Search NASA⌕ Search

SEARCH · Search NASA

Results for “programmable”

Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 595 records · Page 33
All sourcesNASA NTRSDOE OSTI
DOE OSTI2023

South Africa: Framework for Energy Efficiency Demand Side Management

In July 2022, President Cyril Ramaphosa announced an emergency response plan to address the growing electricity crisis in South Africa, which included the necessity for customers of Eskom, South Africa’s primary electricity supplier, to implement demand-side energy efficiency measures. This report is the second of two reports that provides the foundation for a strategic Demand-Side Management (DSM) approach to reduce load shedding and maximize energy savings in South Africa, though inter-governmental collaboration and increased coordination of energy efficiency activities. The first report focuses on the experience of Eskom’s rate-funded Integrated Demand Management (IDM) programme, from its beginning in 2004 to today, highlighting the factors that led to failed support for the programme. This second report focuses on addressing the challenges identified in the first report and describes the elements of a policy framework to develop a sustained DSM program to meet the government’s energy efficiency goals in terms of greenhouse gas emissions reduction and social equity and inclusion to achieve a just transition.

24 POWER TRANSMISSION AND DISTRIBUTION↗
DOE OSTI2023

South Africa: Energy Efficiency Demand Side Management Experience (2004-2022)

In July 2022, President Cyril Ramaphosa announced an emergency response plan to address the growing electricity crisis in South Africa, which included the necessity for customers of Eskom, South Africa’s primary electricity supplier, to implement demand-side energy efficiency measures. This report is the first of two reports that provides the foundation for a strategic Demand-Side Management (DSM) approach to reduce load shedding and maximize energy savings in South Africa, through inter-governmental collaboration and increased coordination of energy efficiency activities. This first report focuses on the experience of Eskom’s rate-funded Integrated Demand Management (IDM) programme, from its beginning in 2004 to today, highlighting the factors that led to failed support for the programme, and emphasizing the measures that will need to be addressed to meet the government’s energy efficiency (EE) goals, as well as other socio-economic and environmental priorities, such as job creation, affordability and greenhouse gas (GHG) emission reduction goals.

29 ENERGY PLANNING, POLICY, AND ECONOMY↗
DOE OSTI2025

Microbial Community Analysis & Functional Evaluation in Soils

The overall objective of this proposal was to develop technologies to alter the composition and function of important members of microbial communities. In particular, the overall objective of the microbial community editing portion of the proposal focuses on developing foundational tools and understanding required to predict, alter and design grass rhizosphere communities impacting DOE missions. Specifically, the project is centered on the Microbial Community Analysis & Functional Evaluation in Soils (m-CAFES) to manipulate microbial consortia associated with plants of interest for the bioenergy sector, under the presumption that bacterial communities can be manipulated to enhance plant health. For tasks of specific interest to us, we are focusing on developing novel Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) based technologies (primarily focusing on Aim 1) and their delivery modalities (notably subaim 1.2) to edit specific bacterial genomes of interest to enhance their functionalities, and programmably ablate specific undesirable members of bacterial communities for plant health. We are focusing on engineering bacteriophages (bacterial viruses, for subaim 1.2) to carry programmable CRISPR-Cas systems (subaim 1.1) to target (ablate) or alter (edit) genomes of interest. This will enable us to carry out microbial perturbations that will impact community composition and function and ultimately plant growth and health, to enable the next phase of the project by deploying them in situ (subaims 1.3 and 1.4).

59 BASIC BIOLOGICAL SCIENCES↗
DOE OSTI2025

Studying Open Quantum Systems Relevant to Chemistry on a Trapped-Ion Quantum Simulator (Final Technical Report)

