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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 577 records · Page 32

Anticipating Technical Expertise and Capability Evolution in Research Communities Using Dynamic Graph Transformers

The ability to anticipate global technical expertise and capability evolution trends is essential for national and global security, especially in safety-critical domains such as nuclear nonproliferation (NN) and rapidly emerging fields like artificial intelligence (AI). Here, in this work, we extend traditional statistical relational learning approaches (e.g., link prediction in collaboration networks) and formulate a problem of anticipating technical expertise and capability evolution using dynamic heterogeneous graph representations. We develop novel capabilities to forecast collaboration patterns, authorship behavior, and technical capability evolution at different granularities (e.g., scientist and institution levels) in two distinct research fields. We implement a dynamic graph transformer (DGT) neural architecture, which pushes the state-of-the-art graph neural network models by: 1) forecasting heterogeneous (rather than homogeneous) nodes and edges; and 2) relying on both discrete- and continuous-time inputs. We demonstrate that our DGT models predict collaboration, partnership, and expertise patterns with 0.26, 0.73, and 0.53 mean reciprocal rank values for AI and 0.48, 0.93, and 0.22 for NN domains. DGT model performance exceeds the best-performing static graph baseline models by 30%–80% across AI and NN domains. Our findings demonstrate that DGT models boost inductive task performance when previously unseen nodes appear in the test data for the domains with emerging collaboration patterns (e.g., AI). Specifically, models accurately predict which established scientists will collaborate with early career scientists and vice versa in the AI domain.

97 MATHEMATICS AND COMPUTING↗

Galaxy cluster profiles: a Gaussian mixture model approach to halo miscentering

Measurements of the galaxy density and weak-lensing profiles of galaxy clusters typically rely on an assumed cluster center, which is taken to be the brightest cluster galaxy or other proxies for the true halo center defined as the minimum in the potential well. Departure of the assumed cluster center from the true halo center bias the resultant profile measurements, an effect known as miscentering bias. Currently, miscentering is typically modeled in stacked profiles of clusters with a two parameter model. We use an alternate approach in which the profiles of individual clusters are used with the corresponding likelihood computed using a Gaussian mixture model. We test the approach using halos and the corresponding subhalo profiles from the IllustrisTNG hydrodynamic simulations. We obtain significantly improved estimates of the miscentering parameters for both 3D and projected 2D profiles relevant for imaging surveys. We discuss applications to upcoming cosmological surveys. Our Python package for the Gaussian mixture model is publicly available at https://github.com/KyleMiller1/Halo-Miscentering-Mixture-Model.

Bayesian reasoning↗

The Impacts of Rotational Mixing on the Precipitation Simulated by a Convection Permitting Model

With increased availability of computational resources, regional and global scale convection-permitting model (CPM, Δx ~ 1–10 km) simulations are becoming more common. CPMs have improved accuracy in their representation of deep convection and mesoscale convective systems (MCSs) compared to coarser resolution models. However, CPMs still exhibit convective cloud and precipitation biases relative to observations, notably a lesser frequency of light precipitation rates and greater frequency of heavy precipitation rates. In this work we hypothesize that these CPM biases are related to under-resolved mixing between convective updrafts and their surrounding environment. To test this hypothesis, we introduce a parameterization to the Weather Research and Forecasting model (WRF) that adds a small angular rotation of the grid-scale flow about the axis perpendicular to the plane of convective drafts. This rotated flow is then allowed to alter advection of moisture and hydrometeors. The effects of such mixing on precipitation characteristics are evaluated in month-long 4-km grid spacing simulations over the Amazon. The enhanced mixing transports moisture and condensate from convective cores to other areas including downdrafts. This increases the frequency of low-precipitable water and light precipitation. It also decreases the frequency of intense precipitation from isolated deep convection and MCSs, increases cloud top temperatures, reduces radar echo-top heights, and increases overall precipitation by altering the relationship of precipitation with precipitable water, in better agreement with observations. The results suggest when optimized using multiple observations, such an approach may provide a path toward more accurate representation of convection and precipitation statistics in convection-permitting simulations.

