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At least 577 records · Page 32

Living in Space

In this educational video from the 'Liftoff to Learning' series, astronauts from the STS-56 Mission (Ken Cockrell, Mike Foale, Ellen Ochoa, Steve Oswald, and Ken Cameron) explain and show through demonstrations how microgravity affects the way astronauts live onboard the Space Shuttle, and how these same daily habits or processes differ on Earth. A tour of the Space Shuttle is given, including the sleeping compartments, the kitchen area, the storage compartments, and the Waste Collection System (or WCS, as they call it). Daily habits (brushing teeth, shampooing hair and bathing, eating,...) are explained and actively illustrated, along with reasons of how these applications differ from their employment on Earth.

Ray Brown↗

STS-66 Mission Highlights Resource Tape

This video contains the mission highlights of the STS-66 Space Shuttle Atlantis Mission in November 1994. Astronauts included: Don McMonagle (Mission Commander), Kurt Brown, Ellen Ochoa (Payload Commander), Joe Tanner, Scott Parazynski, and Jean-Francois Clervoy (collaborating French astronaut). Footage includes: pre-launch suitup, entering Space Shuttle, countdown and launching of Shuttle, EVA activities (ATLAS-3, CRISTA/SPAS, SSBUV/A, ESCAPE-2), on-board experiments dealing with microgravity and its effects, protein crystal growth experiments, daily living and sleeping compartment footage, earthviews of various meteorological processes (dust storms, cloud cover, ocean storms), pre-landing and land footage (both from inside the Shuttle and from outside with long range cameras), and tracking and landing shots from inside Mission Control Center. Included is air-to-ground communication between Mission Control and the Shuttle. This Shuttle was the last launch of 1994.

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A comparison of low-gravity measurements on-board Columbia during STS-40

The first NASA Spacelab Life Sciences mission (SLS-1) flew 5 June to 14 June 1991 on the orbiter Columbia (STS-40). The purpose of the mission was to investigate the human body's adaptation to the low-gravity conditions of space flight and the body's readjustment after the mission to the 1g environment of earth. In addition to the life sciences experiments manifested for the Spacelab module, a variety of experiments in other scientific disciplines flew in the Spacelab and in Get Away Special (GAS) Canisters on the GAS Bridge Assembly. Several principal investigators designed and flew specialized accelerometer systems to better assess the results of their experiments by means of a low-gravity environment characterization. This was also the first flight of the NASA Microgravity Science and Applications Division (MSAD) sponsored Space Acceleration Measurement System (SAMS) and the first flight of the NASA Orbiter Experiments Office (OEX) sponsored Orbital Acceleration Research Experiment accelerometer (OARE). We present a brief introduction to seven STS-40 accelerometer systems and discuss and compare the resulting data. During crew sleep periods, acceleration magnitudes in the 10(exp -6) to 10(exp -5)g range were recorded in the Spacelab module and on the GAS Bridge Assembly. Magnitudes increased to the 10(exp -4) level during periods of nominal crew activity. Vernier thruster firings caused acceleration shifts on the order of 10(exp -4)g and primary thruster firings caused accelerations as great as 10(exp -2) g. Frequency domain analysis revealed typical excitation of Orbiter and Spacelab structural modes at 3.5, 4.7, 5.2, 6.2, 7, and 17 Hz.

Rogers, M. J. B.↗

Fatigue in operational settings: Examples from the aviation environment

The need for 24-h operations creates nonstandard and altered work schedules that can lead to cumulative sleep loss and circadian disruption. These factors can lead to fatigue and sleepiness and affect performance and productivity on the job. The approach, research, and results of the NASA Ames Fatigue Countermeasures Program are described to illustrate one attempt to address these issues in the aviation environment. The scientific and operational relevance of these factors is discussed, and provocative issues for future research are presented.

Rosekind, Mark R.↗

Infectious Disease risks associated with exposure to stressful environments

Multiple environmental factors asociated with space flight can increase the risk of infectious illness among crewmembers thereby adversely affecting crew health and mission success. Host defences can be impaired by multiple physiological and psychological stressors including: sleep deprivation, disrupted circadian rhythms, separation from family, perceived danger, radiation exposure, and possibly also by the direct and indirect effects of microgravity. Relevant human immunological data from isolated or stressful environments including spaceflight will be reviewed. Long-duration missions should include reliable hardware which supports sophisticated immunodiagnostic capabilities. Future advances in immunology and molecular biology will continue to provide therapeutic agents and biologic response modifiers which should effectively and selectively restore immune function which has been depressed by exposure to environmental stressors.

