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At least 631 records · Page 35

Development of A Directed Acyclic Graph for Venous Thromboembolism During Spaceflight

Introduction: Recent studies have reported the development of venous blood flow stasis in astronauts and an occlusive venous thrombosis during spaceflight. Subsequent investigations revealed approximately one quarter of surveilled crew members had some degree of blood flow stasis in the left internal jugular vein. Therefore, NASA’s Human System Risk Board now formally tracks venous thromboembolism (VTE) as a “concern” for human spaceflight. To investigate potential mechanisms by which exposures concomitant with spaceflight (e.g., microgravity, radiation) may contribute to VTE, we developed a causal diagram in the form of a directed acyclic graph (DAG). Methods: The mechanisms by which spaceflight exposures may elevate the risk of VTE and the downstream effects on mission outcomes were critically analyzed, taking into account scientific literature and subject matter expertise consultation, and a DAG was generated. A Level-of-Evidence score for each causal relationship was assigned based on assessing the literature against a set of criteria derived from the A. Bradford Hill Causal Guidelines. Results: The set of three main factors that predispose people to VTE (hypercoagulability, endothelial damage, and blood stasis) is known as Virchow’s Triad. In constructing the DAG for VTE we articulated various mechanisms by which the principal spaceflight hazards (microgravity, radiation, closed hostile environment, isolation and confinement, distance from Earth) are thought to interact with or cause the components in Virchow’s triad. We found sufficient evidence to at least speculate that fluid shifts from microgravity, compensatory alterations in hematologic indices, spaceflight atmospheric conditions, and oxidative stress/inflammation from radiation may be potential contributors to VTE development. Discussion: Developing the DAG entailed a systematic and repeatable approach for visualizing relationships between contributing factors that may lead to VTE in spaceflight. Articulating pathways linking spaceflight exposures to VTE risk factors and possible VTE development enables subject matter experts from different domains to construct a shared mental model. Assignment of levels of evidence scores to the relationships helps identify knowledge and capability gaps that should be considered for further investigation. Furthermore, the DAG highlights modifiable variables and may therefore facilitate the development of new VTE risk mitigation strategies.

Alexander Svoronos↗

Compact extragalactic nonthermal sources.

Results of photometry, polarimetry, spectroscopy, and direct photography at visual wavelengths of four additional objects of the BL Lacertae type are reported together with infrared observations to 10 microns for one of them (OJ 287). The data indicate that these objects are compact sources of nonthermal continuum radiation. They are likely to be extragalactic, and their possible relationship to QSOs is discussed.

Strittmatter, P. A.↗

Albedo distribution on Io's surface

A visual albedo distribution model for all hemispheres of Io's surface has been synthesized from available earth-based and spacecraft image and photometric data. The resulting model indicates some interesting patterns and symmetries on Io's surface: the dark polar caps are shifted off Io's rotational axis and are elliptical rather than circular in shape, with extensions toward the sub-Jupiter and anti-Jupiter points on Io; equatorial bright areas are located approximately on a great circle about Io, the plane of which is tilted approximately 15 deg toward Io longitude 60 deg. These and other indicated features may be clues to understanding the endogenic and exogenic processes that have resulted in Io's present observed surface characteristics.

Nash, D. B.↗

Measurement of solar radius changes

Results of daily photometric measurements of the solar radius from Mt. Wilson over the past seven years are reported. Reduction of the full disk magnetograms yields a formal error of 0.1 arcsec in the boustrophedonic scans in the 5250.2 A FeI line. 150 scan lines comprise each observation; 1,412 observations were made from 1974-1981. Measurement procedures, determination of the scattered light of the optics and the atmosphere, and error calculations are described, noting that days of poor atmospheric visibility are omitted from the data. The horizontal diameter of the sun remains visually fixed while the vertical component changes due to atmospheric diffraction; error accounting for thermal effects, telescope aberrations, and instrument calibration are discussed, and results, within instrument accuracy, indicate no change in the solar radius over the last seven years.

Labonte, B. J.↗

Flow visualization study of a vortex-wing interaction

A flow visualization study in water was completed on the interaction of a streamwise vortex with a laminar boundary layer on a two-dimensional wing. The vortex was generated at the tip of a finite wing at incidence, mounted perpendicular to the main wing, and having the same chord as the main wing. The Reynolds number based on wing chord was about 5000. Two different visualization techniques were used. One involved the injection of two different colored dyes into the vortex and the boundary layer. The other technique utilized hydrogen bubbles as an indicator. The position of the vortex was varied in a directional normal to the wing. The angle of attack of the main wing was varied from -5 to +12.5 deg. The vortex induced noticeable cross flows in the wing boundary layer from a distance equivalent to 0.75 chords. When very close to the wing, the vortex entrained boundary layer fluid and caused a cross flow separation which resulted in a secondary vortex.

