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At least 613 records · Page 34

Spacelab Life Sciences flight experiments: an integrated approach to the study of cardiovascular deconditioning and orthostatic hypotension

The microgravity environment of spaceflight produces rapid cardiovascular changes which are adaptive and appropriate in that setting, but are associated with significant deconditioning and orthostatic hypotension on return to Earth's gravity. The rapidity with which these space flight induced changes appear and disappear provides an ideal model for studying the underlying pathophysiological mechanisms of deconditioning and orthostatic hypotension, regardless of etiology. Since significant deconditioning is seen after flights of very short duration, muscle atrophy due to inactivity plays, at most, a small role. These changes in circulatory control associated with cephalad fluid shifts, rather than inactivity per se, are probably more important factors. In order to test this hypothesis in a systematic way, a multidisciplinary approach which defines and integrates inputs and responses from a wide variety of circulatory sub-systems is required. The cardiovascular experiments selected for Spacelab Life Sciences flights 1 and 2 provide such an approach. Both human and animal models will be utilized. Pre- and post-flight characterization of the payload crew includes determination of maximal exercise capacity (bicycle ergometry), orthostatic tolerance (lower body negative pressure), alpha and beta adrenergic sensitivity (isoproterenol and phenylephrine infusions), baroreflex sensitivity (ECG-gated, stepwise changes in carotid artery transmural pressure with a pneumatic neck collar), and responses to a 24 h period of 5 deg head-down tilt. Measurements of cardiac output (CO2 and C2H2 rebreathing), cardiac chamber dimensions (phased-array 2-dimensional echocardiography), direct central venous pressure, leg volume (Thornton sock), limb blood flow and venous compliance (occlusion plethysmography), blood and plasma volumes, renal plasma flow and glomerular filtration rates, and various hormonal levels including catecholamines and atrial natriuretic factor will also be obtained. The central venous catheter will be inserted immediately pre-launch and monitored with heart rate and blood pressure in-flight until cardiac output, respiratory gas exchange and quantitative 2D echocardiography measurements can be performed. In-flight hemodynamic measurements will be repeated at rest and during submaximal exercise daily and also during maximal exercise midway through the flight to document the timecourse and extent of cardiovascular changes in the payload crew. Parallel studies are planned for the animals. In addition to measurements of right atrial and aortic pressures and cardiac output, a dorsal micro-circulatory chamber will allow determinations of changes in capillary and venular architecture and function in six of the rats. The techniques and findings from many of the SLS-1 and 2 supporting studies have already yielded significant information about circulatory regulation in patients with both hypo- and hypertension. The flight experiments themselves will provide new data to test the validity of both animal and human models currently used for simulating the fluid shifts of a micro-gravity environment. The development of effective countermeasures, not only for short and long duration space travellers, but also for Earth-bound medical patients can then be physiologically based on experimental data rather than anecdote.

Non-NASA Center↗

Galactic abundances as a relic neutrino detection scheme

We propose to use the threshold-free process of neutrino capture on β-decaying nuclei (NCB) with all available candidate nuclei in the Milky Way as target material in order to detect the presence of the Cosmic Neutrino Background (CνB). By integrating over the lifetime of the galaxy one might be able to see the effect of NCB processes as a slightly eschewed abundance ratio of selected β-decaying nuclei. First, the candidates must be chosen so that both the mother and daughter nuclei have a lifetime comparable to that of the Milky Way or the signal could be easily washed out by additional decays. Secondly, relic neutrinos have so low energy that their de Broglie wavelengths are macroscopic and they may therefore scatter coherently on the electronic cloud of the candidate atoms. One must therefore compare the cross sections for the two processes (induced β-decay by neutrino capture, and coherent scattering of the neutrinos on atomic nuclei) before drawing any conclusions. Finally, the density of target nuclei in the galaxy must be calculated. We assume supernovae as the only production source and approximate the neutrino density as a homogenous background. Here we perform the full calculation for {sup 187}Re and {sup 138}La and find that one needs abundance measurements with 24 digit precision in order to detect the effect of relic neutrinos. Or alternatively an enhancement of ρ{sub ν} by a factor of ∼ 10{sup 15} to produce an effect within the current abundance measurement precision.

