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At least 631 records · Page 35

Paternal Imprinting of Dosage-Effect Defective1 Contributes to Seed Weight Xenia in Maize4

Historically, xenia effects were hypothesized to be unique genetic contributions of pollen to seed phenotype, but most examples represent standard complementation of Mendelian traits. We identified the imprinted dosage-effect defective1 (ded1) locus in maize (Zea mays) as a paternal regulator of seed size and development. Hypomorphic alleles show a 5-10% seed weight reduction when ded1 is transmitted through the male, while homozygous mutants are defective with a 70-90% seed weight reduction. Ded1 encodes an R2R3-MYB transcription factor expressed specifically during early endosperm development with paternal allele bias. DED1 directly activates early endosperm genes and endosperm adjacent to scutellum cell layer genes, while directly repressing late grain-fill genes. These results demonstrate xenia as originally defined: Imprinting of Ded1 causes the paternal allele to set the pace of endosperm development thereby influencing grain set and size.

Genomics↗

Experimental investigations of He II flows at high Reynolds number

Fluid dynamics studies of He II at high Reynolds number (Re(d) greater than 10 exp 6) reveal characteristics which are best interpreted in terms of classical scaling relationships. In particular, the smooth tube friction factor is seen to correlate with the Von Karman-Nikuradse formulation. Also, the performance of a centrifugal pump is unchanged whether being used with He I or He II. These effects are expected to result provided the He II possesses a viscous sublayer and that the drag is determined by laminar flow within this layer. On the other hand, heat transfer in He II is substantially different from that of He I because of the unique internal convection mechanism present in this quantum fluid. These experiments are performed in the University of Wisconsin liquid helium flow facility which has unique capabilities of He II temperature, pressure and flow.

Van Sciver, Steve W.↗

Design and Analysis of the International X-Ray Observatory Mirror Modules

The Soft X-Ray Telescope (SXT) modules are the fundamental focusing assemblies on NASA's next major X-ray telescope mission, the International X-Ray Observatory (IXO). The preliminary design and analysis of these assemblies has been completed, addressing the major engineering challenges and leading to an understanding of the factors effecting module performance. Each of the 60 modules in the Flight Mirror Assembly (FMA) supports 200-300 densely packed 0.4 mm thick glass mirror segments in order to meet the unprecedented effective area required to achieve the scientific objectives of the mission. Detailed Finite Element Analysis (FEA), materials testing, and environmental testing have been completed to ensure the modules can be successfully launched. Resulting stress margins are positive based on detailed FEA, a large factor of safety, and a design strength determined by robust characterization of the glass properties. FEA correlates well with the results of the successful modal, vibration, and acoustic environmental tests. Deformation of the module due to on-orbit thermal conditions is also a major design driver. A preliminary thermal control system has been designed and the sensitivity of module optical performance to various thermal loads has been determined using optomechanical analysis methods developed for this unique assembly. This design and analysis furthers the goal of building a module that demonstrates the ability to meet IXO requirements, which is the current focus of the IXO FMA technology development team.

McClelland, Ryan S.↗

POEMMA's Target of Opportunity Sensitivity to Cosmic Neutrino Transient Sources

We calculate the sensitivity of space-based cosmic neutrino detection from transient sources in the context of the Probe Of Extreme Multi-Messenger Astrophysics (POEMMA) mission using Target- of-Opportunity (ToO) observations. POEMMA uses two spacecraft each with a large Schmidt telescope to simultaneously view the optical signals generated by extensive air showers (EASs). POEMMA is designed for both ultrahigh-energy cosmic ray and very-high-energy neutrino measurements. POEMMA has significant neutrino sensitivity starting in the 10 PeV decade via measurements of Cherenkov signals from upward-moving EASs initiated by tau neutrinos interacting in the Earth. For ToO observations, POEMMA uses the ability to quickly repoint (90° in 500 seconds) each of the two spacecraft to the direction of the transient source. POEMMA EAS measurements are performed during astronomical night, leading to different observational constraints for short- and long-duration bursts. For short-bursts of order 10(exp 3) s, POEMMA will increase the sensitivity of existing experiments (e.g., IceCube and the Pierre Auger Observatory) by up to two orders of magnitude. For long-duration bursts on the scale of 10(exp 5−6) s, the full celestial sky is available and the average neutrino sensitivity will be increased by up to a factor of 50, reaching the desired level to probe model predictions of transient neutrino sources (e.g., of blazer flares as well as both black hole-black hole and neutron star-neutron star mergers). POEMMA’s neutrino sensitivity to various models of transient neutrino sources are detailed. Altogether, our results demonstrate better sensitivity to ToO neutrino sources from the space-based POEMMA experiment compared to current ground-based experiments, and more importantly, demonstrate unique full-sky coverage for ToO neutrino sources.

