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At least 613 records · Page 34

Design and Conduct of a Windshear Detection Flight Experiment

A description of the design and conduct of a series of flight experiments which tested the performance of candidate windshear detection devices is presented. With prototype windshear sensors installed, a NASA Boeing 737 test aircraft conducted numerous low altitude penetrations of microburst windshear conditions. These tests were preceded by extensive preparations which included piloted simulations, determination of safe operating limits, and the development of unique flight test hardware, displays, and procedures. The test aircraft and more than 50 research and support personnel were deployed to Orlando, Florida, and Denver, Colorado, during June and July 1991 for field testing. Upon receiving a forecast of developing weather activity, the aircraft crew launched and proceeded to the storm location, guided by uplinked ground radar information and voice communications with ground weather personnel. The tests required constant monitoring of numerous factors including aircraft flight parameters, ground obstructions, windshear magnitude, lightning, escape routes, ATC coordination, storm cell development, and others. The flight tests were extremely successful, safely recording more than 25 low altitude microburst windshear and strong gust front approaches and penetrations, along with completing a full test matrix of additional requirements related to windshear sensor performance. Data quality from the tests was excellent and indicates strong potential for airborne remote sensors to accurately predict and warn the flight crew of hazardous windshear conditions with ample time for precautionary crew action.

Flight Testing↗

Crystallinity of Fe-Ni Sulfides in Carbonaceous Chondrites

The main long-term goal of this research is to understand the physical conditions in the early solar nebula through the detailed characterization of a key class of mineral present in all primitive materials: Fe-Ni sulfides [1&2]. Fe-Ni sulfides can take dozens of structures, depending on the temperature of formation, as well as other physico-chemical factors which are imperfectly understood. Add to this the additional varying factor of Ni content, and we have a potentially sensitive cosmothermometer [3]. Unfortunately, this tool requires exact knowledge of the crystal structure of each grain being considered, and there have been few (none?) studies of the detailed structures of sulfides in chondritic materials. We report here on coordinated compositional and crystallographic investigation of Fe-Ni sulfides in diverse carbonaceous chondrites, initially Acfer 094 (the most primitive CM2 [4]) Tagish Lake (a unique type C2 [5]), a C1 lithology in Kaidun [6], Bali (oxidized CV3 [7]), and Efremovka (reduced CV3 [7]).

Zolensky, Michael E.↗

Whole Blood Activation Results in Altered T Cell and Monocyte Cytokine Production Profiles by Flow Cytometry

An excellent monitor of the immune balance of peripheral circulating cells is to determine their cytokine production patterns in response to stimuli. Using flow cytometry, a positive identification of cytokine producing cells in a mixed culture may be achieved. Recently, the ability to assess cytokine production following a whole-blood activation culture has been described. In this study, whole blood activation was compared to traditional PBMC activation and the individual cytokine secretion patterns for both T cells, T cell subsets and monocytes was determined by flow cytometry. RESULTS: For T cell cytokine assessment (IFNg/IL-10 and IL-21/L-4) following PMA +ionomycin activation: (1) a Significantly greater percentages of T cells producing IFNgamma and IL-2 were observed following whole-blood culture and (2) altered T cell cytokine production kinetics were observed by varying whole blood culture times. Four-color analysiS was used to allow assessment of cytokine production by specific T cell subsets. It was found that IFNgamma production was significantly elevated in the CD3+/CD8+ T cell population as compared to the CD3+/CD8- population following five hours of whole blood activation. Conversely, IL-2 and IL-10 production were Significantly elevated in the CD3+/CD8- T cell population as compared to the CD3+/CD8+ population. Monocyte cytokine production was assessed in both culture systems following LPS activation for 24 hours. A three-color flow cytometric was used to assess two cytokines (IL-1a/IL-12 and TNFa/IL-10) in conjunction with CD14. Nearly all monocytes were stimulated to produce IL-1a, IL-12 and TNFa. equally well in both culture systems, however monocyte production of IL-10 was significantly elevated in whole blood culture as compared to PBMC culture. IL-12 producing monocytes appeared to be a distinct subpopulation of the IL-1a producing set, whereas IL-10 and TNFa producing monocytes were largely mutually exclusive. IL-10 and TNFa producing monocytes may represent distinct monocyte subsets with unique functions. CONCLUSIONS: Whole blood culture eliminates the need to purify cell populations prior to culture and may have Significant utility for the routine monitoring of the cytokine balances of the peripheral blood T cell and monocyte populations. In addition, there are distinct advantages to performing whole-blood (WB) activation as compared to PBMC activation. These advantages would include retaining all various cell-cell interactions as well as any soluble factors present in serum that influence cell activation. In this study, alterations in cytokine production are demonstrated between whole blood and PBMC activation. It is likely that whole blood activation more accurately represents the in-vivo immune balance than PBMC activation.