79 ASTRONOMY AND ASTROPHYSICS↗

Light ion transfer reactions with the HELIOS spectrometer

Light-ion induced transfer and inelastic scattering reactions on stable or long-lived targets have been used extensively to study the structure of nuclei near the line of {beta}-stability, and much of the detailed information on the single-particle structure of nuclei has been derived from such studies. Recently, however, a substantial expansion of the range of isotopes, for which this nuclear structure information can be obtained, has presented itself by using radioactive beams in inverse kinematics reactions. Such beams are now available at a number of facilities around the world, including the in-flight production method and CARIBU facility at ATLAS. The HELIOS spectrometer, which has been used since August 2008 at ATLAS, circumvents many of the problems associated with inverse kinematics. In this talk I will discuss the principle of the spectrometer as well as some of main physics results that have been obtained to date in nuclei ranging from {sup 13}B to {sup 137}Xe using both stable and radioactive beams.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗

Revalidation of the isobaric multiplet mass equation for the A = 20 quintet

An unexpected breakdown of the isobaric multiplet mass equation in the A = 20, T = 2 quintet was recently reported, presenting a challenge to modern theories of nuclear structure. In the present work, the excitation energy of the lowest T = 2 state in Na-20 has been measured to be 6498.4 +/- 0.2 sta t ± 0.4 sys t keV by using the superallowed 0 + → 0 + beta decay of Mg-20 to access it and an array of high-purity germanium detectors to detect its gamma-ray deexcitation. This value differs by 27 keV (1.9 standard deviations) from the recommended value of 6525 ± 14 keV and is a factor of 28 more precise. The isobaric multiplet mass equation is shown to be revalidated when the new value is adopted.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗

Toward a neutrino-limited dark matter search with crystalline xenon

Experiments searching for weakly interacting massive particle dark matter are now detecting background events from solar neutrino-electron scattering. However, the dominant radioactive background in state-of-the-art experiments such as LZ and XENONnT is beta decays from radon contamination. In spite of careful detector material screening, radon progenitor atoms are ubiquitous and long-lived, and radon is extremely soluble in liquid xenon. We propose a change of phase and demonstrate that crystalline xenon offers more than a factor × 500 exclusion against radon ingress, compared with the liquid state. This level of radon exclusion would allow crystallized versions of existing experiments to probe spin-independent cross sections near 10 − 47 cm 2 in roughly 11 years, as opposed to the 35 years required otherwise. Published by the American Physical Society 2024

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Comparative Penicillium spp. Transcriptomics: Conserved Pathways and Processes Revealed in Ungerminated Conidia and during Postharvest Apple Fruit Decay

Blue mold, caused by Penicillium spp., is an impactful postharvest disease resulting in significant economic losses due to reduced pome fruit quality and mycotoxin contamination. Using two Penicillium species with different levels of aggressiveness, transcriptomics were implemented in order to identify genes expressed during apple fruit decay and loci expressed in ungerminated conidia. Total RNA was isolated from ungerminated conidia and decayed apple fruit infected with P. expansum R19 or P. polonicum RS1. There were 2442 differentially expressed genes (DEGs) between the R19 and RS1 in apple. Comparisons within species between apple and conidia revealed 4404 DEGs for R19 and 2935 for RS1, respectively. Gene ontology (GO) analysis revealed differential regulation in fungal transport and metabolism genes during decay, suggesting a flux in nutrient acquisition and detoxification strategies. In R19, the oxidoreductase GO category comprised 20% of all DEG groups in apple verses conidia. Ungerminated conidia from both species showed DEGs encoding the glyoxylate shunt and beta-oxidation, specifying the earliest metabolic requirements for germination. This is the first study to identify pre-loaded transcripts in conidia from blue mold fungi, reveal unique genes between species expressed during apple decay, and show the expression dynamics of known fungal virulence factors. These findings will enable development of targeted approaches for blue mold abatement strategies.