Meehan, Ichard T.↗

STS-78 Flight Day 8

On this eighth day of the STS-78 mission, the flight crew, Cmdr. Terence T. Henricks, Pilot Kevin R. Kregel, Payload Cmdr. Susan J. Helms, Mission Specialists Richard M. Linnehan, Charles E. Brady, Jr., and Payload Specialists Jean-Jacques Favier, Ph.D. and Robert B. Thirsk, M.D., continue to conduct experiments primarily focusing on the effects of weightlessness on human physiology. Results from the studies of muscle activity, task performance, and sleep will help future mission planners organize crew schedules for greater efficiency and productivity. For a second consecutive day, Henricks, Kregel, Thirsk, and Favier continue to enter responses to a battery of problem-solving tasks on the Performance Assessment Work Station, a laptop computer.

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Summary Report of Mission Acceleration Measurements for STS-78. Launched June 20, 1996

The microgravity environment of the Space Shuttle Columbia was measured during the STS-78 mission using accelerometers from three different instruments: the Orbital Acceleration Research Experiment, the Space Acceleration Measurement System and the Microgravity Measurement Assembly. The quasi-steady environment was also calculated in near real-time during the mission by the Microgravity Analysis Workstation. The Orbital Acceleration Research Experiment provided investigators with real-time quasi-steady acceleration measurements. The Space Acceleration Measurement System recorded higher frequency data on-board for post-mission analysis. The Microgravity Measurement Assembly provided investigators with real-time quasi-steady and higher frequency acceleration measurements. The Microgravity Analysis Workstation provided calculation of the quasi-steady environment. This calculation was presented to the science teams in real-time during the mission. The microgravity environment related to several different Orbiter, crew and experiment operations is presented and interpreted in this report. A radiator deploy, the Flight Control System checkout, and a vernier reaction control system reboost demonstration had minimal effects on the acceleration environment, with excitation of frequencies in the 0.01 to 10 Hz range. Flash Evaporator System venting had no noticeable effect on the environment while supply and waste water dumps caused excursions of 2 x lO(exp -6) to 4 x 10(exp -6) g in the Y(sub b) and Z(sub b) directions. Crew sleep and ergometer exercise periods can be clearly seen in the acceleration data, as expected. Accelerations related to the two Life Science Laboratory Equipment Refrigerator/Freezers were apparent in the data as are accelerations caused by the Johnson Space Center Projects Centrifuge. As on previous microgravity missions, several signals are present in the acceleration data for which a source has not been identified. The causes of these accelerations are under investigation.

Hakimzadeh, Roshanak↗

Space Acceleration Measurement System (SAMS)/Orbital Acceleration Research Experiment (OARE)

The Life and Microgravity Spacelab (LMS) payload flew on the Orbiter Columbia on mission STS-78 from June 20th to July 7th, 1996. The LMS payload on STS-78 was dedicated to life sciences and microgravity experiments. Two accelerometer systems managed by the NASA Lewis Research Center (LERC) flew to support these experiments, namely the Orbital Acceleration Research Experiment (OARE) and the Space Acceleration Measurements System (SAMS). In addition, the Microgravity Measurement Assembly (NOAA), managed by the European Space Research and Technology Center (ESA/ESTEC), and sponsored by NASA, collected acceleration data in support of the experiments on-board the LMS mission. OARE downlinked real-time quasi-steady acceleration data, which was provided to the investigators. The SAMS recorded higher frequency data on-board for post-mission analysis. The MMA downlinked real-time quasi-steady as well as higher frequency acceleration data, which was provided to the investigators. The Principal Investigator Microgravity Services (PIMS) project at NASA LERC supports principal investigators of microgravity experiments as they evaluate the effects of varying acceleration levels on their experiments. A summary report was prepared by PIMS to furnish interested experiment investigators with a guide to evaluate the acceleration environment during STS-78, and as a means of identifying areas which require further study. The summary report provides an overview of the STS-78 mission, describes the accelerometer systems flown on this mission, discusses some specific analyses of the accelerometer data in relation to the various activities which occurred during the mission, and presents plots resulting from these analyses as a snapshot of the environment during the mission. Numerous activities occurred during the STS-78 mission that are of interest to the low-gravity community. Specific activities of interest during this mission were crew exercise, radiator deployment, Vernier Reaction Control System (VRCS) reboost, venting operations, Flight Control System (FCS) checkout, rack excitation, operation of the Life Sciences Laboratory Equipment Refrigerator/Freezer (LSLE R/F), operation of the JSC Projects Centrifuge, crew sleep, and attitude changes. The low-gravity environment related to these activities is discussed in the summary report.

