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Results for “mathematics and computing”

Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 613 records · Page 34
All sourcesNASA NTRSDOE OSTI
NASA NTRS1976

A three-dimensional, time-dependent model of Mobile Bay

A three-dimensional, time-variant mathematical model for momentum and mass transport in estuaries was developed and its solution implemented on a digital computer. The mathematical model is based on state and conservation equations applied to turbulent flow of a two-component, incompressible fluid having a free surface. Thus, bouyancy effects caused by density differences between the fresh and salt water, inertia from thare river and tidal currents, and differences in hydrostatic head are taken into account. The conservation equations, which are partial differential equations, are solved numerically by an explicit, one-step finite difference scheme and the solutions displayed numerically and graphically. To test the validity of the model, a specific estuary for which scaled model and experimental field data are available, Mobile Bay, was simulated. Comparisons of velocity, salinity and water level data show that the model is valid and a viable means of simulating the hydrodynamics and mass transport in non-idealized estuaries.

Pitts, F. H.↗
NASA NTRS1998

Ensembles of radial basis function networks for spectroscopic detection of cervical precancer

The mortality related to cervical cancer can be substantially reduced through early detection and treatment. However, current detection techniques, such as Pap smear and colposcopy, fail to achieve a concurrently high sensitivity and specificity. In vivo fluorescence spectroscopy is a technique which quickly, noninvasively and quantitatively probes the biochemical and morphological changes that occur in precancerous tissue. A multivariate statistical algorithm was used to extract clinically useful information from tissue spectra acquired from 361 cervical sites from 95 patients at 337-, 380-, and 460-nm excitation wavelengths. The multivariate statistical analysis was also employed to reduce the number of fluorescence excitation-emission wavelength pairs required to discriminate healthy tissue samples from precancerous tissue samples. The use of connectionist methods such as multilayered perceptrons, radial basis function (RBF) networks, and ensembles of such networks was investigated. RBF ensemble algorithms based on fluorescence spectra potentially provide automated and near real-time implementation of precancer detection in the hands of nonexperts. The results are more reliable, direct, and accurate than those achieved by either human experts or multivariate statistical algorithms.

Cervix Neoplasms/pathology↗
NASA NTRS1972

Photogrammetric calibration of the NASA-Wallops Island image intensifier system

An image intensifier was designed for use as one of the primary tracking systems for the barium cloud experiment at Wallops Island. Two computer programs, a definitive stellar camara calibration program and a geodetic stellar camara orientation program, were originally developed at Wallops on a GE 625 computer. A mathematical procedure for determining the image intensifier distortions is outlined, and the implementation of the model in the Wallops computer programs is described. The analytical calibration of metric cameras is also discussed.

Harp, B. F.↗
NASA NTRS1966

New computer system simplifies programming of mathematical equations

Automatic Mathematical Translator /AMSTRAN/ permits scientists or engineers to enter mathematical equations in their natural mathematical format and to obtain an immediate graphical display of the solution. This automatic-programming, on-line, multiterminal computer system allows experienced programmers to solve nonroutine problems.

Reinfelds, J.↗
NASA NTRS2020

Multi-Agent Motion Planning using Deep Learning for Space Applications

State-of-the-art motion planners cannot scale to a large number of systems. Motion planning for multiple agents is an NP (non-deterministic polynomial-time) hard problem, so the computation time increases exponentially with each addition of agents. This computational demand is a major stumbling block to the motion planner's application to future NASA missions involving the swarm of space vehicles. We applied a deep neural network to transform computationally demanding mathematical motion planning problems into deep learning-based numerical problems. We showed optimal motion trajectories can be accurately replicated using deep learning-based numerical models in several 2D and 3D systems with multiple agents. The deep learning-based numerical model demonstrates superior computational efficiency with plans generated 1000 times faster than the mathematical model counterpart.

Madani, Ramtin↗
DOE OSTI2013

Computational model for autophagic vesicle dynamics in single cells

Macroautophagy (autophagy) is a cellular recycling program essential for homeostasis and survival during cytotoxic stress. This process, which has an emerging role in disease etiology and treatment, is executed in four stages through the coordinated action of more than 30 proteins. An effective strategy for studying complicated cellular processes, such as autophagy, involves the construction and analysis of mathematical or computational models. When developed and refined from experimental knowledge, these models can be used to interrogate signaling pathways, formulate novel hypotheses about systems, and make predictions about cell signaling changes induced by specific interventions. Here, we present the development of a computational model describing autophagic vesicle dynamics in a mammalian system. We used time-resolved, live-cell microscopy to measure the synthesis and turnover of autophagic vesicles in single cells. The stochastically simulated model was consistent with data acquired during conditions of both basal and chemically induced autophagy. The model was tested by genetic modulation of autophagic machinery and found to accurately predict vesicle dynamics observed experimentally. Furthermore, the model generated an unforeseen prediction about vesicle size that is consistent with both published findings and our experimental observations. Taken together, this model is accurate and useful and can serve as the foundation for future efforts aimed at quantitative characterization of autophagy.

59 BASIC BIOLOGICAL SCIENCES↗
DOE OSTI2012

Agni: Coupling Model Analysis Tools and High-Performance Subsurface Flow and Transport Simulators for Risk and Performance Assessments

Agni is open source /community /multi platform framework for model-based analyses (SA, UQ, PE, RA, DS). Agni can be applied independently from other Advanced Simulation Capability for Environmental Management (ASCEM) modules. Agni will be available as Mercurial repository (hg clone https://akuna.labworks.org/hg/Platform) including source code, manual, test and verification examples.

COMPUTER CODES↗