59 BASIC BIOLOGICAL SCIENCES↗

The interstellar carbon abundance. II - Rho Ophiuchi and Beta Scorpii

A procedure designed to obtain increased sensitivity from high-dispersion IUE spectra by using a flat-field spectrum to remove nonrandom noise due to the response pattern of the SEC vidicon detector is described. Application of this procedure to spectra of Rho Oph and Beta(1) Sco near the spin-forbidden interstellar 2325 line of C II yields 2 sigma upper limits on absorption of W (lambda) not greater than about 4 mA. The resulting depletion of carbon from the interstellar gas toward Rho Oph exceeds a factor of 1.4.

Welty, D. E.↗

Kinetics and Thermochemistry of the Br((sup 2)P3/2) + NO2 Association Reaction

A laser flash photolysis-resonance fluorescence technique has been employed to study the kinetics of the Br((sup 2)P3/2) + NO2 association reaction as a function of temperature (259-432 K) pressure (12.5 - 700 Torr), and buffer gas identity (He, Ar, H2, N2, CO2, CF4, SF6). The reaction is found to be in the falloff regime between third and second order over the entire range of conditions investigated. At temperatures below 350 K, the association reaction is found to be irreversible on the time scale of the experiment (approximately 30 ms). At higher temperatures reversible addition is observed, allowing equilibrium constants for BrNO2 formation and dissociation to be determined. Second- and third-law analyses of the equilibrium data are in only fair agreement and lead to the following thermochemical parameters for the association reaction: Delta-H(298) = 19.6 +/- 1.7 kcal/mol, Delta-H(0) = -18.6 +/- 2.0 kcal/mol, Delta-S(298) = 29.3 +/- 4.2 cal/mol/K, Delta-H(sub f)(sub 298)(BrNO2) = 17.0 +/-1.8 kcal/mol(uncertainties are 2 sigma estimates of absolute accuracy). The value for Delta-H(0) determined in this study has been employed to calculate k(sub 0)(sup SC), the low-pressure third-order rate coefficient in the strong collision limit, by using the method of Troe; calculated values of k(sub 0)(sup SC) are inconsistent with experimental results unless Delta-H(0) is assigned a value near the lower limit derived from analysis of the high-temperature approach to equilibrium data, i.e. delta-H(0) approximately equals -16.6 kcal/mol. A potential source of systematic error in the calculation of both k(sub 0)(sup SC) and the absolute entropy of BrNO2 results from the complete lack of knowledge of the energies and degeneracies of the electronic states of BrNO3. The procedure developed by Troe and co-workers has been employed to extrapolate experimental falloff curves to the low- and high-pressure limits. Derived values for k(sub 0)(M,298K) in units of 10(exp -31) cm(exp 6)/sq molecule/s range from 2.75 for M = He to 6.54 for M = CO2; 2 sigma uncertainties are estimated to be +/- 20%. Values for k(sub 0)(N2,T) in units of 10(exp -31) cm(exp 6)/sq molecule/s are 5.73 at 259 K, 4.61 at 298 K, and 3.21 at 346 K; the observed temperature dependence for k(sub 0)(N2,T) is consistent with the theoretical temperature dependence for Beta(sub c)k(sub 0)(sup SC). Values for k(sub infinity)(T) in units of 10(exp -11) cu cm/molecule/s are 2.86 at 259 K, 3.22 at 298 K, and 3.73 at 346 K; 2 sigma uncertainties are estimated to be a factor of 2. Approximate falloff parameters in a convenient format for atmospheric modeling are also derived.

