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Reconstruction of recycling flux from synthetic camera images, evaluated for the Wendelstein 7-X startup limiter

The interpretation of spectroscopic measurements in the edge region of high-temperature plasmas can be guided by modeling with the EMC3-EIRENE code. A versatile synthetic diagnostic module, initially developed for the generation of synthetic camera images, has been extended for the evaluation of the inverse problem in which the observable photon flux is related back to the originating particle flux (recycling). An application of this synthetic diagnostic to the startup phase (inboard) limiter in Wendelstein 7-X (W7-X) is presented, and reconstruction of recycling from synthetic observation of H α emission is evaluated. Here it is shown that recycling—in terms of re-ionization within the view cone of the camera—is underestimated by a factor of about 3 at the peak location and overestimated in between, and that H α emission related to molecular dissociation can locally yield an additional factor of 2 for the ionization to photon conversion. Fitted conversion factors are extracted from the simulation results which include a dependence on the plasma density.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

MATCHED-INDEX-OF-REFRACTION FLOW FACILITY FOR FUNDAMENTAL AND APPLIED RESEARCH

Significant challenges face reactor designers with regard to thermal hydraulic design and associated modeling for advanced reactor concepts. Computational thermal hydraulic codes solve only a piece of the core. There is a need for a whole core dynamics system code with local resolution to investigate and understand flow behavior with all the relevant physics and thermo-mechanics. The matched index of refraction (MIR) flow facility at Idaho National Laboratory (INL) has a unique capability to contribute to the development of validated computational fluid dynamics (CFD) codes through the use of state-of-the-art optical measurement techniques, such as Laser Doppler Velocimetry (LDV) and Particle Image Velocimetry (PIV). PIV is a non-intrusive velocity measurement technique that tracks flow by imaging the movement of small tracer particles within a fluid. At the heart of a PIV calculation is the cross correlation algorithm, which is used to estimate the displacement of particles in some small part of the image over the time span between two images. Generally, the displacement is indicated by the location of the largest peak. To quantify these measurements accurately, sophisticated processing algorithms correlate the locations of particles within the image to estimate the velocity (Ref. 1). Prior to use with reactor deign, the CFD codes have to be experimentally validated, which requires rigorous experimental measurements to produce high quality, multi-dimensional flow field data with error quantification methodologies. Computational thermal hydraulic codes solve only a piece of the core. There is a need for a whole core dynamics system code with local resolution to investigate and understand flow behavior with all the relevant physics and thermo-mechanics. Computational techniques with supporting test data may be needed to address the heat transfer from the fuel to the coolant during the transition from turbulent to laminar flow, including the possibility of an early laminarization of the flow (Refs. 2 and 3) (laminarization is caused when the coolant velocity is theoretically in the turbulent regime, but the heat transfer properties are indicative of the coolant velocity being in the laminar regime). Such studies are complicated enough that computational fluid dynamics (CFD) models may not converge to the same conclusion. Thus, experimentally scaled thermal hydraulic data with uncertainties should be developed to support modeling and simulation for verification and validation activities. The fluid/solid index of refraction matching technique allows optical access in and around geometries that would otherwise be impossible while the large test section of the INL system provides better spatial and temporal resolution than comparable facilities. Benchmark data for assessing computational fluid dynamics can be acquired for external flows, internal flows, and coupled internal/external flows for better understanding of physical phenomena of interest. The core objective of this study is to describe MIR and its capabilities, and mention current development areas for uncertainty quantification, mainly the uncertainty surface method and cross-correlation method. Using these methods, it is anticipated to establish a suitable approach to quantify PIV uncertainty for experiments performed in the MIR.

