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At least 649 records · Page 36

Abnormalities of the QT interval in primary disorders of autonomic failure

BACKGROUND: Experimental evidence shows that activation of the autonomic nervous system influences ventricular repolarization and, therefore, the QT interval on the ECG. To test the hypothesis that the QT interval is abnormal in autonomic dysfunction, we examined ECGs in patients with severe primary autonomic failure and in patients with congenital dopamine beta-hydroxylase (DbetaH) deficiency who are unable to synthesize norepinephrine and epinephrine. SUBJECTS AND METHODS: Maximal QT and rate-corrected QT (QTc) intervals and adjusted QTc dispersion [(maximal QTc - minimum QTc on 12 lead ECG)/square root of the number of leads measured] were determined in blinded fashion from ECGs of 67 patients with primary autonomic failure (36 patients with multiple system atrophy [MSA], and 31 patients with pure autonomic failure [PAF]) and 17 age- and sex-matched healthy controls. ECGs of 5 patients with congenital DbetaH deficiency and 6 age- and sex-matched controls were also analyzed. RESULTS: Patients with MSA and PAF had significantly prolonged maximum QTc intervals (492+/-58 ms(1/2) and 502+/-61 ms(1/2) [mean +/- SD]), respectively, compared with controls (450+/-18 ms(1/2), P < .05 and P < .01, respectively). A similar but not significant trend was observed for QT. QTc dispersion was also increased in MSA (40+/-20 ms(1/2), P < .05 vs controls) and PAF patients (32+/-19 ms(1/2), NS) compared with controls (21+/-5 ms(1/2)). In contrast, patients with congenital DbetaH deficiency did not have significantly different RR, QT, QTc intervals, or QTc dispersion when compared with controls. CONCLUSIONS: Patients with primary autonomic failure who have combined parasympathetic and sympathetic failure have abnormally prolonged QT interval and increased QT dispersion. However, QT interval in patients with congenital DbetaH deficiency was not significantly different from controls. It is possible, therefore, that QT abnormalities in patients with primary autonomic failure are not solely caused by lesions of the sympathetic nervous system, and that the parasympathetic nervous system is likely to have a modulatory role in ventricular repolarization.

Non-NASA Center↗

The Earth Science Afternoon Constellation: Preparing for Autonomous but Coordinated Operations

This paper describes how the challenges of coordinating the autonomous operations of geographically dispersed mission control centers for several small and large satellites are being overcome. The Earth Science Afternoon Constellation, also referred to as the "A-Train", is an international grouping of five NASA satellites (two major NASA EOS missions and three NASA/Earth System Science Pathfinder missions) and one French satellite orbiting in close proximity. This grouping of satellites provides scientists with the opportunity to perform coincident observations using data from two or more instruments on various satellites with measurements taken at approximately the same time. Three of the six missions are currently on-orbit, with the two missions expected to join the constellation later this year and one mission in 2007. The operational challenges are daunting for several reasons. There are several Mission Control Centers (widely separated on two continents), operating autonomously under tight budget constraints. All of the Mission Control Centers have reasons to be concerned about safety while flying in close proximity to other satellites, but most Centers did not have the resources or the desire to address this concern alone - the interfaces are too numerous and anticipated operations too costly. Clearly, an efficient approach was needed. This paper describes the steps taken to make this Earth science constellation a reality. Agreements were forged to allow the Mission Control Centers to maintain their autonomy, while ensuring their satellite's safety. Each member mission in the constellation operates independently in accordance with its own mission requirements, but the member missions have agreed to coordinate their operations, i.e., orbital positions and control to ensure the safety of the entire constellation. A centralized system was developed at NASA Goddard Space Flight Center to collect, analyze, and distribute ephemeris data used by each of the mission teams to determine the positions of the satellites in the constellation. The system issues warnings regarding possible dangerous configurations, eliminating the need for redundant capabilities at each Mission Control Center. On-orbit contingency situations were identified and analyzed; agreements were reached in advance of contingency operations to ensure that coordination between the Mission Control Centers can be handled expeditiously and fairly. In this manner, recovery from anomalous situations can be more quickly realized, thereby increasing the science return and reducing costs. The process used to develop these contingency procedures and the systems used to facilitate the contingency resolution are described as well.

Case, Warren↗

RACE pulls for shared control

Maintaining and supporting an aircraft fleet, in a climate of reduced manpower and financial resources, dictates effective utilization of robotics and automation technologies. To help develop a winning robotics and automation program the Air Force Logistics Command created the Robotics and Automation Center of Excellence (RACE). RACE is a command wide focal point. Race is an organic source of expertise to assist the Air Logistic Center (ALC) product directorates in improving process productivity through the judicious insertion of robotics and automation technologies. RACE is a champion for pulling emerging technologies into the aircraft logistic centers. One of those technology pulls is shared control. Small batch sizes, feature uncertainty, and varying work load conspire to make classic industrial robotic solutions impractical. One can view ALC process problems in the context of space robotics without the time delay. The ALC's will benefit greatly from the implementation of a common architecture that supports a range of control actions from fully autonomous to teleoperated. Working with national laboratories and private industry, we hope to transition shared control technology to the depot floor. This paper provides an overview of the RACE internal initiatives and customer support, with particular emphasis on production processes that will benefit from shared control technology.