Kreutter, K. D.↗

Advances in the Design of the SuperB Final Doublet

SuperB is an asymmetric energy e{sup +}e{sup -} collider operating at the {Upsilon}(4S) peak with a design peak luminosity of 10{sup 36} Hz/cm{sup 2} to be built in Italy in the very near future. The design luminosity is almost a factor hundred higher than that of the present generation comparable facilities. To get the design luminosity a novel collision scheme, the so called 'large Piwinski angle with crab waist', has been designed. The scheme requires a short focus final doublet to reduce the vertical beta function down to {beta}*{sub y} = 0.2mm at the interaction point (IP). The final doublet will be composed by a set of permanent and superconducting (SC) quadrupoles. The SC quadrupole doublets QD0/QF1 will be placed as close to the IP as possible. This layout is critical because the space available for the doublets is very small. An advanced design of the quadrupole has been developed, based on the so-called helical coil concept. The paper discusses the design concept, the construction and the results of test of a model of the superconducting quadrupole based on NbTi technology. Future developments are also presented.

43 PARTICLE ACCELERATORS↗

Summary of the Mechanical Performances of the 1.5 m Long Models of the Nb $_{3}$ Sn Low- $\beta$ Quadrupole MQXF

The Nb 3 Sn quadrupole MQXF is being developed as a part of the large hadron collide (LHC) High Luminosity upgrade. The magnet design was tested on 1.5-m-long short models, sharing the same cross section with the full-length magnets. Various azimuthal and longitudinal preloads were applied, studying the impact on the magnet training and on its mechanical performances. The experiments demonstrated the possibility to control the magnet prestress. However, various factors, coil size among the others, may affect the stress variation between and within each winding. This variation could prevent the magnets from reaching the magnet performances, as for example as a result of the critical current reduction of the Nb 3 Sn strands. This paper analyzes the mechanical performances of the short models, studying in particular the stress variation on different coils. The measured coil size was used as input in the numerical simulations, and the results were then compared with the strain gauge measurements. Lastly, the short model experience was used to evaluate the feasibility of a loading operation that does not rely on the strain measurements.

75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND↗

Hydrogen atom distribution and hydrogen induced site depopulation for the La{sub 2-x}Mg{sub x}Ni{sub 7}-H system