Crucian, Brian E.↗

BioSentinel: Mission Summary and Lessons Learned From the First Deep Space Biology CubeSat Mission

Launched on Artemis-1, BioSentinel carries a biology experiment into deep space for the first time in 50 years. A 6U CubeSat form factor was utilized for the spacecraft which included technologies newly developed or adapted for operations beyond Earth orbit. The spacecraft carries onboard budding yeast, Saccharomyces cerevisiae, as an analog to human cells to test the biological response to deep space radiation. This was the maiden deep-space voyage for many of the subsystems, and the first time to evaluate their performance in flight operation. Flying a CubeSat beyond LEO comes with unique challenges with respect to trajectory uncertainty and mission operations planning. The nominal plan was a lunar fly-by, followed by an insertion into Heliocentric orbit. However, some possible scenarios included lunar eclipses that could have severely impacted the power budget during that phase of the mission, while others could have resulted in a “Retrograde” hyperbola at swing-by resulting in the spacecraft traveling inward toward Earth or even towards a collision with the lunar surface. The commissioning phase of the mission was successful and completed a week ahead of schedule. It did not come without its exciting moments and challenges. First contact with the spacecraft uncovered that the vehicle was unexpectedly tumbling after deployment, a situation that needed to be corrected urgently. The mission operations team executed a contingency plan to stabilize the spacecraft, with just moments to spare before the battery ran out of power. The BioSensor payload onboard the spacecraft is a complex instrument that includes microfluidics, fluid systems, sensor control electronics, as well at the living yeast cells. BioSentinel also included a TimePix radiation sensor implemented by JSC’s RadWorks group. Dose and Linear Energy Transfer (LET) data is compared directly to the rate of DSB-and repair events measured by the S. cerevisiae cells. BioSentinel mature nanosatellite technologies included: deep space communications and navigation, autonomous attitude control and momentum management, and micro-propulsion systems, to provide an adaptable nanosatellite platform for deep space uses. This paper discusses the performance of the BioSentinel spacecraft through the mission phase, and includes lessons learned from challenges and anomalies. BioSentinel had many successes and will be a pathfinder for future deep space CubeSats and biology missions.

BioSentinel↗

Biosentinel: Mission Summary and Lessons Learned From the First Deep Space Biology CubeSat Mission

