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NASA Space Flight Program and Project Management Handbook

This handbook is the companion document to NPR 7120.5F, NASA Space Flight Program and Project Management Requirements. It represents the accumulation of knowledge on managing program and projects derived from NASA’s human, robotic, and scientific missions. It incorporates the “corporate knowledge” for existing and future NASA space flight programs and projects, including NASA’s Artemis missions to establish a sustainable human presence on the Moon through collaboration with commercial and international partners, NASA’s James Webb Space Telescope (JWST) mission, and NASA’s robotic missions on Mars. The practices discussed have evolved as a function of NASA’s core values of safety, integrity, teamwork, excellence, and inclusion, and may also prove a resource for other agencies, the private sector, and academia. The knowledge gained from the Agency’s victories and defeats, including the checks and balances and initiatives to better control cost and risk, provides a foundation for continuing an exciting and healthy space program. This handbook provides implementation guidance for NPR 7120.5F and includes the changes and updates to key procedural requirements in NPR 7120.5F since NPR 7120.5E. The goal of the NPR requirements is to ensure programs and projects are developed and successfully executed in the most cost-effective and efficient manner possible. This handbook provides context, rationale, and explanation to facilitate the application of requirements and to pass on some of the hard-won best practices and lessons learned.

Tracy L Osborne↗

The Doppler Wind Temperature Sensor (DWTS) Flight Evaluation and Experiments (TES-16,17)

The Doppler Wind Temperature Sensor instrument (DWTS), developed by Global Atmospheric Technologies and Sciences (GATS), is a powerful yet simple tool with the potential of becoming a new window to upper atmosphere dynamics. Based around a defense-grade infrared camera peering through a static gas cell used as a scanning spectral filter, the DWTS is designed to measure the fingerprints of wind and thermal waves as they propagate to the mesosphere and lower thermosphere. DWTS achieves this scanning by measuring the induced change in the doppler shift of the emission as it passes through the DWTS field of view. DWTS holds promise to aid in more accurate weather determination (Gordley, et al), and the core technology can be easily adapted to study other atmospheres of interest. In partnership with GATS, NOAA, and other collaborators, NASA Ames and the Nano Orbital Workshop group have been working to evaluate the DWTS instrument on orbit and optimize it as a flexible cube satellite payload. The first mission selected for DWTS evaluation is preparing for flight in early 2024, followed by a more capable science mission in 2025, with both missions part of the TES-n/NOW flight series. The first flight, TES-16/DWTS-A, will incorporate a single DWTS instrument in an approximately 2U payload volume with the imaging aperture perpendicular to the flight velocity vector. With an estimated power consumption of 20 watts, supplied via a custom NOW-designed GaN converter, the instrument will maintain the imaging sensor plane at 80K using an integrated pulse-tube cryocooler during instrument evaluation periods. Data from DWTS will be captured via a NOW-designed custom data processor before being transmitted via S-band radio back to select ground stations, with instrument command and control operated via L-band global-coverage radio. After the TES-16/DWTS-A initial demonstration mission, the subsequent TES-17/DWTS-B mission will be a dedicated science mission equipped with three DWTS instruments, each hosting a different gas cell to obtain full altitude coverage from 20 to 200 km both day and night from a single cube satellite. The intention of the flight series, and one of NASA’s interests in the instrument, is to advance a Martian atmospheric instrument (Colaprete, Gordley, et al) which, if successful, would greatly further understanding of Martian atmospheric behavior. The proposed paper will review the flight series in detail, including challenges from the TES-16 flight tests and the projected challenges and application to Mars study. Additional detail regarding the possible applications of a Cognitive Communication technique in current flight development by NOW collaborators at the NASA Glenn Research Center will also be discussed, including the implications of using an automated User Initiated Service (UIS) protocol to maximize the data collected per orbit.

Doppler Wind Temperature Sensor↗

Eigensystem realization algorithm modal identification experiences with mini-mast

This paper summarizes work performed under a collaborative research effort between the National Aeronautics and Space Administration (NASA) and the German Aerospace Research Establishment (DLR, Deutsche Forschungsanstalt fur Luft- und Raumfahrt). The objective is to develop and demonstrate system identification technology for future large space structures. Recent experiences using the Eigensystem Realization Algorithm (ERA), for modal identification of Mini-Mast, are reported. Mini-Mast is a 20 m long deployable space truss used for structural dynamics and active vibration-control research at the Langley Research Center. A comprehensive analysis of 306 frequency response functions (3 excitation forces and 102 displacement responses) was performed. Emphasis is placed on two topics of current research: (1) gaining an improved understanding of ERA performance characteristics (theory vs. practice); and (2) developing reliable techniques to improve identification results for complex experimental data. Because of nonlinearities and numerous local modes, modal identification of Mini-Mast proved to be surprisingly difficult. Methods were available, ERA, for obtaining detailed, high-confidence results.