54 ENVIRONMENTAL SCIENCES↗

Statistical Techniques For Real-time Anomaly Detection Using Spark Over Multi-source VMware Performance Data

Anomaly detection refers to the identi cation of an irregular or unusual pat- tern which deviates from what is standard, normal, or expected. Such deviated patterns typically correspond to samples of interest and are assigned different labels in different domains, such as outliers, anomalies, exceptions, or malware. Detecting anomalies in fast, voluminous streams of data is a formidable chal- lenge. This paper presents a novel, generic, real-time distributed anomaly detection framework for heterogeneous streaming data where anomalies appear as a group. We have developed a distributed statistical approach to build a model and later use it to detect anomaly. As a case study, we investigate group anomaly de- tection for a VMware-based cloud data center, which maintains a large number of virtual machines (VMs). We have built our framework using Apache Spark to get higher throughput and lower data processing time on streaming data. We have developed a window-based statistical anomaly detection technique to detect anomalies that appear sporadically. We then relaxed this constraint with higher accuracy by implementing a cluster-based technique to detect sporadic and continuous anomalies. We conclude that our cluster-based technique out- performs other statistical techniques with higher accuracy and lower processing time.

Apache Spark↗

Hydrogen Leak Modeling for Development of Smart Distributed Monitoring Under Unintended Releases

Hydrogen is a versatile and clean energy carrier that can be produced from various renewable sources such as wind, solar, and hydropower. Hydrogen has the potential to play a crucial role in decarbonizing industrial processes that are currently reliant on fossil fuels and provide long-duration and/or seasonal energy storage to enable electricity decarbonization. Hydrogen can also be used as a fuel for fuel cell vehicles, providing a zero-emission alternative to traditional internal combustion engines. DOE launched the Hydrogen Energy Earthshot (Hydrogen Shot) in June 2021 to reduce the cost of clean hydrogen by 80% to $1 per 1 kilogram in 1 decade ("1 1 1"). While promising, Hydrogen is highly-flammable, and in the presence of oxygen, it can form explosive mixtures. . Therefore, understanding leak scenarios is essential to evaluate and mitigate the safety risks associated with potential hydrogen leaks. An increased understanding of leak behavior, and having tools to model leaks, can help assess how hydrogen would disperse in different environments, influencing emergency response plans and safety measures, and identify potential issues with materials and design systems that can withstand the challenges posed by hydrogen. Recently, researchers have attempted to study hydrogen leaks for development of risk management strategies. However, the focus has been on closed or semi-closed spaces like storage rooms, vehicles, garages, and fueling stations - all promising locations for future hydrogen infrastructure. In this presentation, the modeling environment extends the span of research further by modeling hydrogen leak in an outdoor, open space. We will present the key challenges with modeling hydrogen leaks in an uncontrollable environment, how they were handled, and how modeling results informed sensor selection and placement. A Hydrogen research facility at the National Renewable Energy Laboratory (NREL) was used as a case study to model hydrogen leaks. In the future, Hydrogen wide area detection methodologies will be developed and tested at this site to monitor for unintended and operational hydrogen releases. The data generated from modeling will be used to develop a predictive model to detect hydrogen leak location based on concentration measured by sensors in this open space. Furthermore, the facility was also chosen because controlled hydrogen releases can be performed. A computational fluid dynamics (CFD) based modeling approach was taken to model hydrogen leak. The full-scale hydrogen facility was modeled with a large ambient domain. The electrolyzer at the facility can produce a controlled release rate of 27 kg-H2/hr. Site-specific atmospheric and weather condition data such as wind direction, wind speed at various altitudes, and temperature were used as inputs to the model. To capture the variability of weather conditions, a subset of the weather conditions experienced during daytime hours without precipitation over the course of three months was generated; using established data clustering techniques, a total of 100 condition sets were chosen. The results show statistical distributions and ranges of hydrogen concentrations at locations throughout the domain. These distributions are compared to experimental data from a constant mass flow, controlled hydrogen release at the facility. The stochastic wind conditions of the release make direct validation difficult, therefore, statistical comparison approaches were used. Wind conditions are found to significantly impact the release behavior, including direction and concentration. Sensor selection and placement is proposed for the facility and is now based on release behavior predicted for the facility given its weather patterns; this is much more informed than without the modeling results. The methodology and analysis procedure can be translated to other facilities using modified geometries and site-specific weather conditions. Hydrogen holds great promise as a renewable energy fuel, but ensuring safety in its production, storage, and use is paramount. Studying potential leak scenarios in an open space will help develop sensors to detect hydrogen on a large spectrum of concentration and eventually build a smart distributed monitoring system.