Launched on Artemis-1, BioSentinel carries a biology experiment into deep space for the first time in 50 years. A 6U CubeSat form factor was utilized for the spacecraft which included technologies newly developed or adapted for operations beyond Earth orbit. The spacecraft carries onboard budding yeast, Saccharomyces cerevisiae, as an analog to human cells to test the biological response to deep space radiation. This was the maiden deep-space voyage for many of the subsystems, and the first time to evaluate their performance in flight operation. Flying a CubeSat beyond LEO comes with unique challenges with respect to trajectory uncertainty and mission operations planning. The nominal plan was a lunar fly-by, followed by an insertion into Heliocentric orbit. However, some possible scenarios included lunar eclipses that could have severely impacted the power budget during that phase of the mission, while others could have resulted in a “Retrograde” hyperbola at swing-by resulting in the spacecraft traveling inward toward Earth or even towards a collision with the lunar surface. The commissioning phase of the mission was successful and completed a week ahead of schedule. It did not come without its exciting moments and challenges. First contact with the spacecraft uncovered that the vehicle was unexpectedly tumbling after deployment, a situation that needed to be corrected urgently. The mission operations team executed a contingency plan to stabilize the spacecraft, with just moments to spare before the battery ran out of power. The BioSensor payload onboard the spacecraft is a complex instrument that includes microfluidics, fluid systems, sensor control electronics, as well at the living yeast cells. BioSentinel also included a TimePix radiation sensor implemented by JSC’s RadWorks group. Dose and Linear Energy Transfer (LET) data is compared directly to the rate of DSB-and repair events measured by the S. cerevisiae cells. BioSentinel mature nanosatellite technologies included: deep space communications and navigation, autonomous attitude control and momentum management, and micro-propulsion systems, to provide an adaptable nanosatellite platform for deep space uses. This paper discusses the performance of the BioSentinel spacecraft through the mission phase, and includes lessons learned from challenges and anomalies. BioSentinel had many successes and will be a pathfinder for future deep space CubeSats and biology missions.

BioSentinel↗

Biosentinel: The First Deep Space Biology CubeSat Mission- Mission Summary and Lessons Learned

Launched on Artemis-1, BioSentinel carries a biology experiment into deep space for the first time in 50 years. A 6U CubeSat form factor was utilized for the spacecraft which included technologies newly developed or adapted for operations beyond Earth orbit. The spacecraft carries onboard budding yeast, Saccharomyces cerevisiae, as an analog to human cells to test the biological response to deep space radiation. This was the maiden deep-space voyage for many of the subsystems, and the first time to evaluate their performance in flight operation. Flying a CubeSat beyond LEO comes with unique challenges with respect to trajectory uncertainty and mission operations planning. The nominal plan was a lunar fly-by, followed by an insertion into Heliocentric orbit. However, some possible scenarios included lunar eclipses that could have severely impacted the power budget during that phase of the mission, while others could have resulted in a “Retrograde” hyperbola at swing-by resulting in the spacecraft traveling inward toward Earth or even towards a collision with the lunar surface. The commissioning phase of the mission was successful and completed a week ahead of schedule. It did not come without its exciting moments and challenges. First contact with the spacecraft uncovered that the vehicle was unexpectedly tumbling after deployment, a situation that needed to be corrected urgently. The mission operations team executed a contingency plan to stabilize the spacecraft, with just moments to spare before the battery ran out of power. The BioSensor payload onboard the spacecraft is a complex instrument that includes microfluidics, fluid systems, sensor control electronics, as well at the living yeast cells. BioSentinel also included a TimePix radiation sensor implemented by JSC’s RadWorks group. Dose and Linear Energy Transfer (LET) data is compared directly to the rate of DSB-and repair events measured by the S. cerevisiae cells. BioSentinel mature nanosatellite technologies included: deep space communications and navigation, autonomous attitude control and momentum management, and micro-propulsion systems, to provide an adaptable nanosatellite platform for deep space uses. This paper discusses the performance of the BioSentinel spacecraft through the mission phase, and includes lessons learned from challenges and anomalies. BioSentinel had many successes and will be a pathfinder for future deep space CubeSats and biology missions.