Pappa, Richard S.↗

Steps Toward a Large Space-Based UV/Optical Fizeau Interferometer: The GSFC Fizeau Interferometer Testbed (FIT)

Goddard Space Flight Center is pursuing the development of space-based, long-baseline (0.5km) UV-optical Fizeau imaging interferometers to enable the next major stride toward very high angular resolution astronomical observations. This effort includes the development and operation of the Fizeau Interferometry Testbed (FIT), in collaboration with the Naval Research Lab/NPOI, Univ. of MD, and Sigma Space Corporation. The FIT will be used to explore the principles of and requirements for the Stellar Imager (SI) mission concept (http://hires.gsfc.nasa.gov/~si) and other such Fizeau Interferometers/Sparse Aperture Telescope missions, leading in the end to the Planet Imager (PI), which is the ultimate goal of the current Origins Program. The primary goal of the FIT program is to demonstrate closed-loop control of mirrors (tip, tilt, piston, translation of array elements) and the overall system to keep the optical beams in phase and enable high quality imaging by a many-element (7-30) Fizeau Interferometric System. The FIT will also be used to assess various wave-front reconstruction and sensing and image reconstruction algorithms for utility and accuracy by application to real data generated by the Testbed. In this paper, we describe the design and goals of the system, provide a status report on its construction, and note our future plans.

Carpenter, K. G.↗

Airport Remote Tower Sensor Systems

Networks of video cameras, meteorological sensors, and ancillary electronic equipment are under development in collaboration among NASA Ames Research Center, the Federal Aviation Administration (FAA), and the National Oceanic Atmospheric Administration (NOAA). These networks are to be established at and near airports to provide real-time information on local weather conditions that affect aircraft approaches and landings. The prototype network is an airport-approach-zone camera system (AAZCS), which has been deployed at San Francisco International Airport (SFO) and San Carlos Airport (SQL). The AAZCS includes remotely controlled color video cameras located on top of SFO and SQL air-traffic control towers. The cameras are controlled by the NOAA Center Weather Service Unit located at the Oakland Air Route Traffic Control Center and are accessible via a secure Web site. The AAZCS cameras can be zoomed and can be panned and tilted to cover a field of view 220 wide. The NOAA observer can see the sky condition as it is changing, thereby making possible a real-time evaluation of the conditions along the approach zones of SFO and SQL. The next-generation network, denoted a remote tower sensor system (RTSS), will soon be deployed at the Half Moon Bay Airport and a version of it will eventually be deployed at Los Angeles International Airport. In addition to remote control of video cameras via secure Web links, the RTSS offers realtime weather observations, remote sensing, portability, and a capability for deployment at remote and uninhabited sites. The RTSS can be used at airports that lack control towers, as well as at major airport hubs, to provide synthetic augmentation of vision for both local and remote operations under what would otherwise be conditions of low or even zero visibility.

Maluf, David A.↗

TCP Performance Enhancement Over Iridium

In support of iNET maturation, NASA-JPL has collaborated with NASA-Dryden to develop, test and demonstrate an over-the-horizon vehicle-to-ground networking capability, using Iridium as the vehicle-to-ground communications link for relaying critical vehicle telemetry. To ensure reliability concerns are met, the Space Communications Protocol Standards (SCPS) transport protocol was investigated for its performance characteristics in this environment. In particular, the SCPS-TP software performance was compared to that of the standard Transmission Control Protocol (TCP) over the Internet Protocol (IP). This paper will report on the results of this work.

distributed systems↗

Participation of HNO3 CIMS Instrument in the Sage III Ozone Loss and Validation Experiment (SOLVE)

