makes it less interpretable compared to traditional analysis. An interpretability study reveals the machine's decision-making logic, allowing us to learn from the machine to feedback to the traditional analysis. In this work, we have presented the first machine learning analysis of the data from the Majorana Demonstrator; this is also the first interpretable machine learning analysis of any germanium detector experiment. Two gradient boosted decision tree models are trained to learn from the data, and a game-theory-based model interpretability study is conducted to understand the origin of the classification power. By learning from data, this analysis recognizes the correlations among reconstruction parameters to further enhance the background rejection performance. By learning from the machine, this analysis reveals the importance of new background categories to reciprocally benefit the standard Majorana analysis. This model is highly compatible with next-generation germanium detector experiments like LEGEND since it can be simultaneously trained on a large number of detectors.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Classification of compact objects and model comparison using EOS knowledge

Nuclear theory and experiments, alongside astrophysical observations, constrain the equation of state (EOS) of supranuclear-dense matter. Conversely, knowledge of the EOS allows an improved interpretation of nuclear or astrophysical data. In this article, we use several established constraints on the EOS and the new NICER measurement of PSR J0437-4715 to comment on the nature of the primary companion in GW230529 and the companion of PSR J0514-4002E. We find that, with a probability of ≳84% and ≳68%, respectively, both objects are black holes. These likelihoods increase to above 95% when one uses GW170817’s remnant as an upper limit on the TOV mass. We also demonstrate that the current knowledge of the EOS substantially disfavors high masses and radii for PSR J⁢0030+0451, inferred recently when combining NICER with XMM-Newton background data and using particular hot-spot models. Lastly, we also use our obtained EOS knowledge to comment on measurements of the nuclear symmetry energy, finding that the large value predicted by the PREX-II measurement displays some mild tension with other constraints on the EOS.

79 ASTRONOMY AND ASTROPHYSICS↗

Cosmic Axion Background detection using resonant cavity arrays

The axion is a well-motivated and generic extension of the Standard Model. If produced in the early universe, axions may still be relativistic today, forming a Cosmic Axion Background (CaB) potentially detectable in direct detection experiments. Although CaB is expected to be broadband, which makes it challenging to be detected, a high-quality-factor microwave cavity acts as a narrowband filter with response peaked at its resonant frequency. We propose a new strategy using multi-cavity arrays to distinguish signal from background noise by exploiting spatial correlations of the axion-induced electric field which are set by the cavity quality factor. We compute the two-point correlation function for electric fields in spatially separated cavities sourced by an isotropic CaB. Analyzing various cavity geometries, we find that stacked, wide-base cavity arrays offer coherent enhancement of the axion signal. We apply our formalism to prospective upgrades of the ADMX experiment, including configurations with four and eighteen coupled cavities. Although these arrays do not achieve a coherent enhancement, optimizing the geometry could potentially yield an $\mathcal{O}(1)$ improvement in the sensitivity to the CaB.

Axions and ALPs↗

Constraints on cosmology and baryonic feedback with joint analysis of Dark Energy Survey Year 3 lensing data and ACT DR6 thermal Sunyaev-Zel'dovich effect observations

We present a joint analysis of weak gravitational lensing (shear) data obtained from the first three years of observations by the Dark Energy Survey and thermal Sunyaev-Zel'dovich (tSZ) effect measurements from a combination of Atacama Cosmology Telescope (ACT) and Planck data. A combined analysis of shear (which traces the projected mass) with the tSZ effect (which traces the projected gas pressure) can jointly probe both the distribution of matter and the thermodynamic state of the gas, accounting for the correlated effects of baryonic feedback on both observables. We detect the shear$~\times~$tSZ cross-correlation at a 21$\sigma$ significance, the highest to date, after minimizing the bias from cosmic infrared background leakage in the tSZ map. By jointly modeling the small-scale shear auto-correlation and the shear$~\times~$tSZ cross-correlation, we obtain $S_8 = 0.811^{+0.015}_{-0.012}$ and $\Omega_{\rm m} = 0.263^{+0.023}_{-0.030}$, results consistent with primary CMB analyses from Planck and P-ACT. We find evidence for reduced thermal gas pressure in dark matter halos with masses $M < 10^{14} \, M_{\odot}/h$, supporting predictions of enhanced feedback from active galactic nuclei on gas thermodynamics. A comparison of the inferred matter power suppression reveals a $2-4\sigma$ tension with hydrodynamical simulations that implement mild baryonic feedback, as our constraints prefer a stronger suppression. Finally, we investigate biases from cosmic infrared background leakage in the tSZ-shear cross-correlation measurements, employing mitigation techniques to ensure a robust inference. Our code is publicly available on GitHub.