CFD↗

Monitoring and prediction of porosity in laser powder bed fusion using physics-informed meltpool signatures and machine learning

In this work we accomplished the monitoring and prediction of porosity in laser powder bed fusion (LPBF) additive manufacturing process. This objective was realized by extracting physics-informed meltpool signatures from an in-situ dual-wavelength imaging pyrometer, and subsequently, analyzing these signatures via computationally tractable machine learning approaches. Porosity in LPBF occurs despite extensive optimization of processing conditions due to stochastic causes. Hence, it is essential to continually monitor the process with in-situ sensors for detecting and mitigating incipient pore formation. In this work a tall cuboid-shaped part (10 mm × 10 mm × 137 mm, material ATI 718Plus) was built with controlled porosity by varying laser power and scanning speed. This test caused various types of porosity, such as lack-of-fusion and keyhole formation, with varying degrees of severity in the part. The meltpool was continuously monitored using a dual-wavelength imaging pyrometer installed in the machine. Physically intuitive process signatures, such as meltpool length, temperature distribution, and ejecta (spatter) characteristics, were extracted from the meltpool images. Subsequently, relatively simple machine learning models, e.g., K-Nearest Neighbors, were trained to predict both the severity and type of porosity as a function of these physics-informed meltpool signatures. These models resulted in a prediction accuracy exceeding 95% (statistical F1-score). The same analysis was carried out with a complex, black-box deep learning convolutional neural network which directly used the meltpool images instead of physics-informed features. The convolutional neural network produced a comparable F1-score in the range of 89–97%. Finally, these results demonstrate that using pragmatic, physics-informed meltpool signatures within a simple machine learning model is as effective for flaw prediction in LPBF as using a complex and computationally demanding black-box deep learning model.

36 MATERIALS SCIENCE↗

Wave-function-based emulation for nucleon-nucleon scattering in momentum space

Emulators for low-energy nuclear physics can provide fast and accurate predictions of bound-state and scattering observables for applications that require repeated calculations with different parameters, such as Bayesian uncertainty quantification. In this paper, we extend a scattering emulator based on the Kohn variational principle (KVP) to momentum space (including coupled channels) with arbitrary boundary conditions, which enable the mitigation of spurious singularities known as Kohn anomalies. We test it on a modern chiral nucleon-nucleon (N N) interaction, including emulation of the coupled channels. We provide comparisons between a Lippmann-Schwinger equation emulator and our KVP momentum-space emulator for a representative set of neutron-proton (n p) scattering observables, and also introduce a quasi-spline-based approach for the KVP-based emulator. Furthermore, our findings show that while there are some trade-offs between accuracy and speed, all three emulators perform well. Self-contained Jupyter notebooks that generate the results and figures in this paper are publicly available.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗

Design of machine learning models with domain experts for automated sensor selection for energy fault detection

Data-driven techniques that extract insights from sensor data reduce the cost of improving system energy performance through fault detection and system health monitoring. To lower cost barriers to widespread deployment, a methodology is proposed that takes advantage of existing sensor data, encodes expert knowledge about the application system to create ‘virtual sensors’ and applies statistical and mathematical methods to reduce the time required for manual configurations. The approach combines sensor data points with encoded expert knowledge that is generic to the application system but independent of a particular deployment, thereby reducing the need to tailor to individual deployments. Additionally, this paper not only presents a method that detects faults from measured energy data, but also (1) describes an engagement method with experts in the energy system domain to identify data, (2) integrates domain knowledge with the data, (3) automatically selects from among the large pool of potential input data, and (4) uses machine learning to automatically build a data-driven fault detection model. Demonstration on a commercial building chiller plant shows that only a small number of virtual sensors is necessary for fault detection with high accuracy rates. This corresponds to the use of only five out of 52 original sensor data points features. With as few as four features, classification F1 scores exceed 90% on the training set and 80% on the testing set. The results are implementable and realizable using off-the-shelf tools. The goal is to design with domain experts an energy monitoring system that can be configured once and then widely deployed with little additional cost or effort.