22 GENERAL STUDIES OF NUCLEAR REACTORS↗

SU-G-JeP2-14: MRI-Based HDR Prostate Brachytherapy: A Phantom Study for Interstitial Catheter Reconstruction with 0.35T MRI Images

Purpose: To evaluate the accuracy of interstitial catheter reconstruction with 0.35T MRI images for MRI-based HDR prostate brachytherapy. Methods: Recently, a real-time MRI-guided radiotherapy system combining a 0.35T MRI system and three cobalt 60 heads (MRIdian System, ViewRay, Cleveland, OH, USA) was installed in our department. A TrueFISP sequence for MRI acquisition at lower field on Viewray was chosen due to its fast speed and high signal-to-noise efficiency. Interstitial FlexiGuide needles were implanted into a tissue equivalent ultrasound prostate phantom (CIRS, Norfolk, Virginia, USA). After an initial 15s pilot MRI to confirm the location of the phantom, planning MRI was acquired with a 172s TrueFISP sequence. The pulse sequence parameters included: flip angle = 60 degree, echo time (TE) =1.45 ms, repetition time (TR) = 3.37 ms, slice thickness = 1.5 mm, field of view (FOV) =500 × 450mm. For a reference image, a CT scan was followed. The CT and MR scans were then fused with the MIM Maestro (MIM software Inc., Cleveland, OH, USA) and sent to the Oncentra Brachy planning system (Elekta, Veenendaal, Netherlands). Automatic catheter reconstruction using CT and MR image intensities followed by manual reconstruction was used to digitize catheters. The accuracy of catheter reconstruction was evaluated from the catheter tip location. Results: The average difference between the catheter tip locations reconstructed from the CT and MR in the transverse, anteroposterior, and craniocaudal directions was −0.1 ± 0.1 mm (left), 0.2 ± 0.2 mm (anterior), and −2.3 ± 0.5 mm (cranio). The average distance in 3D was 2.3 mm ± 0.5 mm. Conclusion: This feasibility study proved that interstitial catheters can be reconstructed with 0.35T MRI images. For more accurate catheter reconstruction which can affect final dose distribution, a systematic shift should be applied to the MR based catheter reconstruction in HDR prostate brachytherapy.

60 APPLIED LIFE SCIENCES↗

3D inpatient dose reconstruction from the PET-CT imaging of {sup 90}Y microspheres for metastatic cancer to the liver: Feasibility study

Purpose: The introduction of radioembolization with microspheres represents a significant step forward in the treatment of patients with metastatic disease to the liver. This technique uses semiempirical formulae based on body surface area or liver and target volumes to calculate the required total activity for a given patient. However, this treatment modality lacks extremely important information, which is the three-dimensional (3D) dose delivered by microspheres to different organs after their administration. The absence of this information dramatically limits the clinical efficacy of this modality, specifically the predictive power of the treatment. Therefore, the aim of this study is to develop a 3D dose calculation technique that is based on the PET imaging of the infused microspheres.Methods: The Fluka Monte Carlo code was used to calculate the voxel dose kernel for {sup 90}Y source with voxel size equal to that of the PET scan. The measured PET activity distribution was converted to total activity distribution for the subsequent convolution with the voxel dose kernel to obtain the 3D dose distribution. In addition, dose-volume histograms were generated to analyze the dose to the tumor and critical structures.Results: The 3D inpatient dose distribution can be reconstructed from the PET data of a patient scanned after the infusion of microspheres. A total of seven patients have been analyzed so far using the proposed reconstruction method. Four patients underwent treatment with SIR-Spheres for liver metastases from colorectal cancer and three patients were treated with Therasphere for hepatocellular cancer. A total of 14 target tumors were contoured on post-treatment PET-CT scans for dosimetric evaluation. Mean prescription activity was 1.7 GBq (range: 0.58–3.8 GBq). The resulting mean maximum measured dose to targets was 167 Gy (range: 71–311 Gy). Mean minimum dose to 70% of target (D70) was 68 Gy (range: 25–155 Gy). Mean minimum dose to 90% of target (D90) was 53 Gy (range: 13–125 Gy).Conclusions: A three-dimensional inpatient dose reconstruction method has been developed that is based on the PET/CT data of a patient treated with {sup 90}Y microspheres. It allows for a complete description of the absorbed dose by the tumor and critical structures. It represents the first step in building predictive models for treatment outcomes for patients receiving this therapeutic modality as well as it allows for better analysis of patients' dose response and will ultimately improve future treatment administration.

