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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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All sourcesNASA NTRSDOE OSTI
DOE OSTI2024

Differential patterns of reproductive and lifestyle risk factors for breast cancer according to birth cohorts among women in China, Japan and Korea

Background: The birth cohort effect has been suggested to influence the rate of breast cancer incidence and the trends of associated reproductive and lifestyle factors. We conducted a cohort study to determine whether a differential pattern of associations exists between certain factors and breast cancer risk based on birth cohorts. Methods: This was a cohort study using pooled data from 12 cohort studies. We analysed associations between reproductive (menarche age, menopause age, parity and age at first delivery) and lifestyle (smoking and alcohol consumption) factors and breast cancer risk. We obtained hazard ratios (HRs) with 95% confidence intervals (CIs) using the Cox proportional hazard regression analysis on the 1920s, 1930s, 1940s and 1950s birth cohorts. Results: Parity was found to lower the risk of breast cancer in the older but not in the younger birth cohort, whereas lifestyle factors showed associations with breast cancer risk only among the participants born in the 1950s. In the younger birth cohort group, the effect size was lower for parous women compared to the other cohort groups (HR [95% CI] 0.86 [0.66–1.13] compared to 0.60 [0.49–0.73], 0.46 [0.38–0.56] and 0.62 [0.51–0.77]). Meanwhile, a higher effect size was found for smoking (1.45 [1.14–1.84] compared to 1.25 [0.99–1.58], 1.06 [0.85–1.32] and 0.86 [0.69–1.08]) and alcohol consumption (1.22 [1.01–1.48] compared to 1.10 [0.90–1.33], 1.15 [0.96–1.38], and 1.07 [0.91–1.26]). Conclusion: We observed different associations of parity, smoking and alcohol consumption with breast cancer risk across various birth cohorts.

60 APPLIED LIFE SCIENCES↗
DOE OSTI2024

Urbanization and malaria have a contextual relationship in endemic areas: A temporal and spatial study in Ghana

In West Africa, malaria is one of the leading causes of disease-induced deaths. Existing studies indicate that as urbanization increases, there is corresponding decrease in malaria prevalence. However, in malaria-endemic areas, the prevalence in some rural areas is sometimes lower than in some peri-urban and urban areas. Therefore, the relationship between the degree of urbanization, the impact of living in urban areas, and the prevalence of malaria remains unclear. This study explores this association in Ghana, using epidemiological data at the district level (2015–2018) and data on health, hygiene, and education. We applied a multilevel model and time series decomposition to understand the epidemiological pattern of malaria in Ghana. Then we classified the districts of Ghana into rural, peri-urban, and urban areas using administratively defined urbanization, total built areas, and built intensity. We converted the prevalence time series into cross-sectional data for each district by extracting features from the data. To predict the determinant most impacting according to the degree of urbanization, we used a cluster-specific random forest. We find that prevalence is impacted by seasonality, but the trend of the seasonal signature is not noticeable in urban and peri-urban areas. While urban districts have a slightly lower prevalence, there are still pockets with higher rates within these regions. These areas of high prevalence are linked to proximity to water bodies and waterways, but the rise in these same variables is not associated with the increase of prevalence in peri-urban areas. The increase in nightlight reflectance in rural areas is associated with an increased prevalence. We conclude that urbanization is not the main factor driving the decline in malaria. However, the data indicate that understanding and managing malaria prevalence in urbanization will necessitate a focus on these contextual factors. Finally, we design an interactive tool, ’malDecision’ that allows data-supported decision-making.

60 APPLIED LIFE SCIENCES↗
DOE OSTI2025

Hydrology controls thermokarst and alters carbon cycling and methane emissions in peatlands near the southern limit of permafrost: Model Inputs and Outputs

This dataset contains model inputs and simulation outputs associated with the study “Hydrology controls thermokarst and alters carbon cycling and methane emissions in peatlands near the southern limit of permafrost.” The ecosys model was extended to represent thermokarst processes in laterally coupled two-dimensional transects and applied to the Scotty Creek basin (Northwest Territories, Canada). The ecosys model and documentation is available for download at https://github.com/jinyun1tang/ECOSYS. The dataset contains the inputs used to run the model for this study (meteorological forcing data (1950–2018) and site-specific soil and vegetation parameters) and model outputs used to generate Figure 3 and Figure 4 in the paper (simulated ground thermal and hydrologic states, vegetation dynamics, and carbon fluxes).