BioSentinel↗

Access to Space for NASA Small Sats: Current and Future Needs

Small spacecraft technology advancements have fundamentally shifted how NASA’s Science Mission Directorate (SMD) executes science investigations. To support this approach, the SMD Rideshare Office (SRO) was established in 2020 to lead the definition and implementation of a directorate-wide rideshare strategy. Serving as the central point of contact for coordinating compatible NASA payloads with launch opportunities, the SRO maximizes science, exploration, and technology return on investment by enabling rideshare or other access to space opportunities for small spacecraft on SMD primary mission launches, VADR commercial launch procurements, and other government agency launch opportunities. As NASA seeks to reduce costs and increase the rate of discovery, small satellites and multi manifest access to space have become integral to achieving the agency’s strategic vision. While NASA has created the above-mentioned mechanisms to expand access to space and achieve lower launch costs for its small satellites, many factors have limited full exploit of the opportunity these mechanisms can bring. NASA continues to evolve its mission cultures and technical requirements to adapt and take advantage of burgeoning commercial launch and rideshare advancements. To do so NASA requires collaboration with small satellite manufacturers, principal investigators, and commercial industry partners. Current needs include technical development and design of structurally robust spacecraft buses capable of withstanding varied launch loads, which will increase rideshare interchangeability and versatility. Further, instrument and spacecraft designs must also evolve to handle diverse launch environments and loads factors, while reducing reliance on complex purge and cleanliness constraints, sensitivities to silicones and hydrocarbons, and magnetic requirements. Continued maturation of small and medium launch providers in the near-term is also essential to drive down costs through competition. The current mission selection cadence often complicates the ability to synchronize multiple missions on a single launch. Future needs can include affordable space maneuverability options such as enhanced spacecraft propulsion systems and unique orbital maneuvering capabilities for our individual smallsats or constellations. These emerging capabilities offer a path to unique science orbits for NASA small satellites, but only under the condition that their cost remains affordable and competitive to accommodate inherently smaller mission budgets. Additionally, the projected surge of multiple SMD small satellites launching simultaneously and to unique deep space science orbits necessitates evaluation of expanding deep space communications capabilities. This presentation provides a comprehensive overview of NASA SMD’s access to space landscape and offers further unique insights and discussion, backed by NASA rideshare experiences and lessons learned, on the current and future developments required to unleash the full potential of rideshare opportunities.

Rideshare↗

Access to Space for NASA SmallSats: Current and Future Needs

Small spacecraft technology advancements have fundamentally shifted how NASA’s Science Mission Directorate (SMD) executes science investigations. To support this approach, the SMD Rideshare Office (SRO) was established in 2020 to lead the definition and implementation of a directorate-wide rideshare strategy. Serving as the central point of contact for coordinating compatible NASA payloads with launch opportunities, the SRO maximizes science, exploration, and technology return on investment by enabling rideshare or other access to space opportunities for small spacecraft on SMD primary mission launches, VADR commercial launch procurements, and other government agency launch opportunities. As NASA seeks to reduce costs and increase the rate of discovery, small satellites and multi manifest access to space have become integral to achieving the agency’s strategic vision. While NASA has created the above-mentioned mechanisms to expand access to space and achieve lower launch costs for its small satellites, many factors have limited full exploit of the opportunity these mechanisms can bring. NASA continues to evolve its mission cultures and technical requirements to adapt and take advantage of burgeoning commercial launch and rideshare advancements. To do so NASA requires collaboration with small satellite manufacturers, principal investigators, and commercial industry partners. Current needs include technical development and design of structurally robust spacecraft buses capable of withstanding varied launch loads, which will increase rideshare interchangeability and versatility. Further, instrument and spacecraft designs must also evolve to handle diverse launch environments and loads factors, while reducing reliance on complex purge and cleanliness constraints, sensitivities to silicones and hydrocarbons, and magnetic requirements. Continued maturation of small and medium launch providers in the near-term is also essential to drive down costs through competition. The current mission selection cadence often complicates the ability to synchronize multiple missions on a single launch. Future needs can include affordable space maneuverability options such as enhanced spacecraft propulsion systems and unique orbital maneuvering capabilities for our individual smallsats or constellations. These emerging capabilities offer a path to unique science orbits for NASA small satellites, but only under the condition that their cost remains affordable and competitive to accommodate inherently smaller mission budgets. Additionally, the projected surge of multiple SMD small satellites launching simultaneously and to unique deep space science orbits necessitates evaluation of expanding deep space communications capabilities. This presentation provides a comprehensive overview of NASA SMD’s access to space landscape and offers further unique insights and discussion, backed by NASA rideshare experiences and lessons learned, on the current and future developments required to unleash the full potential of rideshare opportunities.