61 RADIATION PROTECTION AND DOSIMETRY↗

Emission spectroscopy with coded apertures for enhanced dimensionality

A coded aperture is used to demonstrate emission spectroscopy from multiple one-dimensional measurement locations simultaneously with a single camera. The coded aperture mask has several columns of periodic apertures, each with a unique spatial frequency. Light transmitted through all mask columns is detected through an imaging spectrometer. Dispersed light from the various mask columns overlaps on the spectrometer camera but is separated using Fourier-domain filtering using the known spatial frequencies of the mask. As the coded aperture is placed at an image plane, each Fourier-filtered spectrogram comes from a unique one-dimensional measurement location. This technique represents a significant increase in the amount of spatially and spectrally resolved emission data available using a single emission spectrometer and camera at the expense of some spatial resolution due to the Fourier filtering. This instrument is particularly useful for studying transient, non-repeating events. Megahertz-rate emission spectroscopy from five one-dimensional measurement locations is demonstrated with explosive fireballs using a single camera. Optical design parameters and instrument performance characteristics are discussed.

42 ENGINEERING↗

Ultrasonic power measurement system based on acousto-optic interaction

Ultrasonic waves are widely used, with applications including the medical, military, and chemical fields. However, there are currently no effective methods for ultrasonic power measurement. Previously, ultrasonic power measurement has been reliant on mechanical methods such as hydrophones and radiation force balances. This paper deals with ultrasonic power measurement based on an unconventional method: acousto-optic interaction. Compared with mechanical methods, the optical method has a greater ability to resist interference and also has reduced environmental requirements. Therefore, this paper begins with an experimental determination of the acoustic power in water contained in a glass tank using a set of optical devices. Because the light intensity of the diffraction image generated by acousto-optic interaction contains the required ultrasonic power information, specific software was written to extract the light intensity information from the image through a combination of filtering, binarization, contour extraction, and other image processing operations. The power value can then be obtained rapidly by processing the diffraction image using a computer. The results of this work show that the optical method offers advantages that include accuracy, speed, and a noncontact measurement method.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

In-line, High-Throughput Quality Monitoring for Fuel Cell and Electrolyzer Components Based on Transmission and Reflection Imaging

During the manufacturing of fuel cell and electrolyzer membranes and membrane electrode assemblies (MEAs), real-time, in-line, high-throughput optical-based quality monitoring methods are essential for detecting defects and monitoring thickness variations, thus improving the performance and increasing the durability of fuel cell and electrolyzer in the hydrogen industry. For the MEAs with very opaque coatings, optical transmission-based imaging has been developed and applied in the Roll-to-Roll system using a flashlight and a high-sensitivity CCD camera. We observed high signal-to-noise ratio images while the Roll-to-Roll system ran at 5 ft/min. The entire sample image could quickly be recovered from the discrete frames using customized Python codes for automatic frame cropping and stitching. We detected significant non-uniformities in our experimental MEAs specimen. For fuel cell and low-temperature electrolysis (LTE) transparent membranes, we used optical reflectance hyperspectral imaging with interference fringe-based thickness mapping. We set up a hyperspectral camera to measure various rolls of commercial membranes. The measurement results are analyzed to find the thickness distribution of each roll and to check for defects. Transmission and reflection imaging-based quality monitoring techniques demonstrated in this project can be widely used in the mass production environment to improve the production yield and performance of hydrogen devices.

DIRECT ENERGY CONVERSION,ENGINEERING↗

Digital Image Correlation Engine v.3.0

DICe is an open source digital image correlation (DIC) tool intended for use as a module in an external application or as a standalone analysis code. It's primary capability is computing full-field displacements and strains from sequences of digital These images are typically of a material sample undergoing a materials characterization experiment, but DICe is also useful for other applications (for example, trajectory tracking). DICe is machine portable (Windows, Linux and Mac) and can be effectively deployed on a high performance computing platform. Capabilities from DICe can be invoked through a library interface, via source code integration of DICe classes or through a graphical user interface.