This project was part of a larger SOLVE project led by Paul Wennberg at California Institute of Technology. The work completed on this project included participating in the installation and preflight testing of a new chemical ionization mass spectrometer for measuring gas and particle phase nitric acid on the ER-2. The investigators subsequently participated in SOLVE where additional instrument improvements were made and a substantial data set was generated. The two Georgia Tech investigators that participated in this work (Fred Eisele and Dave Tanner) had previously been responsible for much of the design and construction of the ion source and mass spectrometer which would be used to measure HNO3 in SOLVE, with Caltech focusing on inlets, calibration, gas supplies/pumping computer control, and overall integration. Thus, a similar focus remained during the SOLVE measurements though all investigators worked on most if not all aspects of the instrument at some point in the mission. Some of the more interesting results from the study included measurements of nitric acid on what are thought to be 5-20 microns diameter individual particles which could supply a local mechanism for HNO3 removal, Nitric acid measurements on SOLVE were completed as a collaborative effort with a great deal of overlap between this project and the larger parent project led by Paul Wennberg. As such, the instrumentation used, its operation, and the resulting measurements are far more fully discussed in the attached report (appendix A) which describes the joint SOLVE nitric acid measurement effort.

Eisele, F. L.↗

TAMDAR Capabilities Development

In this viewgraph presentation, information is provided on a collaboration between NASA, the FAA (Federal Aviation Administration), and NOAA (National Oceanographic and Atmospheric Association), particularly regarding the development of a TAMDAR Sensor system. TAMDAR is envisioned to downlink weather data such as icing, temperature, pressure altitude, humidity, magnetic heading, eddy dissipation rate, true airspeed, dew point, density altitude, and winds at altitude from non-jet aircraft. The weather data will be sent to FSL (Forecast Systems Laboratory), FSS (Flight Service Station), ATC (Air Traffic Control), AWC (Aviation Weather Center), and others via a ground-based infrastructure and to other aircraft. New weather products will be generated and uplinked to the cockpit.

Daniels, Taumi↗

Overview of Results from the MISSE 9-15 Polymers and Composites Experiment 1-4 (PCE 1-4)

Spacecraft in low Earth orbit (LEO) and other planetary orbits are subjected to harsh environmental conditions that can result in erosion, embrittlement and optical property degradation of susceptible materials threatening spacecraft performance and durability. To increase our understanding of space environmental effects on spacecraft materials, NASA Glenn Research Center has developed a series of experiments flown as part of the Materials International Space Station Experiment (MISSE) missions on the exterior of the International Space Station (ISS). Four Glenn experiments with 365 flight samples were flown on ISS’s MISSE-Flight Facility (MISSE-FF). These experiments are the Polymers and Composites Experiment-1 (PCE-1) flown as part of the MISSE-9 mission, the PCE-2 flown as part of the MISSE-10 mission, the PCE-3 flown as part of the MISSE-12 and MISSE-15 missions, and the PCE-4 flown as part of the MISSE-13 mission. The PCE 1-4 flight samples were flown in either ram, wake, zenith or nadir flight orientations. The primary objectives of the PCE 1-4 experiments are to determine the LEO atomic oxygen (AO) erosion yield, Ey (volume loss per incident oxygen atom) and radiation durability of spacecraft polymers, composites and coatings. In addition, each experiment has a wide variety of materials with numerous sample objectives. This presentation provides an overview of the PCE 1-4 experiments, the numerous sample collaborators, the space environmental exposure of the flight samples, and an overview of the post-flight observations and results. The results include AO fluence and contamination analyses for each mission flight orientation, erosion data for the PCE 1-4 AO Ey samples, optical property data, and tensile results for the MISSE-9 and MISSE-13 tensile samples. In addition, an introduction of results from other unique samples such as indium tin oxide (ITO) coated thermal control samples, shape memory polymer composites, melanin based composites, and specialty coatings, will be provided.

Atomic oxygen↗

The Doppler Wind Temperature Sensor (DWTS) Flight Evaluation and Experiments (TES-16, 17)