This project advances the trapped-ion quantum simulator as a versatile platform for studying open quantum system phenomena. We aim to contribute to the emerging quantum simulation toolkits and enable simulation of nanoscale energy processes. Trapped-ion platforms offer unique capabilities: their vibrational motion can be precisely manipulated, measured, and coherently coupled to auxiliary qubits. The vibrational mode can function both as a highly sensitive quantum sensor and a programmable environment bath. Using this platform, we achieved three major outcomes. First, we demonstrated using the vibrational mode as an ultrasensitive probe for testing fundamental physics, including possible nonlinear quantum mechanics effects. Second, we established that these modes can act as controllable baths in which tunable noise and loss can enhance or modify energy-transfer dynamics, providing the experimental preparation toward studying mechanisms relevant to chemical reactions and light-harvesting systems. Third, by introducing controllable nonlinear gain and loss, we showed theoretically how simulations using trapped ions can model vibrationally-assisted energy transport in a non‐Hermitian quantum system comprising a chromophore dimer weakly coupled to a vibrational mode. Exploring the non‐Hermitian dynamics of the whole system including vibrations, we found that energy transfer accompanied by absorption of phonons from a vibrational mode can be significantly enhanced near an exceptional point. This theoretical work on simulation of energy transfer processes in driven non‐Hermitian quantum systems revealed an interesting novel path to study open quantum systems dynamics under conditions of gain and loss. We then further explored the benefits of controllable gain and loss with an experimental realization of quantum analogs of nonlinear oscillators, namely, the van der Pol oscillator. Here we observed mutual synchronization mediated by collective dissipation between two oscillators. In parallel, we explored related quantum networking protocols using the same trapped-ion platform, developing fast, high-fidelity schemes for distributing entanglement. Together, these achievements show that trapped-ion vibrational modes provide a highly programmable and high-fidelity platform for investigating complex dissipative quantum behavior, while enabling new approaches to remote quantum sensing, energy science, and nonlinear quantum dynamics.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗
DOE OSTI2024

Portable Parallel Algorithms and Frameworks for Exascale Graph Analytics

Graphs (or networks) are a tool used to model the interactions among various entities. Efficiently processing large graphs has recently attracted significant attention due to the applications of graphs in various domains, such as biology, chemistry, and cyber-security. Analyzing the structure and properties of these graphs is an important component of many scientific computing pipelines. With the explosion in the volume of data, graphs have become very large and can contain hundreds of billions of vertices and trillions of edges. Therefore, it is crucial to develop high-performance methods to enable graph analysis to be done quickly and energy-efficiently. Furthermore, these solutions should be highly parallel in order to take advantage of modern parallel machines. However, designing efficient solutions is not enough. With the wide variety of computing environments available, each with different programmability and performance characteristics, it is necessary to develop solutions that are portable in terms of both performance (i.e., provide theoretical guarantees) and programmability (i.e., provide high level abstractions).

97 MATHEMATICS AND COMPUTING↗
DOE OSTI2022

Chapter 5: Bright muon beams and muon colliders

The muon collider offers a path toward high-energy, high-luminosity lepton collisions that extends beyond the expected reach of electron-positron colliders and would be competitive in physics reach with proton colliders at the highest energies. Nonetheless, several challenging elements of muon collider technology must be more fully addressed to achieve a maturity level commensurate with linear colliders. In this chapter, the potential benefits of a muon collider in terms of cost, sustainability and timescale are outlined. The major remaining technical challenges are described and an R&D programme is outlined. This programme, assuming suitable funding, will enable the next Update of the European Strategy for Particle Physics to make informed decisions regarding the future R&D path for lepton colliders.

43 PARTICLE ACCELERATORS↗
DOE OSTI2017

Engineering the Bacterial Microcompartment Domain for Molecular Scaffolding Applications

As synthetic biology advances the intricacy of engineered biological systems, the importance of spatial organization within the cellular environment must not be marginalized. Increasingly, biological engineers are investigating means to control spatial organization within the cell, mimicking strategies used by natural pathways to increase flux and reduce cross-talk. A modular platform for constructing a diverse set of defined, programmable architectures would greatly assist in improving yields from introduced metabolic pathways and increasing insulation of other heterologous systems. Here, we review recent research on the shell proteins of bacterial microcompartments and discuss their potential application as “building blocks” for a range of customized intracellular scaffolds. As a result, we summarize the state of knowledge on the self-assembly of BMC shell proteins and discuss future avenues of research that will be important to realize the potential of BMC shell proteins as predictively assembling and programmable biological materials for bioengineering.

metabolic engineering↗
DOE OSTI2024

Entropy Analysis of FPGA Interconnect and Switch Matrices for Physical Unclonable Functions