Turner, Dan↗

SU-F-J-47: Inherent Uncertainty in the Positional Shifts Determined by a Volumetric Cone Beam Imaging System

Purpose: To quantify inherent uncertainty associated with a volumetric imaging system in its determination of positional shifts. Methods: The study was performed on an Elekta Axesse™ linac’s XVI cone beam computed tomography (CBCT) system. A CT image data set of a Penta- Guide phantom was used as reference image by placing isocenter at the center of the phantom.The phantom was placed arbitrarily on the couch close to isocenter and CBCT images were obtained. The CBCT dataset was matched with the reference image using XVI software and the shifts were determined in 6-dimensions. Without moving the phantom, this process was repeated 20 times consecutively within 30 minutes on a single day. Mean shifts and their standard deviations in all 6-dimensions were determined for all the 20 instances of imaging. For any given day, the first set of shifts obtained was kept as reference and the deviations of the subsequent 19 sets from the reference set were scored. Mean differences and their standard deviations were determined. In this way, data were obtained for 30 consecutive working days. Results: Tabulating the mean deviations and their standard deviations observed on each day for the 30 measurement days, systematic and random errors in the determination of shifts by XVI software were calculated. The systematic errors were found to be 0.03, 0.04 and 0.03 mm while random errors were 0.05, 0.06 and 0.06 mm in lateral, craniocaudal and anterio-posterior directions respectively. For rotational shifts, the systematic errors were 0.02°, 0.03° and 0.03° and random errors were 0.06°, 0.05° and 0.05° in pitch, roll and yaw directions respectively. Conclusion: The inherent uncertainties in every image guidance system should be assessed and baseline values established at the time of its commissioning. These shall be periodically tested as part of the QA protocol.

60 APPLIED LIFE SCIENCES↗

Automated Defect Identification For Triso Fuels

The developed code is to be used to identify manufacturing defects of nuclear fuel kernels using image processing methods. Past batches of TRi-structural ISOtropic particle (TRISO) fuel kernels have on occasion contained fissures that result in the fuel batch not meeting specifications. The developed code automates the inspection process of these kernels. The code analyzes micrographs of TRISO fuel kernels and outputs a count of total kernels in the sample, a count of the number of defective particles in the sample, as well as processed images for more effective manual inspection. This information output will be used to help identify if defective kernels are present in a fuel batch and quantify the countable fissure fraction.

Oncken, JosephE.↗

Inverse Regression for Extraction of Tumor Site from Cancer Pathology Reports

Pathology reports are the primary source of information for cancer diagnosis of millions of the cancer patients across the United States. Cancer registries label these reports every year. The coded labels incorporate pertinent information such as cancer location, behavior, and histology. This information when combined with clinical information, medical imaging and even genomic information have a great potential to fuel discoveries in cancer research. The coding process is manual and requires many human experts to label the large volume of pathology reports in a timely manner. In this study, we have developed a supervised inverse regression based auto-labeler to automate the task. The experiments were conducted on a set of 942 pathology reports with human expert labels as the ground truth. We observed that the inverse regression based auto-labeler consistently performed better than or comparable to the best performing state-of-the-art method. These results demonstrate the potential of inverse regression for reliable information extraction from the pathology reports.

Dubey, Abhishek↗

KINEMATICS OF SUPERBUBBLES AND SUPERSHELLS IN THE IRREGULAR GALAXY, NGC 1569

We present observations in the optical lines of Hα and [S II] (λλ6717, 6731 Å) and in X-rays of the irregular galaxy, NGC 1569. The observations in Hα and [S II] were made with the UNAM scanning Fabry-Perot interferometer (PUMA) and the X-ray data were obtained from the Chandra data archive. We detected several superbubbles, filaments, and supershells in NGC 1569 for which we determined size as well as their kinematic properties. We present a catalog of expansion velocities of 12 superbubbles, listing their positions, diameters, and physical parameters. Likewise, we present a catalog of 15 filaments and 4 supershells. In order to identify possible X-ray emission from the superbubbles in this galaxy, we analyzed the X-ray emission of NGC 1569 in two energy bands: 0.2-2.0 keV (soft X-rays) and 2.0-8.0 keV (hard X-rays). Based on X-ray images, we detected X-ray emission that could possibly be related to some of the superbubbles. The spectrum of the X-ray superbubbles can be described by an optically thin thermal plasma model. In order to identify the possible coexistence of galactic super winds and superbubbles we have performed adiabatic three-dimensional N-body/smoothed particle hydrodynamics simulations to follow the evolution of the most important stellar clusters in this galaxy, SSC A and SSC B, using the GADGET-2 code. Those simulations demonstrate that depending on the specific initial conditions, the formation of superbubbles or a galactic superwind can result in NGC 1569.