Leahy, M. B., Jr.↗

Aero Maneuvering Dynamics and Control for Precision Landing on Titan

We have developed and tested several dynamic models of the parafoil system descending in Titan’s atmosphere. These dynamic models include a progression from point mass models to rigid multibody models, including relative dynamics between canopy and payload. In these models, we have included wind models used for Titan simulation, and extrapolated wind gust models previously used for simulation in the Martian environment. We have also developed guidance and control techniques to for autonomous parafoil turning in the adverse wind environment. Finally, and in order to improve the controller performance by reducing the uncertainty to environmental factors, we have also developed ways to estimate the Titan environmental parameters, i.e. the atmospheric density, and the wind magnitude, during the descent. A more complete and realistic simulation is being developed, which uses JPL’s DSENDS Entry, Descent, and Landing Software framework.

Ermolli, Luca↗

Autonomous Information Unit for Fine-Grain Data Access Control and Information Protection in a Net-Centric System

As communication and networking technologies advance, networks will become highly complex and heterogeneous, interconnecting different network domains. There is a need to provide user authentication and data protection in order to further facilitate critical mission operations, especially in the tactical and mission-critical net-centric networking environment. The Autonomous Information Unit (AIU) technology was designed to provide the fine-grain data access and user control in a net-centric system-testing environment to meet these objectives. The AIU is a fundamental capability designed to enable fine-grain data access and user control in the cross-domain networking environments, where an AIU is composed of the mission data, metadata, and policy. An AIU provides a mechanism to establish trust among deployed AIUs based on recombining shared secrets, authentication and verify users with a username, X.509 certificate, enclave information, and classification level. AIU achieves data protection through (1) splitting data into multiple information pieces using the Shamir's secret sharing algorithm, (2) encrypting each individual information piece using military-grade AES-256 encryption, and (3) randomizing the position of the encrypted data based on the unbiased and memory efficient in-place Fisher-Yates shuffle method. Therefore, it becomes virtually impossible for attackers to compromise data since attackers need to obtain all distributed information as well as the encryption key and the random seeds to properly arrange the data. In addition, since policy can be associated with data in the AIU, different user access and data control strategies can be included. The AIU technology can greatly enhance information assurance and security management in the bandwidth-limited and ad hoc net-centric environments. In addition, AIU technology can be applicable to general complex network domains and applications where distributed user authentication and data protection are necessary. AIU achieves fine-grain data access and user control, reducing the security risk significantly, simplifying the complexity of various security operations, and providing the high information assurance across different network domains.

Chow, Edward T.↗

Operational Concepts for Uninhabited Tactical Aircraft

This paper describes experiences with five remotely piloted flight research vehicle projects in the developmental flight test phase. These projects include the Pathfinder, Perseus B, Altus, and X-36 aircraft and the Highly Maneuverable Aircraft Technology (HiMAT). Each of these flight projects was flown at the NASA Dryden Flight Research Center. With the exception of the HiMAT, these projects are a part of the Flight Research Base Research and Technology (R&T) Program of the NASA Aeronautics and Space Transportation Technology Enterprise. Particularly with respect to operational interfaces between the ground-based pilot or operator, this paper draws from those experiences, then provides some rationale for extending the lessons learned during developmental flight research to the possible situations involved in the developmental flights proceeding deployed uninhabited tactical aircraft (UTA) operations. Two types of UTA control approaches are considered: autonomous and remotely piloted. In each of these cases, some level of human operator or pilot control blending is recommended. Additionally, "best practices" acquired over years of piloted aircraft experience are drawn from and presented as they apply to operational UTA.

Deets, Dwain A.↗

Operational Concepts for Uninhabited Tactical Aircraft

This paper describes experiences with five remotely piloted flight research vehicle projects in the developmental flight test phase. These projects include the Pathfinder, Perseus B, Altus, and X-36 aircraft and the Highly Maneuverable Aircraft Technology (HiMAT). Each of these flight projects was flown at the NASA Dryden Flight Research Center. With the exception of the HIMAT, these projects are a part of the Flight Research Base Research and Technology (R&T) Program of the NASA Aeronautics and Space Transportation Technology Enterprise. Particularly with respect to operational interfaces between the ground-based pilot or operator, this paper draws from those experiences, then provides some rationale for extending the lessons learned during developmental flight research to the possible situations involved in the developmental flights proceeding deployed uninhabited tactical aircraft (UTA) operations. Two types of UTA control approaches are considered: autonomous and remotely piloted. In each of these cases, some level of human operator or pilot control blending is recommended. Additionally, "best practices" acquired over years of piloted aircraft experience are drawn from and presented as they apply to operational UTA.