Venters, Tonia M.↗

High performance visible and near-infrared charge-coupled-device array for spectroscopy applications

This paper describes the design and performance of a scientific CCD array for use in NASA's Shuttle Image Spectrometer Experiment. The device is a four-phase, buried-channel CCD structure that operates in the frame-transfer mode. The sensor consists of 64 x 404 pixels, has a 100 percent fill factor, and operates in the visible and near-infrared spectral regions. In operation, the 404 horizontal elements provide spatial information, while the 64 vertical elements give spectral information covering the wavelength range of 400 to 1000 nm in 10 nm increments. The high full-well capacity of each pixel and low noise floor yield a dynamic range of more than 95 dB. In addition, the device has been designed to have good linearity characteristics. The unique dual-output structure allows a horizontal row to be read out to the right or to the left, or it can be split from the middle to both right and left output circuits simultaneously for high speed applications. The power dissipation of the device is about 60 mW.

Wang, Weng-Lyang↗

NASA Remote Sensing Data for Epidemiological Studies

In response to the need for improved observations of environmental factors to better understand the links between human health and the environment, NASA has established a new program to significantly improve the utilization of NASA's diverse array of data, information, and observations of the Earth for health applications. This initiative, lead by Goddard Space Flight Center (GSFC) has the following goals: (1) To encourage interdisciplinary research on the relationships between environmental parameters (e.g., rainfall, vegetation) and health, (2) Develop practical early warning systems, (3) Create a unique system for the exchange of Earth science and health data, (4) Provide an investigator field support system for customers and partners, (5) Facilitate a system for observation, identification, and surveillance of parameters relevant to environment and health issues. The NASA Environment and Health Program is conducting several interdisciplinary projects to examine applications of remote sensing data and information to a variety of health issues, including studies on malaria, Rift Valley Fever, St. Louis Encephalitis, Dengue Fever, Ebola, African Dust and health, meningitis, asthma, and filariasis. In addition, the NASA program is creating a user-friendly data system to help provide the public health community with easy and timely access to space-based environmental data for epidemiological studies. This NASA data system is being designed to bring land, atmosphere, water and ocean satellite data/products to users not familiar with satellite data/products, but who are knowledgeable in the Geographic Information Systems (GIS) environment. This paper discusses the most recent results of the interdisciplinary environment-health research projects and provides an analysis of the usefulness of the satellite data to epidemiological studies. In addition, there will be a summary of presently-available NASA Earth science data and a description of how it may be obtained.

Maynard, Nancy G.↗

A Bioinformatics Facility for NASA

Building on an existing prototype, we have fielded a facility with bioinformatics technologies that will help NASA meet its unique requirements for biological research. This facility consists of a cluster of computers capable of performing computationally intensive tasks, software tools, databases and knowledge management systems. Novel computational technologies for analyzing and integrating new biological data and already existing knowledge have been developed. With continued development and support, the facility will fulfill strategic NASA s bioinformatics needs in astrobiology and space exploration. . As a demonstration of these capabilities, we will present a detailed analysis of how spaceflight factors impact gene expression in the liver and kidney for mice flown aboard shuttle flight STS-108. We have found that many genes involved in signal transduction, cell cycle, and development respond to changes in microgravity, but that most metabolic pathways appear unchanged.

Schweighofer, Karl↗

Yb14MnSb11 as a High-Efficiency Thermoelectric Material

Yb14MnSb11 has been found to be wellsuited for use as a p-type thermoelectric material in applications that involve hotside temperatures in the approximate range of 1,200 to 1,300 K. The figure of merit that characterizes the thermal-to-electric power-conversion efficiency is greater for this material than for SiGe, which, until now, has been regarded as the state-of-the art high-temperature ptype thermoelectric material. Moreover, relative to SiGe, Yb14MnSb11 is better suited to incorporation into a segmented thermoelectric leg that includes the moderate-temperature p-type thermoelectric material CeFe4Sb12 and possibly other, lower-temperature p-type thermoelectric materials. Interest in Yb14MnSb11 as a candidate high-temperature thermoelectric material was prompted in part by its unique electronic properties and complex crystalline structure, which place it in a class somewhere between (1) a class of semiconducting valence compounds known in the art as Zintl compounds and (2) the class of intermetallic compounds. From the perspective of chemistry, this classification of Yb14MnSb11 provides a first indication of a potentially rich library of compounds, the thermoelectric properties of which can be easily optimized. The concepts of the thermoelectric figure of merit and the thermoelectric compatibility factor are discussed in Compatibility of Segments of Thermo - electric Generators (NPO-30798), which appears on page 55. The traditional thermoelectric figure of merit, Z, is defined by the equation Z = alpha sup 2/rho K, where alpha is the Seebeck coefficient, rho is the electrical resistivity, and k is the thermal conductivity.