79 ASTRONOMY AND ASTROPHYSICS↗

Pore-Scale and Multiscale Numerical Simulation of Flow and Transport in a Laboratory-Scale Column

Pore-scale models are useful for studying relationships between fundamental processes and phenomena at larger (i.e., Darcy) scales. However, the size of domains that can be simulated with explicit pore-scale resolution is limited by computational and observational constraints. Direct numerical simulation of pore-scale flow and transport is typically performed on millimeter-scale volumes at which X-ray computed tomography (XCT), often used to characterize pore geometry, can achieve micrometer resolution. In contrast, the scale at which a continuum approximation of a porous medium is valid is usually larger, on the order of centimeters to decimeters. Furthermore, laboratory experiments that measure continuum properties are typically performed on decimeter-scale columns. At this scale, XCT resolution is coarse (tens to hundreds of micrometers) and prohibits characterization of small pores and grains. We performed simulations of pore-scale processes over a decimeter-scale volume of natural porous media with a wide range of grain sizes, and compared to results of column experiments using the same sample. Simulations were conducted using high-performance codes executed on a supercomputer. Two approaches to XCT image segmentation were evaluated, a binary (pores and solids) segmentation and a ternary segmentation that resolved a third category (porous solids with pores smaller than the imaged resolution). We used a mixed Stokes-Darcy simulation method to simulate the combination of Stokes flow in large open pores and Darcy-like flow in porous solid regions. Simulations based on the ternary segmentation provided results that were consistent with experimental observations, demonstrating our ability to successfully model pore-scale flow over a column-scale domain.

CFD↗

Parameterizing hot electron energy distributions for tabular emissivities and opacities

Cold Kα and Kβ emission spectroscopy is a powerful diagnostic for plasma conditions and distributions of energetic electrons produced in short pulse laser experiments. SPECT3D post-processes hydrodynamics code output and simulates high-resolution spectra and images for plasmas containing arbitrary distributions of hot electrons, however these calculations can become prohibitively expensive for plasmas requiring complex atomic data and detailed computational grids. To significantly increase calculation speed, it is desirable to use pre-configured opacity tables that include information about hot electrons, rather than calculating emissivity and opacity for every grid point by solving collisional-radiative atomic kinetic rate equations. However, to tabulate such opacities, a general parameter-based description of hot electron energy distributions must be found. To be practical, hot electrons should be represented with an analytic function of just a few parameters which, in addition to temperature and density, can be used to define parameter space for opacity tables. In this paper, we present a method that allows for describing a set of arbitrary binned hot electron distributions with a simple analytic function, with only a modest impact on the accuracy of the simulations. Increased calculation speeds of 50–100x are demonstrated. In conclusion, we also discuss details of opacity calculations and present synthetic spectroscopy data based on post-processing of detailed particle-in-cell simulations relevant to the ongoing experimental campaign at the Omega EP laser facility.

74 ATOMIC AND MOLECULAR PHYSICS↗

Phase contrast imaging measurements and numerical simulations of turbulent density fluctuations in gas-fuelled ECRH discharges in Wendelstein 7-X

The fundamental nature of turbulent density fluctuations in standard Wendelstein 7-X (W7-X) stellarator discharges is investigated experimentally via phase contrast imaging (PCI) in combination with gyrokinetic simulations with the code GENE. We find that density fluctuations are ion-temperature-gradient-driven and radially localised in the outer half of the plasma. It is shown that the line-integrated PCI measurements cover the right range of wavenumbers and a favourable toroidal and poloidal location to capture some of the strongest density fluctuations in W7-X. Due to the radial localisation of fluctuations, measured wavenumber–frequency spectra exhibit a dominant phase velocity, which can be related to the E × B rotation velocity at the radial position of a well in the neoclassical radial electric field. The match is robust against variations of heating power and line-integrated density, which is partly due to the localisation of fluctuations and partly due to effects of the radial gradient in the E × B velocity profile on the wavenumber–frequency spectrum. The latter effect is studied with a newly built synthetic PCI diagnostic and global gyrokinetic simulations with GENE-3D.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

Study of shock waves and related phenomena motivated by astrophysics

This study discusses the recent research in High-Energy-Density Physics at our Center. Our work in complex hydrodynamics is now focused on mode coupling in the Richtmyer-Meshkov process and on the supersonic Kelvin-Helmholtz instability. These processes are believed to occur in a wide range of astrophysical circumstances. In radiation hydrodynamics, we are studying radiative reverse shocks relevant to cataclysmic variable stars. Our work on magnetized flows seeks to produce magnetized jets and study their interactions. We build the targets for all these experiments, and simulate them using our CRASH code. We also conduct diagnostic research, focused primarily on imaging x-ray spectroscopy and its applications to scattering and fluorescence.