La{sub 2-x}Mg{sub x}Ni{sub 7} and its hydrides/deuterides were investigated by high resolution synchrotron powder X-ray and neutron diffraction. Upon deuteration the single phase sample of the intermetallic compound with the refined composition La{sub 1.63}Mg{sub 0.37}Ni{sub 7} (space group: P6{sub 3}/mmc) expands isotropically, in contrast to the Mg free phase. The hydrogen uptake, {approx}9 D/f.u., is higher than in La{sub 2}Ni{sub 7}D{sub 6.5}. The refined composition accounts for La{sub 1.63}Mg{sub 0.37}Ni{sub 7}D{sub 8.8} (beta-phase). Rietveld refinements using the neutron and synchrotron diffraction data suggest that deuterium atoms occupy 5 different interstitial sites within both AB{sub 2} and AB{sub 5} slabs, either in an ordered or a disordered way. All determined D sites have an occupancy >50% and the shortest D-D contact is 1.96(3) A. It is supposed that a competition between the tendency to form directional bonds and repulsive D-D (H-H) interactions is the most important factor that influences the distribution of deuterium atoms in this structure. A hitherto unknown second, alpha-phase with composition La{sub 1.63}Mg{sub 0.37}Ni{sub 7}D{sub 0.56}, crystallizing with the same hexagonal symmetry as La{sub 1.63}Mg{sub 0.37}Ni{sub 7}D{sub 8.8}, has been discovered. The unit cell parameters for this D-poor phase differ slightly from those of the intermetallic. Alpha-phase displays only one D site (4f, space group: P6{sub 3}/mmc) occupied >50%, which is not populated in the D-rich beta-phase. This hydrogen/deuterium induced site depopulation can be explained by repulsive D-D (H-H) interactions that are likely to influence non-occupancy of certain interstices in metal lattice when absorbing hydrogen. - Graphical abstract: The detailed D atoms arrangement in La{sub 1.63}Mg{sub 0.37}Ni{sub 7}D{sub 8.8} differs significantly from the previously reported La{sub 1.5}Mg{sub 0.5}Ni{sub 7}D{sub 8.9(9.1)}. The present model consists of only five deuterium sites as opposed to nine proposed for La{sub 1.5}Mg{sub 0.5}Ni{sub 7}D{sub 8.9(9.1)}. The reported four remaining deuterium atom positions in La{sub 1.5}Mg{sub 0.5}Ni{sub 7}D{sub 8.9(9.1)} were not found in the investigated La{sub 1.63}Mg{sub 0.37}Ni{sub 7}D{sub 8.8}. The five Ni atoms have deuterium among their nearest neighbors, which surround them in a way similar to configurations observed in some complex transition metal hydrides and already reported for metallic hydrides. In the presented deuterium-rich phase, deformed tetrahedron, rigid trigonal pyramids as well as disordered and deformed saddle-like configuration are observed. Highlights: Black-Right-Pointing-Pointer Alpha- and beta-phase for La{sub 2-x}Mg{sub x}Ni{sub 7}-H system have been characterized. Black-Right-Pointing-Pointer Five different interstitial sites are occupied by deuterium/hydrogen atoms in the beta-phase. Black-Right-Pointing-Pointer One D/H site has been determined in the alpha-phase. Black-Right-Pointing-Pointer Deuterium/hydrogen induced site depopulation during phase transformation is observed. Black-Right-Pointing-Pointer Ni atoms tend to have tetrahedral-like D/H atom coordination.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

A Novel Sparse Compositional Technique Reveals Microbial Perturbations

ABSTRACT The central aims of many host or environmental microbiome studies are to elucidate factors associated with microbial community compositions and to relate microbial features to outcomes. However, these aims are often complicated by difficulties stemming from high-dimensionality, non-normality, sparsity, and the compositional nature of microbiome data sets. A key tool in microbiome analysis is beta diversity, defined by the distances between microbial samples. Many different distance metrics have been proposed, all with varying discriminatory power on data with differing characteristics. Here, we propose a compositional beta diversity metric rooted in a centered log-ratio transformation and matrix completion called robust Aitchison PCA. We demonstrate the benefits of compositional transformations upstream of beta diversity calculations through simulations. Additionally, we demonstrate improved effect size, classification accuracy, and robustness to sequencing depth over the current methods on several decreased sample subsets of real microbiome data sets. Finally, we highlight the ability of this new beta diversity metric to retain the feature loadings linked to sample ordinations revealing salient intercommunity niche feature importance. IMPORTANCE By accounting for the sparse compositional nature of microbiome data sets, robust Aitchison PCA can yield high discriminatory power and salient feature ranking between microbial niches. The software to perform this analysis is available under an open-source license and can be obtained at https://github.com/biocore/DEICODE ; additionally, a QIIME 2 plugin is provided to perform this analysis at https://library.qiime2.org/plugins/q2-deicode .

59 BASIC BIOLOGICAL SCIENCES↗

Quantifying the Seasonal and Interannual Variability of North American Isoprene Emissions Using Satellite Observations of the Formaldehyde Column