Snyder, G. Jeffrey↗

Validation of Test Methods for Air Leak Rate Verification of Spaceflight Hardware

As deep space exploration continues to be the goal of NASAs human spaceflight program, verification of the performance of spaceflight hardware becomes increasingly critical. Suitable test methods for verifying the leak rate of sealing systems are identified in program qualification testing requirements. One acceptable method for verifying the air leak rate of gas pressure seals is the tracer gas leak detector method. In this method, a tracer gas (commonly helium) leaks past the test seal and is transported to the leak detector where the leak rate is quantified. To predict the air leak rate, a conversion factor of helium-to-air is applied depending on the magnitude of the helium flow rate. The conversion factor is based on either the molecular mass ratio or the ratio of the dynamic viscosities. The current work was aimed at validating this approach for permeation-level leak rates using a series of tests with a silicone elastomer O-ring. An established pressure decay method with constant differential pressure was used to evaluate both the air and helium leak rates of the O-ring under similar temperature and pressure conditions. The results from the pressure decay tests showed, for the elastomer O-ring, that neither the molecular flow nor the viscous flow helium-to-air conversion factors were applicable. Leak rate tests were also performed using nitrogen and argon as the test gas. Molecular mass and viscosity based helium-to-test gas conversion factors were applied, but did not correctly predict the measured leak rates of either gas. To further this study, the effect of pressure boundary conditions was investigated. Often, pressure decay leak rate tests are performed at a differential pressure of 101.3 kPa with atmospheric pressure on the downstream side of the test seal. In space applications, the differential pressure is similar, but with vacuum as the downstream pressure. The same O-ring was tested at four unique differential pressures ranging from 34.5 to 137.9 kPa. Up to six combinations of upstream and downstream pressures for each differential pressure were compared. For a given differential pressure, the various combinations of upstream and downstream dry air pressures did not significantly affect the leak rate. As expected, the leak rate of the O-ring increased with increasing differential pressure. The results suggested that the current leak test pressure conditions, used to verify spacecraft sealing systems with elastomer seals, produce accurate values even though the boundary conditions do not model the space application.

helium leak detector↗

An overview of artificial gravity

The unique characteristics of artificial gravity that affect human performance and physiology in an artificial gravity environment are reviewed. The rate at which these unique characteristics change decreases very rapidly with increasing radius of a rotating vehicle used to produce artificial gravity. Reducing their influence on human performance or physiology by increasing radius becomes a situation of very rapidly diminishing returns. A review of several elements of human performance has developed criteria relative to the sundry characteristics of artificial gravity. A compilation of these criteria indicates that the maximum acceptable rate of rotation, leg heaviness while walking, and material handling are the factors that define the minimum acceptable radius. The ratio of Coriolis force to artificial weight may also be significant. Based on current knowledge and assumptions for the various criteria, a minimum radius between 15.2 and 16.8 m seems desirable.

Ralph W. Stone Jr.↗

The art of spacecraft design: A multidisciplinary challenge

Actual design turn-around time has become shorter due to the use of optimization techniques which have been introduced into the design process. It seems that what, how and when to use these optimization techniques may be the key factor for future aircraft engineering operations. Another important aspect of this technique is that complex physical phenomena can be modeled by a simple mathematical equation. The new powerful multilevel methodology reduces time-consuming analysis significantly while maintaining the coupling effects. This simultaneous analysis method stems from the implicit function theorem and system sensitivity derivatives of input variables. Use of the Taylor's series expansion and finite differencing technique for sensitivity derivatives in each discipline makes this approach unique for screening dominant variables from nondominant variables. In this study, the current Computational Fluid Dynamics (CFD) aerodynamic and sensitivity derivative/optimization techniques are applied for a simple cone-type forebody of a high-speed vehicle configuration to understand basic aerodynamic/structure interaction in a hypersonic flight condition.