Rideshare↗

Interpretation of Lidar and Satellite Data Sets Using a Global Photochemical Model

A primary goal of the NASA Tropospheric Chemistry Program (TCP) is to "contribute substantially to scientific understanding of human impacts on the global troposphere". In order to analyze global or regional trends and factors of the troposphere chemistry, for example, its oxidation capacity or composition, a continuous global/regional data coverage as well as model simulations are needed. The Global Tropospheric Experiment (GTE), a major component of the TCP, provides data vital to these questions via aircraft measurement of key trace chemical species in various remote regions of the world. Another component in NASA's effort are satellite projects for exploration of tropospheric chemistry and dynamics. A unique data product is the Tropospheric Ozone Residual (TOR) utilizing global tropospheric ozone data. Another key research tool are simulation studies of atmospheric chemistry and dynamics for the theoretical understanding of the atmosphere, the extrapolation of observed trends, and for sensitivity studies assessing a changing anthropogenic impact to air chemistry and climate. In the context with model simulations, field data derived from satellites or (airborne) field missions are needed for two purposes: 1. To initialize and validate model simulations, and 2., to interpret field data by comparison to model simulation results in order to analyze global or regional trends and deviations from standard tropospheric chemistry and transport conditions as defined by the simulations. Currently, there is neither a sufficient global data coverage available nor are existing well established global circulation models. The NASA LARC CTM model is currently not yet in a state to accomplish a sufficient tropospheric chemistry simulation, so that the current research under this cooperative agreement focuses on utilizing field data products for direct interpretation. They will be also available for model testing and a later interpretation with a finally utilized model.

Zenker, Thomas↗

Absolute Navigation Performance of the Orion Exploration Fight Test 1

Launched in December 2014 atop a Delta IV Heavy from the Kennedy Space Center, the Orion vehicle's Exploration Flight Test-1 (EFT-1) successfully completed the objective to stress the system by placing the un-crewed vehicle on a high-energy parabolic trajectory replicating conditions similar to those that would be experienced when returning from an asteroid or a lunar mission. Unique challenges associated with designing the navigation system for EFT-1 are presented with an emphasis on how redundancy and robustness influenced the architecture. Two Inertial Measurement Units (IMUs), one GPS receiver and three barometric altimeters (BALTs) comprise the navigation sensor suite. The sensor data is multiplexed using conventional integration techniques and the state estimate is refined by the GPS pseudorange and deltarange measurements in an Extended Kalman Filter (EKF) that employs UDU factorization. The performance of the navigation system during flight is presented to substantiate the design.

Zanetti, Renato↗

Structural Certification of Human-Rated Inflatable Space Structures

This paper details the results of an initial study to develop a certification plan for human-rated inflatable space structures, including guidelines for qualification testing. Habitable softgoods inflatables are multi-layered shell structures that use high-strength webbing, cordage and broadcloth fabric to carry the skin loads of a variety of volumetric shapes and structural architectures. The primary objectives of this study are to define the key parameters that affect these structures and propose a statistically robust approach to defining safety and knockdown factors based on test and analysis. Current NASA standards for habitable inflatable space structures use a factor of safety of 4, which was inherited from airship design criteria. An updated approach to defining a design factor, taking into account material strength variability, load variability in the article, number of test samples, and damage and degradation effects is specified. Accurate analytical modeling of these structures is hindered by the difficulty of obtaining accurate and consistent material data due to load-history- dependent, nonlinear load versus strain behavior. A building block approach to certification is detailed that uses stochastic modeling and statistical test design and analysis to address the unique challenges these high-strength softgoods structures present. Human-rated inflatable modules are a transformative capability for launching much larger habitable volumes into space than is possible with rigid shell structures. This research aims to provide the framework for certifying these structures for future human space exploration missions.