The Doppler Wind and Temperature Sounder instrument (DWTS), developed by Global Atmospheric Technologies and Sciences (GATS), is a simple but powerful tool that has the potential to become a new window through which to study the dynamics of the upper atmosphere. Based around a defense-grade infrared camera peering through a static gas cell used as a scanning spectral filter, the DWTS instrument infers wind velocities and kinetic temperatures through the stratosphere and lower thermosphere. The DWTS achieves this scanning by measuring the induced Doppler shift and Doppler broadening of emissions as they pass through the DWTS field of view (Gordley, et al., 2011). The DWTS holds promise in improving accuracy in weather determination , and the core technology can be adapted to study other planetary atmospheres. In partnership with GATS, NOAA, and other collaborators, NASA Ames and the Nano Orbital Workshop group have been working to evaluate the DWTS instrument on orbit and optimize it as a flexible nanosatellite payload. The first mission selected for DWTS evaluation is preparing for flight in early 2024, which will be followed by a more capable science mission in 2025, with both missions being part of the TES-n/NOW heritage flight series. The first rapid technology demonstration flight, TES-16/DWTS-A, will demonstrate a single DWTS instrument in an approximately 2U payload volume with the imaging aperture perpendicular to the flight velocity vector. With an estimated power consumption of 50 watts, supplied via a custom NOW-designed DC-DC converter, the instrument will maintain the imaging sensor plane at 80K during instrument evaluation periods using an integrated pulse-tube cryocooler. Data from DWTS will be captured and processed via a NOW-designed custom data interface unit before being transmitted via S-band radio back to select ground stations, with instrument command and control operated via L-band global-coverage radio. The subsequent TES-17/DWTS-B mission will be a dedicated science mission to obtain full altitude coverage from 20 to 200 km during both day and night, all from a single small-satellite equipped with three DWTS instruments, each hosting a different gas cell chemistry. The intention of this flight series, and one of NASA’s interests in this instrument, is to advance a Martian atmospheric instrument (Colaprete, Gordley, et al) which, if successful, would greatly further understanding of Martian atmospheric behavior. The proposed paper will review the flight series in detail, including challenges facing the TES-16 flight tests and the projected challenges and application to Mars study. Additional detail regarding the possible applications of a Cognitive Communication technique in current flight development by NOW collaborators at the NASA Glenn Research Center will also be discussed, including the implications of using an automated User Initiated Service (UIS) protocol to maximize the data collected per orbit.

nanosatellite↗

High resolution ultrasonic spectroscopy system for nondestructive evaluation

With increased demand for high resolution ultrasonic evaluation, computer based systems or work stations become essential. The ultrasonic spectroscopy method of nondestructive evaluation (NDE) was used to develop a high resolution ultrasonic inspection system supported by modern signal processing, pattern recognition, and neural network technologies. The basic system which was completed consists of a 386/20 MHz PC (IBM AT compatible), a pulser/receiver, a digital oscilloscope with serial and parallel communications to the computer, an immersion tank with motor control of X-Y axis movement, and the supporting software package, IUNDE, for interactive ultrasonic evaluation. Although the hardware components are commercially available, the software development is entirely original. By integrating signal processing, pattern recognition, maximum entropy spectral analysis, and artificial neural network functions into the system, many NDE tasks can be performed. The high resolution graphics capability provides visualization of complex NDE problems. The phase 3 efforts involve intensive marketing of the software package and collaborative work with industrial sectors.

Chen, C. H.↗

Industry Initiated Core Safety Attributes for Human Spaceflight for the 7th IAASS Conference

Now that the NASA Commercial Crew Program (CCP) is beginning its full certification contract for crew transportation to the International Space Station (ISS), is it time for industry to embrace a minimum set of core safety attributes? Those attributes can then be evolved into an industry-led set of basic safety standards and requirements. After 50 years of human space travel sponsored by governments, there are two basic conditions that now exist within the international space industry. The first, there is enough of a space-faring history to encourage the space industry to design, develop and operate human spaceflight systems without government contracts for anything other than services. Second, industry is capable of defining and enforcing a set of industry-based safety attributes and standards for human spaceflight to low-Earth orbit (LEO). This paper will explore both of these basic conditions with a focus on the safety attributes and standards. In the United States, the Federal Aviation Administration (FAA) is now starting to dialogue with industry about the basic safety principles and attributes needed for potential future regulatory oversight. This process is not yet formalized and will take a number of years once approval is given to move forward. Therefore, throughout the next few years, it is an excellent time and opportunity for industry to collaborate together and develop the core set of attributes and standards. As industry engages and embraces a common set of safety attributes, then government agencies, like the FAA and NASA can use that industry-based product to strengthen their efforts on a safe commercial spaceflight foundation for the future. As the commercial space industry takes the lead role in establishing core safety attributes, and then enforcing those attributes, the entire planet can move away from governmental control of design and development and let industry expand safe and successful space operations in LEO. At that point the governmental agencies can focus on oversight of the industries' defined standards and enforcement for common welfare of the space-faring populous and overall public safety.