Pandey, S. [Johns Hopkins U.; Columbia U.] (ORCID:↗

Search for neutral long-lived particles that decay into displaced jets in the ATLAS calorimeter in association with leptons or jets using pp collisions at $\sqrt{\textrm{s}}$ = 13 TeV

A search for neutral long-lived particles (LLPs) decaying in the ATLAS hadronic calorimeter using 140 fb -1 of proton-proton collisions at $\sqrt{s}$ = 13 TeV delivered by the LHC is presented. The analysis is composed of three channels. The first targets pair-produced LLPs, where at least one LLP is produced with sufficiently low boost that its decay products can be resolved as separate jets. The second and third channels target LLPs respectively produced in association with a W or Z boson that decays leptonically. In each channel, different search regions target different kinematic regimes, to cover a broad range of LLP mass hypotheses and models. No excesses of events relative to the background predictions are observed. Higgs boson branching fractions to pairs of hadronically decaying neutral LLPs larger than 1% are excluded at 95% confidence level for proper decay lengths in the range of 30 cm to 4.5 m depending on the LLP mass, a factor of three improvement on previous searches in the hadronic calorimeter. The production of long-lived dark photons in association with a Z boson with cross-sections above 0.1 pb is excluded for dark photon mean proper decay lengths in the range of 20 cm to 50 m, improving previous ATLAS results by an order of magnitude. Finally, long-lived photo-phobic axion-like particle models are probed for the first time by ATLAS, with production cross-sections above 0.1 pb excluded in the 0.1 mm to 10 m range.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

End-to-End Physics Event Classification with CMS Open Data: Applying Image-Based Deep Learning to Detector Data for the Direct Classification of Collision Events at the LHC

This paper describes the construction of novel end-to-end image-based classifiers that directly leverage low-level simulated detector data to discriminate signal and background processes in pp collision events at the Large Hadron Collider at CERN. To better understand what end-to-end classifiers are capable of learning from the data and to address a number of associated challenges, we distinguish the decay of the standard model Higgs boson into two photons from its leading background sources using high-fidelity simulated CMS Open Data. We demonstrate the ability of end-to-end classifiers to learn from the angular distribution of the photons recorded as electromagnetic showers, their intrinsic shapes, and the energy of their constituent hits, even when the underlying particles are not fully resolved, delivering a clear advantage in such cases over purely kinematics-based classifiers.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Investigation of the background in coherent J/ψ production at the EIC

Understanding various fundamental properties of nucleons and nuclei is among the most important scientific goals at the upcoming Electron-Ion Collider (EIC). With the unprecedented opportunity provided by the next-generation machine, the EIC might provide definitive answers to many standing puzzles and open questions in modern nuclear physics. We investigate one of the golden measurements proposed at the EIC, which is to obtain the spatial gluon density distribution within a lead (Pb) nucleus. The proposed experimental process is the exclusive J/ψ vector-meson production off the Pb nucleus: e + Pb → e' + J/ψ + Pb'. The Fourier transformation of the momentum transfer |t| distribution of the coherent diffraction is the transverse gluon spatial distribution. In order to measure it, the experiment has to overcome an overwhelmingly large background arising from the incoherent diffractive production, where the nucleus Pb' mostly breaks up into fragments of particles in the far-forward direction close to the hadron-going beam rapidity. We systematically study the rejection of incoherent J/ψ production by vetoing products from these nuclear breakups—protons, neutrons, and photons—which is based on the BeAGLE event generator and the most up-to-date EIC Far-forward Interaction Region design. The achieved vetoing efficiency, the ratio between the numbers of vetoed events and total incoherent events, ranges from about 80% to 99% depending on |t|. Assuming a 5% smearing applied to the reconstructed |t| resolution in the Sar t re model, this vetoing efficiency can suppress the incoherent background to at least the first minimum of the coherent |t| distribution. Experimental and accelerator machine challenges as well as potential improvements are discussed herein.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗

Effect of Anoxic Iron Corrosion on WIPP Brine Geochemistry FY23 Final Report (U)