47 OTHER INSTRUMENTATION↗

Multifidelity validation of digital surrogates using variable-density turbulent mixing models

In this study, ensembles of experimental data are presented and utilized to compare and validate two models used in the simulation of variable-density (Atwood = 0.22), compressible turbulent mixing. Though models of this kind (Reynolds averaged NavierStokes and large-eddy simulations) have been validated extensively with more canonical flows in previous studies, here the present approach offers novelty in the complexity of the geometry, the ensemble-based validation, and the uniformity of the computational framework on which the models are tested. Moreover, all experimental and computational tasks were completed by the authors which has led to a tightly coupled experimental configuration with its “digital twin.” The experimental divergent-shock-tube facility and its data acquisition methods are described and replicated in simulation space. A 2D Euler model which neglects the turbulent mixing at the interface is optimized to experimental data using a Gaussian process. This model then serves as the basis for both the 2D RANS and 3D LES studies that make comparisons to the mixing-layer data from the experiment. A relatively simple RANS model is shown to produce good agreement with experimental data only at late flow development times. The LES ensembles generally show good agreement with experimental data but display sensitivity to the characterization of initial conditions. Resolution-dependent behavior is also observed for certain higher-order statistics of interest. Overall, the LES model successfully captures the effects of divergent geometry, compressibility, and combined nonlinear instabilities inherent to the problem. The successful prediction of mixing width and its growth rate highlight the existence of three distinct regimes in the development of the instability, each with similarities to previously studied instabilities.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

A Multi-Sensor Approach for Measuring Bird and Bat Collisions with Offshore Wind Turbines (Final Technical Report)

Collision of birds and bats with wind turbines is a conservation concern for both land-based and offshore wind projects. The fatality rates of birds and bats at land-based turbines are well documented. The measurement strategies on land focus on finding carcasses following collision, estimating the number of carcasses missed through searcher efficiency, carcass persistence trials and carcass fall distributions, and modeling statistically robust fatality rates. Few technologies have been developed to monitor offshore bird and bat collisions, and many that have been developed focused on detecting collisions with large birds. The few studies that have attempted to document collisions at offshore turbines do not account for smaller bodied animals or for collisions that might be missed, which prevents the calculation of statistically robust fatality rates. The overall goal of this report, A Multi-Sensor Approach for Measuring Bird and Bat Collisions with Offshore Wind Turbines (Project), was to develop an effective multi-sensor system for quantifying bird and bat collision rates, specifically for offshore wind facilities. The Project goal and resulting automated collision detection system was achieved through two major technological advancements: 1) refining The Netherlands Organisation for Applied Scientific Research’s (TNO’s) existing WT-Bird® vibration sensing system, that had successfully detected large bird collisions during daytime, to allow for improved detection of smaller birds and bats during both daytime and nighttime hours and 2) improving image processing systems and developing and integrating machine learning algorithms to automatically detect and classify small and large bird and bat collisions with offshore turbines. This final technical report (FTR) summarizes Methods , Results , Conclusions , and Lessons Learned during each of the five Tasks identified for this research and development effort. This FTR includes summaries of the following: Task 1. Initial Engineering Tests to Improve WT-Bird® Task 2. Installation of WT‐Bird® on a Utility-scale Turbine at the National Wind Technology Center – National Renewable Energy Laboratory Task 3. Field Tests and Refinement of the Object Detection System Task 4. Validation of WT-Bird® on a Land-based Turbine Task 5. Preparation for the Implementation of WT-Bird® on an Offshore Turbine. This research and development effort documented successful improvement of the WT Bird® collision detection system to detect small birds and bats, and WT-Bird® is the first collision detection system to validate results compared to land-based post-construction monitoring. The collision trials provide estimates of missed targets that can be used to estimate fatality rates, a significant improvement relative to other offshore collision monitoring systems. Advances were made in developing an edge-processing solution to reduce data storage requirements, which is important if the system is deployed for long periods of time at offshore turbines. The improved WT-Bird® system also provides an important option for wind operators on land or offshore who need to document specific details about when collisions occur, particularly efforts to further research on bat impact minimization, or when standard fatality searches are impractical (e.g. offshore) or inadequate (e.g. challenging locations on land).