Deets, Dwain A.↗

The effects of autogenic-feedback training on motion sickness severity and heart rate variability in astronauts

Space motion sickness (SMS) affects 50 percent of all people during early days of spaceflight. This study describes the results of two Shuttle flight experiments in which autogenic-feedback training (AFT), a physiological conditioning method, was tested as a treatment for this disorder. Of the six who were designated as flight subjects (two women and four men), three were given treatment and three served as controls (i.e., no AFT). Treatment subjects were given 6 hours of preflight AFT. Preflight results showed that AFT produced a significant increase in tolerance to rotating chair motion sickness tests. Further, this increased tolerance was associated with changes in specific physiological responses and reports of reduced malaise. Flight results showed that two of the three control subjects experienced repeated vomiting on the first mission day, while one subject experienced only moderate malaise. Of the three treatment subjects, one experienced mild discomfort, one moderate discomfort, and one severe motion sickness. Only the three control subjects took medication for symptom suppression. Measures of cardiac function reflective of vagal control were shown to be affected especially strongly on the first day of space flight. AFT given for control of heart rate, respiration, and other autonomic activity influenced both the vagal control measures and SMS. These data suggest that AFT may be an effective treatment for space motion sickness; however, this cannot be demonstrated conclusively with the small number of subjects described.

Toscano, William B.↗

Command and Service Module Communications

This viewgraph presentation examines Command and Service Module (CSM) Communications. The communication system's capabilities are defined, including CSM-Earth, CSM-Lunar Module and CSM-Extravehicular crewman communications. An overview is provided for S-band communications, including data transmission and receiving rates, operating frequencies and major system components (pre-modulation processors, unified S-band electronics, S-band power amplifier and S-band antennas). Additionally, data transmission rates, operating frequencies and the capabilities of VHF communications are described. Major VHF components, including transmitters and receivers, and the VHF multiplexer and antennas are also highlighted. Finally, communications during pre-launch, ascent, in-flight and entry are discussed. Overall, the CSM communication system was rated highly by flight controllers and crew. The system was mostly autonomous for both crew and flight controllers and no major issues were encountered during flight.

Interbartolo, Michael↗

Lyapunov function gradient generated robust control in the absence of the nominal stabilizing control

A relevant facet of the application of Lyapunov gradient-generated robust control to unstable linear autonomous plants is explored. It is demonstrated that if the plant, the output, and the nominal stabilizing control satisfy certain conditions, then the robust component alone stabilizes the nominal plant. An example characterized by two zero eigenvalues and two negative real value poles is presented. These results assure that the robust component will fulfill the role of nominal stabilization successfully so long as the possible magnitude of the robust component can overcome the contribution of the instability to positiveness of the Lyapunov rate.

Blackwell, C. C.↗

Predictive Multiple Model Switching Control with the Self-Organizing Map

A predictive, multiple model control strategy is developed by extension of self-organizing map (SOM) local dynamic modeling of nonlinear autonomous systems to a control framework. Multiple SOMs collectively model the global response of a nonautonomous system to a finite set of representative prototype controls. Each SOM provides a codebook representation of the dynamics corresponding to a prototype control. Different dynamic regimes are organized into topological neighborhoods where the adjacent entries in the codebook represent the global minimization of a similarity metric. The SOM is additionally employed to identify the local dynamical regime, and consequently implements a switching scheme that selects the best available model for the applied control. SOM based linear models are used to predict the response to a larger family of control sequences which are clustered on the representative prototypes. The control sequence which corresponds to the prediction that best satisfies the requirements on the system output is applied as the external driving signal.

Motter, Mark A.↗

Dual-Arm Generalized Compliant Motion With Shared Control

Dual-Arm Generalized Compliant Motion (DAGCM) primitive computer program implementing improved unified control scheme for two manipulator arms cooperating in task in which both grasp same object. Provides capabilities for autonomous, teleoperation, and shared control of two robot arms. Unifies cooperative dual-arm control with multi-sensor-based task control and makes complete task-control capability available to higher-level task-planning computer system via large set of input parameters used to describe desired force and position trajectories followed by manipulator arms. Some concepts discussed in "A Generalized-Compliant-Motion Primitive" (NPO-18134).