A 280-day study was completed to evaluate the effect of zero-valent iron (Fe 0 ) on the Waste Isolation Pilot Plant (WIPP) brine geochemistry under anticipated reducing conditions. Hydrogen (H 2 ) gas is expected to be present in the repository after closure due to the anoxic corrosion of a vast quantity of iron contained in the waste forms disposed at WIPP; therefore, a background argon atmosphere containing H 2 was chosen for this study. WIPP groundwater brine pH and E h will impact the mobility and fate of plutonium within the repository. Modeling and laboratory results for Castile WIPP brine indicate that equilibrium fa values relative to the standard hydrogen electrode (SHE) are 40 mV more reducing (i.e., more negative) than those for Salado WIPP brine (-480 mV vs. -440 mV, respectively) because of the higher pH of the Castile brine (pH 9 .3 for Castile vs. pH 8.8 for Salado). The E h and pH data were corrected for the effects of high ionic strength. The experimental results for both brines are consistent with thermodynamic predictions using OLI Systems' Mixed Solvent Electrolyte chemical equilibrium model. The measured and corrected pH and E h data from this study are provided in Table ES-I and Table ES-2, respectively. The experimental study, with four test conditions in triplicate, was performed in a dual glovebox with a nominally 3 vol.% H 2 in argon atmosphere (target H 2 range: 3 ± I vol.%). Simulants containing MgO only ( experimental control) and MgO+Fe 0 (WIPP base case) were prepared for both the Salado and Castile brines. MgO was included in all simulants to account for the use of bulk magnesium oxide in the WIPP repository. Fe 0 was included in some simulants to incorporate the effects of the anoxic corrosion of iron and in-situ hydrogen generation in the study. The brine compositions were developed by Sandia National Laboratory (SNL; Xiong, 2008) and have been used in previous WIPP evaluations. The test method (agitation, etc.) is partially based on ASTM D3987-12. Twelve rounds of periodic measurements of pH and E h were performed over the course of the study. Chemical analysis results for liquids and solids (ICP-MS, ICP-ES, IC Anion, TIC, SEM-EDX) are consistent with the pH, E h , and thermodynamic modeling results. This study included the following conditions that deviate from anticipated post-closure conditions following brine intrusion, but were selected to facilitate bench-scale testing to validate modeling of pH and E h for the post-closure WIP P repository: an anoxic glove box atmosphere containing ≤ 4 vol. % H 2 vs. substantially higher H 2 gas concentrations assumed in the WIPP Performance Assessment (PA); a significantly higher liquid-to-solid test ratio compared to the much lower phase ratio anticipated in the WIP P repository; agitation of the simulant bottles to maximize mass transfer; and finally the use of Fe 0 reagents having a much greater surface area than expected in the WIP P repository. Non-representative conditions were chosen for various reasons such as: to provide bounding conservative results, to provide a margin of safety for testing, or to facilitate simulant sub-sampling and analysis. In a parallel effort, aqueous electrolyte thermodynamic models were developed for the synthetic Salado and Castile brines to inform the experimental design, facilitate laboratory data interpretation, and allow extension of evaluations beyond the parameters tested. Thermodynamic modeling simulations including the MgO and Fe 0 additives that are directly relevant to the experimental measurements (e.g., pH calibration curve, ORP corrections) are included in this report. The measured fa of the simulants was close to the OLI model predictions for both brines and was largely controlled by the background H 2 partial pressure in the vapor phase as well as H 2 generated in situ in the aqueous phase by the Fe 0 corrosion. The H 2 gas-phase concentration tested and thermodynamically evaluated was much lower than is assumed in the WIPP PA; however, H 2 (g) concentrations significantly below this level are still predicted to result in very reducing conditions. In conclusion: • The experimental results are consistent with thermodynamic model predictions for fa, pH, and the effects of high ionic strength. • Evidence to date suggests that the H2 concentration in the glovebox atmosphere ultimately determined the final E h values of the simulants and resulted in highly reducing conditions. As a result, little difference was observed between the control simulants containing only MgO and the WIPP base-case simulants that contained MgO and Fe 0 . • This test methodology is recommended for future studies evaluating WIPP repository conditions. The methodology includes: (1) background H 2 in argon with agitation ( or could alternatively include in-situ-generated H 2 in sealed bottles); (2) carefully measured and corrected ORP data ( with much effort focused on allowing the probes to fully stabilize); and (3) ionic-strength-corrected pH data. Other best practices, such as simulant sparging/handling, ORP probe replacement, etc., should also be considered. • The coupling of experimental studies and thermodynamic modeling is also highly recommended because these methods inform and direct one another leading to greater confidence in and understanding of the results.

12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗

Jet quenching in the glasma phase: Medium-induced radiation

Inspired by the recent considerations of parton momentum broadening in the glasma phase, we study the medium-induced soft gluon radiation of jet partons at early times in heavy-ion collisions. The glasma state is assumed to be comprised of independent color domains with homogenous longitudinal fields that vary event by event, and we further complete this model with an event-averaging procedure accounting for the finite correlation length. Using this description, we evaluate the rate of medium-induced radiation from an energetic parton at midrapidity in the glasma phase. We mainly focus on SU(2) color fields for simplicity, also referring to the U(1) case and comparing with the Baier, Dokshitzer, Mueller, Peigné, Schiff, and Zakharov rate to gain further insight. Our results show that there is an intricate interplay of the synchrotron-like radiation in a single color domain with the destructive interference between different color domains, after the medium averaging is performed. Thus, we find that the emission rate is sensitive to the matter structure, decreasing for a glasma state populated by smaller color domains—i.e., for a glasma with a larger characteristic saturation scale. Our approach can be applied to more realistic backgrounds, and it sets the stage for the modeling of jet evolution in the early stages of heavy-ion collisions.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗

Search for direct pair production of sleptons and charginos decaying to two leptons and neutralinos with mass splittings near the $W$-boson mass in $\sqrt{s}$ = 13 TeV pp collisions with the ATLAS detector

A search for the electroweak production of pairs of charged sleptons or charginos decaying into two-lepton final states with missing transverse momentum is presented. Two simplified models of R-parity-conserving supersymmetry are considered: direct pair-production of sleptons ($\sim\atop{\ell}$$\sim\atop{\ell}$), with each decaying into a charged lepton and a $\sim\atop{\chi}$ $^{0}_{1}$ neutralino, and direct pair-production of the lightest charginos ($\sim\atop{\chi}$ $^{±}_{1}$ $\sim\atop{\chi}$ $^{∓}_{1}$), with each decaying into a W-boson and a $\sim\atop{\chi}$ $^{0}_{1}$. The lightest neutralino ($\sim\atop{\chi}$ $^{0}_{1}$) is assumed to be the lightest supersymmetric particle (LSP). The analyses target the experimentally challenging mass regions where $m$($\sim\atop{\ell}$) - $m$($\sim\atop{\chi}$ $^{0}_{1}$) and ($m$$\sim\atop{\chi}$ $^{±}_{1}$) – )$m$$\sim\atop{\chi}$ $^{0}_{1}$) are close to the W-boson mass (‘moderately compressed’ regions). The search uses 139 fb –1 of $\sqrt{s}$ = 13 TeV proton-proton collisions recorded by the ATLAS detector at the Large Hadron Collider. No significant excesses over the expected background are observed. Exclusion limits on the simplified models under study are reported in the ($\sim\atop{\ell}$, $\sim\atop{\chi}$ $^{0}_{1}$) and ($\sim\atop{\chi}$ $^{±}_{1}$, $\sim\atop{\chi}$ $^{0}_{1}$) mass planes at 95% confidence level (CL). Sleptons with masses up to 150 GeV are excluded at 95% CL for the case of a mass-splitting between sleptons and the LSP of 50 GeV. Chargino masses up to 140 GeV are excluded at 95% CL for the case of a mass-splitting between the chargino and the LSP down to about 100 GeV.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

The impact of varying inhomogeneous reionization histories on metrics of Ly α opacity

The epoch of hydrogen reionization is complete by z = 5⁠, but its progression at higher redshifts is uncertain. Measurements of Ly α forest opacity show large scatter at z < 6⁠, suggestive of spatial fluctuations in neutral fraction, temperature, or ionizing background, either individually or in combination. However, there are degeneracies in the impact of such fluctuations, necessitating careful modelling. We develop a framework for modelling the reionization history and associated temperature fluctuations, with the intention of incorporating ionizing background fluctuations at a later time. We generate several reionization histories using seminumerical code AMBER, and implement them in the Nyx cosmological hydrodynamics code to examine the impact on the evolution of gas within the simulation and the associated metrics of the Ly α forest opacity. We find that the pressure smoothing scale within the intergalactic medium is strongly correlated with the adiabatic index of the temperature–density relation. We find that while models with 20 000 K photoheating at reionization are better able to reproduce the shape of the observed z = 5 1D flux power spectrum than colder ones, they fail to match the highest wavenumbers. The simulated autocorrelation function and optical depth distributions are systematically low and narrow, respectively, compared to the observed values, but are in better agreement when the reionization history is longer in duration, more symmetric in its distribution of reionization redshifts, or if there are remaining neutral regions at z < 6.

79 ASTRONOMY AND ASTROPHYSICS↗

Hypergraph Models of Biological Networks to Identify Genes Critical to Pathogenic Viral Response

Motivation: Representing biological networks as graphs is a powerful approach to reveal underlying patterns, signatures, and critical components from high-throughput biomolecular data. However, graphs do not natively capture the multi-way relationships present among genes and proteins in biological systems such as protein complexes, metabolic reactions, and signal transduction pathways. Hypergraphs are generalizations of graphs that naturally model multi-way interactions in data, and we therefore seek to understand how they can more faithfully identify, and potentially predict, complex relationships in genomic expression data sets. Results: We compiled a novel data set of transcriptional host response to pathogenic viral infections and formulated relationships between genes as a hypergraph where hyperedges are differentially expressed genes and vertices represent conditions. We find that hypergraph betweenness centrality is a superior method for identification of genes important to viral response when compared with graph centrality. Our results demonstrate the utility of using hypergraphs to represent complex biological systems, and highlight potentially interesting biological results about host response to highly pathogenic viruses.

systems biology, hypergraph, viral infection, biol↗