Abdi, F.↗

On origin of the olivine inclusions from the Kainsaz CO carbonaceous chondrite

Olivine inclusions and chondrules of Kainsaz were formed in a unique process of dust matter melting. The elemental abundances of four fractions of olivine (01) inclusions from Kainsaz were analyzed by INAA. The inclusions of fraction A (160 less than d less than 260 microns) have Fe-Ni grains, the inclusions of fractions B (100 less than d less than 160 microns), C (160 less than d less than 260 microns), and D (260 less than d less than 360 microns) do not. The average elemental enrichment factors relative to CI chondrite for each fraction and chondrules of Kainsaz is shown. The enrichment factors of siderophile Co, Ni, Ir, Au, and non-refractory Na in all fractions are less than 1. The factors of refractory Ca, Sc, La, Sm, and Yb are comparative with the corresponding values of O1 aggregates of Allende CV (average 4.76). For chondrules of Kainsaz these values are lower. Fraction A is enriched in Co, Ir, Au, and relative Ni and CI chondrites: Ir greater than Au greater than Co. The values of (Me/Ni)inc/(Me/Ni)CI are equal to 3.25 for Ir, 2.1 for Au, and 1.2 for Co. The superabundances in Ir and Au relative to Ni witness to formation of Fe-Ni grains of O1 inclusions by agglomeration of grains enriched in refractory metal with grains enriched in non-refractory metal (Au). The enrichments of fraction A in Ca, Sc, La, Sm, and Yb witness about presence of high-temperature phases in O1 inclusions.

Lavrukhina, A. K.↗

Some questions of space bioengineering

Zero-gravity offers selective effect on growth and metabolic activity unicellular organisms as well as unique opportunities in purification of organic compounds. These make it possible to consider the biosynthesis and recovery of certain metabolites economically feasible in space. Design, construction and operation of systems for the above mentioned purposes requires interdisciplinary actions within the scope of a new discipline: space bioengineering. The problems and perspectives of this discipline particularly in the application of bioreactor-recovery systems in space to manufacture metabolites of high economic and scientific value. Special attention is paid to pivotal factors such as various mass transport phenomena, contamination control, automatic control of optimum environment and synchronization of the operation of the biological (biosynthesis) and the physiochemical (recovery-purification) systems.

Nyiri, L. K.↗

Astronaut hazard during free-flight polar EVA

Extravehicular Activity (EVA) during Shuttle flights planned for the late 1980's includes several factors which together may constitute an astronaut hazard. Free-flight EVA is planned whereas prior United States Earth orbit EVA has used umbilical tethers carrying communications, coolant, and oxygen. EVA associated with missions like LANDSAT Retrieval will be in orbits through the auroral oval where charging of spacecraft may occur. The astronaut performing free flight EVA constitutes an independent spacecraft. The astronaut and the Shuttle make up a system of electrically isolated spacecraft with a wide disparity in size. Unique situations, such as the astronaut being in the wake of the Shuttle while traversing an auroral disturbance, could result in significant astronaut and Shuttle charging. Charging and subsequent arc discharge are important because they have been associated with operating upsets and even satellite failure at geosynchronous orbit. Spacecraft charging theory and experiments are examined to evaluate charging for Shuttle size spacecraft in the polar ionosphere.

Hall, W. N.↗

NASA reports

Activities and National Aeronautics and Space Administration (NASA) programs, both ongoing and planned, are described by NASA administrative personnel from the offices of Space Science and Applications, Space Systems Development, Space Flight, Exploration, and from the Johnson Space Center. NASA's multi-year strategic plan, called Vision 21, is also discussed. It proposes to use the unique perspective of space to better understand Earth. Among the NASA programs mentioned are the Magellan to Venus and Galileo to Jupiter spacecraft, the Cosmic Background Explorer, Pegsat (the first Pegasus payload), Hubble, the Joint U.S./German ROSAT X-ray Mission, Ulysses to Jupiter and over the sun, the Astro-Spacelab Mission, and the Gamma Ray Observatory. Copies of viewgraphs that illustrate some of these missions, and others, are provided. Also discussed were life science research plans, economic factors as they relate to space missions, and the outlook for international cooperation.