Hakimzadeh, Roshanak↗

JSC Human Life Sciences Project

This section of the Life and Microgravity Spacelab (LMS) publication includes articles entitled: (1) E029 - Magnetic Resonance Imaging after Exposure to Microgravity; (2) E030 - Extended Studies of Pulmonary Function in Weightlessness; (3) E074 - Direct Measurement of the Initial Bone Response to Spaceflight in Humans; (4) E401 - The Effects of Microgravity on Skeletal Muscle Contractile Properties; (5) E407 - Effects of Microgravity on the Biochemical and Bioenergetic Characteristics of Human Skeletal Muscle; (6) E410 - Torso Rotation Experiment; (7) E920 - Effect of Weightlessness on Human Single Muscle Fiber Function; (8) E948 - Human Sleep, Circadian Rhythms and Performance in Space; (9) E963 - Microgravity Effects on Standardized Cognitive Performance Measures; and (10) E971 - Measurement of Energy Expenditures During Spaceflight Using the Doubly Labeled Water Method

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STS-90 Day 09 Highlights

On this ninth day of the STS-90 mission, the sleep period of the flight crew, Cmdr. Richard A. Searfoss, Pilot Scott D. Altman, and Mission Specialists Richard M. Linnehan, Dafydd Rhys Williams and Kathryn P. Hire, and Payload Specialists Jay C. Buckey and James A. Pawelczyk, is interrupted due to problems with equipment that removes carbon dioxide from the cabin atmosphere. Because of this, Columbia's crew went to bed about two hours later than scheduled.

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STS-90 Day 08 Highlights

On this eighth day of the STS-90 mission, the flight crew, Cmdr. Richard A. Searfoss, Pilot Scott D. Altman, and Mission Specialists Richard M. Linnehan, Dafydd Rhys Williams and Kathryn P. Hire, and Payload Specialists Jay C. Buckey and James A. Pawelczyk continue to operate the 26 individual experiments designed to provide insight into the operation of the nervous system, the most complex and least well-known part of the human body. The STS-90 crew members have used themselves as test subjects in a variety of experiments associated with studying functions such as blood pressure regulation , balance, coordination and sleep patterns. They also have studied a variety of animals to gain additional insight into the effects of the weightless environment of space on the development and performance of the nervous system.

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STS-93 Flight Day 1 Highlights and Crew Activities

On this first day of the STS-93 Columbia mission, the flight crew, Commander Eileen Collins, Pilot Jeff Ashby and Mission Specialists Cady Coleman, Steve Hawley and Michael Tognini deployed the Chandra X-Ray Observatory into space. This was done after a full night of work and preparation. Chandra will study the invisible, and often violent mysteries of x-ray astronomy. Commander Collins maneuvered Columbia to a safe distance away from the telescope as an internal timer counted down to the first of a two-phase ignition of the Inertial Upper Stage. After switching to internal battery power until its solar rays are deployed, the telescope reaches an oval orbit one-third the distance to the Moon to conduct its astronomical observations. Since Chandra is safely on its way and the major objective of their mission is successfully completed, the astronauts end their long day and begin an eight hour sleep period.

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STS-93 Flight Day 2 Highlights and Crew Activities

Following an eight hour sleep period, the five member flight crew, Commander Eileen Collins, Pilot Jeff Ashby, and Mission Specialists Cady Coleman, Steve Hawley and Michael Tognini awakened to begin their second day in space. The main focus of Flight Day 2 activities was to activate the secondary payloads and experiments. Among those efforts was the set-up and first observations using the Southwest Ultraviolet Imaging System (SWUIS), which operates from inside the shuttle cabin. The specific targets observed included the Earth's moon, Mercury, Venus and Jupiter. A break was taken at 4:36 a.m. CDT by Collins and Coleman to do interviews with reporters from 4 major networks.

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Principles and Guidelines for Duty and Rest Scheduling in Commercial Aviation

The aviation industry requires 24-hour activities to meet operational demands. Growth in global long-haul, regional, overnight cargo, and short-haul domestic operations will continue to increase these round-the-clock requirements. Flight crews must be available to support 24-hour-a-day operations to meet these industry demands. Both domestic and international aviation can also require crossing multiple time zones. Therefore, shift work, night work, irregular work schedules, unpredictable work schedules, and dm zone changes will continue to be commonplace components of the aviation industry. These factors pose known challenges to human physiology, and because they result in performance-impairing fatigue, they pose a risk to safety. It is critical to acknowledge and, whenever possible, incorporate scientific information on fatigue, human sleep, and circadian physiology into 24-hour aviation operations. Utilization of such scientific information can help promote crew performance and alertness during flight operations and thereby maintain and improve the safety margin.