17 WIND ENERGY↗

Leveraging Intrinsic Principal Directions for Multifidelity Uncertainty Quantification

In this work we propose an approach for accelerating Uncertainty Quantification (UQ) analysis in the context of Multifidelity applications. In the presence of complex multiphysics applications, which often require a prohibitive computational cost for each evaluation, multifidelity UQ techniques try to accelerate the convergence of statistics by leveraging the in- formation collected from a larger number of a lower fidelity model realizations. However, at the-state-of-the-art, the performance of virtually all the multifidelity UQ techniques is related to the correlation between the high and low-fidelity models. In this work we proposed to design a multifidelity UQ framework based on the identification of independent important directions for each model. The main idea is that if the responses of each model can be represented in a common space, this latter can be shared to enhance the correlation when the samples are drawn with respect to it instead of the original variables. There are also two main additional advantages that follow from this approach. First, the models might be correlated even if their original parametrizations are chosen independently. Second, if the shared space between models has a lower dimensionality than the original spaces, the UQ analysis might benefit from a dimension reduction standpoint. In this work we designed this general framework and we also tested it on several test problems ranging from analytical functions for verification purpose, up to more challenging application problems as an aero-thermo-structural analysis and a scramjet flow analysis.

42 ENGINEERING↗

Hemispherical power asymmetry in intensity and polarization for Planck PR4 data

Abstract One of the foundations of the Standard Model of Cosmology is statistical isotropy, which can be tested, among other probes, through the study of the Cosmic Microwave Background (CMB). However, a hemispherical power asymmetry on large scales has been reported for WMAP and Planck data by different works.The statistical significance is above 3σfor temperature, suggesting a directional dependence of the local power spectrum, and thus a feature beyond the ΛCDM model. With the third release of the Planck data (PR3), a new analysis was performed including the E-mode polarization maps, finding an asymmetry at a modest level of significance. In this work, we perform an asymmetry analysis in intensity and polarization maps for the latest Planck processing pipeline (PR4). We obtain similar results to those obtained with PR3, with a slightly lower significance (2.8% for the Sevem method)for the amplitude of the E-mode local variance dipole as well as a significant variability with the considered mask.In addition, a hint of a possible T-E alignment between the asymmetry axes is found at the level of ∼ 5%. For the analysis, we have implemented an alternative inpainting approach in order to get an accurate reconstruction of the E-modes. More sensitive all-sky CMB polarization data, such as those expected from the future LiteBIRD experiment, are needed to reach a more robust conclusion on the possible existence of deviations from statistical isotropy in the form of a hemispherical power asymmetry.

Astronomy & Astrophysics↗

Continental Scale Hydrostratigraphy: Comparing Geologically Informed Data Products to Analytical Solutions

Abstract This study synthesizes two different methods for estimating hydraulic conductivity (K) at large scales. We derive analytical approaches that estimate K and apply them to the contiguous United States. We then compare these analytical approaches to three‐dimensional, national gridded K data products and three transmissivity (T) data products developed from publicly available sources. We evaluate these data products using multiple approaches: comparing their statistics qualitatively and quantitatively and with hydrologic model simulations. Some of these datasets were used as inputs for an integrated hydrologic model of the Upper Colorado River Basin and the comparison of the results with observations was used to further evaluate the K data products. Simulated average daily streamflow was compared to daily flow data from 10 USGS stream gages in the domain, and annually averaged simulated groundwater depths are compared to observations from nearly 2000 monitoring wells. We find streamflow predictions from analytically informed simulations to be similar in relative bias and Spearman's rho to the geologically informed simulations. R ‐squared values for groundwater depth predictions are close between the best performing analytically and geologically informed simulations at 0.68 and 0.70 respectively, with RMSE values under 10 m. We also show that the analytical approach derived by this study produces estimates of K that are similar in spatial distribution, standard deviation, mean value, and modeling performance to geologically‐informed estimates. The results of this work are used to inform a follow‐on study that tests additional data‐driven approaches in multiple basins within the contiguous United States.