Mehta, R. D.↗

Acoustic interactions between an altitude test facility and jet engine plumes: Theory and experiments

The overall objective of the described effort was to develop an understanding of the physical mechanisms involved in the flow/acoustic interactions experienced in full-scale altitude engine test facilities. This is done by conducting subscale experiments and through development of a theoretical model. Model cold jet experiments with an axisymmetric convergent nozzle are performed in a test setup that stimulates a supersonic jet exhausting into a cylindrical diffuser. The measured data consist of detailed flow visualization data and acoustic spectra for a free and a ducted plume. It is shown that duct resonance is most likely responsible by theoretical calculations. Theoretical calculations also indicate that the higher discrete tones observed in the measurements are related to the screech phenomena. Limited experiments on the sensitivity of a free 2-D, C-D nozzle to externally imposed sound are also presented. It is shown that a 2-D, C-D nozzle with a cutback is less excitable than a 2-D C-D nozzle with no cutback. At a pressure ratio of 1.5 unsteady separation from the diverging walls of the nozzle is noticed. This separation switches from one wall to the opposite wall thus providing an unsteady deflection of the plume. It is shown that this phenomenon is related to the venting provided by the cutback section.

Ahuja, K. K.↗

VV 114, a high infrared luminosity interacting galaxy system

VV 114 is a nearby example of a far-infrared (FIR) bright, high luminosity (L(sub FIR) greater than 10(exp 11) solar luminosity) interacting galaxy pair. At a redshift of z = 0.02 it provides an opportunity to study such interacting galaxies at a favorable spatial scale (390 pc/arcsec). This paper presents new high resolution near-infrared (1.25 to 3.7 micrometer) and visible images, and visible spectra of VV 114. A picture emerges of a system with widespread massive star formation throughout both interacting galaxies. The brighter visible galaxy (VV 114W) shows H II region-like emission in both visual spectra and near-infrared colors, with no more than two magnitudes of visual extinction. The brightest peak of infrared and radio emission (VV 114E) has extreme near-infrared colors and is located at a minimum of visible emission. This indicates a large concentration of dust in the nucleus of VV 114E that is nearly entirely obscuring a major luminosity source in this system.

Knop, R. A.↗

An Experimental Study of Characteristic Combustion-Driven Flow for CFD Validation

A series of uni-element rocket injector studies were completed to provide benchmark quality data needed to validate computational fluid dynamic models. A shear coaxial injector geometry was selected as the primary injector for study using gaseous hydrogen/oxygen and gaseous hydrogen/liquid oxygen propellants. Emphasis was placed on the use of nonintrusive diagnostic techniques to characterize the flowfields inside an optically-accessible rocket chamber. Measurements of the velocity and species fields were obtained using laser velocimetry and Raman spectroscopy, respectively. Qualitative flame shape information was also obtained using laser-induced fluorescence excited from OH radicals and laser light scattering studies of aluminum oxide particle seeded combusting flows. The gaseous hydrogen/liquid oxygen propellant studies for the shear coaxial injector focused on breakup mechanisms associated with the liquid oxygen jet under subcritical pressure conditions. Laser sheet illumination techniques were used to visualize the core region of the jet and a Phase Doppler Particle Analyzer was utilized for drop velocity, size and size distribution characterization. The results of these studies indicated that the shear coaxial geometry configuration was a relatively poor injector in terms of mixing. The oxygen core was observed to extend well downstream of the injector and a significant fraction of the mixing occurred in the near nozzle region where measurements were not possible to obtain. Detailed velocity and species measurements were obtained to allow CFD model validation and this set of benchmark data represents the most comprehensive data set available to date. As an extension of the investigation, a series of gas/gas injector studies were conducted in support of the X-33 Reusable Launch Vehicle program. A Gas/Gas Injector Technology team was formed consisting of the Marshall Space Flight Center, the NASA Lewis Research Center, Rocketdyne and Penn State. Injector geometries studied under this task included shear and swirl coaxial configurations as well as an impinging jet injector.