Random variations in microelectronic circuit structures represent the source of entropy for physical unclonable functions (PUFs). In this paper, we investigate delay variations that occur through the routing network and switch matrices of a field-programmable gate array (FPGA). The delay variations are isolated from other components of the programmable logic, e.g., look-up tables (LUTs), flip-flops (FFs), etc., using a feature of Xilinx FPGAs called dynamic partial reconfiguration (DPR). A set of partial designs is created to fix the placement of a time-to-digital converter (TDC) and supporting infrastructure to enable the path delays through the target interconnect and switch matrices to be extracted by subtracting out common-mode delay components. Delay variations are analyzed in the different levels of routing resources available within FPGAs, i.e., local routing and across-chip routing. Data are collected from a set of Xilinx Zynq 7010 devices, and a statistical analysis of within-die variations in delay through a set of the randomly-generated and hand-crafted interconnects is presented.

97 MATHEMATICS AND COMPUTING↗
DOE OSTI2016

Transient Biocompatible Polymeric Platforms for Long-Term Controlled Release of Therapeutic Proteins and Vaccines

Polymer-based interpenetrating networks (IPNs) with controllable and programmable degradation and release kinetics enable unique opportunities for physisorption and controlled release of therapeutic proteins or vaccines while their chemical and structural integrities are conserved. This paper presents materials, a simple preparation method, and release kinetics of a series of long-term programmable, biocompatible, and biodegradable polymer-based IPN controlled release platforms. Release kinetics of the gp41 protein was controlled over a 30-day period via tuning and altering the chemical structure of the IPN platforms. Post-release analysis confirmed structural conservation of the gp41 protein throughout the process. Cell viability assay confirmed biocompatibility and non-cytotoxicity of the IPNs.

Materials Science↗
DOE OSTI2020

Dynamically Reconfigurable Data Readout of Pixel Detectors for Automatic Synchronization with Data Acquisition Systems

Reconfigurable detectors with dynamically selectable sensing and readout modes are highly desirable for implementing edge computing as well as enabling advanced imaging techniques such as foveation. The concept of a camera system capable of simultaneous passive imaging and dynamic ranging in different regions of the detector is presented. Such an adaptive-autonomous detector with both spatial and temporal control requires programmable window of exposure (time frames), ability to switch between readout modes such as full-frame imaging and zero-suppressed data, modification of the number of pixel data bits and independent programmability for distinct detector regions. In this work, a method is presented for seamlessly changing time frames and readout modes without data corruption while still ensuring that the data acquisition system (DAQ) does not need to stop and resynchronize at each change of setting, thus avoiding significant dead time. Data throughput is maximized by using a minimum unique data format, rather than lengthy frame headers, to differentiate between consecutive frames. A data control and transmitter (DCT) synchronizes data transfer from the pixel to the periphery, reconfigures the data to transmit it serially off-chip, while providing optimized decision support based on a DAQ definable mode. Measurements on a test structure demonstrate that the DCT can operate at 1 GHz in a 65 nm LP CMOS process.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗
DOE OSTI2024

A Modular 512-Channel Neural Signal Acquisition ASIC for High-Density 4096 Channel Electrophysiology

The complexity of information processing in the brain requires the development of technologies that can provide spatial and temporal resolution by means of dense electrode arrays paired with high-channel-count signal acquisition electronics. In this work, we present an ultra-low noise modular 512-channel neural recording circuit that is scalable to up to 4096 simultaneously recording channels. The neural readout application-specific integrated circuit (ASIC) uses a dense 8.2 mm × 6.8 mm 2D layout to enable high-channel count, creating an ultra-light 350 mg flexible module. The module can be deployed on headstages for small animals like rodents and songbirds, and it can be integrated with a variety of electrode arrays. The chip was fabricated in a TSMC 0.18 µm 1.8 V CMOS technology and dissipates a total of 125 mW. Each DC-coupled channel features a gain and bandwidth programmable analog front-end along with 14 b analog-to-digital conversion at speeds up to 30 kS/s. Additionally, each front-end includes programmable electrode plating and electrode impedance measurement capability. We present both standalone and in vivo measurements results, demonstrating the readout of spikes and field potentials that are modulated by a sensory input.