54 ENVIRONMENTAL SCIENCES↗

Soil and water conservation using the socioeconomics, sustainability concerns, and policy preference for residual biomass harvest

While woody bioenergy opens up a new market opportunity for residual biomass, overharvesting of residual biomass can adversely affect soil health, water quality, timber health and stand productivity, among others. As such, it is important to understand the proportion of residual biomass forestland owners are willing to leave unharvested for soil nutrient and other environmental benefit purposes, their sustainability concerns, and policy preferences. Toward this end, we conducted a mail survey on 900 randomly selected forestland owners in Virginia and used ordinal logistic regression, cluster analyses, and Cochran-Armitage trend tests to analyze the data. Our analyses of the 121 most complete responses suggest that factors such as ownership tenure, mode of land acquisition, size of forestland, and forestland own- ership objectives, among other factors, affect decisions regarding the proportion of residual biomass forestland owners choose to leave unharvested. Analyses of landowners’ sustainability concerns indicate a clustering pattern, where concerns about sufficiency of best management practices and the potential implications of harvest decision on soil and water quality are among the statistical representatives of their respective clusters. Respondents likely to engage in harvest practices that do not leave any residual biomass on the ground have a preference for policies that help cover management cost. Decision makers administering or considering such policy proposals should be aware of the inadvertent effect such cost sharing arrange- ments can have in encouraging unsustainable practices.These results also hint at the potential need for combining such cost sharing arrangements with extension and outreach programs. Lastly, by accounting for landowners’ concerns and preferences, this study complements previous studies that primarily adopt engineering based approaches and solutions.

bioenergy↗

The Correlation between Halo Mass and Stellar Mass for the Most Massive Galaxies in the Universe

We present measurements of the clustering of galaxies as a function of their stellar mass in the Baryon Oscillation Spectroscopic Survey. We compare the clustering of samples using 12 different methods for estimating stellar mass, isolating the method that has the smallest scatter at fixed halo mass. In this test, the stellar mass estimate with the smallest errors yields the highest amplitude of clustering at fixed number density. We find that the PCA stellar masses of Chen et al. clearly have the tightest correlation with halo mass. The PCA masses use the full galaxy spectrum, differentiating them from other estimates that only use optical photometric information. Using the PCA masses, we measure the large-scale bias as a function of M{sub ∗} for galaxies with logM{sub ∗}⩾11.4, correcting for incompleteness at the low-mass end of our measurements. Using the abundance matching ansatz to connect dark matter halo mass to stellar mass, we construct theoretical models of b(M{sub ∗}) that match the same stellar mass function but have different amounts of scatter in stellar mass at fixed halo mass, σ{sub logM∗}. Using this approach, we find σ{sub logM∗}=0.18{sub −0.02}{sup +0.01}. This value includes both intrinsic scatter as well as random errors in the stellar masses. To partially remove the latter, we use repeated spectra to estimate statistical errors on the stellar masses, yielding an upper limit to the intrinsic scatter of 0.16 dex.