Santoro, Robert J.↗

An Experimental Study of Characteristic Combustion-Driven Flow for CFD Validation

A series of uni-element rocket injector studies were completed to provide benchmark quality data needed to validate computational fluid dynamic models. A shear coaxial injector geometry was selected as the primary injector for study using gaseous hydrogen/oxygen and gaseous hydrogen/liquid oxygen propellants. Emphasis was placed on the use of non-intrusive diagnostic techniques to characterize the flowfields inside an optically-accessible rocket chamber. Measurements of the velocity and species fields were obtained using laser velocimetry and Raman spectroscopy, respectively Qualitative flame shape information was also obtained using laser-induced fluorescence excited from OH radicals and laser light scattering studies of aluminum oxide particle seeded combusting flows. The gaseous hydrogen/liquid oxygen propellant studies for the shear coaxial injector focused on breakup mechanisms associated with the liquid oxygen jet under sub-critical pressure conditions. Laser sheet illumination techniques were used to visualize the core region of the jet and a Phase Doppler Particle Analyzer was utilized for drop velocity, size and size distribution characterization. The results of these studies indicated that the shear coaxial geometry configuration was a relatively poor injector in terms of mixing. The oxygen core was observed to extend well downstream of the injector and a significant fraction of the mixing occurred in the near nozzle region where measurements were not possible to obtain Detailed velocity and species measurements were obtained to allow CFD model validation and this set of benchmark data represents the most comprehensive data set available to date As an extension of the investigation, a series of gas/gas injector studies were conducted in support of the X-33 Reusable Launch Vehicle program. A Gas/Gas Injector Technology team was formed consisting of the Marshall Space Flight Center, the NASA Lewis Research Center, Rocketdyne and Penn State. Injector geometries studied under this task included shear and swirl coaxial configurations as well as an impinging jet injector.

Santoro, Robert J.↗

Chance Encounter with a Stratospheric Kerosene Rocket Plume from Russia over California

During a routine ER-2 aircraft high-altitude test flight on April 18, 1997, an unusual aerosol cloud was detected at 20 km altitude near the California coast at about 370 degrees N latitude. Not visually observed by the ER-2 pilot, the cloud was characterized bv high concentration of soot and sulfate aerosol in a region over 100 km in horizontal extent indicating that the source of the plume was a large hydrocarbon fueled vehicle, most likely a launch vehicle powered only by rocket motors burning liquid oxygen and kerosene. Two Russian Soyuz rockets could conceivably have produced the plume. The first was launched from the Baikonur Cosmodrome, Kazakhstan on April 6th; the second was launched from Plesetsk, Russia on April 9. Air parcel trajectory calculations and long-lived tracer gas concentrations in the cloud indicate that the Baikonur rocket launch is the most probable source of the plume. The parcel trajectory calculations do not unambiguously trace the transport of the Soyuz plume from Asia to North America, illustrating serious flaws in the point-to-point trajectory calculations. This chance encounter represents the only measurement of the stratospheric effects of emissions from a rocket powered exclusively with hydrocarbon fuel.

Newman, P. A.↗

Preliminary Results From a Heavily Instrumented Engine Ice Crystal Icing Test in a Ground Based Altitude Test Facility

Preliminary results from the heavily instrumented ALF502R-5 engine test conducted in the NASA Glenn Research Center Propulsion Systems Laboratory are discussed. The effects of ice crystal icing on a full scale engine is examined and documented. This same model engine, serial number LF01, was used during the inaugural icing test in the Propulsion Systems Laboratory facility. The uncommanded reduction of thrust (rollback) events experienced by this engine in flight were simulated in the facility. Limited instrumentation was used to detect icing on the LF01 engine. Metal temperatures on the exit guide vanes and outer shroud and the load measurement were the only indicators of ice formation. The current study features a similar engine, serial number LF11, which is instrumented to characterize the cloud entering the engine, detect/characterize ice accretion, and visualize the ice accretion in the region of interest. Data were acquired at key LF01 test points and additional points that explored: icing threshold regions, low altitude, high altitude, spinner heat effects, and the influence of varying the facility and engine parameters. For each condition of interest, data were obtained from some selected variations of ice particle median volumetric diameter, total water content, fan speed, and ambient temperature. For several cases the NASA in-house engine icing risk assessment code was used to find conditions that would lead to a rollback event. This study further helped NASA develop necessary icing diagnostic instrumentation, expand the capabilities of the Propulsion Systems Laboratory, and generate a dataset that will be used to develop and validate in-house icing prediction and risk mitigation computational tools. The ice accretion on the outer shroud region was acquired by internal video cameras. The heavily instrumented engine showed good repeatability of icing responses when compared to the key LF01 test points and during day-to-day operation. Other noticeable observations are presented.