47 OTHER INSTRUMENTATION↗
DOE OSTI2025

The Linear Collider Facility (LCF) at CERN

In this paper we outline a proposal for a Linear Collider Facility as the next flagship project for CERN. It offers the opportunity for a timely, cost-effective and staged construction of a new collider that will be able to comprehensively map the Higgs boson's properties, including the Higgs field potential, thanks to a large span in centre-of-mass energies and polarised beams. A comprehensive programme to study the Higgs boson and its closest relatives with high precision requires data at centre-of-mass energies from the Z pole to at least 1 TeV. It should include measurements of the Higgs boson in both major production mechanisms, ee -> ZH and ee -> vvH, precision measurements of gauge boson interactions as well as of the W boson, Higgs boson and top-quark masses, measurement of the top-quark Yukawa coupling through ee ->ttH, measurement of the Higgs boson self-coupling through HH production, and precision measurements of the electroweak couplings of the top quark. In addition, ee collisions offer discovery potential for new particles complementary to HL-LHC.

43 PARTICLE ACCELERATORS↗
DOE OSTI2026

Quantum science with arrays of metastable helium-3 atoms

The motion of atoms in programmable optical tweezer arrays offers many new opportunities for neutral atom quantum science. These include inter- and intra-site atom motion for resource-efficient implementations of fermionic and bosonic modes, respectively, as well as tweezer transport for efficient compilation of arbitrary circuits. However, the exploitation of atomic motion for all three purposes and others is limited by the inertia of the atoms. We present a comprehensive architectural blueprint for the use of fermionic metastable helium-3 (He) atoms -- the lightest trappable atomic species -- in programmable optical tweezer arrays. This includes a concrete analysis of atomic structure considerations as well as Rydberg-mediated interactions. We show that inter-tweezer hopping of He atoms can be faster than previous demonstrations with lithium-6. We also demonstrate a new toolbox for encoding and manipulating qubits directly in the tweezer trap potential, uniquely enabled by the light mass of He. Finally, we provide several examples of new opportunities for fermionic quantum simulation and computation that leverage the transport and inter-tweezer hopping of He atom arrays. These tools present new methods to improve the resource efficiency of neutral atom quantum science that may also enable quantum simulations of lattice gauge theories and quantum chemistry outside the Born-Oppenheimer approximation

Li, Zheyuan↗
DOE OSTI2016

Russia's black carbon emissions: focus on diesel sources

Black carbon (BC) is a significant climate forcer with a particularly pronounced forcing effect in polar regions such as the Russian Arctic. Diesel combustion is a major global source of BC emissions, accounting for 25–30 % of all BC emissions. While the demand for diesel is growing in Russia, the country's diesel emissions are poorly understood. This paper presents a detailed inventory of Russian BC emissions from diesel sources. Drawing on a complete Russian vehicle registry with detailed information about vehicle types and emission standards, this paper analyzes BC emissions from diesel on-road vehicles. We use the COPERT emission model (COmputer Programme to calculate Emissions from Road Transport) with Russia-specific emission factors for all types of on-road vehicles. On-road diesel vehicles emitted 21 Gg of BC in 2014: heavy-duty trucks account for 60% of the on-road BC emissions, while cars represent only 5% (light commercial vehicles and buses account for the remainder). Using Russian activity data and fuel-based emission factors, the paper also presents BC emissions from diesel locomotives and ships, off-road engines in industry, construction and agriculture, and generators. The study also factors in the role of superemitters in BC emissions from diesel on-road vehicles and off-road sources. The total emissions from diesel sources in Russia are estimated to be 49 Gg of BC and 17 Gg of organic carbon (OC) in 2014. Off-road diesel sources emitted 58% of all diesel BC in Russia.

54 ENVIRONMENTAL SCIENCES↗
DOE OSTI2018

RNA-dependent RNA targeting by CRISPR-Cas9

Double-stranded DNA (dsDNA) binding and cleavage by Cas9 is a hallmark of type II CRISPR-Cas bacterial adaptive immunity. All known Cas9 enzymes are thought to recognize DNA exclusively as a natural substrate, providing protection against DNA phage and plasmids. Here, we show that Cas9 enzymes from both subtypes II-A and II-C can recognize and cleave single-stranded RNA (ssRNA) by an RNA-guided mechanism that is independent of a protospacer-adjacent motif (PAM) sequence in the target RNA. RNA-guided RNA cleavage is programmable and site-specific, and we find that this activity can be exploited to reduce infection by single-stranded RNA phage in vivo. We also demonstrate that Cas9 can direct PAM-independent repression of gene expression in bacteria. These results indicate that a subset of Cas9 enzymes have the ability to act on both DNA and RNA target sequences, and suggest the potential for use in programmable RNA targeting applications.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗
DOE OSTI2022