Backes, Paul G.↗

Fuzzy Logic Trajectory Design and Guidance for Terminal Area Energy Management

The second generation reusable launch vehicle will leverage many new technologies to make flight to low earth orbit safer and more cost effective. One important capability will be completely autonomous flight during reentry and landing, thus making it unnecessary to man the vehicle for cargo missions with stringent weight constraints. Implementation of sophisticated new guidance and control methods will enable the vehicle to return to earth under less than favorable conditions. The return to earth consists of three phases--Entry, Terminal Area Energy Management (TAEM), and Approach and Landing. The Space Shuttle is programmed to fly all three phases of flight automatically, and under normal circumstances the astronaut-pilot takes manual control only during the Approach and Landing phase. The automatic control algorithms used in the Shuttle for TAEM and Approach and Landing have been developed over the past 30 years. They are computationally efficient, and based on careful study of the spacecraft's flight dynamics, and heuristic reasoning. The gliding return trajectory is planned prior to the mission, and only minor adjustments are made during flight for perturbations in the vehicle energy state. With the advent of the X-33 and X-34 technology demonstration vehicles, several authors investigated implementing advanced control methods to provide autonomous real-time design of gliding return trajectories thus enhancing the ability of the vehicle to adjust to unusual energy states. The bulk of work published to date deals primarily with the approach and landing phase of flight where changes in heading angle are small, and range to the runway is monotonically decreasing. These benign flight conditions allow for model simplification and fairly straightforward optimization. This project focuses on the TAEM phase of flight where mathematically precise methods have produced limited results. Fuzzy Logic methods are used to make onboard autonomous gliding return trajectory design robust to a wider energy envelope, and the possibility of control surface failures, thus increasing the flexibility of unmanned gliding recovery and landing.

Burchett, Bradley↗

Promoting Crew Autonomy: Current Advances and Novel Techniques

Since the dawn of the era of human space flight, mission control centers around the world have played an integral role in guiding space travelers toward mission success. In the International Space Station (ISS) program, astronauts and cosmonauts have the benefit of near constant access to the expertise and resources within mission control, as well as lifeboat capability to quickly return to Earth if something were to go wrong. As we move into an era of longer duration missions to more remote locations, rapid and ready access to mission control on earth will no longer be feasible. To prepare for such missions, long duration crews must be prepared to operate more autonomously, and the mission control paradigm that has been successfully employed for decades must be re-examined. The team at NASA's Payload Operations and Integration Center (POIC) in Huntsville, Alabama is playing an integral role in the development of concepts for a more autonomous long duration crew of the future via research on the ISS.

Harris, Samantha↗

NASA's Autonomous Formation Flying Technology Demonstration, Earth Observing-1(EO-1)

NASA's first autonomous formation flying mission, the New Millennium Program's (NMP) Earth Observing-1 (EO-1) spacecraft, recently completed its principal goal of demonstrating advanced formation control technology. This paper provides an overview of the evolution of an onboard system that was developed originally as a ground mission planning and operations tool. We discuss the Goddard Space Flight Center s formation flying algorithm, the onboard flight design and its implementation, the interface and functionality of the onboard system, and the implementation of a Kalman filter based GPS data smoother. A number of safeguards that allow the incremental phasing in of autonomy and alleviate the potential for mission-impacting anomalies from the on- board autonomous system are discussed. A comparison of the maneuvers planned onboard using the EO-1 autonomous control system to those from the operational ground-based maneuver planning system is presented to quantify our success. The maneuvers discussed encompass reactionary and routine formation maintenance. Definitive orbital data is presented that verifies all formation flying requirements.

Folta, David↗

Dynamic Inversion based Control of a Docking Mechanism

The problem of position and attitude control of the Stewart platform based docking mechanism is considered motivated by its future application in space missions requiring the autonomous docking capability. The control design is initiated based on the framework of the intelligent flight control architecture being developed at NASA Ames Research Center. In this paper, the baseline position and attitude control system is designed using dynamic inversion with proportional-integral augmentation. The inverse dynamics uses a Newton-Euler formulation that includes the platform dynamics, the dynamics of the individual legs along with viscous friction in the joints. Simulation results are presented using forward dynamics simulated by a commercial physics engine that builds the system as individual elements with appropriate joints and uses constrained numerical integration,

Kulkarni, Nilesh V.↗

Teleautonomous guidance for mobile robots

Teleautonomous guidance (TG), a technique for the remote guidance of fast mobile robots, has been developed and implemented. With TG, the mobile robot follows the general direction prescribed by an operator. However, if the robot encounters an obstacle, it autonomously avoids collision with that obstacle while trying to match the prescribed direction as closely as possible. This type of shared control is completely transparent and transfers control between teleoperation and autonomous obstacle avoidance gradually. TG allows the operator to steer vehicles and robots at high speeds and in cluttered environments, even without visual contact. TG is based on the virtual force field (VFF) method, which was developed earlier for autonomous obstacle avoidance. The VFF method is especially suited to the accommodation of inaccurate sensor data (such as that produced by ultrasonic sensors) and sensor fusion, and allows the mobile robot to travel quickly without stopping for obstacles.

Borenstein, J.↗