Enigine Icing↗

Virtual and Experimental Visualization of Flows in Packed Beds of Spheres Simulating Porous Media Flows

A videotape presentation of flow in a packed bed of spheres is provided. The flow experiment consisted of three principal elements: (1) an oil tunnel 76.2 mm by 76.2 mm in cross section, (2) a packed bed of spheres in regular and irregular arrays, and (3) a flow characterization methodology, either (a) full flow field tracking (FFFT) or (b) computational fluid dynamic (CFD) simulation. The refraction indices of the oil and the test array of spheres were closely matched, and the flow was seeded with aluminum oxide particles. Planar laser light provided a two-dimensional projection of the flow field, and a traverse simulated a three-dimensional image of the entire flow field. Light focusing and reflection rendered the spheres black, permitting visualization of the planar circular interfaces in both the axial and transverse directions. Flows were observed near the wall-sphere interface and within the set of spheres. The CFD model required that a representative section of a packed bed be formed and gridded, enclosing and cutting six spheres so that symmetry conditions could be imposed at all cross-boundaries. Simulations had to be made with the flow direction at right angles to that used in the experiments, however, to take advantage of flow symmetry. Careful attention to detail was required for proper gridding. The flow field was three-dimensional and complex to describe, yet the most prominent finding was flow threads, as computed in the representative 'cube' of spheres with face symmetry and conclusively demonstrated experimentally herein. Random packing and bed voids tended to disrupt the laminar flow, creating vortices.

Hendricks, R. C.↗

Rapid adaptation to Coriolis force perturbations of arm trajectory

1. Forward reaching movements made during body rotation generate tangential Coriolis forces that are proportional to the cross product of the angular velocity of rotation and the linear velocity of the arm. Coriolis forces are inertial forces that do not involve mechanical contact. Virtually no constant centrifugal forces will be present in the background when motion of the arm generates transient Coriolis forces if the radius of body rotation is small. 2. We measured the trajectories of arm movements made in darkness to a visual target that was extinguished as movement began. The reaching movements were made prerotation, during rotation at 10 rpm in a fully enclosed rotating room, and postrotation. During testing the subject was seated at the center of the room and pointed radially. Neither visual nor tactile feedback about movement accuracy was present. 3. In experiment 1, subjects reached at a fast or slow rate and their hands made contact with a horizontal surface at the end of the reach. Their initial perrotary movements were highly significantly deviated relative to prerotation in both trajectories and end-points in the direction of the transient Coriolis forces that had been generated during the reaches. Despite the absence of visual and tactile feedback about reaching accuracy, all subjects rapidly regained straight movement trajectories and accurate endpoints. Postrotation, transient errors of opposite sign were present for both trajectories and endpoints. 4. In a second experiment the conditions were identical except that subjects pointed just above the location of the extinguished target so that no surface contact was involved. All subjects showed significant initial perrotation deviations of trajectories and endpoints in the direction of the transient Coriolis forces. With repeated reaches the trajectories, as viewed from above, again became straight, but there was only partial restoration of endpoint accuracy, so that subjects reached in a straight line to the wrong place. Aftereffects of opposite sign were transiently present in the postrotary movements. 5. These observations fail to support current equilibrium point models, both alpha and lambda, of movement control. Such theories would not predict endpoint errors under our experimental conditions, in which the Coriolis force is absent at the beginning and end of a movement. Our results indicate that detailed aspects of movement trajectory are being continuously monitored on the basis of proprioceptive feedback in relation to motor commands. Adaptive compensations can be initiated after one perturbation despite the absence of either visual or tactile feedback about movement trajectory and endpoint error. Moreover, movement trajectory and end-point can be remapped independently.(ABSTRACT TRUNCATED AT 400 WORDS).