79 ASTRONOMY AND ASTROPHYSICS↗

SU-F-T-119: Development of Heart Prediction Model to Increase Accuracy of Dose Reconstruction for Radiotherapy Patients

Purpose: To assess individual variation in heart volume and location in order to develop a prediction model of the heart. This heart prediction model will be used to calculate individualized heart doses for radiotherapy patients in epidemiological studies. Methods: Chest CT images for 30 adult male and 30 adult female patients were obtained from NIH Clinical Center. Image-analysis computer programs were used to segment the whole heart and 8 sub-regions and to measure the volume of each sub- region and the dimension of the whole heart. An analytical dosimetry method was used for the 30 adult female patients to estimate mean heart dose during conventional left breast radiotherapy. Results: The average volumes of the whole heart were 803.37 cm{sup 3} (COV 18.8%) and 570.19 cm{sup 3} (COV 18.8%) for adult male and female patients, respectively, which are comparable with the international reference volumes of 807.69 cm{sup 3} for males and 596.15 cm{sup 3} for females. Some patient characteristics were strongly correlated (R{sup 2}>0.5) with heart volume and heart dimensions (e.g., Body Mass Index vs. heart depth in males: R{sup 2}=0.54; weight vs. heart width in the adult females: R{sup 2}=0.63). We found that the mean heart dose 3.805 Gy (assuming prescribed dose of 50 Gy) in the breast radiotherapy simulations of the 30 adult females could be an underestimate (up to 1.6-fold) or overestimate (up to 1.8-fold) of the patient-specific heart dose. Conclusion: The study showed the significant variation in patient heart volumes and dimensions, resulting in substantial dose errors when a single average heart model is used for retrospective dose reconstruction. We are completing a multivariate analysis to develop a prediction model of the heart. This model will increase accuracy in dose reconstruction for radiotherapy patients and allow us to individualize heart dose calculations for patients whose CT images are not available.

60 APPLIED LIFE SCIENCES↗

Parallel Monte Carlo Methods for Heterogeneous Hardware Computer Systems Using GPUs and Coprocessors: Recent Development of ARCHER Code - Paper 54

Traditional methods of accelerating Monte Carlo (MC) calculations typically use CPUs as the computing unit. The parallelism is based upon multithreading on a multi-core processor, and message passing interface (MPI) across many processors and nodes. In recent years, the hardware accelerators have been introduced by the high performance computing industry as an alternative approach to achieve massive parallelism. Hardware accelerators have the advantage of high Floating-point Operations Per Second (FLOPS) and high energy efficiency. Examples include graphics processing units (GPUs) and coprocessors. Compute-intensive programs can be off-loaded to them to be concurrently executed by hundreds or thousands of active threads. Existing production MC codes, however, cannot be directly compiled or executed on the new platforms. It is therefore necessary to rewrite or redevelop the code using the hardware accelerator specific programming models and APIs. Several studies have been conducted on using GPUs to accelerate MC calculations in reactor analysis and medical physics. In this paper, we present the recent progress at Rensselaer Polytechnic Institute (RPI) in developing a new parallel MC code called ARCHER (Accelerated Radiation-transport Computations in Heterogeneous Environments) for coupled photon-electron transport simulations. The code is designed as a test bed to evaluate the efficacy of heterogeneous computing systems for low-cost MC-based radiation dosimetric calculations. The code has three variants corresponding to three parallel hardware platforms: ARCHER-CPU (multi-core CPU), ARCHER-GPU (Nvidia GPU) and ARCHER-COP (Intel Xeon Phi coprocessor). The code has been used for several applications, including CT imaging dosimetry, radiotherapy dosimetry and radiation shielding design. (authors)

61 RADIATION PROTECTION AND DOSIMETRY↗