Quantifying isoprene emissions using satellite observations of the formaldehyde (HCHO) columns is subject to errors involving the column retrieval and the assumed relationship between HCHO columns and isoprene emissions, taken here from the GEOS-CHEM chemical transport model. Here we use a 6-year (1996-2001) HCHO column data set from the Global Ozone Monitoring Experiment (GOME) satellite instrument to (1) quantify these errors, (2) evaluate GOME-derived isoprene emissions with in situ flux measurements and a process-based emission inventory (Model of Emissions of Gases and Aerosols from Nature, MEGAN), and (3) investigate the factors driving the seasonal and interannual variability of North American isoprene emissions. The error in the GOME HCHO column retrieval is estimated to be 40%. We use the Master Chemical Mechanism (MCM) to quantify the time-dependent HCHO production from isoprene, alpha- and beta-pinenes, and methylbutenol and show that only emissions of isoprene are detectable by GOME. The time-dependent HCHO yield from isoprene oxidation calculated by MCM is 20-30% larger than in GEOS-CHEM. GOME-derived isoprene fluxes track the observed seasonal variation of in situ measurements at a Michigan forest site with a -30% bias. The seasonal variation of North American isoprene emissions during 2001 inferred from GOME is similar to MEGAN, with GOME emissions typically 25% higher (lower) at the beginning (end) of the growing season. GOME and MEGAN both show a maximum over the southeastern United States, but they differ in the precise location. The observed interannual variability of this maximum is 20-30%, depending on month. The MEGAN isoprene emission dependence on surface air temperature explains 75% of the month-to-month variability in GOME-derived isoprene emissions over the southeastern United States during May-September 1996-2001.

Palmer, Paul I.↗

THE STAR FORMATION RATE OF TURBULENT MAGNETIZED CLOUDS: COMPARING THEORY, SIMULATIONS, AND OBSERVATIONS

The role of turbulence and magnetic fields is studied for star formation in molecular clouds. We derive and compare six theoretical models for the star formation rate (SFR)-the Krumholz and McKee (KM), Padoan and Nordlund (PN), and Hennebelle and Chabrier (HC) models, and three multi-freefall versions of these, suggested by HC-all based on integrals over the log-normal distribution of turbulent gas. We extend all theories to include magnetic fields and show that the SFR depends on four basic parameters: (1) virial parameter {alpha}{sub vir}; (2) sonic Mach number M; (3) turbulent forcing parameter b, which is a measure for the fraction of energy driven in compressive modes; and (4) plasma {beta}=2M{sub A}{sup 2}/M{sup 2} with the Alfven Mach number M{sub A}. We compare all six theories with MHD simulations, covering cloud masses of 300 to 4 Multiplication-Sign 10{sup 6} M{sub Sun} and Mach numbers M=3-50 and M{sub A}=1-{infinity}, with solenoidal (b = 1/3), mixed (b = 0.4), and compressive turbulent (b = 1) forcings. We find that the SFR increases by a factor of four between M=5 and 50 for compressive turbulent forcing and {alpha}{sub vir} {approx} 1. Comparing forcing parameters, we see that the SFR is more than 10 times higher with compressive than solenoidal forcing for M=10 simulations. The SFR and fragmentation are both reduced by a factor of two in strongly magnetized, trans-Alfvenic turbulence compared to hydrodynamic turbulence. All simulations are fit simultaneously by the multi-freefall KM and multi-freefall PN theories within a factor of two over two orders of magnitude in SFR. The simulated SFRs cover the range and correlation of SFR column density with gas column density observed in Galactic clouds, and agree well for star formation efficiencies SFE = 1%-10% and local efficiencies {epsilon} = 0.3-0.7 due to feedback. We conclude that the SFR is primarily controlled by interstellar turbulence, with a secondary effect coming from magnetic fields.