Non-NASA Center↗

Spectrophotometry of beta Lyrae

Two hundred and fourteen scans over the wavelength region 1100 A to 1800 A with 10 A resolution were obtained by OAO spacecraft for the eclipsing binary Beta Lyrae between JD 2440889.5 and JD 2440904.5. Preliminary results indicate that: (1) The intensity at primary minimum is almost exactly one-half that at maximum and that the primary eclipse is less deep than that in the visual or longer ultraviolet wavelengths; (2) except for the 1100 to 1200 A region, the depth of the primary eclipse appears independent of wavelength; (3) the energy distribution at secondary minimum is similar to that at primary; (4) the two most prominent emission lines match well both with Si IV and C IV emission observed in gamma Vel and imply an exciting source of high temperature; (5) the emission lines do not show variation with phase.

Houck, T. E.↗

IUE and visual spectrophotometry of Markarian 9, Markarian 10, and 3C 390.3

Ultraviolet spectra from IUE are combined with visual spectra for the three type I Seyfert galaxies Mrk 9, Mrk 10, and 3C 390.3. The 2175 A interstellar feature is measured well enough in Mrk 9 to indicate that the extinction corresponding to E(B-V) = 0.14 + or - 0.04 is in the galaxy. Mrk 10 displays evidence for 2175 A absorption and also yields E(B-V) = 0.14 + or - 0.07, while the continuum for 3C 390.3 is too weak to positively detect the feature. It is found, after correcting for reddening, that the line-intensity ratio L(alpha)/H(beta) ranges from 8 to 18, while that for H(alpha)/H(beta) goes from 2.1 to 5.4. It is noted that the He II 1640/4686 line ratio is uncertain but appears to be consistent with the recombination value of about 8. If photoionization is assumed, a comparison of the strengths of L(alpha) and H(beta) with the UV ionizing flux suggests that H(beta) is enhanced rather than L(alpha) depressed. When a comparison is made with similar ratios in quasars, L(alpha) is found to be much stronger and H(beta) slightly stronger in Seyferts than in quasars.

Oke, J. B.↗

The design and instrumentation of the Purdue annular cascade facility with initial data acquisition and analysis

Three dimensional aerodynamic data, required to validate and/or indicate necessary refinements to inviscid and viscous analyses of the flow through turbomachine blade rows, are discussed. Instrumentation and capabilities for pressure measurement, probe insertion and traversing, and flow visualization are reviewed. Advanced measurement techniques including Laser Doppler Anemometers, are considered. Data processing is reviewed. Predictions were correlated with the experimental data. A flow visualization technique using helium filled soap bubbles was demonstrated.

Stauter, R. C.↗

Visualization studies of turbulent transition flows in a porous medium

Results are reported for flow-visualization studies of the flow regimes of water passing through a porous medium consisting of cylindrical glass and plexiglas rods arranged in a complex and fixed three-dimensional geometry. The Reynolds number (Re) varied from 50 to 700; the flow was visualized by injecting a 5% potassium permanganate dye solution into the pores and photographing the resulting dye streaklines with both a still camera and a movie camera. The results indicate that four distinct flow regimes exist in the porous medium: (1) Darcy or creeping flow up to Re = 3; (2) steady inertia-dominated laminar flow for Re = 3-150; (3) unsteady transitional laminar flow for Re = 150-250; and (4) fully turbulent flow for Re greater than 250. It is concluded that a laminar wake instability mechanism typical of the external flow about bluff bodies may be responsible for the overall transition from laminar to turbulent flow in porous media.

Bilardo, V. J.↗

Cloud cover typing from environmental satellite imagery. Discriminating cloud structure with Fast Fourier Transforms (FFT)

The use of two dimensional Fast Fourier Transforms (FFTs) subjected to pattern recognition technology for the identification and classification of low altitude stratus cloud structure from Geostationary Operational Environmental Satellite (GOES) imagery was examined. The development of a scene independent pattern recognition methodology, unconstrained by conventional cloud morphological classifications was emphasized. A technique for extracting cloud shape, direction, and size attributes from GOES visual imagery was developed. These attributes were combined with two statistical attributes (cloud mean brightness, cloud standard deviation), and interrogated using unsupervised clustering amd maximum likelihood classification techniques. Results indicate that: (1) the key cloud discrimination attributes are mean brightness, direction, shape, and minimum size; (2) cloud structure can be differentiated at given pixel scales; (3) cloud type may be identifiable at coarser scales; (4) there are positive indications of scene independence which would permit development of a cloud signature bank; (5) edge enhancement of GOES imagery does not appreciably improve cloud classification over the use of raw data; and (6) the GOES imagery must be apodized before generation of FFTs.

Logan, T. L.↗