Jones, Thomas C.↗

Understanding Climate-Vegetation Interactions in Global Rainforests Through a GP-Tree Analysis

The tropical rainforests are the largest reserves of terrestrial carbon and, therefore, the future of these rainforests is a question that is of immense importance in the geoscience research community. With the recent severe Amazonian droughts in 2005 and 2010 and on-going drought in the Congo region for more than two decades, there is growing concern that these forests could succumb to precipitation reduction, causing extensive carbon release and feedback to the carbon cycle. However, there is no single ecosystem model that quantifies the relationship between vegetation health in these rainforests and climatic factors. Small scale studies have used statistical correlation measure and simple linear regression to model climate-vegetation interactions, but suffer from the lack of comprehensive data representation as well as simplistic assumptions about dependency of the target on the covariates. In this paper we use genetic programming (GP) based symbolic regression for discovering equations that govern the vegetation climate dynamics in the rainforests. Expecting micro-regions within the rainforests to have unique characteristics compared to the overall general characteristics, we use a modified regression-tree based hierarchical partitioning of the space to build individual models for each partition. The discovery of these equations reveal very interesting characteristics about the Amazon and the Congo rainforests. Our method GP-tree shows that the rainforests exhibit tremendous resiliency in the face of extreme climatic events by adapting to changing conditions.

genetic programming↗

Global Positioning System Constellation Modernization Impact on Sidelobe Capable GPS Receivers in Geostationary Orbit

This paper provides on-orbit insight into Global Positioning System Receiver (GPSR) performance at a geostationary orbit (GEO) and contrasts that performance regarding the modernized and heritage GPS constellation currently operational. The subject matter of this paper falls under the following topics a) heritage and modern GPS transmit pattern comparison, b) GOES-R GPSR acquisition and tracking characterization regarding the first four operational GPS III vehicles, and c)relevant signal requirements as it pertains to GEO GPSR facilitation. The GPSR described herein is onboard the GOES-R series satellites. GOES-R (Geostationary Operational Environmental Satellite-R Series) is the first in a 4-part series of new weather satellites set to replace and upgrade the older GOES constellation. Two GOES-R have been launched to date, GOES-16 and GOES-17, the data presented in this paper are from both vehicles over common time spans. The GPSR on board this geostationary weather satellite is a mission critical, enabling technology which has been both tested on the ground and evaluated on-orbit to verify its effectivity[1]. This is a completely new system design consisting of a unique L1 GEO antenna, low-noise amplifier (LNA) assembly and a 12-channel GPSR capable of tracking the edge of the main beam and the sidelobes of the GPS L1 signal. Any satellite intending to maximize GPS navigation performance at GEO will need to implement a GPSR system that tracks sidelobes. GOES-R is the first civilian operational satellite to utilize GPS sidelobes for navigation at GEO, which is the key factor in the systems highly accurate, robust and continuous navigation solution. However, this also renders a distinct sensitivity to changes in the GPS transmit signal pattern in the sidelobe regime as a result of the new GPS III constellation modernization. This paper presents results showing that the GOES-RGPSR solution, given GPS constellation modernization to GPS III, although impacted slightly in received C/N0 at certain geometries, will continue to meet all performance requirements tracking up to 12 satellites and achieving excellent carrier-to-noise spectral density (C/N0).

GPS↗

Formulation of an effective safety design review for the Skylab Program.

The Skylab Program is presenting a unique set of requirements by extending the capabilities of both men and equipment to withstand extended periods of time in space. The progression of space programs which preceded Skylab have provided a set of building blocks of knowledge and experience coupled with an extensive ground test program which makes it possible to plan its flight program without earlier, unmanned test flights. This approach, however, makes it mandatory that to the maximum extent possible, we factor into the design review process all the 'lessons learned' which are applicable. It is this conscious review of the Skylab design, based on checklists prepared from design criteria, gleaned from a variety of sources and experiences, which is the subject of this paper. A brief description of the Skylab Program, its objectives, and the missions planned for it are presented briefly to better understand the degree of extrapolation of hardware development from previous programs.