79 ASTRONOMY AND ASTROPHYSICS↗

A novel role for PTK2B in cultured beige adipocyte differentiation

Highlights: • PTK2B protein levels are higher during cultured beige versus white adipogenesis. • Ptk2b knock-out SVF cells have poor white adipocyte differentiation. • Ptk2b knock-out beige adipocytes have elevated lipid accumulation. • Ptk2b knock-out beige adipocytes have a greatly diminished thermogenic gene program. • Ptk2b knock-out beige adipocytes have altered mitochondrial respiration. Adipocyte differentiation is a tightly regulated process which requires the sequential and organized expression of numerous genes and proteins. Phosphorylation of cytoplasmic proteins and key transcription factors represents a critical regulatory mechanism of the process leading to adipocyte maturation and modulation of associated metabolic pathways. Despite the recognition of the importance of protein phosphorylation in adipocyte biology, relatively little is known about the role of specific kinases in thermogenic (brown or beige) adipocyte differentiation and function. In this study, we demonstrate that the non-receptor protein tyrosine kinase 2 beta (PTK2B) plays a critical role in murine beige adipocyte differentiation. We observed that PTK2B protein expression is associated with beige adipocyte differentiation in cultured, immortalized, inguinal stromal vascular fraction cells. CRISPR/Cas9-mediated knock-out of Ptk2b results in non-differentiating white adipocytes, and differentiated beige adipocytes with significantly reduced thermogenic gene and protein expression, enlarged lipid droplet size, and altered mitochondrial respiration. Together, our data in a cell culture system provides evidence for a role of PTK2B in the differentiation of murine beige adipocytes.

60 APPLIED LIFE SCIENCES↗

Kinetic Alfven wave instability driven by a field-aligned current in high-{beta} plasmas

Including the ion-gyroradius effect, a general low-frequency kinetic dispersion equation is presented, which simultaneously takes account of a field-aligned current and temperature anisotropy in plasmas. Based on this dispersion equation, kinetic Alfven wave (KAW) instability driven by the field-aligned current, which is carried by the field-aligned drift of electrons relative to ions at a drift velocity V{sub D}, is investigated in a high-{beta} plasma, where {beta} is the kinetic-to-magnetic pressure ratio in the plasma. The numerical results show that the KAW instability driven by the field-aligned current has a nonzero growth rate in the parallel wave-number range 0<k{sub z}<k{sub z}{sup u}, where the growth rate reaches a maximum at k{sub z}{approx}k{sub z}{sup u}/2. On the other hand, in the perpendicular wave-number range 0<k{sub perpendicular}<k{sub perpendicular}{sup u} the growth rate monotonously decreases with the wave number k{sub perpendicular} from a maximum at k{sub perpendicular}=0 to zero at k{sub perpendicular}=k{sub perpendicular}{sup u}. In particular, the upper boundaries of the growing ranges in the wave-number space, k{sub z}{sup u} and k{sub perpendicular}{sup u}, as well as the growth rate increase with V{sub D}, imply that there are wider growing ranges and larger growth rate for larger drift velocities. Including the temperature anisotropy of plasma particles, the result shows that the instability conditions for these two driven mechanisms are both modified considerably, in which the growing parametric ranges of KAWs widen. The results have potential importance in understanding the physics of space and astrophysical plasma active phenomena since the field-aligned current, also called the Birkeland current, is one of the most active factors in plasma phenomena.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

Thermodynamic and Structural Study of the Copper-Aluminum System by the Electrochemical Method Using a Copper-Selective Beta″ Alumina Membrane

The liquid phase thermodynamics of mixing of the copper-aluminum binary system are investigated as a function of temperature and composition using the electrochemical potential difference method. A copper-selective beta″ alumina is used as a solid electrolyte, synthesized through ion exchange, sintering from base oxide powders, and the floating zone method of crystal growth. Measured thermodynamics of mixing data were used to inform short-range ordering in copper-aluminum melts through Darken’s factor for excess stability and Bhatia–Thornton structure factors, revealing a strong departure from ideality and pronounced ordering. Mixing properties were used to predict viscosity and self-diffusion coefficients. Features observed in calculated electronic entropy of mixing for copper-aluminum were compared with trends in viscosity, demonstrating the utility of electronic properties of mixing in the description of structure–properties in this liquid binary system.

36 MATERIALS SCIENCE↗