54 ENVIRONMENTAL SCIENCES↗
DOE OSTI2026

Historic climate, cosmogenic 10Be, denudation-rate, and geospatial datasets from the Pikes Peak region, Colorado, USA

This data package contains geographic information system (GIS) layers and tabular datasets associated with the study of elevation-dependent denudation rates on Pikes Peak in the Front Range of the Rocky Mountains, Colorado, USA. The package includes GIS layers used to produce the study-area map, including sample locations, sample watershed boundaries, the Pikes Peak batholith, Pleistocene glacier extent, weather station locations, and elevation and hillshade rasters, together with comma-separated value (CSV) tables and matching CSV data dictionaries. These mapped layers provide the geographic framework for interpreting denudation patterns across the Pikes Peak region and for relating sample locations to watershed geometry, bedrock setting, glacial history, and nearby climate stations. The first group of tables reports climate and geospatial context for the study area. These files include station-based temperature and precipitation data used to characterize elevational gradients in mean annual climate and monthly climate seasonality, sample locations, denudation-rate and topographic metrics, fixed frost-cracking model parameters, frost-cracking intensity and precipitation-frequency metrics, and stream-power inversion results. Together, these data provide the basis for evaluating how denudation varies with elevation, climate, and landscape form across sampled catchments on Pikes Peak. The second group of tables reports cosmogenic nuclide and erosion-model results used in the denudation analysis. Included files contain accelerator mass spectrometry (AMS) measurements for in situ-produced cosmogenic beryllium-10 (10Be), including sample identifiers, measured 10Be:9Be ratios, analytical uncertainties, carrier mass, quartz mass, blank corrections, blank-group statistics, and calculated 10Be concentrations and uncertainties. Additional tables summarize stream-power-law inversion results for sampled catchments, including optimized model parameters, predicted erosion rates, residual metrics, channel-pixel counts, and convergence status, as well as regression equations and summary statistics used to evaluate relationships among elevation, climate, frost cracking, precipitation forcing, and denudation rate. The package contains GIS files, comma-separated value files (.csv), Microsoft Excel files (.xlsx), CSV data dictionaries, a file-level metadata table, and a readme text file.

10Be cosmogenic nuclides↗
DOE OSTI2023

The Effect of Prostate-Specific Antigen (PSA) Test on Radiation Risk Estimate for Prostate Cancer Incidence among Atomic-Bomb Survivors

Following our previous report on the radiation doseresponse for prostate cancer incidence rates in the Life Span Study (LSS) cohort of atomic bomb survivors, we reevaluated the radiation-related risk adjusting for differences in baseline cancer incidence rates among three subsets of the LSS cohort defined by the timing of their first participation in biennial health examinations offered to the Adult Health Study (AHS) sub-cohort members and prostate-specificantigen (PSA) testing status for AHS participants: 1. nonAHS participants, 2. AHS participants before receiving PSA test, and 3. AHS participants after receiving PSA test. We found a 2.9-fold increase in the baseline incidence rates among AHS participants after receiving PSA test. After adjusting for the PSA-testing-status effects on the baseline rates the estimated excess relative risk (ERR) per Gy was 0.54 (95% CI: 0.15, 1.05), which was almost identical to the previously reported unadjusted ERR estimate (0.57, 95% CI: 0.21, 1.00). The current results confirmed that, while the PSA testing among AHS participants increased the baseline incidence rates, it did not impact the radiation risk estimate, strengthening the previously reported dose-response relationship for prostate cancer incidence in the LSS. As the use of PSA tests continue in screening and medical settings, analyses of possible effects of PSA testing should be an important aspect of future epidemiological studies of the association between radiation exposure and prostate cancer.