crew transportation↗

Impact of Data Exchange Provided by ATD2 Tools at Charlotte-Douglas International Airport

Data Exchange and Integration is necessary for progress towards an Integrated Arrival, Departure, and Surface (IADS) traffic management capability. In collaboration with the FAA, NASA has introduced new data exchange elements to Charlotte-Douglas International Airport air traffic facilities, including the American Airlines ramp, as part of the Airspace Technology Demonstration 2 (ATD2). This paper describes the new tools that deliver these elements, and the human factors impact of the tools as measured by post-bank surveys. Workload was unaffected by ATD2 tool use, and situational awareness was improved in the Tower and with Ramp controllers in the second round of surveys. Respondents described their tools as more helpful if they included ATD2 tools 1) in the Tower for insuring compliance for aircraft under a Traffic Management Initiative, 2) in the TRACON when actively used for many TRACON tasks, and 3) in the Ramp in the second round of surveys.

and surface traffic management; human factors asse↗

Design and Operation of the Planetary In-Situ Capillary Electrophoresis System (PISCES)

The PISCES instrument is a portable, miniature, modular instrument designed to analyze organic molecular signatures of life. PISCES uses microcapillary electrophoresis (μCE) with laser-induced fluorescence detection (LIFD) to analyze fluorescently-labeled analytes prepared on a multi-layer microfluidic chip. As a modular instrument composed of five independently functioning units, each module can be easily detached from the system and used for subsystem testing in different environments, e.g. low temperature. The pneumatic module contains mechanical and electrical components necessary to control pneumatically-actuated valves for on-chip sample processing. A prototype LabVIEW program and two custom printed circuit boards (PCBs) operate the pneumatics module using an Arduino microcontroller, and a tentative design for the module’s housing has been developed. The high-voltage module contains circuitry required to apply varying electrical potentials to the electrophoretic channel of the microdevice. Work is currently being done to design the circuit and PCB for this module in collaboration with our SBIR partners at Los Gatos Research. The optical electronics module contains the spectrometer, laser, and laser power supply. The mounting components for the electronics and housing for the module have been designed, assembled, and tested. The optical module contains optical components to focus the laser to a 20μm spot in the center of the electrophoretic channel.The housing for this module has been designed and assembled with the aligned optical components inside.

Willis, Peter A.↗

Rapid Development of Instrument Thermal Models: Perspectives and Guidelines from NASA Goddard’s Instrument Design Laboratory

The Instrument Design Laboratory (IDL), part of NASA Goddard Space Flight Center’s Integrated Design Center (IDC), is a concurrent and collaborative environment which allows for rapid development of science instrumentation concepts within the span of less than two weeks. Science goals set by a Principal Investigator from government, industry or academia are translated into engineering requirements, from which a team of engineers spanning multiple disciplines use an established study process and a suite of analysis tools to work towards an instrument point design. As part of this process, a staff thermal engineer is tasked with designing a thermal control system which meets all incoming thermal requirements, while iterating real-time with other subsystems to ensure compatibility and functionality as a completed system. Thermal engineers on spaceflight projects typically have weeks or months to develop thermal models. However, the severe time limitation in this conceptual study setting makes thermal design particularly difficult, as rapid thermal modeling solely over the span of a few days is required to develop the instrument thermal design and understand the performance over its intended mission, especially if the instrument concept contains multiple thermal challenges such as dynamic environments or high heat dissipating components. In this paper, the authors provide a condensed guide for the most efficient ways to develop thermal models and conduct thermal analysis within the span of one-to-two weeks, as informed by decades of design experience and best practices in the IDL. The authors also focus on quick methods for determining worst-case thermal environments, deciding which modeling details are essential at this early phase, and quantifying the engineering resources necessary for thermal control. This paper concludes with specific thermal design tips for different instrument types across the electromagnetic spectrum.