Molecular mechanism of active Cas7-11 in processing CRISPR RNA and interfering target RNA

Cas7-11 is a Type III-E CRISPR Cas effector that confers programmable RNA cleavage and has potential applications in RNA interference. Cas7-11 encodes a single polypeptide containing four Cas7- and one Cas11-like segments that obscures the distinction between the multi-subunit Class 1 and the single-subunit Class-2 CRISPR Cas systems. We report a cryo-EM (cryo-electron microscopy) structure of the active Cas7-11 from Desulfonema ishimotonii (DiCas7-11) that reveals the molecular basis for RNA processing and interference activities. DiCas7-11 arranges its Cas7- and Cas11-like domains in an extended form that resembles the backbone made up by four Cas7 and one Cas11 subunits in the multi-subunit enzymes. Unlike the multi-subunit enzymes, however, the backbone of DiCas7-11 contains evolutionarily different Cas7 and Cas11 domains, giving rise to their unique functionality. The first Cas7-like domain nearly engulfs the last 15 direct repeat nucleotides in processing and recognition of the CRISPR RNA, and its free-standing fragment retains most of the activity. Both the second and the third Cas7-like domains mediate target RNA cleavage in a metal-dependent manner. The structure and mutational data indicate that the long variable insertion to the fourth Cas7 domain has little impact on RNA processing or targeting, suggesting the possibility for engineering a compact and programmable RNA interference tool.

59 BASIC BIOLOGICAL SCIENCES↗
DOE OSTI2014

COMPOSE-HPC: Software Composition for Extreme Scale Computational Science and Engineering

Software composition is an important aspect of computational science software engineering due to large scale production science codes involving multiple programming languages, execution and concurrency models. To date, programmers must manage the complexity of building and maintaining such systems largely by hand with minimal (if any) automated assistance. As such, a great deal of programmer time is spent generating and maintaining code which leads to a high maintenance and development cost, as well as an increased risk of errors being introduced by hand than would be expected in an automated system. COMPOSE-HPC was a multi-institutional effort, with the Galois contribution focused on a specific area of code analysis and software infrastructure. Specifically, Galois led the design and implementation for the Parser for Annotations in a User-specified Language (PAUL), as well as collaborating with SNL and LLNL on the Retargetable Open Transformation Engine (ROTE). Both components were built on top of the ROSE compiler infrastructure from LLNL. All artifacts developed under the COMPOSE-HPC program are available on the github.com and sourceforge.net open source hosting sites under permissive BSD3 software licenses.

97 MATHEMATICS AND COMPUTING↗
DOE OSTI2014

Petaflops router

Disclosed is a method and system for performing operations on at least one input data vector in order to produce at least one output vector to permit easy, scalable and fast programming of a petascale equivalent supercomputer. A PetaFlops Router may comprise one or more PetaFlops Nodes, which may be connected to each other and/or external data provider/consumers via a programmable crossbar switch external to the PetaFlops Node. Each PetaFlops Node has a FPGA and a programmable intra-FPGA crossbar switch that permits input and output variables to be configurably connected to various physical operators contained in the FPGA as desired by a user. This allows a user to specify the instruction set of the system on a per-application basis. Further, the intra-FPGA crossbar switch permits the output of one operation to be delivered as an input to a second operation. By configuring the external crossbar switch, the output of a first operation on a first PetaFlops Node may be used as the input for a second operation on a second PetaFlops Node. An embodiment may provide an ability for the system to recognize and generate pipelined functions. Streaming operators may be connected together at run-time and appropriately staged to allow data to flow through a series of functions. This allows the system to provide high throughput and parallelism when possible. The PetaFlops Router may implement the user desired instructions by appropriately configuring the intra-FPGA crossbar switch on each PetaFlops Node and the external crossbar switch.

97 MATHEMATICS AND COMPUTING↗