62 RADIOLOGY AND NUCLEAR MEDICINE↗
DOE OSTI2020

Hydropower Geotechnical Foundations: Executive Summary on Current Practice and Innovation Opportunities for Low-Head Applications

The following content provides a companion executive summary of Hydropower Geotechnical Foundations: Current Practice and Innovation Opportunities for Low-Head Applications (DeNeale et al. 2020), a technical report developed by Oak Ridge National Laboratory (ORNL) and Knight Piésold Consulting, with funding from the US Department of Energy (DOE) Water Power Technologies Office (WPTO). This executive summary provides a brief synopsis of the broader information contained in the technical report. This study (and the associated technical report): (1) covers background information on hydropower; (2) describes various characteristics relevant to hydropower foundations for undeveloped US streams; (3) presents the current state of practice in foundation development; (4) provides a representative assessment of conventional hydropower foundation costs and timelines; (5) addresses key challenges facing conventional hydropower foundations; and (6) presents opportunity areas and examples for innovative hydropower foundation technologies while highlighting some advances in non-hydropower industries.

13 HYDRO ENERGY↗
DOE OSTI2024

PyPop: a mature open-source software pipeline for population genomics

Python for Population Genomics (PyPop) is a software package that processes genotype and allele data and performs large-scale population genetic analyses on highly polymorphic multi-locus genotype data. In particular, PyPop tests data conformity to Hardy-Weinberg equilibrium expectations, performs Ewens-Watterson tests for selection, estimates haplotype frequencies, measures linkage disequilibrium, and tests significance. Standardized means of performing these tests is key for contemporary studies of evolutionary biology and population genetics, and these tests are central to genetic studies of disease association as well. Here, we present PyPop 1.0.0, a new major release of the package, which implements new features using the more robust infrastructure of GitHub, and is distributed via the industry-standard Python Package Index. New features include implementation of the asymmetric linkage disequilibrium measures and, of particular interest to the immunogenetics research communities, support for modern nomenclature, including colon-delimited allele names, and improvements to meta-analysis features for aggregating outputs for multiple populations.

59 BASIC BIOLOGICAL SCIENCES↗
DOE OSTI2022

Nitrogen fixation and mucilage production on maize aerial roots is controlled by aerial root development and border cell functions

Exploring natural diversity for biological nitrogen fixation in maize and its progenitors is a promising approach to reducing our dependence on synthetic fertilizer and enhancing the sustainability of our cropping systems. We have shown previously that maize accessions from the Sierra Mixe can support a nitrogen-fixing community in the mucilage produced by their abundant aerial roots and obtain a significant fraction of their nitrogen from the air through these associations. In this study, we demonstrate that mucilage production depends on root cap and border cells sensing water, as observed in underground roots. The diameter of aerial roots correlates with the volume of mucilage produced and the nitrogenase activity supported by each root. Young aerial roots produce more mucilage than older ones, probably due to their root cap’s integrity and their ability to produce border cells. Transcriptome analysis on aerial roots at two different growth stages before and after mucilage production confirmed the expression of genes involved in polysaccharide synthesis and degradation. Genes related to nitrogen uptake and assimilation were up-regulated upon water exposure. Altogether, our findings suggest that in addition to the number of nodes with aerial roots reported previously, the diameter of aerial roots and abundance of border cells, polysaccharide synthesis and degradation, and nitrogen uptake are critical factors to ensure efficient nitrogen fixation in maize aerial roots.

59 BASIC BIOLOGICAL SCIENCES↗
DOE OSTI2026

Prompt Searches for Very-high-energy γ -Ray Counterparts to IceCube Astrophysical Neutrino Alerts

The search for sources of high-energy astrophysical neutrinos can be significantly advanced through a multimessenger approach, which seeks to detect the γ-rays that accompany neutrinos as they are produced at their sources. Multimessenger observations have so far provided the first evidence for a neutrino source, illustrated by the joint detection of the flaring blazar TXS 0506+056 in high-energy (E > 1 GeV) and very-high-energy (VHE; E > 100 GeV) γ-rays in coincidence with the high-energy neutrino IceCube-170922A, identified by IceCube. Imaging atmospheric Cherenkov telescopes (IACTs), namely FACT, H.E.S.S., MAGIC, and VERITAS, continue to conduct extensive neutrino target-of-opportunity follow-up programs. These programs have two components: follow-up observations of single astrophysical neutrino candidate events (such as IceCube-170922A), and observation of known γ-ray sources after the identification of a cluster of neutrino events by IceCube. Here we present a comprehensive analysis of follow-up observations of high-energy neutrino events observed by the four IACTs between 2017 September (after the IceCube-170922A event) and 2021 January. Our study found no associations between γ-ray sources and the observed neutrino events. We provide a detailed overview of each neutrino event and its potential counterparts. Furthermore, a joint analysis of all IACT data is included, yielding combined upper limits on the VHE γ-ray flux.