Kan Yang↗

Developing a Vision for Maturing the Heliophysics Infrastructure towards Open Science: The DIARieS Analysis Ecosystem

In the dawn of open science and the upcoming requirements, we speak about the existing state of Heliophysics infrastructure and detail the evolution required to address capability or interconnection shortcomings. Such a daunting barrier calls for an analysis ecosystem with multi-faceted capability. We propose such an ecosystem, called DIARieS, to be built upon five conceptual pillars: Discovery, Implementation, Analysis, Reproducibility, and Sharing of results. The combination of these concepts in a single platform will enable users to more intuitively combine recent advances in technology to create ‘DIARieS’ of their workflows, which can be easily made open to others in the community. The DIARieS ecosystem will also increase our efficiency by streamlining our various workflow processes, including automatic incorporation of the impending requirements of open science. The various components of the ecosystem will simplify software installation and data implementation, including automatically generated citation lists based on the components included. Automatic containerization and version control of the ecosystem will make the custom workflows easily reproducible. Employing widget technology will ease the difficulty of producing publication and commercial quality visualizations and applying common analyses techniques. Incorporating multiple technologies will streamline the various sharing methods common in our work environments today. Overall, the totality of capabilities to be offered by this analysis ecosystem will drastically simplify the application of open science principles to our work in addition to improving our efficiency and ease of collaboration. This talk summarizes a vision of the proposed ecosystem, which is described in more detail in Ringuette et al. (2022: https://doi.org/10.1016/j.asr.2022.05.012).

infrastructure↗

Developing a Vision for Maturing the Heliophysics Infrastructure towards Open Science

In the dawn of open science and the upcoming requirements, we speak about the existing state of Heliophysics infrastructure and detail the evolution required to address capability or interconnection shortcomings. Such a daunting barrier calls for an analysis ecosystem with multi-faceted capability. We propose such an ecosystem, called DIARieS, to be built upon five conceptual pillars: Discovery, Implementation, Analysis, Reproducibility, and Sharing of results. The combination of these concepts in a single platform will enable users to more intuitively combine recent advances in technology to create ‘DIARieS’ of their workflows, which can be easily made open to others in the community. The DIARieS ecosystem will also increase our efficiency by streamlining our various workflow processes, including automatic incorporation of the impending requirements of open science. The various components of the ecosystem will simplify software installation and data implementation, including automatically generated citation lists based on the components included. Automatic containerization and version control of the ecosystem will make the custom workflows easily reproducible. Employing widget technology will ease the difficulty of producing publication and commercial quality visualizations and applying common analyses techniques. Incorporating multiple technologies will streamline the various sharing methods common in our work environments today. Overall, the totality of capabilities to be offered by this analysis ecosystem will drastically simplify the application of open science principles to our work in addition to improving our efficiency and ease of collaboration.

Infrastructure↗

Update of Bisphosphonate Flight Experiment

Elevated bone resorption is a hallmark of human spaceflight and bed rest indicating that elevated remodeling is a major factor in the etiology of space flight bone loss. In a collaborative effort between the NASA and JAXA space agencies, we are testing whether an antiresorptive drug would provide additional benefit to in-flight exercise to ameliorate bone loss and hypercalciuria during long-duration spaceflight. Measurements of bone loss include DXA, QCT, pQCT, urinary and blood biomarkers. We have completed analysis of R+1year data from 7 crewmembers treated with alendronate during flight, as well as immediate post flight (R+<2wks) data from 6 of 10 concurrent controls without treatment. The treated astronauts used the Advanced Resistive Exercise Device (ARED) during their missions. The purpose of this report is twofold: 1) to report the results of inflight, post flight and one year post flight bone measures compared with available controls with and without the use of ARED; and 2) to discuss preliminary data on concurrent controls. The figure below compares the BMD changes in ISS crewmembers exercising with and without the current ARED protocol and the alendronate treated crewmembers also using the ARED. This shows that the use of ARED prevents about half the bone loss seen in early ISS crewmembers and that the addition of an antiresorptive provides additional benefit. Resorption markers and urinary Ca excretion are not impacted by exercise alone but are significantly reduced with antiresorptive treatment. Bone measures for treated subjects, 1 year after return from space remain at or near baseline. DXA data for the 6 concurrent controls using the ARED device are similar to DXA data shown in the figure below. QCT data for these six indicate that the integral data are consistent with the DXA data, i.e., comparing the two control groups suggests significant but incomplete improvement in maintaining BMD using the ARED protocol. Biochemical data of the concurrent control group await sample return and analysis. The preliminary conclusion is that an antiresorptive may be an effective adjunct to exercise during long-duration spaceflight.

LeBlanc, A.↗