79 ASTRONOMY AND ASTROPHYSICS↗

A machine learning approach for efficient multi-dimensional integration

Many physics problems involve integration in multi-dimensional space whose analytic solution is not available. The integrals can be evaluated using numerical integration methods, but it requires a large computational cost in some cases, so an efficient algorithm plays an important role in solving the physics problems. We propose a novel numerical multi-dimensional integration algorithm using machine learning (ML). After training a ML regression model to mimic a target integrand, the regression model is used to evaluate an approximation of the integral. Then, the difference between the approximation and the true answer is calculated to correct the bias in the approximation of the integral induced by ML prediction errors. Because of the bias correction, the final estimate of the integral is unbiased and has a statistically correct error estimation. Three ML models of multi-layer perceptron, gradient boosting decision tree, and Gaussian process regression algorithms are investigated. The performance of the proposed algorithm is demonstrated on six different families of integrands that typically appear in physics problems at various dimensions and integrand difficulties. The results show that, for the same total number of integrand evaluations, the new algorithm provides integral estimates with more than an order of magnitude smaller uncertainties than those of the VEGAS algorithm in most of the test cases.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

TU-AB-202-11: Tumor Segmentation by Fusion of Multi-Tracer PET Images Using Copula Based Statistical Methods

Purpose: Multi-tracer PET imaging is getting more attention in radiotherapy by providing additional tumor volume information such as glucose and oxygenation. However, automatic PET-based tumor segmentation is still a very challenging problem. We propose a statistical fusion approach to joint segment the sub-area of tumors from the two tracers FDG and FMISO PET images. Methods: Non-standardized Gamma distributions are convenient to model intensity distributions in PET. As a serious correlation exists in multi-tracer PET images, we proposed a new fusion method based on copula which is capable to represent dependency between different tracers. The Hidden Markov Field (HMF) model is used to represent spatial relationship between PET image voxels and statistical dynamics of intensities for each modality. Real PET images of five patients with FDG and FMISO are used to evaluate quantitatively and qualitatively our method. A comparison between individual and multi-tracer segmentations was conducted to show advantages of the proposed fusion method. Results: The segmentation results show that fusion with Gaussian copula can receive high Dice coefficient of 0.84 compared to that of 0.54 and 0.3 of monomodal segmentation results based on individual segmentation of FDG and FMISO PET images. In addition, high correlation coefficients (0.75 to 0.91) for the Gaussian copula for all five testing patients indicates the dependency between tumor regions in the multi-tracer PET images. Conclusion: This study shows that using multi-tracer PET imaging can efficiently improve the segmentation of tumor region where hypoxia and glucidic consumption are present at the same time. Introduction of copulas for modeling the dependency between two tracers can simultaneously take into account information from both tracers and deal with two pathological phenomena. Future work will be to consider other families of copula such as spherical and archimedian copulas, and to eliminate partial volume effect by considering dependency between neighboring voxels.

60 APPLIED LIFE SCIENCES↗

Antarctic ice sheet model comparison with uncurated geological constraints shows that higher spatial resolution improves deglacial reconstructions

Accurately reconstructing past changes to the shape and volume of the Antarctic ice sheet relies on the use of physically based and thus internally consistent ice sheet modeling, benchmarked against spatially limited geologic data. The challenge in model benchmarking against geologic data is diagnosing whether model-data misfits are the result of an inadequate model, inherently noisy or biased geologic data, and/or incorrect association between modeled quantities and geologic observations. In this work we address this challenge by (i) the development and use of a new model-data evaluation framework applied to an uncurated data set of geologic constraints, and (ii) nested high-spatial-resolution modeling designed to test the hypothesis that model resolution is an important limitation in matching geologic data. While previous approaches to model benchmarking employed highly curated datasets, our approach applies an automated screening and quality control algorithm to an uncurated public dataset of geochronological observations (specifically, cosmogenic-nuclide exposure-age measurements from glacial deposits in ice-free areas). This optimizes data utilization by including more geological constraints, reduces potential interpretive bias, and allows unsupervised assimilation of new data as they are collected. We also incorporate a nested model framework in which high-resolution domains are downscaled from a continent-wide ice sheet model. We highlight the application of this framework by applying these methods to a small ensemble of deglacial ice-sheet model simulations, and demonstrate that the nested approach improves the ability of model simulations to match exposure age data collected from areas of complex topography and ice flow. We develop a range of diagnostic model-data comparison metrics to provide more insight into model performance than possible from a single-valued misfit statistic, showing that different metrics capture different aspects of ice sheet deflation.

Geosciences↗