79 ASTRONOMY AND ASTROPHYSICS↗
DOE OSTI2026

Analysis of genomic signatures associated with Variovorax endosphere colonization

This repository contains the analysis code and supporting datasets associated with the study “Genomic signatures in Variovorax enabling colonization of the Populus endosphere.” Beals DG, Carper DL, Hochanadel LH, Jawdy SS, Klingeman DM, Piatkowski BT, Weston DJ, Doktycz MJ, Pelletier DA. 2026. Genomic signatures in Variovorax enabling colonization of the Populus endosphere. mSystems 11:e01605-25. https://doi.org/10.1128/msystems.01605-25 The scripts are organized sequentially (01–07) and document the workflows used for: Sequence-read alignment and feature counting Orthogroup and KEGG Ortholog annotation Count normalization Statistical analysis and aggregation Generation of manuscript figures and tables Repository contents The uncompressed files are the finalized, formatted datasets used to generate the figures and tables reported in the study, including the supplemental CSV files referenced in the manuscript. The accompanying ZIP archive contains the complete codebase and example data_input/ and data_output/ directories illustrating the organization and execution of the analytical workflow. Individual scripts identify the corresponding manuscript analyses and figure panels. Raw sequencing data Raw sequencing reads are available through the NCBI Sequence Read Archive under BioProject accession PRJNA1322484.

Beals, Delaney [ORNL] (ORCID:0000000306274574)↗
DOE OSTI2026

Data and Code for: Observation-constrained agroecosystem model inversion reveals continental-scale variation of winter wheat traits

This repository contains the simulation outputs and processing scripts associated with the study of winter wheat traits across the United States, utilizing the Ecosys agroecosystem model. The dataset includes model results for both rainfed and irrigated winter wheat systems, supporting the findings presented in the manuscript titled "Observation-constrained agroecosystem model inversion reveals continental-scale variation of winter wheat traits." Data includes the original Ecosys simulation outputs (archived in .db format within the compressed .zip files) and extracted analysis data (stored in .pkl files for efficient processing). Python code for data processing and figure generation is provided in a Jupyter notebook. External Observational Datasets should refer to the following official repositories for the input and validation data used in this study. The eddy covariance data from the AmeriFlux network (https://ameriflux.lbl.gov/). Climate-forcing data of NLDAS-2 from NASA LDAS (https://ldas.gsfc.nasa.gov/nldas/nldas-2-forcing-data). Soil data from the Gridded Soil Survey Geographic Database (gSSURGO), available at (https://www.nrcs.usda.gov/resources/data-and-reports/gridded-soil-survey-geographic-gssurgo-database). Crop yields, planting and harvest dates from the USDA public databases (https://quickstats.nass.usda.gov/; https://webapp.rma.usda.gov/apps/actuarialinformationbrowser/CropCriteria.aspx). Satellite-derived SLOPE GPP data from ORNL DAAC (https://daac.ornl.gov/cgi-bin/dsviewer.pl?ds_id=1786). Land use and crop progress information from the USDA Crop Data Layer and Crop Progress and Condition Gridded Layers (https://www.nass.usda.gov/Research_and_Science/). The Ecosys model code is available online at https://github.com/jinyun1tang/ECOSYS.

Wheat↗
NASA NTRS1965

Lower Bounds to Energy Eigenvalues for the Stark Effect in a Rigid Rotator

Upper and lower bounds have been calculated for the energy levels of a rigid rotator in an electric field, in order to study the problems associated with the use of the partitioning method for bracketing an eigenvalue of the Schrödinger equation. Results of arbitrarily high accuracy are possible in this example.

Choi, Jong H.↗
NASA NTRS1974

The molecular velocity of sound

The molecular velocity of sound was calculated according to Rao's formula and the temperature and concentration dependences of this value were studied in aqueous solutions of alkali and alkaline-earth halides. Study of relative association brought to light characteristic effects of ions. The variation of the relative association can be explained by a breaking of hydrogen bonds by ions and thermal agitation.