Obrien, John E.↗

Human Factors, Habitability and Environmental Health and the Human Integration Design Handbook

For decades, Space Life Sciences and NASA as an Agency have considered NASA-STD-3000, Man-Systems Integration Standards, a significant contribution to human spaceflight programs and to human-systems integration in general. The document has been referenced in numerous design standards both within NASA and by organizations throughout the world. With research program and project results being realized, advances in technology and new information in a variety of topic areas now available, the time arrived to update this extensive suite of requirements and design information. During the past several years, a multi-NASA center effort has been underway to write the update to NASA-STD-3000 with standards and design guidance that would be applicable to all future human spaceflight programs. NASA-STD-3001 - Volumes 1 and 2 - and the Human Integration Design Handbook (HIDH) were created. Volume 1, Crew Health, establishes NASA s spaceflight crew health standards for the pre-flight, in-flight, and post-flight phases of human spaceflight. Volume 2, Human Factors, Habitability and Environmental Health, focuses on the requirements of human-system integration and how the human crew interacts with other systems, and how the human and the system function together to accomplish the tasks for mission success. The HIDH is a compendium of human spaceflight history and knowledge, and provides useful background information and research findings. And as the HIDH is a stand-alone companion to the Standards, the maintenance of the document has been streamlined. This unique and flexible approach ensures that the content is current and addresses the fundamental advances of human performance and human capabilities and constraints research. Current work focuses on the development of new sections of Volume 2 and collecting updates to the HIDH. The new sections in development expand the scope of the standard and address mission operations and support operations. This effort is again collaboration with representatives from the Johnson Space Center Missions Operations and Space Life Sciences Directorates and the Engineering Directorate from Kennedy Space Center as well as discipline experts from across the Agency.

Houbec, Keith↗

Computer simulation of the mathematical modeling involved in constitutive equation development: Via symbolic computations

Development of new material models for describing the high temperature constitutive behavior of real materials represents an important area of research in engineering disciplines. Derivation of mathematical expressions (constitutive equations) which describe this high temperature material behavior can be quite time consuming, involved and error prone; thus intelligent application of symbolic systems to facilitate this tedious process can be of significant benefit. A computerized procedure (SDICE) capable of efficiently deriving potential based constitutive models, in analytical form is presented. This package, running under MACSYMA, has the following features: partial differentiation, tensor computations, automatic grouping and labeling of common factors, expression substitution and simplification, back substitution of invariant and tensorial relations and a relational data base. Also limited aspects of invariant theory were incorporated into SDICE due to the utilization of potentials as a starting point and the desire for these potentials to be frame invariant (objective). Finally not only calculation of flow and/or evolutionary laws were accomplished but also the determination of history independent nonphysical coefficients in terms of physically measurable parameters, e.g., Young's modulus, was achieved. The uniqueness of SDICE resides in its ability to manipulate expressions in a general yet predefined order and simplify expressions so as to limit expression growth. Results are displayed when applicable utilizing index notation.

Arnold, S. M.↗

Emerging Fuel Cell Technology Being Developed: Offers Many Benefits to Air Vehicles

Fuel cells, which have recently received considerable attention for terrestrial applications ranging from automobiles to stationary power generation, may enable new aerospace missions as well as offer fuel savings, quiet operations, and reduced emissions for current and future aircraft. NASA has extensive experience with fuel cells, having used them on manned space flight systems over four decades. Consequently, the NASA Glenn Research Center has initiated an effort to investigate and develop fuel cell technologies for multiple aerospace applications. Two promising fuel cell types are the proton exchange membrane (PEM) and solid oxide fuel cell (SOFC). PEM technology, first used on the Gemini spacecraft in the sixties, remained unutilized thereafter until the automotive industry recently recognized the potential. PEM fuel cells are low-temperature devices offering quick startup time but requiring relatively pure hydrogen fuel. In contrast, SOFCs operate at high temperatures and tolerate higher levels of impurities. This flexibility allows SOFCs to use hydrocarbon fuels, which is an important factor considering our current liquid petroleum infrastructure. However, depending on the specific application, either PEM or SOFC can be attractive. As only NASA can, the Agency is pursuing fuel cell technology for civil uninhabited aerial vehicles (UAVs) because it offers enhanced scientific capabilities, including enabling highaltitude, long-endurance missions. The NASA Helios aircraft demonstrated altitudes approaching 100,000 ft using solar power in 2001, and future plans include the development of a regenerative PEM fuel cell to provide nighttime power. Unique to NASA's mission, the high-altitude aircraft application requires the PEM fuel cell to operate on pure oxygen, instead of the air typical of terrestrial applications.

Walker, James F.↗