Cohen, H.↗

Psychophysiology in microgravity and the role of exercise

The Space Transportation-Shuttle (STS) Program has greatly expanded our capabilities in space by allowing for missions to be flown more frequently, less expensively, and to encompass a greater range of goals than ever before. However, the scope of the United State's role and involvement in space is currently at the edge of a new and exciting era. The National Aeronautics and Space Administration (NASA) has plans for placing an orbiting space station (Space Station Freedom) into operation before the year 2000. Space Station Freedom promises to redefine the extent of our involvement in space even further than the STS program. Space Station crewmembers will be expected to spend extended periods of time (approximately 30 to 180 days) in space exposed to an extremely diverse and adverse environment (e.g., the major adversity being the chronic microgravity condition). Consequently, the detrimental effects of exposure to the microgravity environment is of primary importance to the biomedical community responsible for the health and well-being of the crewmembers. Space flight and microgravity exposure present a unique set of stressors for the crewmember; weightlessness, danger, isolation/confinement, irregular work-rest cycles, separation from family/friends, and mission/ground crew interrelationships. A great deal is beginning to be known about the physiological changes associated with microgravity exposure, however, limited objective psychological findings exist. Examination of this latter area will become of critical concern as NASA prepares to place crewmembers on the longer space missions that will be required on Space Station Freedom. Psychological factors, such as interpersonal relations will become increasingly important issues, especially as crews become more heterogeneous in the way of experience, professional background, and assigned duties. In an attempt to minimize the detrimental physiological effects of prolonged space flight and microgravity exposure, the United States and Russian space agencies have taken steps to implement various countermeasure programs. One of the principle countermeasures used by both nations is exercise during space flight. The purpose is to present a brief overview of the major research findings examining the psychophysiological changes associated with microgravity exposure, and to address the potential role of exercise as a countermeasure in affecting these psychophysiological changes.

Shaw, J. M.↗

The human role in space. Volume 3: Generalizations on human roles in space

The human role in space was studied. The role and the degree of direct involvement of humans that will be required in future space missions, was investigated. Valid criteria for allocating functional activities between humans and machines were established. The technology requirements, ecnomics, and benefits of the human presence in space were examined. Factors which affect crew productivity include: internal architecture; crew support; crew activities; LVA systems; IVA/EVA interfaces; and remote systems management. The accomplished work is reported and the data and analyses from which the study results are derived are included. The results provide information and guidelines to enable NASA program managers and decision makers to establish, early in the design process, the most cost effective design approach for future space programs, through the optimal application of unique human skills and capabilities in space.

Source record↗

Alternative Techniques for Testing A Highway Information Systems

The highway transport system as contrasted with other modes of transportation is quite unique in that the users of the system are responsible for the guidance and control functions of the vehicle. Research has shown that improved forms of motorist information, such as highway signs and markings, can enhance the predictability and reliability of the driving task. Test and evaluation of promising new concepts in motorist information must preceed widespread endorsement and implementation on our highway system. This paper reviews the merits and limitations of presently available human factor research techniques--laboratory, instrumented vehicle and traffic performance studies on operational facilities--for evaluating the efficacy of motorist information concepts. Specific examples are given to demonstrate the utility and the interrelationships of the alternative research techniques and there is a discussion of the most pressing immediate and future needs for improved highway signing and road marking research methodology.

Mast, Truman↗

Paternal Imprinting of Dosage-Effect Defective1 (Ded1) Contributes to Seed Weight Xenia in Maize

Historically, xenia effects were hypothesized to be unique genetic contributions of pollen to seed phenotype, but most examples represent standard complementation of Mendelian traits. We identified the imprinted dosage-effect defective1 (ded1) locus in maize (Zea mays) as a paternal regulator of seed size and development. Hypomorphic alleles show a 5-10% seed weight reduction when ded1 is transmitted through the male, while homozygous mutants are defective with a 70-90% seed weight reduction. Ded1 encodes an R2R3-MYB transcription factor expressed specifically during early endosperm development with paternal allele bias. DED1 directly activates early endosperm genes and endosperm adjacent to scutellum cell layer genes, while directly repressing late grain-fill genes. These results demonstrate xenia as originally defined: Imprinting of Ded1 causes the paternal allele to set the pace of endosperm development thereby influencing grain set and size.

Genomics↗