Auslaender, D.↗
NASA NTRS1974

The polyuria of paroxysmal atrial tachycardia

Two patients with paroxysmal atrial fibrillation and an associated polyuria were studied to delineate the mechanism of the increase in urine flow. A striking saluresis was noted in both patients. The increased sodium excretion was probably due to decreased sodium reabsorption, perhaps at proximal tubular nephron sites. This inhibition of sodium reabsorption could explain both the saluresis and some part or all of the polyuria. Re-evaluation of earlier case reports reveals patterns of concomitant salt and water excretion consistent with this mechanism. The saluresis cannot be explained by the previously favored hypothesis of antidiuretic hormone inhibition.

Kinney, M. J.↗
NASA NTRS1974

Requirement for simulation in V/STOL research aircraft programs

The application of flight simulation to aircraft design and development is discussed. The general stages of aircraft development are defined. The application of flight simulation to the following projects is reported: (1) the development and flight research of the Augmented Jet-Flap STOL research aircraft and (2) design studies of advanced VTOL research aircraft. It is stated that the simulation projects proved significant in helping establish criteria for the aircraft design and in facilitating the study of problems associated with new flight profiles, new methods of control, and special emergency conditions.

Quigley, H. C.↗
NASA NTRS1975

Fractography of the high temperature hydrogen attack of a medium carbon steel

Microscopic fracture processes were studied which are associated with hydrogen attack of a medium carbon steel in a well-controlled, high-temperature, high-purity hydrogen environment. Exposure to a hydrogen pressure and temperature of 3.5 MN/m2 and 575 C was found to degrade room temperature tensile properties with increasing exposure time. After 408 hr, yield and ultimate strengths were reduced by more than 40 percent and elongation was reduced to less than 2 percent. Initial fissure formation was found to be associated with manganese rich particles, most probably manganese oxide, aligned in the microstructure during the rolling operation. Fissure growth was found to be associated with a reduction in carbide content of the microstructure and was inhibited by the depletion of carbon. The interior surfaces of sectioned fissures or bubbles exhibit both primary and secondary cracking by intergranular separation. The grain surfaces were rough and rounded, suggesting a diffusion-associated separation process. Specimens that failed at room temperature after exposure to hydrogen were found to exhibit mixed mode fracture having varying amounts of intergranular separation, dimple formation, and cleavage, depending on exposure time.

Melson, H. G.↗
NASA NTRS1976

Measurements of field-aligned currents in a multiple auroral arc system

A rocket-borne experiment to study the currents associated with a system of multiple auroral arcs was conducted at Poker Flat, Alaska, at 1122 UT on Feb. 2, 1972. The magnetic field in the vicinity of the auroral system was measured with a cesium vector magnetometer. Possible configurations were inferred by constructing model current systems that reproduced the magnetic field variations measured along the flight path. The data are interpreted in terms of a model current system consisting of two eastward electrojets and one westward electrojet and three pairs of oppositely directed Birkeland sheet currents, all lying in a plane approximately parallel to the auroral arcs. Sheet thicknesses ranged from 20 to 60 km and current densities from 10 to 45 microampere/sq m; the electrojet currents ranged from 1000 to 2000 A. A possible alternate model consisted of four pairs of sheets whose thicknesses range from 10 to 40 km with current densities from 10 to 90 microampere/sq m. There was quite good agreement between the locations of the visual arcs and the upward current sheets. The overall current configuration is discussed in view of the theoretical models constructed by Atkinson and Sato and Holzer and of other observations.

Sesiano, J.↗
NASA NTRS1977

Feasibility of modern airships - Design definition and performance of selected concepts

Three promising modern airship system concepts and their associated missions were studied: (1) a heavy-lift airship, employing a nonrigid hull and a significant amount of rotor lift, used for short-range transporting and positioning of heavy military and civil payloads; (2) a VTOL (vertical take-off and landing), metal-clad, partially buoyant airship used as a short-haul commercial transport; (3) a fully-buoyant airship used for long-endurance Navy missions. The heavy-lift airship concept offers a dramatic increase in vertical lift capability over existing systems at significantly lower costs per ton-mile. The VTOL airship transport concept appears to be economically competititve with other VTOL aircraft concepts but can attain significantly lower noise levels. The fully-buoyant airship concept can provide an airborne platform with long endurance that satisfies many Navy mission requirements.

Huston, R. R.↗