Dinges, David F.↗

STS-41D Post Flight Press Conference with Highlights

The crew, Commander Henry W. Hartsfield, Jr., Pilot Michael L. Coats, Mission Specialists Judith A. Resnik, Steven A. Hawley, and Richard M. Mullane, and Payload Specialist Charles D. Walker are seen participating a panel discussion. Live footage of the Press Conference begins with a brief introduction of all the crew, followed by highlights of the flight, a selection of slides and still pictures, and ends with a question and answer segment. The highlights consist of the astronauts walk out to the Astro-Van, panoramic views of the Discovery on the launch pad, main engine start, ignition of the solid rocket boosters, liftoff, and separation of the boosters. Images of the opening of the sun shield and the deployment of the three communication satellites (Satellite Business System (SBS-D), SYNCOM IV-2, and TELSTAR) are also seen. The crew is seen working on experiments, dumping the wastewater, eating supper, and sleeping. Concluding the live footage are slides, and stills of various areas around the world, including the Libyan Desert, Angola, Namibia, and Australia. The Press Conference ends with questions from Houston, NASA Headquarter, Kennedy Space Center, and Marshall Space Flight Center.

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Salivary Pharmacodynamics and Bioavailability of Promethazine in Human Subjects

The acute effects of exposure to microgravity include the development of space motion sickness which usually requires therapeutic intervention. The current drug of choice, promethazine (PMZ), has side effects which include nausea, drowsiness, dizziness, sedation and impaired psychomotor performance. In a ground-based study with commercial airline pilots and shuttle simulator trainers, we measured sleep and psychomotor performance variables, and physiological variables such as blood pressure and heart rate, as a function of circulating drug concentrations in the body. We evaluated a non-invasive sampling method (saliva) as a means of assessing pharmacodynamics following a single intramuscular (IM) dose of PMZ.

Putcha, Lakshmi↗

The Effects of Gravity on the Circadian Timing System

All vertebrates have a physiological control system that regulates the timing of the rhythms of their daily life. Dysfunction of this system, the circadian timing system (CTS), adversely affects an organism's ability to respond to environmental challenges and has been linked to physiological and psychological disorders. Exposure to altered gravitational environments (the microgravity of space and hyperdynamic environments produced via centrifugation) produces changes in both the functioning of the CTS and the rhythmic variables it controls. The earliest record of primate rhythms in a spaceflight environment come from Biosatellite III. The subject, a pig-tailed macaque, showed a loss of synchronization of the body temperature rhythm and a fragmented sleep-wake cycle. Alterations in the rhythm of body temperature were also seen in rhesus macaques flown on COSMOS 1514. Squirrel monkeys exposed to chronic centrifugation showed an initial decrease in the amplitude and mean of their body temperature and activity rhythms. In a microgravity environment, Squirrel monkeys on Spacelab-3 showed a reduction in the mean and amplitude of their feeding rhythms. Since 1992 we have had the opportunity to participate on three US/Russian sponsored biosatellite missions on which a total of six juvenile male rhesus macaques were flown. These animals uniformly exhibited delays in the phasing of their temperature rhythms, but not their heart rate or activity rhythms during spaceflight. There was also a tendency for changes in waveform mean and amplitude. These data suggest that the spaceflight environment may have a differential effect on the different oscillators controlling different rhythmic variables. Ongoing studies are examining the effects of +G on the CTS. The long-term presence of humans in space highlights the need for effective countermeasures to gravitational effects on the CTS.

Fuller, Charles A.↗

Cardiovascular Deconditioning in Humans: Human Studies Core

Major cardiovascular problems, secondary to cardiovascular deconditioning, may occur on extended space missions. While it is generally assumed that the microgravity state is the primary cause of cardiovascular deconditioning, sleep deprivation and disruption of diurnal rhythms may also play an important role. Factors that could be modified by either or both of these perturbations include: autonomic function and short-term cardiovascular reflexes, vasoreactivity, circadian rhythm of cardiovascular hormones (specifically the renin-angiotensin system) and renal sodium handling and hormonal influences on that process, venous compliance, cardiac mass, and cardiac conduction processes. The purpose of the Human Studies Core is to provide the infrastructure to conduct human experiments which will allow for the assessment of the likely role of such factors in the space travel associated cardiovascular deconditioning process and to develop appropriate countermeasures. The Core takes advantage of a newly-created Intensive Physiologic Monitoring (IPM) Unit at the Brigham and Women's Hospital, Boston, MA, to perform these studies. The Core includes two general experimental protocols. The first protocol involves a head down tilt bed-rest study to simulate microgravity. The second protocol includes the addition of a disruption of circadian rhythms to the simulated microgravity environment. Before and after each of these environmental manipulations, the subjects will undergo acute stressors simulating changes in volume and/or stress, which could occur in space and on return to Earth. The subjects are maintained in a rigidly controlled environment with fixed light/dark cycles, activity pattern, and dietary intake of nutrients, fluids, ions and calories.

Williams, Gordon↗